thymine has been researched along with methotrexate in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 31 (86.11) | 18.7374 |
| 1990's | 1 (2.78) | 18.2507 |
| 2000's | 2 (5.56) | 29.6817 |
| 2010's | 1 (2.78) | 24.3611 |
| 2020's | 1 (2.78) | 2.80 |
| Authors | Studies |
|---|---|
| Friedman, MA; Sadée, W | 1 |
| Johnson, B; Westergaard, O | 1 |
| Greenberg, ML; Waxman, S | 1 |
| Langley, D; Pritchard, MA; Rittenberg, S | 1 |
| Andersson, BS; Dreizen, S; Keating, MJ; McCredie, KB | 1 |
| Bleile, BM; Dickey, LM; Goulian, M; Grafstrom, RH; Ingraham, HA; Neynaber, SA; Peterson, MS; Tseng, BY | 1 |
| Lutsiuk, MB | 1 |
| Houlihan, RB; Roby, R; Teskey, C | 1 |
| Grossowicz, N; Mandelbaum-Shavit, F | 1 |
| Boisseau, M; Labatut, M; Moreau, F; Roulaud, F | 1 |
| Potter, VR; Sneider, TW | 1 |
| Sneider, TW | 1 |
| Hutchison, DJ; Mehta, BM | 1 |
| de Waard, H | 1 |
| Albrecht, AM; Hutchison, DJ; Suling, WJ | 1 |
| Farmer, JL; Rothman, F; Wilson, MC | 1 |
| Hitchings, GH | 1 |
| Doctor, VM | 1 |
| Fischer, HU; Jobski, C; Mundinger, F; Ostertag, C; Vogt, P | 1 |
| Borsa, J | 1 |
| Bloch, A | 1 |
| Westergaard, O | 1 |
| Coward, JE; Gentry, GA; Morse, PA | 1 |
| Zeuthen, E | 1 |
| Herbert, V; Kelly, A; Metz, J; Swett, VC; Waxman, S | 1 |
| Samuels, LL; Straw, JA | 1 |
| Loutit, JS; Musgrave, DR; Potter, AA | 1 |
| Andis, SL; Bewley, JR; Chen, VJ; Iversen, PW; Schultz, RM; Shih, C; Smith, PG; Tonkinson, JL | 1 |
| HUTCHISON, DJ; JOHNSON, AH | 1 |
| ALBRECHT, AM; HUTCHISON, DJ | 1 |
| SCHINKLER, R | 1 |
| GENTRY, GA; LAWSON, LA; RANDALL, CC | 1 |
| MORSE, PA; POTTER, VR | 1 |
| Croxford, R; Kim, YI; Lucock, M; Sohn, KJ; Yates, Z | 1 |
| Chang, XP; Cheng, DB; Cheng, YJ; He, F; Li, YM; Wu, Y; Zhuo, RX | 1 |
| Ai, Y; Chen, MM; Liu, D; Liu, F; Wang, J; Zhang, Z | 1 |
2 review(s) available for thymine and methotrexate
| Article | Year |
|---|---|
The fluoropyrimidines: biochemical mechanisms and design of clinical trials.
Topics: Antineoplastic Agents; Drug Therapy, Combination; Fluorouracil; Humans; Leucovorin; Metabolism; Methotrexate; Pyrimidines; Thymidine; Thymine | 1978 |
Chemotherapy and comparative biochemistry: G. H. A. Clowes memorial lecture.
Topics: Allopurinol; Animals; Antimetabolites; Azathioprine; Binding Sites; Drug Therapy; Enzyme Inhibitors; Enzyme Precursors; Folic Acid; Folic Acid Antagonists; Humans; Lactobacillus; Leukemia, Myeloid; Liver; Mercaptopurine; Methotrexate; Mice; Molecular Weight; Neoplasms; Nucleic Acids; Proteus; Purines; Research; Species Specificity; Thymine; Transferases; Uric Acid; Xanthine Oxidase | 1969 |
34 other study(ies) available for thymine and methotrexate
| Article | Year |
|---|---|
Accumulation of replicative DNA intermediates in Tetrahymena after excision-repairable damage to DNA.
Topics: Animals; Bromodeoxyuridine; Centrifugation, Density Gradient; DNA Repair; Methotrexate; Molecular Weight; Tetrahymena pyriformis; Thymine; Uridine | 1976 |
Sequential use of methotrexate, folinic acid, and cytosine arabinoside in the treatment of acute leukemia.
Topics: Adult; Bone Marrow; Bone Marrow Cells; Child; Cytarabine; Deoxyuridine; DNA; Drug Administration Schedule; Female; Humans; In Vitro Techniques; Leucovorin; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Mitosis; Thymidine; Thymine | 1976 |
Effects of methotrexate on intraperiplasmic and axenic growth of Bdellovibrio bacteriovorus.
Topics: Bacteria; Cell Division; Culture Media; Cytoplasm; DNA, Bacterial; Drug Antagonism; Escherichia coli; Methotrexate; Microscopy, Phase-Contrast; Mutation; Peptones; Saccharomyces; Tetrahydrofolates; Thymidine; Thymine; Thymine Nucleotides | 1975 |
Nutritional deficiencies in patients receiving cancer chemotherapy.
Topics: Antineoplastic Agents; Cachexia; Folic Acid Deficiency; Humans; Hypoproteinemia; Methotrexate; Neoplasms; Niacin; Nutrition Disorders; Nutritional Status; Pellagra; Riboflavin Deficiency; Thymine; Vitamin B Deficiency; Vitamin K Deficiency | 1990 |
Mechanism of thymineless death.
Topics: Acetylglucosamine; Cell Survival; Deoxyuracil Nucleotides; DNA Glycosylases; DNA Repair; Humans; Methotrexate; N-Glycosyl Hydrolases; Pyrophosphatases; Thymine; Uracil-DNA Glycosidase | 1986 |
[Effect of folic acid, methotrexate and thymine on antibody synthesis].
Topics: Animals; Antibody Formation; Antigen-Antibody Reactions; Erythrocytes; Folic Acid; Folic Acid Deficiency; gamma-Globulins; Hemolysin Proteins; Methotrexate; Mice; Rats; Thymine | 1970 |
Inhibition of plaque formation by myxoma and fibroma viruses with pyrimidine analogues.
Topics: Antiviral Agents; Benzimidazoles; Bromodeoxyuridine; Culture Techniques; Cytosine; DNA, Viral; Fibroma; Floxuridine; Fluorouracil; Idoxuridine; Mercaptopurine; Methotrexate; Myxoma virus; Nucleosides; Oncogenic Viruses; Thiosemicarbazones; Thymine | 1965 |
Effect of folinate on thymidine uptake by Pediococcus cerevisiae.
Topics: Aminopterin; Carbon Isotopes; Deoxyuridine; Floxuridine; Glucose; Hydrogen-Ion Concentration; Iodoacetates; Leucovorin; Methotrexate; Pediococcus; Temperature; Thymidine; Thymine; Tritium; Uracil | 1968 |
[Urinary elimination of beta aminoisobutyric acid in malignant hemopathies].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aminoisobutyric Acids; Asparagine; Child; Female; Hodgkin Disease; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Thymine; Vinblastine | 1971 |
Methylation of mammalian DNA: studies on Novikoff hepatoma cells in tissue culture.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Culture Techniques; Cytosine Nucleotides; DNA; Liver Neoplasms; Methionine; Methotrexate; Methylation; Neoplasms, Experimental; Purines; Pyrimidines; Rats; Thymine | 1969 |
Letter: On the source of "minor thymine" in DNA from a Novik off rat hepatoma cell line.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Chromatography, Paper; Cytosine; Deamination; Deoxycytidine; DNA; Liver; Liver Neoplasms; Methotrexate; Neoplasms, Experimental; Rats; Thymidine; Thymine; Tritium | 1973 |
Nucleic acid homology as a measure of genetic compatibility among streptococci and a strain of Diplococcus pneumoniae.
Topics: Carbon Isotopes; Culture Media; Cytosine; DNA, Bacterial; Drug Resistance, Microbial; Enterococcus faecalis; Erythromycin; Filtration; Guanine; Hot Temperature; Hybridization, Genetic; Methotrexate; Mutation; Nucleic Acid Denaturation; Serotyping; Streptococcus; Streptococcus pneumoniae; Thymine; Transformation, Genetic; Tritium | 1970 |
[Effect of thymine and adenine in nutrition on folic-acid deficient rats].
Topics: Adenine; Animals; Female; Folic Acid Deficiency; Male; Methotrexate; Rats; Thymine | 1974 |
Metabolic control of synthesis of the different forms of dihydrofolate reductase of the amethopterin-resistant Streptococcus faecium var. durans A k .
Topics: Chromatography, Gel; Drug Resistance, Microbial; Electrophoresis, Disc; Enzyme Activation; Enzyme Induction; Folic Acid; Folic Acid Antagonists; Hydrogen-Ion Concentration; Kinetics; Methotrexate; Potassium Chloride; Purines; Streptococcus; Tetrahydrofolate Dehydrogenase; Thymine | 1972 |
Thymidylate synthesis and aminopterin resistance in Bacillus subtilis.
Topics: Bacillus subtilis; Carbon Isotopes; Chromosome Mapping; Chromosomes; Drug Resistance, Microbial; In Vitro Techniques; Ligases; Methotrexate; Nucleotides; Thymine | 1966 |
Inhibition of methotrexate resistant mutant of Streptococcus faecalis by analogs of purine and pyrimidine.
Topics: Adenine; Adenine Nucleotides; Azaguanine; Drug Resistance, Microbial; Enterococcus faecalis; Guanine; Kinetics; Mercaptopurine; Methotrexate; Mutation; Nucleosides; Purines; Pyrimidines; Thioguanine; Thymine | 1970 |
[Clinical and experimental results of interstitial Brachy-Curie-therapy combined with radiation sensitizing agents in infiltrative growing brain neoplasms].
Topics: Animals; Brain Neoplasms; Bromodeoxyuridine; Carcinosarcoma; Cytidine; Fluorouracil; Guanosine; Iridium; Methotrexate; Neoplasms, Experimental; Radiation-Sensitizing Agents; Rats; Thymine | 1972 |
Cytotoxic mechanisms of folate antagonists.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Culture Media; Folic Acid Antagonists; HeLa Cells; L Cells; Leukemia, Experimental; Methotrexate; Thymine | 1971 |
Induction of the dihydrofolate reductase of Streptococcus faecium var. Durans by folic acid and by some of its derivatives.
Topics: Cell-Free System; Chemical Phenomena; Chemistry; Chloramphenicol; Culture Media; Dactinomycin; Enzyme Induction; Folic Acid; Leucovorin; Methotrexate; Purines; Streptococcus; Tetrahydrofolate Dehydrogenase; Thymine; Time Factors | 1970 |
Separation of two DNA polymerase fractions from Tetrahymena cells after excision-repairable damage to DNA.
Topics: Animals; Chromatography, Gel; DNA Nucleotidyltransferases; Electrons; Kinetics; Magnesium; Methotrexate; Nucleotides; Protein Biosynthesis; RNA; Sodium Chloride; Tetrahymena; Thymine; Tritium; Ultraviolet Rays | 1970 |
Effect of methotrexate on pyrimidine metabolism in regenerating rat liver.
Topics: Animals; Carbon Isotopes; DNA; Hepatectomy; Liver; Liver Regeneration; Male; Methotrexate; Nucleosides; Orotic Acid; Pyrimidines; Rats; Thymidine; Thymine | 1968 |
Thymine starvation by inhibition of uptake and synthesis of thymine-compounds in Tetrahymena.
Topics: Cell Division; DNA; Hot Temperature; Methotrexate; Nucleosides; Tetrahymena; Thymidine; Thymine; Tritium; Uracil; Uracil Nucleotides; Uridine | 1968 |
Deranged DNA synthesis by bone marrow from vitamin B-12-deficient humans.
Topics: Anemia, Macrocytic; Bone Marrow; Bone Marrow Cells; Deoxyuridine; DNA; Female; Folic Acid; Folic Acid Deficiency; Humans; In Vitro Techniques; Methionine; Methotrexate; Thymine; Tritium; Uridine; Vitamin B 12; Vitamin B 12 Deficiency | 1968 |
Improved therapeutic index with high-dose methotrexate: comparison of thymidine-purine rescue with citrovorum factor rescue in mice.
Topics: Animals; Brain Neoplasms; Deoxycytidine; DNA Replication; Dose-Response Relationship, Drug; Hypoxanthine; Hypoxanthines; Inosine; Leucovorin; Leukemia L1210; Methotrexate; Mice; Thymidine; Thymine | 1984 |
Thymine metabolism in Pseudomonas aeruginosa strain 1: the presence of a salvage pathway.
Topics: Culture Media; Methotrexate; Pseudomonas aeruginosa; Pyrimidines; Thymine; Trimethoprim | 1982 |
An assessment of the antithymine and antipurine characteristics of MTA (LY231514) in CCRF-CEM cells.
Topics: Cell Line; Folic Acid Antagonists; Glutamates; Guanine; Humans; Methotrexate; Pemetrexed; Purines; Tetrahydrofolates; Thymine | 2000 |
FOLIC ACID METABOLISM IN ANTIFOLIC-RESISTANT MUTANTS OF STREPTOCOCCUS FAECALIS.
Topics: Adenine; Drug Resistance, Microbial; Enterococcus faecalis; Folic Acid; Guanine; Metabolism; Methotrexate; Mutation; Purines; Research; Serine; Thymine; Xanthines | 1964 |
REPRESSION BY ADENINE OF THE FORMYLTETRAHYDROFOLATE SYNTHETASE IN AN ANTIFOLIC-RESISTANT MUTANT OF STREPTOCOCCUS FAECALIS.
Topics: Adenine; Bacteriological Techniques; Drug Resistance, Microbial; Enterococcus faecalis; Folic Acid; Formate-Tetrahydrofolate Ligase; Guanine; Ligases; Methotrexate; Mutation; Purines; Research; Tetrahydrofolate Dehydrogenase; Thymine | 1964 |
[INFLUENCING THE CELL DIVISION CYCLE IN CELL CULTURES BY VARIATION OF THE CULTURE MEDIUM].
Topics: Cell Division; Culture Media; DNA; Glycine; Leucine; Methotrexate; Purines; Thymidine; Thymine; Tissue Culture Techniques | 1964 |
REPLICATION OF A DEOXYRIBONUCLEIC ACID VIRUS IN THYMINE-DEFICIENT MAMMALIAN CELLS.
Topics: Animals; DNA; DNA Replication; DNA, Viral; Female; Floxuridine; Horses; Methotrexate; Nucleotides; Pharmacology; Pregnancy; Research; Thymidine; Thymine; Tissue Culture Techniques; Vertebrates; Virus Cultivation; Virus Replication; Viruses | 1964 |
PYRIMIDINE METABOLISM IN TISSUE CULTURE CELLS DERIVED FROM RAT HEPATOMAS. I. SUSPENSION CELL CULTURES DERIVED FROM THE NOVIKOFF HEPATOMA.
Topics: Animals; Carcinoma, Hepatocellular; Cell Culture Techniques; Floxuridine; Fluorouracil; Glycine; Liver Neoplasms; Liver Neoplasms, Experimental; Metabolism; Methotrexate; Mutation; Neoplasms; Neoplasms, Experimental; Nucleosides; Pharmacology; Pyrimidines; Rats; Research; Serine; Thymidine; Thymidine Kinase; Thymine; Tissue Culture Techniques; Toxicology; Uracil | 1965 |
Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate.
Topics: Alanine; Animals; Antimetabolites, Antineoplastic; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Cytosine; DNA Probes; Female; Fluorouracil; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genotype; Humans; Leucovorin; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Polymorphism, Genetic; Random Allocation; Thymidylate Synthase; Thymine; Transfection; Transplantation, Heterologous; Valine | 2004 |
Thymine-functionalized amphiphilic biodegradable copolymers for high-efficiency loading and controlled release of methotrexate.
Topics: Animals; Biocompatible Materials; Humans; Methotrexate; Polymers; Thymine | 2015 |
Lactobionic acid-modified thymine-chitosan nanoparticles as potential carriers for methotrexate delivery.
Topics: Antimetabolites, Antineoplastic; Cell Proliferation; Cell Survival; Chitosan; Disaccharides; Drug Carriers; Drug Delivery Systems; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; Methotrexate; Molecular Conformation; Nanoparticles; Thymine | 2021 |