thymidine has been researched along with tyrosine in 153 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 46 (30.07) | 18.7374 |
| 1990's | 72 (47.06) | 18.2507 |
| 2000's | 30 (19.61) | 29.6817 |
| 2010's | 5 (3.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cohn, ZA; Hubbard, AL | 1 |
| Kurtz, MJ; Makarski, JS; Niles, RM; Rutenburg, AM | 1 |
| Warshawsky, H | 1 |
| Halpern, A; Stöcklin, G | 1 |
| Degrand, F; Dormont, J; Galanaud, P; Raynaud, M; Sobel, A; Wallon, C | 1 |
| Degrand, F; Dormont, J; Galanaud, P; Raynaud, M | 1 |
| Backer, JM; Haring, E; Kahn, CR; Siddle, K; White, MF; Wilden, PA | 1 |
| Blume-Jensen, P; Claesson-Welsh, L; Landgren, E; Wennström, S | 1 |
| Roth, RA; Zhang, B | 1 |
| Harwerth, IM; Hynes, NE; Marte, BM; Wels, W | 1 |
| Davis, RJ; Latour, DA; Raden, DL; Stanley, K; Theroux, SJ | 1 |
| Bradshaw, RA; Raffioni, S | 1 |
| Akanuma, Y; Chatani, Y; Izumi, T; Kadowaki, T; Kasuga, M; Kohno, M; Tamemoto, H; Tobe, K; Ueki, K; Yazaki, Y | 1 |
| Falick, AM; Shaw, AA; Shetlar, MD | 1 |
| Abraham, SM; Baylink, DJ; Finkelman, RD; Lau, KH | 1 |
| Davidai, G; Hazum, E; Lee, A; Schvartz, I | 1 |
| Asao, H; Beckers, T; Engels, JW; Kumaki, S; Kurahayashi, Y; Nakamura, M; Sugamura, K; Takeshita, T | 1 |
| Olefsky, JM; Takata, Y; Webster, NJ | 1 |
| Akanuma, Y; Ando, A; Kaburagi, Y; Koshio, O; Momomura, K; Sakura, H; Tamori, Y; Tobe, K; Yamamoto-Honda, R; Yazaki, Y | 1 |
| Backer, JM; Myers, MG; Siddle, K; White, MF | 1 |
| Felder, S; Millauer, B; Schlessinger, J; Seedorf, K; Ullrich, A | 1 |
| Brunetti, A; Goldfine, ID; Han, XL; Maddux, B; Sung, CK; Yamamoto-Honda, R | 1 |
| Cannistra, SA; DiCarlo, J; Druker, B; Griffin, JD; Kanakura, Y | 1 |
| Brunetti, A; Goldfine, ID; Hawley, DM; Maddux, BA; Patel, R; Rafaeloff, R; Sbraccia, P; Sung, CK | 1 |
| Holecek, M; Palicka, V; Simek, J; Zadák, Z | 1 |
| Hidaka, Y; Ishida, F; Kamei, T; Nagata, Y | 1 |
| Gorray, KC; Maimon, J; Schneider, BS | 1 |
| Baker, M; Fung, M; Greene, WC; May, C; McGill, M; Mills, GB; Sutherland, R | 1 |
| Basch, PF | 1 |
| Dizdaroglu, M; Simic, MG | 1 |
| Thomson, LA; Vaughn, JC | 1 |
| Ord, MG; Stocken, LA | 1 |
| Calegari, L; Canepari, P; Fontana, R; Satta, G | 1 |
| Melcher, U; Uhr, JW | 1 |
| Akiba, H; Kato, T; Nakano, H; Seiji, M | 1 |
| Amkraut, AA; Mackler, BF; Malley, A | 1 |
| Jungkind, DL; Wood, RC | 1 |
| Alkan, SS; Goodman, JW; Nitecki, DE | 1 |
| Erbstoeszer, JW; Siddhikol, C; Weisblum, B | 1 |
| Laufs, R; Walker, W | 1 |
| Bluestein, HG | 1 |
| Gubenko, IS | 1 |
| Abell, CW; Hodgins, DS; Stith, WJ | 1 |
| Green, I; Paul, WE; Shevach, EM | 1 |
| Nadakavukaren, MJ; Nollen, PM | 1 |
| Weintraub, H | 1 |
| Medić, M; Novak, D; Salaj-Smic, E; Wrischer, M; Zgaga, V | 1 |
| Altman, S; Schaefer, KP; Söll, D | 1 |
| Smilowitz, H | 1 |
| Bajt, JE; Nollen, PM; Pyne, JL | 1 |
| Nauciel, C | 1 |
| Alberico, RA; Nollen, PM; Restaino, AL | 1 |
| Moseley, C; Nollen, PM | 1 |
| Anfinsen, CB; Eastlake, A; Furie, B; Schechter, AN | 1 |
| Moran, D | 1 |
| Hu, F; Kitano, Y | 2 |
| Benacerraf, B; Bluestein, HG; Green, I; Maurer, PH | 1 |
| Nauciel, C; Raynaud, M | 1 |
| Dimicoli, JL; Hélène, C; Montenay-Garestier, T | 1 |
| Bultmann, H; Clever, U | 1 |
| Fischer, RD; Schachtschabel, D; Zilliken, F | 1 |
| Nollen, PM | 1 |
| Evans, EA | 1 |
| Fox, BW; Fox, M | 1 |
| Dizdaroglu, M | 1 |
| Hoppe, J; Hoppe, V; Karenberg, TA; Simm, A | 1 |
| Molloy, CJ; Taylor, DS; Weber, H | 1 |
| Domin, J; Higgins, T; Rozengurt, E | 1 |
| Gause, KC; LeRoy, EC; Lubinus, M; Meier, KE; Smith, EA; Trojanowska, M | 1 |
| Diamantstein, T; Dorsch, M; Hock, H | 1 |
| Kato, H; LeRoith, D; Mastick, CC; Roberts, CT; Saltiel, AR | 1 |
| Boswell, HS; Burgess, GS; Collart, FR; Gharehbaghi, K; Huberman, E; Jayaram, HN; Litz-Jackson, S | 1 |
| Cantley, LC; Carraway, KL; Diamonti, AJ; Soltoff, SP | 1 |
| Carpenter, G; Claesson-Welsh, L; Engström, U; Eriksson, A; Heldin, CH; Hellman, U; Nånberg, E; Rönnstrand, L; Rupp, E | 1 |
| Bittorf, T; Busfield, SJ; Callus, B; Cull, VS; Klinken, SP; Tilbrook, PA | 1 |
| Chen, JK; Cheng, HP; Hung, LM; Tsai, CH | 1 |
| Tsai, PS; Weiner, RI; Werner, S | 1 |
| Chang, JH; Niemann, H; Parsons, SJ; Smola, U; Tamura, T; Trouliaris, S | 1 |
| Buchholz, MJ; Kim, YH; Nordin, AA | 1 |
| Aaronson, SA; Gutkind, JS; Keegan, AD; Li, W; Lienhard, GE; Myers, MG; Pacini, S; Sun, XJ; Wang, LM; White, MF | 1 |
| Rozengurt, E; Seckl, M | 1 |
| Amaral, MC; Kumar, G; Miles, S; Nel, AE | 1 |
| Clunn, G; Hughes, AD; Patel, M; Schachter, M; Wijetunge, S | 1 |
| Blakesley, VA; Kato, H; LeRoith, D; Roberts, CT | 1 |
| Chio, CL; Huff, RM; Lajiness, ME | 1 |
| Hajjar, JJ; Oliver, BL; Sha'afi, RI | 1 |
| Emerling, D; Hashimoto, Y; Horie, Y; Kinoshita, M; Kurokawa, K; Nakao, A; Tsukamoto, K; Watanabe, T | 1 |
| Blakesley, VA; Faria, TN; Kato, H; LeRoith, D; Roberts, CT; Stannard, B | 1 |
| Claesson-Welsh, L; Heldin, CH; Mori, S | 1 |
| Decker, SJ | 1 |
| Katamine, S; Kohno, T; Miyamoto, T; Miyazaki, Y; Moriuchi, R; Tomonaga, M | 1 |
| Inagami, T; Inui, H; Kondo, T; Konishi, F | 1 |
| Brogi, E; Couffinhal, T; Isner, JM; Kearney, M; Kim, EA; Namiki, A; Varticovski, L; Wu, T | 1 |
| Blakesley, VA; Faria, TN; Helman, LJ; Kalebic, T; LeRoith, D; Roberts, CT; Stannard, B | 1 |
| Boylan, JM; Gruppuso, PA; Lipeski, LE | 1 |
| Chevalier, B; Duclos, MJ; Goddard, C; Remignon, H; Ricard, FH; Simon, J | 1 |
| Hamaguchi, M; Hayakawa, T; Iwata, H; Koike, T; Noguchi, T; Shinagawa, A; Suzuki, M; Yamashita, K | 1 |
| Freissmuth, M; Gloria-Maercker, E; Höller, C; Mancusi, G; Schütz, W; Sexl, V | 1 |
| Baylink, DJ; Graves, LM; Lau, KH; Wu, LW; Yoon, HK | 1 |
| Awazu, M | 1 |
| Hwang, C; Lee, J; Lee, M; Slavkin, H; Warburton, D | 1 |
| LaRochelle, WJ; Patel, BK; Pierce, JH | 1 |
| Claesson-Welsh, L; Heldin, CH; Hooshmand-Rad, R; Yokote, K | 1 |
| Thomas, GJ; Wen, ZQ | 1 |
| Braunstein, LD; Pang, J; Stanton, RC; Stuhlmeier, KM; Tian, WN; Tian, X; Xi, QC | 1 |
| Alber, F; Carloni, P; Folkers, G; Kuonen, O; Scapozza, L | 1 |
| Sekiguchi, J; Shuman, S | 1 |
| Cheng, K; Koland, JG; Vijapurkar, U | 1 |
| Barber, L; Davies, MG; Hagen, PO; Huynh, TT; Svendsen, E | 1 |
| Fanburg, BL; Gillis, CN; Lanzillo, J; Lee, SL; Wang, WW | 1 |
| Berti, A; Dello Sbarba, P; Paccagnini, A; Rigacci, S; Rovida, E | 1 |
| Annerén, C; Oberg-Welsh, C; Welsh, M | 1 |
| Betina, V; Lakatos, B; Simkovic, M; Varecka, L | 1 |
| Connolly, BA; Evans, SJ; Maughan, WN; Shipstone, EJ | 1 |
| Haruta, T; Hori, H; Ishihara, H; Ishiki, M; Kobayashi, M; Sasaoka, T; Wada, T | 1 |
| Brooks, DP; Hall, CS; Nambi, P; Parameswaran, N; Spielman, WS | 1 |
| Folkers, G; Marquez, VE; Perozzo, R; Pilger, B; Prota, A; Russ, P; Scapozza, L; Schulz, GE; Vogt, J; Wurth, C | 1 |
| Goi, K; Iijima, K; Inukai, T; Kagami, K; Nakazawa, S; Sato, H; Sugita, K; Tezuka, T; Uno, K | 1 |
| Burgin, AB | 1 |
| Chou, CT; Lair, TS; Lu, JY; Tsai, CY; Tsai, YY; Wu, TH; Yu, CL | 1 |
| Cambon, C; Lanier, S; Parini, A; Séguélas, MH; Vindis, C | 1 |
| Aertsen, A; Balzarini, J; Camarasa, MJ; De Clercq, E; Pelemans, H; Pérez-Pérez, MJ; San-Félix, A; Van Laethem, K; Vandamme, AM; Velázquez, S | 1 |
| Beier, I; Düsing, R; Sachinidis, A; Schmitz, U; Thömmes, K; Vetter, H; Wagner, W | 1 |
| Cacalano, NA; Johnston, JA; Sanden, D | 1 |
| Burns, KD; Chen, JK; Harris, RC; Zimpelmann, J | 1 |
| Bruhns, P; Daëron, M; Fridman, WH; Krystal, G; Malbec, O; Schmitt, C | 1 |
| Dorrestijn, J; Maassen, JA; Telting, D; van der Zon, GC | 1 |
| Hashimoto, H; Lau, KH | 1 |
| da Rocha, FA; de Brum-Fernandes, AJ | 1 |
| Awazu, M; Fujita, H; Hida, M; Omori, S | 1 |
| Colburn, MJ; Dong, Y; Fechner, J; Fernandez, LA; Hamawy, MM; Hu, H; Ishido, N; Kanmaz, T; Knechtle, SJ; Oberley, T; Schultz, J; Tae Kim, H; Torrealba, J; Tsuchida, M; Yagci, G | 1 |
| Friesel, R; Harkins, LK; Kovalenko, D; Nadeau, RJ; Yang, X | 1 |
| BRUECKNER, J; GERBAULET, K; MAURER, W | 1 |
| GOLDSTEIN, J | 1 |
| Hashimoto, N; Horiuchi, S; Makino, H; Saito, Y; Sano, H; Seki, N; Yagui, K | 1 |
| Clunn, GF; Fexby, SE; Gallagher, KL; Hughes, AD; Lymn, JS; Patel, MK | 1 |
| Balbis, A; Baquiran, G; Dumas, V; Posner, BI | 1 |
| Franco, S; Martínez, MA; Mas, A; Matamoros, T; Menéndez-Arias, L; Vázquez-Alvarez, BM | 1 |
| Agapova, LS; Chumakov, PM; Kopnin, BP; Volodina, JL | 1 |
| Fujimoto, J; Kotani, M; Motegi, A; Sakuraba, H; Yamamoto, T | 1 |
| Buricchi, F; Camici, G; Caselli, A; Chiarugi, P; Cirri, P; Giannoni, E; Manao, G; Paoli, P; Ramponi, G; Raugei, G; Taddei, ML | 1 |
| Amos, S; Hussaini, IM; Martin, PM; Parsons, SJ; Polar, GA | 1 |
| Arnqvist, HJ; Chisalita, SI | 1 |
| Meyer, RD; Mohammadi, M; Rahimi, N | 1 |
| Czernin, J; Hildebrandt, IJ; Phelps, ME; Su, H; Weber, WA; Wei, LH | 1 |
| Alauddin, MM; Flores, LG; Gelovani, JG; Mukhopadhyay, U; Shavrin, A; Soghomonyan, S; Volgin, AY; Yeh, HH | 1 |
| Chan, P; Wang, L; Xu, S; Xu, X | 1 |
| Chen, Y; Lan, T; Qu, R; Sang, J; Wu, Y | 1 |
| Carell, T; Heil, K; Kashiwazaki, G; Kneuttinger, AC | 1 |
| Barretta, ML; Cervigni, RI; Colanzi, A; Corda, D; D'Ambrosio, C; Scaloni, A; Spano, D | 1 |
| Garry, M; Groehler, A; Kren, S; Li, Q; Robledo-Villafane, M; Schmidt, J; Tretyakova, N | 1 |
| Ahn, HC; Cheong, C; Durai, P; Jeong, KW; Kim, EH; Kim, HJ; Kim, Y; Kwak, C; Lee, Y; Ryu, KS | 1 |
1 review(s) available for thymidine and tyrosine
| Article | Year |
|---|---|
Chemical and biological consequences of beta-decay. Part 1.
Topics: Bromodeoxyuridine; Carbon Radioisotopes; Cytosine; Deoxyuridine; Free Radicals; Idoxuridine; Iodine Radioisotopes; Isotope Labeling; Phenols; Phosphorus Radioisotopes; Radioactive Tracers; Radioactivity; Radioisotopes; Succinates; Sulfur Radioisotopes; Thymidine; Tritium; Tyrosine; Uracil | 1977 |
152 other study(ies) available for thymidine and tyrosine
| Article | Year |
|---|---|
Externally disposed plasma membrane proteins. II. Metabolic fate of iodinated polypeptides of mouse L cells.
Topics: Animals; Autoradiography; Cell Division; Cell Membrane; Iodides; Iodine Radioisotopes; Kinetics; L Cells; Latex; Lysosomes; Mice; Microspheres; Molecular Weight; Neoplasm Proteins; Peptides; Phagocytosis; Phosphoric Diester Hydrolases; Polystyrenes; Proteins; Temperature; Thymidine; Tritium; Tyrosine | 1975 |
Inhibition of human prostatic epithelial cell replication by cAMP and selected analogs.
Topics: Adenosine; Adenosine Monophosphate; Bucladesine; Cell Division; Cell Line; Cyclic AMP; Phosphodiesterase Inhibitors; Thymidine; Tyrosine; Uridine; Xanthines | 1976 |
Radioautographic studies on amelogenesis.
Topics: Ameloblasts; Amelogenesis; Animals; Autoradiography; Cell Differentiation; Cell Movement; Dental Enamel; Fucose; Glycoproteins; Incisor; Odontogenesis; Proline; Rats; Receptor, Insulin; Thymidine; Tritium; Tyrosine | 1979 |
Delayed hypersensitivity to mono-azobenzene-arsonate-N-acetyl-L-tyrosine. I. Induction of cellular sensitivity in the rat.
Topics: Animals; Azo Compounds; Cell Migration Inhibition; Freund's Adjuvant; Hemagglutination Tests; Hypersensitivity, Delayed; Lymph Nodes; Lymphocyte Activation; Lymphocytes; Male; p-Azobenzenearsonate; Rats; Rats, Inbred Strains; Skin Tests; Thymidine; Tyrosine | 1975 |
Delayed hypersensitivity to mono-azobenzene arsonate-N-acetyl-L-tyrosine. II. An operational model in the mouse.
Topics: Animals; Azo Compounds; Dose-Response Relationship, Drug; Freund's Adjuvant; Hypersensitivity, Delayed; Immunity, Cellular; Lymphocyte Activation; Lymphocytes; Mice; Mice, Inbred BALB C; Skin Tests; Thymidine; Time Factors; Tyrosine | 1975 |
The role of insulin receptor kinase domain autophosphorylation in receptor-mediated activities. Analysis with insulin and anti-receptor antibodies.
Topics: Animals; Antibodies; CHO Cells; Cricetinae; Cricetulus; DNA; Electrophoresis, Polyacrylamide Gel; Glucose; Glycogen; Humans; Insulin; Mutagenesis, Site-Directed; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Receptor, Insulin; Thymidine; Transfection; Tyrosine | 1992 |
The platelet-derived growth factor beta-receptor kinase insert confers specific signaling properties to a chimeric fibroblast growth factor receptor.
Topics: Amino Acid Sequence; Chimera; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Fibroblast Growth Factors; Humans; Molecular Sequence Data; Phosphorylation; Protein Kinases; Receptors, Cell Surface; Receptors, Fibroblast Growth Factor; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Substrate Specificity; Thymidine; Tyrosine | 1992 |
The insulin receptor-related receptor. Tissue expression, ligand binding specificity, and signaling capabilities.
Topics: 1-Phosphatidylinositol 4-Kinase; Animals; Base Sequence; Blotting, Northern; Blotting, Western; Cells, Cultured; CHO Cells; Cricetinae; Deoxyglucose; DNA; GTPase-Activating Proteins; Insulin; Molecular Sequence Data; Phosphorylation; Phosphotransferases; Polymerase Chain Reaction; Precipitin Tests; Proteins; Receptor, Insulin; Signal Transduction; Substrate Specificity; Thymidine; Tissue Distribution; Tyrosine | 1992 |
Monoclonal antibodies against the extracellular domain of the erbB-2 receptor function as partial ligand agonists.
Topics: Antibodies, Monoclonal; Blotting, Western; Breast Neoplasms; Flow Cytometry; Humans; Ligands; Phosphorylation; Precipitin Tests; Proto-Oncogene Proteins; Proto-Oncogenes; Receptor, ErbB-2; Thymidine; Tumor Cells, Cultured; Tunicamycin; Tyrosine | 1992 |
Signal transduction by the epidermal growth factor receptor is attenuated by a COOH-terminal domain serine phosphorylation site.
Topics: Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; CHO Cells; Cricetinae; DNA Replication; Epidermal Growth Factor; ErbB Receptors; Humans; Kinetics; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Peptides; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Serine; Signal Transduction; Substrate Specificity; Thymidine; Transfection; Tyrosine | 1992 |
Activation of phosphatidylinositol 3-kinase by epidermal growth factor, basic fibroblast growth factor, and nerve growth factor in PC12 pheochromocytoma cells.
Topics: Animals; Cell Division; Enzyme Activation; Epidermal Growth Factor; Fibroblast Growth Factor 2; Kinetics; Liver; Mitogens; Nerve Growth Factors; PC12 Cells; Phosphatidylinositol 3-Kinases; Phosphotransferases; Phosphotyrosine; Rats; Thymidine; Tyrosine | 1992 |
Biphasic activation of two mitogen-activated protein kinases during the cell cycle in mammalian cells.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; CDC2 Protein Kinase; Cell Cycle; CHO Cells; Cricetinae; Enzyme Activation; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Nocodazole; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Threonine; Thymidine; Tyrosine | 1992 |
Photoreactions of thymine and thymidine with N-acetyltyrosine.
Topics: DNA-Binding Proteins; Hydrolysis; Magnetic Resonance Spectroscopy; Photochemistry; Thymidine; Thymine; Tyrosine | 1992 |
Evidence for a lack of functional receptors for nerve growth factor (NGF) in chick bone cells in vitro.
Topics: Alkaline Phosphatase; Animals; Cell Line; Cells, Cultured; Chickens; Nerve Growth Factors; Phosphorylation; Receptors, Nerve Growth Factor; Skull; Thymidine; Tyrosine | 1992 |
PDGF induces tyrosine phosphorylation in osteoblast-like cells: relevance to mitogenesis.
Topics: Animals; Cell Line; Genistein; Isoflavones; Mitosis; Osteoblasts; Phosphorylation; Platelet-Derived Growth Factor; Thymidine; Tyrosine; Vanadates | 1992 |
Cell type-specific tyrosine phosphorylation of IL-2 receptor beta chain in response to IL-2.
Topics: Cell Division; Cell Line; Electrophoresis, Gel, Two-Dimensional; Humans; Interleukin-2; Phosphorylation; Precipitin Tests; Receptors, Interleukin-2; Thymidine; Transfection; Tumor Cells, Cultured; Tyrosine | 1992 |
Intracellular signaling by a mutant human insulin receptor lacking the carboxyl-terminal tyrosine autophosphorylation sites.
Topics: Animals; Cell Line; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Glucose; Glycogen; Insulin; Insulin-Like Growth Factor I; Mutation; Phosphorylation; Protein Kinases; Rats; Receptor, Insulin; Ribosomal Protein S6 Kinases; Signal Transduction; Thymidine; Transfection; Tyrosine | 1992 |
Enhanced insulin-induced mitogenesis and mitogen-activated protein kinase activities in mutant insulin receptors with substitution of two COOH-terminal tyrosine autophosphorylation sites by phenylalanine.
Topics: Animals; Antigen-Antibody Complex; Base Sequence; CHO Cells; Cricetinae; Deoxyglucose; DNA; Endocytosis; Enzyme Activation; Growth Substances; Immunoblotting; Insulin; Lectins; Molecular Sequence Data; Mutation; Phenylalanine; Phosphorylation; Precipitin Tests; Protein Kinases; Receptor, Insulin; Solubility; Thymidine; Transfection; Tyrosine | 1992 |
The insulin receptor functions normally in Chinese hamster ovary cells after truncation of the C terminus.
Topics: 1-Phosphatidylinositol 4-Kinase; Animals; Autoradiography; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Electrophoresis, Polyacrylamide Gel; Female; Glycogen; Humans; Mutation; Ovary; Peptide Mapping; Phosphorylation; Phosphotransferases; Receptor, Insulin; Thymidine; Trypsin; Tyrosine | 1991 |
Analysis of platelet-derived growth factor receptor domain function using a novel chimeric receptor approach.
Topics: Amino Acid Sequence; Base Sequence; Calcium; Cell Line; Chimera; DNA; Epidermal Growth Factor; Humans; Hydrogen-Ion Concentration; Ligands; Molecular Sequence Data; Phosphorylation; Platelet-Derived Growth Factor; Precipitin Tests; Receptors, Cell Surface; Receptors, Platelet-Derived Growth Factor; Thymidine; Transfection; Tyrosine | 1991 |
Regulation of biological functions by an insulin receptor monoclonal antibody in insulin receptor beta-subunit mutants.
Topics: Aminoisobutyric Acids; Animals; Antibodies, Monoclonal; Binding Sites; Cell Line; Cricetinae; Cricetulus; Enzyme Activation; Female; Humans; Mutation; Phosphorylation; Protein-Tyrosine Kinases; Receptor, Insulin; Signal Transduction; Thymidine; Tyrosine | 1992 |
Phorbol 12-myristate 13-acetate inhibits granulocyte-macrophage colony stimulating factor-induced protein tyrosine phosphorylation in a human factor-dependent hematopoietic cell line.
Topics: Cell Line; DNA Replication; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Interleukin-3; Kinetics; Phosphoprotein Phosphatases; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Thymidine; Tyrosine; Vanadates | 1991 |
Transmembrane signalling by insulin via an insulin receptor mutated at tyrosines 1158, 1162, and 1163.
Topics: Aminoisobutyric Acids; Animals; Gene Expression; Insulin; Mutagenesis, Site-Directed; Phenylalanine; Phosphorylation; Protein-Tyrosine Kinases; Rats; Receptor, Insulin; Signal Transduction; Thymidine; Transfection; Tumor Cells, Cultured; Tyrosine | 1991 |
Effect of glucose and branched chain amino acid (BCAA) infusion on onset of liver regeneration and plasma amino acid pattern in partially hepatectomized rats.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Cell Division; DNA; Glucose; Hepatectomy; Infusions, Intravenous; Liver; Liver Regeneration; Phenylalanine; Rats; Rats, Inbred Strains; Thymidine; Tyrosine | 1991 |
Effects of simvastatin (MK-733) on branched pathway of mevalonate.
Topics: Animals; Anticholesteremic Agents; Cell Line; Cholesterol; DNA; Dolichols; Humans; Liver Neoplasms, Experimental; Lovastatin; Mevalonic Acid; Proteins; Simvastatin; Thymidine; Tumor Cells, Cultured; Tyrosine; Ubiquinone | 1990 |
Studies of antiproteolytic effects of glyburide on rat L6 myoblasts: comparisons with insulin.
Topics: Administration, Oral; Animals; Cell Line; DNA; Dose-Response Relationship, Drug; Glyburide; Hydrolysis; Insulin; Muscle Proteins; Muscles; Rats; Thymidine; Tyrosine | 1990 |
Interleukin 2-induced tyrosine phosphorylation. Interleukin 2 receptor beta is tyrosine phosphorylated.
Topics: Amino Acids; Antibodies; Cell Line; DNA Replication; Humans; Interleukin-2; Killer Cells, Natural; Kinetics; Phosphorylation; Phytohemagglutinins; Receptors, Interleukin-2; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thymidine; Tyrosine | 1990 |
Schistosoma mansoni: nucleic acid synthesis in immature females from single-sex infections, paired in vitro with intact males and male segments.
Topics: Animals; DNA; Female; Male; Nucleic Acid Hybridization; Protein Biosynthesis; RNA, Messenger; Schistosoma mansoni; Sex Factors; Thymidine; Tyrosine | 1988 |
Formation of radiation-induced cross-links between thymine and tyrosine: possible model for cross-linking of DNA and proteins by ionizing radiation.
Topics: Chromatography, Gas; DNA; Gas Chromatography-Mass Spectrometry; Models, Biological; Proteins; Thymidine; Thymidine Monophosphate; Thymine; Tyrosine; Uracil | 1985 |
A kinetic study of DNA and basic protein metabolism during spermatogenesis in the sand crab, Emerita analoga.
Topics: Animals; Autoradiography; Brachyura; Cell Nucleus; DNA; Histones; Kinetics; Lysine; Male; Nucleoproteins; Protamines; Spectrophotometry; Spermatogenesis; Spermatozoa; Staining and Labeling; Testis; Thymidine; Time Factors; Tritium; Tyrosine | 1972 |
Uptake of amino acids and nucleic acid precursors by regenerating rat liver.
Topics: Adenine; Adrenalectomy; Amino Acids; Animals; Dactinomycin; Hepatectomy; Liver; Liver Regeneration; Lysine; Male; Ornithine; Orotic Acid; Phenylalanine; Rats; RNA; Thymidine; Tritium; Tyrosine; Uridine; Valine | 1972 |
Envelope protein alterations in a conditional mutant of Klebsiella pneumoniae with pH dependent morphology and temperature dependent division.
Topics: Bacterial Proteins; Cell Division; Cell Wall; Densitometry; DNA; Hydrogen-Ion Concentration; Kinetics; Klebsiella pneumoniae; Leucine; Molecular Weight; Mutation; RNA; Staining and Labeling; Temperature; Thymidine; Tyrosine; Uridine | 1974 |
An electrophoretic difference between surface and secreted IgM of murine splenocytes.
Topics: Animals; Cell Membrane; Electrophoresis, Polyacrylamide Gel; Immunodiffusion; Immunoglobulin M; Mice; Mice, Inbred BALB C; Spleen; Thymidine; Tritium; Tyrosine | 1973 |
Inhibition of DNA and protein synthesis in melanocytes by a melanoma extract.
Topics: Animals; Carbon Radioisotopes; Catechol Oxidase; Cell Line; Cells, Cultured; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry; Chromatography; Chromatography, Gel; DNA; Electrophoresis, Polyacrylamide Gel; Epinephrine; Hydrocortisone; In Vitro Techniques; Leucine; Melanocytes; Melanoma; Mice; Molecular Weight; Protein Biosynthesis; Thymidine; Time Factors; Tritium; Tyrosine | 1974 |
Peripheral and thoracic duct lymphocyte blastogenesis by T cell specific mitogens in the rhesus monkey.
Topics: Aniline Compounds; Animals; Arsenicals; Autoradiography; Cell Separation; Chyle; Drainage; Freund's Adjuvant; Haplorhini; Immunization; Immunodiffusion; Injections, Intradermal; Injections, Subcutaneous; Lectins; Lymphocyte Activation; Macaca; Mitogens; Serum Albumin, Bovine; T-Lymphocytes; Thoracic Duct; Thymidine; Tritium; Tyrosine | 1973 |
Physiological differences between cyclopropane fatty acid-deficient mutants and the parent strain of Streptococcus faecalis.
Topics: Cell Division; Cell Survival; Chromatography, Thin Layer; Cyclopropanes; Deoxycholic Acid; Drug Resistance, Microbial; Enterococcus faecalis; Fatty Acids; Folic Acid; Hydrogen-Ion Concentration; Kinetics; Methotrexate; Mutation; Pantothenic Acid; Sodium Chloride; Species Specificity; Temperature; Thymidine; Time Factors; Tyrosine | 1974 |
Antigen recognition and the immune response: the capacity of L-tyrosine-azobenzenearsonate to serve as a carrier for a macromolecular hapten.
Topics: Aminocaproates; Animals; Antibody Formation; Antibody Specificity; Arsenicals; Arthus Reaction; Azo Compounds; Bacillus anthracis; Benzene Derivatives; Culture Techniques; DNA; Glutamates; Guinea Pigs; Haptens; Hypersensitivity, Delayed; Immunization, Secondary; Lymph Nodes; Lymphocytes; Molecular Weight; Precipitin Tests; Skin Tests; Spleen; Thymidine; Tritium; Tyrosine | 1971 |
Mode of action of streptolydigin.
Topics: Anti-Bacterial Agents; Bacillus megaterium; Bacterial Proteins; Carbon Isotopes; Diphosphates; Nucleotides; Rifampin; RNA Nucleotidyltransferases; Thymidine; Tritium; Tyrosine; Uracil | 1969 |
Metabolic and virologic studies in primate liver organ cultures.
Topics: Animals; Autoradiography; Centrifugation, Density Gradient; Culture Techniques; DNA; Enterovirus; Haplorhini; Herpesviridae; Interferons; Leucine; Liver; Organ Culture Techniques; Orthomyxoviridae; Proline; Protein Biosynthesis; RNA; Thymidine; Tritium; Tyrosine; Uridine; Virus Replication | 1970 |
Alloantiserum-mediated suppression of histocompatibility-linked IR gene controlled immune responses. I. Histocompatibility antigen requirement.
Topics: Alanine; Animals; Antigens; Ascitic Fluid; Chromium Radioisotopes; Cytotoxicity Tests, Immunologic; Dinitrophenols; DNA; Glutamates; Guinea Pigs; Histocompatibility Antigens; Immune Sera; Immunization; Immunogenetics; Immunosuppression Therapy; Isoantibodies; Lectins; Lymphocyte Activation; Lymphocytes; Lysine; Skin Tests; Species Specificity; Thymidine; Tritium; Tyrosine | 1974 |
[DNA replication in polytene chromosomes. II. An autoradiographic study of H3-thymidine incorporation into salivary gland cells of Drosophilia virilis larvae during suppression of protein synthesis by cycloheximide].
Topics: Animals; Autoradiography; Chromosomes; Cycloheximide; Depression, Chemical; DNA Replication; Drosophila; Larva; Thymidine; Time Factors; Tritium; Tyrosine | 1974 |
The effects of phenylalanine ammonia-lyase on leukemic lymphocytes in vitro.
Topics: Animals; Cells, Cultured; Cinnamates; Deamination; Depression, Chemical; DNA, Neoplasm; Humans; In Vitro Techniques; Leukemia, Lymphoid; Lyases; Lymphocytes; Mice; Phenylalanine; Thymidine; Tritium; Tyrosine | 1972 |
Inhibition of in vitro lymphocyte proliferation by alloantisera in genetically controlled immune systems in guinea pigs.
Topics: Animals; Antibodies, Anti-Idiotypic; Ascitic Fluid; B-Lymphocytes; Binding Sites, Antibody; Cells, Cultured; Dinitrophenols; Genetic Linkage; Glutamates; Guinea Pigs; Hemadsorption; Histocompatibility Antigens; Immune Sera; Immunogenetics; Lymphocyte Activation; Lysine; T-Lymphocytes; Thymidine; Tritium; Tyrosine | 1973 |
Observations on ligated adults of Philophthalmus megalurus, Gorgoderina attenuata, and Megalodiscus and autoradiography.
Topics: Animals; Autoradiography; Chickens; Leucine; Ligation; Microscopy, Electron, Scanning; Rana pipiens; Thymidine; Trematoda; Tritium; Tyrosine | 1974 |
A possible role for histone in the synthesis of DNA.
Topics: Acrylates; Animals; Canavanine; Centrifugation, Density Gradient; Chickens; Cycloheximide; Cytarabine; Dactinomycin; DNA; DNA Replication; Erythrocytes; Histones; Indoles; Kinetics; Leucine; Peptide Elongation Factors; Thymidine; Tritium; Tryptophan; Tyrosine; Uridine | 1972 |
Infection of Escherichia coli envelope-membrane complex with lambda phage: adsorption and penetration.
Topics: Adsorption; Antigen-Antibody Reactions; Binding Sites; Carbon Radioisotopes; Cell Fractionation; Cell Membrane; Cell Wall; Centrifugation, Density Gradient; Coliphages; Deoxyribonucleases; DNA, Viral; Escherichia coli; Isotope Labeling; Microscopy, Electron; Thymidine; Time Factors; Tritium; Tyrosine; Viral Plaque Assay | 1973 |
Nucleotide modification in vitro of the precursor of transfer RNA of Escherichia coli.
Topics: Adenosine; Alkenes; Base Sequence; Escherichia coli; Pseudouridine; Ribonucleases; Ribonucleosides; Ribonucleotides; RNA, Bacterial; RNA, Transfer; Thymidine; tRNA Methyltransferases; Tyrosine; Uridine | 1973 |
Bacteriophage f1 infection: fate of the parental major coat protein.
Topics: Carbon Radioisotopes; Cell Membrane; Centrifugation, Density Gradient; Coliphages; Cyanides; DNA, Viral; Escherichia coli; Lysine; Peroxidases; Potassium Iodide; Thymidine; Tritium; Tyrosine; Viral Proteins | 1974 |
Megalodiscus temperatus: absorption and incorporation of tritiated tyrosine, thymidine, and adenosine.
Topics: Adenosine; Animals; Autoradiography; Culture Media; Ecology; Escherichia coli; Female; Histocytochemistry; Male; Rana pipiens; Thymidine; Trematoda; Tritium; Tyrosine | 1974 |
Delayed hypersensitivity to azobenzenearsonate amino acids conjugates. In vitro study of the specificity of the immune response by 3 H-thymidine incorporation into lymph node cells.
Topics: Animals; Antigens; Arsenicals; Azo Compounds; Benzene; Cross Reactions; Guinea Pigs; Histidine; Hypersensitivity, Delayed; Lymphocyte Activation; Serum Albumin; Skin Tests; Thymidine; Tritium; Tryptophan; Tyrosine | 1972 |
Gorgoderina attenuata: uptake and incorporation of tyrosine, thymidine, and adenosine.
Topics: Absorption; Adenosine; Animals; Autoradiography; Female; Gonads; Intestinal Mucosa; Male; Ovum; Radionuclide Imaging; Stereoisomerism; Thymidine; Trematoda; Tritium; Tyrosine | 1973 |
Autoradiographic studies on the reproductive system of Philophthalmus hegeneri Penner and Fried, 1963.
Topics: Animals; Autoradiography; Chickens; Female; Genitalia; Insemination; Male; Ovary; Ovum; Reproduction; Snails; Spermatogenesis; Testis; Thymidine; Trematoda; Tritium; Tyrosine | 1973 |
The interaction of the lanthanide ions with staphylococcal nuclease.
Topics: Binding Sites; Binding, Competitive; Calcium; Chlorides; Deoxyribonucleases; Dextrans; Drug Stability; Dysprosium; Gadolinium; Kinetics; Lanthanum; Ligands; Mathematics; Metals; Neodymium; Nucleoside Diphosphate Sugars; Praseodymium; Spectrophotometry; Spectrophotometry, Ultraviolet; Staphylococcus; Thymidine; Trypsin; Tyrosine; Ytterbium | 1973 |
The action of concanavalin A on migrating and differentiating neural crest cells.
Topics: Ambystoma; Animals; Autoradiography; Binding Sites; Cell Differentiation; Cell Membrane; Cell Movement; Concanavalin A; DNA; Female; Ganglia; Leucine; Microscopy, Electron; Morphogenesis; Nervous System; Protein Biosynthesis; Thymidine; Time Factors; Tritium; Tyrosine | 1974 |
Proliferation and differentiation of pigment cells in vitro.
Topics: Animals; Carbon Isotopes; Cell Count; Cell Differentiation; Cell Division; Cell Line; Chromatophores; Clone Cells; Culture Techniques; Cycloheximide; DNA; Melanins; Melanoma; Mice; Microscopy; Microscopy, Phase-Contrast; Protein Biosynthesis; Thymidine; Tritium; Tyrosine | 1970 |
Specific immune response genes of the guinea pig. V. Influence of the GA and GT immune response genes on the specificity of cellular and humoral immune responses to a terpolymer of L-glutamic acid, L-alanine, and L-tyrosine.
Topics: Alanine; Animals; Antibody Formation; Antibody Specificity; Cells, Cultured; Cross Reactions; Genes; Glutamates; Guinea Pigs; Histocompatibility; Hypersensitivity, Delayed; Immune Sera; Immunity; Immunity, Cellular; Immunization; Immunogenetics; Iodine Isotopes; Lymph Nodes; Polymers; Skin Tests; Thymidine; Tritium; Tyrosine | 1972 |
Delayed hypersensitivity to azobenzenearsonate-N-acetyl-L-tyrosine. In vivo and in vitro study.
Topics: Animals; Antibodies; Antigens; Arsenicals; Cattle; Cell Migration Inhibition; Erythrocytes; Guinea Pigs; Hemagglutination Tests; Hypersensitivity, Delayed; Lymph Nodes; Lymphocyte Activation; Macrophages; p-Azobenzenearsonate; Passive Cutaneous Anaphylaxis; Serum Albumin; Serum Albumin, Bovine; Skin; Tannins; Thymidine; Tritium; Tyrosine | 1971 |
Interactions of tyrosine and tyramine with nucleic acids and their components. Fluorescence, nuclear magnetic resonance and circular dichroism studies.
Topics: Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Animals; Cattle; Circular Dichroism; Cold Temperature; Cytidine; Cytosine Nucleotides; DNA; Ethers; Fluorometry; Guanine Nucleotides; Magnetic Resonance Spectroscopy; Mathematics; Nucleic Acid Conformation; Phenylalanine; Polynucleotides; Serotonin; Sodium Chloride; Temperature; Thymidine; Thymus Gland; Tyramine; Tyrosine; Ultraviolet Rays | 1971 |
DNA, RNA, and protein synthesis of pigment cells in culture.
Topics: Animals; Autoradiography; Chromatophores; Culture Techniques; DNA; Leucine; Melanins; Melanoma; Mice; Neoplasms, Experimental; Pigmentation; Protein Biosynthesis; Puromycin; RNA; Skin; Skin Neoplasms; Thymidine; Tritium; Tyrosine; Uridine | 1970 |
Chromosomal control of foot pad development in Sarcophaga bullata. II. Cuticle formation and tanning.
Topics: Animals; Carbon Isotopes; Chitin; Chromosomes; Culture Techniques; Densitometry; Diptera; DNA; Glucose; Leucine; Male; Metamorphosis, Biological; Phenylalanine; Pigmentation; Polysaccharides; Protein Biosynthesis; Skin; Spectrophotometry; Thymidine; Tritium; Tyrosine | 1970 |
[Specific cell functions of cell and tissue cultures. II. Control of melanin synthesis in cell cultures of the Harding-Passey melanoma].
Topics: Animals; Carbon Isotopes; Culture Techniques; Depression, Chemical; Dihydroxyphenylalanine; Leucine; Melanins; Melanoma; Mice; Phenylthiourea; Thymidine; Tyrosine | 1970 |
Uptake and incorporation of glucose, tyrosine, leucine, and thymidine by adult Philophthalmus megalurus (Cort, 1914) (Trematoda), as determined by autoradiography.
Topics: Animals; Autoradiography; Birds; Culture Media; Freeze Drying; Glucose; Glycogen; Histocytochemistry; Leucine; Thymidine; Trematoda; Tritium; Tyrosine | 1968 |
Control of self-irradiation decomposition of tritium-labelled compounds at high specific activity.
Topics: Alcohols; Drug Stability; Ethanol; Folic Acid; Formates; Histidine; Leucine; Methotrexate; Nucleosides; Penicillin G; Radiation-Protective Agents; Thymidine; Tritium; Tyrosine; Uridine | 1966 |
Effect of methyl methanesulfonate on macromolecular biosynthesis in P388F cells.
Topics: Alanine; Animals; Culture Techniques; DNA, Neoplasm; Glycine; Lymphoma; Mice; Neoplasm Proteins; Neoplasms, Experimental; RNA, Neoplasm; Sulfonic Acids; Thymidine; Tritium; Tyrosine | 1967 |
The use of capillary gas chromatography-mass spectrometry for identification of radiation-induced DNA base damage and DNA base-amino acid cross-links.
Topics: Amino Acids; Base Composition; Chemical Phenomena; Chemistry; Chromatography, Gas; Cytosine; Deoxycytidine; DNA; Formates; Gamma Rays; Gas Chromatography-Mass Spectrometry; Hydrochloric Acid; Hydrolysis; Thymidine; Thymidine Monophosphate; Thymine; Tyrosine | 1984 |
Okadaic acid blocks PDGF-induced proliferation of AKR-2B fibroblasts at the transition from G1- to S-phase.
Topics: Animals; Becaplermin; Cell Cycle; Cell Division; Cell Line; DNA; Dose-Response Relationship, Drug; Ethers, Cyclic; Fibroblasts; G1 Phase; Inositol Phosphates; Kinetics; Mice; Mice, Inbred AKR; Okadaic Acid; Phosphotyrosine; Platelet-Derived Growth Factor; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-sis; Recombinant Proteins; S Phase; Signal Transduction; Thymidine; Tyrosine | 1994 |
Angiotensin II induces delayed mitogenesis and cellular proliferation in rat aortic smooth muscle cells. Correlation with the expression of specific endogenous growth factors and reversal by suramin.
Topics: 3T3 Cells; Angiotensin II; Animals; Antibodies; Aorta; Becaplermin; Cell Division; Culture Media, Conditioned; DNA; Dose-Response Relationship, Drug; Genes, fos; Growth Substances; Kinetics; Mice; Mitogens; Muscle, Smooth, Vascular; Phosphoproteins; Phosphotyrosine; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Suramin; Thymidine; Tyrosine | 1994 |
Preferential inhibition of platelet-derived growth factor-stimulated DNA synthesis and protein tyrosine phosphorylation by nordihydroguaiaretic acid.
Topics: 3T3 Cells; Animals; Arachidonic Acid; Cell Line; Cell Nucleus; Cells, Cultured; Dinoprostone; DNA; Epidermal Growth Factor; Fibroblasts; Humans; Insulin; Masoprocol; Mice; Phosphoproteins; Phosphorylation; Phosphotyrosine; Platelet-Derived Growth Factor; Rats; Skin; Thymidine; Tyrosine | 1994 |
Independent effects of platelet-derived growth factor isoforms on mitogen-activated protein kinase activation and mitogenesis in human dermal fibroblasts.
Topics: Adult; Becaplermin; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; DNA; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Fibroblasts; Humans; Immunoblotting; Kinetics; Phosphoproteins; Phosphotyrosine; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Recombinant Proteins; Skin; Thymidine; Tyrosine | 1994 |
Tyrosine phosphorylation of Shc is induced by IL-3, IL-5 and GM-CSF.
Topics: Animals; Blotting, Western; Cell Division; Cell Line; Enzyme Induction; Granulocyte-Macrophage Colony-Stimulating Factor; Interleukin-3; Interleukin-5; Kinetics; Mice; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Recombinant Proteins; Sequence Homology, Amino Acid; Thymidine; Tyrosine | 1994 |
Insulin and insulin-like growth factor-I receptors similarly stimulate deoxyribonucleic acid synthesis despite differences in cellular protein tyrosine phosphorylation.
Topics: 1-Phosphatidylinositol 4-Kinase; 3T3 Cells; Animals; Cell Line; DNA; Enzyme Activation; Fibroblasts; Insulin; Insulin-Like Growth Factor I; Mice; Mitogen-Activated Protein Kinase 1; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Precipitin Tests; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptor, IGF Type 1; Receptor, Insulin; Thymidine; Tyrosine | 1994 |
p210 bcr-abl confers overexpression of inosine monophosphate dehydrogenase: an intrinsic pathway to drug resistance mediated by oncogene.
Topics: Animals; Antineoplastic Agents; Blotting, Northern; Cell Division; Cell Line, Transformed; DNA Replication; Drug Resistance; Fusion Proteins, bcr-abl; Gene Expression; IMP Dehydrogenase; Mice; Oncogenes; Phosphoproteins; Phosphotyrosine; Poly A; Ribavirin; RNA; RNA, Messenger; Thymidine; Tyrosine | 1994 |
Heregulin stimulates mitogenesis and phosphatidylinositol 3-kinase in mouse fibroblasts transfected with erbB2/neu and erbB3.
Topics: 3T3 Cells; Animals; Carrier Proteins; Cell Division; Culture Media, Serum-Free; Dexamethasone; ErbB Receptors; Fibroblasts; Glycoproteins; Growth Substances; Mice; Neuregulin-1; Peptide Fragments; Phosphorylation; Phosphotyrosine; Platelet-Derived Growth Factor; Proto-Oncogene Proteins; Receptor, ErbB-2; Receptor, ErbB-3; Recombinant Proteins; Thymidine; Transfection; Tyrosine | 1995 |
Demonstration of functionally different interactions between phospholipase C-gamma and the two types of platelet-derived growth factor receptors.
Topics: Amino Acid Sequence; Animals; Aorta; Base Sequence; Becaplermin; Binding, Competitive; Cell Division; Endothelium, Vascular; Isoenzymes; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Peptide Fragments; Phospholipases; Phosphopeptides; Phosphorylation; Phosphotyrosine; Platelet-Derived Growth Factor; Point Mutation; Proto-Oncogene Proteins c-sis; Receptor Protein-Tyrosine Kinases; Receptor, Platelet-Derived Growth Factor alpha; Receptor, Platelet-Derived Growth Factor beta; Receptors, Platelet-Derived Growth Factor; Recombinant Proteins; Sequence Homology, Amino Acid; Swine; Thymidine; Tyrosine | 1995 |
Amiloride suppresses erythropoietin-induced proliferation and MAP kinase, but potentiates differentiation of J2E cells.
Topics: Amiloride; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cell Division; Cell Line; Dose-Response Relationship, Drug; Drug Synergism; Erythrocytes; Erythropoietin; Genistein; Hemoglobins; Humans; Immunoblotting; Isoflavones; Kinetics; Leucine; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Recombinant Proteins; Thymidine; Tyrosine | 1995 |
Increased intracellular cyclic AMP levels suppress the mitogenic responses of human astrocytoma cells to growth factors.
Topics: Astrocytoma; Blotting, Western; Brain Neoplasms; Bucladesine; Cell Division; Cyclic AMP; Glial Fibrillary Acidic Protein; Growth Substances; Humans; Immunohistochemistry; Mitogens; Phosphorylation; Receptor Protein-Tyrosine Kinases; Thymidine; Tumor Cells, Cultured; Tyrosine | 1995 |
Basic fibroblast growth factor is a neurotropic factor in GT1 gonadotropin-releasing hormone neuronal cell lines.
Topics: Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Fibroblast Growth Factor 2; Gonadotropin-Releasing Hormone; Mice; Mitogen-Activated Protein Kinase 1; Neurites; Neurons; Phosphorylation; Protein-Tyrosine Kinases; RNA, Messenger; Thymidine; Tritium; Tyrosine | 1995 |
Tyrosine 807 of the v-Fms oncogene product controls cell morphology and association with p120RasGAP.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Cell Transformation, Neoplastic; DNA Replication; Genes, fms; Glutathione Transferase; GTPase-Activating Proteins; Kinetics; Mice; Oncogene Protein gp140(v-fms); Oncogenes; Phenylalanine; Plasmids; Point Mutation; Protein-Tyrosine Kinases; Proteins; ras GTPase-Activating Proteins; Recombinant Fusion Proteins; Sarcoma Viruses, Feline; Thymidine; Transfection; Tyrosine | 1995 |
Murine T-lymphocyte proliferation induced by interleukin 2 correlates with a transient increase in p56lck kinase activity and the tyrosine phosphorylation of a 97-kDa protein.
Topics: Animals; Blotting, Northern; Dose-Response Relationship, Drug; Enzyme Activation; Genes, myc; Genistein; Humans; Interleukin-2; Isoflavones; Kinetics; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Male; Mice; Mice, Inbred C57BL; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Recombinant Proteins; RNA, Messenger; RNA, Ribosomal, 18S; T-Lymphocytes; Thymidine; Tyrosine | 1993 |
Common elements in interleukin 4 and insulin signaling pathways in factor-dependent hematopoietic cells.
Topics: Animals; Blood Cells; Cell Division; Cell Line; CHO Cells; Cricetinae; Culture Media, Serum-Free; DNA Replication; Electrophoresis, Polyacrylamide Gel; Insulin; Insulin-Like Growth Factor I; Interleukin-3; Interleukin-4; Kinetics; Mice; Peptide Mapping; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphotransferases; Phosphotyrosine; Receptor, Insulin; Recombinant Proteins; Signal Transduction; Thymidine; Transfection; Tyrosine | 1993 |
Tyrphostin inhibits bombesin stimulation of tyrosine phosphorylation, c-fos expression, and DNA synthesis in Swiss 3T3 cells.
Topics: 3T3 Cells; Animals; Bombesin; Calcium; Catechols; DNA; DNA Replication; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Gastrin-Releasing Peptide; Gene Expression; Genes, fos; Intracellular Signaling Peptides and Proteins; Kinetics; Membrane Proteins; Mice; Molecular Weight; Myristoylated Alanine-Rich C Kinase Substrate; Nitriles; Peptides; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proteins; Receptors, Cholecystokinin; Thymidine; Tyrosine; Tyrphostins | 1993 |
Oncostatin-M stimulates tyrosine protein phosphorylation in parallel with the activation of p42MAPK/ERK-2 in Kaposi's cells. Evidence that this pathway is important in Kaposi cell growth.
Topics: Acquired Immunodeficiency Syndrome; Benzoquinones; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cell Membrane; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Endothelium, Vascular; Enzyme Activation; Growth Inhibitors; Humans; Kinetics; Lactams, Macrocyclic; Mitogen-Activated Protein Kinase 1; Oncostatin M; Peptides; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Quinones; Sarcoma, Kaposi; Thymidine; Tumor Cells, Cultured; Tyrosine; Umbilical Veins | 1993 |
Comparison of effects of platelet-derived growth factor isoforms on signaling and DNA synthesis of human cultured saphenous vein cells.
Topics: Blotting, Western; Calcium; Cells, Cultured; DNA; Humans; Isomerism; Muscle, Smooth, Vascular; Phosphorylation; Platelet-Derived Growth Factor; Saphenous Vein; Signal Transduction; Thymidine; Tyrosine | 1995 |
Mutation of a conserved amino acid residue (tryptophan 1173) in the tyrosine kinase domain of the IGF-I receptor abolishes autophosphorylation but does not eliminate biologic function.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Conserved Sequence; Deoxyglucose; DNA Primers; Mice; Molecular Sequence Data; Mutation; Phosphorylation; Protein-Tyrosine Kinases; Receptors, Somatomedin; Signal Transduction; Thymidine; Tryptophan; Tyrosine; Wheat Germ Agglutinins | 1995 |
D2 dopamine receptor stimulation of mitogenesis in transfected Chinese hamster ovary cells: relationship to dopamine stimulation of tyrosine phosphorylations.
Topics: Animals; Arachidonic Acid; Cell Division; CHO Cells; Cricetinae; Cyclic AMP; Dopamine; Dopamine Agents; Mitogens; Phosphorylation; Rats; Receptors, Dopamine D2; Signal Transduction; Stimulation, Chemical; Thymidine; Transfection; Tritium; Tyrosine | 1993 |
Transforming growth factor-alpha increases tyrosine phosphorylation of microtubule-associated protein kinase in a small intestinal crypt cell line (IEC-6).
Topics: Animals; Antibodies, Monoclonal; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Catechols; Cell Line; Chemical Fractionation; Cytosol; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Genistein; Growth Inhibitors; Intestine, Small; Isoflavones; Molecular Weight; Nitriles; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Rats; Thymidine; Transforming Growth Factor alpha; Tyrosine; Tyrphostins | 1994 |
Prostaglandin F2 alpha enhances tyrosine phosphorylation and DNA synthesis through phospholipase C-coupled receptor via Ca(2+)-dependent intracellular pathway in NIH-3T3 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 3T3 Cells; Alkaloids; Animals; Calcium; Dinoprost; DNA; Ionomycin; Isoquinolines; Mice; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Receptors, Prostaglandin; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Thymidine; Type C Phospholipases; Tyrosine | 1994 |
Role of the carboxyl-terminal domains of the insulin and insulin-like growth factor I receptors in receptor function.
Topics: 3T3 Cells; Animals; Base Sequence; DNA Primers; Enzyme Activation; Glucose; Humans; Mice; Molecular Sequence Data; Ornithine Decarboxylase; Peptide Fragments; Phosphorylation; Proto-Oncogene Proteins c-fos; Receptor, IGF Type 1; Receptor, Insulin; RNA, Messenger; Thymidine; Tyrosine | 1994 |
Ligand-induced ubiquitination of the platelet-derived growth factor beta-receptor plays a negative regulatory role in its mitogenic signaling.
Topics: Amino Acid Sequence; Animals; Aorta; Base Sequence; Cell Division; Cell Line; DNA; Endothelium, Vascular; Humans; Kinetics; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Platelet-Derived Growth Factor; Receptors, Platelet-Derived Growth Factor; Recombinant Proteins; Swine; Thymidine; Tyrosine; Ubiquitins | 1993 |
Transmembrane signaling by epidermal growth factor receptors lacking autophosphorylation sites.
Topics: 3T3 Cells; Animals; Cell Adhesion; Cell Division; DNA Replication; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Humans; Kinetics; Mice; Mutagenesis, Site-Directed; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Phosphorylation; Phosphotransferases; Recombinant Proteins; Signal Transduction; Thymidine; Transfection; Tyrosine | 1993 |
fgr proto-oncogene is expressed during terminal granulocytic differentiation of human promyelocytic HL60 cells.
Topics: Cell Transformation, Neoplastic; Dimethyl Sulfoxide; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Granulocytes; Humans; Leukemia, Promyelocytic, Acute; Phosphorylation; Precipitin Tests; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogenes; src-Family Kinases; Thymidine; Tritium; Tumor Cells, Cultured; Tyrosine | 1993 |
Differing signal transductions elicited by three isoforms of platelet-derived growth factor in vascular smooth muscle cells.
Topics: Animals; Blotting, Western; Calcium; Cells, Cultured; Inositol 1,4,5-Trisphosphate; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Rats; Rats, Inbred WKY; Signal Transduction; Thymidine; Type C Phospholipases; Tyrosine | 1993 |
Hypoxia induces vascular endothelial growth factor in cultured human endothelial cells.
Topics: Cell Hypoxia; Cells, Cultured; Cobalt; Culture Media, Conditioned; Endothelial Growth Factors; Endothelium, Vascular; Fibroblasts; Humans; Lymphokines; Nickel; Phosphorylation; RNA, Messenger; Tetradecanoylphorbol Acetate; Thymidine; Tritium; Tyrosine; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1995 |
Tumorigenic and mitogenic capacities are reduced in transfected fibroblasts expressing mutant insulin-like growth factor (IGF)-I receptors. The role of tyrosine residues 1250, 1251, and 1316 in the carboxy-terminus of the IGF-I receptor.
Topics: 3T3 Cells; Animals; Base Sequence; Fibroblasts; Humans; Insulin-Like Growth Factor I; Mice; Mice, Nude; Mitosis; Molecular Sequence Data; Mutation; Neoplasms, Experimental; Peptide Fragments; Phosphorylation; Protein-Tyrosine Kinases; Receptors, Somatomedin; Thymidine; Transfection; Tyrosine | 1996 |
A comparison of epidermal growth factor receptor-mediated mitogenic signaling in response to transforming growth factor alpha and epidermal growth factor in cultured fetal rat hepatocytes.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Densitometry; DNA; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Female; Immunoblotting; Liver; Mitogens; Phosphorylation; Pregnancy; Proteins; Rats; Rats, Sprague-Dawley; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; src Homology Domains; Thymidine; Time Factors; Transforming Growth Factor alpha; Tyrosine | 1996 |
Divergent selection for high or low growth rate modifies the response of muscle cells to serum or insulin-like growth factor-I in vitro.
Topics: Aging; Analysis of Variance; Animals; Biological Transport; Body Weight; Cell Division; Cells, Cultured; Chickens; DNA; Humans; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Male; Muscle, Skeletal; Protein Biosynthesis; Recombinant Proteins; Thymidine; Tyrosine | 1996 |
Tyrosine phosphorylation is crucial for growth signaling by tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2).
Topics: Benzoquinones; Calcium-Calmodulin-Dependent Protein Kinases; DNA; Enzyme Activation; Genistein; Glycoproteins; Humans; Hydroquinones; Isoflavones; Lactams, Macrocyclic; Mitogen-Activated Protein Kinase 1; Osteosarcoma; Phosphorylation; Protease Inhibitors; Protein-Tyrosine Kinases; Proteins; Quinones; Rifabutin; Signal Transduction; Thymidine; Time Factors; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinases; Tritium; Tumor Cells, Cultured; Tyrosine | 1996 |
Stimulation of the mitogen-activated protein kinase via the A2A-adenosine receptor in primary human endothelial cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Antibodies, Monoclonal; Calcium-Calmodulin-Dependent Protein Kinases; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Fibroblast Growth Factor 2; Flavonoids; GTP-Binding Proteins; Humans; Isoproterenol; Phosphorylation; Receptors, Purinergic P1; Thymidine; Tyrosine; Vasodilator Agents | 1997 |
Fluoride at mitogenic doses induces a sustained activation of p44mapk, but not p42mapk, in human TE85 osteosarcoma cells.
Topics: Bone and Bones; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Dose-Response Relationship, Drug; Enzyme Activation; Fibroblasts; Fluorides; Homeostasis; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitogens; Phosphorylation; Protein-Tyrosine Kinases; Skin; Thymidine; Tumor Cells, Cultured; Tyrosine; Vanadates | 1997 |
Inhibition of platelet-derived growth factor receptor tyrosine kinase by atrial natriuretic peptide.
Topics: Animals; Aorta; Atrial Natriuretic Factor; Cells, Cultured; Cyclic GMP; Humans; Muscle, Smooth, Vascular; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Thymidine; Tritium; Tyrosine | 1997 |
TGF-beta isoforms differentially attenuate EGF mitogenicity and receptor activity in fetal lung mesenchymal cells.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Epidermal Growth Factor; ErbB Receptors; Fetus; Isomerism; Lung; Mesoderm; Mice; Mitogens; Phosphorylation; Phosphotransferases; Signal Transduction; Substrate Specificity; Thymidine; Transforming Growth Factor beta; Tyrosine | 1997 |
Regulation of interleukin 4-mediated signaling by naturally occurring dominant negative and attenuated forms of human Stat6.
Topics: Amino Acid Sequence; Cell Line; Dimerization; DNA; DNA, Complementary; Humans; Interleukin-4; Molecular Sequence Data; Phosphorylation; RNA, Messenger; Signal Transduction; Spectrometry, Fluorescence; STAT6 Transcription Factor; Thymidine; Trans-Activators; Transcriptional Activation; Tyrosine | 1998 |
PDGF alpha-receptor mediated cellular responses are not dependent on Src family kinases in endothelial cells.
Topics: Actins; Amino Acid Sequence; Cell Line; Endothelium, Vascular; Molecular Sequence Data; Mutation; Phosphorylation; Receptors, Platelet-Derived Growth Factor; src-Family Kinases; Thymidine; Tritium; Tyrosine | 1998 |
UV resonance Raman spectroscopy of DNA and protein constituents of viruses: assignments and cross sections for excitations at 257, 244, 238, and 229 nm.
Topics: Deoxyadenosines; Deoxycytidine; Deoxyguanosine; DNA Viruses; DNA, Viral; Phenylalanine; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Sulfates; Thymidine; Tryptophan; Tyrosine; Viral Proteins | 1998 |
Importance of glucose-6-phosphate dehydrogenase activity for cell growth.
Topics: 3T3 Cells; Animals; Cell Division; COS Cells; Dehydroepiandrosterone; Enzyme Inhibitors; Glucosephosphate Dehydrogenase; Mice; NADP; Oxidation-Reduction; Phosphorylation; Ribosemonophosphates; Thymidine; Tyrosine | 1998 |
Density functional studies on herpes simplex virus type 1 thymidine kinase-substrate interactions: the role of Tyr-172 and Met-128 in thymine fixation.
Topics: Adenosine Triphosphate; Binding Sites; Computer Simulation; Hydrogen Bonding; Methionine; Models, Molecular; Simplexvirus; Static Electricity; Thymidine; Thymidine Kinase; Tyrosine; Viral Proteins | 1998 |
Site-specific ribonuclease activity of eukaryotic DNA topoisomerase I.
Topics: Base Sequence; DNA; DNA Topoisomerases, Type I; Eukaryotic Cells; Humans; Kinetics; Molecular Sequence Data; Phosphates; Ribonucleases; RNA, Messenger; Substrate Specificity; Thymidine; Tyrosine; Uridine; Vaccinia virus | 1997 |
Mutation of a Shc binding site tyrosine residue in ErbB3/HER3 blocks heregulin-dependent activation of mitogen-activated protein kinase.
Topics: 3T3 Cells; Androstadienes; Animals; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; DNA Primers; DNA Replication; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Glycoproteins; Mice; Mutagenesis, Site-Directed; Neuregulin-1; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins; Rats; Receptor, ErbB-3; Signal Transduction; Thymidine; Transfection; Tritium; Tyrosine; Wortmannin | 1998 |
Local inhibition of tyrosine kinase activity markedly attenuates the development of intimal hyperplasia in experimental vein grafts.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Bradykinin; Dimethyl Sulfoxide; DNA; Enzyme Inhibitors; Hyperplasia; Jugular Veins; Microscopy, Electron, Scanning; Nitriles; Norepinephrine; Phosphorylation; Potassium Chloride; Protein-Tyrosine Kinases; Rabbits; Serotonin; Thymidine; Tritium; Tunica Intima; Tyrosine; Vasoconstrictor Agents | 1998 |
Superoxide scavenging effect of Ginkgo biloba extract on serotonin-induced mitogenesis.
Topics: Animals; Cattle; Cell Division; Cricetinae; Flavonoids; Free Radical Scavengers; Ginkgo biloba; Muscle, Smooth, Vascular; Phosphorylation; Plant Extracts; Serotonin; Serotonin Antagonists; Superoxides; Thymidine; Tyrosine | 1998 |
The low-molecular-weight phosphotyrosine protein phosphatase, when overexpressed, reduces the mitogenic response to macrophage colony-stimulating factor and tyrosine phosphorylation of its receptor.
Topics: 3T3 Cells; Animals; Cell Count; Cell Line; DNA; Humans; Macrophage Colony-Stimulating Factor; Macrophages; Mice; Mitogens; Molecular Weight; Phosphorylation; Protein Tyrosine Phosphatases; Receptor, Macrophage Colony-Stimulating Factor; Signal Transduction; Thymidine; Transfection; Tritium; Tyrosine | 1998 |
Mutation of C-terminal tyrosine residues Y497/Y504 of the Src-family member Bsk/Iyk decreases NIH3T3 cell proliferation.
Topics: 3T3 Cells; Animals; Cell Cycle; Cell Division; Gene Expression; Mice; Mutagenesis, Site-Directed; Neoplasm Proteins; Protein-Tyrosine Kinases; src-Family Kinases; Subcellular Fractions; Thymidine; Tyrosine | 1998 |
Properties of uracil transport by vegetative mycelium of Trichoderma viride.
Topics: Biological Transport; Carrier Proteins; Cytosine; Fungal Proteins; Histidine; Ionophores; Lysine; Methanol; Monensin; Solvents; Thymidine; Trichoderma; Tritium; Tyrosine; Uracil; Valinomycin | 1999 |
Site-directed mutagenesis of phosphate-contacting amino acids of bovine pancreatic deoxyribonuclease I.
Topics: Amino Acids; Animals; Arginine; Asparagine; Cattle; Deoxyribonuclease I; DNA; Hydrolysis; Mutagenesis, Site-Directed; RNA, Transfer, Tyr; Serine; Substrate Specificity; Sugar Phosphates; Threonine; Thymidine; Tyrosine | 1999 |
Role of the Src homology 2 (SH2) domain and C-terminus tyrosine phosphorylation sites of SH2-containing inositol phosphatase (SHIP) in the regulation of insulin-induced mitogenesis.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Bromodeoxyuridine; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Fibroblasts; GRB2 Adaptor Protein; Humans; Insulin; Mitosis; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Proteins; Rats; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; src Homology Domains; Thymidine; Transfection; Tyrosine | 1999 |
Adrenomedullin decreases extracellular signal-regulated kinase activity through an increase in protein phosphatase-2A activity in mesangial cells.
Topics: Adrenomedullin; Animals; Apoptosis; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Glomerular Mesangium; Mitogen-Activated Protein Kinases; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Peptides; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Rats; Rats, Sprague-Dawley; Thymidine; Tyrosine | 2000 |
Kinetics and crystal structure of the wild-type and the engineered Y101F mutant of Herpes simplex virus type 1 thymidine kinase interacting with (North)-methanocarba-thymidine.
Topics: Amino Acid Substitution; Binding, Competitive; Bridged Bicyclo Compounds; Crystallization; Crystallography, X-Ray; Enzyme Inhibitors; Herpesvirus 1, Human; Humans; Kinetics; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Phosphorylation; Protein Conformation; Thymidine; Thymidine Kinase; Tyrosine | 2000 |
Expression of thrombopoietin receptor and its functional role in human B-precursor leukemia cells with 11q23 translocation or Philadelphia chromosome.
Topics: Antigens, Surface; Chromosome Mapping; Chromosomes, Human, Pair 11; DNA; Gene Expression; Humans; Leukemia, Lymphoid; Neoplasm Proteins; Philadelphia Chromosome; Phosphorylation; Proto-Oncogene Proteins; Receptors, Cytokine; Receptors, Thrombopoietin; RNA, Messenger; Thrombopoietin; Thymidine; Translocation, Genetic; Tritium; Tumor Cells, Cultured; Tumor Stem Cell Assay; Tyrosine | 2000 |
Synthesis and use of DNA containing a 5'-bridging phosphorothioate as a suicide substrate for type I DNA topoisomerases.
Topics: Binding Sites; DNA; DNA Topoisomerases, Type I; Kinetics; Oligodeoxyribonucleotides; Phosphates; Substrate Specificity; Thymidine; Topoisomerase I Inhibitors; Tyrosine; Vaccinia virus | 2001 |
Polyclonal anticardiolipin antibodies purified from sera of patients with active systemic lupus erythematosus induce apoptosis of the cultured glomerular mesangial cells.
Topics: Animals; Antibodies, Anticardiolipin; Apoptosis; Cells, Cultured; Gene Expression; Glomerular Mesangium; Lupus Erythematosus, Systemic; Phosphorylation; Rats; Rats, Sprague-Dawley; Thymidine; Tyrosine | 2000 |
Dopamine induces ERK activation in renal epithelial cells through H2O2 produced by monoamine oxidase.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Cell Division; Cells, Cultured; Dopamine; Enzyme Activation; Hydrogen Peroxide; Kidney Tubules, Proximal; Mitogen-Activated Protein Kinases; Monoamine Oxidase; Phosphorylation; Proteins; Rats; Rats, Sprague-Dawley; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Substrate Specificity; Thymidine; Tyramine; Tyrosine | 2001 |
Site-directed mutagenesis of human immunodeficiency virus type 1 reverse transcriptase at amino acid position 138.
Topics: Alanine; Anti-HIV Agents; Aspartic Acid; Cell Line; Deoxyguanine Nucleotides; Dideoxynucleotides; DNA-Directed DNA Polymerase; Glutamic Acid; Glutamine; HIV Reverse Transcriptase; HIV-1; Humans; Lysine; Mutagenesis, Site-Directed; Nucleosides; Phenylalanine; Recombination, Genetic; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Spiro Compounds; Thymidine; Tyrosine; Uridine | 2001 |
Angiotensin II-induced stimulation of p21-activated kinase and c-Jun NH2-terminal kinase is mediated by Rac1 and Nck.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Cells, Cultured; CHO Cells; Cricetinae; Enzyme Activation; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Oncogene Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Protein Transport; rac1 GTP-Binding Protein; Rats; Rats, Inbred WKY; Thymidine; Tyrosine | 2001 |
Tyrosine-phosphorylated SOCS-3 inhibits STAT activation but binds to p120 RasGAP and activates Ras.
Topics: 3T3 Cells; Amino Acid Motifs; Animals; Blotting, Western; Cell Division; Cell Line; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Epidermal Growth Factor; Erythropoietin; Humans; Interleukin-2; Mice; Milk Proteins; Mitogen-Activated Protein Kinases; Mutation; p120 GTPase Activating Protein; Phosphorylation; Platelet-Derived Growth Factor; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Proteins; ras Proteins; Repressor Proteins; Signal Transduction; src Homology Domains; STAT5 Transcription Factor; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Thymidine; Trans-Activators; Transcription Factors; Transfection; Tyrosine | 2001 |
Angiotensin IV induces tyrosine phosphorylation of focal adhesion kinase and paxillin in proximal tubule cells.
Topics: Angiotensin II; Animals; Binding, Competitive; Calcium; Cyclic AMP; Cyclic GMP; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Focal Adhesion Protein-Tyrosine Kinases; Iodine Radioisotopes; Kidney Tubules, Proximal; LLC-PK1 Cells; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Renin-Angiotensin System; Signal Transduction; Swine; Thymidine; Tritium; Tyrosine | 2001 |
Src homology 2 domain-containing inositol 5-phosphatase 1 mediates cell cycle arrest by FcgammaRIIB.
Topics: Animals; Antigens, CD; Blotting, Western; Bone Marrow Cells; Catalytic Domain; Cell Cycle; Cell Division; Cell Survival; Dimerization; DNA, Complementary; Dose-Response Relationship, Drug; Gene Deletion; Gene Transfer Techniques; MAP Kinase Signaling System; Mice; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins c-kit; Rats; Receptors, IgG; Retroviridae; Signal Transduction; src Homology Domains; Stem Cell Factor; Thymidine; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine | 2001 |
IRS-1 tyrosine phosphorylation reflects insulin-induced metabolic and mitogenic responses in 3T3-L1 pre-adipocytes.
Topics: 3T3 Cells; Adipocytes; Animals; Blotting, Western; DNA; Dose-Response Relationship, Drug; Epidermal Growth Factor; Glycogen; Insulin; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Recombinant Fusion Proteins; Thymidine; Time Factors; Tyrosine | 2001 |
Differential effects of bacterial toxins on mitogenic actions of sodium fluoride and those of aluminum fluoride in human TE85 osteosarcoma cells.
Topics: Alkaline Phosphatase; Aluminum Compounds; Bone Neoplasms; Cell Division; Cholera Toxin; Fluorides; Humans; Mitogen-Activated Protein Kinases; Mitogens; Osteosarcoma; Pertussis Toxin; Phosphorylation; Signal Transduction; Sodium Fluoride; Thymidine; Tumor Cells, Cultured; Tyrosine; Virulence Factors, Bordetella | 2001 |
Evidence that peroxynitrite affects human osteoblast proliferation and differentiation.
Topics: Alkaline Phosphatase; Catalase; Cell Differentiation; Cell Division; Cells, Cultured; Humans; Interferon-gamma; Interleukin-1; Molsidomine; Nitric Oxide Donors; Nitrites; Osteoblasts; Peroxynitrous Acid; Recombinant Proteins; Superoxide Dismutase; Thymidine; Tumor Necrosis Factor-alpha; Tyrosine | 2002 |
The herbal medicine Sairei-to inhibits proliferation of rat mesangial cells.
Topics: Animals; Blood Proteins; Cell Division; Cells, Cultured; Cyclic AMP; Drugs, Chinese Herbal; Glomerular Mesangium; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-raf; Rats; S Phase; Thymidine; Tritium; Tyrosine | 2002 |
Piceatannol in combination with low doses of cyclosporine A prolongs kidney allograft survival in a stringent rat transplantation model.
Topics: Animals; Cyclosporine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Graft Survival; Immunosuppressive Agents; Kidney; Kidney Transplantation; Leukocyte Count; Phosphorylation; Rats; Rats, Inbred ACI; Rats, Inbred Lew; Receptors, Antigen, T-Cell; Reference Values; Stem Cells; Stilbenes; T-Lymphocytes; T-Lymphocytes, Cytotoxic; Thymidine; Transplantation, Homologous; Tyrosine | 2002 |
Sef inhibits fibroblast growth factor signaling by inhibiting FGFR1 tyrosine phosphorylation and subsequent ERK activation.
Topics: 3T3 Cells; Adenoviridae; Animals; Cell Division; Cell Line; Cloning, Molecular; COS Cells; Enzyme Activation; Fibroblast Growth Factors; Gene Expression Regulation, Enzymologic; Genetic Vectors; Humans; Immunoblotting; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Membrane Proteins; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Platelet-Derived Growth Factor; Precipitin Tests; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Serine; Signal Transduction; Threonine; Thymidine; Tyrosine | 2003 |
[Autoradiographic investigation on the incorporation of H3 amino acids into the cell nucleus during the G-1 phase and the S-phase of normal and x-radiated mice].
Topics: Amino Acids; Animals; Cell Nucleus; DNA; Mice; Radiation Effects; Thymidine; Tyrosine | 1963 |
THE EFFECT OF SPERMINE ON THE ACCUMULATION OF NUCLEIC ACIDS AND PROTEIN IN MAMMALIAN CELLS.
Topics: Carbon Isotopes; Carcinoma; Carcinoma 256, Walker; DNA; DNA, Neoplasm; Metabolism; Neoplasm Proteins; Nucleic Acids; Nucleosides; Pharmacology; Proteins; Radiometry; Research; RNA; RNA, Neoplasm; Spermine; Thymidine; Tissue Culture Techniques; Tyrosine; Uridine | 1965 |
Mechanisms involved in the stimulatory effect of advanced glycation end products on growth of rat aortic smooth muscle cells.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Blood Glucose; Blotting, Western; Cell Count; Cell Division; CHO Cells; Cricetinae; Electrophoretic Mobility Shift Assay; Galectin 3; Glycation End Products, Advanced; Muscle, Smooth, Vascular; NF-kappa B; Phosphorylation; Rats; Rats, Inbred WKY; Receptor, Platelet-Derived Growth Factor beta; Reverse Transcriptase Polymerase Chain Reaction; Serum Albumin, Bovine; Stimulation, Chemical; Thymidine; Tyrosine | 2003 |
PDGF stimulates DNA synthesis in human vascular smooth muscle cells via a novel wortmannin-insensitive phosphatidylinositol 3-kinase.
Topics: Androstadienes; Animals; Cattle; DNA; Enzyme Inhibitors; Humans; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet-Derived Growth Factor; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serum; Thymidine; Tritium; Tyrosine; Wortmannin | 2003 |
Effect of inhibiting vacuolar acidification on insulin signaling in hepatocytes.
Topics: Animals; Antioxidants; Binding Sites; Cell Division; Cell Membrane; Cells, Cultured; Chloroquine; Endosomes; Enzyme Inhibitors; Evolution, Molecular; Glycogen; Hepatocytes; Histidine; Insulin; Macrolides; Male; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Mutation; Phosphatidylinositol 3-Kinases; Phosphorylation; Phylogeny; Rats; Rats, Sprague-Dawley; Serine; Signal Transduction; Superoxides; Swine; Thymidine; Time Factors; Tyrosine | 2004 |
Molecular determinants of multi-nucleoside analogue resistance in HIV-1 reverse transcriptases containing a dipeptide insertion in the fingers subdomain: effect of mutations D67N and T215Y on removal of thymidine nucleotide analogues from blocked DNA prim
Topics: Adenosine Triphosphate; Amino Acid Sequence; Base Sequence; Codon; DNA; DNA Primers; Drug Resistance, Viral; Gene Deletion; HIV Reverse Transcriptase; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Peptides; Phenotype; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Reverse Transcriptase Inhibitors; Sequence Homology, Amino Acid; Stavudine; Thymidine; Time Factors; Tyrosine; Zidovudine | 2004 |
Activation of Ras-Ral pathway attenuates p53-independent DNA damage G2 checkpoint.
Topics: Blotting, Western; CDC2 Protein Kinase; Cell Line, Tumor; Cell Separation; Cyclin B; Cyclin B1; DNA; DNA Damage; Doxorubicin; Ethyl Methanesulfonate; Fibroblasts; Flow Cytometry; G1 Phase; G2 Phase; Genes, Dominant; Humans; Microscopy, Fluorescence; Mitosis; Mutation; Osteosarcoma; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; ral Guanine Nucleotide Exchange Factor; ras Proteins; Retroviridae; Signal Transduction; Thymidine; Time Factors; Tumor Suppressor Protein p53; Tyrosine | 2004 |
ALK receptor tyrosine kinase promotes cell growth and neurite outgrowth.
Topics: Adaptor Proteins, Signal Transducing; Anaplastic Lymphoma Kinase; Animals; Antibodies, Monoclonal; Cell Line; Cell Line, Tumor; Cell Proliferation; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Flavonoids; Humans; Immunoblotting; Immunoprecipitation; Insulin Receptor Substrate Proteins; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogens; Neuroblastoma; Neurons; NIH 3T3 Cells; Phosphoproteins; Phosphorylation; Plasmids; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Receptor Protein-Tyrosine Kinases; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Thymidine; Time Factors; Tyrosine; Ubiquitin-Protein Ligases | 2004 |
Insulin inhibits platelet-derived growth factor-induced cell proliferation.
Topics: Animals; Anti-Infective Agents, Local; Cell Communication; Cell Line; Cell Proliferation; Culture Media, Serum-Free; Down-Regulation; Endocytosis; Gentian Violet; Hydrogen Peroxide; Immunoprecipitation; Insulin; Mice; Mitosis; NIH 3T3 Cells; Oxidation-Reduction; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet-Derived Growth Factor; Reactive Oxygen Species; Receptor, Insulin; Receptors, Platelet-Derived Growth Factor; src-Family Kinases; Thymidine; Time Factors; Tyrosine | 2005 |
Phorbol 12-myristate 13-acetate induces epidermal growth factor receptor transactivation via protein kinase Cdelta/c-Src pathways in glioblastoma cells.
Topics: Acetophenones; Astrocytes; Benzopyrans; Blotting, Western; Butadienes; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; ErbB Receptors; Glioblastoma; Humans; Immunoprecipitation; Models, Biological; Nitriles; Phosphorylation; Protein Isoforms; Protein Kinase C; Protein Kinase C-delta; RNA, Small Interfering; src-Family Kinases; Tetradecanoylphorbol Acetate; Thymidine; Time Factors; Transcriptional Activation; Tyrosine | 2005 |
Expression and function of receptors for insulin-like growth factor-I and insulin in human coronary artery smooth muscle cells.
Topics: Blotting, Western; Cells, Cultured; Coronary Vessels; DNA, Complementary; Glucose; Humans; Immunoprecipitation; Myocytes, Smooth Muscle; Phosphorylation; Receptor, IGF Type 1; Receptor, Insulin; Reverse Transcriptase Polymerase Chain Reaction; RNA; Thymidine; Tyrosine | 2005 |
A single amino acid substitution in the activation loop defines the decoy characteristic of VEGFR-1/FLT-1.
Topics: Amino Acid Sequence; Animals; Asparagine; Aspartic Acid; Blotting, Western; Cell Membrane; Cell Proliferation; Cell Transformation, Neoplastic; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Enzyme Activation; Fibroblasts; Humans; Immunoprecipitation; Ligands; Mice; Molecular Sequence Data; Mutation; Neovascularization, Pathologic; NIH 3T3 Cells; Phosphorylation; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Receptor Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Thymidine; Time Factors; Tyrosine; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2006 |
Changes in tumor metabolism as readout for Mammalian target of rapamycin kinase inhibition by rapamycin in glioblastoma.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Proliferation; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Glioblastoma; Glucose; Humans; Mice; Positron-Emission Tomography; Protein Kinases; Sirolimus; Thymidine; Thymidine Kinase; TOR Serine-Threonine Kinases; Tyrosine | 2008 |
N(3)-Substituted thymidine analogues V: synthesis and preliminary PET imaging of N(3)-[(18)F]fluoroethyl thymidine and N(3)-[(18)F]fluoropropyl thymidine.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Humans; Metabolic Clearance Rate; Mice; Mice, Nude; Organ Specificity; Pilot Projects; Positron-Emission Tomography; Radiopharmaceuticals; Thymidine; Tissue Distribution; Tyrosine | 2008 |
(-)-Epigallocatechin-3-Gallate protects SH-SY5Y cells against 6-OHDA-induced cell death through STAT3 activation.
Topics: Adrenergic Agents; Analysis of Variance; Catechin; Cell Death; Cell Differentiation; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Interactions; Humans; Neuroblastoma; Neuroprotective Agents; Oxidopamine; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles; Thymidine; Time Factors; Tritium; Tyrosine | 2009 |
Type II cGMP-dependent protein kinase inhibits EGF-triggered signal transduction of the MAPK/ERK-mediated pathway in gastric cancer cells.
Topics: Cell Line, Tumor; Cell Nucleus; Cyclic GMP-Dependent Protein Kinases; Epidermal Growth Factor; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; GRB2 Adaptor Protein; Humans; MAP Kinase Signaling System; Oncogene Protein p21(ras); Phosphorylation; Protein Binding; Protein Transport; Proto-Oncogene Proteins c-raf; SOS1 Protein; Stomach Neoplasms; Thymidine; Tyrosine | 2012 |
The radical SAM enzyme spore photoproduct lyase employs a tyrosyl radical for DNA repair.
Topics: Cysteine; DNA Repair; Geobacillus; Models, Chemical; Proteins; Spores, Bacterial; Thymidine; Tyrosine | 2013 |
Aurora-A recruitment and centrosomal maturation are regulated by a Golgi-activated pool of Src during G2.
Topics: Animals; Aurora Kinase A; Centrosome; Chromosome Segregation; CSK Tyrosine-Protein Kinase; G2 Phase; Golgi Apparatus; HeLa Cells; Humans; Indoles; Phosphorylation; Rats; RNA Interference; RNA, Small Interfering; S Phase; src-Family Kinases; Sulfonamides; Thymidine; Tyrosine | 2016 |
Oxidative cross-linking of proteins to DNA following ischemia-reperfusion injury.
Topics: Animals; DNA Adducts; Free Radicals; Male; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Stress; Proteomics; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Thymidine; Tyrosine | 2018 |
Tyr51: Key Determinant of the Low Thermostability of the Colwellia psychrerythraea Cold-Shock Protein.
Topics: Alteromonadaceae; Amino Acid Sequence; Bacterial Proteins; Cold Shock Proteins and Peptides; Hot Temperature; Hydrophobic and Hydrophilic Interactions; Molecular Docking Simulation; Molecular Dynamics Simulation; Protein Binding; Protein Conformation; Protein Folding; Protein Stability; Sequence Alignment; Thymidine; Tyrosine | 2018 |