thyroxine glucuronide has been researched along with thyroxine in 8 studies
*Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism. [MeSH]
*Thyroxine: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism. [MeSH]
| Studies (thyroxine glucuronide) | Trials (thyroxine glucuronide) | Recent Studies (post-2010) (thyroxine glucuronide) | Studies (thyroxine) | Trials (thyroxine) | Recent Studies (post-2010) (thyroxine) |
|---|---|---|---|---|---|
| 8 | 0 | 2 | 38,989 | 1,410 | 6,550 |
| Protein | Taxonomy | thyroxine glucuronide (IC50) | thyroxine (IC50) |
|---|---|---|---|
| Transthyretin | Homo sapiens (human) | 2.1939 | |
| UDP-glucuronosyltransferase 1A1 | Homo sapiens (human) | 5.25 | |
| Solute carrier organic anion transporter family member 4C1 | Homo sapiens (human) | 8 | |
| Bile acid receptor | Homo sapiens (human) | 7.86 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barter, RA; Klaassen, CD | 1 |
| De Sandro, V; Ducrotoy, G; Lurier, D; Pacaud, E; Richert, L | 1 |
| Hays, MT; Hsu, L | 1 |
| Bonthuis, F; Docter, R; Pigmans, IG; Rutgers, M; Visser, TJ | 1 |
| Innocenti, F; RamÃrez, J; Ratain, MJ; Yoder Graber, AL | 1 |
| Hays, MT | 1 |
| Buitendijk, M; Galton, VA | 1 |
| Aoki, H; Imazu, T; Minato, K; Nagao, H; Sasaki, M; Takahashi, K | 1 |
8 other study(ies) available for thyroxine glucuronide and thyroxine
| Article | Year |
|---|---|
Rat liver microsomal UDP-glucuronosyltransferase activity toward thyroxine: characterization, induction, and form specificity.
Topics: Animals; Enzyme Induction; Glucuronates; Glucuronosyltransferase; In Vitro Techniques; Iodine Radioisotopes; Male; Microsomes, Liver; Rats; Rats, Inbred Strains; Thyroxine | 1992 |
Determination of 125I-labelled thyroxine glucuronide by reversed-phase high-performance liquid chromatography using on-line radiochemical detection to determine UDPglucuronosyltransferase activity.
Topics: Animals; Chromatography, High Pressure Liquid; Glucuronates; Glucuronosyltransferase; Iodine Radioisotopes; Kinetics; Male; Microsomes, Liver; Radiochemistry; Rats; Rats, Inbred Strains; Thyroxine | 1991 |
Preparation and separation of the glucuronide and sulfate conjugates of thyroxine and triiodothyronine.
Topics: Animals; Cats; Chromatography; Chromatography, High Pressure Liquid; Dextrans; Glucuronates; Glucuronidase; In Vitro Techniques; Iodine Radioisotopes; Sulfates; Thyroxine; Triiodothyronine | 1987 |
Effects of propylthiouracil on the biliary clearance of thyroxine (T4) in rats: decreased excretion of 3,5,3'-triiodothyronine glucuronide and increased excretion of 3,3',5'-triiodothyronine glucuronide and T4 sulfate.
Topics: Animals; Bile; Chromatography, High Pressure Liquid; Glucuronates; Propylthiouracil; Rats; Thyroxine; Triiodothyronine | 1989 |
UGT1A1*28 genotype affects the in-vitro glucuronidation of thyroxine in human livers.
Topics: Camptothecin; DNA, Complementary; Flavonoids; Genotype; Glucuronates; Glucuronides; Glucuronosyltransferase; Humans; Kinetics; Liver; Microsomes, Liver; Phenotype; Piperidines; Polymorphism, Genetic; Thyroxine | 2007 |
Deconjugation of thyroxine glucuronide by the rat kidney.
Topics: Animals; Bile; Glucuronates; Kidney; Liver; Male; Rats; Rats, Sprague-Dawley; Thyroxine; Tissue Distribution | 2009 |
Is the kidney a major storage site for thyroxine as thyroxine glucuronide?
Topics: Animals; Glucuronates; Glucuronidase; Kidney; Liver; Mice; Mice, Knockout; Thyroxine | 2012 |
Effects of triiodothyronine on turnover rate and metabolizing enzymes for thyroxine in thyroidectomized rats.
Topics: Animals; Brain; Glucuronates; Glucuronosyltransferase; Homeostasis; Kidney; Liver; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thyroidectomy; Thyroxine; Triiodothyronine | 2014 |