thymine and organophosphonates

thymine has been researched along with organophosphonates in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's2 (18.18)18.2507
2000's6 (54.55)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brown, DM; Lin, PK1
Abushanab, E; El-Subbagh, HI; Panzica, RP; Racha, S; Vargeese, C; Vemishetti, P1
Graczyk, J; Ochocki, J1
Gross, ML; Wan, KX1
Holý, A; Otová, B; Pomeisl, K; Tloust'ová, E; Votruba, I1
Beadle, JR; Chong, Y; Choo, H; Hostetler, KY; Trahan, J1
Holý, A; Pohl, R; Pomeisl, K; Votruba, I1
Holý, A; Pomeisl, K; Votruba, I1
Herdewijn, P; Huang, Q1
Blažek, J; Horská, K; Krečmerová, M; Pohl, R; Pomeisl, K1
Hocková, D; Ménová, P; Novák, P; Páv, O; Pohl, R; Rosenberg, I; Rosenbergová, Š1

Other Studies

11 other study(ies) available for thymine and organophosphonates

ArticleYear
Synthesis and duplex stability of oligonucleotides containing cytosine-thymine analogues.
    Nucleic acids research, 1989, Dec-25, Volume: 17, Issue:24

    Topics: Amides; Base Composition; Base Sequence; Chemical Phenomena; Chemistry; Cytosine; Molecular Sequence Data; Molecular Structure; Organophosphonates; Oxazines; Phosphoric Acids; Polynucleotides; Pyrimidines; Thymine

1989
Synthesis and biological evaluation of1',2'-seconucleo-5'- phosphonates.
    Journal of medicinal chemistry, 1996, Mar-01, Volume: 39, Issue:5

    Topics: Adenine; Adenoviruses, Human; Antiviral Agents; Cystine; HIV; Molecular Structure; Nucleotides; Organophosphonates; Organophosphorus Compounds; RNA Viruses; Thymine; Uracil

1996
Investigations on the influence of cisplatin on the antitumor effect of novel phosphonate derivatives of uracil and thymine.
    Die Pharmazie, 1998, Volume: 53, Issue:12

    Topics: Animals; Antineoplastic Agents; Cisplatin; Drug Interactions; Leukemia L1210; Male; Mice; Organophosphonates; Thymine; Tumor Cells, Cultured; Uracil

1998
Fragmentation mechanisms of oligodeoxynucleotides: effects of replacing phosphates with methylphosphonates and thymines with other bases in T-rich sequences.
    Journal of the American Society for Mass Spectrometry, 2001, Volume: 12, Issue:5

    Topics: Isomerism; Models, Molecular; Molecular Structure; Oligodeoxyribonucleotides; Organophosphonates; Phosphates; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship; Thymine

2001
Inhibition of thymidine phosphorylase (PD-ECGF) from SD-lymphoma by phosphonomethoxyalkyl thymines.
    Biochemical pharmacology, 2005, May-15, Volume: 69, Issue:10

    Topics: Animals; Enzyme Inhibitors; Lymphoma, T-Cell; Organophosphonates; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship; Thymidine Phosphorylase; Thymine; Thymopoietins

2005
Synthesis of the 5-phosphono-pent-2-en-1-yl nucleosides: a new class of antiviral acyclic nucleoside phosphonates.
    Bioorganic & medicinal chemistry, 2007, Feb-15, Volume: 15, Issue:4

    Topics: Antiviral Agents; Herpesvirus 1, Human; Humans; Inhibitory Concentration 50; Nucleosides; Organophosphonates; Thymine

2007
Syntheses of N3-substituted thymine acyclic nucleoside phosphonates and a comparison of their inhibitory effect towards thymidine phosphorylase.
    Bioorganic & medicinal chemistry letters, 2008, Feb-15, Volume: 18, Issue:4

    Topics: Animals; Cricetinae; Cricetulus; Enzyme Inhibitors; Humans; Lymphoma, T-Cell; Organophosphonates; Placenta; Pyrimidine Nucleosides; Rats; Structure-Activity Relationship; Thymidine Phosphorylase; Thymine

2008
Pyrimidine acyclic nucleoside phosphonates and phosphorylated analogs. Part 2. Syntheses and investigation of their inhibitory effects towards human thymidine phosphorylase.
    Nucleic acids symposium series (2004), 2008, Issue:52

    Topics: Antineoplastic Agents; Enzyme Inhibitors; Humans; Organophosphonates; Phosphorylation; Thymidine Phosphorylase; Thymine

2008
Synthesis of 3'-o-phosphonoethyl nucleosides with an adenine and a thymine base moiety.
    Nucleosides, nucleotides & nucleic acids, 2009, Volume: 28, Issue:5

    Topics: Adenine; Antiviral Agents; Cell Line; Cell Survival; Hepacivirus; HIV; Humans; Microbial Sensitivity Tests; Nucleosides; Organophosphonates; Thymine

2009
Syntheses of 1-[2-(Phosphonomethoxy)Alkyl] thymine monophosphates and an evaluation of their inhibitory activity toward human thymidine phosphorylase.
    Nucleosides, nucleotides & nucleic acids, 2012, Volume: 31, Issue:3

    Topics: Animals; Cricetinae; Cricetulus; Humans; Kinetics; Molecular Structure; Organophosphonates; Phosphates; Phosphorylation; Thymidine; Thymidine Phosphorylase; Thymine

2012
N-Branched acyclic nucleoside phosphonates as monomers for the synthesis of modified oligonucleotides.
    Organic & biomolecular chemistry, 2015, Apr-21, Volume: 13, Issue:15

    Topics: Adenine; Base Sequence; DNA-Directed DNA Polymerase; Humans; Nucleic Acid Synthesis Inhibitors; Nucleosides; Oligonucleotides; Organophosphonates; Thymine

2015