tibenelast has been researched along with theophylline in 2 studies
*Theophylline: A methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP. [MeSH]
*Theophylline: A methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bury, T; Corhay, JL; Louis, R; Radermecker, M | 1 |
| Bowsher, RR; Cerimele, BJ; McNay, JL; Rowe, H; Schwertschlag, US | 1 |
1 trial(s) available for tibenelast and theophylline
| Article | Year |
|---|---|
Effect of tibenelast (a phosphodiesterase inhibitor) and theophylline on isoproterenol-stimulated heart rate, cyclic AMP and norepinephrine levels.
Topics: Adult; Blood Pressure; Cyclic AMP; Dose-Response Relationship, Drug; Heart Rate; Humans; Isoproterenol; Male; Middle Aged; Norepinephrine; Phosphodiesterase Inhibitors; Regression Analysis; Theophylline; Thiophenes | 1993 |
1 other study(ies) available for tibenelast and theophylline
| Article | Year |
|---|---|
LY 186655, a phosphodiesterase inhibitor, inhibits histamine release from human basophils, lung and skin fragments.
Topics: Adult; Basophils; Bronchodilator Agents; Histamine Release; Humans; Immunoglobulin E; In Vitro Techniques; Lung; Skin; Theophylline; Thiophenes | 1992 |