Page last updated: 2024-08-22

tiadenol and clofibrate

tiadenol has been researched along with clofibrate in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199024 (85.71)18.7374
1990's3 (10.71)18.2507
2000's0 (0.00)29.6817
2010's1 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Clenet, M; Cuchet, P; Fredj, G; Rousselet, F; Rozé, C1
Czarnecki, SK; Kritchevsky, D; Story, JA; Tepper, SA1
Colombo, L; Goldberg, D; Monarca, A; Zanetta, R1
Nicrosini, F; Pasotti, C1
Ceccato, S; Cucinotta, D; Palummeri, E; Passeri, M1
Cuchet, P; Debray, C; Rozé, C; Souchard, M; Vaille, C1
Mikalsen, SO; Rivedal, E; Sanner, T1
Kaalhus, O; Mikalsen, SO; Reith, A; Sanner, T1
Holen, I; Mikalsen, SO; Sanner, T1
Boiteux-Antoine, AF; Fournel-Gigleux, S; Knehr, M; Magdalou, J; Oesch, F; Post, K; Schladt, L; Siest, G; Thomas, H1
Kawashima, Y; Kozuka, H; Uy-Yu, N1
Hirose, A; Katoh, H; Kawashima, Y; Kozuka, H; Takegishi, M; Watanuki, H1
Hirose, A; Kawashima, Y; Kozuka, H2
Dostert, P; Hartmann, R; Oesch, F; Schladt, L; Strolin-Benedetti, M; Timms, C; Wörner, W1
Isono, H; Katoh, H; Kawashima, Y; Kozuka, H; Watanuki, H1
Clenet, M; Fredj, G; Rousselet, F2
Oesch, F; Schladt, L1
Aarsaether, N; Berge, RK; Lillehaug, JR; Male, R1
Basílico, MZ; Chicco, A; de Rodi, MA; Gutman, R; Lombardo, YB; Nusimovich, B1
Katoh, H; Kawashima, Y; Kozuka, H; Tachibana, Y; Takegishi, M; Watanuki, H1
Berge, RK; Flatmark, T; Osmundsen, H1
Battistin, P; Colli, S; Gianfranceschi, G; Maderna, P; Malacrida, MG; Montanari, G; Morazzoni, G; Sirtori, CR; Sirtori, M; Tremoli, E1
Giorcelli, G; Icardi, GP; Vacha, G1
Bakke, OM; Berge, RK1
Cand, F; Cuchet, P; Keriel, C; Morrier, C1

Trials

1 trial(s) available for tiadenol and clofibrate

ArticleYear
Clofibrate and tiadenol treatment in hyperlipoproteinemias. A comparative trial of drugs affecting lipoprotein catabolism and biosynthesis.
    Atherosclerosis, 1983, Volume: 49, Issue:2

    Topics: Adult; Aged; Blood Glucose; Clinical Trials as Topic; Clofibrate; Fatty Alcohols; Female; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Lipoprotein Lipase; Lipoproteins; Male; Middle Aged; Platelet Aggregation; Uric Acid

1983

Other Studies

27 other study(ies) available for tiadenol and clofibrate

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Action of tiadenol and clofibrate on biliary excretions of cholesterol and bile salts in rats.
    Digestion, 1979, Volume: 19, Issue:4

    Topics: Animals; Bile; Bile Acids and Salts; Body Weight; Cholesterol; Clofibrate; Fatty Alcohols; Hypolipidemic Agents; Liver; Male; Organ Size; Phospholipids; Rats; Secretory Rate

1979
Influence of tiadenol, bis-(hydroxyethylthio)1,10-decane, on cholesterol metabolism in rats.
    Pharmacological research communications, 1979, Volume: 11, Issue:10

    Topics: Animals; Anticholesteremic Agents; Cholesterol; Clofibrate; Fatty Alcohols; Feces; In Vitro Techniques; Lipid Metabolism; Liver; Male; Rats

1979
[Tolerability and side-effects of bis-(hydroxy-2-ethylthio)-1,10-decane (BS 530) as compared with clofibrate in the therapy of hyperlipemia].
    La Clinica terapeutica, 1979, Oct-31, Volume: 91, Issue:2

    Topics: Clofibrate; Fatty Alcohols; Gastrointestinal Diseases; Headache; Humans; Hyperlipidemias; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Hypolipidemic Agents; Muscular Diseases; Pain

1979
[Clinical study of thiadenol in diabetic hyperdyslipemia as compared with clofibrate].
    La Clinica terapeutica, 1979, Aug-15, Volume: 90, Issue:3

    Topics: Adult; Aged; Clofibrate; Diabetes Complications; Fatty Alcohols; Female; Humans; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged

1979
[Bis-(hydroxy-2-ethylthyo)-1,10-decano in hyperlipaemic therapy (author's transl)].
    Giornale italiano di cardiologia, 1977, Volume: 7, Issue:3

    Topics: Adult; Aged; Cholesterol; Clofibrate; Decanoates; Drug Evaluation; Drug Tolerance; Fatty Alcohols; Female; Humans; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged; Platelet Aggregation; Triglycerides

1977
The effects of tiadenol, clofibrate and clofibride on bile composition in the rat.
    European journal of pharmacology, 1977, May-01, Volume: 43, Issue:1

    Topics: Amides; Animals; Bile; Bile Acids and Salts; Body Weight; Cholesterol; Clofibrate; Fatty Alcohols; Hypolipidemic Agents; Lipids; Liver; Male; Organ Size; Phospholipids; Rats; Taurocholic Acid; Time Factors

1977
Hepatic peroxisome proliferators induce morphologic transformation of Syrian hamster embryo cells, but not peroxisomal beta oxidation.
    Progress in clinical and biological research, 1991, Volume: 369

    Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Clofibrate; Cricetinae; Diethylhexyl Phthalate; Digitonin; Embryo, Mammalian; Fatty Alcohols; Hypolipidemic Agents; Liver; Mesocricetus; Microbodies; Nicotinic Acids; Rats; Tetradecanoylphorbol Acetate

1991
Role of catalase and oxidative stress in hepatic peroxisome proliferator-induced morphological transformation of Syrian hamster embryo cells.
    International journal of cancer, 1990, Nov-15, Volume: 46, Issue:5

    Topics: Amitrole; Animals; Catalase; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Clofibrate; Cricetinae; Diethylhexyl Phthalate; Electron Spin Resonance Spectroscopy; Fatty Alcohols; Hydrogen Peroxide; Liver; Mesocricetus; Microbodies; Vitamin K

1990
Morphological transformation and catalase activity of Syrian hamster embryo cells treated with hepatic peroxisome proliferators, TPA and nickel sulphate.
    Cell biology and toxicology, 1990, Volume: 6, Issue:1

    Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Animals; Catalase; Cells, Cultured; Clofibrate; Cricetinae; Diethylhexyl Phthalate; Embryo, Mammalian; Fatty Alcohols; Hypolipidemic Agents; Nickel; Phthalic Acids; Tetradecanoylphorbol Acetate

1990
Effect of hypolipidemic compounds on lauric acid hydroxylation and phase II enzymes.
    Biochemical pharmacology, 1989, Jun-15, Volume: 38, Issue:12

    Topics: Animals; Aspirin; Clofibrate; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Cytosol; Epoxide Hydrolases; Fatty Alcohols; Glucuronosyltransferase; Glutathione Transferase; Guinea Pigs; Hypolipidemic Agents; Imidazoles; Male; Microbodies; Microsomes, Liver; Mixed Function Oxygenases; Rats; Rats, Inbred F344

1989
Sex-related differences in the enhancing effects of perfluoro-octanoic acid on stearoyl-CoA desaturase and its influence on the acyl composition of phospholipid in rat liver. Comparison with clofibric acid and tiadenol.
    The Biochemical journal, 1989, Nov-01, Volume: 263, Issue:3

    Topics: Animals; Caprylates; Clofibrate; Dose-Response Relationship, Drug; Enzyme Induction; Fatty Acid Desaturases; Fatty Alcohols; Female; Fluorocarbons; Liver; Male; Microbodies; Phospholipids; Rats; Sex Factors; Stearoyl-CoA Desaturase; Testosterone

1989
Concomitant increase by peroxisome proliferators of fatty acid-binding protein, peroxisomal beta-oxidation and cytosolic acyl-CoA hydrolase in liver.
    Research communications in chemical pathology and pharmacology, 1985, Volume: 49, Issue:2

    Topics: Animals; Carrier Proteins; Cell Division; Clofibrate; Clofibric Acid; Cytosol; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Alcohols; Guinea Pigs; Liver; Male; Mice; Mice, Inbred Strains; Microbodies; Molecular Weight; Neoplasm Proteins; Nerve Tissue Proteins; Oxidation-Reduction; Palmitoyl-CoA Hydrolase; Rats; Rats, Inbred Strains; Thiolester Hydrolases

1985
Alterations by peroxisome proliferators of acyl composition of hepatic phosphatidylcholine in rats, mice and guinea-pigs. Role of stearoyl-CoA desaturase.
    The Biochemical journal, 1986, Apr-01, Volume: 235, Issue:1

    Topics: Acyl Coenzyme A; Acyltransferases; Animals; Clofibrate; Clofibric Acid; Fatty Acid Desaturases; Fatty Alcohols; Guinea Pigs; Liver; Mice; Microbodies; Microsomes, Liver; Palmitoyl Coenzyme A; Phosphatidylcholines; Rats; Rats, Inbred Strains; Species Specificity; Stearoyl-CoA Desaturase

1986
Concomitant induction of cytosolic but not microsomal epoxide hydrolase with peroxisomal beta-oxidation by various hypolipidemic compounds.
    Biochemical pharmacology, 1987, Feb-01, Volume: 36, Issue:3

    Topics: Animals; Aspirin; Clofibrate; Cytosol; Dose-Response Relationship, Drug; Enzyme Induction; Epoxide Hydrolases; Fatty Alcohols; Fenofibrate; Hepatomegaly; Hypolipidemic Agents; Imidazoles; Liver; Male; Microbodies; Microsomes, Liver; Oxidation-Reduction; Palmitoyl-CoA Hydrolase; Probucol; Rats; Rats, Inbred F344

1987
Effects of clofibric acid and tiadenol on cytosolic long-chain acyl-CoA hydrolase and peroxisomal beta-oxidation in liver and extrahepatic tissues of rats.
    Biochimica et biophysica acta, 1987, Jul-31, Volume: 920, Issue:2

    Topics: Animals; Brain; Clofibrate; Clofibric Acid; Cytosol; Esterases; Fatty Alcohols; Intestinal Mucosa; Liver; Male; Microbodies; Oxidation-Reduction; Oxidoreductases; Palmitoyl-CoA Hydrolase; Rats; Rats, Inbred Strains; Testis; Thiolester Hydrolases; Tissue Distribution

1987
[Comparative effects of clofibrate and tiadenol on the metabolism of cholesterol in rats and hamsters. I. Comparative action of clofibrate and tiadenol on hepatic and intestinal biosynthesis of cholesterol in hamsters and rats].
    Annales pharmaceutiques francaises, 1986, Volume: 44, Issue:4

    Topics: Animals; Cholesterol; Clofibrate; Cricetinae; Fatty Alcohols; Hypolipidemic Agents; Intestinal Mucosa; Liver; Male; Mesocricetus; Rats; Rats, Inbred Strains

1986
[Comparative effects of clofibrate and tiadenol on the metabolism of cholesterol in rats. II. Comparative action of clofibrate and tiadenol on biliary and fecal excretion of cholesterol and its metabolites in rats].
    Annales pharmaceutiques francaises, 1986, Volume: 44, Issue:5

    Topics: Animals; Bile; Cholesterol; Clofibrate; Fatty Alcohols; Feces; Hypolipidemic Agents; Male; Rats; Rats, Inbred Strains

1986
Coordinate induction of peroxisomal beta-oxidation activity and cytosolic epoxide hydrolase activity.
    Pharmacology & therapeutics, 1987, Volume: 33, Issue:1

    Topics: Animals; Aspirin; Benzimidazoles; Clofibrate; Cytosol; Enzyme Induction; Epoxide Hydrolases; Fatty Alcohols; Hypolipidemic Agents; Male; Microbodies; Oxidation-Reduction; Rats; Rats, Inbred F344; Rats, Inbred Strains; Species Specificity; Temperature

1987
Peroxisome proliferators show tumor-promoting but no direct transforming activity in vitro.
    International journal of cancer, 1986, Jan-15, Volume: 37, Issue:1

    Topics: Adipose Tissue; Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Clofibrate; Dose-Response Relationship, Drug; Fatty Alcohols; Hypolipidemic Agents; Mice; Microbodies; Nicotinic Acids; Tetradecanoylphorbol Acetate

1986
Effects of tiadenol and clofibrate on plasma post heparin lipolytic hepatic, extrahepatic and monoglyceride hydrolase activities in rats with hypertriglyceridemia induced by a sucrose rich diet.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1985, Volume: 17, Issue:4

    Topics: Animals; Clofibrate; Fatty Alcohols; Heparin; Hyperlipidemias; Lipase; Lipolysis; Lipoprotein Lipase; Liver; Male; Monoacylglycerol Lipases; Rats; Rats, Inbred Strains; Triglycerides

1985
Effect of clofibric acid and tiadenol on peroxisomal beta-oxidation and fatty acid binding protein in intestinal mucosa of rats.
    Toxicology and applied pharmacology, 1985, Volume: 78, Issue:3

    Topics: Administration, Oral; Animals; Catalase; Clofibrate; Clofibric Acid; Electrophoresis, Polyacrylamide Gel; Fatty Alcohols; Intestinal Mucosa; Liver; Male; Oleic Acid; Oleic Acids; Oxidation-Reduction; Palmitoyl Coenzyme A; Protein Binding; Rats; Rats, Inbred Strains

1985
Enhancement of long-chain acyl-CoA hydrolase activity in peroxisomes and mitochondria of rat liver by peroxisomal proliferators.
    European journal of biochemistry, 1984, Jun-15, Volume: 141, Issue:3

    Topics: Animals; Centrifugation, Density Gradient; Centrifugation, Isopycnic; Clofibrate; Enzyme Induction; Fatty Alcohols; Liver; Lysosomes; Male; Microbodies; Mitochondria, Liver; Palmitoyl-CoA Hydrolase; Rats; Rats, Inbred Strains; Subcellular Fractions; Thiolester Hydrolases

1984
Selective increase in acylation of 1-acylglycerophosphorylcholine in livers of rats and mice by peroxisome proliferators.
    Biochimica et biophysica acta, 1984, Apr-18, Volume: 793, Issue:2

    Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Acylation; Acyltransferases; Animals; Aspirin; Clofibrate; Clofibric Acid; Fatty Alcohols; Glycerylphosphorylcholine; Guinea Pigs; Hypolipidemic Agents; Liver; Lysophosphatidylcholines; Male; Mice; Microbodies; Microsomes, Liver; Rats; Rats, Inbred Strains

1984
Drug treatment of hypertriglyceridaemia in chronic uraemic patients: preliminary report on D,L-carnitine and thiadenol.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1980, Volume: 17

    Topics: Carnitine; Chronic Disease; Clofibrate; Fatty Alcohols; Humans; Hyperlipoproteinemias; Lipid Metabolism; Renal Dialysis; Uremia

1980
Changes in lipid metabolizing enzymes of hepatic subcellular fractions from rats treated with tiadenol and clofibrate.
    Biochemical pharmacology, 1981, Aug-15, Volume: 30, Issue:16

    Topics: Animals; Clofibrate; Fatty Alcohols; Hypolipidemic Agents; Lipid Metabolism; Liver; Male; Organ Size; Proteins; Rats; Rats, Inbred Strains; Subcellular Fractions

1981
Effects of clofibrate and tiadenol on the elimination of lipids and bile acids in rat bile.
    Lipids, 1981, Volume: 16, Issue:10

    Topics: Animals; Bile; Bile Acids and Salts; Clofibrate; Dose-Response Relationship, Drug; Fatty Alcohols; Female; Hypolipidemic Agents; Lipid Metabolism; Male; Organ Size; Rats; Rats, Inbred Strains; Sex Factors

1981