thymine has been researched along with o-4-methylthymine in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (27.78) | 18.7374 |
| 1990's | 23 (63.89) | 18.2507 |
| 2000's | 2 (5.56) | 29.6817 |
| 2010's | 1 (2.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eberle, G; Huh, NH; Kang, HI; Konishi, C; Kuroki, T; Rajewsky, MF | 1 |
| Dosanjh, MK; Essigmann, JM; Samson, L; Sassanfar, M | 1 |
| Anderson, MW; Belinsky, SA; Devereux, TR | 1 |
| Essigmann, JM; Singer, B | 1 |
| Dosanjh, MK; Essigmann, JM; Goodman, MF; Singer, B | 1 |
| Martel-Planche, G; Mironov, NM; Montesano, R; Swann, PF; Wild, CP | 1 |
| Cawkwell, L; Georgiadis, P; Margison, GP; Patel, D; Potter, PM; Swann, PF; Wilkinson, MC | 1 |
| Bromley, M; Fan, CY; Fida, S; O'Connor, PJ; Saffhill, R | 1 |
| Graves, RJ; Li, BF; Swann, PF | 1 |
| Loeb, LA; Preston, BD; Singer, B | 1 |
| Dolan, ME; Morimoto, K; Pegg, AE; Scicchitano, D | 1 |
| Kalnik, M; Li, BF; Patel, DJ; Swann, PF | 1 |
| Day, RS; Fornace, AJ; Yarosh, DB | 1 |
| Karran, P; Lindahl, T; McCarthy, TV | 1 |
| Dolan, ME; Pegg, AE; Scicchitano, D; Singer, B | 1 |
| Menichini, P; Mroczkowska, MM; Singer, B | 1 |
| Ihara, K; Kawate, H; Kohda, K; Sakumi, K; Sekiguchi, M | 1 |
| Day, RS; Xu, YZ | 1 |
| Huh, N; Kang, H; Konishi, C; Kuroki, T | 2 |
| Bleeker, MJ; Brugghe, HF; Klein, JC; Kriek, E; Margison, GP; Rafferty, JA; Roelen, HC; van Boom, JH; van den Elst, H; van der Marel, GA | 1 |
| Cruzeiro-Hansson, L; Goodfellow, JM | 1 |
| Cruzeiro-Hansson, L; Goodfellow, JM; Umrania, Y | 1 |
| Kleibl, K; Laval, F; Zak, P | 1 |
| Dosanjh, MK; Eritja, R; Menichini, P; Singer, B | 1 |
| Harris, LC; Margison, GP | 1 |
| Drummond, JT; Duckett, DR; Lilley, DM; Modrich, P; Murchie, AI; Reardon, JT; Sancar, A | 1 |
| Chenna, A; Rao, S; Singer, B; Slupska, M | 1 |
| Altshuler, KB; Essigmann, JM; Hodes, CS | 1 |
| Clarke, ND; Paalman, SR; Sung, C | 1 |
| Hughes, SH; Moschel, RC; Pauly, GT | 1 |
| Kooistra, R; Lohman, PH; Margison, GP; Pastink, A; Watson, AJ; Zonneveld, JB | 1 |
| Encell, LP; Loeb, LA | 2 |
| Moschel, RC; Pauly, GT | 1 |
| Duncan Lyngdoh, RH; Premila Devi, S; Salam, T | 1 |
1 review(s) available for thymine and o-4-methylthymine
| Article | Year |
|---|---|
Site-specific mutagenesis: retrospective and prospective.
Topics: Animals; DNA; DNA Damage; Guanine; Humans; Mutagenesis; Neoplasms; Thymine | 1991 |
35 other study(ies) available for thymine and o-4-methylthymine
| Article | Year |
|---|---|
Highly sensitive, specific detection of O6-methylguanine, O4-methylthymine, and O4-ethylthymine by the combination of high-performance liquid chromatography prefractionation, 32P postlabeling, and immunoprecipitation.
Topics: Chromatography, High Pressure Liquid; DNA; Guanosine; Humans; Hydrolysis; Isotope Labeling; Leukocytes; Liver; Phosphorus Radioisotopes; Precipitin Tests; Sensitivity and Specificity; Thymine; Time Factors | 1992 |
Relative efficiencies of the bacterial, yeast, and human DNA methyltransferases for the repair of O6-methylguanine and O4-methylthymine. Suggestive evidence for O4-methylthymine repair by eukaryotic methyltransferases.
Topics: Base Sequence; Carcinogens; DNA Damage; DNA Repair; Escherichia coli; Guanine; Humans; Methyltransferases; Molecular Sequence Data; Mutagens; O(6)-Methylguanine-DNA Methyltransferase; Saccharomyces cerevisiae; Thymine | 1991 |
Role of ras protooncogene activation in the formation of spontaneous and nitrosamine-induced lung tumors in the resistant C3H mouse.
Topics: Animals; Base Sequence; Codon; Dimethylnitrosamine; DNA; Drug Resistance; Gene Expression Regulation, Neoplastic; Genes, ras; Guanine; Incidence; Lung Neoplasms; Male; Mice; Mice, Inbred C3H; Molecular Sequence Data; Mutation; Nitrosamines; Proto-Oncogenes; Thymine; Time Factors | 1991 |
Comparative efficiency of forming m4T.G versus m4T.A base pairs at a unique site by use of Escherichia coli DNA polymerase I (Klenow fragment) and Drosophila melanogaster polymerase alpha-primase complex.
Topics: Animals; Base Composition; Base Sequence; DNA Polymerase I; DNA Primase; Drosophila melanogaster; Escherichia coli; Kinetics; Molecular Sequence Data; Oligodeoxyribonucleotides; Polydeoxyribonucleotides; RNA Nucleotidyltransferases; Thymine | 1990 |
Measurement of the removal of O6-methylguanine and O4-methylthymine from oligodeoxynucleotides using an immunoprecipitation technique.
Topics: Animals; Antibodies, Monoclonal; Base Sequence; Chromatography, High Pressure Liquid; Guanine; Humans; Male; Methyltransferases; Molecular Sequence Data; O(6)-Methylguanine-DNA Methyltransferase; Oligodeoxyribonucleotides; Precipitin Tests; Rats; Thymine | 1989 |
Purification of the E. coli ogt gene product to homogeneity and its rate of action on O6-methylguanine, O6-ethylguanine and O4-methylthymine in dodecadeoxyribonucleotides.
Topics: Alkylating Agents; Amino Acids; Chromatography, High Pressure Liquid; Deoxyribonucleotides; DNA Repair; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Expression; Genes, Bacterial; Guanine; Methylation; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Thymine | 1989 |
Phenobarbital: a non-genotoxic agent which induces the repair of O6-methylguanine from hepatic DNA.
Topics: 2-Acetylaminofluorene; Animals; DNA Repair; Guanine; Liver; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Phenobarbital; Rats; Thymine | 1988 |
Repair of synthetic oligonucleotides containing O6-methylguanine, O6-ethylguanine and O4-methylthymine, by O6-alkylguanine-DNA alkyltransferase.
Topics: Animals; Chromatography, High Pressure Liquid; DNA Repair; Escherichia coli; Guanine; Kinetics; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Thymine | 1987 |
Mutagenic potential of O4-methylthymine in vivo determined by an enzymatic approach to site-specific mutagenesis.
Topics: Base Sequence; DNA; DNA Replication; DNA-Directed DNA Polymerase; Mutagens; Mutation; Thymine; Thymine Nucleotides; Transfection | 1986 |
Specificity of O6-alkylguanine-DNA alkyltransferase.
Topics: Alkylation; Animals; Cattle; DNA Repair; Guanine; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Oligodeoxyribonucleotides; RNA, Ribosomal; RNA, Transfer; Substrate Specificity; Thymine | 1987 |
Synthesis and structural studies by nuclear magnetic resonance of dodecadeoxynucleotides containing O6-methylguanine, O6-ethylguanine and O4-methylthymine.
Topics: Guanine; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Thymine | 1987 |
Human O6-alkylguanine-DNA alkyltransferase fails to repair O4-methylthymine and methyl phosphotriesters in DNA as efficiently as does the alkyltransferase from Escherichia coli.
Topics: Alkylation; Cell Line; Cells, Cultured; Colonic Neoplasms; DNA Repair; Escherichia coli; HeLa Cells; Humans; Kinetics; Liver; Liver Neoplasms; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Poly A; Poly T; Species Specificity; Thymine | 1985 |
Inducible repair of O-alkylated DNA pyrimidines in Escherichia coli.
Topics: Alkylating Agents; Cytosine; DNA Glycosylases; DNA Repair; Escherichia coli; Methylation; Methyltransferases; N-Glycosyl Hydrolases; O(6)-Methylguanine-DNA Methyltransferase; Pyrimidines; Thymine | 1984 |
Comparison of repair of methylated pyrimidines in poly(dT) by extracts from rat liver and Escherichia coli.
Topics: Animals; DNA Repair; Escherichia coli; Guanine; Liver; Methylation; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Poly T; Polydeoxyribonucleotides; Rats; Thymine | 1984 |
Enzyme-dependent pausing during in vitro replication of O4-methylthymine in a defined oligonucleotide sequence.
Topics: Base Sequence; DNA Replication; DNA-Directed DNA Polymerase; Kinetics; Molecular Sequence Data; Mutation; Oligodeoxyribonucleotides; Thymine | 1994 |
Mouse methyltransferase for repair of O6-methylguanine and O4-methylthymine in DNA.
Topics: 3T3 Cells; Animals; Base Sequence; DNA Repair; DNA, Complementary; Guanine; HeLa Cells; Humans; Immunoblotting; Intracellular Fluid; Methylnitronitrosoguanidine; Methyltransferases; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Substrate Specificity; Thymine | 1995 |
Incision at diaminopurine: thymine base pairs but not at guanine:O4-methylthymine base pairs in DNA by extracts of human cells.
Topics: 2-Aminopurine; Base Composition; Base Sequence; Cell Line; Cell-Free System; DNA; Glioma; Guanine; Humans; Hydrogen Bonding; Molecular Sequence Data; Oligodeoxyribonucleotides; Thymine; Tumor Cells, Cultured | 1995 |
Detection of O6-methylguanine, O4-methylthymine and O4-ethylthymine in human liver and peripheral blood leukocyte DNA.
Topics: Adolescent; Adult; Aged; Autopsy; DNA; DNA Adducts; Female; Guanine; Humans; Leukocytes; Liver; Male; Middle Aged; Thymine | 1995 |
Role of nucleotide excision repair in processing of O4-alkylthymines in human cells.
Topics: Alkyl and Aryl Transferases; Base Sequence; DNA Repair; DNA Replication; Fibroblasts; HeLa Cells; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmids; Simian virus 40; Thymine; Transfection; Transferases; Xeroderma Pigmentosum | 1994 |
Flexibility and curvature of DNA duplexes containing O4-methylthymine: implications for DNA repair.
Topics: Alkylation; Base Sequence; DNA; DNA Repair; Hydrogen Bonding; Molecular Sequence Data; Nucleic Acid Conformation; Thymine | 1994 |
Adenine.methylthymine base-pairs enhance non-uniformity in DNA helices.
Topics: Adenine; Algorithms; Base Composition; Base Sequence; DNA; Methylation; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Thymine | 1994 |
Repair of O6-methylguanine and O4-methylthymine by the human and rat O6-methylguanine-DNA methyltransferases.
Topics: Animals; DNA; DNA Repair; Electrophoresis, Polyacrylamide Gel; Guanine; Humans; Kinetics; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Rats; Thymine | 1994 |
A highly sensitive and specific method for quantitation of O-alkylated DNA adducts and its application to the analysis of human tissue DNA.
Topics: Alkylating Agents; Alkylation; Chromatography, High Pressure Liquid; DNA; DNA Damage; Guanine; Humans; Leukocytes; Phosphorus Radioisotopes; Precipitin Tests; Sensitivity and Specificity; Thymine | 1993 |
Both O4-methylthymine and O4-ethylthymine preferentially form alkyl T.G pairs that do not block in vitro replication in a defined sequence.
Topics: Adenosine Triphosphate; Base Composition; Base Sequence; Deoxyguanine Nucleotides; DNA Replication; Guanine; Molecular Sequence Data; Oligonucleotide Probes; Thymine | 1993 |
Expression in mammalian cells of the Escherichia coli O6 alkylguanine-DNA-alkyltransferase gene ogt reduces the toxicity of alkylnitrosoureas.
Topics: Animals; Bacterial Proteins; Base Sequence; Cell Survival; Clone Cells; Cricetinae; Drug Resistance; Escherichia coli; Fibroblasts; Gene Expression; Guanine; Lung; Methyltransferases; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Thymine; Transfection | 1993 |
Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct.
Topics: Adenosine Triphosphatases; Bacterial Proteins; Base Composition; Base Sequence; Cisplatin; Dinucleoside Phosphates; DNA; DNA Damage; DNA Repair; DNA-Binding Proteins; Escherichia coli Proteins; Guanine; Humans; Molecular Sequence Data; MutS DNA Mismatch-Binding Protein; Protein Binding; Thymine | 1996 |
Replication of O4-methylthymine-containing oligonucleotides: effect of 3' and 5' flanking bases on formation and extension of O4-methylthymine . guanine basepairs.
Topics: Autoradiography; DNA; DNA Polymerase I; DNA-Directed DNA Polymerase; HIV Reverse Transcriptase; Nucleotides; Oligonucleotides; Thymine; Time Factors | 1996 |
Intrachromosomal probes for mutagenesis by alkylated DNA bases replicated in mammalian cells: a comparison of the mutagenicities of O4-methylthymine and O6-methylguanine in cells with different DNA repair backgrounds.
Topics: Animals; CHO Cells; Cricetinae; DNA; DNA Repair; Genetic Markers; Genetic Vectors; Guanine; Methyltransferases; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Sequence Analysis; Thymine; Transfection | 1996 |
Specificity of DNA repair methyltransferases determined by competitive inactivation with oligonucleotide substrates: evidence that Escherichia coli Ada repairs O6-methylguanine and O4-methylthymine with similar efficiency.
Topics: Bacterial Proteins; Binding, Competitive; Cloning, Molecular; DNA Repair; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Gene Expression; Guanine; Humans; Methyltransferases; O(6)-Methylguanine-DNA Methyltransferase; Peptide Fragments; Thymine; Transcription Factors | 1997 |
Comparison of mutagenesis by O6-methyl- and O6-ethylguanine and O4-methylthymine in Escherichia coli using double-stranded and gapped plasmids.
Topics: DNA Methylation; DNA Repair; Escherichia coli; Guanine; Mutagenesis; Mutagens; O(6)-Methylguanine-DNA Methyltransferase; Plasmids; Thymine | 1998 |
Identification and characterisation of the Drosophila melanogaster O6-alkylguanine-DNA alkyltransferase cDNA.
Topics: Amino Acid Sequence; Animals; Bacterial Proteins; Base Sequence; Cloning, Molecular; DNA Repair; DNA, Complementary; Drosophila melanogaster; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Guanine; Humans; Methylnitronitrosoguanidine; Methyltransferases; Molecular Sequence Data; O(6)-Methylguanine-DNA Methyltransferase; Phenotype; Thymine; Transcription Factors | 1999 |
Redesigning the substrate specificity of human O(6)-alkylguanine-DNA alkyltransferase. Mutants with enhanced repair of O(4)-methylthymine.
Topics: Amino Acid Substitution; Binding, Competitive; Cloning, Molecular; DNA Repair; Escherichia coli; Gene Expression Regulation, Bacterial; Humans; Kinetics; Mutagenesis, Site-Directed; O(6)-Methylguanine-DNA Methyltransferase; Oligonucleotides; Protein Engineering; Subcellular Fractions; Substrate Specificity; Thymine | 1999 |
Enhanced in vivo repair of O(4)-methylthymine by a mutant human DNA alkyltransferase.
Topics: DNA Damage; DNA Repair; Enzyme Inhibitors; Escherichia coli; Guanine; Humans; Lac Operon; Methylnitronitrosoguanidine; O(6)-Methylguanine-DNA Methyltransferase; Phenotype; Point Mutation; Substrate Specificity; Thymine | 2000 |
Mutagenesis by O(6)-methyl-, O(6)-ethyl-, and O(6)-benzylguanine and O(4)-methylthymine in human cells: effects of O(6)-alkylguanine-DNA alkyltransferase and mismatch repair.
Topics: Base Pair Mismatch; Colonic Neoplasms; Escherichia coli; Genetic Vectors; Guanine; Humans; Kidney; Lac Operon; Mutagenesis; Mutagens; O(6)-Methylguanine-DNA Methyltransferase; Thymine; Transfection | 2001 |
Molecular criteria for mutagenesis by DNA methylation: Some computational elucidations.
Topics: Alkylating Agents; Base Pairing; Computational Biology; DNA; DNA Methylation; Guanine; Nucleic Acid Conformation; Thymine | 2018 |