thymidine has been researched along with telbivudine in 390 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 95 (24.36) | 29.6817 |
| 2010's | 293 (75.13) | 24.3611 |
| 2020's | 2 (0.51) | 2.80 |
| Authors | Studies |
|---|---|
| Hodge, RA | 1 |
| Lok, AS | 1 |
| Brown, NA; Chao, GC; Lai, CL; Lee, YM; Lim, SG; Lloyd, DM; Myers, MW; Yuen, MF; Zhou, XJ | 1 |
| Han, SH | 1 |
| Brown, NA; Chao, G; Han, S; Hann, HW; Lai, CL; Leung, N; Lloyd, D; Myers, M; Poynard, T; Teo, EK; Tong, M; Wong, F | 1 |
| Lai, CL; Yuen, MF | 1 |
| Brown, NA; Chao, GC; Lloyd, DM; Zhou, XJ | 1 |
| Brown, NA; Chao, GC; Lai, CL; Lim, SG; Lloyd, DM; Zhou, XJ | 1 |
| Kim, JW; Louie, SG; Park, SH | 1 |
| Alcorn, HW; Brown, NA; Chao, GC; Dubuc Patrick, G; Marbury, TC; Smith, WB; Zhou, XJ | 1 |
| Brown, NA; Chao, GC; Fielman, BA; Lloyd, DM; Zhou, XJ | 1 |
| Brown, NA; Chao, GC; Hu, P; Jiang, J; Pietropaolo, K; Wang, H; Zhou, XJ | 1 |
| Jones, R; Nelson, M | 1 |
| Brown, NA; Hu, P; Jiang, J; Shen, K; Wang, HY; Zhou, XJ | 1 |
| Lu, ZM; Xu, J | 1 |
| Gish, RG | 1 |
| Dienstag, J; Easley, C; Kirkpatrick, P | 1 |
| Ruiz-Sancho, A; Sheldon, J; Soriano, V | 1 |
| Hadziyannis, SJ | 1 |
| Chen, CW; Chen, YG; He, YW; Hou, JL; Jia, JD; Ma, H; Niu, JQ; Ren, H; Tan, DM; Wan, MB; Wang, QH; Wang, YM; Wei, L; Wu, SM; Xu, DZ; Xu, JZ; Yin, YK; Zhou, XQ; Zhu, LM | 1 |
| Pham, PA; Thio, C | 1 |
| Garcia-Gasco, P; Sheldon, J; Soriano, V | 1 |
| Keam, SJ | 1 |
| Danta, M; Dusheiko, G | 1 |
| Brown, NA; Chao, GC; Dubuc-Patrick, G; Marbury, TC; Smith, WB; Swan, S; Zhou, XJ | 1 |
| Niederau, C | 1 |
| Brown, NA; Bzowej, N; Chan, HL; Chao, YC; Cho, M; Harb, G; Heathcote, EJ; Jeffers, L; Kaiser, R; Lai, CL; Marcellin, P; Minuk, GY; Moon, YM; Myers, RP; Qiao, XJ; Sievert, W | 1 |
| Hou, JL; Sun, J; Wang, C | 1 |
| Gaeta, GB; Stornaiuolo, G | 1 |
| Alexandre, JA; Deville-Bonne, D; Périgaud, C; Roy, B; Topalis, D | 1 |
| Amarapurkar, DN | 1 |
| Brown, NA; Chao, G; Chen, C; Chen, Y; Constance, BF; Harb, G; He, Y; Hou, J; Jia, J; Niu, J; Ren, H; Tan, D; Wan, M; Wang, Q; Wang, Y; Wei, L; Wu, S; Xu, D; Xu, J; Yin, YK; Zhou, X; Zhu, L | 1 |
| Brown, NA; Bzowej, N; Chao, G; Chen, Y; Constance, BF; Di Bisceglie, AM; Gane, E; Goodman, Z; Heathcote, EJ; Hsu, CW; Lai, CL; Liaw, YF; Moon, YM; Naoumov, NV; Rasenack, J; Thongsawat, S; Wang, Y; Zeuzem, S | 1 |
| Ahn, SH; Cho, M; Choi, HS; Han, JY; Hwang, SG; Kim, BS; Kim, DJ; Kim, YS; Moon, YM; Rim, KS | 1 |
| Matthews, SJ | 1 |
| Hann, HW | 2 |
| Sánchez-Tapias, JM | 1 |
| Goto, T; Kato, N; Omata, M | 1 |
| McHutchison, JG; Tillmann, HL | 1 |
| Mauss, S | 1 |
| Butí, MA | 1 |
| Ayoub, WS; Keeffe, EB | 1 |
| Bridges, EG; Luo, S; Selden, JR | 1 |
| Jin, R; Tao, ML; Zhang, SB; Zhang, XS | 1 |
| Chawla, PS; Kochar, MS | 1 |
| Yim, HJ | 1 |
| Brett, S; Chokshi, S; Cooksley, H; Evans, A; Naoumov, NV; Nathwani, A; Phillips, S; Puranik, S; Riva, A | 1 |
| Chan, HL; Lui, YY | 2 |
| Beckebaum, S; Cicinnati, VR; Gerken, G; Sotiropoulos, GC | 1 |
| Guo, SH; He, H; Ren, H; Shi, KQ; Shi, XF; Wang, ZY; Zeng, WQ; Zhang, DZ | 1 |
| Albanis, E; Brown, NA; Bzowej, N; Cakaloglu, Y; Chen, Y; Galil, K; Gane, E; Han, SH; Heathcote, EJ; Hwang, SG; Lai, CL; Leung, N; Liaw, YF; Manns, M; Naoumov, NV; Niu, J; Papatheodoridis, G; Tong, MJ; Wang, Y; Zeuzem, S | 1 |
| Li, B; Patty, A; Seifer, M; Serra, I; Standring, DN | 1 |
| Hadziyannis, SJ; Vassilopoulos, D | 1 |
| Andersen, ES; Weis, NM | 1 |
| García Buey, L; González Mateos, F; Moreno Otero, R | 1 |
| Buti, M | 2 |
| González-Diéguez, ML; Rodríguez, M | 1 |
| Barreiro, P; García-Samaniego, J; Martín-Carbonero, L | 1 |
| Chen, M; Pan, XC; Yang, F | 1 |
| Fontana, RJ | 1 |
| Chien, RN; Liaw, YF | 1 |
| Buster, EH; Janssen, HL; Schalm, SW | 1 |
| Han, T; Liang, J; Xiao, SX | 1 |
| Colombo, M; Lampertico, P | 1 |
| Nash, K | 1 |
| Keeffe, EB; Nguyen, MH | 1 |
| Atkins, M; Cox, A; Low, E; Nelson, M | 1 |
| Amini-Bavil-Olyaee, S; Herbers, U; Luedde, T; Sheldon, J; Tacke, F; Trautwein, C | 1 |
| Liaw, YF | 1 |
| Iun', F | 1 |
| Chen, M; Guo, SH; He, H; Zhang, DZ; Zhang, L | 1 |
| Dusheiko, GM; Jacobs, MG | 1 |
| Bao, W; Belanger, B; Buti, M; Chutaputti, A; DiBisceglie, A; Gane, E; Hou, J; Jia, J; Liaw, YF; Lim, SG; Naoumov, NV; Nguyen, TT; O'Brien, C; Poynard, T; Rasenack, J; Zeuzem, S | 1 |
| Borroto-Esoda, K; Curtis, M; Miller, MD; Qi, X; Zhu, Y | 1 |
| Farrell, C; Ke, J; Mayers, DL; Pentikis, HS; Sallas, WM; Zhou, XJ | 1 |
| Janssen, HL; Reijnders, JG | 1 |
| ZHUANG, H | 1 |
| Cong, M; Jia, J; Li, H; Liu, T; Ma, H; Ou, X; Ren, J; Wang, B; Wang, P; Wang, X; You, H | 1 |
| Fleischer, RD; Lok, AS | 1 |
| Wang, L; Zhang, LJ | 1 |
| Chen, W; Hou, JL | 1 |
| Barreiro, P; Fernández, JV; Labarga, P; Medrano, J; Soriano, V; Tuma, P; Vispo, E | 1 |
| Balotta, C; Caramma, I; Cesari, M; De Maddalena, C; Galli, M; Lai, A; Milazzo, L; Violin, M | 1 |
| Harris, SI; Ke, J; Mayers, D; Poordad, F; Xu, L; Zeldin, G; Zhou, XJ | 1 |
| Cooper, K; Harris, P; Hartwell, D; Jones, J | 1 |
| Lin, Q; Zhang, DZ | 1 |
| Chang, JB; Wang, JF; Xue, R | 1 |
| Avila, C; Bao, W; Herrmann, E; Kim, JH; Lee, HC; Lee, HJ; Lee, MS; Lee, YJ; Lee, YS; Lopez, P; Suh, DJ; Um, SH; Zeuzem, S | 1 |
| Duong, A; Mousa, SA | 1 |
| Chiarenza, A; Di Raimondo, F; Fatuzzo, F; Iacobello, C; La Rosa, R; Larocca, L; Montineri, A; Nigro, L | 1 |
| Marcellin, P; Perrillo, RP | 1 |
| An, B; Bao, S; Cai, W; Gu, R; Guo, Q; Wang, H; Xie, Q; Zhao, G; Zhou, X | 1 |
| Avila, C; Evans, TG; Karwowska, S; Lam, E; Limoli, K; Lin, K | 1 |
| Chan, HL; Han, KH; Hou, JL; Kao, JH; Lui, YY; Mihm, U; Mohamed, R; Piratvisuth, T; Teo, EK; Tsoi, KK; Wong, GL; Wong, VW | 1 |
| Chen, EQ; Dai, J; Gao, Z; Lei, J; Liu, C; Liu, FJ; Liu, L; Tang, H; Xu, L; Zhou, TY | 1 |
| Chee, GM; Poordad, F | 1 |
| Chen, YP; Dai, ZJ; Shi, KQ; Ye, C; Zheng, MH | 1 |
| Guo, HH; Ji, SW; Jiao, J; Li, Y; Siqingtu, NL; Wang, JB; Xu, Y; Zhang, YG; Zhao, P; Zhou, CY | 1 |
| Bao, H; Furman, PA; Korba, B; Micolochick Steuer, HM; Murakami, E; Niu, C; Tolstykh, T | 1 |
| Chien, RN | 1 |
| Chen, H; Li, T; Shen, J; Wu, B | 1 |
| Chen, T; Guo, W; Lu, YL; Luo, XP; Ning, Q; Wang, HW; Wang, XJ; Wu, ZG; Yan, WM; Yang, XJ; Zou, Y | 1 |
| Caprio, N; Coppola, N; Iodice, V; Macera, M; Masiello, A; Pasquale, G; Tonziello, G | 1 |
| But, DY; Fung, J; Lai, CL; Yuen, MF | 1 |
| Jin, X; Lv, GC; Ma, WJ; Yang, YD; Ying, LJ; Zheng, L | 1 |
| Jin, X; Li, L; Lv, G; Ma, WJ; Yang, Y; Ying, L; Zheng, L | 1 |
| Chen, L; Dai, X; Fan, X; Tang, L; Zhao, S; Zhou, R | 1 |
| Gong, HY; Liu, ZG; Zhang, HY; Zhang, Z | 1 |
| Keam, SJ; McKeage, K | 1 |
| Bao, W; Goodman, ZD; Jung, M; Lopez, P; Manns, MP; Naoumov, NV; Riva, A; Wedemeyer, H; Wursthorn, K | 1 |
| Chen, FJ; Chong, YT; Deng, H; Gao, ZL; Lin, BL; Xie, DY; Zhang, XH | 1 |
| Chen, Y; Hwang, SG; Jia, JD; Lopez, P; Safadi, R; Wei, L; Xie, Q; Yin, YK; Zuckerman, E | 1 |
| Ge, SF; Guo, WW; Hu, JG; Jiang, JN; Jiang, ZC; Liang, YX; Liu, ZH; Su, MH; Zhu, MQ | 1 |
| Ay, L; Finsterer, J | 1 |
| Bourlière, M; Kahloun, A; Zoulim, F | 1 |
| Benhamou, Y; Pais, R | 1 |
| Abbott, WG; Hou, JL; Huang, X; Li, C; Li, YY; Ma, SW; Sun, J; Zhang, GW | 1 |
| Fung, J; Hung, IF; Lai, CL; Seto, WK; Wong, DK; Yuen, JC; Yuen, MF | 1 |
| Abuduheilili, X; Dong, JP; Hou, CS; Jiao, XJ; Li, T; Li, XG; Liu, BM; Sun, XW; Wang, YH; Xu, J; Yan, CH; Yan, L; Yang, JX; Zhuang, H | 1 |
| Leung, N | 1 |
| Papatheodoridis, GV | 1 |
| Zoulim, F | 1 |
| Mallet, V; Pol, S; Vallet-Pichard, A | 1 |
| Bai, XF; Gou, YZ; Jiang, W; Liu, B; Yu, HT | 1 |
| Cornberg, M; Darnedde, M; Jaroszewicz, J; Manns, MP; Mederacke, I; Raupach, R; Wedemeyer, H; Wursthorn, K; Zacher, BJ | 1 |
| Cao, H; Chen, LB; Chen, N; Li, G; Shu, X; Xu, QH; Zhang, K; Zhang, YF | 1 |
| Dai, J; Ji, D; Li, L; Li, X; Liu, Y; Ren, X; Wang, C; Wang, L; Wong, VW; Xu, D; Xu, Z; Yao, Z; Zhang, L; Zhong, Y; Zoulim, F | 1 |
| Akarca, US; Yurdaydin, C | 1 |
| Avila, C; Bao, W; Chao, YC; Gane, EJ; Hou, J; Hsu, CW; Jia, J; Leung, N; Liaw, YF; Lopez, P; Moon, YM; Niu, J; Samuel, D; Thongsawat, S; Wan, M; Wang, Y | 1 |
| Cho, YK; Song, BC | 1 |
| Cao, H; Chen, B; Chen, Y; Li, L; Li, X; Pan, X; Wu, W; Yang, X; Ye, B | 1 |
| Cong, M; Jia, J; Liu, T; Ma, H; Ou, X; Wang, B; Wang, P; Wang, Q; Wu, X; You, H | 1 |
| Tornai, I | 1 |
| Chen, R; Chen, WL; Chen, XF; Chen, XP; Huang, J; Luo, XD; Ma, XJ | 1 |
| Dang, S; Gao, N; Jia, X; Zhang, X | 1 |
| Bai, SF; Cao, MK; Fang, ZX; Han, GR; Jiang, HX; Tang, X; Wang, CM; Wang, GJ; Yue, X; Zhao, W | 1 |
| Petersen, J | 1 |
| Chen, CB; Chen, M; Ren, H; Shi, TD; Sun, H; Wang, XF; Zhang, JM | 1 |
| Giles, M; Sasadeusz, J; Visvanathan, K | 1 |
| Razonable, RR | 1 |
| Arends, JE; Beilhartz, GL; de Jong, D; Götte, M; Hoepelman, AI; Nijhuis, M; Obikhod, A; Pingen, M; Schinazi, RF; Tao, S; van Maarseveen, NM; Wensing, AM | 1 |
| Jiang, XQ; Tian, DY; Zou, XJ | 1 |
| Suzuki, F | 2 |
| García-Alonso, FJ; Martín-Mateos, RM; Moreira Vicente, V | 1 |
| Abbott, WG; Dong, YH; Hou, JL; Huang, X; Jiang, XT; Li, YY; Liu, ZH; Ma, SW; Naoumov, NV; Sun, J; Sun, XF; Tang, LB; Zhang, YX | 1 |
| Chang, KC; Chen, CH; Chiu, KW; Hu, TH; Hung, CH; Lee, CM; Lu, SN; Tsai, MC; Tseng, PL; Tung, WC; Wang, JH; Yen, YH | 1 |
| Abbott, WG; Hou, J; Huang, X; Jiang, X; Lai, Q; Li, Y; Ma, S; Sun, J; Zhang, M | 1 |
| Lau, GK; Wang, FS | 1 |
| Bai, XF; Li, Y; Lian, JQ; Nan, XP; Peng, MJ; Su, WJ; Sun, RL; Wang, JP; Yu, HT; Zhang, Y | 1 |
| Fontana, RJ; Singal, AK | 1 |
| Cao, MK; Han, GR; Jiang, HX; Pan, CQ; Wang, CM; Wang, GJ; Yue, X; Zhao, W | 1 |
| Fu, J; Gao, X; Li, L; Liu, M; Pan, X; Yao, W | 1 |
| Fan, XJ; Hu, XY; Liu, GW; Nie, HM; Zhang, Y; Zhong, S | 1 |
| Han, GR; Jiang, HX; Kan, NY; Wang, CM; Wang, GJ; Wu, MM; Yue, X | 1 |
| Cai, H; Da, Y; Jia, J; Lu, Y; Wang, M; Wu, L | 1 |
| Dusheiko, G | 1 |
| Jiang, S; Pan, HJ; Zheng, JL; Zhou, YJ | 1 |
| Chen, X; Huang, Z; Mao, Q; Ni, B; Tang, J; Tian, Y; Wang, Q; Wu, Y; Zhang, X; Zhang, Y; Zheng, Y; Zhou, J | 1 |
| Fan, R; Guo, Y; Hou, J; Li, X; Peng, J; Sun, J; Yang, S; Zhong, C | 1 |
| Almasio, PL; Bertino, G; Brandolino, N; Bruno, S; Caroleo, B; Cosco, L; Di Marco, V; Foti, G; Frugiuele, P; Galdieri, A; Madonia, S; Montalto, G; Portelli, V; Russello, M; Sapienza, M; Scifo, G; Siciliano, R; Spadaro, A; Stroffolini, T; Surace, L | 1 |
| Bai, L; Chen, EQ; Liang, LB; Tang, H; Wang, JR; Yan, LB; Zhou, TY | 1 |
| Huang, Y; Wang, J; Wang, M | 1 |
| Angelico, M; Demelia, L; di Paolo, D; Lenci, I; Nosotti, L; Piccolo, P; Sorbello, O | 1 |
| Jiang, H; Wang, J; Zhao, W | 1 |
| Chen, HZ; Deng, M; Gao, S; Ruan, B; Wang, B; Yang, SG; Zhou, X | 1 |
| Avila, C; Bao, W; Chan, HL; Chen, YC; Choudhuri, G; Chutaputti, A; Gane, EJ; Hwang, SG; Piratvisuth, T; Prabhakar, B; Safadi, R; Sarin, SK; Suh, DJ; Tanwandee, T; Trylesinski, A; Yurdaydin, C | 1 |
| Amato, G; Calise, F; Cuomo, O; Dicostanzo, G; Lanza, AG; Marcos, A; Perrella, A; Pisaniello, D; Santaniello, W | 1 |
| Fu, D; Huang, Y; Ma, Y; Shen, X; Wu, H; Wu, S | 1 |
| Baak, BC; Bakker, CM; Beuers, UH; Brouwer, JT; Buster, EH; Drenth, JP; Honkoop, P; Janssen, HL; Kerbert-Dreteler, MJ; Koek, GH; Tan, AC; van der Spek, BW; van Erpecum, KJ; van Hoek, B; van Nieuwkerk, KM; van Soest, H; Vrolijk, JM | 1 |
| Angeli, P; Cavallin, M; Fasolato, S; Gatta, A; Gola, E; Morando, F; Rosi, S | 1 |
| Su, QM; Ye, XG | 1 |
| Boglione, L; Cariti, G; D'Avolio, A; Di Perri, G | 1 |
| Jia, JD; Li, HY; Ma, H; Ren, JB; Sun, SJ; Wang, Y | 1 |
| Chen, Y; Liu, XX; Wang, LJ; Wu, YP; Xu, HX; Xu, YF; Yu, YX | 1 |
| Chang, TT; Chao, YC; Chen, YC; Hsu, CW; Lee, CM | 1 |
| Buti, M; Petersen, J | 1 |
| Cai, YJ; Feng, JY; Jiang, YF; Li, C; Ma, L; Niu, JQ; Wang, J; Yu, L | 1 |
| Amini-Bavil-Olyaee, S; Herbers, U; Luedde, T; Mueller, A; Tacke, F; Trautwein, C | 1 |
| Ardiri, AM; Bertino, G; Bertino, N; Calvagno, GS; Di Carlo, I; Malaguarnera, G; Malaguarnera, M; Ruggeri, MI; Toro, A | 1 |
| Baietto, L; Boglione, L; Burdino, E; Cariti, G; Cusato, J; D'Avolio, A; De Rosa, FG; Di Perri, G; Ghisetti, V; Gregori, G | 1 |
| Chen, R; Liu, SR; Tao, CJ; Zhang, SY | 1 |
| Bessone, F; Chan, HL; Cheinquer, H; Daruich, J; Dong, Y; Fassio, E; Komolmit, P; Ono, SK; Pathan, R; Pessôa, MG; Piratvisuth, T; Sukeepaisarnjaroen, W; Tanwandee, T; Trylesinski, A; Zeuzem, S | 1 |
| Chen, JJ; Chen, ZT; Gan, JH; Li, Y; Luo, EP; Wu, JC; Zhao, WF | 1 |
| Bai, XF; Huang, CX; Li, Y; Lian, JQ; Wang, JP; Zhang, Y | 1 |
| Jia, J | 1 |
| Jia, J; You, H | 1 |
| Ding, YP; Dong, YH; Wang, GQ | 1 |
| Chen, J; Ding, YP; Hou, FQ; Liu, YZ; Ren, YY; Song, G; Wang, GQ; Wang, Y; Wu, XJ; Yu, M | 1 |
| Chen, EQ; Liu, K; Lu, JJ; Ma, YJ; Tang, H; Wang, J | 1 |
| Bai, XF; Li, Y; Lian, JQ; Wang, JP; Zhang, Y | 1 |
| Deng, H; Gao, Z; Huang, Z; Lin, C; Peng, L; Zhao, Z; Zheng, Y | 1 |
| Chen, Y; Gao, Z; Han, Y; Han, Z; Jia, G; Li, C; Liu, J; Luo, G; Shi, Y; Xia, L; Yin, F; Zhou, X; Zhu, J | 1 |
| Cai, H; Liu, M; Yi, W | 1 |
| Chan, HL; Chan, HY; Cheung, CM; Lo, AO; Wong, GL; Wong, VW | 1 |
| Farnik, H; Herrmann, E; Hofmann, WP; Kronenberger, B; Peveling-Oberhag, J; Sarrazin, C; Susser, S; Zeuzem, S | 1 |
| Bao, W; Chan, HL; Gane, EJ; Hou, J; Jia, J; Liaw, YF; Naoumov, NV; Niu, J; Papatheodoridis, G; Thongsawat, S; Trylesinski, A; Wan, M; Wang, Y | 1 |
| Amarapurkar, DN; Patel, N | 1 |
| Liu, H; Wan, G; Wang, X; Yang, Z; Zeng, H | 1 |
| Huang, L; Li, J; Sun, J; Wu, M; Yan, J; Yan, Y; Zhang, X | 1 |
| Alteri, C; Andreoni, M; Angelico, M; Cento, V; De Sanctis, GM; Gubertini, G; Micheli, V; Parruti, G; Perno, CF; Pollicita, M; Romano, S; Salpini, R; Sarrecchia, C; Svicher, V; Visca, M | 1 |
| Ahn, SH; Han, KH; Kim, EH; Kim, SM; Lee, KH; Park, H | 1 |
| Bazzoli, F; Eusebi, LH; Festi, D; Lisotti, A; Mazzella, G | 1 |
| Hou, J; Liu, M; Lv, G; Sun, J; Wang, Y; Zheng, H; Zhou, B | 1 |
| Chang, KC; Chen, CH; Chiu, KW; Hu, TH; Hung, CH; Lee, CM; Lu, SN; Tsai, MC; Tseng, PL; Wang, JH; Yen, YH | 1 |
| Ayana, DA; Cai, Y; Ji, H; Jiang, Y; Li, C; Liu, M; Lv, P | 1 |
| Abbott, WG; Hou, J; Huang, X; Lai, Q; Li, CK; Li, Y; Ma, S; Naoumov, NV; Sun, J; Tang, L; Wang, W; Zhang, M; Zhang, Y | 1 |
| Fontana, RJ; Kuo, YF; Salameh, H; Singal, AK | 1 |
| Chan, HL; Chan, HY; Chim, AM; Lo, AO; Tse, CH; Wong, GL; Wong, VW | 1 |
| Bosheva, M; Ke, J; Praestgaard, J; Qi, Y; Stein, DS; Uy, G | 1 |
| Fan, HW; Fan, YM; Li, T; Liu, XQ; Liu, ZY; Lü, W; Mui, C; Ng, H; Yang, HH; Zhang, LF; Zhou, BT | 1 |
| Bose, PD; Das, BC; Goel, V; Gondal, R; Hazam, RK; Kar, P; Sarma, MP | 1 |
| Chen, H; Fan, C; Gong, Z; Wang, L | 1 |
| Chang, KC; Chiu, KW; Chou, YP; Hsu, YC; Hu, TH; Lin, MT; Tsai, MC; Tseng, PL; Yen, YH; Yu, HC | 1 |
| Cui, SN; Gong, YX; Guo, N; Wang, MM | 1 |
| Jang, JH; Kim, BJ; Lee, SW | 1 |
| Chang, MY; Chen, YC; Hsu, CW; Yeh, CT | 1 |
| Bonadies, G; Borgia, G; Borrelli, F; Buonomo, AR; Carleo, MA; Gentile, I; Portella, G | 1 |
| Hu, P; Huang, XY; Jin, JL; Lu, JH; Luo, SS; Weng, XH; Zhang, JM | 1 |
| Bai, X; Hao, C; Jia, Z; Kang, W; Lian, J; Ma, L; Peng, M; Wang, J; Xie, Y; Zhou, Y | 1 |
| Hsu, PI; Lai, KH; Lin, KH; Tsai, TJ; Tsay, FW; Wang, HM; Yu, HC | 1 |
| Bosset, S; Buti, M; Deray, G; Di Bisceglie, A; Gane, EJ; Lai, CL; Liaw, YF; Lim, SG; Papatheodoridis, G; Rasenack, J; Samuel, D; Trylesinski, A; Uddin, A; Wang, Y | 1 |
| Mao, Q; Ni, B; Ni, D; Song, J; Tian, Y; Tian, Z; van Velkinburgh, JC; Wu, Y; Yang, D; Yang, W; Zhang, Y; Zhao, K | 1 |
| Guo, SH; Sandeep, KK; Zhang, DZ; Zhang, QF; Zhang, W | 1 |
| Feng, Q; Hu, HD; Hu, P; Liu, Q; Ren, H; Sun, H; Wang, N | 1 |
| Lok, AS; Yapali, S | 1 |
| Cholongitas, E; Papatheodoridis, G; Pipili, C | 1 |
| Chen, DB; Chen, YM; Gao, ZL; Huang, ZL; Liu, J; Lu, CR; Xie, DY; Zhu, RH | 1 |
| Lao, XM; Li, SP; Lin, XJ; Xia, HH | 1 |
| Ahn, SH; Hahn, KY; Han, KH; Kim, BK; Kim, DY; Kim, HC; Kim, JK; Kim, SU; Park, JY; Park, YH; Shin, SH | 1 |
| Kim, HY; Kim, YJ; Lee, HJ; Lee, HS; Lee, JH; Lee, M; Oh, S; Yeum, TS; Yoon, JH; Yu, SJ | 1 |
| Deng, YR; Jin, QL; Lian, ZX; Matsuzaki, K; Moritoki, Y; Murata, M; Niu, JQ; Tsuneyama, K; Yamaguchi, T; Yoshida, K | 1 |
| Fung, J; Lai, CL; Seto, WK; Yuen, MF | 1 |
| Calvaruso, V; Craxì, A | 1 |
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| Bai, X; Chen, C; Chen, S; Chen, X; Cheng, J; Dou, X; Fan, R; Gao, Z; Hou, J; Jia, J; Ma, H; Ning, Q; Niu, J; Ren, H; Sheng, J; Shi, G; Shi, J; Sun, J; Tan, D; Tang, H; Wan, M; Wang, H; Wang, M; Xie, Q; Xu, M; Yu, Y; Zhang, H | 1 |
| Ahn, SH; Chon, CY; Han, KH; Kim, DY; Kim, SU; Park, H; Park, JY | 1 |
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| Abbott, WG; Ge, J; Hou, J; Huang, X; Huang, Z; Jiang, X; Lai, Q; Li, Y; Ma, S; Sun, J; Zhang, M; Zhang, X | 1 |
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| Gao, X; Liu, P; Lu, XD; Lu, YQ; Meng, N; Tang, WX; Wang, M; Yan, W; Zhang, SJ | 1 |
| Chen, L; Huang, Y; Mao, R; Qi, X; Qin, Y; Wang, J; Zhang, J | 1 |
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| Bao, W; Chen, C; Dong, Y; Goodman, Z; Hou, JL; Jia, J; Naoumov, NV; Niu, J; Ren, H; Shi, G; Tan, D; Trylesinski, A; Wan, M; Wang, Q; Wang, Y; Wei, L; Xie, Q; Xu, D | 1 |
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| Arenas, J; Blázquez, A; Delmiro, A; Domínguez-González, C; Fernández-Vázquez, I; Guerrero, AM; Hernández-Laín, A; Martín, MA; Maya, DG; Morales, JR; Moran, M | 1 |
| Krishnamoorthy, TL; Mutimer, D | 1 |
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| Chen, Y; Dong, H; Fan, R; He, Y; Hou, J; Huang, X; Jia, J; Jin, L; Jin, W; Li, R; Locarnini, S; Lu, F; Shen, Y; Sun, J; Wang, M; Wang, S; Xie, Q; Xie, S; Zhao, GP; Zhou, B; Zhuang, H | 1 |
| Kittitrakul, C; Leowattana, W; Nontprasert, A; Phumratanaprapin, W; Poovorawan, K; Sriboonvorakul, N; Tangkijvanich, P; Thu, AM; Wilairatana, P | 1 |
| Cao, ZH; Chen, XY; He, ZM; Jin, Y; Liu, YL; Lu, JF; Ma, LN; Zhang, SB | 1 |
| Bair, MJ; Chang, CW; Chen, CJ; Chen, MJ; Chu, CH; Hu, KC; Lee, KH; Lin, CC; Lin, SC; Liou, TC; Liu, CY; Shih, SC; Wang, HY; Wang, TE | 1 |
| Fung, J; Lai, CL; Wong, DK; Yuen, MF | 1 |
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| Andini, R; Durante-Mangoni, E; Falco, E; Iossa, D; Maiello, C; Parrella, A; Ragone, E; Utili, R; Vitrone, M; Zampino, R | 1 |
| Liu, Y; Qiu, P; Wang, GL; Wen, JB; Wen, P; Xiao, XZ; Xu, LF; Zhou, SF | 1 |
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| Chen, FY; Cheng, Z; Huang, HH; Shi, KQ; Zhang, MY; Zheng, JN; Zheng, MH; Zhu, GQ; Zou, ZL | 1 |
| Chan, HL; Gupta, S; Hamed, K; Shaikh, J | 1 |
| Cao, F; Chen, T; Feng, W; Guo, D; Jin, D; Jin, L; Liu, J; Qi, C; Tian, Z; Wang, J; Yan, T; Yuan, N; Zhang, S; Zhao, Y | 1 |
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| Gao, Y; Ke, W; Liu, L; Yang, Y; Yao, Z; Ye, X; Zhang, C; Zhou, S | 1 |
| Dai, YP; Fu, DC; Guo, XY; Hua, Z; Li, YG; Tu, KW; Xu, W | 1 |
| Chang, CY; Chen, TB; Hsu, YC; Lin, JT; Mo, LR; Tseng, CM | 1 |
| Chen, R; Chen, XF; Chen, XP; Huang, J; Luo, XD | 1 |
| Bai, H; Ding, Y; Dou, XG; Fan, YX; Han, C; Li, BJ; Li, YW; Sheng, QJ; Zhang, C | 1 |
| Chen, Y; Cheng, KL; Duan, XW; Duan, ZP; Li, Y; Qiu, Q; Wang, L; Xu, MM; Yang, LK | 1 |
| Dong, H; He, Y; Hou, J; Jin, W; Kang, H; Shen, Y; Sun, J; Wang, S; Zhao, G; Zhou, B; Zhu, Y | 1 |
| Ambang, T; Goh, KJ; Ong, S; Tan, JS; Wong, KT | 1 |
| Cheng, C; Chong, CK; Cullaro, G; Fung, J; Huang, FY; Ip, P; Kopaniszen, M; Lai, CL; Lee, B; Ngai, V; Seto, WK; Wong, D; Wu, R; Yuen, J; Yuen, MF | 1 |
| Chen, CH; Hu, TH; Hung, CH; Lee, CM; Lu, SN; Tsai, MC; Wang, JH | 1 |
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93 review(s) available for thymidine and telbivudine
| Article | Year |
|---|---|
Telbivudine/Torcitabine Idenix/Novartis.
Topics: Animals; Antiviral Agents; Clinical Trials as Topic; Drugs, Investigational; Hepatitis B; Hepatitis B virus; Humans; Nucleosides; Pyrimidinones; Technology, Pharmaceutical; Telbivudine; Thymidine | 2004 |
New treatment of chronic hepatitis B.
Topics: Adenine; Animals; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Organophosphorus Compounds; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2004 |
Telbivudine: a new nucleoside analogue for the treatment of chronic hepatitis B.
Topics: Animals; Antiviral Agents; Disease Models, Animal; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Pyrimidinones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine | 2005 |
Telbivudine: an upcoming agent for chronic hepatitis B.
Topics: Antiviral Agents; DNA, Viral; Hepatitis B virus; Hepatitis B, Chronic; Humans; Molecular Structure; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2005 |
Telbivudine: a novel nucleoside analog for chronic hepatitis B.
Topics: Animals; Antiviral Agents; Clinical Trials as Topic; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2006 |
Novel anti-hepatitis B agents: A focus on telbivudine.
Topics: Antiviral Agents; Clinical Trials, Phase II as Topic; DNA, Viral; Drug Resistance, Viral; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Viral Core Proteins | 2006 |
[Progress in the treatment of chronic hepatitis B with Telbivudine].
Topics: Antiviral Agents; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2006 |
Improving outcomes for patients with chronic hepatitis B.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B Vaccines; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Telbivudine; Thymidine; Treatment Outcome; Viral Load | 2007 |
Telbivudine: a new option for the treatment of chronic hepatitis B.
Topics: Animals; Antiviral Agents; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome | 2007 |
Treatment paradigms on hepatitis B e antigen-negative chronic hepatitis B patients.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Thymidine | 2007 |
Treatment of chronic hepatitis B in HIV-infected patients in 2007.
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B, Chronic; HIV Infections; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2007 |
Telbivudine.
Topics: Antiviral Agents; Hepatitis B virus; Hepatitis B, Chronic; Humans; Nucleic Acid Synthesis Inhibitors; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2007 |
Telbivudine for the treatment of chronic hepatitis B.
Topics: Antiviral Agents; Clinical Trials as Topic; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Virus Replication | 2007 |
Therapy of chronic hepatitis B: focus on telbivudine.
Topics: Alanine Transaminase; Antiviral Agents; DNA, Viral; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Randomized Controlled Trials as Topic; Telbivudine; Thymidine; Viral Load | 2007 |
Telbivudine: a new treatment for chronic hepatitis B.
Topics: Antiviral Agents; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Hepatitis B, Chronic; Humans; India; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2007 |
Telbivudine for the management of chronic hepatitis B virus infection.
Topics: Alanine Transaminase; Antiviral Agents; Clinical Trials as Topic; DNA, Viral; Drug Interactions; Drug Resistance, Viral; Hepatitis B, Chronic; Humans; Molecular Structure; Nucleosides; Pyrimidinones; Salvage Therapy; Telbivudine; Thymidine | 2007 |
Active antiviral therapy for chronic hepatitis B and hepatocellular carcinoma.
Topics: Antiviral Agents; Carcinoma, Hepatocellular; Hepatitis B, Chronic; Humans; Interferons; Lamivudine; Liver Neoplasms; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2008 |
[Pharmacological agents for the treatment of chronic hepatitis B].
Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Drug Therapy, Combination; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine; Time Factors; Treatment Outcome | 2008 |
Clinical implications of resistance patterns against HBV-polymerase inhibitors for the treatment of chronic hepatitis B.
Topics: Adenine; Drug Resistance, Viral; Drug Therapy, Combination; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine | 2007 |
[Telbivudine in the treatment of the chronic B hepatitis].
Topics: Adolescent; Adult; Aged; Antiviral Agents; Biomarkers, Pharmacological; Biotransformation; Clinical Trials, Phase III as Topic; Drug Resistance, Viral; Female; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Muscular Diseases; Nucleosides; Phosphorylation; Prodrugs; Pyrimidinones; Randomized Controlled Trials as Topic; Telbivudine; Thymidine; Virus Replication | 2008 |
Review article: current antiviral therapy of chronic hepatitis B.
Topics: Adenine; Antiviral Agents; Carcinoma, Hepatocellular; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Cirrhosis; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Virus Replication | 2008 |
What's new in clinical pharmacology and therapeutics.
Topics: Abatacept; Acetanilides; Amides; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antiparkinson Agents; Antirheumatic Agents; Antiviral Agents; Apomorphine; Benzazepines; Cardiovascular Agents; Fumarates; Hepatitis B; Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18; Humans; Hypoglycemic Agents; Immunoconjugates; Multiple Sclerosis; Natalizumab; Nucleosides; Papillomavirus Vaccines; Pharmacology, Clinical; Piperazines; Pyrazines; Pyrimidinones; Quinoxalines; Ranolazine; Sitagliptin Phosphate; Smoking Cessation; Telbivudine; Thymidine; Triazoles; Varenicline; Viral Vaccines | 2008 |
[Management of antiviral-resistant chronic hepatitis B virus infection].
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Drug Resistance, Multiple, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Mutation; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome | 2008 |
A review of telbivudine for the management of chronic hepatitis B virus infection.
Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Drug Evaluation, Preclinical; Drug Resistance, Viral; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Thymidine | 2008 |
Hepatitis B and liver transplantation: 2008 update.
Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Guanine; Hepatitis B; Hepatitis B Vaccines; Humans; Immunoglobulins; Lamivudine; Liver Transplantation; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2009 |
Telbivudine in the treatment of chronic hepatitis B.
Topics: Drug Resistance, Viral; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2008 |
[Interferon in hepatitis B].
Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Drug Therapy, Combination; Genotype; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Multicenter Studies as Topic; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Randomized Controlled Trials as Topic; Recombinant Proteins; Telbivudine; Thymidine; Treatment Outcome | 2008 |
[Nucleoside and nucleotide analogs in the treatment of chronic hepatitis B].
Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Multicenter Studies as Topic; Nucleosides; Organophosphonates; Pyrimidinones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Treatment Outcome; Virus Replication | 2008 |
[Clinical management of patients with chronic hepatitis B virus infection].
Topics: Adenine; Antiviral Agents; Biopsy; Combined Modality Therapy; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Female; Genotype; Guanine; Hepatitis B Antibodies; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Liver; Liver Transplantation; Male; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Virus Replication | 2008 |
[Hepatitis B in patients with HIV infection].
Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; Comorbidity; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B; Hepatitis B Vaccines; Hepatitis B virus; HIV; HIV Infections; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Virus Replication | 2008 |
Nucleos(t)ide analogues for hepatitis B virus: strategies for long-term success.
Topics: Adenine; Adenine Nucleotides; Alanine Transaminase; Carcinoma, Hepatocellular; DNA, Viral; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Nucleosides; Organophosphonates; Pyrimidinones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine; Treatment Outcome; Virus Replication | 2008 |
Peginterferon for the treatment of chronic hepatitis B in the era of nucleos(t)ide analogues.
Topics: Adenine; Antiviral Agents; DNA, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Polyethylene Glycols; Practice Guidelines as Topic; Pyrimidinones; Randomized Controlled Trials as Topic; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2008 |
HBeAg-negative chronic hepatitis B: why do I treat my patients with nucleos(t)ide analogues.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Virus Replication | 2009 |
Telbivudine in the treatment of chronic hepatitis B.
Topics: Alanine Transaminase; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; DNA, Viral; Drug Evaluation, Preclinical; Drug Interactions; Drug Resistance, Viral; Hepatitis B virus; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Safety; Telbivudine; Thymidine; Treatment Outcome; Virus Replication | 2009 |
Chronic hepatitis B: early viral suppression and long-term outcomes of therapy with oral nucleos(t)ides.
Topics: Adenine; Administration, Oral; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine; Time Factors; Treatment Outcome | 2009 |
On-treatment outcome prediction and adjustment during chronic hepatitis B therapy: now and future.
Topics: Adenine; Antiviral Agents; Cost-Benefit Analysis; DNA, Viral; Drug Resistance, Multiple, Viral; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Medication Adherence; Nucleosides; Organophosphonates; Polyethylene Glycols; Prognosis; Pyrimidinones; Recombinant Proteins; Telbivudine; Thymidine; Time Factors; Treatment Outcome | 2009 |
Treatment of chronic hepatitis B: focus on telbivudine.
Topics: Antiviral Agents; Clinical Trials as Topic; Drug Resistance, Viral; Hepatitis B virus; Hepatitis B, Chronic; Humans; Nucleic Acid Synthesis Inhibitors; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Virus Replication | 2009 |
Myopathy and neuropathy associated with nucleos(t)ide analog therapy for hepatitis B.
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Creatine Kinase; Drug Discovery; Early Termination of Clinical Trials; Hepatitis B, Chronic; Humans; Lamivudine; Mitochondrial Myopathies; Muscular Diseases; Nervous System Diseases; Nucleosides; Nucleotides; Pyrimidinones; Republic of Korea; Telbivudine; Thymidine | 2009 |
Telbivudine for the treatment of chronic hepatitis B infection.
Topics: Adult; Antiviral Agents; Cost-Benefit Analysis; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2009 |
Current status of nucleoside antivirals in chronic hepatitis B.
Topics: Antiviral Agents; Cost-Benefit Analysis; Drug Resistance, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2009 |
Effect of newer oral antiviral agents on future therapy of chronic hepatitis B.
Topics: Adenine; Administration, Oral; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2010 |
On-treatment monitoring of chronic hepatitis B virus infection: an Asian-Pacific perspective.
Topics: Adenine; Antiviral Agents; Asia; Biomarkers; DNA, Viral; Drug Monitoring; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Time Factors; Treatment Outcome; Viral Load; Virus Replication | 2010 |
Safety evaluation of telbivudine.
Topics: Adult; Antiviral Agents; Biomarkers; Creatine Kinase; Double-Blind Method; Drug Resistance, Viral; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Isoenzymes; Male; Multicenter Studies as Topic; Muscular Diseases; Nucleosides; Peripheral Nervous System Diseases; Predictive Value of Tests; Pregnancy; Pregnancy Complications, Infectious; Pyrimidinones; Randomized Controlled Trials as Topic; Telbivudine; Thymidine | 2010 |
Telbivudine: an effective anti-HBV drug for chronic hepatitis B patients with early on-treatment responses.
Topics: Antiviral Agents; Clinical Trials as Topic; Drug Resistance, Viral; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Time Factors; Treatment Outcome | 2010 |
Comparison of the efficacy of lamivudine and telbivudine in the treatment of chronic hepatitis B: a systematic review.
Topics: Antiviral Agents; Clinical Trials as Topic; Databases, Factual; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome | 2010 |
Telbivudine: a review of its use in compensated chronic hepatitis B.
Topics: Antiviral Agents; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2010 |
Treatment of HBeAg-positive chronic hepatitis B with nucleos(t)ide analogues.
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2011 |
Hepatitis B virus resistance to antiviral drugs: where are we going?
Topics: Adenine; Antiviral Agents; Capsid; Clinical Protocols; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Virus Internalization; Virus Replication | 2011 |
The impact of human immunodeficiency virus on viral hepatitis.
Topics: Adenine; Antiviral Agents; Deoxycytidine; Disease Progression; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B; Hepatitis C; Hepatitis Viruses; HIV Infections; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2011 |
[Interferon-based versus direct antiviral therapy in patients with chronic hepatitis B].
Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Nucleotides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2011 |
Antiviral therapy for hepatitis B infection during pregnancy and breastfeeding.
Topics: Adenine; Antiviral Agents; Breast Feeding; Female; Guanine; Hepatitis B; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Placenta; Pregnancy; Pregnancy Complications, Infectious; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2011 |
Antiviral drugs for viruses other than human immunodeficiency virus.
Topics: Acyclovir; Adenine; Amantadine; Antiviral Agents; Comorbidity; Drug Therapy, Combination; Foscarnet; Ganciclovir; Guanine; Hepatitis; Hepatitis B, Chronic; Hepatitis C; Herpesviridae Infections; HIV Infections; Humans; Influenza, Human; Interferons; Lamivudine; Nucleosides; Oligopeptides; Organophosphonates; Oseltamivir; Proline; Protease Inhibitors; Pyrimidinones; Ribavirin; Telbivudine; Thymidine; Valacyclovir; Valganciclovir; Valine; Virus Replication; Zanamivir | 2011 |
[Pharmacological treatment of acute hepatitis B].
Topics: Acute Disease; Adenine; Antiviral Agents; Guanine; Hepatitis B; Humans; Lamivudine; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pyrimidinones; Spain; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2012 |
Meta-analysis: oral anti-viral agents in adults with decompensated hepatitis B virus cirrhosis.
Topics: Adenine; Administration, Oral; Adult; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Nucleosides; Organophosphonates; Pyrimidinones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Time Factors; Treatment Outcome; Viral Load | 2012 |
[New drugs of treatment of patients with chronic hepatitis B].
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Emtricitabine; Hepatitis B, Chronic; Humans; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2012 |
Lamivudine versus telbivudine in the treatment of chronic hepatitis B: a systematic review and meta-analysis.
Topics: Antiviral Agents; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Liver Function Tests; Randomized Controlled Trials as Topic; Telbivudine; Thymidine; Time Factors; Treatment Outcome; Viral Load | 2013 |
The effects of telbivudine in late pregnancy to prevent intrauterine transmission of the hepatitis B virus: a systematic review and meta-analysis.
Topics: Antiviral Agents; Female; Hepatitis B Antibodies; Hepatitis B, Chronic; Humans; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; Telbivudine; Thymidine; Treatment Outcome | 2012 |
A meta-analysis of nucleos(t)ide analogues in patients with decompensated cirrhosis due to hepatitis B.
Topics: Antiviral Agents; Hepatitis B; Humans; Lamivudine; Liver Cirrhosis; Nucleosides; Nucleotides; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine | 2013 |
Effects of telbivudine and entecavir for HBeAg-positive chronic hepatitis B: a meta-analysis.
Topics: Adult; Antiviral Agents; Biomarkers; Chi-Square Distribution; Drug Resistance, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Middle Aged; Telbivudine; Thymidine; Time Factors; Treatment Outcome; Young Adult | 2012 |
[Efficacy and safety of telbivudine treatment to block mother-to-child transmission of hepatitis B virus: a meta-analysis].
Topics: Antiviral Agents; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Infant; Infectious Disease Transmission, Vertical; Mothers; Pregnancy; Pregnancy Complications, Infectious; Randomized Controlled Trials as Topic; Telbivudine; Thymidine | 2012 |
Considerations for the long-term treatment of chronic hepatitis B with nucleos(t)ide analogs.
Topics: Adenine; Age Factors; Antiviral Agents; Comorbidity; DNA, Viral; Drug Resistance, Viral; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Life Style; Organophosphonates; Severity of Illness Index; Telbivudine; Tenofovir; Thymidine; Time Factors | 2012 |
Telbivudine on-treatment HBsAg loss in naive HBeAg negative chronic hepatitis B: a case report and brief review of the literature.
Topics: Antiviral Agents; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Telbivudine; Thymidine | 2012 |
Telbivudine treatment in chronic hepatitis B: experience from China.
Topics: Antiviral Agents; China; Clinical Trials as Topic; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; Telbivudine; Thymidine; Treatment Outcome | 2013 |
Telbivudine treatment is associated with high hepatitis B e antigen seroconversion and immune modulatory effects in chronic hepatitis B patients.
Topics: Antiviral Agents; China; Clinical Trials as Topic; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Immunomodulation; Telbivudine; Thymidine; Treatment Outcome | 2013 |
Telbivudine versus entecavir for nucleos(t)ide-naive HBeAg-positive chronic hepatitis B: a meta-analysis.
Topics: Antiviral Agents; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Telbivudine; Thymidine | 2014 |
Meta-analysis: the impact of oral anti-viral agents on the incidence of hepatocellular carcinoma in chronic hepatitis B.
Topics: Adenine; Administration, Oral; Age Factors; Antiviral Agents; Carcinoma, Hepatocellular; Guanine; Hepatitis B, Chronic; Humans; Incidence; Liver Neoplasms; Organophosphonates; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2013 |
Lactic acidosis during telbivudine treatment for HBV: a case report and literature review.
Topics: Acidosis, Lactic; Adult; Antiviral Agents; Hepatitis B, Chronic; Humans; Male; Mitochondrial Diseases; Muscular Diseases; Telbivudine; Thymidine | 2013 |
Comparison of the forty-eight week efficacy between telbivudine and entecavir in HBeAg-positive Asian patients with chronic hepatitis B: A meta-analysis.
Topics: Alanine Transaminase; Antiviral Agents; Asian People; Creatine Kinase; DNA, Viral; Drug Resistance, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Telbivudine; Thymidine; Time Factors | 2013 |
Review article: nucleos(t)ide analogues in patients with chronic hepatitis B virus infection and chronic kidney disease.
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Renal Insufficiency, Chronic; Telbivudine; Tenofovir; Thymidine | 2014 |
Extrahepatic effects of nucleoside and nucleotide analogues in chronic hepatitis B treatment.
Topics: Acidosis, Lactic; Adenine; Administration, Oral; Antiviral Agents; Arabinofuranosyluracil; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hepatitis B, Chronic; Humans; Kidney Diseases; Male; Muscular Diseases; Nervous System Diseases; Nucleosides; Nucleotides; Organophosphonates; Pharmacovigilance; Pregnancy; Telbivudine; Tenofovir; Thymidine | 2014 |
Regression of fibrosis after HBV antiviral therapy. Is cirrhosis reversible?
Topics: Adenine; Administration, Oral; Antiviral Agents; Carcinoma, Hepatocellular; Fibrosis; Guanine; Hepatitis B; Hepatitis B virus; Humans; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Nucleosides; Organophosphonates; Telbivudine; Tenofovir; Thymidine | 2014 |
HBeAg-positive chronic hepatitis B: why do i treat my patients with Nucleos(t)ide analogs?
Topics: Adenine; Age Factors; Antiviral Agents; Biomarkers; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Polyethylene Glycols; Precision Medicine; Recombinant Proteins; Sex Factors; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2014 |
New therapeutic perspectives in HBV: when to stop NAs.
Topics: Adenine; Algorithms; Antiviral Agents; Biomarkers; DNA, Viral; Drug Therapy, Combination; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine | 2014 |
Telbivudine during the second and third trimester of pregnancy interrupts HBV intrauterine transmission: a systematic review and meta-analysis.
Topics: Antiviral Agents; Female; Hepatitis B; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Telbivudine; Thymidine | 2014 |
Continuous venovenous hemodiafiltration for hyperlactatemia caused by telbivudine in a patient with chronic hepatitis B: a case report and update review.
Topics: Adult; Antiviral Agents; Biomarkers; Creatine Kinase; Hemodiafiltration; Hepatitis B, Chronic; Humans; Hyperlactatemia; Male; Myalgia; Telbivudine; Thymidine | 2015 |
Hepatitis B and C in pregnancy: a review and recommendations for care.
Topics: Antiviral Agents; Breast Feeding; Cesarean Section; Contraindications; DNA, Viral; Female; Hepatitis B virus; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Mass Screening; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Telbivudine; Thymidine; Viremia | 2014 |
Changes in serum alanine aminotransferase levels in telbivudine versus lamivudine treatment for chronic hepatitis B: a meta-analysis.
Topics: Alanine Transaminase; Antiviral Agents; Biomarkers; Hepatitis B, Chronic; Humans; Lamivudine; Telbivudine; Thymidine; Treatment Outcome | 2015 |
How to achieve immune control in chronic hepatitis B?
Topics: Antiviral Agents; Biomarkers; DNA, Circular; DNA, Viral; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunomodulation; Interferon-alpha; Interleukins; Lamivudine; Polyethylene Glycols; Pteridines; Telbivudine; Thymidine | 2015 |
Comparative efficacy of antiviral therapy in preventing vertical transmission of hepatitis B: a network meta-analysis.
Topics: Antiviral Agents; Female; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Network Meta-Analysis; Pregnancy; Pregnancy Complications, Infectious; Randomized Controlled Trials as Topic; Telbivudine; Thymidine; Viral Load | 2016 |
Hepatitis B: encouraging the use of interferon.
Topics: Adjuvants, Immunologic; Antiviral Agents; Carcinoma, Hepatocellular; Contraindications; Drug Administration Schedule; Drug Therapy, Combination; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Liver Cirrhosis; Liver Neoplasms; Telbivudine; Thymidine | 2015 |
Monotherapy for hepatitis B infection: a review of treatment options.
Topics: Adenine; Animals; Antiviral Agents; Carcinoma, Hepatocellular; Guanine; Hepatitis B, Chronic; Humans; Interferons; Lamivudine; Liver Neoplasms; Organophosphonates; Telbivudine; Thymidine; Treatment Outcome | 2015 |
Effect of Telbivudine Versus Other Nucleos(t)ide Analogs on HBeAg Seroconversion and Other Outcomes in Patients with Chronic Hepatitis B: A Network Meta-Analysis.
Topics: Antiviral Agents; Comparative Effectiveness Research; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Nucleic Acid Synthesis Inhibitors; Randomized Controlled Trials as Topic; Seroconversion; Telbivudine; Thymidine; Time; Treatment Outcome | 2016 |
Potential effects of telbivudine and entecavir on renal function: a systematic review and meta-analysis.
Topics: Antiviral Agents; China; Guanine; Hepatitis B, Chronic; Humans; Kidney; Kidney Diseases; Kidney Function Tests; Telbivudine; Thymidine | 2016 |
Systematic review with network meta-analysis: Comparative efficacy of oral nucleos(t)ide analogues for the prevention of chemotherapy-induced hepatitis B virus reactivation.
Topics: Adenine; Antineoplastic Agents; Antiviral Agents; Controlled Clinical Trials as Topic; Guanine; Hepatitis B; Hepatitis B virus; Host-Pathogen Interactions; Humans; Lamivudine; Organophosphonates; Telbivudine; Thymidine; Virus Activation | 2016 |
Renal Function in Nucleos(t)ide Analog-Treated Patients With Chronic Hepatitis B: A Systematic Literature Review and Network Meta-Analysis.
Topics: Antiviral Agents; Glomerular Filtration Rate; Hepatitis B, Chronic; Humans; Kidney; Protective Agents; Telbivudine; Thymidine | 2016 |
Chronic hepatitis B in children: Therapeutic challenges and perspectives.
Topics: Adenine; Alanine Transaminase; Antigens, Viral; Antiviral Agents; Child; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immune Tolerance; Interferon-alpha; Lamivudine; Molecular Targeted Therapy; Organophosphonates; Practice Guidelines as Topic; Seroconversion; Telbivudine; Tenofovir; Thymidine; Viral Envelope Proteins | 2017 |
HBeAg Seroconversion in HBeAg-Positive Chronic Hepatitis B Patients Receiving Long-Term Nucleos(t)ide Analog Treatment: A Systematic Review and Network Meta-Analysis.
Topics: Antiviral Agents; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Telbivudine; Thymidine | 2017 |
Nucleos(t)ide analogues for preventing HBV reactivation in immunosuppressed patients with hematological malignancies: a network meta-analysis.
Topics: Adenine; Antiviral Agents; Controlled Clinical Trials as Topic; Guanine; Hematologic Neoplasms; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunocompromised Host; Lamivudine; Organophosphonates; Survival Analysis; Telbivudine; Tenofovir; Thymidine; Treatment Outcome; Virus Activation | 2017 |
Efficacy of Nucleot(s)ide Analogs Therapy in Patients with Unresectable HBV-Related Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis.
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Carcinoma, Hepatocellular; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Neoplasms; Organophosphonates; Retrospective Studies; Survival Analysis; Telbivudine; Tenofovir; Thymidine | 2017 |
Hepatitis B During Pregnancy in Endemic Areas: Screening, Treatment, and Prevention of Mother-to-Child Transmission.
Topics: Antiviral Agents; Endemic Diseases; Female; Hepatitis B Vaccines; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunization; Immunoglobulins; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; Telbivudine; Tenofovir; Thymidine; Viral Load | 2017 |
Combination Therapy for Chronic Hepatitis B: Current Updates and Perspectives.
Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Telbivudine; Tenofovir; Thymidine; Treatment Outcome; Viral Load | 2017 |
Telbivudine therapy for gravidas with chronic hepatitis B infection and patients at risk of renal impairment.
Topics: Animals; Antiviral Agents; Female; Hepatitis B, Chronic; Humans; Pregnancy; Pregnancy Complications, Infectious; Renal Insufficiency; Risk; Telbivudine; Thymidine; Treatment Outcome; Viral Load | 2017 |
Rhabdomyolysis, lactic acidosis, and multiple organ failure during telbivudine treatment for hepatitis B: a case report and review of the literature.
Topics: Acidosis, Lactic; Adult; Antiviral Agents; Asian People; Hepatitis B, Chronic; Humans; Male; Multiple Organ Failure; Physical Therapy Modalities; Renal Replacement Therapy; Rhabdomyolysis; Telbivudine; Thymidine; Treatment Outcome | 2017 |
78 trial(s) available for thymidine and telbivudine
| Article | Year |
|---|---|
A dose-finding study of once-daily oral telbivudine in HBeAg-positive patients with chronic hepatitis B virus infection.
Topics: Adult; Aged; DNA, Viral; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2004 |
A 1-year trial of telbivudine, lamivudine, and the combination in patients with hepatitis B e antigen-positive chronic hepatitis B.
Topics: Adolescent; Adult; Age Factors; Aged; DNA, Viral; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Liver Function Tests; Long-Term Care; Male; Maximum Tolerated Dose; Middle Aged; Nucleosides; Pyrimidinones; Reference Values; Risk Assessment; Severity of Illness Index; Sex Factors; Telbivudine; Thymidine; Treatment Outcome | 2005 |
Absence of food effect on the pharmacokinetics of telbivudine following oral administration in healthy subjects.
Topics: Absorption; Administration, Oral; Adult; Antiviral Agents; Area Under Curve; Cross-Over Studies; Dietary Fats; Drug Monitoring; Energy Intake; Fasting; Female; Food; Food-Drug Interactions; Humans; Male; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2006 |
Pharmacokinetics of telbivudine following oral administration of escalating single and multiple doses in patients with chronic hepatitis B virus infection: pharmacodynamic implications.
Topics: Administration, Oral; Adult; Antiviral Agents; Area Under Curve; Asian People; China; Cohort Studies; DNA, Viral; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Half-Life; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Time Factors; Treatment Outcome | 2006 |
Pharmacokinetics of telbivudine in subjects with various degrees of hepatic impairment.
Topics: Administration, Oral; Antiviral Agents; Area Under Curve; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Humans; Liver Diseases; Male; Mass Spectrometry; Middle Aged; Nucleosides; Pyrimidinones; Severity of Illness Index; Telbivudine; Thymidine | 2006 |
Pharmacokinetics of telbivudine in healthy subjects and absence of drug interaction with lamivudine or adefovir dipivoxil.
Topics: Adenine; Administration, Oral; Adult; Anti-HIV Agents; Antiviral Agents; Area Under Curve; Drug Interactions; Drug Therapy, Combination; Female; Humans; Lamivudine; Male; Middle Aged; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine | 2006 |
Single-dose and multiple-dose pharmacokinetics and safety of telbivudine after oral administration in healthy Chinese subjects.
Topics: Administration, Oral; Adult; China; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Female; Health; Humans; Male; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2006 |
[Study on the pharmacokinetic profile of telbivudine].
Topics: Adolescent; Adult; Dose-Response Relationship, Drug; Female; Humans; Male; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Young Adult | 2006 |
[The degree of HBV suppression with 24 week telbivudine- or lamivudine-treatment in hepatitis B patients predicts the efficacy of the treatment at week 52].
Topics: Adolescent; Adult; Aged; Antiviral Agents; DNA, Viral; Double-Blind Method; Female; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2007 |
Pharmacokinetics of telbivudine in subjects with various degrees of renal impairment.
Topics: Adolescent; Adult; Aged; Female; Humans; Kidney Diseases; Kidney Failure, Chronic; Kidney Function Tests; Male; Metabolic Clearance Rate; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2007 |
Treatment of hepatitis B e antigen positive chronic hepatitis with telbivudine or adefovir: a randomized trial.
Topics: Adenine; Adolescent; Adult; Aged; Antiviral Agents; Biomarkers; DNA, Viral; Drug Therapy, Combination; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Thymidine; Viral Load | 2007 |
Telbivudine versus lamivudine in Chinese patients with chronic hepatitis B: Results at 1 year of a randomized, double-blind trial.
Topics: Adolescent; Adult; Antiviral Agents; China; DNA, Viral; Double-Blind Method; Female; Genotype; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2008 |
Telbivudine versus lamivudine in patients with chronic hepatitis B.
Topics: Adolescent; Adult; Aged; Antiviral Agents; DNA, Viral; Double-Blind Method; Drug Resistance, Viral; Female; Genotype; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2007 |
[The efficacy and safety of telbivudine in korean patients with chronic hepatitis B].
Topics: Adolescent; Adult; Alanine Transaminase; Antiviral Agents; Drug Resistance, Viral; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Korea; Lamivudine; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome | 2007 |
[Short-term results of telbivudine versus entecavir treatments in HBeAg-positive chronic hepatitis B patients in China].
Topics: Adolescent; Adult; Aged; Antiviral Agents; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Viral Load; Young Adult | 2008 |
2-Year GLOBE trial results: telbivudine Is superior to lamivudine in patients with chronic hepatitis B.
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Double-Blind Method; Female; Global Health; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Longitudinal Studies; Male; Middle Aged; Nucleosides; Prospective Studies; Pyrimidinones; Regression Analysis; Telbivudine; Thymidine; Treatment Outcome; Virus Replication; Young Adult | 2009 |
[Telbivudine treatment on cirrhosis resulting from chronic hepatitis B].
Topics: Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome; Virus Replication | 2009 |
Baseline characteristics and early on-treatment response predict the outcomes of 2 years of telbivudine treatment of chronic hepatitis B.
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome | 2009 |
[Blocking intrauterine infection by telbivudine in pregnant chronic hepatitis B patients].
Topics: Administration, Oral; Antiviral Agents; DNA, Viral; Female; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Nucleosides; Pregnancy; Pregnancy Complications, Infectious; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome | 2009 |
Absence of effect of telbivudine on cardiac repolarization: results of a thorough QT/QTc study in healthy participants.
Topics: Adult; Antiviral Agents; Area Under Curve; Body Mass Index; Cross-Over Studies; Electrocardiography; Female; Hispanic or Latino; Humans; Male; Middle Aged; Nucleosides; Pyrimidinones; Sex Characteristics; Statistics as Topic; Telbivudine; Thymidine; Young Adult | 2009 |
Early viral kinetics of telbivudine and entecavir: results of a 12-week randomized exploratory study with patients with HBeAg-positive chronic hepatitis B.
Topics: Adult; Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Kinetics; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome | 2010 |
A 24-week, parallel-group, open-label, randomized clinical trial comparing the early antiviral efficacy of telbivudine and entecavir in the treatment of hepatitis B e antigen-positive chronic hepatitis B virus infection in adult Chinese patients.
Topics: Adult; Antiviral Agents; China; DNA, Viral; Female; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2010 |
[Clinical antiviral effects of telbivudine in patients with chronic hepatitis B].
Topics: Adult; Antiviral Agents; DNA, Viral; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome; Virus Replication | 2010 |
Efficacy of telbivudine in HBeAg-positive chronic hepatitis B patients with high baseline ALT levels.
Topics: Alanine Transaminase; Antiviral Agents; DNA, Viral; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2010 |
[Analysis of the prophylactic effect of nucleosides against reactivation of HBV in HBsAg-positive patients with non-hepatic tumors after chemotherapy].
Topics: Adult; Antineoplastic Agents; Antiviral Agents; Breast Neoplasms; Female; Follow-Up Studies; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Lamivudine; Lung Neoplasms; Lymphoma; Male; Middle Aged; Nucleosides; Pyrimidinones; Retrospective Studies; Telbivudine; Thymidine; Virus Activation | 2010 |
Efficacy of switching to telbivudine in chronic hepatitis B patients treated previously with lamivudine.
Topics: Adult; Antiviral Agents; Biomarkers; Chi-Square Distribution; DNA, Viral; Double-Blind Method; Drug Administration Schedule; Drug Resistance, Viral; Drug Substitution; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Time Factors; Treatment Outcome; Viral Load; Virus Replication | 2011 |
Complementarity-determining region 3 size spectratypes of T cell receptor beta chains in CD8+ T cells following antiviral treatment of chronic hepatitis B.
Topics: Adult; Antiviral Agents; CD8-Positive T-Lymphocytes; Complementarity Determining Regions; Double-Blind Method; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Lymphocyte Activation; Male; Nucleosides; Polymerase Chain Reaction; Pyrimidinones; Receptors, Antigen, T-Cell, alpha-beta; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2011 |
The diagnostic value of ultrasound elastography in patients with hepatitis B virus infection: a prospective study.
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Antiviral Agents; Asian People; China; Demography; Elasticity; Elasticity Imaging Techniques; Female; Hepatitis B; Hepatitis B virus; Humans; Hyaluronic Acid; Liver Cirrhosis; Male; Middle Aged; Nucleosides; Prospective Studies; Pyrimidinones; Telbivudine; Thymidine; Young Adult | 2010 |
[Efficacy of antiviral treatment on patients with acute-on-chronic hepatitis B liver failure with low viral load].
Topics: Adult; Antiviral Agents; End Stage Liver Disease; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Liver Failure, Acute; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Viral Load | 2010 |
Efficacy and safety of prolonged 3-year telbivudine treatment in patients with chronic hepatitis B.
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Antiviral Agents; Biomarkers; DNA, Viral; Drug Administration Schedule; Drug Resistance, Viral; Female; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Time Factors; Treatment Outcome; Viral Load; Young Adult | 2011 |
[Study on the efficacy and HBeAg seroconversion related factors of telbivudine and entecavir therapy in HBeAg positive chronic hepatitis B patients].
Topics: Adolescent; Adult; Antiviral Agents; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2011 |
A prospective and open-label study for the efficacy and safety of telbivudine in pregnancy for the prevention of perinatal transmission of hepatitis B virus infection.
Topics: Adult; Antiviral Agents; DNA, Viral; Female; Hepatitis B Antibodies; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B Vaccines; Hepatitis B, Chronic; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Male; Nucleosides; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2011 |
High serum IL-21 levels after 12 weeks of antiviral therapy predict HBeAg seroconversion in chronic hepatitis B.
Topics: Adult; Alanine Transaminase; Antiviral Agents; Biomarkers; Disease Progression; DNA, Viral; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interleukins; Male; Nucleosides; Pyrimidinones; Reproducibility of Results; Sensitivity and Specificity; Severity of Illness Index; Telbivudine; Thymidine; Treatment Outcome | 2012 |
Inhibition of viral replication downregulates CD4(+)CD25(high) regulatory T cells and programmed death-ligand 1 in chronic hepatitis B.
Topics: Adult; Antiviral Agents; B7-H1 Antigen; CD4-Positive T-Lymphocytes; Cytokines; Down-Regulation; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interleukin-2 Receptor alpha Subunit; Interleukin-9; Lymphocyte Count; Male; Nucleosides; Pyrimidinones; T-Lymphocytes, Regulatory; Telbivudine; Thymidine; Treatment Outcome; Viral Load; Virus Replication | 2012 |
Telbivudine prevents vertical transmission from HBeAg-positive women with chronic hepatitis B.
Topics: Adult; Antiviral Agents; Case-Control Studies; DNA, Viral; Female; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Incidence; Infant, Newborn; Infectious Disease Transmission, Vertical; Male; Nucleosides; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Pyrimidinones; Telbivudine; Thymidine | 2012 |
[Influences of warming kidney prescription on antiviral therapeutic efficacy and creatine kinase in telbivudine-treated HBeAg-positive chronic hepatitis B patients].
Topics: Adult; Antiviral Agents; Creatine Kinase; Female; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Phytotherapy; Pyrimidinones; Telbivudine; Thymidine | 2012 |
[Efficacy and safety of telbivudine in pregnant women to prevent perinatal transmission of hepatitis B virus].
Topics: Adult; DNA, Viral; Female; Hepatitis B; Hepatitis B virus; Humans; Infectious Disease Transmission, Vertical; Nucleosides; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Pyrimidinones; Telbivudine; Thymidine; Viral Load; Young Adult | 2012 |
[Efficacy and safety of telbivudine in pregnant chronic hepatitis B patients].
Topics: Adult; Antiviral Agents; Female; Hepatitis B, Chronic; Humans; Nucleosides; Pregnancy; Pregnancy Complications, Infectious; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2011 |
Lamivudine plus adefovir or telbivudine plus adefovir for chronic hepatitis B patients with suboptimal response to adefovir.
Topics: Adenine; Adult; Biomarkers; DNA, Viral; Drug Therapy, Combination; Female; Genotype; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Nucleosides; Organophosphonates; Prospective Studies; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2012 |
A randomized controlled trial of sequential pegylated interferon-α and telbivudine or vice versa for 48 weeks in hepatitis B e antigen-negative chronic hepatitis B.
Topics: Adult; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Administration Schedule; Drug Therapy, Combination; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Italy; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Telbivudine; Thymidine; Treatment Outcome | 2013 |
Randomized clinical trial: efficacy and safety of telbivudine and lamivudine in treatment-naïve patients with HBV-related decompensated cirrhosis.
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Double-Blind Method; Female; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Liver Failure; Male; Middle Aged; Multicenter Studies as Topic; Nucleosides; Prospective Studies; Pyrimidinones; Severity of Illness Index; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2012 |
Efficacy of telbivudine in Taiwanese chronic hepatitis B patients compared with GLOBE extension study and predicting treatment outcome by HBV DNA kinetics at week 24.
Topics: Adult; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Taiwan; Telbivudine; Thymidine; Time Factors | 2012 |
[Efficacy of telbivudine in blocking the vertical transmission and the safety observation of discontinuing treatment time after delivery on mother infected with HBV].
Topics: Adult; Antiviral Agents; Female; Hepatitis B; Humans; Infectious Disease Transmission, Vertical; Mothers; Pregnancy; Pregnancy Complications, Infectious; Telbivudine; Thymidine; Young Adult | 2012 |
52-week efficacy and safety of telbivudine with conditional tenofovir intensification at week 24 in HBeAg-positive chronic hepatitis B.
Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Administration Schedule; Drug Therapy, Combination; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Telbivudine; Tenofovir; Thymidine; Treatment Outcome; Virus Replication | 2013 |
[Efficacy and safety of telbivudine and adefovir dipivoxil for the treatment of chronic hepatitis B patients with high level hepatitis B virus load and hepatitis B e antigen-positivity].
Topics: Adenine; Adult; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Organophosphonates; Telbivudine; Thymidine; Treatment Outcome; Viral Load | 2012 |
Rapid downregulation of programmed death-1 and interferon-γ-inducible protein-10 expression is associated with favourable outcome during antiviral treatment of chronic hepatitis B.
Topics: Adult; Antiviral Agents; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Chemokine CXCL10; China; Cytokines; DNA, Viral; Down-Regulation; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-gamma; Male; Middle Aged; Programmed Cell Death 1 Receptor; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2013 |
Efficacy and safety of telbivudine plus adefovir dipivoxil combination therapy and entecavir monotherapy for HBeAg-positive chronic hepatitis B patients with resistance to adefovir dipivoxil.
Topics: Adenine; Adult; Antiviral Agents; China; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Organophosphonates; Prospective Studies; Telbivudine; Thymidine; Treatment Outcome | 2013 |
Efficacy of telbivudine treatment for hepatitis B e antigen-positive chronic hepatitis B patients with poor response to adefovir dipivoxil.
Topics: Adenine; Adult; Antiviral Agents; China; DNA, Viral; Drug Resistance, Viral; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Mutation; Organophosphonates; Telbivudine; Thymidine; Treatment Outcome; Viral Load; Virus Replication | 2013 |
Efficacy of sequential use of telbivudine in hepatitis B e antigen-positive chronic hepatitis B patients with partial responses to pegylated interferon: a pilot study.
Topics: Adult; Antiviral Agents; China; DNA, Viral; Drug Administration Schedule; Drug Therapy, Combination; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Pilot Projects; Polyethylene Glycols; Recombinant Proteins; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2013 |
Safety of telbivudine treatment for chronic hepatitis B for the entire pregnancy.
Topics: Adult; Antiviral Agents; China; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; Telbivudine; Thymidine; Treatment Outcome | 2013 |
Efficacy and safety of continuous 4-year telbivudine treatment in patients with chronic hepatitis B.
Topics: Adult; Antiviral Agents; Drug-Related Side Effects and Adverse Reactions; Female; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Telbivudine; Thymidine; Treatment Outcome | 2013 |
Antiviral therapy decreases viral reactivation in patients with hepatitis B virus-related hepatocellular carcinoma undergoing hepatectomy: a randomized controlled trial.
Topics: Adult; Antiviral Agents; Carcinoma, Hepatocellular; Female; Hepatectomy; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Telbivudine; Thymidine; Treatment Outcome; Viral Load; Virus Activation | 2013 |
Phase I, open-label, single-dose study to evaluate the pharmacokinetics and safety of telbivudine in children and adolescents with chronic hepatitis B.
Topics: Administration, Oral; Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Drug Administration Schedule; Drug Dosage Calculations; Female; Hepatitis B, Chronic; Humans; Male; Telbivudine; Thymidine | 2013 |
Efficacy and safety of telbivudine therapy in liver failure patients with chronic hepatitis B virus infection.
Topics: Adolescent; Adult; Aged; Antiviral Agents; DNA, Viral; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Failure; Liver Function Tests; Longitudinal Studies; Male; Middle Aged; Telbivudine; Thymidine; Treatment Outcome; Viral Load; Young Adult | 2013 |
Telbivudine and adefovir combination therapy for patients with chronic lamivudine-resistant hepatitis B virus infections.
Topics: Adenine; Adult; Aged; Antibodies, Viral; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Telbivudine; Thymidine; Treatment Outcome | 2014 |
Telbivudine improves renal function in patients with chronic hepatitis B.
Topics: Adult; Antiviral Agents; Creatinine; Double-Blind Method; Female; Glomerular Filtration Rate; Hepatitis B, Chronic; Humans; Male; Renal Insufficiency, Chronic; Telbivudine; Thymidine; Treatment Outcome | 2014 |
[Clinical observations of sequential interferon therapy following complete response to telbivudine treatment in chronic hepatitis B patients].
Topics: Adult; Female; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Recurrence; Telbivudine; Thymidine; Treatment Outcome; Viral Load; Young Adult | 2013 |
The 104-week efficacy and safety of telbivudine-based optimization strategy in chronic hepatitis B patients: a randomized, controlled study.
Topics: Adenine; Adolescent; Adult; Alanine Transaminase; Antiviral Agents; China; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Longitudinal Studies; Male; Middle Aged; Organophosphonates; Telbivudine; Thymidine; Time Factors; Treatment Outcome; Young Adult | 2014 |
Efficacy of switching to telbivudine plus adefovir in suboptimal responders to lamivudine plus adefovir.
Topics: Adenine; Administration, Oral; Adult; Aged; Antiviral Agents; Biomarkers; DNA, Viral; Drug Administration Schedule; Drug Resistance, Viral; Drug Substitution; Drug Therapy, Combination; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Patient Selection; Prospective Studies; Republic of Korea; Telbivudine; Thymidine; Time Factors; Treatment Failure; Viral Load; Young Adult | 2013 |
Comparing the efficacy and clinical outcome of telbivudine and entecavir naïve patients with hepatitis B virus-related compensated cirrhosis.
Topics: Adult; Aged; Alanine Transaminase; Antiviral Agents; Disease Progression; DNA, Viral; Female; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Humans; Liver Cirrhosis; Male; Middle Aged; Proportional Hazards Models; Risk Factors; Telbivudine; Thymidine; Time Factors; Treatment Outcome | 2014 |
[Long-term efficacy and safety of telbivudine as monotherapy and as combination therapy with adefovir dipivoxil in HBeAg-positive chronic hepatitis B patients].
Topics: Adenine; Adolescent; Adult; Antiviral Agents; Drug Therapy, Combination; Female; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Retrospective Studies; Telbivudine; Thymidine; Young Adult | 2014 |
Viral infection parameters not nucleoside analogue itself correlates with host immunity in nucleoside analogue therapy for chronic hepatitis B.
Topics: Adult; Antiviral Agents; Biomarkers; CD8-Positive T-Lymphocytes; China; Cytokines; DNA, Viral; Female; Forkhead Transcription Factors; Hepacivirus; Hepatitis B e Antigens; Hepatitis B, Chronic; Host-Pathogen Interactions; Humans; Immunity, Innate; Inflammation Mediators; Lamivudine; Male; Middle Aged; Programmed Cell Death 1 Receptor; T-Lymphocytes, Regulatory; Telbivudine; Thymidine; Time Factors; Treatment Outcome; Viral Load; Virus Replication | 2014 |
Telbivudine plus pegylated interferon alfa-2a in a randomized study in chronic hepatitis B is associated with an unexpected high rate of peripheral neuropathy.
Topics: Adult; Antiviral Agents; DNA, Viral; Drug Carriers; Drug Therapy, Combination; Female; Global Health; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Incidence; Interferon-alpha; Male; Peripheral Nervous System Diseases; Polyethylene Glycols; Recombinant Proteins; Telbivudine; Thymidine | 2015 |
Telbivudine or lamivudine use in late pregnancy safely reduces perinatal transmission of hepatitis B virus in real-life practice.
Topics: Adult; Antiviral Agents; Female; Follow-Up Studies; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2014 |
[Long-term efficacy and safety of telbivudine in the treatment of childbearing patients with chronic hepatitis B].
Topics: Adolescent; Adult; Antiviral Agents; Female; Hepatitis B, Chronic; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; Telbivudine; Thymidine; Young Adult | 2014 |
Telbivudine prevents vertical transmission of hepatitis B virus from women with high viral loads: a prospective long-term study.
Topics: Adolescent; Adult; Antiviral Agents; China; DNA, Viral; Female; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Longitudinal Studies; Male; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Telbivudine; Thymidine; Treatment Outcome; Viral Load; Young Adult | 2015 |
Significant renoprotective effect of telbivudine during preemptive antiviral therapy in advanced liver cancer patients receiving cisplatin-based chemotherapy: a case-control study.
Topics: Acute Kidney Injury; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Carcinoma, Hepatocellular; Cisplatin; Female; Fluorouracil; Hepatitis B, Chronic; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Male; Middle Aged; Mitomycin; Protective Agents; Telbivudine; Thymidine; Treatment Outcome | 2014 |
Cost-effectiveness analysis of lamivudine, telbivudine, and entecavir in treatment of chronic hepatitis B with adefovir dipivoxil resistance.
Topics: Adenine; Adult; Antiviral Agents; Cost-Benefit Analysis; Double-Blind Method; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Prospective Studies; Telbivudine; Thymidine | 2015 |
Long-Term Telbivudine Treatment Results in Resolution of Liver Inflammation and Fibrosis in Patients with Chronic Hepatitis B.
Topics: Adult; Antiviral Agents; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Inflammation; Liver; Liver Cirrhosis; Male; Middle Aged; Telbivudine; Thymidine; Time; Treatment Outcome | 2015 |
Resistant mutations and quasispecies complexity of hepatitis B virus during telbivudine treatment.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Drug Resistance, Viral; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Mutation; Telbivudine; Thymidine; Young Adult | 2015 |
Cost-effectiveness of Lamivudine, Telbivudine, Adefovir Dipivoxil and Entecavir on decompensated hepatitis B virus-related cirrhosis.
Topics: Adenine; Adult; Antiviral Agents; Cost-Benefit Analysis; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Male; Middle Aged; Organophosphonates; Telbivudine; Thymidine; Treatment Outcome | 2016 |
[Effect of Telbivudine Tablet Combined Jianpi Bushen Recipe on HBV Specific Cytotoxic T Lymphocyte and HBeAg Seroconversion in Patients with HBeAg Positive Chronic Hepatitis B].
Topics: Drug Therapy, Combination; Drugs, Chinese Herbal; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Seroconversion; T-Lymphocytes, Cytotoxic; Tablets; Telbivudine; Thymidine | 2016 |
[Efficacy of 104-week sequential therapy with telbivudine or entecavir in HBeAg-positive chronic hepatitis B patients with suboptimal responses to 24-week therapy with pegylated interferon-α-2a].
Topics: Antiviral Agents; DNA, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Male; Polyethylene Glycols; Recombinant Proteins; Telbivudine; Thymidine; Treatment Outcome | 2016 |
Comparison of Telbivudine and Entecavir Therapy on Nephritic Function and Drug Resistance in Patients with Hepatitis B Virus-Related Compensated Cirrhosis.
Topics: Creatinine; DNA, Viral; Drug Resistance, Viral; Female; Glomerular Filtration Rate; Guanine; Hepatitis B virus; Humans; Kidney; Kidney Function Tests; Liver Cirrhosis; Male; Middle Aged; Telbivudine; Thymidine | 2016 |
Entecavir to Telbivudine Switch Therapy in Entecavir-Treated Patients with Undetectable Hepatitis B Viral DNA.
Topics: Adult; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug Substitution; Female; Follow-Up Studies; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Mutation; Polymerase Chain Reaction; Prospective Studies; Telbivudine; Thymidine; Treatment Outcome; Viral Load | 2017 |
Telbivudine treatment started in early and middle pregnancy completely blocks HBV vertical transmission.
Topics: Adult; Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Infant, Newborn; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, First; Pregnancy Trimester, Second; Telbivudine; Thymidine; Viral Load; Young Adult | 2017 |
Interpretation of liver stiffness measurement-based approach for the monitoring of hepatitis B patients with antiviral therapy: A 2-year prospective study.
Topics: Adolescent; Adult; Alanine Transaminase; Antiviral Agents; Biopsy; Drug Monitoring; Drug Therapy, Combination; Elasticity Imaging Techniques; Female; Hepatitis B, Chronic; Humans; Liver; Liver Cirrhosis; Longitudinal Studies; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Telbivudine; Thymidine; Young Adult | 2018 |
Comparison of 208-week sequential therapy with telbivudine and entecavir in HBeAg-positive chronic hepatitis B patients with suboptimal responses to 24 weeks of Peg-IFNα-2a therapy: An open-labelled, randomized, controlled, "real-life" trial.
Topics: Adult; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Liver Function Tests; Male; Polyethylene Glycols; Proportional Hazards Models; Recombinant Proteins; Seroconversion; Telbivudine; Thymidine; Treatment Outcome; Viral Load | 2017 |
219 other study(ies) available for thymidine and telbivudine
| Article | Year |
|---|---|
Telbivudine (Tyzeka) for chronic Hepatitis B.
Topics: Antiviral Agents; Clinical Trials as Topic; Drug Resistance, Viral; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2007 |
Telbivudine.
Topics: Antiviral Agents; Enzyme Inhibitors; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Randomized Controlled Trials as Topic; Telbivudine; Thymidine | 2007 |
Drug profile: telbivudine (Tyzeka).
Topics: Antiviral Agents; Dose-Response Relationship, Drug; Drug Resistance, Viral; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Randomized Controlled Trials as Topic; Telbivudine; Thymidine; Treatment Outcome | 2007 |
[New first line therapy of chronic hepatitis B. Primary therapy goal: effective virus suppression].
Topics: Antiviral Agents; Clinical Trials as Topic; DNA, Viral; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Virus Replication | 2007 |
[Treatment in every detected virus replication. New guideline for therapy of hepatitis B publicized].
Topics: Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver Cirrhosis; Nucleosides; Practice Guidelines as Topic; Pyrimidinones; Telbivudine; Thymidine; Virus Replication | 2007 |
[New German and American guidelines for therapy of hepatitis B. Discrepancies and similarities].
Topics: Adenine; Alanine Transaminase; Antiviral Agents; Biopsy; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Germany; Guanine; Hepatitis B; Humans; Lamivudine; Liver; Liver Cirrhosis; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pyrimidinones; Telbivudine; Thymidine; United States | 2007 |
Summaries for patients. Antiviral therapy for chronic hepatitis B.
Topics: Adenine; Adolescent; Adult; Aged; Antiviral Agents; Biomarkers; DNA, Viral; Drug Therapy, Combination; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Thymidine; Viral Load | 2007 |
[Several important issues on drug resistance of hepatitis B virus].
Topics: Antiviral Agents; Drug Resistance, Viral; Hepatitis B; Hepatitis B virus; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2007 |
Enantio-selectivity of human nucleoside monophosphate kinases.
Topics: Antiviral Agents; Humans; Nucleoside-Phosphate Kinase; Nucleosides; Pyrimidine Nucleosides; Pyrimidinones; Stereoisomerism; Telbivudine; Thymidine | 2007 |
[Anti-viral therapy of type B chronic hepatitis. 3. Future of anti-viral agents].
Topics: Adenine; Antiviral Agents; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Hepatitis B, Chronic; Humans; Interferons; Nucleic Acid Synthesis Inhibitors; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine | 2008 |
Telbivudine versus lamivudine in patients with chronic hepatitis B.
Topics: Antiviral Agents; Drug Resistance, Viral; Genotype; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Mutation; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Viral Load | 2008 |
Nonclinical safety profile of telbivudine, a novel potent antiviral agent for treatment of hepatitis B.
Topics: Administration, Oral; Animals; Antiviral Agents; Carcinogenicity Tests; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Tolerance; Female; Hepatitis B, Chronic; Humans; Macaca fascicularis; Male; Mice; Mice, Transgenic; Mutagenicity Tests; Nerve Degeneration; Nucleosides; Pregnancy; Pyrimidinones; Rabbits; Rats; Rats, Sprague-Dawley; Reproduction; Safety; Telbivudine; Thymidine | 2008 |
[Chinese roadmap for treating chronic hepatitis B with telbivudine].
Topics: Antiviral Agents; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2008 |
Clinical features of adverse reactions associated with telbivudine.
Topics: Adult; Arrhythmias, Cardiac; Creatine Kinase; Drug Synergism; Hepatitis B, Chronic; Humans; Interferons; Male; Middle Aged; Muscle Weakness; Neuralgia; Nucleosides; Pyrimidinones; Retrospective Studies; Risk Factors; Telbivudine; Thymidine | 2008 |
Programmed death 1 expression during antiviral treatment of chronic hepatitis B: Impact of hepatitis B e-antigen seroconversion.
Topics: Adult; Alanine Transaminase; Antigens, CD; Antiviral Agents; Apoptosis Regulatory Proteins; Biopsy; CD8-Positive T-Lymphocytes; DNA, Viral; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-gamma; Interleukin-10; Lamivudine; Liver; Longitudinal Studies; Male; Middle Aged; Nucleosides; Programmed Cell Death 1 Receptor; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome; Viral Load; Viremia | 2008 |
Telbivudine, a nucleoside analog inhibitor of HBV polymerase, has a different in vitro cross-resistance profile than the nucleotide analog inhibitors adefovir and tenofovir.
Topics: Adenine; Amino Acid Substitution; Antiviral Agents; Cell Line, Tumor; Drug Resistance, Viral; Gene Products, pol; Hepatitis B virus; Humans; Microbial Sensitivity Tests; Mutation, Missense; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2009 |
[New treatment of chronic hepatitis B].
Topics: Antiviral Agents; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine | 2008 |
[The effect of telbivudine on peripheral blood CD4+CD25+ regulatory T cells and its significance in patients with chronic hepatitis B].
Topics: Adolescent; Adult; Antiviral Agents; Case-Control Studies; Female; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interleukin-2 Receptor alpha Subunit; Middle Aged; Nucleosides; Pyrimidinones; T-Lymphocytes, Regulatory; Telbivudine; Thymidine; Young Adult | 2008 |
Hepatitis B: a "GLOBAL" health challenge.
Topics: Antiviral Agents; DNA, Viral; Global Health; Hepatitis B; Hepatitis B virus; Humans; Lamivudine; Nucleosides; Patient Selection; Pyrimidinones; Randomized Controlled Trials as Topic; Telbivudine; Thymidine; Virus Replication | 2009 |
Telbivudine has activity against HIV-1.
Topics: Anti-HIV Agents; Hepatitis B, Chronic; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2009 |
The rtA194T polymerase mutation impacts viral replication and susceptibility to tenofovir in hepatitis B e antigen-positive and hepatitis B e antigen-negative hepatitis B virus strains.
Topics: Adenine; Anti-HIV Agents; Cell Line, Tumor; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Humans; Lamivudine; Mutation; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Viral Proteins; Virus Replication | 2009 |
[Methodical recommendations of Asian-Pacific Association for Studying the Liver (APASL) concerning treatment of the viral hepatitis B (HBV)].
Topics: Antiviral Agents; Asia; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Liver Function Tests; Nucleosides; Pacific Islands; Practice Guidelines as Topic; Pyrimidinones; Recombinant Proteins; Severity of Illness Index; Telbivudine; Thymidine | 2008 |
[Dynamic changes of Th1/Th2 type cytokines in peripheral blood of patients with hepatitis B e antigen-positive chronic hepatitis B treated with telbivudine].
Topics: Adult; Antiviral Agents; DNA, Viral; Female; Flow Cytometry; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-gamma; Interleukins; Male; Nucleosides; Pyrimidinones; Telbivudine; Th1 Cells; Th2 Cells; Thymidine; Time Factors; Tumor Necrosis Factor-alpha; Young Adult | 2009 |
Perspectives on the management of chronic hepatitis B and C.
Topics: Antiviral Agents; Enzyme Inhibitors; Hepacivirus; Hepatitis B virus; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Immunoglobulins; Interferons; Mental Disorders; Nucleosides; Pyrimidinones; Substance-Related Disorders; Telbivudine; Thymidine | 2009 |
Anti-hepatitis B virus activity in vitro of combinations of tenofovir with nucleoside/nucleotide analogues.
Topics: Adenine; Antiviral Agents; Cell Line; Cell Survival; Deoxycytidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Nucleotides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine | 2009 |
Population pharmacokinetics of telbivudine and determination of dose adjustment for patients with renal impairment.
Topics: Adult; Aged; Antiviral Agents; Biological Availability; Female; Humans; Kidney Diseases; Male; Middle Aged; Models, Biological; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2009 |
Treatment with nucleos(t)ide analogues in chronic hepatitis B: where does the road map lead us?
Topics: Antiviral Agents; DNA, Viral; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2009 |
[Symposium on clinical application of telbivudine].
Topics: Antiviral Agents; Congresses as Topic; DNA, Viral; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Nucleosides; Patient Compliance; Pyrimidinones; Telbivudine; Thymidine | 2009 |
Different models of HBeAg seroconversion predicated by on-treatment ALT and HBV DNA profiles.
Topics: Adenine; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Nucleosides; Organophosphonates; Prognosis; Pyrimidinones; Retrospective Studies; Telbivudine; Thymidine; Young Adult | 2009 |
[Pharmacoeconomic evaluation of telbivudine vs. lamivudine in treating the patients with HBeAg-positive and negative chronic hepatitis B].
Topics: Adult; Antifungal Agents; China; Cost-Benefit Analysis; DNA, Viral; Drug Costs; Economics, Pharmaceutical; Female; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Insurance, Long-Term Care; Lamivudine; Liver Cirrhosis; Male; Markov Chains; Middle Aged; Models, Economic; Nucleosides; Prescription Drugs; Pyrimidinones; Quality-Adjusted Life Years; Telbivudine; Thymidine | 2009 |
Hepatitis B in HIV patients: what is the current treatment and what are the challenges?
Topics: Adenine; Antiviral Agents; Deoxycytidine; DNA, Viral; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; HIV Infections; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Cirrhosis; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine; Transaminases | 2009 |
[Telbivudine in the management of HIV/HBV coinfection. Treating hepatitis B without HIV trouble].
Topics: Adenine; AIDS-Related Opportunistic Infections; Algorithms; Anti-HIV Agents; Antiviral Agents; Comorbidity; DNA, Viral; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver Function Tests; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Thymidine | 2009 |
Telbivudine in the treatment of chronic hepatitis B: experience in HIV type-1-infected patients naive for antiretroviral therapy.
Topics: Adult; Anti-HIV Agents; Antiviral Agents; Hepatitis B, Chronic; HIV Infections; HIV-1; Humans; Male; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2009 |
[The efficacy of nucleoside/nucleotide analogue on chronic hepatitis B].
Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Treatment Outcome; Virus Replication | 2009 |
[Preliminary clinical study of efficacy on re-treatment for interferon suboptimal CHB patients].
Topics: Administration, Oral; Adult; Alanine Transaminase; DNA, Viral; Female; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferons; Male; Nucleosides; Pyrimidinones; Retreatment; Telbivudine; Thymidine; Treatment Outcome; Virus Replication | 2009 |
Telbivudine use in a patient affected by occult hepatitis B virus and B-cell non-Hodgkin lymphoma.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Biomarkers, Tumor; Cyclophosphamide; DNA; Hepatitis B; Hepatitis B virus; Humans; Lymphoma, B-Cell; Male; Middle Aged; Nucleosides; Prednisolone; Proto-Oncogene Proteins c-bcl-2; Pyrimidinones; Rituximab; Telbivudine; Thymidine; Vincristine | 2010 |
On-treatment serum HBsAg level is predictive of sustained off-treatment virologic response to telbivudine in HBeAg-positive chronic hepatitis B patients.
Topics: Adolescent; Adult; Antiviral Agents; DNA, Viral; Female; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Multivariate Analysis; Nucleosides; Predictive Value of Tests; Pyrimidinones; ROC Curve; Statistics, Nonparametric; Telbivudine; Thymidine; Treatment Outcome; Viral Load | 2010 |
Telbivudine exhibits no inhibitory activity against HIV-1 clinical isolates in vitro.
Topics: Anti-HIV Agents; Antiviral Agents; Drug Resistance, Viral; Guanine; Hepatitis B virus; Hepatitis B, Chronic; HIV Infections; HIV-1; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2010 |
Cost-effectiveness analysis of roadmap models in chronic hepatitis B using tenofovir as the rescue therapy.
Topics: Adenine; Antiviral Agents; Asia; Cost-Benefit Analysis; Decision Support Techniques; DNA, Viral; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Germany; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Models, Economic; Nucleosides; Organophosphonates; Pyrimidinones; Salvage Therapy; Telbivudine; Tenofovir; Thymidine; Treatment Outcome; United States | 2010 |
Application of hepatitis B virus replication mouse model.
Topics: Animals; Antiviral Agents; Disease Models, Animal; Drug Resistance, Viral; Enzyme-Linked Immunosorbent Assay; Hepatitis B; Hepatitis B virus; Humans; Liver; Male; Mice; Mice, Inbred BALB C; Mutation; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Virus Replication | 2010 |
Viral resistance in hepatitis B: prevalence and management.
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Genetic Testing; Genotype; Guanine; Hepatitis B; Humans; Lamivudine; Nucleosides; Organophosphonates; Phenotype; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2010 |
Evaluation of the in vitro anti-HBV activity of clevudine in combination with other nucleoside/nucleotide inhibitors.
Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Arabinofuranosyluracil; Cell Line; Cells, Cultured; Drug Antagonism; Drug Synergism; Drug Therapy, Combination; Guanine; Hepatitis B virus; Hepatocytes; Humans; Lamivudine; Microbial Sensitivity Tests; Nucleosides; Nucleotides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine | 2010 |
Cost-effectiveness of nucleoside analog therapy for hepatitis B in China: a Markov analysis.
Topics: Adenine; Antiviral Agents; China; Cost-Benefit Analysis; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Markov Chains; Models, Economic; Models, Statistical; Monte Carlo Method; Nucleosides; Organophosphonates; Pyrimidinones; Quality-Adjusted Life Years; Reverse Transcriptase Inhibitors; Serologic Tests; Telbivudine; Thymidine | 2010 |
Telbivudine preserves T-helper 1 cytokine production and downregulates programmed death ligand 1 in a mouse model of viral hepatitis.
Topics: Animals; Antiviral Agents; B7-H1 Antigen; Cells, Cultured; Cytokines; Female; Hepatitis, Viral, Animal; Immunologic Factors; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Murine hepatitis virus; Nucleosides; Pyrimidinones; Survival Analysis; Telbivudine; Th1 Cells; Thymidine | 2010 |
[Icteric hepatitis in a patient with non-Hodgkin's lymphoma treated by rituximab-based chemotherapy].
Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Cyclophosphamide; Cytomegalovirus; Cytomegalovirus Infections; Doxorubicin; Hepatitis B virus; Hepatitis B, Chronic; Humans; Hyperbilirubinemia; Immunocompromised Host; Immunosuppressive Agents; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Nucleosides; Prednisone; Pyrimidinones; Rituximab; Telbivudine; Thymidine; Vincristine; Viremia; Virus Activation | 2010 |
Dynamic analysis of CD127 expression on memory CD8 T cells from patients with chronic hepatitis B during telbivudine treatment.
Topics: Adult; Antiviral Agents; CD8-Positive T-Lymphocytes; DNA, Viral; Female; Gene Expression Profiling; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunologic Memory; Interleukin-7 Receptor alpha Subunit; Male; Nucleosides; Pyrimidinones; T-Lymphocyte Subsets; Telbivudine; Thymidine | 2010 |
Kinetics of hepatitis B surface antigen decline during 3 years of telbivudine treatment in hepatitis B e antigen-positive patients.
Topics: Adult; Antiviral Agents; Body Weight; Enzyme-Linked Immunosorbent Assay; Genotype; Hepatitis B Core Antigens; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Kinetics; Liver; Lymphocyte Activation; Nucleosides; Patient Selection; Pyrimidinones; Racial Groups; T-Lymphocytes; Telbivudine; Thymidine; Time Factors | 2010 |
Telbivudine: rhabdomyolysis and neuropathy.
Topics: Antiviral Agents; Hepatitis B, Chronic; Humans; Nucleosides; Peripheral Nervous System Diseases; Pyrimidinones; Rhabdomyolysis; Telbivudine; Thymidine | 2010 |
[Programmed death-1 (PD-1) and PD-L1 expression during antiviral treatment of chronic hepatitis B].
Topics: Adult; Antiviral Agents; B7-H1 Antigen; CD8-Positive T-Lymphocytes; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Nucleosides; Programmed Cell Death 1 Receptor; Pyrimidinones; Telbivudine; Thymidine; Young Adult | 2010 |
[A study on the factors correlated to virological response in chronic hepatitis B patients with telbivudine treatment].
Topics: Adolescent; Adult; Antiviral Agents; DNA, Viral; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Young Adult | 2010 |
Myotoxicity of telbivudine in pre-existing muscle damage.
Topics: Adult; Antiviral Agents; Creatine Kinase; Hepatitis B; Humans; Male; Muscle, Skeletal; Muscular Diseases; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2010 |
[Analogs combination therapy in chronic hepatitis B: when and how?].
Topics: Adenine; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combination; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2010 |
[Long-term therapy for chronic hepatitis B in HIV co-infected patients].
Topics: Adenine; Antiretroviral Therapy, Highly Active; Antiviral Agents; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B, Chronic; HIV Infections; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine | 2010 |
Significance of HBV DNA levels at 12 weeks of telbivudine treatment and the 3 years treatment outcome.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Follow-Up Studies; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Mutation; Nucleosides; Predictive Value of Tests; Pyrimidinones; Telbivudine; Thymidine; Time Factors; Treatment Outcome; Viral Load; Young Adult | 2011 |
Profile of HBV antiviral resistance mutations with distinct evolutionary pathways against nucleoside/nucleotide analogue treatment among Chinese chronic hepatitis B patients.
Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; China; Cross-Sectional Studies; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Molecular Typing; Mutation, Missense; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine; Young Adult | 2010 |
Treatment of HBeAg-negative chronic hepatitis B patients with nucleos(t)ide analogues.
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Time Factors; Treatment Outcome | 2011 |
Correlation between the Elecsys HBsAg II assay and the Architect assay for the quantification of hepatitis B surface antigen (HBsAg) in the serum.
Topics: Clinical Laboratory Techniques; Drug Resistance, Viral; Genotype; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunoassay; Lamivudine; Longitudinal Studies; Mutation; Nucleosides; Pyrimidinones; Reagent Kits, Diagnostic; Telbivudine; Thymidine | 2011 |
Genotypic resistance profile of hepatitis B virus (HBV) in a large cohort of nucleos(t)ide analogue-experienced Chinese patients with chronic HBV infection.
Topics: Adenine; Adult; Amino Acid Substitution; Antiviral Agents; China; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation, Missense; Nucleosides; Organophosphonates; Pyrimidinones; RNA-Directed DNA Polymerase; Sequence Analysis, DNA; Telbivudine; Thymidine; Viral Proteins | 2011 |
Treatment of chronic hepatitis B with telbivudine: wise hepatologists needed in hepatitis B endemic countries where treatment options are limited.
Topics: Antiviral Agents; Biomarkers; DNA, Viral; Drug Resistance, Viral; Drug Substitution; Endemic Diseases; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Time Factors; Treatment Outcome; Viral Load | 2011 |
[New insight for HBV DNA and HBsAg quantitation during antiviral therapy in patients with chronic hepatitis B].
Topics: Antiviral Agents; Carcinoma, Hepatocellular; DNA, Viral; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2011 |
Effect of telbivudine therapy on the cellular immune response in chronic hepatitis B.
Topics: Adult; Alanine Transaminase; Antiviral Agents; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; Cytokines; DNA, Viral; Enzyme-Linked Immunospot Assay; Female; Hepatitis B Core Antigens; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunity, Cellular; Liver; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Treatment Outcome | 2011 |
Two patterns of alanine aminotransferase increase to predict long-term viral response in chronic hepatitis B patients: virus- or host-induced?
Topics: Adenine; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Guanine; Hepacivirus; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-gamma; Lamivudine; Male; Middle Aged; Nucleosides; Organophosphonates; Predictive Value of Tests; Pyrimidinones; T-Lymphocytes; Telbivudine; Thymidine; Treatment Outcome; Up-Regulation; Young Adult | 2011 |
Rhabdomyolysis in a 48-year-old man with hepatitis B-induced cirrhosis.
Topics: Acute Kidney Injury; Antiviral Agents; Fatal Outcome; Fibrosis; Hepatitis B; Humans; Male; Middle Aged; Muscular Diseases; Nucleosides; Pyrimidinones; Rhabdomyolysis; Telbivudine; Thymidine; Treatment Outcome | 2011 |
HBV treatment and pregnancy.
Topics: Female; Hepatitis B, Chronic; Humans; Infectious Disease Transmission, Vertical; Male; Nucleosides; Pregnancy; Pregnancy Complications, Infectious; Pyrimidinones; Telbivudine; Thymidine | 2011 |
Effects of antiviral therapy with Telbivudine on peripheral iNKT cells in HBeAg(+) chronic hepatitis B patients.
Topics: Adult; Antiviral Agents; Female; Gene Expression Profiling; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Immunologic Factors; Interferon-gamma; Male; Middle Aged; Natural Killer T-Cells; Nucleosides; Programmed Cell Death 1 Receptor; Pyrimidinones; Telbivudine; Thymidine | 2012 |
Telbivudine exerts no antiviral activity against HIV-1 in vitro and in humans.
Topics: Adult; Antiviral Agents; CD4 Lymphocyte Count; Cell Line; Coinfection; DNA, Viral; Drug Resistance, Viral; Genotype; HEK293 Cells; Hepatitis B virus; Hepatitis B, Chronic; HIV Infections; HIV-1; Humans; Male; Middle Aged; Nucleosides; Phenotype; Pyrimidinones; RNA, Viral; Telbivudine; Thymidine; Viral Load | 2011 |
Clinical features and risk factors of creatine kinase elevations and myopathy associated with telbivudine.
Topics: Adolescent; Adult; Age Distribution; Aged; Antiviral Agents; Creatine Kinase; Female; Hepatitis B, Chronic; Humans; Incidence; Male; Middle Aged; Muscular Diseases; Nucleosides; Pyrimidinones; Risk Factors; Sex Distribution; Telbivudine; Thymidine; Young Adult | 2011 |
[New drugs of treatment of patients with chronic hepatitis B].
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Emtricitabine; Hepatitis B, Chronic; Humans; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2011 |
A comparison of telbivudine and entecavir for chronic hepatitis B in real-world clinical practice.
Topics: Adult; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Time Factors; Treatment Outcome; Viral Load | 2012 |
Restored circulating invariant NKT cells are associated with viral control in patients with chronic hepatitis B.
Topics: Adult; Case-Control Studies; CD4-Positive T-Lymphocytes; Cell Movement; Cytokines; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Natural Killer T-Cells; Nucleosides; Pyrimidinones; Receptors, CCR5; Receptors, CCR6; Telbivudine; Thymidine; Young Adult | 2011 |
Uncover the immune biomarkers underlying hepatitis B e antigen (HBeAg) seroconversion: a need for more translational study.
Topics: Antiviral Agents; Female; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interleukins; Male; Nucleosides; Pyrimidinones; Telbivudine; Thymidine | 2012 |
Telbivudine improves the function of myeloid dendritic cells in patients with chronic hepatitis B.
Topics: Adult; Antigens, CD; Antiviral Agents; B7-H1 Antigen; Cells, Cultured; Dendritic Cells; Down-Regulation; Gene Expression; Hepatitis B Antigens; Hepatitis B, Chronic; HLA-DR Antigens; Humans; Interferon-alpha; Interleukin-12; Male; Monocytes; Myeloid Cells; Nucleosides; Pyrimidinones; Telbivudine; Thymidine; Up-Regulation; Virus Replication | 2012 |
Telbivudine myopathy in a patient with chronic hepatitis B.
Topics: Adult; Antiviral Agents; Hepatitis B, Chronic; Humans; Male; Muscular Diseases; Telbivudine; Thymidine | 2012 |
Interruption of mother-to-infant transmission of hepatitis B: time to include selective antiviral prophylaxis?
Topics: Antiviral Agents; Developing Countries; Female; Hepatitis B; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Nucleosides; Pregnancy; Pregnancy Complications, Infectious; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine; Vaccination | 2012 |
Effects of telbivudine treatment on the circulating CD4⁺ T-cell subpopulations in chronic hepatitis B patients.
Topics: Adult; Antiviral Agents; Case-Control Studies; CD4-Positive T-Lymphocytes; Cytokines; Female; Hepatitis B, Chronic; Humans; Immune System; Interferon-gamma; Leukocytes, Mononuclear; Male; Middle Aged; Nucleosides; Pyrimidinones; Telbivudine; Th17 Cells; Thymidine; Time Factors | 2012 |
[Influence of adefovir dipivoxil or telbivudine monotherapy on renal function of patients with chronic hepatitis B].
Topics: Adenine; Adolescent; Adult; Creatinine; Female; Glomerular Filtration Rate; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Retrospective Studies; Telbivudine; Thymidine; Young Adult | 2012 |
Current practice of chronic hepatitis B treatment in Southern Italy.
Topics: Adenine; Adult; Age Factors; Aged; Aged, 80 and over; Antiviral Agents; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Italy; Lamivudine; Male; Middle Aged; Nucleosides; Organophosphonates; Polyethylene Glycols; Practice Patterns, Physicians'; Pyrimidinones; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine; Young Adult | 2012 |
Acute liver failure resulting from discontinuation of nucleoside analogues in chronic hepatitis B patients: a report of two cases.
Topics: Adenine; Adult; Antiviral Agents; Guanine; Hepatitis B, Chronic; Histocytochemistry; Humans; Lamivudine; Liver Failure, Acute; Liver Transplantation; Male; Medication Adherence; Necrosis; Organophosphonates; Telbivudine; Thymidine | 2013 |
Telbivudin as prophylaxis for hepatitis B virus recurrence after liver transplantation: a case series in single-center experience.
Topics: Adult; Case-Control Studies; Female; Hepatitis B; Humans; Liver Transplantation; Male; Middle Aged; Nucleosides; Pyrimidinones; Recurrence; Telbivudine; Thymidine; Viral Load | 2012 |
The 2012 revised Dutch national guidelines for the treatment of chronic hepatitis B virus infection.
Topics: Adenine; Antiviral Agents; Drug Approval; Drug Resistance, Viral; Female; Guanine; Hepatitis B, Chronic; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Milk, Human; Netherlands; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Infectious; Renal Insufficiency; Telbivudine; Tenofovir; Thymidine | 2012 |
Severe acute hepatitis B in a treatment-naïve patient with antiviral drug resistant mutations in the polymerase gene.
Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Genotype; Hepatitis B; Hepatitis B Antibodies; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Italy; Lamivudine; Male; Middle Aged; Mutation, Missense; Organophosphonates; Telbivudine; Tenofovir; Thailand; Thymidine; Travel; Treatment Outcome | 2013 |
Telbivudine in the treatment of hepatitis B-associated cryoglobulinemia.
Topics: Aged; Alanine Transaminase; Antiviral Agents; CD4-CD8 Ratio; Cryoglobulinemia; Cryoglobulins; DNA, Viral; Female; Hepatitis B, Chronic; Humans; Male; Middle Aged; Telbivudine; Thymidine; Treatment Outcome | 2013 |
[Telbivudine-associated creatine kinase elevation in chronic hepatitis B patients].
Topics: Adolescent; Adult; Aged; Antiviral Agents; Creatine Kinase; Hepatitis B, Chronic; Humans; Middle Aged; Telbivudine; Thymidine; Young Adult | 2012 |
Treatment with telbivudine positively regulates antiviral immune profiles in Chinese patients with chronic hepatitis B.
Topics: Administration, Oral; Adult; Alanine Transaminase; Antigens, CD; Antiviral Agents; Asian People; Aspartate Aminotransferases; Biomarkers; Case-Control Studies; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; DNA, Viral; Female; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Killer Cells, Natural; Lymphocyte Count; Male; Middle Aged; Telbivudine; Thymidine | 2013 |
Hepatitis B e antigen-suppressing mutations enhance the replication efficiency of adefovir-resistant hepatitis B virus strains.
Topics: Adenine; Antiviral Agents; Cell Line, Tumor; Drug Resistance, Viral; Gene Products, pol; Hepatitis B e Antigens; Hepatitis B virus; Humans; Mutation; Organophosphonates; Promoter Regions, Genetic; Telbivudine; Tenofovir; Thymidine; Virus Replication | 2013 |
Kinetics and prediction of HBsAg loss during therapy with analogues in patients affected by chronic hepatitis B HBeAg negative and genotype D.
Topics: Adenine; Aged; Antiviral Agents; Biomarkers; Chi-Square Distribution; DNA, Viral; Female; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Kinetics; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2013 |
Telbivudine plus adefovir therapy for chronic hepatitis B patients with virological breakthrough or genotypic resistance to telbivudine.
Topics: Adenine; Antiviral Agents; Biomarkers; Chi-Square Distribution; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Organophosphonates; Phenotype; Telbivudine; Thymidine; Time Factors; Treatment Outcome; Viral Load; Virus Replication | 2013 |
A different look at the management of chronic hepatitis B in a resource-constrained country.
Topics: Adenine; Antiviral Agents; China; Drug Therapy, Combination; Health Resources; Hepatitis B virus; Hepatitis B, Chronic; Humans; Organophosphonates; Telbivudine; Thymidine | 2013 |
Forty-eight-week retrospective study of telbivudine and lamivudine treatment in patients with hepatitis B-related cirrhosis.
Topics: Adolescent; Adult; Aged; Antiviral Agents; DNA, Viral; Female; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Humans; Lamivudine; Liver Cirrhosis; Male; Middle Aged; Retrospective Studies; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2013 |
Efficacy of entecavir switch therapy in chronic hepatitis B patients with incomplete virological response to telbivudine.
Topics: Adult; Antiviral Agents; Drug Resistance, Viral; Drug Substitution; Female; Follow-Up Studies; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Mutation; Retrospective Studies; Risk Factors; Telbivudine; Thymidine; Treatment Outcome | 2013 |
Dynamics of hepatitis B virus quasispecies heterogeneity and virologic response in patients receiving low-to-moderate genetic barrier nucleoside analogs.
Topics: Adult; Antiviral Agents; DNA, Viral; Female; Genetic Variation; Genotype; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Nucleosides; Point Mutation; RNA-Directed DNA Polymerase; Sequence Analysis, DNA; Telbivudine; Thymidine; Treatment Outcome | 2013 |
Increased eGFR with telbivudine in combination therapy of chronic hepatitis B infection.
Topics: Adenine; Antiviral Agents; Drug Therapy, Combination; Glomerular Filtration Rate; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Telbivudine; Tenofovir; Thymidine | 2014 |
Snapshot on drug-resistance rate and profiles in patients with chronic hepatitis B receiving nucleos(t)ide analogues in clinical practice.
Topics: Adenine; Adult; Antiviral Agents; Cohort Studies; DNA, Viral; Drug Resistance, Viral; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Recurrence; Telbivudine; Thymidine; Treatment Outcome | 2013 |
Two cases of telbivudine-induced myopathy in siblings with chronic hepatitis B.
Topics: Adult; Antiviral Agents; Creatine Kinase; Electromyography; Hepatitis B, Chronic; Humans; Male; Muscle, Skeletal; Muscular Diseases; Siblings; Telbivudine; Thymidine | 2013 |
Treatment with telbivudine for fulminant hepatitis B.
Topics: Acute Disease; Adult; Antiviral Agents; Female; Hepatitis B; Humans; Liver Failure, Acute; Telbivudine; Thymidine; Treatment Outcome | 2013 |
Quantification of hepatitis B surface antigen and E antigen: correlation between Elecsys and architect assays.
Topics: Antiviral Agents; Genotype; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Phylogeny; Reagent Kits, Diagnostic; Reproducibility of Results; Sensitivity and Specificity; Statistics, Nonparametric; Telbivudine; Thymidine | 2013 |
A comparison of efficacy and safety of 2-year telbivudine and entecavir treatment in patients with chronic hepatitis B: a match-control study.
Topics: Adult; Aged; Alanine Transaminase; Antiviral Agents; Carcinoma, Hepatocellular; DNA, Viral; Drug Resistance, Viral; Drug-Related Side Effects and Adverse Reactions; Female; Glomerular Filtration Rate; Guanine; Hepatitis B, Chronic; Humans; Incidence; Liver Neoplasms; Male; Middle Aged; Retrospective Studies; Telbivudine; Thymidine; Treatment Outcome | 2014 |
Serum interleukin-37 concentrations and HBeAg seroconversion in chronic HBV patients during telbivudine treatment.
Topics: Adult; Alanine Transaminase; Antiviral Agents; Coinfection; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatitis C, Chronic; Humans; Interleukin-1; Interleukin-10; Interleukin-2; Male; Middle Aged; Telbivudine; Thymidine; Young Adult | 2013 |
Circulating chemokine (C-X-C Motif) receptor 5(+) CD4(+) T cells benefit hepatitis B e antigen seroconversion through IL-21 in patients with chronic hepatitis B virus infection.
Topics: Adolescent; Adult; Antibodies, Viral; Antiviral Agents; Biomarkers; CD4-Positive T-Lymphocytes; Cells, Cultured; Cross-Sectional Studies; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; In Vitro Techniques; Interleukins; Longitudinal Studies; Male; Middle Aged; Phenotype; Receptors, CXCR5; Recombinant Proteins; Telbivudine; Thymidine; Young Adult | 2013 |
Serum hepatitis B surface antigen kinetics in severe reactivation of hepatitis B e antigen negative chronic hepatitis B patients receiving nucleoside/nucleotide analogues.
Topics: Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Nucleic Acid Synthesis Inhibitors; Recurrence; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine; Viral Load; Young Adult | 2013 |
Serum HBV DNA level at week 12 is superior to viral response at week 24 in predicting long-term treatment outcome of telbivudine for chronic hepatitis B patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Hepatitis B, Chronic; Humans; Male; Middle Aged; Telbivudine; Thymidine; Time Factors | 2013 |
Chemokine receptor 5 (CCR5) polymorphism in chronic hepatitis B patients treated with three different nucleos(t)ide analogues.
Topics: Adenine; Alanine Transaminase; Genotype; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Homozygote; Humans; India; Lamivudine; Liver Function Tests; Mutation; Nucleosides; Nucleotides; Organophosphonates; Pilot Projects; Polymorphism, Genetic; Receptors, CCR5; Telbivudine; Thymidine | 2013 |
[Clinical efficacy of telbivudine in retreatment and native treatment of chronic hepatitis B for 24 months].
Topics: Adult; Aged; Female; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2013 |
Dysphagia could be the first presenting symptom of telbivudine-induced myopathy.
Topics: Aged; Antiviral Agents; Deglutition Disorders; Female; Humans; Muscular Diseases; Telbivudine; Thymidine | 2013 |
On-treatment mortality predictors in chronic hepatitis B patients experiencing severe acute exacerbation: a prospective observational study.
Topics: Adult; Aged; alpha-Fetoproteins; Antiviral Agents; Bilirubin; Biomarkers; Disease Progression; Female; Glomerular Filtration Rate; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Predictive Value of Tests; Prognosis; Prospective Studies; Prothrombin Time; Survival Analysis; Telbivudine; Thymidine; Treatment Outcome | 2013 |
In vivo antiviral activity of telbivudine against HIV-1: a case report.
Topics: Acute Disease; Adenine; Adult; Antiviral Agents; Coinfection; Drug Therapy, Combination; Hepatitis B; Hepatitis B virus; HIV Infections; HIV-1; Humans; Immunocompromised Host; Male; Organophosphonates; Telbivudine; Thymidine; Treatment Outcome | 2013 |
Kinetics of Th17 cytokines during telbivudine therapy in patients with chronic hepatitis B.
Topics: Adult; Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Inflammation; Interleukin-17; Interleukin-22; Interleukin-23; Interleukins; Leukocyte Count; Leukocytes, Mononuclear; Male; Telbivudine; Th17 Cells; Thymidine | 2013 |
Real-world application of the roadmap model in chronic hepatitis B patients with telbivudine therapy.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Female; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Organophosphonates; Prospective Studies; Telbivudine; Thymidine; Treatment Outcome | 2013 |
Telbivudine treatment corrects HBV-induced epigenetic alterations in liver cells of patients with chronic hepatitis B.
Topics: Antiviral Agents; Case-Control Studies; Chromatin; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Gene Expression Regulation; Hep G2 Cells; Hepatitis B virus; Hepatitis B, Chronic; Histone-Lysine N-Methyltransferase; Histones; Humans; Inflammation; Liver; Liver Cirrhosis; Methylation; Polycomb Repressive Complex 2; Telbivudine; Thymidine | 2014 |
Potential benefit of telbivudine on renal function does not outweigh its high rate of antiviral drug resistance and other adverse effects.
Topics: Antiviral Agents; Female; Glomerular Filtration Rate; Hepatitis B, Chronic; Humans; Male; Renal Insufficiency, Chronic; Telbivudine; Thymidine | 2014 |
Durability of efficacy after telbivudine off-treatment in chronic hepatitis B patients.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Female; Follow-Up Studies; Hepatitis B, Chronic; Humans; Male; Middle Aged; Recurrence; Retrospective Studies; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2014 |
Antiviral therapy in patients with hepatitis B virus-related hepatocellular carcinoma: is it ready for universal application?
Topics: Antiviral Agents; Carcinoma, Hepatocellular; Hepatectomy; Hepatitis B, Chronic; Humans; Liver Neoplasms; Telbivudine; Thymidine; Treatment Outcome; Virus Activation | 2013 |
Long-term outcomes of chronic hepatitis B virus infection in the era of antiviral therapy in Korea.
Topics: Adult; Age Factors; Antiviral Agents; Carcinoma, Hepatocellular; Disease Progression; Female; Follow-Up Studies; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Republic of Korea; Telbivudine; Thymidine; Time Factors; Treatment Outcome | 2014 |
Telbivudine protects renal function in patients with chronic hepatitis B infection in conjunction with adefovir-based combination therapy.
Topics: Adenine; Adult; Aged; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Hepatitis B, Chronic; Humans; Kidney; Kidney Function Tests; Male; Middle Aged; Organophosphonates; Renal Insufficiency; Retrospective Studies; Telbivudine; Thymidine; Treatment Outcome; Viral Load | 2014 |
Reversible phospho-Smad3 signalling between tumour suppression and fibrocarcinogenesis in chronic hepatitis B infection.
Topics: Adult; Antiviral Agents; Carcinoma, Hepatocellular; Disease Progression; DNA, Viral; Female; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Humans; Immunohistochemistry; Lamivudine; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Phosphorylation; Protein Isoforms; Signal Transduction; Smad3 Protein; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2014 |
[Clinical observations of changes in serum creatine kinase during telbivudine treatment].
Topics: Adolescent; Adult; Aged; Creatine Kinase; Female; Hepatitis B, Chronic; Humans; Male; Middle Aged; Retrospective Studies; Telbivudine; Thymidine; Young Adult | 2013 |
TCRγδ(+)CD4(-)CD8(-) T cells suppress the CD8(+) T-cell response to hepatitis B virus peptides, and are associated with viral control in chronic hepatitis B.
Topics: Adult; Antiviral Agents; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cohort Studies; Cross-Sectional Studies; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; HIV Seropositivity; Humans; Liver; Lymphocyte Count; Male; Peptides; Receptors, Antigen, T-Cell, gamma-delta; Telbivudine; Thymidine; Young Adult | 2014 |
Comparison of telbivudine efficacy in treatment-naive patients with hepatitis B virus-related compensated and decompensated cirrhosis in 96 weeks.
Topics: Adult; Alanine Transaminase; Antiviral Agents; Biomarkers; Cholinesterases; Drug Resistance, Viral; Esophageal and Gastric Varices; Female; Hepatitis B; Humans; Liver; Liver Cirrhosis; Male; Middle Aged; Retrospective Studies; Serum Albumin; Serum Albumin, Human; Severity of Illness Index; Telbivudine; Thymidine; Time Factors; Treatment Outcome; Viral Load | 2014 |
Telbivudine decreases proportion of peripheral blood CD4+CD25+CD127low T cells in parallel with inhibiting hepatitis B virus DNA.
Topics: Adult; Antiviral Agents; Case-Control Studies; Female; Forkhead Transcription Factors; Gene Expression; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interleukin-2 Receptor alpha Subunit; Interleukin-7 Receptor alpha Subunit; Lymphocyte Count; Male; Middle Aged; T-Lymphocytes, Regulatory; Telbivudine; Thymidine; Viral Load | 2014 |
Successful withdrawal of antiviral treatment in kidney transplant recipients with chronic hepatitis B viral infection.
Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunosuppressive Agents; Kidney Transplantation; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Telbivudine; Thymidine; Time Factors; Virus Activation; Withholding Treatment | 2014 |
Ending vertical transmission of hepatitis B: the third trimester intervention.
Topics: Female; Hepatitis B, Chronic; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Male; Pregnancy; Pregnancy Complications, Infectious; Telbivudine; Thymidine | 2014 |
A possible role for NKT-like cells in patients with chronic hepatitis B during telbivudine treatment.
Topics: Adult; Antiviral Agents; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunophenotyping; Interleukin-17; Lymphocyte Count; Male; Middle Aged; Natural Killer T-Cells; T-Lymphocyte Subsets; Telbivudine; Thymidine; Treatment Outcome; Viral Load; Young Adult | 2014 |
An observational study to evaluate the safety and efficacy of telbivudine in adults with chronic hepatitis B.
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Hepatitis B Antibodies; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Prospective Studies; Telbivudine; Thymidine; Young Adult | 2014 |
Telbivudine therapy may shape CD4(+) T-cell response to prevent liver fibrosis in patients with chronic hepatitis B.
Topics: Adolescent; Adult; Antiviral Agents; Case-Control Studies; CD4-Positive T-Lymphocytes; Cells, Cultured; Coculture Techniques; Cytokines; DNA, Viral; Down-Regulation; Female; Hepatic Stellate Cells; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Liver Cirrhosis; Male; Middle Aged; Real-Time Polymerase Chain Reaction; Telbivudine; Thymidine; Transforming Growth Factor beta1; Up-Regulation; Young Adult | 2015 |
Efficacy of telbivudine compared with entecavir in hepatitis B virus-related cirrhosis: 2 year follow-up data.
Topics: Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug-Related Side Effects and Adverse Reactions; Female; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver Cirrhosis; Male; Middle Aged; Multivariate Analysis; Retrospective Studies; Telbivudine; Thymidine; Viral Load | 2015 |
Telbivudine plus tenofovir in combination therapy in patients with chronic hepatitis B infection--an Indian experience.
Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; India; Male; Middle Aged; Organophosphonates; Telbivudine; Tenofovir; Thymidine | 2013 |
Comparison of telbivudine versus lamivudine in interrupting perinatal transmission of hepatitis B virus.
Topics: Adult; Antiviral Agents; DNA, Viral; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Perinatal Care; Pregnancy; Pregnancy Complications, Infectious; Telbivudine; Thymidine; Treatment Outcome; Viral Load; Young Adult | 2014 |
Antiviral therapy of chronic hepatitis B.
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Carcinoma, Hepatocellular; Gene Products, pol; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver; Liver Cirrhosis; Liver Neoplasms; Organophosphonates; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Telbivudine; Tenofovir; Thymidine; Treatment Outcome; Virus Replication | 2014 |
Therapy of acute and fulminant hepatitis B.
Topics: Antiviral Agents; Guanine; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B Vaccines; Hepatitis B virus; Humans; Interferon-alpha; Lamivudine; Liver; Liver Failure, Acute; Liver Transplantation; Polyethylene Glycols; Recombinant Proteins; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine | 2014 |
Reduction of infectivity in chronic hepatitis B virus carriers among healthcare providers and pregnant women by antiviral therapy.
Topics: Adenine; Antiviral Agents; DNA, Viral; Female; Guanine; Health Personnel; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Infectious Disease Transmission, Professional-to-Patient; Infectious Disease Transmission, Vertical; Lamivudine; Organophosphonates; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Viral Load; Viremia | 2014 |
Mechanisms of hepatitis B virus resistance development.
Topics: Adenine; Amino Acid Substitution; Antiviral Agents; Deoxycytidine; Drug Resistance, Multiple, Viral; Emtricitabine; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Telbivudine; Tenofovir; Thymidine; Virus Replication | 2014 |
Hepatitis B virus drug resistance tools: one sequence, two predictions.
Topics: Adenine; Antiviral Agents; Base Sequence; Drug Resistance, Multiple, Viral; Genotype; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immune Evasion; Lamivudine; Microbial Sensitivity Tests; Organophosphonates; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Sequence Analysis, DNA; Telbivudine; Tenofovir; Thymidine | 2014 |
Antiviral efficacy analysis of telbivudine concurrent with the first cycle of chemotherapy in HBsAg-positive lymphoma patients.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antiviral Agents; Female; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Immunocompromised Host; Lymphoma; Male; Middle Aged; Retrospective Studies; Telbivudine; Thymidine; Treatment Outcome; Virus Activation; Young Adult | 2014 |
Lamivudine/telbivudine-associated neuromyopathy: neurogenic damage, mitochondrial dysfunction and mitochondrial DNA depletion.
Topics: Adult; Aged, 80 and over; Antiviral Agents; Biopsy; DNA, Mitochondrial; Female; Hepatitis B; Humans; Lamivudine; Male; Microscopy, Electron; Middle Aged; Mitochondria, Muscle; Muscle, Skeletal; Muscular Diseases; Peripheral Nerves; Peripheral Nervous System Diseases; Predictive Value of Tests; Real-Time Polymerase Chain Reaction; Retrospective Studies; Telbivudine; Thymidine; Young Adult | 2014 |
[Predictive value of HBeAg levels in telbivudine-treated chronic hepatitis B patients].
Topics: Adolescent; Adult; Female; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Retrospective Studies; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2014 |
[Retrospective analysis of the efficacy and safety of anti-hepatitis B virus drugs taken during pregnancy in women from the Guangdong Province].
Topics: Adenine; Antiviral Agents; Female; Guanine; Hepatitis B; Hepatitis B virus; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Male; Mothers; Organophosphonates; Pregnancy; Retrospective Studies; Telbivudine; Thymidine; Time Factors | 2014 |
Telbivudine prophylaxis for hepatitis B virus recurrence after liver transplantation improves renal function.
Topics: Adult; Antiviral Agents; Creatinine; Female; Hepatitis B, Chronic; Humans; Lamivudine; Liver Transplantation; Male; Middle Aged; Recurrence; Telbivudine; Thymidine | 2014 |
The incidence of hepatocellular carcinoma is reduced in patients with chronic hepatitis B on long-term nucleos(t)ide analogue therapy.
Topics: Adenine; Adult; Antiviral Agents; Canada; Carcinoma, Hepatocellular; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Incidence; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Nucleosides; Organophosphonates; Retrospective Studies; Risk Factors; Telbivudine; Tenofovir; Thymidine | 2014 |
Telbivudine is associated with improvement of renal function in patients transplanted for HBV liver disease.
Topics: Adult; Aged; Antiviral Agents; Chemoprevention; DNA, Viral; Female; Glomerular Filtration Rate; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Kidney; Kidney Function Tests; Liver Cirrhosis; Liver Transplantation; Male; Middle Aged; Prospective Studies; Telbivudine; Thymidine; Young Adult | 2015 |
Effect of Peg-interferon α-2a combined with Adefovir in HBV postpartum women with normal levels of ALT and high levels of HBV DNA.
Topics: Adenine; Adult; Antiviral Agents; DNA, Viral; Drug Therapy, Combination; Female; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Organophosphonates; Polyethylene Glycols; Postpartum Period; Pregnancy; Prospective Studies; Recombinant Proteins; Telbivudine; Thymidine; Treatment Outcome | 2015 |
Growth and development of children prenatally exposed to telbivudine administered for the treatment of chronic hepatitis B in their mothers.
Topics: Adult; Ankyloglossia; Antiviral Agents; Body Mass Index; Body Weight; Child Development; China; Delivery, Obstetric; Female; Hepatitis B Vaccines; Hepatitis B, Chronic; Humans; Infant; Infectious Disease Transmission, Vertical; Male; Maternal-Fetal Exchange; Mouth Abnormalities; Pregnancy; Pregnancy Complications, Infectious; Prenatal Exposure Delayed Effects; Reference Values; Telbivudine; Thymidine | 2015 |
[Promotion of HBeAg seroconversion/loss in patients with chronic hepatitis B following the switch from nucleoside drugs to telbivudine and adefovir].
Topics: Adenine; Drug Combinations; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Nucleic Acid Synthesis Inhibitors; Nucleosides; Organophosphonates; Telbivudine; Thymidine | 2014 |
[Effect of human concentration nucleoside transporters 1 and multi-drug resistance protein 4 gene polymorphism on response of chronic hepatitis B to nucleoside analogues treatment].
Topics: Antiviral Agents; Drug Resistance, Multiple, Viral; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Membrane Transport Proteins; Multidrug Resistance-Associated Proteins; Polymorphism, Single Nucleotide; Telbivudine; Thymidine | 2014 |
Is there an association of hepatitis B virus infection with minimal change disease of nephrotic syndrome? A clinical observational report.
Topics: Adult; Antiviral Agents; Biopsy; Drug Monitoring; Drug Therapy, Combination; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunosuppressive Agents; Kidney Function Tests; Kidney Glomerulus; Lamivudine; Male; Methylprednisolone; Nephrosis, Lipoid; Telbivudine; Thymidine; Treatment Outcome | 2015 |
Efficacy and safety of telbivudine treatment: an open-label, prospective study in pregnant women for the prevention of perinatal transmission of hepatitis B virus infection.
Topics: Adult; Antiviral Agents; Case-Control Studies; China; DNA, Viral; Female; Hepatitis B; Hepatitis B Surface Antigens; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Longitudinal Studies; Male; Pregnancy; Prospective Studies; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2015 |
The predictive value of early indicators for HBeAg seroconversion in HBeAg-positive chronic hepatitis B patients with Telbivudine treatment for 104 weeks.
Topics: Adult; Antiviral Agents; Female; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Prognosis; ROC Curve; Telbivudine; Thymidine; Time Factors; Treatment Outcome; Young Adult | 2015 |
Tenofovir rescue therapy in pregnant females with chronic hepatitis B.
Topics: Adenine; Adult; Antiviral Agents; Apgar Score; Biomarkers; Birth Weight; China; DNA, Viral; Drug Resistance, Viral; Drug Substitution; Female; Genotype; Hepatitis B Vaccines; Hepatitis B virus; Hepatitis B, Chronic; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Lamivudine; Live Birth; Male; Middle Aged; Mutation; Organophosphonates; Pregnancy; Pregnancy Complications, Infectious; Retrospective Studies; Telbivudine; Tenofovir; Thymidine; Time Factors; Treatment Outcome; Vaccination; Viral Load; Young Adult | 2015 |
[Clinical observation of telbivudine's antiviral efficacy and protection against mother-to-infant transmission of chronic hepatitis B during the first trimester of pregnancy].
Topics: Antiviral Agents; DNA, Viral; Female; Hepatitis A Vaccines; Hepatitis B e Antigens; Hepatitis B Vaccines; Hepatitis B virus; Hepatitis B, Chronic; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Mother-Child Relations; Mutation; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, First; Telbivudine; Thymidine; Vaccines, Combined | 2015 |
[Nucleoside analogues for acute-on-chronic liver failure associated with hepatitis B virus infection: a 24-month survival analysis].
Topics: Acute-On-Chronic Liver Failure; Antiviral Agents; Cohort Studies; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Prospective Studies; Survival Analysis; Survival Rate; Telbivudine; Thymidine; Time Factors | 2015 |
Aberrant expression and dysfunction of TLR2 and its soluble form in chronic HBV infection and its regulation by antiviral therapy.
Topics: Adolescent; Adult; Antiviral Agents; Cross-Sectional Studies; Female; Gene Expression Profiling; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Interleukin-6; Male; Middle Aged; Polyethylene Glycols; Recombinant Proteins; Telbivudine; Thymidine; Toll-Like Receptor 2; Tumor Necrosis Factor-alpha; Young Adult | 2015 |
Telbivudine in liver transplant recipients: Renal protection does not overcome the risk of polyneuropathy and myopathy.
Topics: Aged; Antiviral Agents; Diabetes Mellitus; Drug Substitution; End Stage Liver Disease; Female; Glomerular Filtration Rate; Hepatitis B; Humans; Incidence; Kaplan-Meier Estimate; Kidney; Lamivudine; Liver Transplantation; Male; Middle Aged; Muscular Diseases; Polyneuropathies; Proportional Hazards Models; Prospective Studies; Recovery of Function; Recurrence; Renal Insufficiency, Chronic; Risk Factors; Telbivudine; Thymidine; Time Factors; Treatment Outcome; Turkey | 2015 |
Efficacy of telbivudine in the treatment of chronic hepatitis b and liver cirrhosis and its effect on immunological responses.
Topics: Adult; Aged; Antiviral Agents; Female; Hepatitis B, Chronic; Humans; Liver Cirrhosis; Male; Middle Aged; Telbivudine; Thymidine | 2015 |
Impact of nucleos(t)ide analogue combination therapy on the estimated glomerular filtration rate in patients with chronic hepatitis B.
Topics: Adenine; Adult; Aged; Antiviral Agents; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Nucleosides; Nucleotides; Organophosphonates; Retrospective Studies; Telbivudine; Thymidine | 2015 |
[Predictive value of telbivudine in preventing mother-to-infant transmission of hepatitis B virus in pregnant women with high viremia].
Topics: Female; Hepatitis B Surface Antigens; Hepatitis B Vaccines; Hepatitis B virus; Humans; Immunoglobulins; Infant, Newborn; Infectious Disease Transmission, Vertical; Mothers; Pregnancy; Pregnancy Complications, Infectious; Telbivudine; Thymidine; Viremia | 2015 |
Comparison of the Effects of Telbivudine and Entecavir Treatment on Estimated Glomerular Filtration Rate in Patients with Chronic Hepatitis B.
Topics: Adult; Antiviral Agents; Diabetes Complications; Diabetes Mellitus; Drug Administration Schedule; Female; Fibrosis; Glomerular Filtration Rate; Guanine; Hepatitis B, Chronic; Humans; Hypertension; Linear Models; Male; Middle Aged; Telbivudine; Thymidine; Time Factors; Treatment Outcome | 2015 |
Prevalence and types of drug-resistant variants in Chinese patients with acute hepatitis B.
Topics: Adenine; Adult; Antiviral Agents; China; DNA, Viral; Drug Resistance, Viral; Female; Genetic Variation; Guanine; Hepatitis B; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation, Missense; Organophosphonates; Prevalence; RNA-Directed DNA Polymerase; Telbivudine; Thymidine; Time Factors; Young Adult | 2015 |
UPLC-MS/MS method for the simultaneous quantification of anti-HBV nucleos(t)ides analogs: Entecavir, lamivudine, telbivudine and tenofovir in plasma of HBV infected patients.
Topics: Antiviral Agents; Calibration; Chemistry Techniques, Analytical; Chromatography; Chromatography, High Pressure Liquid; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Limit of Detection; Nucleosides; Reproducibility of Results; Tandem Mass Spectrometry; Telbivudine; Tenofovir; Thymidine | 2015 |
Comparison of renal safety and efficacy of telbivudine, entecavir and tenofovir treatment in chronic hepatitis B patients: real world experience.
Topics: Adult; Aged; Aged, 80 and over; Antiviral Agents; Drug-Related Side Effects and Adverse Reactions; Female; Glomerular Filtration Rate; Guanine; Hepatitis B, Chronic; Humans; Kidney Diseases; Kidney Function Tests; Male; Middle Aged; Retrospective Studies; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2016 |
[Efficacy and safety of telbivudine alone and combined with adefovir for the treatment of nucleos(t)ide-naive chronic hepatitis B in patients with high-level hepatitis B virus load].
Topics: Adenine; Alanine Transaminase; Drug Therapy, Combination; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Organophosphonates; Retrospective Studies; Telbivudine; Thymidine; Treatment Outcome; Viral Load | 2015 |
[Prevention of mother to child transmission of hepatitis B].
Topics: Adult; Antiviral Agents; Female; Hepatitis B Surface Antigens; Hepatitis B Vaccines; Hepatitis B, Chronic; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Pregnancy; Pregnancy Complications, Infectious; Retrospective Studies; Telbivudine; Tenofovir; Thymidine; Viral Load; Young Adult | 2015 |
[Influence of monotherapy with telbivudine or entecavir on renal function in patients with chronic hepatitis B].
Topics: Alanine Transaminase; Antiviral Agents; Creatinine; Guanine; Hepatitis B, Chronic; Humans; Kidney; Kidney Function Tests; Telbivudine; Thymidine | 2015 |
Ten-year follow-up of hepatitis B relapse after cessation of lamivudine or telbivudine treatment in chronic hepatitis B patients.
Topics: Adolescent; Adult; Antiviral Agents; DNA, Viral; Feasibility Studies; Female; Follow-Up Studies; Hepacivirus; Hepatitis B Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Recurrence; Retrospective Studies; Telbivudine; Thymidine; Young Adult | 2015 |
A novel RRM2B gene variant associated with Telbivudine-induced mitochondrial myopathy.
Topics: Aged; Antiviral Agents; Cell Cycle Proteins; Female; Hepatitis B, Chronic; Humans; Liver Transplantation; Mitochondrial Myopathies; Mutation; Ribonucleotide Reductases; Telbivudine; Thymidine | 2015 |
Efficacy and resistance to telbivudine treatment in chronic hepatitis B patients with favorable predictors: a multicenter study in Taiwan.
Topics: Adult; Aged; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Prospective Studies; Retrospective Studies; Taiwan; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2016 |
Long-term follow-up of HBsAg-positive patients in Germany.
Topics: Adenine; Adult; Age Factors; Antiviral Agents; Carcinoma, Hepatocellular; DNA, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; Germany; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Male; Mass Screening; Middle Aged; Organophosphonates; Prognosis; Prospective Studies; Retrospective Studies; Telbivudine; Tenofovir; Thymidine; Time Factors; Turkey | 2016 |
[The safety of telbivudine in preventing mother-to-infant transmission of hepatitis B virus in pregnant women after discontinuation].
Topics: Adult; Antiviral Agents; DNA, Viral; Female; Hepatitis B Vaccines; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunoglobulins; Infant, Newborn; Infectious Disease Transmission, Vertical; Mothers; Pregnancy; Pregnancy Complications, Infectious; Telbivudine; Thymidine; Young Adult | 2015 |
Use of telbivudine in kidney transplant recipients with chronic hepatitis B virus infection: A preliminary experience.
Topics: Allografts; Antiviral Agents; Biomarkers; DNA, Viral; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Kidney Transplantation; Liver Function Tests; Pilot Projects; Telbivudine; Thymidine; Time Factors; Treatment Outcome; Viral Load | 2016 |
A comparison of telbivudine and entecavir in the treatment of hepatitis B e antigen-positive patients: a prospective cohort study in China.
Topics: Adult; Aged; Antiviral Agents; Biomarkers; China; Female; Follow-Up Studies; Guanine; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Telbivudine; Thymidine; Treatment Outcome; Viral Load; Young Adult | 2016 |
Cumulative incidence and risk factors of creatine kinase elevation associated with telbivudine.
Topics: Adult; Aged; Antiviral Agents; Creatine Kinase; Female; Glomerular Filtration Rate; Hepatitis B, Chronic; Humans; Incidence; Male; Middle Aged; Risk Factors; Sex Factors; Telbivudine; Thymidine; Young Adult | 2016 |
Comparison of efficacy and renal safety of telbivudine and entecavir in treatment-naive elderly patients with chronic hepatitis B.
Topics: Age Factors; Aged; Biomarkers; DNA, Viral; Drug Resistance, Neoplasm; Female; Glomerular Filtration Rate; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Kidney; Liver Function Tests; Male; Middle Aged; Recovery of Function; Retrospective Studies; Risk Factors; Telbivudine; Thymidine; Time Factors; Treatment Outcome; Viral Load | 2016 |
Comprehensive analysis of hospital-based prospective cohort reveals the unique effectiveness and safety for nucleos(t)ide analogues in HBV patients.
Topics: Adenine; Adult; Antiviral Agents; Female; Guanine; Hepatitis B, Chronic; Hospitalization; Humans; Lamivudine; Male; Organophosphonates; Prospective Studies; Telbivudine; Thymidine; Treatment Outcome | 2016 |
Composition and Interactions of Hepatitis B Virus Quasispecies Defined the Virological Response During Telbivudine Therapy.
Topics: Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; High-Throughput Nucleotide Sequencing; Humans; Male; Middle Aged; Mutation; Phylogeny; Remission Induction; RNA-Directed DNA Polymerase; Sequence Analysis, DNA; Telbivudine; Thymidine; Young Adult | 2015 |
Nephrotoxicity caused by oral antiviral agents in patients with chronic hepatitis B treated in a hospital for tropical diseases in Thailand.
Topics: Adenine; Adult; Antiviral Agents; Creatinine; Female; Follow-Up Studies; Guanine; Hepatitis B, Chronic; Hospitals; Humans; Incidence; Kidney Diseases; Lamivudine; Male; Middle Aged; Nephrons; Organophosphonates; Proportional Hazards Models; Retrospective Studies; Risk Assessment; Risk Factors; Telbivudine; Tenofovir; Thailand; Thymidine; Tropical Medicine | 2015 |
[Efficacy of combination antiviral therapy following childbirth in pregnant HBV carriers receiving telbivudine for prevention of mother-to-child transmission].
Topics: Adenine; Alanine Transaminase; Antiviral Agents; Carrier State; DNA, Viral; Drug Therapy, Combination; Female; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Infectious Disease Transmission, Vertical; Interferon-alpha; Organophosphonates; Polyethylene Glycols; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Third; Recombinant Proteins; Telbivudine; Thymidine | 2015 |
Off-treatment efficacy of 3-year nucleos(t)ide analogues in chronic hepatitis B patients.
Topics: Adenine; Adult; Alanine Transaminase; Antiviral Agents; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2016 |
COLD-PCR for early detection of hepatitis B virus antiviral drug resistance mutations.
Topics: Antiviral Agents; Cold Temperature; Drug Resistance, Viral; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Mutation; Polymerase Chain Reaction; Sensitivity and Specificity; Telbivudine; Thymidine | 2015 |
[Drug-resistant mutations in hepatitis B virus found in chronic HBV carriers using PCR sequencing technology].
Topics: Adenine; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Mutation; Organophosphonates; Polymerase Chain Reaction; Telbivudine; Tenofovir; Thymidine | 2016 |
Efficacy and safety of tenofovir, entecavir, and telbivudine for chronic hepatitis B in heart transplant recipients.
Topics: Adult; Aged; Antiviral Agents; Cohort Studies; DNA, Viral; Female; Follow-Up Studies; Guanine; Heart Transplantation; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Middle Aged; Prospective Studies; Telbivudine; Tenofovir; Thymidine; Treatment Outcome; Viremia | 2016 |
[Effect of IL-28B polymorphisms on the natural course of HBV infection].
Topics: Adult; Antiviral Agents; Carrier State; Female; Guanine; Hepatitis B, Chronic; Humans; Interferons; Interleukins; Lamivudine; Male; Middle Aged; Polymorphism, Genetic; Prospective Studies; Real-Time Polymerase Chain Reaction; Telbivudine; Tenofovir; Thymidine; Turkey | 2016 |
Comparison of clinical efficacy and renal safety of telbivudine and entecavir in chronic hepatitis B patients receiving cytotoxic chemotherapy.
Topics: Aged; Antineoplastic Agents; Antiviral Agents; DNA, Viral; Female; Glomerular Filtration Rate; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Kidney; Male; Middle Aged; Neoplasms; Retrospective Studies; Secondary Prevention; Telbivudine; Thymidine; Virus Activation | 2016 |
Telbivudine versus lamivudine and entecavir for treatment-naïve decompensated hepatitis B virus-related cirrhosis.
Topics: Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug-Related Side Effects and Adverse Reactions; Female; Guanine; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Lamivudine; Liver Cirrhosis; Male; Middle Aged; Prospective Studies; Retrospective Studies; Seroconversion; Telbivudine; Thymidine; Treatment Outcome; Viral Load | 2017 |
Hepatic flare after telbivudine withdrawal and efficacy of postpartum antiviral therapy for pregnancies with chronic hepatitis B virus.
Topics: Adult; Alanine Transaminase; Antiviral Agents; Drug Administration Schedule; Female; Follow-Up Studies; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Infectious Disease Transmission, Vertical; Postpartum Period; Pregnancy; Pregnancy Complications, Infectious; Telbivudine; Thymidine; Young Adult | 2017 |
Elevated serum interleukin-38 level at baseline predicts virological response in telbivudine-treated patients with chronic hepatitis B.
Topics: Administration, Oral; Adult; Antiviral Agents; Biomarkers; Case-Control Studies; DNA, Viral; Drug Administration Schedule; Enzyme-Linked Immunosorbent Assay; Female; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interleukins; Male; Sustained Virologic Response; Telbivudine; Th1-Th2 Balance; Thymidine; Time Factors; Up-Regulation; Viral Load; Young Adult | 2016 |
Cost-effectiveness analysis of tenofovir disoproxil fumarate for treatment of chronic hepatitis B in China.
Topics: Adenine; Antiviral Agents; Cost-Benefit Analysis; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Male; Markov Chains; Organophosphonates; Quality-Adjusted Life Years; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2016 |
Comparative effectiveness of nucleos(t)ide analogues in chronic hepatitis B patients undergoing cytotoxic chemotherapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antiviral Agents; Cytotoxins; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Neoplasms; Retrospective Studies; Telbivudine; Tenofovir; Thymidine; Virus Activation; Young Adult | 2016 |
[Telbivudine for prevention of perinatal transmission in pregnant women infected with hepatitis B virus in immune-tolerant phase: a study of efficacy and safety of drug withdrawal].
Topics: Antiviral Agents; Female; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Humans; Infant; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; Telbivudine; Thymidine; Treatment Outcome; Viremia | 2016 |
[HBsAg clearance rate in patients with HBeAg-positive chronic hepatitis B: a comparative effect analysis based on the real world].
Topics: Adenine; Antiviral Agents; Guanine; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Organophosphonates; Retrospective Studies; Telbivudine; Thymidine; Treatment Outcome | 2016 |
Small surface antigen variants of HBV associated with responses to telbivudine treatment in chronic hepatitis B patients.
Topics: Adult; Antiviral Agents; DNA Mutational Analysis; DNA, Viral; Drug Resistance, Viral; Female; Genetic Variation; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Mutation; Sustained Virologic Response; Telbivudine; Thymidine; Time Factors; Young Adult | 2017 |
Clinicopathological Features of Telbivudine-Associated Myopathy.
Topics: Aged; Female; Humans; Male; Middle Aged; Muscular Diseases; Telbivudine; Thymidine | 2016 |
Reduction of covalently closed circular DNA with long-term nucleos(t)ide analogue treatment in chronic hepatitis B.
Topics: Adenine; Antiviral Agents; Biopsy; DNA, Circular; DNA, Viral; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Liver; Male; Middle Aged; Nucleosides; Organophosphonates; Outcome Assessment, Health Care; Telbivudine; Thymidine; Time; Virus Replication | 2017 |
Long-term outcomes of hepatitis B virus-related cirrhosis treated with nucleos(t)ide analogs.
Topics: Adult; Aged; Antiviral Agents; Carcinoma, Hepatocellular; Female; Guanine; Hepatitis B, Chronic; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Proportional Hazards Models; Renal Insufficiency, Chronic; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2017 |
Telbivudine treatment of hepatitis B virus-infected pregnant women at different gestational stages for the prevention of mother-to-child transmission: Outcomes of telbivudine treatment during pregnancy.
Topics: Adult; Antiviral Agents; Cohort Studies; Drug Administration Schedule; Female; Hepatitis B, Chronic; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, First; Pregnancy Trimester, Second; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2016 |
Comparison of the Efficacies and Safety of Combined Therapy between Telbivudine Plus Adefovir and Lamivudine Plus Adefovir in Patients with Hepatitis B Virus Infection in Real-World Practice.
Topics: Adenine; Adult; Biomarkers; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Retrospective Studies; Telbivudine; Thymidine; Treatment Outcome | 2016 |
DNMT1 modulation in chronic hepatitis B patients and hypothetic influence on mitochondrial DNA methylation status during long-term nucleo(t)side analogs therapy.
Topics: Adenine; Aged; Antiviral Agents; Cross-Sectional Studies; Cytosine; DNA (Cytosine-5-)-Methyltransferase 1; DNA Methylation; DNA, Mitochondrial; Female; Guanine; Hepatitis B, Chronic; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Nucleosides; Organophosphonates; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Telbivudine; Thymidine | 2017 |
A Follow-Up Study on the Renal Protective Efficacy of Telbivudine for Hepatitis B Virus-Infected Taiwanese Patients After Living Donor Liver Transplant.
Topics: Adult; Aged; Antiviral Agents; Biomarkers; Creatinine; Cross-Sectional Studies; End Stage Liver Disease; Female; Follow-Up Studies; Glomerular Filtration Rate; Guanine; Hepatitis B; Hepatitis B virus; Humans; Kidney; Liver Transplantation; Living Donors; Male; Middle Aged; Recovery of Function; Retrospective Studies; Risk Factors; Taiwan; Telbivudine; Thymidine; Time Factors; Treatment Outcome; Virus Activation | 2017 |
Long-term safety and efficacy of telbivudine in infants born to mothers treated during the second or third trimesters of pregnancy.
Topics: Adult; Antiviral Agents; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Female; Hepatitis B, Chronic; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Male; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Prospective Studies; Telbivudine; Thymidine; Treatment Outcome; Young Adult | 2017 |
Anti-HBV drugs suppress the growth of HBV-related hepatoma cells via down-regulation of hepatitis B virus X protein.
Topics: Animals; Antiviral Agents; Carcinoma, Hepatocellular; Cell Proliferation; DNA Replication; DNA, Viral; Dose-Response Relationship, Drug; Down-Regulation; Drug Therapy, Combination; Guanine; Hep G2 Cells; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Liver Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Mice, Transgenic; Recombinant Proteins; RNA Interference; Telbivudine; Thymidine; Time Factors; Trans-Activators; Transfection; Tumor Burden; Viral Regulatory and Accessory Proteins; Virus Replication; Xenograft Model Antitumor Assays | 2017 |
Telbivudine attenuates gentamicin-induced kidney injury in rats.
Topics: Acute Kidney Injury; Animals; Cystatin C; Gentamicins; Glomerular Filtration Rate; Hepatitis B, Chronic; Kidney; Lamivudine; Male; Pilot Projects; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Telbivudine; Thymidine | 2017 |
[Rhabdomyolysis associated with telbivudin therapy: report of a case].
Topics: Adult; Antiviral Agents; Humans; Male; Rhabdomyolysis; Telbivudine; Thymidine | 2017 |
Effectiveness of entecavir or telbivudine therapy in patients with chronic hepatitis B virus infection pre-treated with interferon compared with de novo therapy with entecavir and telbivudine.
Topics: Adult; Antiviral Agents; Drug Resistance, Viral; Female; Follow-Up Studies; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferons; Logistic Models; Male; Multivariate Analysis; Retreatment; ROC Curve; Telbivudine; Thymidine; Treatment Outcome; Viral Load | 2017 |
Relationship of Treg/Th17 balance with HBeAg change in HBeAg-positive chronic hepatitis B patients receiving telbivudine antiviral treatment: A longitudinal observational study.
Topics: Adult; Antiviral Agents; Biomarkers; Female; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Interleukin-17; Longitudinal Studies; Male; Middle Aged; Seroconversion; T-Lymphocytes, Regulatory; Telbivudine; Th17 Cells; Thymidine; Transforming Growth Factor beta1; Treatment Outcome; Young Adult | 2017 |
Safety and efficacy of telbivudine for chronic hepatitis B during the entire pregnancy: Long-term follow-up.
Topics: Antiviral Agents; Child Development; Child, Preschool; Female; Follow-Up Studies; Hepatitis B, Chronic; Humans; Infant; Infant, Newborn; Male; Pregnancy; Pregnancy Complications, Infectious; Telbivudine; Thymidine; Time Factors; Treatment Outcome | 2017 |
Improvement of telbivudine on renal function and massive proteinuria: A case report.
Topics: Antiviral Agents; Biomarkers; Hepatitis B, Chronic; Humans; Kidney Function Tests; Liver Cirrhosis; Male; Middle Aged; Proteinuria; Telbivudine; Thymidine; Tomography, X-Ray Computed; Treatment Outcome; Viral Load | 2017 |
Comparing Efficacy of Lamivudine, Adefovir Dipivoxil, Telbivudine, and Entecavir in Treating Nucleoside Analogues Naïve for HBeAg-Negative Hepatitis B with Medium Hepatitis B Virus (HBV) DNA Levels.
Topics: Adenine; Adult; Alanine Transaminase; DNA, Viral; Female; Follow-Up Studies; Guanine; Hepatitis B; Hepatitis B e Antigens; Humans; Lamivudine; Male; Multivariate Analysis; Nucleosides; Organophosphonates; Proportional Hazards Models; Telbivudine; Thymidine | 2017 |
Determination of telbivudine in the plasma of chronic hepatitis B patients in long-term treatment by high-performance liquid chromatographic-tandem mass spectrometry.
Topics: Adult; Antiviral Agents; Chromatography, High Pressure Liquid; Creatine Kinase; Drug Monitoring; Female; Hepatitis B, Chronic; Humans; Linear Models; Male; Middle Aged; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Telbivudine; Thymidine; Young Adult | 2018 |
Telbivudine attenuates UUO-induced renal fibrosis via TGF-β/Smad and NF-κB signaling.
Topics: Animals; Antiviral Agents; Disease Models, Animal; Fibrosis; Hepatitis B virus; Humans; Inflammation Mediators; Kidney; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad Proteins; Telbivudine; Thymidine; Transforming Growth Factor beta; Ureter; Ureteral Obstruction | 2018 |
Safety and efficacy of lamivudine or telbivudine started in early pregnancy for mothers with active chronic hepatitis B.
Topics: Adult; Antiviral Agents; Case-Control Studies; DNA, Viral; Female; Hepatitis B e Antigens; Hepatitis B Vaccines; Hepatitis B, Chronic; Humans; Immunization, Passive; Immunoglobulins; Infant; Infectious Disease Transmission, Vertical; Lamivudine; Patient Safety; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Pregnancy Trimester, First; Retrospective Studies; Telbivudine; Thymidine; Treatment Outcome; Viral Load | 2018 |
Motor development delay in offspring is associated with prenatal telbivudine exposure.
Topics: Adult; Antiviral Agents; Developmental Disabilities; DNA, Viral; Female; Hepatitis B virus; Hepatitis B, Chronic; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Male; Pregnancy; Prenatal Exposure Delayed Effects; Prospective Studies; Telbivudine; Thymidine; Young Adult | 2018 |
Real World Experience of Telbivudine Versus Entecavir in Patients with Chronic Hepatitis B, Including Long-Term Outcomes after Treatment Modification.
Topics: Adult; Aged; Antiviral Agents; Female; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Incidence; Male; Middle Aged; Republic of Korea; Retrospective Studies; Telbivudine; Thymidine; Time Factors; Treatment Outcome | 2018 |
Prevention of mother-to-child transmission: the key of hepatitis B virus elimination.
Topics: Antiviral Agents; Female; Hepatitis B; Hepatitis B virus; Humans; Immunization Programs; Infant, Newborn; Infectious Disease Transmission, Vertical; Pregnancy; Preventive Health Services; Telbivudine; Thymidine; Time-to-Treatment | 2018 |
Case report: lactic acidosis and rhabdomyolysis during telbivudine and tenofovir treatment for chronic hepatitis B.
Topics: Acidosis, Lactic; Antiviral Agents; DNA Polymerase gamma; Drug Therapy, Combination; Hepatitis B, Chronic; Humans; Male; Middle Aged; Rhabdomyolysis; Telbivudine; Tenofovir; Thymidine | 2018 |
Trends in hepatitis B virus resistance to nucleoside/nucleotide analogues in North China from 2009-2016: A retrospective study.
Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Child; Child, Preschool; China; DNA, Viral; Drug Resistance, Viral; Female; Genotype; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Retrospective Studies; Telbivudine; Thymidine; Virus Activation; Virus Replication | 2018 |
Clinical-features analysis on 926 patients with virological breakthrough in chronic hepatitis B receiving nucleos(t)ide analogues.
Topics: Adenine; Adult; DNA, Viral; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Male; Medication Adherence; Organophosphonates; Reverse Transcriptase Inhibitors; Sustained Virologic Response; Telbivudine; Thymidine | 2018 |
Hepatitis B virus serosurvey and awareness of mother-to-child transmission among pregnant women in Shenyang, China: An observational study.
Topics: Adult; Antiviral Agents; China; Female; Health Knowledge, Attitudes, Practice; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Infectious Disease Transmission, Vertical; Middle Aged; Pregnancy; Pregnancy Complications, Infectious; Pregnant Women; Seroepidemiologic Studies; Telbivudine; Thymidine; Viral Load; Young Adult | 2018 |
Effectiveness of telbivudine antiviral treatment in patients with hepatitis B virus-associated glomerulonephritis: A 104-week pilot study.
Topics: Adult; Alanine Transaminase; Antiviral Agents; Aspartate Aminotransferases; DNA, Viral; Female; Glomerular Filtration Rate; Glomerulonephritis; Hepatitis B Antibodies; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Pilot Projects; Proteinuria; Remission Induction; Telbivudine; Thymidine; Viral Load; Young Adult | 2018 |
The use of tenofovir and telbivudine combination therapy for immune-tolerant chronic hepatitis B patients awaiting assisted reproduction.
Topics: Antiviral Agents; Hepatitis B, Chronic; Humans; Telbivudine; Tenofovir; Thymidine; Viral Load | 2019 |
[A case report of severe edema in both lower limbs of hepatitis B patients with normal renal function induced by telbivudine].
Topics: Antiviral Agents; DNA, Viral; Edema; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Humans; Lower Extremity; Nucleosides; Telbivudine; Thymidine; Treatment Outcome | 2019 |
Clinical and Immunological Factors Associated with Postpartum Hepatic Flares in Immune-Tolerant Pregnant Women with Hepatitis B Virus Infection Treated with Telbivudine.
Topics: Alanine Transaminase; Antiviral Agents; DNA, Viral; Female; Hepatitis B; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Immunologic Factors; Postpartum Period; Pregnancy; Pregnancy Complications, Infectious; Pregnant Women; Prospective Studies; Telbivudine; Thymidine | 2021 |
Efficacy and Long-term Safety of Telbivudine Usage During Second or Third Trimester in Hepatitis B Surface Antigen Positive Mothers With High Viral Load: A 10-year Prospective Study.
Topics: Antiviral Agents; DNA, Viral; Female; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Infectious Disease Transmission, Vertical; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Third; Prospective Studies; Telbivudine; Thymidine; Viral Load | 2023 |