Page last updated: 2024-08-16

tibolone and 17-ethinyl-7 alpha-methyl-19-nortestosterone

tibolone has been researched along with 17-ethinyl-7 alpha-methyl-19-nortestosterone in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (83.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Delbressine, LP; Kloosterboer, HJ; Timmer, CJ; van Iersel, ML; Verheul, HA1
Delbressine, LP; Kloosterboer, HJ; van Iersel, ML; Verheul, HA1
Kloosterboer, HJ; Löfgren, L; Verheul, HA; von Schoultz, B; von Schoulz, E1
Blok, LJ; Burger, CW; Hanifi-Moghaddam, P; Kloosterboer, HJ; Verheul, HA1
Auzou, G; Balaguer, P; Cavaillès, V; Escande, A; Kloosterboer, H; Maudelonde, T; Rabenoelina, F; Servant, N1
Basar, M; Bozkurt, I; Buchwalder, L; Guzel, E; Kayisli, U; Lockwood, CJ; Ocak, N; Schatz, F1

Trials

2 trial(s) available for tibolone and 17-ethinyl-7 alpha-methyl-19-nortestosterone

ArticleYear
Estrogen and tibolone metabolite levels in blood and breast tissue of postmenopausal women recently diagnosed with early-stage breast cancer and treated with tibolone or placebo for 14 days.
    Reproductive sciences (Thousand Oaks, Calif.), 2007, Volume: 14, Issue:2

    Topics: Aged; Androstenols; Breast; Breast Neoplasms; Chromatography, Liquid; Double-Blind Method; Estradiol; Estrenes; Estrone; Female; Gas Chromatography-Mass Spectrometry; Humans; Middle Aged; Neoplasm Staging; Norpregnenes; Postmenopause; Selective Estrogen Receptor Modulators; Tandem Mass Spectrometry; Tissue Distribution

2007
Levels of tibolone and estradiol and their nonsulfated and sulfated metabolites in serum, myometrium, and vagina of postmenopausal women following treatment for 21 days with tibolone, estradiol, or estradiol plus medroxyprogestrone acetate.
    Reproductive sciences (Thousand Oaks, Calif.), 2007, Volume: 14, Issue:2

    Topics: Aged; Estradiol; Estrone; Female; Humans; Medroxyprogesterone Acetate; Middle Aged; Myometrium; Norpregnenes; Postmenopause; Selective Estrogen Receptor Modulators; Tissue Distribution; Uterine Prolapse; Vagina

2007

Other Studies

4 other study(ies) available for tibolone and 17-ethinyl-7 alpha-methyl-19-nortestosterone

ArticleYear
Pharmacokinetic parameters of tibolone and metabolites in plasma, urine, feces, and bile from ovariectomized cynomolgus monkeys after a single dose or multiple doses of tibolone.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:7

    Topics: Administration, Oral; Animals; Bile; Biotransformation; Chromatography, High Pressure Liquid; Drug Administration Schedule; Feces; Female; Gas Chromatography-Mass Spectrometry; Macaca fascicularis; Norpregnenes; Ovariectomy; Reproducibility of Results; Selective Estrogen Receptor Modulators; Sulfates; Tandem Mass Spectrometry

2007
Selective tissue distribution of tibolone metabolites in mature ovariectomized female cynomolgus monkeys after multiple doses of tibolone.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:7

    Topics: Administration, Oral; Animals; Biotransformation; Brain; Breast; Chromatography, High Pressure Liquid; Drug Administration Schedule; Female; Gas Chromatography-Mass Spectrometry; Macaca fascicularis; Molecular Structure; Norpregnenes; Ovariectomy; Reproducibility of Results; Selective Estrogen Receptor Modulators; Sulfates; Tandem Mass Spectrometry; Tissue Distribution; Uterus; Vagina

2007
Regulation of activities of steroid hormone receptors by tibolone and its primary metabolites.
    The Journal of steroid biochemistry and molecular biology, 2009, Volume: 116, Issue:1-2

    Topics: Androgens; Cell Line; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogen Receptor Modulators; Genes, Reporter; Humans; Luciferases; Norpregnanes; Norpregnenes; Receptors, Androgen; Receptors, Progesterone; Receptors, Steroid

2009
Effects of tibolone and its metabolites on prolactin and insulin-like growth factor binding protein-1 expression in human endometrial stromal cells.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2015, Volume: 31, Issue:5

    Topics: Blotting, Western; Contraceptive Agents, Female; Dexamethasone; Endometrium; Enzyme-Linked Immunosorbent Assay; Estradiol; Estrenes; Estrogen Receptor Modulators; Estrogens; Female; Furans; Glucocorticoids; Hormone Antagonists; Humans; Insulin-Like Growth Factor Binding Protein 1; Medroxyprogesterone Acetate; Mifepristone; Norpregnanes; Norpregnenes; Prolactin; Real-Time Polymerase Chain Reaction; RNA, Messenger; Stromal Cells

2015