thymine has been researched along with pyrimidine in 67 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (49.25) | 18.7374 |
| 1990's | 4 (5.97) | 18.2507 |
| 2000's | 12 (17.91) | 29.6817 |
| 2010's | 16 (23.88) | 24.3611 |
| 2020's | 2 (2.99) | 2.80 |
| Authors | Studies |
|---|---|
| Kiang, DT; Mirkin, BL; O'Dea, RF; Ramnaraine, ML; Stoeckeler, JS; Tuchman, M | 1 |
| Doetsch, PW; Franklin, WA; Haseltine, WA | 1 |
| Fujii, S; Shirasaka, T | 1 |
| Patel, DJ; Radhakrishnan, I | 1 |
| Ambulos, NP; Friedberg, EC; Malanoski, G; Radany, EH; Yasbin, RE | 1 |
| Altmann, KH; Freier, SM | 1 |
| Akamo, Y; Fukui, T; Kidouchi, K; Kobayashi, K; Manabe, T; Mizuno, I; Mohri, N; Sumi, S; Takeyama, H | 1 |
| Santoso, D; Thornburg, R | 1 |
| Aukett, A; Baaske, H; Dobritzsch, D; Duley, JA; Haasjes, J; Hein, G; Kalhoff, H; Kirk, JM; Lindqvist, Y; Maropoulos, GD; Meinsma, R; Nowaczyk, MJ; van Gennip, AH; van Kuilenburg, AB; Ward, KP; Waterham, HR | 1 |
| Fukushima, M; Honda, T; Inagawa, H; Moriyama, A; Soma, G | 1 |
| Hall, KB; Jean, JM | 1 |
| Chen, YH; Huang, XL; Li, LQ; Zhang, HY | 1 |
| Au, KM; Chan, AY; Lai, CK; Lam, CW; Shek, CC; Yuen, YP | 1 |
| WYATT, GR | 1 |
| CLINE, RE; FINK, K; FINK, RM; MCGAUGHEY, C | 1 |
| ROGERS, S | 1 |
| BATT, RD | 1 |
| HALE, R; LOWDEN, L; SHAPIRA, J | 1 |
| DEYSSON, G; TRUHAUT, R | 1 |
| LANGEN, P; LISS, E | 1 |
| KALLEN, RG; MARMUR, J; SIMON, M | 1 |
| JEFFREY, JJ; SCHANKER, LS | 1 |
| MESNARD, G; VASILESCU, D | 1 |
| FEDOROV, NA; KASATKIN, IN | 1 |
| GREKH, IF; KARLINSKAIA, RS; TURBINA, IL | 1 |
| HU, PC; LIANG, CC; LIU, CP; WU, H | 1 |
| TARR, HL | 1 |
| FAGUET, M | 1 |
| CURCI, MR; DONACHI, WD | 1 |
| BERTHOD, H; PULLMAN, A | 1 |
| PULLMAN, B | 1 |
| BIGGS, H; DOUMAS, B | 1 |
| ZIMMERMAN, M | 1 |
| CAILLET, J; CLAVERIE, P; PULLMAN, B | 1 |
| CHARGAFF, E; DANON, A; RUEST, P; TEMPERLI, A; TUERLER, H | 1 |
| COOPER, EH; MILTON, JD | 1 |
| LANGEN, P | 1 |
| COHEN, PP; LINDSAY, RH; NAKAGAWA, H | 1 |
| MORSE, PA; POTTER, VR | 1 |
| LOVTRUP, S; SHUGAR, D | 1 |
| CALVIN, M; LEMMON, RM; PONNAMPERUMA, CA | 1 |
| CERECEDO, LR; PIRCIO, A | 1 |
| ALLFREY, VG; DALY, MM; MIRSKY, AE | 1 |
| Hoffmann, GF; Hofmann, U; Kohlmüller, D; Mürdter, T; Schmidt, C; Schwab, M; Zanger, UM | 1 |
| Alvarado, F; Bari, S; Bernigaud, V; Hoekstra, R; Huber, B; Lecointre, A; Manil, B; Rangama, J; Schlathölter, T | 1 |
| Hanaoka, F; Ide, H; Iwai, S; Katafuchi, A; Matsubara, M; Terato, H | 1 |
| de Bruin, M; Emura, T; Fukushima, M; Peters, GJ; Temmink, OH | 1 |
| Amzel, LM; Bianchet, MA; Friedman, JI; Krosky, DJ; Parker, JB; Stivers, JT | 1 |
| Hirao, K; Ishihama, A; Kori, A; Shimada, T; Yamamoto, K | 1 |
| Hu, P; Liang, QL; Luo, GA; Wang, YM; Xia, JF; Zou, TT | 1 |
| Nakamura, Y; Urata, H; Wada, S; Yamaguchi, E | 1 |
| Couve, S; Gasparutto, D; Ishchenko, AA; Mazouzi, A; Redrejo-Rodríguez, M; Saint-Pierre, C; Saparbaev, M | 1 |
| Basu, S; Mitra, A; Sarangi, MK | 1 |
| Cadet, J; Douki, T; Eriksson, LA; Grand, A; Jorge, N; Labet, V; Morell, C | 1 |
| Almeida, D; da Silva, FF; Denifl, S; Flosadóttir, HD; García, G; Ingólfsson, O; Limão-Vieira, P; Matias, C; Ómarsson, B; Ptasinska, S; Puschnigg, B; Scheier, P | 1 |
| Bera, PP; Lee, TJ; Materese, CK; Nuevo, M; Sandford, SA | 1 |
| Almeida, D; Bacchus-Montabonel, MC; da Silva, FF; García, G; Limão-Vieira, P | 1 |
| Bartolotti, L; Delley, B; Franzen, S; Skalski, B | 1 |
| Singh, JS | 1 |
| Jian, Y; Li, L; Lin, G; Ouyang, H | 1 |
| Aguilar, AA; Fulfer, KD; Hardy, D; Poliakoff, ED | 1 |
| Brovarets', OO; Hovorun, DM | 1 |
| Botou, M; Evangelidis, T; Frillingos, S; Lambrinidis, G; Lazou, P; Mikros, E; Papakostas, K | 1 |
| Cercola, R; Dessent, CEH; Matthews, E; Mensa-Bonsu, G; Neumark, DM | 1 |
| Sun, Z; Zhang, CY; Zhao, H; Zou, X | 1 |
| Smith, JC; Topham, CM | 1 |
| Dworkin, JP; Furukawa, Y; Glavin, DP; Koga, T; Naraoka, H; Oba, Y; Takano, Y | 1 |
1 review(s) available for thymine and pyrimidine
| Article | Year |
|---|---|
Therapeutic potential of the dual-targeted TAS-102 formulation in the treatment of gastrointestinal malignancies.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Biological Availability; Clinical Trials as Topic; Drug Combinations; Drug Delivery Systems; Drug Resistance, Neoplasm; Forecasting; Gastrointestinal Neoplasms; Humans; Pyrimidines; Pyrrolidines; Thymidine; Thymine; Trifluridine; Uracil | 2007 |
66 other study(ies) available for thymine and pyrimidine
| Article | Year |
|---|---|
Familial pyrimidinemia and pyrimidinuria associated with severe fluorouracil toxicity.
Topics: Adult; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Female; Fluorouracil; Humans; Male; Purine-Pyrimidine Metabolism, Inborn Errors; Pyrimidines; Thymine; Uracil | 1985 |
Structural determination of the ultraviolet light-induced thymine-cytosine pyrimidine-pyrimidone (6-4) photoproduct.
Topics: Cytosine; DNA; Magnetic Resonance Spectroscopy; Photochemistry; Pyrimidines; Pyrimidinones; Spectrophotometry, Atomic; Spectrophotometry, Infrared; Thymine; Ultraviolet Rays | 1985 |
[Regulation of enzyme activities involved in pyrimidine synthesis and its application to cancer chemotherapy].
Topics: Administration, Oral; Animals; Deoxyuridine; Dihydrouracil Dehydrogenase (NAD+); DNA, Neoplasm; Drug Synergism; Fluorouracil; Neoplasms, Experimental; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Pentosyltransferases; Phosphorylation; Pyrimidines; Sarcoma, Yoshida; Tegafur; Thymidine; Thymine; Uracil; Uridine | 1984 |
Solution structure of a purine.purine.pyrimidine DNA triplex containing G.GC and T.AT triples.
Topics: Adenine; Base Composition; Base Sequence; Computer Graphics; Cytosine; DNA; Guanine; Hydrogen Bonding; Macromolecular Substances; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Purines; Pyrimidines; Thymine | 1993 |
Transfection enhancement in Bacillus subtilis displays features of a novel DNA repair pathway. I: DNA base and nucleolytic specificity.
Topics: Bacillus subtilis; Bacteriophages; Base Composition; Deoxyribonuclease (Pyrimidine Dimer); DNA Glycosylases; DNA Repair; DNA, Bacterial; Endodeoxyribonucleases; Escherichia coli Proteins; N-Glycosyl Hydrolases; Pentoxyl; Pyrimidines; Substrate Specificity; Thymine; Transfection; Ultraviolet Rays; Uracil-DNA Glycosidase | 1997 |
The ups and downs of nucleic acid duplex stability: structure-stability studies on chemically-modified DNA:RNA duplexes.
Topics: DNA; Nucleic Acid Conformation; Nucleic Acid Hybridization; Oligonucleotides, Antisense; Phosphorus; Purines; Pyrimidines; Ribose; RNA, Complementary; Structure-Activity Relationship; Thymine | 1997 |
[A case of gastric cancer with decreased dihydropyrimidine dehydrogenase activity].
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Dihydrouracil Dehydrogenase (NADP); Female; Fluorouracil; Humans; Oxidoreductases; Pyrimidines; Stomach Neoplasms; Thymine; Uracil | 1998 |
Fluoroorotic acid-selected Nicotiana plumbaginifolia cell lines with a stable thymine starvation phenotype have lost the thymine-regulated transcriptional program.
Topics: Aspartate Carbamoyltransferase; Blotting, Western; Cell Line; Chromatography, Thin Layer; Dihydroorotase; Dihydroorotate Dehydrogenase; Gene Expression Regulation, Plant; Multienzyme Complexes; Nicotiana; Orotate Phosphoribosyltransferase; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Phenotype; Plants, Toxic; Pyrimidines; RNA, Messenger; Thymine | 2000 |
Novel disease-causing mutations in the dihydropyrimidine dehydrogenase gene interpreted by analysis of the three-dimensional protein structure.
Topics: Age of Onset; Amino Acids; Animals; Cells, Cultured; Child, Preschool; Crystallography, X-Ray; Dihydrouracil Dehydrogenase (NADP); Electron Transport; Exons; Fibroblasts; Fluorouracil; Gene Deletion; Genotype; Granulocytes; Humans; Infant; Infant, Newborn; Intellectual Disability; Leukocytes, Mononuclear; Models, Molecular; Motor Skills Disorders; Mutation; Mutation, Missense; Oxidoreductases; Phenotype; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Pyrimidines; Swine; Thymine; Uracil | 2002 |
Development and characterization of a monoclonal antibody with cross-reactivity towards uracil and thymine, and its potential use in screening patients treated with 5-fluorouracil for possible risks.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Contraindications; Cross Reactions; Dihydrouracil Dehydrogenase (NADP); Enzyme Inhibitors; Fluorouracil; Humans; Hybridomas; Mice; Mice, Inbred BALB C; Oxidoreductases; Pyrimidines; Risk Factors; Thymine; Uracil | 2002 |
2-Aminopurine electronic structure and fluorescence properties in DNA.
Topics: 2-Aminopurine; Dimerization; DNA; Electrons; Fluorescence Resonance Energy Transfer; Guanine; Models, Chemical; Models, Molecular; Purines; Pyrimidines; Thymine | 2002 |
[Separation and determination of purine bases and pyrimidine bases from nucleic acid hydrolysis by HPLC on BDS column].
Topics: Adenine; Chromatography, High Pressure Liquid; Cytosine; Guanine; Hypoxanthine; Nucleic Acids; Purines; Pyrimidines; Thymine; Uracil; Yeasts | 2000 |
Diagnosis of dihydropyrimidine dehydrogenase deficiency in a neonate with thymine-uraciluria.
Topics: Dihydrouracil Dehydrogenase (NADP); Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Male; Oxidoreductases; Point Mutation; Purine-Pyrimidine Metabolism, Inborn Errors; Pyrimidines; Seizures; Thymine; Uracil | 2003 |
The nucleic acids of some insect viruses.
Topics: Adenine; Cytosine; DNA; Guanine; Insect Viruses; Nucleic Acids; Purines; Pyrimidines; Thymine; Viruses | 1952 |
Metabolism of intermediate pyrimidine reduction products in vitro.
Topics: Butyrates; In Vitro Techniques; Lipid Metabolism; Liver; Pyrimidines; Thymine; Uracil | 1956 |
Studies of the mechanism of action of urethane in initiating pulmonary adenomas in mice. II. Its relation to nucleic acid synthesis.
Topics: Adenine; Adenoma; Animals; DNA; Lung Neoplasms; Mice; Neoplasms; Nucleic Acids; Orotic Acid; Pyrimidines; RNA; Thymine; Urethane | 1957 |
Induction of enzymes for pyrimidine catabolism in Nocardia corallina.
Topics: Nocardia; Oxidoreductases; Pyrimidines; Thymine; Uracil | 1961 |
Inhibition of a thymine-deficient mutant of Escherichia coli by 5-substituted uracils.
Topics: Escherichia coli; Nucleosides; Pyrimidines; Thymine; Uracil | 1962 |
[Research on the antimitotic properties of antagonists of natural pyrimidine bases. II. 6-Azauracil, 6-azathymine, 2-thio-5-methylcytosine and 4-methyl-5-bis(beta-chloroethyl)-aminouracil].
Topics: 5-Methylcytosine; Antimitotic Agents; Antineoplastic Agents; Pyrimidines; Thymine; Uracil | 1962 |
[The utilization of thymidine, bromodesoxyuridine and the free pyrimidine bases thymine, bromouracil and iodouracil in desoxyribonucleic acid synthes by ascites tumor cells in vitro].
Topics: Animals; Ascites; Bromouracil; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; In Vitro Techniques; Nucleotides; Pyrimidines; Thymidine; Thymine; Uracil; Uracil Nucleotides | 1962 |
The new occurrence of a new pyrimidine base replacing thymine in a bacteriophage DNA:5-hydroxymethyl uracil.
Topics: Bacteriophages; DNA; DNA, Viral; Pentoxyl; Pyrimidines; Thymine; Uracil | 1962 |
Structural specificity of the pyrimidine transport process of the small intestine.
Topics: Barbiturates; Cytosine; Intestine, Small; Intestines; Pyrimidines; Thiouracil; Thymine; Uracil | 1962 |
[SEMI-CONDUCTIBILITY OF DNA (DESOXYRIBONUCLEIC ACID) AND OF PURINE AND PYRIMIDINE BASES OF DNA AND RNA (RIBONUCLEIC ACID)].
Topics: Adenine; Cytosine; DNA; Electrophysiology; Guanine; Purines; Pyrimidines; Research; RNA; Thymine; Uracil | 1963 |
[ON MOBILITY OF PURINES AND PYRIMIDINE BASES AND THEIR DERIVATIVES DURING ELECTROPHORETIC SEPARATION].
Topics: Adenine; Adenine Nucleotides; Cytosine Nucleotides; Electrophoresis; Guanine; Nucleosides; Nucleotides; Purines; Pyrimidines; Research; Thymidine; Thymine; Uracil | 1964 |
[ON THE EFFECT OF CERTAIN PYRIMIDINE DERIVATIVES ON THE METASTASIZATION OF TRANSPLANTABLE SSK RAT SARCOMA].
Topics: Cytosine; Neoplasm Metastasis; Neoplasms; Pharmacology; Pyrimidines; Rats; Research; Sarcoma; Sarcoma, Experimental; Thymine | 1964 |
STUDIES ON THE ANALYSIS OF PURINE AND PYRIMIDINE BASES OF NUCLEIC ACID. III. A DIRECT SPECTROPHOTOMETRIC METHOD FOR THE ANALYSIS OF THE PURINE AND PYRIMIDINE BASES IN DNA.
Topics: Adenine; Cytosine; DNA; Guanine; Nucleic Acids; Purines; Pyrimidines; Spectrophotometry; Thymine | 1964 |
FORMATION OF RIBOMONONUCLEOTIDES FROM PURINE AND PYRIMIDINE BASES AND 5'-PHOSPHORIBOSYLPYROPHOSPHATE BY A SALMON MILT EXTRACT.
Topics: Adenine; Adenine Nucleotides; Animals; Carbon Isotopes; Chromatography; Cytosine; Cytosine Nucleotides; Diphosphates; Fishes; Guanine; Guanine Nucleotides; Metabolism; Nucleotides; Orotic Acid; Phosphoribosyl Pyrophosphate; Purines; Pyrimidines; Research; Salmon; Thymine; Tissue Extracts; Tritium; Uracil; Uracil Nucleotides; Xanthines | 1964 |
[ON THE ACTION OF CERTAIN PURINE AND PYRIMIDINE BASES ON THE INDUCTION OF LYSIS INDUCED BY IRRADIATION OF CULTURES OF LYSOGENIC ESCHERICHIA COLI BY ULTRAVIOLET RAYS AND ON SOME ELECTRONIC ASPECTS OF THIS ACTION].
Topics: Adenine; Bacteriolysis; Cytosine; Escherichia coli; Pharmacology; Purines; Pyrimidines; Radiation Effects; Research; Thymine; Ultraviolet Rays | 1964 |
AN ATTEMPT TO FIND PYRIMIDINE INHIBITORS OF A MAMMALIAN ASPARTATE CARBAMOYLTRANSFERASE.
Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Carbon Isotopes; Colorimetry; Cytosine Nucleotides; Enzyme Inhibitors; Erythrocytes; Nucleosides; Nucleotides; Pyrimidines; Rabbits; Research; Thymidine; Thymine; Tissue Extracts; Transferases; Uracil Nucleotides | 1964 |
[INFLUENCE OF THE HYDROGEN BOND ON THE DIPOLAR MOMENT OF PURINE-PYRIMIDINE PAIRS OF NUCLEIC ACIDS].
Topics: Acetates; Adenine; Amines; Biochemical Phenomena; Biochemistry; Cytosine; Guanine; Hydrogen; Nucleic Acids; Purines; Pyridines; Pyrimidines; Research; Thymine | 1964 |
[ON THE SEMI-CONDUCTIVITY OF PURINE AND PYRIMIDINE BASES OF NUCLEIC ACIDS].
Topics: Adenine; Chemical Phenomena; Chemistry, Physical; Cytosine; Guanine; Nucleic Acids; Purines; Pyrimidines; Research; Thymine; Uracil | 1964 |
PYRIMIDINE INCORPORATION INTO NUCLEIC ACIDS OF CORYNEBACTERIA SPP.
Topics: Corynebacterium; DNA; DNA, Bacterial; Nucleic Acids; Orotic Acid; Proteins; Pyrimidines; Research; RNA; RNA, Bacterial; Thymine; Uracil | 1964 |
DEOXYRIBOSYL TRANSFER. II. NUCLEOSIDE:PYRIMIDINE DEOXYRIBOSYLTRANSFERASE ACTIVITY OF THREE PARTIALLY PURIFIED THYMIDINE PHOSPHORYLASES.
Topics: Escherichia coli; Glucosyltransferases; Hot Temperature; Hydrogen-Ion Concentration; Liver; Nucleosides; Pyrimidines; Rats; Research; Ribose; Spleen; Thymidine Phosphorylase; Thymine; Urea | 1964 |
INTERMOLECULAR FORCES IN ASSOCIATION OF PURINES WITH POLYBENZENOID HYDROCARBONS.
Topics: Adenine; Benzopyrenes; Caffeine; Chemical Phenomena; Chemistry; Cytosine; Guanine; Hypoxanthines; London; Purines; Pyrimidines; Research; Thymine; Uracil; Uric Acid; Xanthines | 1965 |
STUDIES OF THE NUCLEOTIDE ARRANGEMENT IN DEOXYRIBONUCLEIC ACIDS. IX. SELECTIVE DEGRADATION OF PYRIMIDINE DEOXYRIBONUCLEOTIDES.
Topics: Chemical Phenomena; Chemistry; Cytosine; Deoxyribonucleotides; DNA; Hydrazines; Kinetics; Nucleotides; Pyrazoles; Pyrimidines; Research; Thymine; Urea | 1964 |
THE INCORPORATION AND DEGRADATION OF PYRIMIDINE DNA PRECURSORS BY HUMAN LEUCOCYTES.
Topics: Autoradiography; Carbon Isotopes; Cytosine Nucleotides; Deoxyuridine; DNA; Humans; Infectious Mononucleosis; Leukemia; Leukemia, Myeloid; Leukocytes; Metabolism; Pyrimidines; Thymidine; Thymine; Tritium; Uracil | 1964 |
INFLUENCE OF PURINE AND PYRIMIDINE COMPOUNDS ON DNA-SYNTHESIS OF ASCITES-TUMOUR CELLS.
Topics: Animals; Ascites; Carcinoma, Ehrlich Tumor; Cytosine Nucleotides; DNA; DNA, Neoplasm; Fluorouracil; Metabolism; Neoplasms, Experimental; Nucleotides; Pharmacology; Phosphorus Isotopes; Purines; Pyrimidines; Research; Thymine; Uracil; Uracil Nucleotides | 1964 |
THIOURACIL-PYRIMIDINE RELATIONSHIPS IN THYROID AND OTHER TISSUES.
Topics: Animals; Carbon Dioxide; Carbon Isotopes; Cattle; Liver; Metabolism; Organ Size; Orotic Acid; Pharmacology; Pyrimidines; Rats; Research; RNA; Thiouracil; Thymine; Thymus Gland; Thyroid Gland; Uracil; Uracil Nucleotides | 1965 |
PYRIMIDINE METABOLISM IN TISSUE CULTURE CELLS DERIVED FROM RAT HEPATOMAS. I. SUSPENSION CELL CULTURES DERIVED FROM THE NOVIKOFF HEPATOMA.
Topics: Animals; Carcinoma, Hepatocellular; Cell Culture Techniques; Floxuridine; Fluorouracil; Glycine; Liver Neoplasms; Liver Neoplasms, Experimental; Metabolism; Methotrexate; Mutation; Neoplasms; Neoplasms, Experimental; Nucleosides; Pharmacology; Pyrimidines; Rats; Research; Serine; Thymidine; Thymidine Kinase; Thymine; Tissue Culture Techniques; Toxicology; Uracil | 1965 |
Utilization of pyrimidines and pyrimidine deoxynucleosides by Thermobacterium acidophilum (Lactobacillus acidophilus).
Topics: Lactobacillus; Lactobacillus acidophilus; Nucleosides; Nucleotides; Pentosyltransferases; Pyrimidines; Sweden; Thymidine; Thymine; Uracil | 1961 |
Chemical effect of ionizing radiation on cytosine.
Topics: Cytosine; Pyrimidines; Radiation Effects; Radiation, Ionizing; Thymine; Uracil | 1962 |
Colorimetric determination of the pyrimidine content of the desoxyribonucleic acids of thymus and fish sperm.
Topics: Animals; DNA; Male; Nucleic Acids; Pyrimidines; Spermatozoa; Thymine | 1950 |
Purine and pyrimidine contents of some desoxypentose nucleic acids.
Topics: Adenine; Animals; Cattle; Cytosine; Guanine; Horses; Nucleic Acids; Purines; Pyrimidines; Sheep; Thymine | 1950 |
Comprehensive analysis of pyrimidine metabolism in 450 children with unspecific neurological symptoms using high-pressure liquid chromatography-electrospray ionization tandem mass spectrometry.
Topics: Adolescent; beta-Alanine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Dihydropyrimidine Dehydrogenase Deficiency; Dihydrouracil Dehydrogenase (NADP); Epilepsy; Exons; Female; Genotype; Humans; Infant; Infant, Newborn; Ions; Male; Mass Spectrometry; Models, Statistical; Mutation; Normal Distribution; Ornithine Carbamoyltransferase Deficiency Disease; Pyrimidines; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Thymine; Uracil | 2005 |
Ion-induced biomolecular radiation damage: from isolated nucleobases to nucleobase clusters.
Topics: Adenine; Base Composition; Biophysics; Chemistry, Physical; DNA; Electrons; Hydrogen Bonding; Ions; Mass Spectrometry; Molecular Conformation; Purines; Pyrimidines; Spectrophotometry; Thymine; Uracil | 2006 |
Damage specificity of human DNA glycosylases for oxidative pyrimidine lesions.
Topics: DNA Damage; DNA Glycosylases; HeLa Cells; Humans; Oxidation-Reduction; Pyrimidines; Solutions; Stereoisomerism; Substrate Specificity; Thymine | 2004 |
Enzymatic capture of an extrahelical thymine in the search for uracil in DNA.
Topics: Base Pairing; Binding Sites; DNA; DNA Damage; DNA Repair; Escherichia coli; Humans; Models, Molecular; Mutant Proteins; Nucleic Acid Conformation; Protein Conformation; Protons; Pyrimidines; Substrate Specificity; Thymine; Uracil; Uracil-DNA Glycosidase | 2007 |
RutR is the uracil/thymine-sensing master regulator of a set of genes for synthesis and degradation of pyrimidines.
Topics: Allantoin; Aptamers, Nucleotide; Base Sequence; Binding Sites; Blotting, Northern; Deoxyribonuclease I; DNA Footprinting; Electrophoretic Mobility Shift Assay; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Glutamic Acid; Models, Biological; Mutation; Promoter Regions, Genetic; Protein Binding; Pyrimidines; SELEX Aptamer Technique; Thymine; Transcription Factors; Uracil | 2007 |
Correlations of creatine and six related pyrimidine metabolites and diabetic nephropathy in Chinese type 2 diabetic patients.
Topics: Aged; Chromatography, High Pressure Liquid; Creatine; Cytidine; Cytosine; Deoxyuridine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Male; Middle Aged; Pyrimidines; Tandem Mass Spectrometry; Thymidine; Thymine; Uridine | 2010 |
Pyrimidine-pyrimidine base pairs stabilized by silver(I) ions.
Topics: 5-Methylcytosine; Base Pair Mismatch; Base Pairing; Cytosine; Hydrogen Bonding; Ions; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Pyrimidines; Silver; Thymine | 2011 |
New insights in the removal of the hydantoins, oxidation product of pyrimidines, via the base excision and nucleotide incision repair pathways.
Topics: Base Sequence; DNA; DNA Glycosylases; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; HeLa Cells; Humans; Hydantoins; Kinetics; Oligodeoxyribonucleotides; Oxidation-Reduction; Pyrimidines; Thymine; Urea | 2011 |
Prototropic interactions of pyrimidine nucleic acid bases with acridine: a spectroscopic investigation.
Topics: Acridines; Cytosine; Electron Transport; Lasers; Pyrimidines; Spectrum Analysis; Thymine; Uracil | 2012 |
UV-induced formation of the thymine-thymine pyrimidine (6-4) pyrimidone photoproduct--a DFT study of the oxetane intermediate ring opening.
Topics: DNA; Ethers, Cyclic; Models, Molecular; Protons; Pyrimidines; Pyrimidinones; Thermodynamics; Thymine; Ultraviolet Rays; Water | 2013 |
NCO(-), a key fragment upon dissociative electron attachment and electron transfer to pyrimidine bases: site selectivity for a slow decay process.
Topics: Anions; Cyanates; Electrons; Ions; Pyrimidines; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thymine | 2013 |
Thymine and other prebiotic molecules produced from the ultraviolet photo-irradiation of pyrimidine in simple astrophysical ice analogs.
Topics: Chromatography, High Pressure Liquid; Extraterrestrial Environment; Gas Chromatography-Mass Spectrometry; Ice; Methane; Methanol; Pyrimidines; Reference Standards; Thymine; Ultraviolet Rays; Water | 2013 |
Potassium-uracil/thymine ring cleavage enhancement as studied in electron transfer experiments and theoretical calculations.
Topics: DNA; Electron Transport; Potassium; Pyrimidines; Quantum Theory; RNA; Thymine; Uracil | 2014 |
The coupling of tautomerization to hydration in the transition state on the pyrimidine photohydration reaction path.
Topics: Cytosine; Pyrimidines; Quantum Theory; Thermodynamics; Thymine; Uridine; Water | 2014 |
FT-IR and Raman spectra, ab initio and density functional computations of the vibrational spectra, molecular geometries and atomic charges of uracil and 5-methyluracil (thymine).
Topics: Hydrogen; Hydrogen Bonding; Molecular Conformation; Normal Distribution; Pyrimidines; Quantum Theory; Software; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Temperature; Thymine; Uracil; Vibration | 2015 |
An unexpected deamination reaction after hydrolysis of the pyrimidine (6-4) pyrimidone photoproduct.
Topics: Deamination; DNA; Hydrolysis; Magnetic Resonance Spectroscopy; Pyrimidines; Pyrimidinones; Thymine | 2014 |
High-resolution photoelectron spectra of the pyrimidine-type nucleobases.
Topics: Cytosine; Electrons; Gases; Ions; Photochemistry; Photons; Pyrimidines; Thymine; Uracil | 2015 |
A novel conception for spontaneous transversions caused by homo-pyrimidine DNA mismatches: a QM/QTAIM highlight.
Topics: Base Pair Mismatch; Cytosine; DNA; Hydrogen Bonding; Pyrimidines; Quantum Theory; Thermodynamics; Thymine | 2015 |
Insight on specificity of uracil permeases of the NAT/NCS2 family from analysis of the transporter encoded in the pyrimidine utilization operon of Escherichia coli.
Topics: Bacteria; Escherichia coli; Escherichia coli Proteins; Membrane Transport Proteins; Molecular Docking Simulation; Multigene Family; Operon; Phylogeny; Pyrimidines; Substrate Specificity; Thymine; Uracil | 2018 |
Photoexcitation of iodide ion-pyrimidine clusters above the electron detachment threshold: Intracluster electron transfer versus nucleobase-centred excitations.
Topics: Cytosine; Electron Transport; Electrons; Iodides; Ions; Photochemical Processes; Pyrimidines; Quantum Theory; Thymine | 2018 |
Mechanistic insight into photocrosslinking reaction between triplet state 4-thiopyrimidine and thymine.
Topics: Computer Simulation; Cross-Linking Reagents; Density Functional Theory; Light; Molecular Structure; Photochemical Processes; Pyrimidines; Thermodynamics; Thymine | 2019 |
Peptide nucleic acid Hoogsteen strand linker design for major groove recognition of DNA thymine bases.
Topics: Alanine; Alkenes; Base Pairing; Cross-Linking Reagents; Crystallography, X-Ray; DNA; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Nucleic Acid Conformation; Peptide Nucleic Acids; Peptides; Pyrimidines; RNA, Untranslated; Thermodynamics; Thymine | 2021 |
Identifying the wide diversity of extraterrestrial purine and pyrimidine nucleobases in carbonaceous meteorites.
Topics: Meteoroids; Purines; Pyrimidines; Thymine | 2022 |