thymine and 5-methylcytosine

thymine has been researched along with 5-methylcytosine in 63 studies

Research

Studies (63)

TimeframeStudies, this research(%)All Research%
pre-19907 (11.11)18.7374
1990's13 (20.63)18.2507
2000's11 (17.46)29.6817
2010's27 (42.86)24.3611
2020's5 (7.94)2.80

Authors

AuthorsStudies
Ebright, RH; Ebright, YW; Gunasekera, A1
Bründl, K; Fritz, HJ; Hennecke, F; Kolmar, H1
Crain, PF1
Brown, TC; Jiricny, J1
Ehrlich, M; Gehrke, CW; Kuo, KC; Norris, KF; Wang, RY1
Harris, JS; Lu, LJ; Randerath, K; Tseng, WC1
Bird, AP1
Warren, RA1
Duker, NJ; Vairapandi, M1
Bhagwat, AS; Yebra, MJ1
Bandaru, B; Bhagwat, AS; Wyszynski, M1
Castro, GD; Castro, JA; Stamato, CJ1
Jaishree, TN; Wang, AH1
Cupples, CG; Létourneau, S; Ruiz, SM1
Brooks, PJ; Goldman, D; Marietta, C1
Bukowska, AM; Kuśmierek, JT1
Bhagwat, AS; Lutsenko, E2
Atwood, CV; Cupples, CG; Macintyre, G1
Holt, BJ; Holt, PG; Watt, PM; White, GP1
Iwai, S; O'Connor, TR; Pfeifer, GP; Yoon, JH1
AMOS, H; KORN, M1
DEYSSON, G; TRUHAUT, R1
Aoyama, T; Ishibe, T; Nagayama, S; Nakamura, T; Nakayama, T; Nishijo, K; Okamoto, T; Toguchida, J; Yasura, K1
Barone, S; Bennett, CF; Drygin, D1
Ariza, RR; Martínez-Macías, MI; Morales-Ruiz, T; Ortega-Galisteo, AP; Ponferrada-Marín, MI; Roldán-Arjona, T1
Fujimoto, K; Matsumura, T; Yoshimura, Y1
Hari, Y; Imanishi, T; Kodama, T; Mitsuoka, Y; Obika, S; Ohnishi, R1
Cannistraro, VJ; Taylor, JS1
Nomura, A; Okamoto, A; Tainaka, K1
Basu, AK; Brown, KL; Stone, MP1
Kumar, TS; Madsen, AS; Wengel, J1
Hanaoka, F; Iwai, S; Manabe, K; Masutani, C; Nishiguchi, K; Yamamoto, J1
Ariza, RR; Parrilla-Doblas, JT; Ponferrada-Marín, MI; Roldán-Arjona, T1
Babu, BR; Hrdlicka, PJ; Maity, J; Wengel, J; Østergaard, ME1
Nakamura, Y; Urata, H; Wada, S; Yamaguchi, E1
Hari, Y; Imanishi, T; Kodama, T; Obika, S1
Joseph, J; Schuster, GB1
Drohat, AC; MacKerell, AD; Maiti, A; Noon, MS; Pozharski, E1
Bhagwat, AS; Wijesinghe, P1
Couvé, S; Grin, I; Henriot, V; Ishchenko, AA; Moréra, S; Saparbaev, M; Vigouroux, A1
Bohn, MF; Brown, WL; Carpenter, MA; Harris, RS; Lackey, L; Land, AM; Law, EK; Leonard, B; Li, M; Rathore, A; Schiffer, CA; Shandilya, SM1
Jensen, TB; Jørgensen, AS; Madsen, AS; Wengel, J1
Brown, T; Fox, KR; Kimber, ST1
Brandmayr, C; Carell, T; Eisen, D; Hackner, B; Kashiwazaki, G; Kosmatchev, O; Kotljarova, O; Laube, SK; Leonhardt, H; Michalakis, S; Müller, M; Müller, U; Pfaffeneder, T; Raddaoui, N; Schär, P; Schiesser, S; Schuermann, D; Spada, F; Spruijt, CG; Steigenberger, B; Steinbacher, J; Truss, M; Vermeulen, M; Wagner, M1
Cadet, J; Madugundu, GS; Wagner, JR1
Hu, D; Jin, L; Min, S; Wang, L; Wang, W; Zhang, C1
Almo, SC; Fedorov, AA; Fedorov, EV; Hitchcock, DS; Raushel, FM1
Cheng, X; Hashimoto, H; Vertino, PM; Zhang, X1
Guengerich, FP1
Cheng, X; Corrêa, IR; Dai, N; Hashimoto, H; Pais, JE; Zhang, X; Zheng, Y1
Blumenthal, RM; Cheng, X; Hashimoto, H; Jin, P; Steves, AN; Wang, D; Zhang, X1
Foksinski, M; Gackowski, D; Gawronski, M; Modrzejewska, M; Olinski, R; Rzeszowska-Wolny, J; Skonieczna, M; Starczak, M; Zarakowska, E1
Blumenthal, RM; Cheng, X; Hong, S; Horton, JR; Speck, SH; Wang, D; Zhang, X1
Blumenthal, RM; Cheng, X; Horton, JR; Ren, R; Zhang, X1
Durec, M; Fiala, R; González-Jasso, E; González-Olvera, JC; Marek, R; Morales-García, MDRJ; Pless, RC1
Blumenthal, RM; Cheng, X; Horton, JR; Huang, Y; Li, J; Ren, R; Sun, D; Wang, D; Yang, J; Zhang, X1
Fujisaka, A; Hari, Y; Imanishi, T; Obika, S; Pang, J; Rahman, SMA; Takuma, H; Yoshikawa, H1
Nakatani, K; Yagi, Y; Yamada, T1
Lee, W; Matsika, S1
Gackowska, L; Gackowski, D; Labejszo, A1
Kumar, N; Raja, S; Van Houten, B1
Cao, W; Chang, C; Fang, GC; Li, J; Liang, C; Park, SH; Yang, Y1

Reviews

6 review(s) available for thymine and 5-methylcytosine

ArticleYear
Modified bases in bacteriophage DNAs.
    Annual review of microbiology, 1980, Volume: 34

    Topics: 2-Aminopurine; 5-Methylcytosine; Adenine; Bacteriophages; Base Composition; Chemical Phenomena; Chemistry; Chemistry, Physical; Cytosine; Deoxyribonucleases; DNA Replication; DNA, Viral; Nucleic Acid Conformation; Pentoxyl; Substrate Specificity; Templates, Genetic; Thymine; Transcription, Genetic; Uracil

1980
Principal causes of hot spots for cytosine to thymine mutations at sites of cytosine methylation in growing cells. A model, its experimental support and implications.
    Mutation research, 1999, Volume: 437, Issue:1

    Topics: 5-Methylcytosine; Cell Division; Cytosine; DNA Damage; DNA Methylation; DNA Repair; DNA, Bacterial; Escherichia coli; Humans; Models, Genetic; Point Mutation; Replicon; Thymine

1999
The Mechanisms of Generation, Recognition, and Erasure of DNA 5-Methylcytosine and Thymine Oxidations.
    The Journal of biological chemistry, 2015, Aug-21, Volume: 290, Issue:34

    Topics: 5-Methylcytosine; Dioxygenases; DNA Glycosylases; DNA Methylation; DNA Repair; Epigenesis, Genetic; Gene Expression; Humans; Iron; Ketoglutaric Acids; Methyltransferases; Models, Molecular; Oxidation-Reduction; Protein Processing, Post-Translational; Thymine; Transcription Factors

2015
Introduction: Metals in Biology: α-Ketoglutarate/Iron-Dependent Dioxygenases.
    The Journal of biological chemistry, 2015, Aug-21, Volume: 290, Issue:34

    Topics: 5-Methylcytosine; AlkB Homolog 4, Lysine Demethylase; Dioxygenases; DNA; DNA Damage; DNA Repair; Epigenesis, Genetic; Gene Expression; Humans; Iron; Isoenzymes; Ketoglutaric Acids; Multigene Family; Oxidation-Reduction; Protein Processing, Post-Translational; Thymine

2015
Detecting and interpreting DNA methylation marks.
    Current opinion in structural biology, 2018, Volume: 53

    Topics: 5-Methylcytosine; Animals; DNA; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Humans; Methyltransferases; Oxidation-Reduction; Thymine; Transcription Factors

2018
The involvement of nucleotide excision repair proteins in the removal of oxidative DNA damage.
    Nucleic acids research, 2020, 11-18, Volume: 48, Issue:20

    Topics: 5-Methylcytosine; DNA Damage; DNA Repair; DNA-Binding Proteins; Guanine; Humans; Oxidation-Reduction; Oxidative Stress; Thymine; Xeroderma Pigmentosum

2020

Other Studies

57 other study(ies) available for thymine and 5-methylcytosine

ArticleYear
DNA sequence determinants for binding of the Escherichia coli catabolite gene activator protein.
    The Journal of biological chemistry, 1992, Jul-25, Volume: 267, Issue:21

    Topics: 5-Methylcytosine; Base Sequence; Cyclic AMP Receptor Protein; Cytosine; DNA, Bacterial; Escherichia coli; Methylation; Molecular Sequence Data; Mutation; Substrate Specificity; Thermodynamics; Thymine; Uracil

1992
The vsr gene product of E. coli K-12 is a strand- and sequence-specific DNA mismatch endonuclease.
    Nature, 1991, Oct-24, Volume: 353, Issue:6346

    Topics: 5-Methylcytosine; Base Composition; Base Sequence; beta-Lactamases; Cytosine; DNA Repair; DNA, Bacterial; Endodeoxyribonucleases; Escherichia coli; Molecular Sequence Data; Recombinant Fusion Proteins; Thymine

1991
Analysis of 5-methylcytosine in DNA by isotope dilution gas chromatography-mass spectrometry.
    Methods in enzymology, 1990, Volume: 193

    Topics: 5-Methylcytosine; Cytosine; DNA; Gas Chromatography-Mass Spectrometry; Radioisotope Dilution Technique; Thymine

1990
A specific mismatch repair event protects mammalian cells from loss of 5-methylcytosine.
    Cell, 1987, Sep-11, Volume: 50, Issue:6

    Topics: 5-Methylcytosine; Animals; Base Composition; Base Sequence; Cell Line; Chlorocebus aethiops; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Repair; DNA, Recombinant; DNA, Viral; Guanine; Methylation; Simian virus 40; Thymine

1987
DNA cytosine methylation and heat-induced deamination.
    Bioscience reports, 1986, Volume: 6, Issue:4

    Topics: 5-Methylcytosine; Cytosine; Deamination; DNA, Bacterial; DNA, Single-Stranded; Escherichia coli; Hot Temperature; Humans; Kinetics; Methylation; Thymine; Uracil

1986
Specific effects of 5-fluoropyrimidines and 5-azapyrimidines on modification of the 5 position of pyrimidines, in particular the synthesis of 5-methyluracil and 5-methylcytosine in nucleic acids.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1983, Volume: 84

    Topics: 5-Methylcytosine; Animals; Azacitidine; Cytidine; Cytosine; DNA; Liver; Methylation; Mice; Pyrimidines; RNA, Transfer; Thymine

1983
DNA methylation and the frequency of CpG in animal DNA.
    Nucleic acids research, 1980, Apr-11, Volume: 8, Issue:7

    Topics: 5-Methylcytosine; Animals; Base Sequence; Cytosine; DNA; DNA Restriction Enzymes; Methylation; Mutation; Thymine

1980
Excision of ultraviolet-induced photoproducts of 5-methylcytosine from DNA.
    Mutation research, 1994, Volume: 315, Issue:2

    Topics: 5-Methylcytosine; Base Sequence; Cytosine; Deoxyribonuclease (Pyrimidine Dimer); Dinucleoside Phosphates; DNA; DNA Repair; Endodeoxyribonucleases; Humans; Methylation; Molecular Sequence Data; Polydeoxyribonucleotides; Thymine; Ultraviolet Rays

1994
A cytosine methyltransferase converts 5-methylcytosine in DNA to thymine.
    Biochemistry, 1995, Nov-14, Volume: 34, Issue:45

    Topics: 5-Methylcytosine; Cytosine; DNA; DNA-Cytosine Methylases; Escherichia coli; Humans; Methylation; Molecular Structure; Mutagenesis; Neoplasms; S-Adenosylhomocysteine; S-Adenosylmethionine; Thymine

1995
HpaII methyltransferase is mutagenic in Escherichia coli.
    Journal of bacteriology, 1995, Volume: 177, Issue:10

    Topics: 5-Methylcytosine; Base Sequence; Cytosine; DNA Repair; DNA-Cytosine Methylases; Escherichia coli; Haemophilus; Molecular Sequence Data; Mutagenesis; Thymine; Uracil

1995
5-methylcytosine attack by free radicals arising from bromotrichloromethane in a model system: structures of reaction products.
    Free radical biology & medicine, 1994, Volume: 17, Issue:5

    Topics: 5-Methylcytosine; Aerobiosis; Anaerobiosis; Bromotrichloromethane; Cytosine; DNA; Free Radicals; Gas Chromatography-Mass Spectrometry; Models, Chemical; Pentoxyl; Thymine

1994
Conformations of the alternating (C-T)n sequence under neutral and low pH.
    FEBS letters, 1994, Jan-10, Volume: 337, Issue:2

    Topics: 5-Methylcytosine; Base Composition; Base Sequence; Cytosine; DNA; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligoribonucleotides; Polydeoxyribonucleotides; Thymine

1994
Isolation and characterization of an Escherichia coli strain with a high frequency of C-to-T mutations at 5-methylcytosines.
    Journal of bacteriology, 1993, Volume: 175, Issue:16

    Topics: 5-Methylcytosine; Base Sequence; Chromosome Mapping; Cytosine; DNA Repair; Escherichia coli; Genes, Bacterial; Lac Operon; Molecular Sequence Data; Mutagenesis; Phenotype; Suppression, Genetic; Thymine

1993
DNA mismatch repair and DNA methylation in adult brain neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1996, Feb-01, Volume: 16, Issue:3

    Topics: 5-Methylcytosine; Animals; Base Composition; Base Sequence; Brain; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Damage; DNA Repair; Liver; Methylation; Molecular Sequence Data; Nerve Tissue Proteins; Neurons; Organ Specificity; Rats; Thymine; Thymus Gland; Uracil

1996
Miscoding properties of isoguanine (2-oxoadenine) studied in an AMV reverse transcriptase in vitro system.
    Acta biochimica Polonica, 1996, Volume: 43, Issue:1

    Topics: 5-Methylcytosine; Adenosine; Avian Myeloblastosis Virus; Base Composition; Cytosine; Deoxyribonucleotides; Guanosine; Kinetics; Polydeoxyribonucleotides; RNA-Directed DNA Polymerase; Substrate Specificity; Templates, Genetic; Thymine

1996
The role of the Escherichia coli mug protein in the removal of uracil and 3,N(4)-ethenocytosine from DNA.
    The Journal of biological chemistry, 1999, Oct-22, Volume: 274, Issue:43

    Topics: 5-Methylcytosine; Base Pair Mismatch; Cytosine; DNA Repair; DNA, Bacterial; Endodeoxyribonucleases; Escherichia coli; Humans; Mutagenesis; N-Glycosyl Hydrolases; Open Reading Frames; Point Mutation; Substrate Specificity; Thymine; Thymine DNA Glycosylase

1999
Lowering S-adenosylmethionine levels in Escherichia coli modulates C-to-T transition mutations.
    Journal of bacteriology, 2001, Volume: 183, Issue:3

    Topics: 5-Methylcytosine; Cytosine; DNA Glycosylases; DNA Methylation; DNA Repair; DNA-Cytosine Methylases; Escherichia coli; Hydrolases; Models, Genetic; Mutagenesis; N-Glycosyl Hydrolases; Point Mutation; S-Adenosylmethionine; Thymine; Uracil-DNA Glycosidase

2001
Differential patterns of methylation of the IFN-gamma promoter at CpG and non-CpG sites underlie differences in IFN-gamma gene expression between human neonatal and adult CD45RO- T cells.
    Journal of immunology (Baltimore, Md. : 1950), 2002, Mar-15, Volume: 168, Issue:6

    Topics: 5-Methylcytosine; Adenine; Adult; Calcium-Binding Proteins; CD3 Complex; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cloning, Molecular; CpG Islands; Cytosine; Dinucleotide Repeats; DNA Methylation; DNA Methyltransferase 3A; DNA-Binding Proteins; Fetal Blood; Gene Expression Regulation; Humans; Infant, Newborn; Interferon-gamma; Interleukin-4; Leukocyte Common Antigens; Microfilament Proteins; Promoter Regions, Genetic; Sequence Analysis, DNA; Sulfites; T-Lymphocyte Subsets; Thymine; Tumor Necrosis Factor-alpha

2002
Human thymine DNA glycosylase (TDG) and methyl-CpG-binding protein 4 (MBD4) excise thymine glycol (Tg) from a Tg:G mispair.
    Nucleic acids research, 2003, Sep-15, Volume: 31, Issue:18

    Topics: 5-Methylcytosine; Base Pair Mismatch; Deamination; DNA; DNA Damage; DNA Repair; Endodeoxyribonucleases; Guanine; Humans; Models, Genetic; Mutation; Oligonucleotides; Recombinant Proteins; Substrate Specificity; Thymine; Thymine DNA Glycosylase

2003
5-Methyl cytosine in the RNA of Escherichia coli.
    Biochimica et biophysica acta, 1958, Volume: 29, Issue:2

    Topics: 5-Methylcytosine; Escherichia coli; RNA; Thymine

1958
[Research on the antimitotic properties of antagonists of natural pyrimidine bases. II. 6-Azauracil, 6-azathymine, 2-thio-5-methylcytosine and 4-methyl-5-bis(beta-chloroethyl)-aminouracil].
    Bulletin de la Societe de chimie biologique, 1962, Volume: 44

    Topics: 5-Methylcytosine; Antimitotic Agents; Antineoplastic Agents; Pyrimidines; Thymine; Uracil

1962
Methylation in the core-promoter region of the chondromodulin-I gene determines the cell-specific expression by regulating the binding of transcriptional activator Sp3.
    The Journal of biological chemistry, 2004, Jul-02, Volume: 279, Issue:27

    Topics: 5-Methylcytosine; Azacitidine; Binding Sites; Blotting, Western; Bone and Bones; Cartilage; Cell Line, Tumor; Chondrocytes; Chromatin; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA-Binding Proteins; Genes, Reporter; Humans; Intercellular Signaling Peptides and Proteins; Luciferases; Membrane Proteins; Precipitin Tests; Promoter Regions, Genetic; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering; Sp1 Transcription Factor; Sp3 Transcription Factor; Sulfites; Thymine; Transcription Factors; Transcription, Genetic

2004
Sequence-dependent cytotoxicity of second-generation oligonucleotides.
    Nucleic acids research, 2004, Volume: 32, Issue:22

    Topics: 5-Methylcytosine; Base Pairing; Base Sequence; Caspase 3; Caspases; Cell Line; Cell Proliferation; Humans; Kinetics; Lysosomes; Necrosis; Oligonucleotides, Antisense; Peptide Hydrolases; Thymine

2004
DEMETER and REPRESSOR OF SILENCING 1 encode 5-methylcytosine DNA glycosylases.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, May-02, Volume: 103, Issue:18

    Topics: 5-Methylcytosine; Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Cytosine; DNA Glycosylases; DNA Methylation; DNA Repair; Epigenesis, Genetic; Gene Silencing; Humans; Molecular Sequence Data; N-Glycosyl Hydrolases; Nuclear Proteins; Sequence Alignment; Thymine; Trans-Activators

2006
Photochemical transition of 5-methylcytosine to thymine by DNA photoligation.
    Nucleic acids symposium series (2004), 2007, Issue:51

    Topics: 5-Methylcytosine; Chromatography, High Pressure Liquid; DNA; Oligodeoxyribonucleotides; Photochemistry; Thymine

2007
A bridged nucleic acid, 2',4'-BNA COC: synthesis of fully modified oligonucleotides bearing thymine, 5-methylcytosine, adenine and guanine 2',4'-BNA COC monomers and RNA-selective nucleic-acid recognition.
    Nucleic acids research, 2009, Volume: 37, Issue:4

    Topics: 5-Methylcytosine; Adenine; Base Pair Mismatch; Bridged-Ring Compounds; Circular Dichroism; DNA; Guanine; Nucleic Acid Conformation; Nucleic Acid Denaturation; Nucleic Acids; Oligonucleotides; RNA; Thymine

2009
Acceleration of 5-methylcytosine deamination in cyclobutane dimers by G and its implications for UV-induced C-to-T mutation hotspots.
    Journal of molecular biology, 2009, Oct-09, Volume: 392, Issue:5

    Topics: 5-Methylcytosine; Animals; Deamination; DNA; Guanine; Models, Biological; Models, Molecular; Point Mutation; Pyrimidine Dimers; Salmon; Thymine; Ultraviolet Rays

2009
Osmium complex binding to mismatched methylcytosine: effect of adjacent bases.
    Nucleic acids symposium series (2004), 2009, Issue:53

    Topics: 5-Methylcytosine; Base Pair Mismatch; Osmium; Oxidation-Reduction; Thymine

2009
The cis-(5R,6S)-thymine glycol lesion occupies the wobble position when mismatched with deoxyguanosine in DNA.
    Biochemistry, 2009, Oct-20, Volume: 48, Issue:41

    Topics: 5-Methylcytosine; Base Pairing; Chromatography, High Pressure Liquid; Deoxyguanosine; DNA; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Oligodeoxyribonucleotides; Protons; Thymine

2009
LNA 5'-phosphoramidites for 5'→3'-oligonucleotide synthesis.
    Organic & biomolecular chemistry, 2010, Nov-07, Volume: 8, Issue:21

    Topics: 5-Methylcytosine; Candida; Fungal Proteins; Lipase; Molecular Structure; Oligonucleotides; Organophosphorus Compounds; Stereoisomerism; Thymine

2010
Photosensitized [2 + 2] cycloaddition of N-acetylated cytosine affords stereoselective formation of cyclobutane pyrimidine dimer.
    Nucleic acids research, 2011, Volume: 39, Issue:3

    Topics: 5-Methylcytosine; DNA-Directed DNA Polymerase; Humans; Hydrogen-Ion Concentration; Hydrolysis; Oligonucleotides; Organophosphorus Compounds; Photochemical Processes; Pyrimidine Dimers; Stereoisomerism; Temperature; Thymine; Ultraviolet Rays

2011
A discontinuous DNA glycosylase domain in a family of enzymes that excise 5-methylcytosine.
    Nucleic acids research, 2011, Volume: 39, Issue:4

    Topics: 5-Methylcytosine; Amino Acid Sequence; Arabidopsis Proteins; Base Sequence; DNA; DNA Glycosylases; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nuclear Proteins; Protein Structure, Tertiary; Sequence Alignment; Structural Homology, Protein; Substrate Specificity; Thymine

2011
Novel insights into the use of Glowing LNA as nucleic acid detection probes--influence of labeling density and nucleobases.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: 5-Methylcytosine; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Nucleic Acid Probes; Oligonucleotides; Pyrenes; Quantum Theory; Spectrometry, Fluorescence; Thymine; Transition Temperature

2010
Pyrimidine-pyrimidine base pairs stabilized by silver(I) ions.
    Chemical communications (Cambridge, England), 2011, Jan-21, Volume: 47, Issue:3

    Topics: 5-Methylcytosine; Base Pair Mismatch; Base Pairing; Cytosine; Hydrogen Bonding; Ions; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Pyrimidines; Silver; Thymine

2011
2'-O,4'-C-methyleneoxymethylene bridged nucleic acids (2',4'-BNA(COC)).
    Methods in molecular biology (Clifton, N.J.), 2011, Volume: 764

    Topics: 5-Methylcytosine; Adenine; Biological Products; Bridged-Ring Compounds; Chemistry, Pharmaceutical; Cytosine; DNA; Guanine; Nucleosides; Oligonucleotides; Oligonucleotides, Antisense; Organophosphorus Compounds; RNA; Thymine

2011
Oxidatively generated damage to DNA at 5-methylcytosine mispairs.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2012, Volume: 11, Issue:6

    Topics: 5-Methylcytosine; Adenine; Base Pair Mismatch; DNA; DNA Damage; Oxidation-Reduction; Thymine; Ultraviolet Rays

2012
Lesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNA.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, May-22, Volume: 109, Issue:21

    Topics: 5-Methylcytosine; Catalytic Domain; CpG Islands; Crystallography; DNA Repair; Enzyme Activation; Escherichia coli; Escherichia coli Proteins; Humans; Mutagenesis; N-Glycosyl Hydrolases; Protein Structure, Tertiary; Substrate Specificity; Thymine; Thymine DNA Glycosylase; Uracil; Uracil-DNA Glycosidase; Water

2012
Efficient deamination of 5-methylcytosines in DNA by human APOBEC3A, but not by AID or APOBEC3G.
    Nucleic acids research, 2012, Volume: 40, Issue:18

    Topics: 5-Methylcytosine; APOBEC-3G Deaminase; Cytidine Deaminase; Deamination; Escherichia coli; Humans; Protein Structure, Tertiary; Proteins; Thymine

2012
Biochemical and structural characterization of the glycosylase domain of MBD4 bound to thymine and 5-hydroxymethyuracil-containing DNA.
    Nucleic acids research, 2012, Volume: 40, Issue:19

    Topics: 5-Methylcytosine; Bacteria; Catalytic Domain; Cytosine; DNA; Endodeoxyribonucleases; Humans; Models, Molecular; Pentoxyl; Protein Structure, Tertiary; Substrate Specificity; Thymine; Thymine DNA Glycosylase

2012
Methylcytosine and normal cytosine deamination by the foreign DNA restriction enzyme APOBEC3A.
    The Journal of biological chemistry, 2012, Oct-05, Volume: 287, Issue:41

    Topics: 5-Methylcytosine; Cytidine Deaminase; Deamination; DNA; Enzyme Induction; HEK293 Cells; Humans; Immunity, Innate; Interferons; Plasmids; Proteins; Thymine; Uracil

2012
Large scale synthesis of 2'-amino-LNA thymine and 5-methylcytosine nucleosides.
    The Journal of organic chemistry, 2012, Dec-07, Volume: 77, Issue:23

    Topics: 5-Methylcytosine; Molecular Structure; Nucleosides; Organophosphorus Compounds; Thymidine Monophosphate; Thymine

2012
A mutant of uracil DNA glycosylase that distinguishes between cytosine and 5-methylcytosine.
    PloS one, 2014, Volume: 9, Issue:4

    Topics: 5-Methylcytosine; Bacterial Proteins; Base Sequence; Cytosine; DNA; Escherichia coli; Gene Expression; Molecular Sequence Data; Mutation; Oligonucleotides; Recombinant Proteins; Substrate Specificity; Thymine; Uracil; Uracil-DNA Glycosidase

2014
Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA.
    Nature chemical biology, 2014, Volume: 10, Issue:7

    Topics: 5-Methylcytosine; Animals; Base Sequence; Carbon Isotopes; Chromatin Assembly and Disassembly; Chromatography, Liquid; Cytosine; Dioxygenases; DNA; DNA-Binding Proteins; Embryonic Stem Cells; Gene Expression; Mice; Molecular Sequence Data; Oxidation-Reduction; Pentoxyl; Protein Binding; Proto-Oncogene Proteins; Spectrometry, Mass, Electrospray Ionization; Thymine; Transcription Factors

2014
Hydroxyl-radical-induced oxidation of 5-methylcytosine in isolated and cellular DNA.
    Nucleic acids research, 2014, Volume: 42, Issue:11

    Topics: 5-Methylcytosine; Cytosine; DNA; DNA Damage; DNA Methylation; Hydroxyl Radical; Oxidation-Reduction; Thymine

2014
Is the contribution of cis and trans protonated 5-methylcytosine-SO3(-) isomers equal in the conversion to thymine-SO3(-) under bisulfite conditions? A theoretical perspective.
    Physical chemistry chemical physics : PCCP, 2014, Aug-14, Volume: 16, Issue:30

    Topics: 5-Methylcytosine; Isomerism; Models, Molecular; Protons; Sulfates; Sulfites; Thymine

2014
Discovery of a bacterial 5-methylcytosine deaminase.
    Biochemistry, 2014, Dec-02, Volume: 53, Issue:47

    Topics: 5-Methylcytosine; Amino Acid Sequence; Bacteria; Biocatalysis; Catalytic Domain; Cell Line; Cytosine Deaminase; Flucytosine; Models, Molecular; Molecular Sequence Data; Phylogeny; Thymine

2014
Structure of Naegleria Tet-like dioxygenase (NgTet1) in complexes with a reaction intermediate 5-hydroxymethylcytosine DNA.
    Nucleic acids research, 2015, Dec-15, Volume: 43, Issue:22

    Topics: 5-Methylcytosine; Amino Acid Substitution; Catalytic Domain; Cytosine; Dioxygenases; DNA; Models, Molecular; Naegleria; Thymine

2015
Distinctive Klf4 mutants determine preference for DNA methylation status.
    Nucleic acids research, 2016, 12-01, Volume: 44, Issue:21

    Topics: 5-Methylcytosine; Animals; CpG Islands; Crystallography, X-Ray; DNA; DNA Methylation; Fluorescence Polarization; HEK293 Cells; Humans; Hydrogen Bonding; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Mice; Mutation; Proline; Protein Conformation; Thymine

2016
Vitamin C enhances substantially formation of 5-hydroxymethyluracil in cellular DNA.
    Free radical biology & medicine, 2016, Volume: 101

    Topics: 5-Methylcytosine; Ascorbic Acid; Cytosine; DNA; DNA Methylation; HCT116 Cells; Humans; Mixed Function Oxygenases; Oxidation-Reduction; Pentoxyl; Proto-Oncogene Proteins; Spectrometry, Mass, Electrospray Ionization; Thymine

2016
Methyl-dependent and spatial-specific DNA recognition by the orthologous transcription factors human AP-1 and Epstein-Barr virus Zta.
    Nucleic acids research, 2017, 03-17, Volume: 45, Issue:5

    Topics: 5-Methylcytosine; Base Pairing; Binding Sites; DNA; DNA Methylation; Humans; Protein Binding; Protein Multimerization; Proto-Oncogene Proteins c-jun; Response Elements; Thymine; Trans-Activators; Transcription Factor AP-1

2017
Protonation of Nucleobases in Single- and Double-Stranded DNA.
    Chembiochem : a European journal of chemical biology, 2018, 10-04, Volume: 19, Issue:19

    Topics: 5-Methylcytosine; Adenine; Base Sequence; DNA, Single-Stranded; Guanine; Hydrogen-Ion Concentration; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Osmolar Concentration; Protons; Thymine

2018
Structural basis for effects of CpA modifications on C/EBPβ binding of DNA.
    Nucleic acids research, 2019, 02-28, Volume: 47, Issue:4

    Topics: 5-Methylcytosine; CCAAT-Enhancer-Binding Protein-beta; Conserved Sequence; CpG Islands; Crystallography, X-Ray; Cytosine; DNA; DNA Methylation; DNA-Binding Proteins; E-Box Elements; Gene Expression Regulation; Promoter Regions, Genetic; Protein Conformation; Thymine; Transcription Factor AP-1

2019
Effective syntheses of 2',4'-BNA
    Bioorganic & medicinal chemistry, 2019, 04-15, Volume: 27, Issue:8

    Topics: 5-Methylcytosine; Adenine; Bridged-Ring Compounds; Glycosylation; Guanine; Nucleotides; Oligonucleotides; Thymine; Transition Temperature; Ultraviolet Rays

2019
Chemical Probing of Thymine in the TGG/CGG Triad to Explore the Deamination of 5-Methylcytosine in the CGG Repeat.
    Biochemistry, 2020, 07-28, Volume: 59, Issue:29

    Topics: 2,2'-Dipyridyl; 5-Methylcytosine; Deamination; Methylation; Naphthyridines; Thymine; Trinucleotide Repeat Expansion; Trinucleotide Repeats

2020
Stabilization of the Triplet Biradical Intermediate of 5-Methylcytosine Enhances Cyclobutane Pyrimidine Dimer (CPD) Formation in DNA.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2020, Nov-06, Volume: 26, Issue:62

    Topics: 5-Methylcytosine; DNA; Pyrimidine Dimers; Thymine

2020
Analysis of 5-Hydroxymethyluracil Levels Using Flow Cytometry.
    Methods in molecular biology (Clifton, N.J.), 2021, Volume: 2198

    Topics: 5-Methylcytosine; Chromatography, Liquid; Cytosine; DNA; DNA Methylation; Epigenesis, Genetic; Flow Cytometry; Humans; Oxidation-Reduction; Pentoxyl; Single-Cell Analysis; Tandem Mass Spectrometry; Thymine

2021
Screening of glycosylase activity on oxidative derivatives of methylcytosine: Pedobacter heparinus SMUG2 as a formylcytosine- and carboxylcytosine-DNA glycosylase.
    DNA repair, 2022, Volume: 119

    Topics: 5-Methylcytosine; Cytosine; DNA; DNA Repair; Humans; Oxidative Stress; Pedobacter; Thymine; Thymine DNA Glycosylase; Uracil; Uracil-DNA Glycosidase

2022