tiagabine hydrochloride has been researched along with sk&f 89976-a in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andersen, KE; Braestrup, C; Grønwald, FC; Jørgensen, AS; Knutsen, LJ; Nielsen, EB; Sonnewald, U; Suzdak, PD; Sørensen, PO | 1 |
| Andersen, KE; Henry, RF; Knutsen, LJ; Lau, J; Lundt, BF; Morton, HE; Naerum, L; Petersen, H; Stephensen, H; Suzdak, PD; Swedberg, MD; Sørensen, PO; Thomsen, C | 1 |
| Andersen, KE; Huusfeldt, PO; Knutsen, LJ; Lau, J; Lundt, BF; Petersen, H; Suzdak, PD; Swedberg, MD; Sørensen, JL | 1 |
| Andersen, KE; Huusfeldt, PO; Lau, J; Lundt, BF; Petersen, H; Suzdak, PD; Swedberg, MD; Sørensen, JL | 1 |
4 other study(ies) available for tiagabine hydrochloride and sk&f 89976-a
| Article | Year |
|---|---|
The synthesis of novel GABA uptake inhibitors. 1. Elucidation of the structure-activity studies leading to the choice of (R)-1-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]-3-piperidinecarboxylic acid (tiagabine) as an anticonvulsant drug candidate.
Topics: Animals; Anticonvulsants; GABA Antagonists; gamma-Aminobutyric Acid; Molecular Structure; Nicotinic Acids; Nipecotic Acids; Proline; Prosencephalon; Rats; Stereoisomerism; Structure-Activity Relationship; Synaptosomes; Tiagabine | 1993 |
Synthesis of novel GABA uptake inhibitors. 3. Diaryloxime and diarylvinyl ether derivatives of nipecotic acid and guvacine as anticonvulsant agents.
Topics: Animals; Anticonvulsants; Carrier Proteins; Crystallography, X-Ray; Drug Design; Ethers; GABA Antagonists; GABA Plasma Membrane Transport Proteins; Membrane Proteins; Membrane Transport Proteins; Models, Molecular; Molecular Structure; Nicotinic Acids; Nipecotic Acids; Organic Anion Transporters; Oximes; Proline; Rats; Structure-Activity Relationship; Synaptic Transmission | 1999 |
Synthesis of novel GABA uptake inhibitors. 4. Bioisosteric transformation and successive optimization of known GABA uptake inhibitors leading to a series of potent anticonvulsant drug candidates.
Topics: Animals; Anticonvulsants; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Rats; Seizures; Structure-Activity Relationship; Synaptosomes | 1999 |
Synthesis of novel gamma-aminobutyric acid (GABA) uptake inhibitors. 5.(1) Preparation and structure-activity studies of tricyclic analogues of known GABA uptake inhibitors.
Topics: Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Brain Chemistry; Carbolines; Convulsants; Female; gamma-Aminobutyric Acid; Mice; Neuroglia; Neurons; Neurotransmitter Uptake Inhibitors; Postural Balance; Rats; Seizures; Structure-Activity Relationship; Synaptosomes | 2001 |