thymine and levoleucovorin

thymine has been researched along with levoleucovorin in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's1 (7.69)18.2507
2000's3 (23.08)29.6817
2010's0 (0.00)24.3611
2020's3 (23.08)2.80

Authors

AuthorsStudies
Friedman, MA; Sadée, W1
Greenberg, ML; Waxman, S1
Grossowicz, N; Mandelbaum-Shavit, F1
Deibel, RH; Nowlan, SS1
Bloch, A1
Samuels, LL; Straw, JA1
Harwood, FG; Houghton, JA; Tillman, DM1
Croxford, R; Kim, YI; Lucock, M; Sohn, KJ; Yates, Z1
Chattopadhyay, S; Goldman, ID; Hanscom, M; Zhang, S; Zhao, R1
Cabezas-Herrera, J; Campo, LS; Navarro-Perán, E; Rodríguez-López, JN1
Carter, AM; Iveson, T; Mullamitha, S; Shiu, KK; Spooner, C; Stevens, D1
Antonuzzo, L; Castiglione, F; Di Costanzo, F; Lastraioli, E; Lavacchi, D; Messerini, L; Palmieri, VE1
Fukazawa, A; Hasegawa, S; Ishibashi, K; Ishida, H; Kamiyama, H; Koda, K; Kosugi, C; Kuramochi, H; Matsuda, A; Otsuka, T; Sakamoto, K; Sonoda, H; Yamada, T; Yamaguchi, S; Yoshida, H; Yoshida, Y; Yoshimatsu, K1

Reviews

1 review(s) available for thymine and levoleucovorin

ArticleYear
The fluoropyrimidines: biochemical mechanisms and design of clinical trials.
    Cancer chemotherapy and pharmacology, 1978, Volume: 1, Issue:2

    Topics: Antineoplastic Agents; Drug Therapy, Combination; Fluorouracil; Humans; Leucovorin; Metabolism; Methotrexate; Pyrimidines; Thymidine; Thymine

1978

Trials

1 trial(s) available for thymine and levoleucovorin

ArticleYear
Combination of TAS-102 and bevacizumab as third-line treatment for metastatic colorectal cancer: TAS-CC3 study.
    International journal of clinical oncology, 2021, Volume: 26, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Colorectal Neoplasms; Disease-Free Survival; Drug Combinations; Fluorouracil; Humans; Japan; Leucovorin; Pyrrolidines; Thymine; Trifluridine

2021

Other Studies

11 other study(ies) available for thymine and levoleucovorin

ArticleYear
Sequential use of methotrexate, folinic acid, and cytosine arabinoside in the treatment of acute leukemia.
    European journal of cancer, 1976, Volume: 12, Issue:8

    Topics: Adult; Bone Marrow; Bone Marrow Cells; Child; Cytarabine; Deoxyuridine; DNA; Drug Administration Schedule; Female; Humans; In Vitro Techniques; Leucovorin; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Mitosis; Thymidine; Thymine

1976
Effect of folinate on thymidine uptake by Pediococcus cerevisiae.
    Journal of bacteriology, 1968, Volume: 95, Issue:4

    Topics: Aminopterin; Carbon Isotopes; Deoxyuridine; Floxuridine; Glucose; Hydrogen-Ion Concentration; Iodoacetates; Leucovorin; Methotrexate; Pediococcus; Temperature; Thymidine; Thymine; Tritium; Uracil

1968
Group Q streptococci. II. Nutritional characteristics and growth relationship to thymine, folate, and folinate.
    Journal of bacteriology, 1967, Volume: 94, Issue:2

    Topics: Enterococcus faecalis; Folic Acid; Leucovorin; Streptococcus; Thymine

1967
Induction of the dihydrofolate reductase of Streptococcus faecium var. Durans by folic acid and by some of its derivatives.
    Biochimica et biophysica acta, 1970, Feb-24, Volume: 201, Issue:2

    Topics: Cell-Free System; Chemical Phenomena; Chemistry; Chloramphenicol; Culture Media; Dactinomycin; Enzyme Induction; Folic Acid; Leucovorin; Methotrexate; Purines; Streptococcus; Tetrahydrofolate Dehydrogenase; Thymine; Time Factors

1970
Improved therapeutic index with high-dose methotrexate: comparison of thymidine-purine rescue with citrovorum factor rescue in mice.
    Cancer research, 1984, Volume: 44, Issue:6

    Topics: Animals; Brain Neoplasms; Deoxycytidine; DNA Replication; Dose-Response Relationship, Drug; Hypoxanthine; Hypoxanthines; Inosine; Leucovorin; Leukemia L1210; Methotrexate; Mice; Thymidine; Thymine

1984
Ratio of 2'-deoxyadenosine-5'-triphosphate/thymidine-5'-triphosphate influences the commitment of human colon carcinoma cells to thymineless death.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:7

    Topics: Cell Death; Cell Survival; Clone Cells; Deoxyadenine Nucleotides; Deoxyadenosines; Fluorouracil; Humans; Kinetics; Leucovorin; Nucleosomes; Thymine; Thymine Nucleotides; Tumor Cells, Cultured; Tumor Stem Cell Assay

1995
Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate.
    Journal of the National Cancer Institute, 2004, Jan-21, Volume: 96, Issue:2

    Topics: Alanine; Animals; Antimetabolites, Antineoplastic; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Cytosine; DNA Probes; Female; Fluorouracil; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genotype; Humans; Leucovorin; Methotrexate; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred BALB C; Polymorphism, Genetic; Random Allocation; Thymidylate Synthase; Thymine; Transfection; Transplantation, Heterologous; Valine

2004
Loss of reduced folate carrier function and folate depletion result in enhanced pemetrexed inhibition of purine synthesis.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Feb-01, Volume: 11, Issue:3

    Topics: Animals; Blotting, Western; Cattle; Cell Division; Cell Line, Tumor; Culture Media; Dose-Response Relationship, Drug; Folic Acid; Folic Acid Antagonists; Glutamates; Guanine; HeLa Cells; Humans; Hypoxanthine; Leucovorin; Membrane Transport Proteins; Pemetrexed; Purines; Reduced Folate Carrier Protein; Serum; Thymidylate Synthase; Thymine

2005
Effects of folate cycle disruption by the green tea polyphenol epigallocatechin-3-gallate.
    The international journal of biochemistry & cell biology, 2007, Volume: 39, Issue:12

    Topics: Adenosine; Apoptosis; Caco-2 Cells; Camellia sinensis; Caspase 3; Catechin; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p16; DNA Methylation; DNA Replication; Fluorouracil; Folic Acid Antagonists; Gene Expression; Humans; Hypoxanthine; Leucovorin; Models, Biological; NF-kappa B; Protein Binding; Receptor, Adenosine A3; Tetrahydrofolate Dehydrogenase; Thymine; Transcription, Genetic

2007
Review of metastatic colorectal cancer treatment pathways and early clinical experience of trifluridine/tipiracil in the UK named patient programme.
    BMC cancer, 2020, Feb-03, Volume: 20, Issue:1

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Disease Progression; Drug Combinations; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Neoplasm Metastasis; Organoplatinum Compounds; Pyrrolidines; Thymine; Treatment Outcome; Trifluridine; United Kingdom; Uracil

2020
Evaluation of RAS mutational status through BEAMing assay to monitor disease progression of metastatic colorectal cancer: a case report.
    Anti-cancer drugs, 2020, Volume: 31, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Capecitabine; Cetuximab; Colorectal Neoplasms; Disease Progression; DNA Mutational Analysis; Drug Combinations; Fluorouracil; Humans; Leucovorin; Liquid Biopsy; Male; Middle Aged; Mutation; Phenylurea Compounds; Pyridines; Pyrrolidines; ras Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thymine; Trifluridine

2020