Page last updated: 2024-08-17

thymidine and thymidine glycol

thymidine has been researched along with thymidine glycol in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199012 (29.27)18.7374
1990's9 (21.95)18.2507
2000's11 (26.83)29.6817
2010's7 (17.07)24.3611
2020's2 (4.88)2.80

Authors

AuthorsStudies
Boorstein, RJ; Cadet, J; Lustig, MJ; Teebor, GW1
Holwitt, E; Kan, LS; Lee, HC; Swenberg, C; Vaishnav, Y1
Box, HC; Kelman, DJ; Sharma, M1
Frenkel, K1
Bergtold, DS; Simic, MG1
Hegi, ME; Lutz, WK; Sagelsdorff, P1
Adelman, R; Ames, BN; Saul, RL1
Alessio, H; Bergtold, DS; Cutler, RG; Simic, MG1
Cadet, J; Cummings, A; Frenkel, K; Shaw, A; Teebor, G; Voituriez, L1
Chrzan, K; Frenkel, K; Steinberg, JJ; Teebor, GW; Troll, W1
Achey, PM; Wright, CF1
Ames, BN; Cathcart, R; Saul, RL; Schwiers, E1
Balland, A; Berger, M; Cadet, J1
Duker, NJ; Frenkel, K; Goldstein, MS; Teebor, GW1
Frenkel, K; Goldstein, MS; Teebor, GW1
Cao, EH; Wang, JJ1
Buchko, GW; Soderlind, KJ; Weinfeld, M1
Frenkel, K; Wei, H; Wei, L1
Markey, SP; Naritsin, DB1
Greferath, R; Nehls, P1
Blaszkewicz, M; Bolt, HM; Brüning, T; Kocher, K; Makropoulos, V; Sundberg, A; Thier, R1
Heintz, B; Kocher, K; Makropoulos, W; Mertens, PR; Schwarz, ER; Stefanidis, I1
Le, XC; Leadon, SA; Lee, J; Weinfeld, M; Xing, JZ1
Wang, Y; Zhang, Q1
Wang, Y1
Ito, T; Kondo, A; Nishimoto, S; Terada, S1
Bransfield, LA; Croteau, DL; Greenberg, MM; Imoto, S; Van Houten, B1
Burenina, O; Dolinnaya, N; Ellis, JS; Fedotova, E; Gajdos, V; Hianik, T; Kubareva, E; Oretskaya, T; Romanova, E; Thompson, M; Yang, F1
Jiang, Y; Wang, Y1
Greenberg, MM; Huang, H; Imoto, S1
Gregg, EO; Lowe, FJ; McEwan, M1
Cao, H; Jiang, Y; Wang, Y1
Dolinnaya, NG; Kubareva, EA; Oretskaya, TS; Romanova, EA; Trikin, RM1
Gregg, EO; Lowe, FJ; Luettich, K1
Friedhoff, P; Heinze, RJ; Kubareva, EA; Oretskaya, TS; Perevozchikova, SA; Romanova, EA; Trikin, RM1
Kitabatake, A; Koide, Y; Suzuki, T1
Greenberg, MM; Laverty, DJ1
Birnbaum, ER; Brugh, M; Copping, R; Fassbender, ME; John, KD; Kozimor, SA; Mastren, T; Nortier, FM; Owens, A; Parker, TG; Radchenko, V; Stein, BW; Wyant, LE1
Greenberg, MM; Yang, K1
Angelini, F; Bruno, C; Guidi, F; Lanza, P; Mancini, A; Meucci, E; Mordente, A; Silvestrini, A; Vergani, E1
Tang, F; Wang, Y; Yuan, BF; Yuan, J1

Reviews

3 review(s) available for thymidine and thymidine glycol

ArticleYear
Oxidation of DNA bases by tumor promoter-activated processes.
    Environmental health perspectives, 1989, Volume: 81

    Topics: Animals; Carcinogens; DNA; Humans; Hydrogen Peroxide; Neutrophils; Oxidation-Reduction; Plasma; Thymidine

1989
Thymidine glycol: the effect on DNA molecular structure and enzymatic processing.
    Biochimie, 2013, Volume: 95, Issue:2

    Topics: Base Pairing; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Directed DNA Polymerase; Endonucleases; Escherichia coli; Humans; Nucleic Acid Conformation; Oligonucleotides; Protein Biosynthesis; Stereoisomerism; Thymidine; Transcription, Genetic

2013
Lung cancer biomarkers for the assessment of modified risk tobacco products: an oxidative stress perspective.
    Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 2013, Volume: 18, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Ascorbic Acid; Biomarkers; Carotenoids; Dehydroascorbic Acid; Deoxyguanosine; F2-Isoprostanes; Humans; Lung Neoplasms; Oxidative Stress; Risk; Smoking; Thymidine; Tobacco Products; Tobacco Smoke Pollution

2013

Trials

1 trial(s) available for thymidine and thymidine glycol

ArticleYear
Urinary thymidine glycol as a biomarker for oxidative stress after kidney transplantation.
    Renal failure, 2000, Volume: 22, Issue:4

    Topics: Adult; Biomarkers; Chromatography, High Pressure Liquid; Follow-Up Studies; Graft Rejection; Graft Survival; Humans; Kidney Failure, Chronic; Kidney Function Tests; Kidney Transplantation; Male; Middle Aged; Oxidative Stress; Postoperative Period; Probability; Reperfusion Injury; Sensitivity and Specificity; Statistics, Nonparametric; Thymidine

2000

Other Studies

37 other study(ies) available for thymidine and thymidine glycol

ArticleYear
Synthesis of the diastereomers of thymidine glycol, determination of concentrations and rates of interconversion of their cis-trans epimers at equilibrium and demonstration of differential alkali lability within DNA.
    Nucleic acids research, 1992, Sep-25, Volume: 20, Issue:18

    Topics: Carbon Radioisotopes; Chromatography, High Pressure Liquid; DNA; Drug Stability; Kinetics; Stereoisomerism; Thymidine

1992
Synthesis and characterization of stereoisomers of 5,6-dihydro-5,6-dihydroxy-thymidine.
    Journal of biomolecular structure & dynamics, 1991, Volume: 8, Issue:5

    Topics: Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Osmium Tetroxide; Stereoisomerism; Temperature; Thymidine

1991
Fluorescence postlabeling assay of cis-thymidine glycol monophosphate in X-irradiated calf-thymus DNA.
    Chemico-biological interactions, 1990, Volume: 74, Issue:1-2

    Topics: Animals; Base Sequence; Cattle; Chromatography, High Pressure Liquid; Dansyl Compounds; Deoxyribonuclease I; DNA; DNA Damage; Magnetic Resonance Spectroscopy; Nitrous Oxide; Oligodeoxyribonucleotides; Spectrometry, Fluorescence; Thymidine; Thymine Nucleotides; Thymus Gland; X-Rays

1990
Background levels of DNA damage.
    Free radical research communications, 1989, Volume: 6, Issue:2-3

    Topics: Animals; DNA; DNA Damage; Free Radicals; Humans; Mice; Oxidation-Reduction; Reference Values; Thymidine

1989
Detection by 32P-postlabeling of thymidine glycol in gamma-irradiated DNA.
    Carcinogenesis, 1989, Volume: 10, Issue:1

    Topics: Cations, Divalent; Chromatography, Affinity; Chromatography, Thin Layer; DNA; DNA Damage; Free Radicals; Gamma Rays; Hydrogen-Ion Concentration; In Vitro Techniques; Mutagens; Oxygen; Phosphorus Radioisotopes; Phosphorylation; Thymidine

1989
Oxidative damage to DNA: relation to species metabolic rate and life span.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:8

    Topics: Aging; Animals; DNA Damage; Energy Metabolism; Glycols; Haplorhini; Mice; Oxidation-Reduction; Thymidine; Thymine

1988
Urine biomarkers for oxidative DNA damage.
    Basic life sciences, 1988, Volume: 49

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Biomarkers; Deoxyguanosine; DNA Damage; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Mice; Rats; Thymidine; Thymine

1988
Quantitative measurement of the diastereoisomers of cis thymidine glycol in gamma-irradiated DNA.
    Free radical research communications, 1987, Volume: 2, Issue:4-6

    Topics: Acetylation; Carbon Radioisotopes; Chromatography, High Pressure Liquid; DNA; Gamma Rays; Magnetic Resonance Spectroscopy; Mass Spectrometry; Stereoisomerism; Thymidine; Tritium

1987
Radiation-like modification of bases in DNA exposed to tumor promoter-activated polymorphonuclear leukocytes.
    Cancer research, 1986, Volume: 46, Issue:11

    Topics: DNA; DNA Damage; Dose-Response Relationship, Radiation; Free Radicals; Humans; Hydroxides; In Vitro Techniques; Iron; Neutrophils; Stereoisomerism; Tetradecanoylphorbol Acetate; Thymidine; Transferrin

1986
Inducible repair of thymine ring saturation damage in phi X174 DNA.
    Radiation research, 1983, Volume: 93, Issue:3

    Topics: Bacteriophage phi X 174; DNA Ligases; DNA Repair; DNA, Single-Stranded; DNA, Viral; Osmium Tetroxide; Thymidine

1983
Thymine glycol and thymidine glycol in human and rat urine: a possible assay for oxidative DNA damage.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:18

    Topics: Animals; Chromatography, High Pressure Liquid; DNA Replication; Germ-Free Life; Glucose; Humans; Rats; Species Specificity; Spectrophotometry, Ultraviolet; Thymidine; Thymine; Tritium

1984
[Radiation-induced degradation of thymidine in deaerated aqueous solution].
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1981, Volume: 39, Issue:2

    Topics: Cobalt Radioisotopes; Gamma Rays; Solutions; Thymidine; Water

1981
Identification of the cis-thymine glycol moiety in oxidized deoxyribonucleic acid.
    Biochemistry, 1981, Feb-17, Volume: 20, Issue:4

    Topics: Chemical Phenomena; Chemistry; DNA, Bacterial; Escherichia coli; Oxidation-Reduction; Potassium Permanganate; Thymidine; Thymine

1981
Identification of the cis-thymine glycol moiety in chemically oxidized and gamma-irradiated deoxyribonucleic acid by high-pressure liquid chromatography analysis.
    Biochemistry, 1981, Dec-22, Volume: 20, Issue:26

    Topics: Chromatography, High Pressure Liquid; DNA; Gamma Rays; Oxidation-Reduction; Thymidine; Thymine

1981
Oxidative damage to DNA: levels of thymine glycol and thymidine glycol in neoplastic human urines.
    Carcinogenesis, 1993, Volume: 14, Issue:7

    Topics: Adolescent; Adult; Aged; DNA Damage; DNA Repair; Female; Humans; Male; Middle Aged; Neoplasms; Oxidation-Reduction; Thymidine; Thymine

1993
Influence of nucleic acid base aromaticity on substrate reactivity with enzymes acting on single-stranded DNA.
    Nucleic acids research, 1993, Feb-11, Volume: 21, Issue:3

    Topics: Acid Phosphatase; Adenosine Deaminase; Animals; Cattle; Chromatography, High Pressure Liquid; Deoxyribonucleases; DNA, Single-Stranded; Enzymes; Hydrolysis; Kinetics; Phosphoric Diester Hydrolases; Phosphoric Monoester Hydrolases; Phosphorylation; Polynucleotide 5'-Hydroxyl-Kinase; Snakes; Spleen; Stereoisomerism; Substrate Specificity; Thymidine

1993
Sensitivity to tumor promotion of SENCAR and C57BL/6J mice correlates with oxidative events and DNA damage.
    Carcinogenesis, 1993, Volume: 14, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carcinogens; Deoxyguanosine; DNA Damage; Hydrogen Peroxide; Hyperplasia; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Neutrophils; Peroxidase; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thymidine

1993
Assessment of DNA oxidative damage by quantification of thymidine glycol residues using gas chromatography/electron capture negative ionization mass spectrometry.
    Analytical biochemistry, 1996, Oct-01, Volume: 241, Issue:1

    Topics: Animals; Cattle; Chromatography, Gas; DNA; DNA Damage; Mass Spectrometry; Oxidative Stress; Thymidine; Thymus Gland

1996
Monoclonal antibodies to thymidine glycol generated by different immunization techniques.
    Hybridoma, 1997, Volume: 16, Issue:2

    Topics: Animals; Antibody Affinity; Antibody Specificity; Cross Reactions; DNA Damage; Haptens; Hemocyanins; Hybridomas; Immunization; Mice; Mice, Inbred BALB C; Thymidine; Thyroglobulin

1997
Determination of urinary thymidine glycol using affinity chromatography, HPLC and post-column reaction detection: a biomarker of oxidative DNA damage upon kidney transplantation.
    Archives of toxicology, 1999, Volume: 73, Issue:8-9

    Topics: Adult; Biomarkers; Chromatography, Affinity; Chromatography, High Pressure Liquid; DNA Damage; Electrophoresis, Polyacrylamide Gel; Female; Humans; Kidney Glomerulus; Kidney Transplantation; Kidney Tubules; Male; Middle Aged; Proteinuria; Reactive Oxygen Species; Reperfusion Injury; Thymidine

1999
Immunofluorescence detection of radiation-induced DNA base damage.
    Military medicine, 2002, Volume: 167, Issue:2 Suppl

    Topics: Adenocarcinoma; DNA; Electrophoresis, Capillary; Fluorescent Antibody Technique; Humans; Hydrogen-Ion Concentration; Lung Neoplasms; Thymidine

2002
The reactivity of the 5-hydroxy-5,6-dihydrothymidin-6-yl radical in oligodeoxyribonucleotides.
    Chemical research in toxicology, 2005, Volume: 18, Issue:12

    Topics: Free Radicals; Gamma Rays; Hydroxyl Radical; Molecular Structure; Oligodeoxyribonucleotides; Organophosphorus Compounds; Single-Strand Specific DNA and RNA Endonucleases; Stereoisomerism; Thymidine; Ultraviolet Rays

2005
Synthesis and thermodynamic studies of oligodeoxyribonucleotides containing tandem lesions of thymidine glycol and 8-oxo-2'-deoxyguanosine.
    Chemical research in toxicology, 2006, Volume: 19, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Deoxyguanosine; Gas Chromatography-Mass Spectrometry; Molecular Structure; Oligodeoxyribonucleotides; Organophosphorus Compounds; Spectrometry, Mass, Electrospray Ionization; Thermodynamics; Thymidine

2006
Flavin-sensitized photoreduction of thymidine glycol.
    Bioorganic & medicinal chemistry letters, 2007, Nov-15, Volume: 17, Issue:22

    Topics: Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Molecular Structure; Oxidation-Reduction; Photochemistry; Thymidine; Ultraviolet Rays

2007
DNA tandem lesion repair by strand displacement synthesis and nucleotide excision repair.
    Biochemistry, 2008, Apr-08, Volume: 47, Issue:14

    Topics: DNA; DNA Polymerase beta; DNA Repair; Molecular Structure; Nucleotides; Phosphoric Diester Hydrolases; Thymidine; Transition Temperature

2008
Detection of DNA damage: effect of thymidine glycol residues on the thermodynamic, substrate and interfacial acoustic properties of oligonucleotide duplexes.
    The Analyst, 2009, Volume: 134, Issue:1

    Topics: Acoustics; Animals; Base Sequence; DNA Damage; Electrochemistry; Electrophoresis, Polyacrylamide Gel; Humans; Microscopy, Electron, Scanning Transmission; Molecular Sequence Data; Nucleic Acid Heteroduplexes; Oligodeoxyribonucleotides; Thermodynamics; Thymidine; Ultraviolet Rays

2009
In vitro replication and repair studies of tandem lesions containing neighboring thymidine glycol and 8-oxo-7,8-dihydro-2'-deoxyguanosine.
    Chemical research in toxicology, 2009, Mar-16, Volume: 22, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Deoxyguanosine; Deoxyribonuclease (Pyrimidine Dimer); DNA; DNA Damage; DNA Repair; DNA Repair Enzymes; DNA Replication; Guanine; Humans; Reactive Oxygen Species; Thymidine

2009
The mutagenicity of thymidine glycol in Escherichia coli is increased when it is part of a tandem lesion.
    Biochemistry, 2009, Aug-25, Volume: 48, Issue:33

    Topics: 5' Untranslated Regions; Bacteriophage M13; Dinucleotide Repeats; DNA Damage; DNA Repair; DNA, Bacterial; Escherichia coli; Genome, Bacterial; Hydroxyl Radical; Mutagenesis; Sequence Deletion; SOS Response, Genetics; Sugar Acids; Thymidine

2009
Evaluation of biomarkers of exposure and potential harm in smokers, former smokers and never-smokers.
    Clinical chemistry and laboratory medicine, 2009, Volume: 47, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Biomarkers; Cholesterol, LDL; Cross-Sectional Studies; Deoxyguanosine; Dinoprost; Female; Humans; Immunoglobulin G; Male; Middle Aged; Nicotine; Nitrosamines; Pyridines; Reproducibility of Results; Smoke; Smoking; Smoking Cessation; Thromboxane B2; Thymidine

2009
Kinetics of deamination and Cu(II)/H2O2/Ascorbate-induced formation of 5-methylcytosine glycol at CpG sites in duplex DNA.
    Nucleic acids research, 2009, Volume: 37, Issue:19

    Topics: Ascorbic Acid; Chromatography, Liquid; Copper; CpG Islands; Cytosine; Deamination; Deoxyribonucleotides; DNA; Hydrogen Peroxide; Kinetics; Tandem Mass Spectrometry; Thymidine

2009
Is thymidine glycol containing DNA a substrate of E. coli DNA mismatch repair system?
    PloS one, 2014, Volume: 9, Issue:8

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; DNA Cleavage; DNA Mismatch Repair; DNA Repair Enzymes; DNA-Binding Proteins; DNA, Bacterial; Endodeoxyribonucleases; Escherichia coli; Escherichia coli Proteins; Hydrolysis; MutL Proteins; MutS DNA Mismatch-Binding Protein; Plasmids; Protein Binding; Thymidine

2014
Reaction of Thymidine with Hypobromous Acid in Phosphate Buffer.
    Chemical & pharmaceutical bulletin, 2016, Volume: 64, Issue:8

    Topics: Bromates; Buffers; Molecular Structure; Phosphates; Stavudine; Thymidine

2016
In Vitro Bypass of Thymidine Glycol by DNA Polymerase θ Forms Sequence-Dependent Frameshift Mutations.
    Biochemistry, 2017, 12-26, Volume: 56, Issue:51

    Topics: DNA Damage; DNA Polymerase theta; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; Frameshift Mutation; Humans; Kinetics; Oxidative Stress; Thymidine

2017
Separation of Protactinium Employing Sulfur-Based Extraction Chromatographic Resins.
    Analytical chemistry, 2018, 06-05, Volume: 90, Issue:11

    Topics: Molecular Structure; Protactinium; Resins, Synthetic; Surface Properties; Thymidine; Uranium

2018
Enhanced Cleavage at Abasic Sites within Clustered Lesions in Nucleosome Core Particles.
    Chembiochem : a European journal of chemical biology, 2018, 10-04, Volume: 19, Issue:19

    Topics: DNA; DNA Damage; DNA Repair; Histones; Models, Molecular; Nucleic Acid Conformation; Nucleic Acid Denaturation; Nucleosomes; Thymidine

2018
Can plasma antioxidants prevent DNA damage in oxidative stress condition induced by growth hormone deficiency? A pilot study.
    PloS one, 2021, Volume: 16, Issue:4

    Topics: Adult; Case-Control Studies; DNA Damage; Female; Human Growth Hormone; Humans; Lymphocytes; Male; Middle Aged; Oxidative Stress; Pilot Projects; Thymidine

2021
DNA-Protein Cross-Linking Sequencing for Genome-Wide Mapping of Thymidine Glycol.
    Journal of the American Chemical Society, 2022, 01-12, Volume: 144, Issue:1

    Topics: Thymidine

2022