Page last updated: 2024-08-24

tiagabine and isoxazoles

tiagabine has been researched along with isoxazoles in 31 studies

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	7 (22.58)	18.2507
2000's	20 (64.52)	29.6817
2010's	4 (12.90)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Diemer, NH; Johansen, FF	1
Patsalos, PN; Sander, JW	1
Bialer, M; Perucca, E	1
Chadwick, DW; Kadir, ZA; Marson, AG	1
Chadwick, DW; Kadir, Z; Marson, T	1
White, HS	1
Perucca, E	1
Vajda, FJ	1
Johannessen, SI; Nakken, KO; Rytter, E	1
Calabrese, JR; Kroeker, G; Kusumakar, V; Rao, R; Scarrow, G; Yatham, LN	1
Boon, PA; van Rijckevorsel, K	1
Sirven, JI	1
Bergin, AM; Connolly, M	1
Shelton, RC	1
Johannessen, SI; Perucca, E	1
Helmers, SL; LaRoche, SM	1
Abou-Khalil, B; Bautista, J; Bazil, C; Bergen, D; Beydoun, A; Bourgeois, B; Browne, T; Faught, RE; Fischer, JH; French, JA; Gidal, B; Glauser, TA; Harden, CL; Hirtz, D; Kanner, AM; Marks, WJ; Montouris, GD; Nespeca, M; Sachdeo, RC; Schachter, SC; Stern, J; Theodore, WH; Turk, WR; Wilner, A	3
Yatham, LN	1
Steiger, A	1
Feuerstein, TJ; Stefan, H	1
Johannessen, SI; Tomson, T	1
Clausen, RP; Frølund, B; Krogsgaard-Larsen, P; Larsson, OM; Saunders, GW; Schousboe, A; Smith, MD; White, HS; Wilcox, KS	1
Hutson, PH; McDonald, LM; Sheppard, WF; Sohal, B; Staveley, SM; Tattersall, FD	1
Pellock, JM	1
Walsh, JK	1
Clausen, RP; Ebert, B; Krogsgaard-Larsen, P; Madsen, KK; Schousboe, A; White, HS	1
Clausen, RP; Danbolt, NC; Guo, C; Holen, T; Holmseth, S; Hua, R; Laake, P; Lehre, AC; Madsen, KK; Olofsson, AM; Poblete-Naredo, I; Rowley, NM; Rusakov, DA; Schousboe, A; White, HS; Zhou, Y	1
Hiramatsu, M	1
Lingford-Hughes, A; Muthukumaraswamy, S; Myers, J; Nutt, D; Papadopoulos, A; Wilson, S	1

Reviews

24 review(s) available for tiagabine and isoxazoles

Article	Year
Newer antiepileptic drugs. Towards an improved risk-benefit ratio. Drug safety, 1994, Volume: 11, Issue:1 Topics: Acetamides; Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Piracetam; Propylene Glycols; Risk Factors; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide	1994
The clinical pharmacokinetics of the newer antiepileptic drugs. Focus on topiramate, zonisamide and tiagabine. Clinical pharmacokinetics, 1996, Volume: 31, Issue:1 Topics: Anticonvulsants; Drug Interactions; Fructose; Half-Life; Humans; Isoxazoles; Nipecotic Acids; Tiagabine; Topiramate; Zonisamide	1996
New antiepileptic drugs: a systematic review of their efficacy and tolerability. BMJ (Clinical research ed.), 1996, Nov-09, Volume: 313, Issue:7066 Topics: Acetates; Adolescent; Adult; Aged; Amines; Anticonvulsants; Child; Cross-Over Studies; Cyclohexanecarboxylic Acids; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Male; Middle Aged; Nipecotic Acids; Randomized Controlled Trials as Topic; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin; Zonisamide	1996
Clinical administration of new antiepileptic drugs: an overview of safety and efficacy. Epilepsia, 1996, Volume: 37 Suppl 6 Topics: Acetates; Amines; Anticonvulsants; Confidence Intervals; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Therapy, Combination; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Odds Ratio; Placebos; Randomized Controlled Trials as Topic; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide	1996
Comparative anticonvulsant and mechanistic profile of the established and newer antiepileptic drugs. Epilepsia, 1999, Volume: 40 Suppl 5 Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Epilepsies, Partial; Felbamate; Fructose; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Receptors, GABA; Sodium Channels; Synaptic Transmission; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide	1999
The clinical pharmacokinetics of the new antiepileptic drugs. Epilepsia, 1999, Volume: 40 Suppl 9 Topics: Acetates; Amines; Anticonvulsants; Biological Availability; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Zonisamide	1999
New antiepileptic drugs. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2000, Volume: 7, Issue:2 Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide	2000
[Adverse effects of antiepileptic agents]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2000, Oct-30, Volume: 120, Issue:26 Topics: Acetates; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Clobazam; Cyclohexanecarboxylic Acids; Drug Utilization; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Norway; Piracetam; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide	2000
Third generation anticonvulsants in bipolar disorder: a review of efficacy and summary of clinical recommendations. The Journal of clinical psychiatry, 2002, Volume: 63, Issue:4 Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Double-Blind Method; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Placebos; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide	2002
Antiepileptic drug therapy for adults: when to initiate and how to choose. Mayo Clinic proceedings, 2002, Volume: 77, Issue:12 Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Propylene Glycols; Recurrence; Risk Factors; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide	2002
New antiepileptic drug therapies. Neurologic clinics, 2002, Volume: 20, Issue:4 Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Phenytoin; Piracetam; Propylene Glycols; Thiazines; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide	2002
Treating bipolar depression. The Journal of family practice, 2003, Volume: Suppl Topics: Acetates; Affect; Amines; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Lithium Compounds; Nipecotic Acids; Olanzapine; Oxcarbazepine; Pirenzepine; Tiagabine; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Zonisamide	2003
The ideal pharmacokinetic properties of an antiepileptic drug: how close does levetiracetam come? Epileptic disorders : international epilepsy journal with videotape, 2003, Volume: 5 Suppl 1 Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Half-Life; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide	2003
The new antiepileptic drugs: scientific review. JAMA, 2004, Feb-04, Volume: 291, Issue:5 Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Propylene Glycols; Tiagabine; Topiramate; Triazines; Zonisamide	2004
Efficacy and tolerability of the new antiepileptic drugs, I: Treatment of new-onset epilepsy: report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy Society. Epilepsia, 2004, Volume: 45, Issue:5 Topics: Acetates; Adolescent; Adult; Age Factors; Amines; Antipsychotic Agents; Carbamazepine; Child; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Approval; Epilepsies, Partial; Epilepsy, Absence; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Piracetam; Tiagabine; Topiramate; Triazines; United States; United States Food and Drug Administration; Zonisamide	2004
Efficacy and tolerability of the new antiepileptic drugs, II: Treatment of refractory epilepsy: report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy Society. Epilepsia, 2004, Volume: 45, Issue:5 Topics: Acetates; Adolescent; Adult; Age Factors; Amines; Anticonvulsants; Carbamazepine; Child; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Approval; Epilepsies, Partial; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Piracetam; Practice Patterns, Physicians'; Tiagabine; Topiramate; Triazines; United States; United States Food and Drug Administration; Zonisamide	2004
Efficacy and tolerability of the new antiepileptic drugs II: treatment of refractory epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epile Neurology, 2004, Apr-27, Volume: 62, Issue:8 Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Child; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Drug Resistance; Epilepsies, Partial; Epilepsy, Generalized; Evidence-Based Medicine; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Piracetam; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide	2004
Newer anticonvulsants in the treatment of bipolar disorder. The Journal of clinical psychiatry, 2004, Volume: 65 Suppl 10 Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Depressive Disorder; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenytoin; Piracetam; Pregabalin; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide	2004
Neurochemical regulation of sleep. Journal of psychiatric research, 2007, Volume: 41, Issue:7 Topics: Brain; Corticotropin-Releasing Hormone; Electroencephalography; Estrogens; GABA Agonists; GABA-A Receptor Agonists; Growth Hormone-Releasing Hormone; Hormone Replacement Therapy; Humans; Hypnotics and Sedatives; Hypothalamo-Hypophyseal System; Isoxazoles; Neuropeptides; Nipecotic Acids; Pituitary-Adrenal System; Sleep Initiation and Maintenance Disorders; Sleep Stages; Tiagabine	2007
Novel anticonvulsant drugs. Pharmacology & therapeutics, 2007, Volume: 113, Issue:1 Topics: Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Piracetam; Pregabalin; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide	2007
Pharmacokinetic variability of newer antiepileptic drugs: when is monitoring needed? Clinical pharmacokinetics, 2006, Volume: 45, Issue:11 Topics: Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Interactions; Drug Monitoring; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Piracetam; Pregabalin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide	2006
New pharmacotherapies for pediatric seizures. Pediatric annals, 2004, Volume: 33, Issue:6 Topics: Adolescent; Amines; Animals; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Pediatrics; Piracetam; Tiagabine; Topiramate; Treatment Outcome; Triazines; Vigabatrin; Zonisamide	2004
Enhancement of slow wave sleep: implications for insomnia. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2009, Apr-15, Volume: 5, Issue:2 Suppl Topics: Electroencephalography; GABA Agonists; Humans; Isoxazoles; Nipecotic Acids; Sleep Deprivation; Sleep Initiation and Maintenance Disorders; Sleep Stages; Tiagabine	2009
[Functional role for GABA transporters in the CNS]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2014, Volume: 143, Issue:4 Topics: Animals; Brain; Camphanes; Carbazoles; Carrier Proteins; Central Nervous System Diseases; Drug Discovery; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; Humans; Isoxazoles; Mental Disorders; Molecular Targeted Therapy; Nipecotic Acids; Piperidines; Tiagabine	2014

Trials

2 trial(s) available for tiagabine and isoxazoles

Article	Year
Third generation anticonvulsants in bipolar disorder: a review of efficacy and summary of clinical recommendations. The Journal of clinical psychiatry, 2002, Volume: 63, Issue:4 Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Double-Blind Method; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Placebos; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide	2002
Differences between magnetoencephalographic (MEG) spectral profiles of drugs acting on GABA at synaptic and extrasynaptic sites: a study in healthy volunteers. Neuropharmacology, 2015, Volume: 88 Topics: Adult; Brain; Brain Waves; Cross-Over Studies; Female; GABA Agonists; gamma-Aminobutyric Acid; Humans; Isoxazoles; Magnetoencephalography; Male; Nipecotic Acids; Pyridines; Rest; Single-Blind Method; Synapses; Tiagabine; Young Adult; Zolpidem	2015

Article

Year

Third generation anticonvulsants in bipolar disorder: a review of efficacy and summary of clinical recommendations.

The Journal of clinical psychiatry, 2002, Volume: 63, Issue:4

Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Cyclohexanecarboxylic Acids; Double-Blind Method; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Nipecotic Acids; Placebos; Tiagabine; Topiramate; Treatment Outcome; Triazines; Zonisamide

2002

Differences between magnetoencephalographic (MEG) spectral profiles of drugs acting on GABA at synaptic and extrasynaptic sites: a study in healthy volunteers.

Neuropharmacology, 2015, Volume: 88

Topics: Adult; Brain; Brain Waves; Cross-Over Studies; Female; GABA Agonists; gamma-Aminobutyric Acid; Humans; Isoxazoles; Magnetoencephalography; Male; Nipecotic Acids; Pyridines; Rest; Single-Blind Method; Synapses; Tiagabine; Young Adult; Zolpidem

2015

Other Studies

6 other study(ies) available for tiagabine and isoxazoles

Article	Year
Enhancement of GABA neurotransmission after cerebral ischemia in the rat reduces loss of hippocampal CA1 pyramidal cells. Acta neurologica Scandinavica, 1991, Volume: 84, Issue:1 Topics: Animals; Arousal; Brain Ischemia; Cell Count; Cell Survival; Diazepam; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hippocampus; Isoxazoles; Male; Motor Activity; Nerve Degeneration; Neurons; Nipecotic Acids; Rats; Rats, Inbred Strains; Synaptic Transmission; Tiagabine	1991
The 'number needed to treat' with levetiracetam (LEV): comparison with the other new antiepileptic drugs (AEDs). Seizure, 2002, Volume: 11 Suppl A Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Piracetam; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide	2002
Inhibition of the betaine-GABA transporter (mGAT2/BGT-1) modulates spontaneous electrographic bursting in the medial entorhinal cortex (mEC). Epilepsy research, 2008, Volume: 79, Issue:1 Topics: Animals; Carrier Proteins; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Entorhinal Cortex; Evoked Potentials; GABA Agonists; GABA Plasma Membrane Transport Proteins; In Vitro Techniques; Isoxazoles; Kainic Acid; Male; Nipecotic Acids; Rats; Rats, Sprague-Dawley; Status Epilepticus; Tiagabine	2008
Discriminative stimulus effects of tiagabine and related GABAergic drugs in rats. Psychopharmacology, 2008, Volume: 197, Issue:4 Topics: Administration, Oral; Amines; Animals; Anticonvulsants; Azabicyclo Compounds; Baclofen; Benzodiazepines; Bicuculline; Brain; Cyclohexanecarboxylic Acids; Discrimination Learning; Dose-Response Relationship, Drug; GABA Agents; GABA Agonists; GABA Antagonists; GABA Plasma Membrane Transport Proteins; Gabapentin; gamma-Aminobutyric Acid; Generalization, Stimulus; Hypnotics and Sedatives; Injections, Intraperitoneal; Isoxazoles; Male; Nipecotic Acids; Piperazines; Pyridines; Rats; Thiophenes; Tiagabine; Zolpidem	2008
Selective GABA transporter inhibitors tiagabine and EF1502 exhibit mechanistic differences in their ability to modulate the ataxia and anticonvulsant action of the extrasynaptic GABA(A) receptor agonist gaboxadol. The Journal of pharmacology and experimental therapeutics, 2011, Volume: 338, Issue:1 Topics: Animals; Anticonvulsants; Ataxia; Dose-Response Relationship, Drug; Female; GABA Agonists; GABA Plasma Membrane Transport Proteins; Isoxazoles; Male; Mice; Nipecotic Acids; Receptors, GABA-A; Synapses; Tiagabine	2011
Deletion of the betaine-GABA transporter (BGT1; slc6a12) gene does not affect seizure thresholds of adult mice. Epilepsy research, 2011, Volume: 95, Issue:1-2 Topics: Animals; Anticonvulsants; Convulsants; Crosses, Genetic; Dose-Response Relationship, Drug; Electroshock; Exons; Female; GABA Plasma Membrane Transport Proteins; Isoxazoles; Kindling, Neurologic; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nipecotic Acids; Pentylenetetrazole; RNA, Messenger; Seizures; Tiagabine	2011