Compounds > thymine

thymine and dioxolane-thymine

thymine has been researched along with dioxolane-thymine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (80.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chu, CK; Liang, Y; Narayanasamy, J; Schinazi, RF1
Chu, CK; Liang, Y; Narayanasamy, J; Rapp, KL; Schinazi, RF1
Asif, G; Chu, CK; Delinsky, D; Hurwitz, SJ; McClure, HM; Narayanasamy, J; Obikhod, A; Schinazi, RF1
Chu, CK; Grier, JP; Liang, Y; Rapp, KL; Schinazi, RF; Sharon, A1
Bao, D; Furman, PA; Keilman, M; Niu, C; Otto, MJ; Rachakonda, S; Ross, BS; Sofia, MJ; Wang, P; Zennou, V1

Other Studies

5 other study(ies) available for thymine and dioxolane-thymine

ArticleYear
Phosphoramidate and phosphate prodrugs of (-)-beta-D-(2R,4R)-dioxolane-thymine: synthesis, anti-HIV activity and stability studies.
    Bioorganic & medicinal chemistry, 2006, Apr-01, Volume: 14, Issue:7

    Topics: Amides; Animals; Anti-HIV Agents; Cell Line, Tumor; Cell Proliferation; Chlorocebus aethiops; Dioxolanes; Drug Stability; HIV; Humans; Hydrolysis; Kinetics; Leukocytes, Mononuclear; Microbial Sensitivity Tests; Molecular Structure; Phosphates; Phosphoric Acids; Prodrugs; Stereoisomerism; Structure-Activity Relationship; Thymine; Vero Cells

2006
PAMAM dendrimers and branched polyethyleneglycol (nanoparticles) prodrugs of (-)-beta-D-(2R, 4R)-dioxolane-thymine (DOT) and their anti-HIV activity.
    Antiviral chemistry & chemotherapy, 2006, Volume: 17, Issue:6

    Topics: Animals; Anti-HIV Agents; Cell Survival; Dendrimers; Dioxolanes; Drug Carriers; HIV-1; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Nanoparticles; Polyamines; Polyethylene Glycols; Prodrugs; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thymine

2006
Pharmacokinetics of the anti-human immunodeficiency virus agent 1-(beta-D-dioxolane)thymine in rhesus monkeys.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7

    Topics: Administration, Oral; Animals; Antiviral Agents; Area Under Curve; Calibration; Chromatography, High Pressure Liquid; Dioxolanes; Female; Half-Life; HIV-1; Injections, Intravenous; Macaca mulatta; Mass Spectrometry; Metabolic Clearance Rate; Molecular Structure; Reference Standards; Reproducibility of Results; Thymine

2007
5'-O-Aliphatic and amino acid ester prodrugs of (-)-beta-D-(2R,4R)-dioxolane-thymine (DOT): synthesis, anti-HIV activity, cytotoxicity and stability studies.
    Bioorganic & medicinal chemistry, 2009, Feb-01, Volume: 17, Issue:3

    Topics: Animals; Anti-HIV Agents; Cell Line; Chlorocebus aethiops; Dioxolanes; Drug Stability; Half-Life; Humans; Leukocytes, Mononuclear; Prodrugs; Stereoisomerism; Thymine; Vero Cells

2009
Phosphoramidate prodrugs of (-)-β-D-(2R,4R)-dioxolane-thymine (DOT) as potent anti-HIV agents.
    Antiviral chemistry & chemotherapy, 2012, May-14, Volume: 22, Issue:5

    Topics: Amides; Anti-HIV Agents; Chromatography, High Pressure Liquid; Dioxolanes; Magnetic Resonance Spectroscopy; Mass Spectrometry; Phosphoric Acids; Prodrugs; Spectrophotometry, Ultraviolet; Thymine

2012