Page last updated: 2024-08-17

thymidine and thrombin aptamer

thymidine has been researched along with thrombin aptamer in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (75.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Aviñó, A; Eritja, R; Ferreira, R; Gargallo, R; Marquez, VE; Mazzini, S1
Bucci, M; Esposito, V; Galeone, A; Mayol, L; Petraccone, L; Scuotto, M; Varra, M; Vellecco, V; Virgilio, A1
Cai, B; Fan, X; Guan, Z; Jin, H; Li, L; Sun, L; Wu, Y; Yang, X; Yang, Z; Zhang, L1
Bucci, M; Esposito, V; Galeone, A; Irace, C; Mayol, L; Pepe, A; Petraccone, L; Santamaria, R; Varra, M; Vellecco, V; Virgilio, A1
Chai, Z; Du, S; Guo, L; He, J; Jin, H; Li, Y; Shi, W; Shi, Y; Wang, C1
Kolganova, NA; Smirnov, IP; Timofeev, EN; Tsvetkov, VB1
Bucci, M; Esposito, V; Galeone, A; Pecoraro, A; Pepe, A; Russo, A; Russo, G; Vellecco, V; Virgilio, A1
Kolganova, NA; Kurochkin, NN; Smirnov, IP; Stomakhin, AA; Surzhikov, SA; Timofeev, EN; Tsvetkov, VB; Varizhuk, IV1

Other Studies

8 other study(ies) available for thymidine and thrombin aptamer

ArticleYear
The effect on quadruplex stability of North-nucleoside derivatives in the loops of the thrombin-binding aptamer.
    Bioorganic & medicinal chemistry, 2012, Jul-15, Volume: 20, Issue:14

    Topics: Aptamers, Nucleotide; Circular Dichroism; Deoxyuracil Nucleotides; G-Quadruplexes; Nucleic Acid Conformation; Nucleic Acid Denaturation; Nucleosides; Temperature; Thermodynamics; Thymidine; Ultraviolet Rays; Uridine

2012
5-Hydroxymethyl-2'-deoxyuridine residues in the thrombin binding aptamer: investigating anticoagulant activity by making a tiny chemical modification.
    Chembiochem : a European journal of chemical biology, 2014, Nov-03, Volume: 15, Issue:16

    Topics: Anticoagulants; Aptamers, Nucleotide; Base Sequence; Circular Dichroism; Fibrinogen; Magnetic Resonance Spectroscopy; Models, Molecular; Protein Binding; Thrombin; Thymidine

2014
Stability and bioactivity of thrombin binding aptamers modified with D-/L-isothymidine in the loop regions.
    Organic & biomolecular chemistry, 2014, Nov-28, Volume: 12, Issue:44

    Topics: Aptamers, Nucleotide; G-Quadruplexes; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Stereoisomerism; Thrombin; Thymidine

2014
Site-specific replacement of the thymine methyl group by fluorine in thrombin binding aptamer significantly improves structural stability and anticoagulant activity.
    Nucleic acids research, 2015, Dec-15, Volume: 43, Issue:22

    Topics: Anticoagulants; Aptamers, Nucleotide; Circular Dichroism; Deoxyribonucleases; Fluorine; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleic Acid Denaturation; Prothrombin Time; Thermodynamics; Thymidine

2015
TBA loop mapping with 3'-inverted-deoxythymidine for fine-tuning of the binding affinity for α-thrombin.
    Organic & biomolecular chemistry, 2019, 02-27, Volume: 17, Issue:9

    Topics: Anticoagulants; Aptamers, Nucleotide; Base Sequence; Binding Sites; Circular Dichroism; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Nucleic Acid Conformation; Protein Binding; Temperature; Thrombin; Thymidine

2019
Probing the Nitroindole-Modified Central Loop of Thrombin Aptamer HD1 as a Recognition Site.
    Nucleic acid therapeutics, 2019, Volume: 29, Issue:4

    Topics: Anticoagulants; Aptamers, Nucleotide; G-Quadruplexes; Humans; Indoles; Molecular Dynamics Simulation; Nitro Compounds; Thymidine

2019
Structural properties and anticoagulant/cytotoxic activities of heterochiral enantiomeric thrombin binding aptamer (TBA) derivatives.
    Nucleic acids research, 2020, 12-16, Volume: 48, Issue:22

    Topics: Anticoagulants; Aptamers, Nucleotide; Circular Dichroism; G-Quadruplexes; Humans; Magnetic Resonance Spectroscopy; Protein Binding; Stereoisomerism; Thrombin; Thymidine

2020
Anticoagulant Oligonucleotide-Peptide Conjugates: Identification of Thrombin Aptamer Conjugates with Improved Characteristics.
    International journal of molecular sciences, 2022, Mar-30, Volume: 23, Issue:7

    Topics: Anticoagulants; Aptamers, Nucleotide; G-Quadruplexes; Nucleic Acids; Peptides; Thrombin; Thymidine

2022