Compounds > thymidine
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thymidine and thiophenes

thymidine has been researched along with thiophenes in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19905 (13.51)18.7374
1990's16 (43.24)18.2507
2000's10 (27.03)29.6817
2010's6 (16.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arredondo, MA; Guimaraes, MA; Rustum, YM; Yin, MB; Zhang, ZG1
Conroy, MC; Dong, MK; Gilbertsen, RB; Kossarek, LM; Kostlan, CR; Sircar, JC; Wilburn, DJ1
Davidson, NE; Gelmann, EP; Kasid, A; Lippman, ME1
Hirayama, Y; Katagiri, K; Katsuta, Y; Kurata, R; Matsushima, K; Nakamichi, K; Tsuchida, S; Yamaki, T; Yano, M1
Hotham-Iglewski, B; La Via, MF1
Boyd, JE; Sommerville, RG1
Shapiro, WR1
Cheng, ZJ; Kuo, SC; Yu, SM1
Cao, S; Rustum, YM; Yin, MB1
Rathod, PK; Reshmi, S1
Lehman, NL; Moran, RG; Smith, SG1
Keyomarsi, K; Molnar, G; Pardee, AB; Samet, J1
Cattaneo, E; Conti, E; Ma, ZQ; Maggi, A; Pollio, G; Santagati, S; Spreafico, E1
Catalioto, RM; Criscuoli, M; Giachetti, A; Porchia, R; Renzetti, AR; Subissi, A1
Canalis, E; Deloffre, P; Hott, M; Marie, PJ; Tsouderos, Y1
Hickman, JA; Jackman, AL; Potten, CS; Pritchard, DM; Watson, AJ1
Hung, LM; Lin, CC; Yu, SM1
Harris, AL; Patterson, AV; Stratford, IJ; Talbot, DC1
Frank, C; Guo, B; Panadero, A; Rustum, YM; Slocum, HK; Wrzosek, C; Yin, MB1
Campbell, GR; Campbell, JH; Fitzgerald, M; Hayward, IP; Thomas, AC1
Cao, S; McGuire, JJ; Rustum, YM1
Aherne, GW; Benstead, J; Clarke, SJ; Farrugia, DC; Jackman, AL; Pritchard, DM1
Danenberg, PV; Lehman, NL1
Genestier, L; Izeradjene, K; Revillard, JP1
Backus, HH; Bunni, MA; Comijn, L; Jackman, AL; Jansen, G; Mitchell, F; Peters, GJ; Priest, DG; Smid, K; van der Wilt, CL; Veerman, G; Voorn, DA; Wouters, D1
Faessel, HM; Greco, WR; Rustum, YM; Slocum, HK1
Banerjee, D; Bertino, JR; Li, WW; Magro, PG; Russo, AJ1
Antony, S; Gmeiner, WH; Kohlhagen, G; Liao, ZY; Pommier, Y; Sordet, O; Zhang, HL1
Boddy, AV; Graham-Cole, CL; Hesp, R; Melton, RG; Newell, DR; Taylor, GA; Thomas, HD1
Cassidy, J; Collie-Duguid, ES; McLeod, HL; Wang, W1
Alesi, S; Barbarella, G; Brancolini, G; Camaioni, N; Capobianco, ML; Melucci, M; Venturini, A1
Boddy, AV; Heer, R; Karran, P; Newell, DR; O'Toole, K; Pridgeon, SW; Robinson, M; Taylor, GA; Xu, YZ1
Bortolatto, CF; Jesse, CR; Nogueira, CW; Rambo, LM; Ribeiro, LR; Roman, SS; Royes, LF; Wilhelm, EA1
Ghosh, D; McMahon, MA; Seiple, L; Siliciano, RF; Spivak, AM; Stivers, JT; Weil, AF; Zhou, Y1
Andrei, G; Balzarini, J; Drillien, R; Duraffour, S; Haraguchi, K; Snoeck, R; Topalis, D; van den Oord, JJ1
Andrei, G; Balzarini, J; Coen, N; Duraffour, S; Haraguchi, K; Snoeck, R; van den Oord, JJ1
An, H; Niu, R; Xing, C; Xu, S; Yuan, H; Zhan, Y1

Other Studies

37 other study(ies) available for thymidine and thiophenes

ArticleYear
Time dependence of DNA lesions and growth inhibition by ICI D1694, a new quinazoline antifolate thymidylate synthase inhibitor.
    Cancer research, 1992, Nov-01, Volume: 52, Issue:21

    Topics: Cell Division; Cell Line; DNA; DNA Damage; DNA, Single-Stranded; Fluorouracil; Formyltetrahydrofolates; Methotrexate; Quinazolines; Rhodamines; Thiophenes; Thymidine; Thymidylate Synthase; Time Factors

1992
Biochemical and pharmacological properties of CI-972, a novel 9-deazaguanine analog purine nucleoside phosphorylase (PNP) inhibitor.
    Advances in experimental medicine and biology, 1991, Volume: 309A

    Topics: Animals; Cell Line; Cells, Cultured; Deoxyguanine Nucleotides; Guanosine Triphosphate; Humans; Lymphocytes; Male; Nucleosides; Purine-Nucleoside Phosphorylase; Pyrimidines; Rats; Rats, Inbred Strains; Thiophenes; Thymidine

1991
Transcriptional control of thymidine kinase gene expression by estrogen and antiestrogens in MCF-7 human breast cancer cells.
    The Journal of biological chemistry, 1986, Apr-25, Volume: 261, Issue:12

    Topics: Amanitins; Breast Neoplasms; Cell Cycle; Cell Line; DNA; Estradiol; Estrogen Antagonists; Estrogens; Gene Expression Regulation; Humans; Methylation; Pyrrolidines; RNA; RNA, Messenger; Tamoxifen; Thiophenes; Thymidine; Thymidine Kinase; Time Factors

1986
Stimulation of rat liver growth by a 1,3-dithiole derivative, KZ-1026.
    Japanese journal of pharmacology, 1989, Volume: 50, Issue:2

    Topics: Animals; Cell Nucleus; DNA; Galactose; Hepatectomy; Ketones; Liver; Liver Function Tests; Male; Phenobarbital; Rats; Rats, Inbred Strains; Thiophenes; Thymidine

1989
Effect of beta-3-thienylalanine on antibody synthesis. 3. Inhibition of RNA and protein synthesis in immunized rat spleen cells.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1969, Volume: 131, Issue:3

    Topics: Alanine; Animals; Antibody Formation; Carbon Isotopes; Depression, Chemical; Electrophoresis, Disc; gamma-Globulins; Male; Phenylalanine; Protein Biosynthesis; Rats; RNA; Spleen; Thiophenes; Thymidine; Tritium; Uridine

1969
The antiviral activity of some related benzo(b) thiophene derivatives. III. Anti-vaccinia activity.
    Archiv fur die gesamte Virusforschung, 1974, Volume: 46, Issue:1-2

    Topics: Antiviral Agents; Autoradiography; Cell Nucleus; Chemical Phenomena; Chemistry; DNA, Viral; Fluorescent Antibody Technique; Guanidines; HeLa Cells; Humans; Idoxuridine; Morpholines; Pyrrolidines; Thiophenes; Thymidine; Time Factors; Tritium; Uridine; Vaccinia virus; Virus Replication

1974
The chemotherapy of intracerebral vs subcutaneous murine gliomas. A comparative study of the effect of VM 26.
    Archives of neurology, 1974, Volume: 30, Issue:3

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Disease Models, Animal; DNA, Neoplasm; Ependymoma; Glycosides; Injections; Injections, Subcutaneous; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Podophyllotoxin; Thiophenes; Thymidine; Tritium

1974
Antiproliferative effects of A02011-1, an adenylyl cyclase activator, in cultured vascular smooth muscle cells of rat.
    British journal of pharmacology, 1995, Volume: 114, Issue:6

    Topics: Adenylyl Cyclases; Animals; Cell Division; Cells, Cultured; Cyclic AMP; Cyclic GMP; Enzyme Activation; Male; Mitogens; Muscle, Smooth, Vascular; Pyrazoles; Rats; Rats, Wistar; Stimulation, Chemical; Thiophenes; Thymidine

1995
Modulation of target enzyme associated with the action of antifolates.
    Advances in enzyme regulation, 1994, Volume: 34

    Topics: Antimetabolites, Antineoplastic; Carcinoma; Dose-Response Relationship, Drug; Drug Interactions; Evaluation Studies as Topic; Humans; Intestinal Neoplasms; Leucovorin; Quinazolines; Thiophenes; Thymidine; Thymidylate Synthase; Tumor Cells, Cultured

1994
Susceptibility of Plasmodium falciparum to a combination of thymidine and ICI D1694, a quinazoline antifolate directed at thymidylate synthase.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:3

    Topics: Animals; Antimalarials; Cell Division; Erythrocytes; Folic Acid Antagonists; HeLa Cells; Humans; In Vitro Techniques; Mice; Plasmodium falciparum; Quinazolines; Thiophenes; Thymidine; Thymidylate Synthase; Tumor Cells, Cultured

1994
Cytotoxicity of antifolate inhibitors of thymidylate and purine synthesis to WiDr colonic carcinoma cells.
    Cancer research, 1993, Dec-01, Volume: 53, Issue:23

    Topics: Acyltransferases; Antineoplastic Agents; Cell Division; Cell Survival; Colonic Neoplasms; Folic Acid Antagonists; Humans; Hydroxymethyl and Formyl Transferases; Hypoxanthine; Hypoxanthines; Methotrexate; Phosphoribosylglycinamide Formyltransferase; Quinazolines; Tetrahydrofolates; Thiophenes; Thymidine; Thymidylate Synthase; Tumor Cells, Cultured

1993
The thymidylate synthase inhibitor, ICI D1694, overcomes translational detainment of the enzyme.
    The Journal of biological chemistry, 1993, Jul-15, Volume: 268, Issue:20

    Topics: Cell Cycle; Cell Division; Cells, Cultured; Cycloheximide; Enzyme Stability; Humans; Protein Biosynthesis; Quinazolines; RNA, Messenger; Thiophenes; Thymidine; Thymidylate Synthase; Tumor Cells, Cultured

1993
Activated estrogen receptor mediates growth arrest and differentiation of a neuroblastoma cell line.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Apr-15, Volume: 90, Issue:8

    Topics: Cell Differentiation; Cell Division; Chloramphenicol O-Acetyltransferase; Estradiol; Estrogen Antagonists; Humans; Kinetics; Neuroblastoma; Pyrrolidines; Receptors, Estrogen; Recombinant Fusion Proteins; Thiophenes; Thymidine; Time Factors; Transfection; Tumor Cells, Cultured

1993
Angiotensin II-induced responses in vascular smooth muscle cells: inhibition by non-peptide receptor antagonists.
    European journal of pharmacology, 1995, Jul-14, Volume: 280, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Biphenyl Compounds; Cells, Cultured; Dinoprostone; DNA; Epoprostenol; Imidazoles; Inositol 1,4,5-Trisphosphate; Leucine; Losartan; Male; Muscle, Smooth, Vascular; Protein Biosynthesis; Pyridines; Pyrimidinones; Rats; Rats, Sprague-Dawley; Tetrazoles; Thiophenes; Thymidine

1995
The divalent strontium salt S12911 enhances bone cell replication and bone formation in vitro.
    Bone, 1996, Volume: 18, Issue:6

    Topics: Animals; Animals, Newborn; Bone Density; Bone Development; Cell Division; Cells, Cultured; Collagen; Fibroblasts; Isotope Labeling; Organometallic Compounds; Osteoblasts; Rats; Rats, Sprague-Dawley; Stem Cells; Thiophenes; Thymidine; Uncoupling Agents

1996
Inhibition by uridine but not thymidine of p53-dependent intestinal apoptosis initiated by 5-fluorouracil: evidence for the involvement of RNA perturbation.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Mar-04, Volume: 94, Issue:5

    Topics: Animals; Apoptosis; Colon; Enzyme Inhibitors; Fluorouracil; Folic Acid Antagonists; Gene Expression Regulation; Histocytochemistry; Immunohistochemistry; Intestinal Mucosa; Intestine, Small; Male; Mice; Mice, Inbred Strains; Quinazolines; RNA; Thiophenes; Thymidine; Thymidylate Synthase; Tumor Suppressor Protein p53; Uridine

1997
cGMP-elevating agents suppress proliferation of vascular smooth muscle cells by inhibiting the activation of epidermal growth factor signaling pathway.
    Circulation, 1997, Mar-04, Volume: 95, Issue:5

    Topics: Amino Acid Sequence; Animals; Antibodies; Aorta; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Cyclic AMP; Cyclic GMP; DNA; Epidermal Growth Factor; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; L-Lactate Dehydrogenase; Molecular Sequence Data; Muscle, Smooth, Vascular; Nitroprusside; Peptide Fragments; Phosphodiesterase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Pyrazoles; ras Proteins; Rats; Signal Transduction; Thiophenes; Thymidine

1997
Thymidine phosphorylase moderates thymidine-dependent rescue after exposure to the thymidylate synthase inhibitor ZD1694 (Tomudex) in vitro.
    Cancer research, 1998, Jul-01, Volume: 58, Issue:13

    Topics: Antimetabolites, Antineoplastic; Breast Neoplasms; Culture Media, Conditioned; Dose-Response Relationship, Drug; Female; Humans; Quinazolines; Thiophenes; Thymidine; Thymidine Phosphorylase; Thymidylate Synthase; Time Factors; Transfection; Tumor Cells, Cultured

1998
Cyclin E-cdk2 activation is associated with cell cycle arrest and inhibition of DNA replication induced by the thymidylate synthase inhibitor Tomudex.
    Experimental cell research, 1999, Feb-25, Volume: 247, Issue:1

    Topics: Carrier Proteins; CDC2-CDC28 Kinases; Cell Cycle; Cell Cycle Proteins; Cyclin A; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; DNA; DNA Fragmentation; DNA-Binding Proteins; DNA, Neoplasm; E2F Transcription Factors; E2F1 Transcription Factor; Enzyme Activation; Enzyme Inhibitors; Growth Inhibitors; Humans; Macromolecular Substances; Protein Serine-Threonine Kinases; Quinazolines; Retinoblastoma-Binding Protein 1; Thiophenes; Thymidine; Thymidylate Synthase; Transcription Factor DP1; Transcription Factors; Tumor Cells, Cultured

1999
Matrix metalloproteinase can facilitate the heparanase-induced promotion of phenotype change in vascular smooth muscle cells.
    Atherosclerosis, 1999, Volume: 145, Issue:1

    Topics: Actin Cytoskeleton; Animals; Arteriosclerosis; Carotid Arteries; Catheterization; Cell Division; Coculture Techniques; DNA; Glucuronidase; Glycoside Hydrolases; Humans; Macrophages; Metalloendopeptidases; Muscle, Smooth, Vascular; Phenotype; Phenylalanine; Rabbits; Thiophenes; Thymidine

1999
Antitumor activity of ZD1694 (tomudex) against human head and neck cancer in nude mouse models: role of dosing schedule and plasma thymidine.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:7

    Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Drug Administration Schedule; Female; Floxuridine; Fluorouracil; Head and Neck Neoplasms; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Quinazolines; Thiophenes; Thymidine; Transplantation, Heterologous; Tumor Cells, Cultured

1999
Balb/c mice as a preclinical model for raltitrexed-induced gastrointestinal toxicity.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Deoxyuridine; Diarrhea; Digestive System; Dose-Response Relationship, Drug; Folic Acid; Intestinal Mucosa; Intestine, Large; Intestine, Small; Male; Maximum Tolerated Dose; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Quinazolines; Thiophenes; Thymidine; Thymidylate Synthase; Weight Loss

2000
Modulation of RTX cytotoxicity by thymidine and dipyridamole in vitro: implications for chemotherapy.
    Cancer chemotherapy and pharmacology, 2000, Volume: 45, Issue:2

    Topics: Antimetabolites, Antineoplastic; Colorectal Neoplasms; Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Genes, p53; Humans; Phosphodiesterase Inhibitors; Quinazolines; Thiophenes; Thymidine; Tumor Cells, Cultured

2000
Inhibition of thymidine synthesis by folate analogues induces a Fas-Fas ligand-independent deletion of superantigen-reactive peripheral T cells.
    International immunology, 2001, Volume: 13, Issue:1

    Topics: Animals; CD8-Positive T-Lymphocytes; Clonal Deletion; Enterotoxins; Fas Ligand Protein; fas Receptor; Folic Acid Antagonists; Growth Inhibitors; Injections, Intraperitoneal; Injections, Intravenous; Ligands; Lymphocyte Activation; Lymphocyte Depletion; Membrane Glycoproteins; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred MRL lpr; Nucleic Acid Synthesis Inhibitors; Quinazolines; Staphylococcus aureus; Superantigens; T-Lymphocyte Subsets; Thiophenes; Thymidine; Thymidylate Synthase

2001
Modulation of both endogenous folates and thymidine enhance the therapeutic efficacy of thymidylate synthase inhibitors.
    Cancer research, 2001, May-01, Volume: 61, Issue:9

    Topics: Animals; Antimetabolites, Antineoplastic; Cell Division; Colonic Neoplasms; Diet; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Female; Fluorouracil; Folic Acid; Folic Acid Antagonists; Glutamates; Guanine; Leucovorin; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Pemetrexed; Quinazolines; Thiophenes; Thymidine; Thymidine Kinase; Thymidylate Synthase

2001
Thymidine and hypoxanthine protection patterns of the folic acid-enhanced synergies for combinations of trimetrexate plus a polyglutamylatable inhibitor of purine or thymidylate synthesis against human ileocecal HCT-8 cells.
    International journal of oncology, 2003, Volume: 23, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cecal Neoplasms; Cell Division; Drug Resistance, Multiple; Drug Synergism; Enzyme Inhibitors; Folic Acid; Glutamates; Hematinics; Humans; Hydroxymethyl and Formyl Transferases; Hypoxanthine; Ileal Neoplasms; Peptide Synthases; Phosphoribosylglycinamide Formyltransferase; Pyrimidines; Quinazolines; Thiophenes; Thymidine; Thymidylate Synthase; Trimetrexate; Tumor Cells, Cultured

2003
p14ARF expression increases dihydrofolate reductase degradation and paradoxically results in resistance to folate antagonists in cells with nonfunctional p53.
    Cancer research, 2004, Jun-15, Volume: 64, Issue:12

    Topics: Cell Division; Cell Line, Tumor; Drug Resistance, Neoplasm; Enzyme Stability; Fibrosarcoma; Folic Acid Antagonists; Humans; Methotrexate; Neoplastic Stem Cells; Quinazolines; Tetrahydrofolate Dehydrogenase; Thiophenes; Thymidine; Thymidylate Synthase; Trimetrexate; Tumor Suppressor Protein p14ARF; Tumor Suppressor Protein p53

2004
A novel polypyrimidine antitumor agent FdUMP[10] induces thymineless death with topoisomerase I-DNA complexes.
    Cancer research, 2005, Jun-01, Volume: 65, Issue:11

    Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Death; DNA Damage; DNA Topoisomerases, Type I; DNA, Neoplasm; DNA, Single-Stranded; Drug Screening Assays, Antitumor; Fluorodeoxyuridylate; Fluorouracil; Leukemia P388; Mice; Quinazolines; Thiophenes; Thymidine; Thymidylate Synthase; Topoisomerase I Inhibitors

2005
An evaluation of thymidine phosphorylase as a means of preventing thymidine rescue from the thymidylate synthase inhibitor raltitrexed.
    Cancer chemotherapy and pharmacology, 2007, Volume: 59, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Carcinoembryonic Antigen; Cell Line, Tumor; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; HT29 Cells; Humans; Immunoglobulin Fab Fragments; Injections, Intravenous; Mice; Mice, Nude; Quinazolines; Reproducibility of Results; Thiophenes; Thymidine; Thymidine Phosphorylase; Thymidylate Synthase; Xenograft Model Antitumor Assays

2007
Mechanisms of acquired chemoresistance to 5-fluorouracil and tomudex: thymidylate synthase dependent and independent networks.
    Cancer chemotherapy and pharmacology, 2007, Volume: 59, Issue:6

    Topics: Antimetabolites, Antineoplastic; Drug Resistance, Neoplasm; Fluorouracil; Humans; NF-kappa B; Quinazolines; Thiophenes; Thymidine; Thymidylate Synthase; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2007
Water-soluble, electroactive, and photoluminescent quaterthiophene-dinucleotide conjugates.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2008, Volume: 14, Issue:2

    Topics: Adenosine; Electrochemistry; Hydrogen Bonding; Luminescence; Luminescent Measurements; Models, Molecular; Molecular Structure; Nucleotides; Photochemistry; Solubility; Spectrophotometry, Ultraviolet; Stereoisomerism; Thiophenes; Thymidine; Water

2008
Thiothymidine combined with UVA as a potential novel therapy for bladder cancer.
    British journal of cancer, 2011, Jun-07, Volume: 104, Issue:12

    Topics: Animals; Apoptosis; Cell Line, Tumor; DNA Damage; Female; Humans; Quinazolines; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Thiophenes; Thymidine; Ultraviolet Therapy; Urinary Bladder Neoplasms

2011
Protective effect of 2,2'-dithienyl diselenide on kainic acid-induced neurotoxicity in rat hippocampus.
    Neuroscience, 2011, Oct-13, Volume: 193

    Topics: Analysis of Variance; Animals; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Glutathione Peroxidase; Hippocampus; Kainic Acid; Male; Neuroprotective Agents; Neurotoxicity Syndromes; Neurotoxins; Organoselenium Compounds; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Reaction Time; Seizures; Sodium-Potassium-Exchanging ATPase; Sulfhydryl Compounds; Thiophenes; Thymidine; Trityl Compounds

2011
Uracil DNA glycosylase initiates degradation of HIV-1 cDNA containing misincorporated dUTP and prevents viral integration.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Feb-05, Volume: 110, Issue:6

    Topics: Anti-HIV Agents; Base Sequence; CD4-Positive T-Lymphocytes; Deoxyuracil Nucleotides; DNA Glycosylases; DNA, Viral; Enzyme Inhibitors; Gene Knockdown Techniques; HIV-1; Host-Pathogen Interactions; HT29 Cells; Humans; Immunity, Innate; Macrophages; Models, Biological; Mutation; Quinazolines; Reverse Transcription; Thiophenes; Thymidine; Thymidylate Synthase; Virion; Virus Integration

2013
KAY-2-41, a novel nucleoside analogue inhibitor of orthopoxviruses in vitro and in vivo.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:1

    Topics: Antiviral Agents; Cowpox virus; Genotype; Molecular Structure; Orthopoxvirus; Thiophenes; Thymidine; Vaccinia virus

2014
Antiherpesvirus activities of two novel 4'-thiothymidine derivatives, KAY-2-41 and KAH-39-149, are dependent on viral and cellular thymidine kinases.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:8

    Topics: Animals; Antiviral Agents; Drug Resistance, Viral; Enzyme Assays; HeLa Cells; Herpesviridae Infections; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Herpesvirus 4, Human; Host-Pathogen Interactions; Humans; Mice; Mutation; NIH 3T3 Cells; Phosphorylation; Thionucleosides; Thiophenes; Thymidine; Thymidine Kinase; Viral Proteins

2014
Nucleobase-functionalized conjugated polymer for detection of copper(II).
    ACS applied materials & interfaces, 2014, Jun-25, Volume: 6, Issue:12

    Topics: Copper; DNA; Fluorescence; Ions; Phosphates; Polymers; Spectrometry, Fluorescence; Thiophenes; Thymidine; Water

2014