thymine and 8-hydroxyguanine

thymine has been researched along with 8-hydroxyguanine in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.13)18.7374
1990's4 (12.50)18.2507
2000's19 (59.38)29.6817
2010's7 (21.88)24.3611
2020's1 (3.13)2.80

Authors

AuthorsStudies
Alessio, H; Bergtold, DS; Cutler, RG; Simic, MG1
Ho, YS; Lin, JK; Lo, MJ; Wang, YJ1
Becker, D; Sevilla, M; Swarts, SG; Wheeler, KT1
Ohshima, H; Rubio, J; Yermilov, V; Yoshie, Y1
Dix, TA; Simandan, T; Sun, J1
Box, HC; Budzinski, EE; Dawidzik, JB; Ersing, N; Freund, HG; Iijima, H; Maccubbin, AE; Patrzyc, HB; Wallace, JC1
Allinson, SL; Brown, T; Fox, KR; Sahagun-Krause, H1
Okano, S; Yasui, A1
Johnson, RE; Prakash, L; Prakash, S; Washington, MT1
Bohr, VA; Dianov, GL; Nyaga, SG; Souza-Pinto, N; Stevnsner, T; Thybo, T1
Bohr, VA; Brosh, RM; Christiansen, M; Citterio, E; May, A; Muftuoglu, M; Nyaga, S; Selzer, RR; Tuo, J1
Back, JH; Chung, JH; Han, YS; Kim, KS; Park, YI1
Kathe, SD; Shen, GP; Wallace, SS1
Nakamura, N; Yonei, S; Yonekura, S; Zhang, QM1
Bhagwat, AS; Klapacz, J1
Back, JH; Chung, JH; Han, YS; Kim, DS; Park, JH1
O'Neill, P; Pearson, C; Shikazono, N; Thacker, J1
Haracska, L; Johnson, RE; Prakash, L; Prakash, S1
Charlet-Berguerand, N; Conaway, JW; Conaway, R; Egly, JM; Feuerhahn, S; Kong, SE; Ziserman, H1
Handa, H; Hayashida, M; Ikegami, T; Ito, S; Kuraoka, I; Kwei, JS; Nakabeppu, Y; Suzuki, K; Tanaka, K1
Bebenek, K; Blanco, L; Garcia-Diaz, M; Kunkel, TA; Povirk, LF; Zhou, RZ1
Hayter, S; Lamers, R; Matheson, CD1
Brosh, RM; Camerini-Otero, RD; Mason, AC; Sommers, JA; Suhasini, AN; Voloshin, ON; Wold, MS1
O'Neill, P; Shikazono, N1
Bohr, VA; Croteau, DL; Ghosh, AK; Janscak, P; Kulikowicz, T; Popuri, V; Ramamoorthy, M; Rossi, ML; Shevelev, I; Singh, DK1
Hashiguchi, K; Igarashi, K; Kato, S; Moriwaki, T; Yonekura, S; Zhang-Akiyama, QM1
Anusiewicz, I; Simons, J; Skurski, P; Świerszcz, I1
Foksinski, M; Gackowski, D; Olinski, R; Zarakowska, E1
Calkins, MJ; Dizdaroglu, M; Jaruga, P; Kirkali, G; Lloyd, RS; McCullough, AK; Owen, N; Vartanian, V1
Bose, A; Lee, CY; Lee, HT; Myong, S; Opresko, PL1
Boldinova, EO; Ignatov, A; Kulbachinskiy, A; Makarova, AV1
Kumar, N; Raja, S; Van Houten, B1

Reviews

5 review(s) available for thymine and 8-hydroxyguanine

ArticleYear
[Repair networks for base damage and single-strand breaks].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 2001, Volume: 46, Issue:8 Suppl

    Topics: Animals; DNA Damage; DNA Repair; DNA-Binding Proteins; DNA, Single-Stranded; Guanine; Humans; Poly(ADP-ribose) Polymerases; Thymine; X-ray Repair Cross Complementing Protein 1

2001
Base excision repair in nuclear and mitochondrial DNA.
    Progress in nucleic acid research and molecular biology, 2001, Volume: 68

    Topics: Adenine; Aging; Animals; Base Sequence; Cell Line; Cell Nucleus; Cell-Free System; DNA; DNA Damage; DNA Glycosylases; DNA Polymerase beta; DNA Repair; DNA-Formamidopyrimidine Glycosylase; DNA, Mitochondrial; Guanine; Hypoxanthine; Lymphocytes; Mammals; Mice; Mitochondria; Molecular Sequence Data; N-Glycosyl Hydrolases; Oxidants; Oxidation-Reduction; Oxidative Stress; Point Mutation; Proliferating Cell Nuclear Antigen; Rats; Thymine

2001
[Biological consequences and base excision repair mechanisms of oxidative base damage in DNA].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 2005, Volume: 50, Issue:4

    Topics: Animals; DNA; DNA Damage; DNA Glycosylases; DNA Repair; Guanine; Humans; Mutation; Oxidative Stress; Reactive Oxygen Species; Thymine

2005
Are 8-oxoguanine (8-oxoGua) and 5-hydroxymethyluracil (5-hmUra) oxidatively damaged DNA bases or transcription (epigenetic) marks?
    Mutation research. Genetic toxicology and environmental mutagenesis, 2014, Volume: 764-765

    Topics: Animals; Brain; Cell Nucleus; Chromatin; Cytidine Deaminase; DNA; DNA Damage; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression Regulation; Genetic Markers; Guanine; Liver; Mixed Function Oxygenases; Oxidation-Reduction; Pentoxyl; Proto-Oncogene Proteins; Swine; Thymine; Thymus Gland

2014
The involvement of nucleotide excision repair proteins in the removal of oxidative DNA damage.
    Nucleic acids research, 2020, 11-18, Volume: 48, Issue:20

    Topics: 5-Methylcytosine; DNA Damage; DNA Repair; DNA-Binding Proteins; Guanine; Humans; Oxidation-Reduction; Oxidative Stress; Thymine; Xeroderma Pigmentosum

2020

Other Studies

27 other study(ies) available for thymine and 8-hydroxyguanine

ArticleYear
Urine biomarkers for oxidative DNA damage.
    Basic life sciences, 1988, Volume: 49

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Biomarkers; Deoxyguanosine; DNA Damage; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Mice; Rats; Thymidine; Thymine

1988
Oxidative modification of DNA bases in rat liver and lung during chemical carcinogenesis and aging.
    Chemico-biological interactions, 1995, Volume: 94, Issue:2

    Topics: 2-Acetylaminofluorene; Adenine; Aging; Animals; Antineoplastic Agents; Disease Models, Animal; DNA Damage; DNA, Neoplasm; Gas Chromatography-Mass Spectrometry; Guanine; Hydrolysis; Liver; Liver Neoplasms, Experimental; Lung; Lung Neoplasms; Male; Methylamines; Nitrates; Oxidation-Reduction; Pyrimidines; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Thymine; Uracil

1995
Radiation-induced DNA damage as a function of hydration. II. Base damage from electron-loss centers.
    Radiation research, 1996, Volume: 145, Issue:3

    Topics: Adenine; Animals; Base Composition; Cytosine; DNA; DNA Damage; Electron Spin Resonance Spectroscopy; Electrons; Gas Chromatography-Mass Spectrometry; Guanine; Hydrolysis; Nucleic Acid Conformation; Pyrimidines; Salmon; Thymine

1996
Effects of carbon dioxide/bicarbonate on induction of DNA single-strand breaks and formation of 8-nitroguanine, 8-oxoguanine and base-propenal mediated by peroxynitrite.
    FEBS letters, 1996, Dec-09, Volume: 399, Issue:1-2

    Topics: Animals; Bicarbonates; Carbon Dioxide; Cattle; DNA Damage; DNA, Single-Stranded; Guanine; Nitrates; Thymine

1996
Oxidation of DNA bases, deoxyribonucleosides and homopolymers by peroxyl radicals.
    The Biochemical journal, 1998, Oct-15, Volume: 335 ( Pt 2)

    Topics: Adenine; Amidines; Base Pairing; Cytosine; Deoxyribonucleosides; DNA; Free Radicals; Guanine; Mass Spectrometry; Oxidation-Reduction; Purines; Pyrimidines; Reactive Oxygen Species; Thymine

1998
Double-base lesions are produced in DNA by free radicals.
    Archives of biochemistry and biophysics, 2000, Mar-01, Volume: 375, Issue:1

    Topics: Adenosine Triphosphate; Animals; Cattle; Chromatography, High Pressure Liquid; DNA; DNA Damage; Dose-Response Relationship, Radiation; Formamides; Free Radicals; Guanine; Pyrimidine Nucleosides; Single-Strand Specific DNA and RNA Endonucleases; Spectrometry, Mass, Fast Atom Bombardment; Thymine; Thymus Gland; X-Rays

2000
Recognition of GT mismatches by Vsr mismatch endonuclease.
    Nucleic acids research, 2000, 07-01, Volume: 28, Issue:13

    Topics: 2-Aminopurine; Base Pair Mismatch; Base Pairing; Base Sequence; Deoxyuridine; DNA; Endodeoxyribonucleases; Escherichia coli; Guanine; Kinetics; Purine Nucleosides; Ribonucleosides; Substrate Specificity; Thymine; Toluene

2000
Accuracy of lesion bypass by yeast and human DNA polymerase eta.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Jul-17, Volume: 98, Issue:15

    Topics: DNA Damage; DNA Replication; DNA-Directed DNA Polymerase; Guanine; Humans; Ligases; Saccharomyces cerevisiae; Thymine; Ubiquitin-Conjugating Enzymes; Ultraviolet Rays

2001
Differential requirement for the ATPase domain of the Cockayne syndrome group B gene in the processing of UV-induced DNA damage and 8-oxoguanine lesions in human cells.
    Nucleic acids research, 2002, Feb-01, Volume: 30, Issue:3

    Topics: Adenosine Triphosphatases; Amino Acid Motifs; Amino Acid Sequence; Apoptosis; Cell Extracts; Cell Line; Cell Survival; Cockayne Syndrome; Cytosine; DNA Damage; DNA Helicases; DNA Repair; DNA Repair Enzymes; Fibroblasts; Gene Expression Profiling; Genetic Complementation Test; Guanine; Humans; Hydrogen Peroxide; Mutation; Oligonucleotide Array Sequence Analysis; Poly-ADP-Ribose Binding Proteins; Protein Structure, Tertiary; Radiation Tolerance; RNA; Thymine; Ultraviolet Rays

2002
Endonuclease IV enhances base excision repair of endonuclease III from Methanobacterium thermoautotrophicum.
    DNA repair, 2003, May-13, Volume: 2, Issue:5

    Topics: Amino Acid Sequence; Deoxyribonuclease (Pyrimidine Dimer); Deoxyribonuclease IV (Phage T4-Induced); DNA; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Guanine; Methanobacterium; Molecular Sequence Data; Oligonucleotides; Oxygen; Protein Binding; Recombinant Proteins; Sequence Homology, Amino Acid; Sodium Chloride; Thymine

2003
Single-stranded breaks in DNA but not oxidative DNA base damages block transcriptional elongation by RNA polymerase II in HeLa cell nuclear extracts.
    The Journal of biological chemistry, 2004, Apr-30, Volume: 279, Issue:18

    Topics: Cell Extracts; Cell Nucleus; Cytosine; Deoxyribonucleosides; DNA Damage; DNA Repair; Guanine; HeLa Cells; Humans; Oxidation-Reduction; Pyrimidine Dimers; RNA Polymerase II; Templates, Genetic; Thymine; Transcription, Genetic

2004
Transcription promotes guanine to thymine mutations in the non-transcribed strand of an Escherichia coli gene.
    DNA repair, 2005, Jul-12, Volume: 4, Issue:7

    Topics: Codon, Nonsense; DNA Glycosylases; DNA Repair; DNA-Formamidopyrimidine Glycosylase; Escherichia coli; Escherichia coli Proteins; Genes, Bacterial; Guanine; Mutagenesis; Mutation; Thymine; Transcription, Genetic

2005
A distinct TthMutY bifunctional glycosylase that hydrolyzes not only adenine but also thymine opposite 8-oxoguanine in the hyperthermophilic bacterium, Thermus thermophilus.
    DNA repair, 2006, Aug-13, Volume: 5, Issue:8

    Topics: Adenine; Amino Acid Sequence; Base Pair Mismatch; Base Sequence; Binding Sites; DNA Glycosylases; DNA Primers; DNA Repair; Guanine; Molecular Sequence Data; Sequence Analysis, DNA; Sequence Homology; Thermus thermophilus; Thymine

2006
The roles of specific glycosylases in determining the mutagenic consequences of clustered DNA base damage.
    Nucleic acids research, 2006, Volume: 34, Issue:13

    Topics: Deoxyribonuclease (Pyrimidine Dimer); DNA Damage; DNA Glycosylases; DNA-Formamidopyrimidine Glycosylase; Escherichia coli; Escherichia coli Proteins; Guanine; Mutagenesis; Mutation; Thymine

2006
Role of hoogsteen edge hydrogen bonding at template purines in nucleotide incorporation by human DNA polymerase iota.
    Molecular and cellular biology, 2006, Volume: 26, Issue:17

    Topics: Base Pairing; Cytosine; DNA Damage; DNA Polymerase iota; DNA Primers; DNA-Directed DNA Polymerase; Guanine; Humans; Hydrogen Bonding; Kinetics; Purines; Templates, Genetic; Thymine

2006
RNA polymerase II bypass of oxidative DNA damage is regulated by transcription elongation factors.
    The EMBO journal, 2006, Nov-29, Volume: 25, Issue:23

    Topics: DNA Damage; DNA Helicases; DNA Repair; DNA Repair Enzymes; Elongin; Guanine; HeLa Cells; Humans; Oxidative Stress; Poly-ADP-Ribose Binding Proteins; RNA Polymerase II; Thymine; Transcription Factors; Transcription Factors, TFII; Transcription, Genetic; Transcriptional Elongation Factors; Uracil

2006
RNA polymerase II bypasses 8-oxoguanine in the presence of transcription elongation factor TFIIS.
    DNA repair, 2007, Jun-01, Volume: 6, Issue:6

    Topics: Adenine; Base Sequence; DNA Damage; DNA Repair; Guanine; HeLa Cells; Humans; Models, Chemical; Models, Genetic; Molecular Sequence Data; Oxygen; RNA Polymerase II; Thymine; Transcription, Genetic; Transcriptional Elongation Factors

2007
Tolerance for 8-oxoguanine but not thymine glycol in alignment-based gap filling of partially complementary double-strand break ends by DNA polymerase lambda in human nuclear extracts.
    Nucleic acids research, 2008, Volume: 36, Issue:9

    Topics: Base Pair Mismatch; Cell Extracts; Cell Nucleus; DNA Breaks, Double-Stranded; DNA Polymerase beta; DNA Repair; Guanine; HeLa Cells; Humans; Recombinant Fusion Proteins; Thymine

2008
Postmortem miscoding lesions in sequence analysis of human ancient mitochondrial DNA.
    Journal of molecular evolution, 2009, Volume: 68, Issue:1

    Topics: Adenine; Cytosine; DNA Damage; DNA, Mitochondrial; Guanine; Humans; Sequence Analysis; Thymine

2009
FANCJ helicase uniquely senses oxidative base damage in either strand of duplex DNA and is stimulated by replication protein A to unwind the damaged DNA substrate in a strand-specific manner.
    The Journal of biological chemistry, 2009, Jul-03, Volume: 284, Issue:27

    Topics: Basic-Leucine Zipper Transcription Factors; Breast Neoplasms; DNA; DNA Adducts; DNA Damage; DNA Helicases; Enzyme Activation; Fanconi Anemia; Fanconi Anemia Complementation Group Proteins; Female; Guanine; Humans; Oxidative Stress; Replication Protein A; Substrate Specificity; Thymine

2009
Biological consequences of potential repair intermediates of clustered base damage site in Escherichia coli.
    Mutation research, 2009, Oct-02, Volume: 669, Issue:1-2

    Topics: DNA Damage; DNA Repair; DNA-Formamidopyrimidine Glycosylase; DNA, Bacterial; DNA, Single-Stranded; Escherichia coli; Escherichia coli Proteins; Guanine; Mutation; Thymine

2009
The human RecQ helicases BLM and RECQL4 cooperate to preserve genome stability.
    Nucleic acids research, 2012, Volume: 40, Issue:14

    Topics: Cell Line; DNA; DNA Damage; Genomic Instability; Guanine; HeLa Cells; Humans; Protein Interaction Domains and Motifs; RecQ Helicases; S Phase; Sister Chromatid Exchange; Thymine

2012
Structural and functional properties of CiNTH, an endonuclease III homologue of the ascidian Ciona intestinalis: critical role of N-terminal region.
    Genes & genetic systems, 2012, Volume: 87, Issue:2

    Topics: Amino Acid Sequence; Animals; Ciona intestinalis; Deoxyribonuclease (Pyrimidine Dimer); DNA; DNA Damage; DNA Glycosylases; DNA Repair; Escherichia coli; Gene Expression Regulation; Guanine; Humans; Hydrogen Peroxide; Molecular Sequence Data; Reactive Oxygen Species; Sequence Alignment; Thymine; Uracil

2012
Mechanism for repair of thymine dimers by photoexcitation of proximal 8-oxo-7,8-dihydroguanine.
    The journal of physical chemistry. A, 2013, Feb-14, Volume: 117, Issue:6

    Topics: Dimerization; DNA; Guanine; Photochemical Processes; Quantum Theory; Thymine

2013
Enhanced sensitivity of Neil1
    DNA repair, 2016, Volume: 48

    Topics: Animals; Cytokines; DNA Damage; DNA Glycosylases; DNA Repair; Gene Expression Profiling; Gene Expression Regulation; Guanine; Inflammation; Mice; Mice, Knockout; Neutrophil Infiltration; Oxidative Stress; Pyrimidines; Reactive Oxygen Species; Skin; Thymine; Ultraviolet Rays; Uracil

2016
Molecular mechanisms by which oxidative DNA damage promotes telomerase activity.
    Nucleic acids research, 2017, Nov-16, Volume: 45, Issue:20

    Topics: Base Sequence; DNA; DNA Damage; DNA, Single-Stranded; G-Quadruplexes; Guanine; HEK293 Cells; Humans; Oxidative Stress; Protein Binding; Shelterin Complex; Telomerase; Telomere; Telomere Homeostasis; Telomere-Binding Proteins; Thymine

2017
The active site residues Gln55 and Arg73 play a key role in DNA damage bypass by S. cerevisiae Pol η.
    Scientific reports, 2018, 07-09, Volume: 8, Issue:1

    Topics: Arginine; Catalytic Domain; DNA Damage; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; Glycine; Guanine; Mutagenesis, Site-Directed; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thymine

2018