tiagabine has been researched along with snap 5114 in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 7 (63.64) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Borden, LA; Branchek, TA; Dhar, TG; Gluchowski, C; Smith, KE; Tyagarajan, S; Weinshank, RL | 1 |
| Höfner, G; Kragler, A; Wanner, KT | 1 |
| Faust, MR; Höfner, G; Pabel, J; Wanner, KT | 1 |
| Filipek, B; Guzior, N; Höfner, GC; Kowalczyk, P; Kulig, K; Sałat, K; Wanner, KT | 1 |
| Höfner, G; Renukappa-Gutke, T; Steffan, T; Wanner, KT | 1 |
| Borkar, N; Clausen, RP; Ecker, GF; Jurik, A; Jørgensen, L; Madsen, KK; Nielsen, B; Rosatelli, E; Schousboe, A; Vogensen, SB | 1 |
| Höfner, G; Tóth, K; Wanner, KT | 2 |
| Hauke, TJ; Höfner, G; Wanner, KT | 1 |
| Fijałkowski, Ł; Furgała, A; Gryzło, B; Höfner, GC; Kulig, K; Malawska, B; Malawska, K; Nowaczyk, A; Podkowa, A; Rapacz, A; Sałat, K; Wanner, KT; Zaręba, P; Żmudzki, P | 1 |
| Bajda, M; Filipek, B; Höfner, GC; Jóźwiak, K; Kotniewicz, K; Kulig, K; Latacz, G; Maj, M; Malawska, B; Podkowa, A; Rapacz, A; Sałat, K; Wanner, KT; Zaręba, P; Łątka, K | 1 |
11 other study(ies) available for tiagabine and snap 5114
| Article | Year |
|---|---|
Design, synthesis and evaluation of substituted triarylnipecotic acid derivatives as GABA uptake inhibitors: identification of a ligand with moderate affinity and selectivity for the cloned human GABA transporter GAT-3.
Topics: Animals; Binding Sites; Biological Transport; Blood-Brain Barrier; Carrier Proteins; Cell Line; Cloning, Molecular; Drug Design; GABA Antagonists; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Humans; Ligands; Membrane Proteins; Membrane Transport Proteins; Nipecotic Acids; Organic Anion Transporters; Proline; Rats | 1994 |
Synthesis and biological evaluation of aminomethylphenol derivatives as inhibitors of the murine GABA transporters mGAT1-mGAT4.
Topics: Animals; Benzylamines; Cell Line; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; Humans; Methylation; Mice; Molecular Structure; Structure-Activity Relationship | 2008 |
Azetidine derivatives as novel gamma-aminobutyric acid uptake inhibitors: synthesis, biological evaluation, and structure-activity relationship.
Topics: Animals; Azetidines; Biological Transport; Cattle; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; Inhibitory Concentration 50; Structure-Activity Relationship | 2010 |
2-Substituted 4-hydroxybutanamides as potential inhibitors of γ-aminobutyric acid transporters mGAT1-mGAT4: synthesis and biological evaluation.
Topics: Amides; Animals; Behavior, Animal; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; HEK293 Cells; Humans; Male; Mice; Mice, Knockout; Protein Binding; Protein Isoforms | 2013 |
Design, synthesis and SAR studies of GABA uptake inhibitors derived from 2-substituted pyrrolidine-2-yl-acetic acids.
Topics: Animals; Dose-Response Relationship, Drug; Drug Design; GABA Plasma Membrane Transport Proteins; HEK293 Cells; Humans; Mice; Molecular Structure; Proline; Structure-Activity Relationship | 2015 |
Structure activity relationship of selective GABA uptake inhibitors.
Topics: Amino Acids; Animals; Carrier Proteins; GABA Agonists; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; HEK293 Cells; Humans; Ligands; Mice; Molecular Docking Simulation; Molecular Structure; Nipecotic Acids; Protein Isoforms; Structure-Activity Relationship; Tiagabine | 2015 |
Synthesis and biological evaluation of novel N-substituted nipecotic acid derivatives with an alkyne spacer as GABA uptake inhibitors.
Topics: Alkynes; Animals; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; HEK293 Cells; Humans; Mice; Nipecotic Acids; Protein Isoforms; Structure-Activity Relationship | 2018 |
Generation and screening of pseudostatic hydrazone libraries derived from 5-substituted nipecotic acid derivatives at the GABA transporter mGAT4.
Topics: Animals; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; HEK293 Cells; Humans; Hydrazones; Mice; Molecular Structure; Nipecotic Acids; Small Molecule Libraries; Structure-Activity Relationship | 2019 |
Synthesis and biological evaluation of novel N-substituted nipecotic acid derivatives with a cis-alkene spacer as GABA uptake inhibitors.
Topics: Alkenes; Animals; Drug Design; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; HEK293 Cells; Humans; Mice; Nipecotic Acids; Stereoisomerism; Structure-Activity Relationship; Tiagabine | 2019 |
Novel mouse GABA uptake inhibitors with enhanced inhibitory activity toward mGAT3/4 and their effect on pain threshold in mice.
Topics: Analgesics; Animals; Diabetes Mellitus, Experimental; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; Hyperalgesia; Male; Mice; Molecular Docking Simulation; Molecular Structure; Neuralgia; Oxaliplatin; Pain Threshold; Protein Binding; Streptozocin; Structure-Activity Relationship | 2020 |
Development of tricyclic N-benzyl-4-hydroxybutanamide derivatives as inhibitors of GABA transporters mGAT1-4 with anticonvulsant, antinociceptive, and antidepressant activity.
Topics: Amides; Analgesics; Anticonvulsants; Antidepressive Agents; Dose-Response Relationship, Drug; Drug Development; GABA Uptake Inhibitors; Humans; Molecular Structure; N-Acetylglucosaminyltransferases; Structure-Activity Relationship | 2021 |