thymine has been researched along with pyrimidinones in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (40.48) | 18.7374 |
| 1990's | 2 (4.76) | 18.2507 |
| 2000's | 10 (23.81) | 29.6817 |
| 2010's | 11 (26.19) | 24.3611 |
| 2020's | 2 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| McGhee, JD; von Hippel, PH | 1 |
| McCloskey, JA; Puzo, G; Schram, KH | 1 |
| Cech, D; Hein, L; Langen, P; Otto, A; von Janta-Lipinski, M; Wuttke, R | 1 |
| Kalich, J; Raake, W | 1 |
| Doetsch, PW; Franklin, WA; Haseltine, WA | 1 |
| Geller, M; Kulakowska, I; Lesyng, B; Wierzchowski, KL | 1 |
| Bailey, P; Bryant, S; Burrs, A; Doctor, VM | 1 |
| Heidelberger, C | 1 |
| Kuo, I; Ward, JF | 1 |
| Brown, GM; Culp, LA; Dore, E | 1 |
| Varghese, AJ | 1 |
| Rhoades, DF; Wang, SY | 2 |
| Flippen, JL; Gilardi, RD; Karle, IL; Rhoades, DF; Wang, SY | 1 |
| Agarwal, DP; Eickhoff, K; Goedde, HW | 1 |
| Behrman, EJ; Subbaraman, J; Subbaraman, LR | 1 |
| Egerton, RF; Misra, M | 1 |
| Horsfall, MJ; Lawrence, CW | 1 |
| Danel, K; Nielsen, C; Pedersen, EB | 1 |
| Jokić, M; Katalenić, D; Raza, Z | 1 |
| Rappaport, HP | 1 |
| Baskunov, VB; Gerasimov, DN; Gromova, ES; Khoroshaev, AV; Shchyolkina, AK; Subach, OM | 1 |
| Brown, T; Fox, KR; Powers, VE; Ranasinghe, RT; Rusling, DA | 1 |
| Betz, SF; Chen, C; Lio, FM; Reinhart, GJ; Struthers, RS | 1 |
| Ayabe, T | 1 |
| Alberty, RA | 1 |
| Miura, S; Nishizawa, S; Ono, K; Teramae, N; Watanabe, M | 1 |
| Nishizawa, S; Rajendar, B; Rajendran, A; Sato, Y; Teramae, N | 1 |
| Burda, JV; Futera, Z; Klenko, J; Sponer, J; Sponer, JE | 1 |
| Chen, JM; Eisenberg, G; Geleziunas, R; Guo, H; Hayes, J; Kim, CU; Kim, HS; Lansdon, EB; Lee, CK; Lee, IY; Mitchell, ML; Paul, A; Son, JC; Wang, J; Wang, M; Xu, L | 1 |
| Chen, JM; Cho, EJ; Geleziunas, R; Graupe, D; Guo, H; Hayes, J; He, GX; Im, YA; Kim, CU; Lansdon, EB; Mitchell, ML; Paul, A; Rhodes, G; Son, JC; Wang, J; Wang, M; Xu, L | 1 |
| Frey, HM; Leutwyler, S; Lobsiger, S | 1 |
| Ai, C; Hao, M; Li, Y; Mao, Y; Zhang, S | 1 |
| Wincel, H | 1 |
| Brutschy, B; Göbel, M; Kunitski, M; Nosenko, Y; Stark, T; Tarakeshwar, P | 1 |
| Cadet, J; Douki, T; Eriksson, LA; Grand, A; Jorge, N; Labet, V; Morell, C | 1 |
| Johnston, P; Nishikami, Y; Saito, K | 1 |
| Jian, Y; Li, L; Lin, G; Ouyang, H | 1 |
| Aida, M; Ishiyama, S; Katahira, M; Kusano, S; Lam, SL; Mashima, T; Miyamoto, K; Nagatsugi, F | 1 |
| Barone, V; Biczysko, M; Bloino, J; Fornaro, T | 1 |
| Lhiaubet-Vallet, V; Miranda, MA; Rodríguez-Muñiz, GM | 1 |
| Chuang, J; Fakih, M; Gong, J; Li, SM; Wang, C | 1 |
2 review(s) available for thymine and pyrimidinones
| Article | Year |
|---|---|
Chemical carcinogenesis, chemotherapy: cancer's continuing core challenges--G. H. A. Clowes Memorial Lecture.
Topics: Animals; Antineoplastic Agents; Arginase; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Deoxyribonucleases; DNA; Fluorouracil; Humans; Liver Neoplasms; Methylcholanthrene; Mice; Mutation; Neoplasms; Neoplasms, Experimental; Nucleosides; Oncogenic Viruses; Orotic Acid; Phenanthrenes; Protein Binding; Pyrimidinones; Rats; Skin Neoplasms; Thymine; Uracil | 1970 |
[An outline of GnRH analogue].
Topics: Animals; Buserelin; Drug Design; Gonadotropin-Releasing Hormone; Goserelin; Humans; Leuprolide; Phenylurea Compounds; Pyrimidinones; Thymine | 2006 |
1 trial(s) available for thymine and pyrimidinones
| Article | Year |
|---|---|
A Phase I Clinical Trial of Trametinib in Combination with TAS-102 in Patients with Chemotherapy-Resistant RAS-Mutated (PIK3CA/PTEN-Wild Type) Metastatic Colorectal Cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Class I Phosphatidylinositol 3-Kinases; Colorectal Neoplasms; Drug Combinations; Humans; PTEN Phosphohydrolase; Pyridones; Pyrimidinones; Pyrrolidines; Thymine; Trifluridine | 2022 |
39 other study(ies) available for thymine and pyrimidinones
| Article | Year |
|---|---|
Formaldehyde as a probe of DNA structure. II. Reaction with endocyclic imino groups of DNA bases.
Topics: Chemical Phenomena; Chemistry; Deoxyribonucleosides; DNA; Formaldehyde; Hydrogen-Ion Concentration; Imines; Inosine Nucleotides; Kinetics; Polynucleotides; Pyrimidinones; Thermodynamics; Thymine; Thymine Nucleotides; Uracil; Uracil Nucleotides | 1975 |
Incorporation of oxygen-18 into nucleosides and bases.
Topics: Hypoxanthines; Isotope Labeling; Mass Spectrometry; Oxygen Isotopes; Pyrimidinones; Thymine; Time Factors; Uracil; Uridine | 1977 |
Synthesis of substituted 5-fluoro-5,6-dihydropyrimidines.
Topics: Fluorine; Mass Spectrometry; Methods; Pyrimidinones; Thymine; Uracil | 1975 |
[Effect of pseudothymine as a food additive on the growth of rats and swine].
Topics: Animal Feed; Animals; Chlortetracycline; Female; Food Additives; Growth; Male; Pyrimidinones; Rats; Swine; Thymine | 1975 |
Structural determination of the ultraviolet light-induced thymine-cytosine pyrimidine-pyrimidone (6-4) photoproduct.
Topics: Cytosine; DNA; Magnetic Resonance Spectroscopy; Photochemistry; Pyrimidines; Pyrimidinones; Spectrophotometry, Atomic; Spectrophotometry, Infrared; Thymine; Ultraviolet Rays | 1985 |
Dipole moments of 2,4-diketopyrimidines. II. Uracil, thymine and their derivatives.
Topics: Chemical Phenomena; Chemistry, Physical; Chlorine; Dioxanes; Ethyl Ethers; Evaluation Studies as Topic; Fluorouracil; Isomerism; Light; Mathematics; Nitro Compounds; Optics and Photonics; Pyrimidines; Pyrimidinones; Spectrophotometry, Infrared; Thymine; Uracil | 1974 |
Separation of nucleotides, nucleosides and bases of DNA with cation exchange columns.
Topics: Adenine; Animals; Cattle; Chromatography, Ion Exchange; Cytosine; Cytosine Nucleotides; Deoxyadenosines; Deoxycytidine; Deoxyribonucleases; Deoxyribonucleosides; Deoxyribonucleotides; DNA; Evaluation Studies as Topic; Formates; Guanine; Hydrolysis; Methods; Purines; Pyrimidinones; Quaternary Ammonium Compounds; Spectrophotometry, Ultraviolet; Thymidine; Thymine; Thymine Nucleotides; Thymus Gland | 1973 |
Effect of chloride ions on the gamma-radiation induced destruction of nucleic acid bases in aqueous solution. UCLA 12-724.
Topics: Chemical Phenomena; Chemistry; Chlorides; Cytosine; Free Radicals; Pyrimidinones; Radiation Effects; Thymine; Uracil | 1969 |
Methylated bases in DNA of animal origin.
Topics: Animals; Carbon Isotopes; Chick Embryo; Chromatography, Ion Exchange; Chromatography, Paper; Culture Techniques; Cytosine; DNA; DNA, Neoplasm; Guanine; HeLa Cells; Humans; L Cells; Lung; Methionine; Methylation; Peptide Hydrolases; Purinones; Pyrimidinones; Thymine | 1970 |
5-Thyminyl-5,6-dihydrothymine from DNA irradiated with ultraviolet light.
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; DNA; Free Radicals; Infrared Rays; Magnetic Resonance Spectroscopy; Models, Chemical; Pyrimidinones; Radiation Effects; Spectrophotometry; Spectrum Analysis; Thymine; Thymus Gland; Ultraviolet Rays | 1970 |
Uracil-thymine adduct from a mixture of uracil and thymine irradiated with ultraviolet light.
Topics: DNA; Infrared Rays; Magnetic Resonance Spectroscopy; Photochemistry; Pyrimidinones; Radiation Effects; Spectrum Analysis; Thymine; Ultraviolet Rays; Uracil | 1970 |
Pyrimidine phototetramer.
Topics: Cyclization; Photochemistry; Polymers; Pyrimidinones; Thymine | 1971 |
Crystal and molecular structure of a pyrimidine phototetramer.
Topics: Crystallography; Polymers; Pyrimidinones; Thymine | 1971 |
Enzymatic preparation of labeled intermediates of thymine catabolism: dihydrothymine and beta-uridoisobutyric acid.
Topics: Aminoisobutyric Acids; Animals; Carbon Isotopes; Chromatography, Thin Layer; Liver; Propionates; Pyrimidinones; Swine; Thymine; Urea | 1968 |
The reaction of nucleic acid components with m-chloroperoxybenzoic acid.
Topics: Adenine; Benzoates; Chemical Phenomena; Chemistry; Chlorine; Chromatography, Paper; Chromatography, Thin Layer; Cyclic N-Oxides; Hydrogen-Ion Concentration; Kinetics; Nucleic Acids; Nucleosides; Nucleotides; Osmolar Concentration; Peroxides; Potentiometry; Pyrimidinones; Spectrophotometry; Temperature; Thymidine; Thymine; Ultraviolet Rays; Uracil; Uridine | 1969 |
Assessment of electron irradiation damage to biomolecules by electron diffraction and electron energy-loss spectroscopy.
Topics: Adenine; Amino Acids; Cysteine; Cytosine; Electrons; Methionine; Microscopy, Electron; Pyrimidinones; Spectrum Analysis; Thymine; Uracil; Valine | 1984 |
Accuracy of replication past the T-C (6-4) adduct.
Topics: Base Sequence; Cytosine; DNA Damage; DNA Mutational Analysis; DNA Replication; Models, Genetic; Molecular Sequence Data; Pyrimidines; Pyrimidinones; SOS Response, Genetics; Thymine; Ultraviolet Rays | 1994 |
Synthesis and anti-HIV-1 activity of novel 2,3-dihydro-7H-thiazolo[3,2-a]pyrimidin-7-ones.
Topics: Alkylation; Anti-HIV Agents; Cell Line; HIV Reverse Transcriptase; HIV-1; Humans; Magnetic Resonance Spectroscopy; Mesylates; Pyrimidines; Pyrimidinones; Reverse Transcriptase Inhibitors; T-Lymphocytes; Thiazoles; Thymine; Uracil; Virus Replication | 1998 |
The synthesis of novel 6,5- and 6,6-membered fused heterocyclic compounds derived from thymine.
Topics: Drug Design; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Pyridines; Pyrimidine Nucleosides; Pyrimidinones; Thymine | 2000 |
The fidelity of replication of the three-base-pair set adenine/thymine, hypoxanthine/cytosine and 6-thiopurine/5-methyl-2-pyrimidinone with T7 DNA polymerase.
Topics: Adenine; Base Pairing; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; Hypoxanthine; Kinetics; Mercaptopurine; Models, Genetic; Purines; Pyrimidinones; Research Design; Sensitivity and Specificity; Thymine | 2004 |
2-Pyrimidinone as a probe for studying the EcoRII DNA methyltransferase-substrate interaction.
Topics: Cytosine; DNA; DNA-Cytosine Methylases; Molecular Structure; Nucleic Acid Denaturation; Protein Binding; Pyrimidinones; Thermodynamics; Thymine | 2004 |
Recognition of CG inversions in DNA triple helices by methylated 3H-pyrrolo[2,3-d]pyrimidin-2(7H)-one nucleoside analogues.
Topics: Base Pairing; Cytosine; DNA; Guanine; Hydrogen Bonding; Nucleic Acid Conformation; Nucleosides; Oligonucleotides; Pyrimidinones; Thymine | 2005 |
Overlapping, nonidentical binding sites of different classes of nonpeptide antagonists for the human gonadotropin-releasing hormone receptor.
Topics: Amino Acid Sequence; Animals; Binding Sites; Chlorocebus aethiops; COS Cells; Humans; Indoles; Ligands; Models, Molecular; Molecular Sequence Data; Mutation; Peptides; Phenylurea Compounds; Point Mutation; Protein Structure, Secondary; Protein Structure, Tertiary; Pyrimidinones; Radioligand Assay; Receptors, LHRH; Sequence Homology, Amino Acid; Structure-Activity Relationship; Thymine | 2006 |
Thermodynamic properties of enzyme-catalyzed reactions involving cytosine, uracil, thymine, and their nucleosides and nucleotides.
Topics: Catalysis; Cytosine; Enzymes; Hydrolysis; Models, Chemical; Pyrimidine Nucleosides; Pyrimidine Nucleotides; Pyrimidinones; Thermodynamics; Thymine; Uracil | 2007 |
A surface plasmon resonance sensor based on 3,5-diaminopyrazine with a high selectivity for thymine in AP site-containing DNA duplex.
Topics: DNA; DNA Probes; Ligands; Polymorphism, Single Nucleotide; Pyrazines; Pyrimidinones; Surface Plasmon Resonance; Thymine | 2008 |
Effect of methyl substitution in a ligand on the selectivity and binding affinity for a nucleobase: a case study with isoxanthopterin and its derivatives.
Topics: Binding Sites; Calorimetry; Cytosine; Ligands; Methylation; Pyrimidinones; Thermodynamics; Thymine; Xanthopterin | 2009 |
Interactions of the "piano-stool" [ruthenium(II) (eta6-arene)(en)CL]+ complexes with water and nucleobases; ab initio and DFT study.
Topics: Adenine; Antineoplastic Agents; Binding Sites; Cytosine; Ethylenediamines; Guanine; Models, Molecular; Molecular Structure; Purines; Pyrimidinones; Quantum Theory; Ruthenium; Thermodynamics; Thymine; Uracil; Water | 2009 |
N1-Heterocyclic pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
Topics: Animals; Anti-HIV Agents; Binding Sites; Crystallography, X-Ray; Dogs; Heterocyclic Compounds; HIV Reverse Transcriptase; Humans; Hydrogen Bonding; Microsomes; Mutant Proteins; Pyrimidinones; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thymine | 2010 |
N1-Alkyl pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
Topics: Animals; Anti-HIV Agents; Binding Sites; Crystallography, X-Ray; Dogs; HIV Reverse Transcriptase; Humans; Microsomes; Pyrimidinones; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thymine | 2010 |
Supersonic jet UV spectrum and nonradiative processes of the thymine analogue 5-methyl-2-hydroxypyrimidine.
Topics: Pyrimidinones; Quantum Theory; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Thermodynamics; Thymine; Ultrasonics | 2010 |
Docking, molecular dynamics and quantitative structure-activity relationship studies for HEPTs and DABOs as HIV-1 reverse transcriptase inhibitors.
Topics: Amino Acids; Anti-HIV Agents; Binding Sites; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Protein Binding; Pyrimidinones; Quantitative Structure-Activity Relationship; Reverse Transcriptase Inhibitors; Thymine | 2012 |
Gas-phase hydration thermochemistry of sodiated and potassiated nucleic acid bases.
Topics: Adenine; Cytosine; Gases; Mass Spectrometry; Potassium; Pyrimidinones; Sodium; Thermodynamics; Thymine; Uracil | 2012 |
Vibrational signatures of Watson-Crick base pairing in adenine-thymine mimics.
Topics: Base Pairing; Pyrimidines; Pyrimidinones; Thymine; Vibration | 2013 |
UV-induced formation of the thymine-thymine pyrimidine (6-4) pyrimidone photoproduct--a DFT study of the oxetane intermediate ring opening.
Topics: DNA; Ethers, Cyclic; Models, Molecular; Protons; Pyrimidines; Pyrimidinones; Thermodynamics; Thymine; Ultraviolet Rays; Water | 2013 |
Synthesis of thyminyl stilbazoles and their photo-reactivity.
Topics: Alkenes; Crystallography, X-Ray; Cycloaddition Reaction; Dimerization; Molecular Conformation; Pyridines; Pyrimidinones; Thymine; Ultraviolet Rays | 2014 |
An unexpected deamination reaction after hydrolysis of the pyrimidine (6-4) pyrimidone photoproduct.
Topics: Deamination; DNA; Hydrolysis; Magnetic Resonance Spectroscopy; Pyrimidines; Pyrimidinones; Thymine | 2014 |
Crosslinking reactions of 4-amino-6-oxo-2-vinylpyrimidine with guanine derivatives and structural analysis of the adducts.
Topics: Cross-Linking Reagents; DNA; DNA Adducts; Guanine; Metals; Oligonucleotides; Pyrimidinones; RNA; Thymine; Vinyl Compounds | 2015 |
Reliable vibrational wavenumbers for C=O and N-H stretchings of isolated and hydrogen-bonded nucleic acid bases.
Topics: Adenine; Base Pairing; Cytosine; Dimerization; Guanine; Hydrogen; Hydrogen Bonding; Models, Molecular; Nitrogen; Nucleic Acids; Oxygen; Pyrimidinones; Spectrophotometry, Infrared; Thymine; Uracil | 2016 |
Model Studies on the Photoreduction of the 5-Hydroxy-5,6-dihydrothymine and 5-Methyl-2-pyrimidone Moieties of (6-4) Photoproducts by Photolyase.
Topics: Deoxyribodipyrimidine Photo-Lyase; DNA Repair; Electron Transport; Flavin-Adenine Dinucleotide; Pyrimidinones; Thymine | 2022 |