Page last updated: 2024-08-17

thymidine and trimetrexate

thymidine has been researched along with trimetrexate in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19904 (44.44)18.7374
1990's3 (33.33)18.2507
2000's2 (22.22)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bertino, JR; Sobrero, AF1
Branda, RF; Carney, JK; McCormack, JJ; Moore, AL; Perlmutter, CA1
Galivan, J; Nimec, Z; Rhee, M1
Besserer, JA; Boritzki, TJ; Elslager, EF; Fry, DW; Jackson, RC; Leopold, WR; Sloan, BJ1
Allay, JA; Belt, JA; Blakley, RL; Sorrentino, BP; Spencer, HT; Wilkinson, SL1
Blakley, RL; Lewis, WS; Mareya, SM; Patel, M; Sleep, SE; Sorrentino, BP; Spencer, HT1
Ando, Y; Hirahara, I; Kobayashi, H; Ma, L; Miyachi, H; Sonehara, H; Takemura, Y1
Faessel, HM; Greco, WR; Rustum, YM; Slocum, HK1
Banerjee, D; Bertino, JR; Li, WW; Magro, PG; Russo, AJ1

Other Studies

9 other study(ies) available for thymidine and trimetrexate

ArticleYear
Endogenous thymidine and hypoxanthine are a source of error in evaluating methotrexate cytotoxicity by clonogenic assays using undialyzed fetal bovine serum.
    International journal of cell cloning, 1986, Volume: 4, Issue:1

    Topics: Adenocarcinoma; Animals; Cattle; Cell Adhesion; Colonic Neoplasms; Colony-Forming Units Assay; Culture Media; Dose-Response Relationship, Drug; Humans; Hypoxanthines; Leucovorin; Methotrexate; Neoplastic Stem Cells; Quinazolines; Thymidine; Trimetrexate

1986
Inhibition of lymphocyte nucleic acid metabolism and antibody production by trimetrexate.
    Biochemical pharmacology, 1987, May-15, Volume: 36, Issue:10

    Topics: Antibody Formation; Deoxyuridine; DNA; Humans; Interphase; Lymphocytes; Methotrexate; Nucleic Acids; Quinazolines; Thymidine; Trimetrexate

1987
Synergistic growth inhibition of rat hepatoma cells exposed in vitro to N10-propargyl-5,8-dideazafolate with methotrexate or the lipophilic antifolates trimetrexate or metoprine.
    Cancer research, 1987, Oct-15, Volume: 47, Issue:20

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Deoxyuridine; Folic Acid; Folic Acid Antagonists; Liver Neoplasms, Experimental; Methotrexate; Pyrimethamine; Quinazolines; Rats; Thymidine; Thymidylate Synthase; Trimetrexate

1987
Biochemical pharmacology of the lipophilic antifolate, trimetrexate.
    Advances in enzyme regulation, 1984, Volume: 22

    Topics: Animals; Cell Line; Culture Techniques; Deoxyuridine; Drug Resistance; Folic Acid; Folic Acid Antagonists; Humans; Kinetics; Leucovorin; Leukemia L1210; Lymphocytes; Methotrexate; Mice; Mice, Inbred Strains; Quinazolines; Ribonucleotides; Thymidine; Trimetrexate

1984
Sensitization of hematopoietic stem and progenitor cells to trimetrexate using nucleoside transport inhibitors.
    Blood, 1997, Nov-01, Volume: 90, Issue:9

    Topics: Animals; Antimetabolites, Antineoplastic; Biological Transport; Cell Death; Drug Resistance, Neoplasm; Female; Hematopoietic Stem Cells; Humans; Mice; Mice, Inbred C57BL; Thioinosine; Thionucleotides; Thymidine; Trimetrexate

1997
Comparison of the protection of cells from antifolates by transduced human dihydrofolate reductase mutants.
    Human gene therapy, 1997, Nov-20, Volume: 8, Issue:17

    Topics: Aminopterin; Animals; Cell Survival; Drug Resistance, Neoplasm; Folic Acid Antagonists; Gene Expression; Genetic Variation; Growth Inhibitors; Humans; Kinetics; Methotrexate; Pyrimidines; Rabbits; Tetrahydrofolate Dehydrogenase; Thymidine; Transfection; Trimetrexate

1997
Microsatellite instability and clonal heterogeneity of MDR1 messenger RNA expression in trimetrexate-resistant human leukemia MOLT-3 cells developed in thymidine.
    International journal of cancer, 1999, Jul-02, Volume: 82, Issue:1

    Topics: Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Resistance, Neoplasm; Humans; Leukemia; Microsatellite Repeats; RNA, Messenger; Tetrahydrofolate Dehydrogenase; Thymidine; Trimetrexate; Tumor Cells, Cultured

1999
Thymidine and hypoxanthine protection patterns of the folic acid-enhanced synergies for combinations of trimetrexate plus a polyglutamylatable inhibitor of purine or thymidylate synthesis against human ileocecal HCT-8 cells.
    International journal of oncology, 2003, Volume: 23, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cecal Neoplasms; Cell Division; Drug Resistance, Multiple; Drug Synergism; Enzyme Inhibitors; Folic Acid; Glutamates; Hematinics; Humans; Hydroxymethyl and Formyl Transferases; Hypoxanthine; Ileal Neoplasms; Peptide Synthases; Phosphoribosylglycinamide Formyltransferase; Pyrimidines; Quinazolines; Thiophenes; Thymidine; Thymidylate Synthase; Trimetrexate; Tumor Cells, Cultured

2003
p14ARF expression increases dihydrofolate reductase degradation and paradoxically results in resistance to folate antagonists in cells with nonfunctional p53.
    Cancer research, 2004, Jun-15, Volume: 64, Issue:12

    Topics: Cell Division; Cell Line, Tumor; Drug Resistance, Neoplasm; Enzyme Stability; Fibrosarcoma; Folic Acid Antagonists; Humans; Methotrexate; Neoplastic Stem Cells; Quinazolines; Tetrahydrofolate Dehydrogenase; Thiophenes; Thymidine; Thymidylate Synthase; Trimetrexate; Tumor Suppressor Protein p14ARF; Tumor Suppressor Protein p53

2004