thymidine has been researched along with sirolimus in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (50.00) | 18.2507 |
| 2000's | 10 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cooper, MH; Gregory, SH; Starzl, TE; Wing, EJ | 1 |
| Barkis, I; Degiannis, D; Hadjiyannaki-Koniavitou, K; Hornung, N; Raskova, J; Vareltzides, A | 1 |
| Blenis, J; Franklin, RA; Gelfand, EW; Lucas, JJ; Terada, N | 1 |
| Abraham, RT; Brunn, GJ; Morice, WG; Siekierka, JJ; Wiederrecht, G | 1 |
| Chong, AS; Finnegan, A; Foster, P; Gebel, H; Jiang, XL; Petraitis, EE; Sankary, HN; Williams, JW | 1 |
| Bittorf, T; Brock, J; Jaster, R; Klinken, SP | 1 |
| Garcia, B; Jones, N; Mann, D; Rozengurt, E; Seufferlein, T; Withers, DJ | 1 |
| Anderson, WH; Chung, T; Crilly, KS; Kiss, Z; Mukherjee, JJ | 1 |
| Crilly, KS; Kiss, Z; Tomono, M | 1 |
| Chambard, JC; Pouysségur, J; Viñals, F | 1 |
| Bell, A; Grunder, L; Sorisky, A | 1 |
| Cho, BY; Chung, HK; Chung, J; Han, JH; Hwang, ES; Hwang, JH; Kim, DW; Kim, H; Kim, JM; Ro, HK; Shong, M; Song, JH; Suh, JM | 1 |
| Brennan, P; Breslin, EM; Clement, M; Shore, AM; White, PC | 1 |
| Chouinard, M; Coleman, K; Czech, MP; Holik, J; Jiang, ZY; Leszyk, J; Patel, S; Zhou, QL | 1 |
| Erlichman, C; Goble, JM; James, CD; Lamont, JD; Mladek, AC; Rao, RD; Sarkaria, JN | 1 |
| Kwon, G; Liu, H; Marshall, CA; McDaniel, ML; Pappan, KL; Remedi, MS | 1 |
| Lock, HR; Robson, MG; Sacks, SH | 1 |
| Goldman, M; Rahmouni, S; Springael, C; Thomas, S; Vandamme, A; Vosters, O; Willems, F | 1 |
| Greutert, H; Grünenfelder, J; Jaschko, A; Joch, H; Kurz, DJ; Kuttler, B; Lüscher, TF; Matter, CM; Rozenberg, I; Tanner, FC; Wnendt, S; Zünd, G | 1 |
| Czernin, J; Hildebrandt, IJ; Phelps, ME; Su, H; Weber, WA; Wei, LH | 1 |
20 other study(ies) available for thymidine and sirolimus
| Article | Year |
|---|---|
Rapamycin but not FK506 inhibits the proliferation of mononuclear phagocytes induced by colony-stimulating factors.
Topics: Animals; Bone Marrow Cells; Cell Count; Cell Division; Colony-Stimulating Factors; Concanavalin A; Culture Media, Conditioned; Cyclosporine; Female; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Phagocytes; Polyenes; Sirolimus; Spleen; T-Lymphocytes; Tacrolimus; Tetrazolium Salts; Thiazoles; Thymidine; Tritium | 1994 |
Effect of rapamycin on the in vitro release of soluble interleukin-2 receptor by phytohemagglutinin, phorbol myristate acetate, and ionomycin-activated peripheral blood mononuclear cells.
Topics: Cells, Cultured; Cyclosporine; DNA; Humans; Immunosuppressive Agents; Ionomycin; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Polyenes; Receptors, Interleukin-2; Sirolimus; Tetradecanoylphorbol Acetate; Thymidine | 1995 |
Failure of rapamycin to block proliferation once resting cells have entered the cell cycle despite inactivation of p70 S6 kinase.
Topics: Amino Acid Sequence; Antibodies; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cell Division; Cell Line; DNA Replication; Enzyme Activation; Genes, fos; Genes, myc; Humans; Immunoassay; Immunosuppressive Agents; Interleukin-2; Kinetics; Molecular Sequence Data; Peptides; Phosphorylation; Polyenes; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Recombinant Proteins; Ribosomal Protein S6 Kinases; Sirolimus; T-Lymphocytes; Thymidine; Time Factors; Transcription, Genetic; Tritium | 1993 |
Rapamycin-induced inhibition of p34cdc2 kinase activation is associated with G1/S-phase growth arrest in T lymphocytes.
Topics: Animals; CDC2 Protein Kinase; Cell Division; Cell Line; Cell Survival; Cytotoxicity, Immunologic; DNA Replication; Enzyme Activation; G1 Phase; Immunosuppressive Agents; Interleukin-2; Kinetics; Mice; Polyenes; S Phase; Sirolimus; T-Lymphocytes, Cytotoxic; Thymidine | 1993 |
Leflunomide, a novel immunomodulatory agent: in vitro analyses of the mechanism of immunosuppression.
Topics: Cells, Cultured; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Isoxazoles; Leflunomide; Lymphocyte Activation; Polyenes; Sirolimus; T-Lymphocytes; Thymidine; Tritium | 1993 |
Inhibition of proliferation but not erythroid differentiation of J2E cells by rapamycin.
Topics: Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Drug Synergism; Erythrocytes; Erythropoietin; Humans; Immunosuppressive Agents; Polyenes; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; Sirolimus; Thymidine | 1996 |
Rapamycin dissociates p70(S6K) activation from DNA synthesis stimulated by bombesin and insulin in Swiss 3T3 cells.
Topics: 3T3 Cells; Animals; Bombesin; Cell Cycle Proteins; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; DNA Replication; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Immunosuppressive Agents; Insulin; Mice; Microtubule-Associated Proteins; Oncogene Proteins; Phosphorylation; Polyenes; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; Sirolimus; Thymidine; Time Factors; Tumor Suppressor Proteins | 1997 |
ATP-dependent choline phosphate-induced mitogenesis in fibroblasts involves activation of pp70 S6 kinase and phosphatidylinositol 3'-kinase through an extracellular site. Synergistic mitogenic effects of choline phosphate and sphingosine 1-phosphate.
Topics: 3T3 Cells; Adenosine Triphosphate; Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; DNA; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Harvey murine sarcoma virus; Immunosuppressive Agents; Insulin; Kinetics; Lysophospholipids; Mice; Models, Biological; Phosphatidylinositol 3-Kinases; Phospholipases A; Phosphorylcholine; Phosphotransferases (Alcohol Group Acceptor); Polyenes; Protein Serine-Threonine Kinases; Recombinant Proteins; Ribosomal Protein S6 Kinases; Sirolimus; Sphingosine; Thymidine; Transfection; Wortmannin | 1997 |
Bombesin and zinc enhance the synergistic mitogenic effects of insulin and phosphocholine by a MAP kinase-dependent mechanism in Swiss 3T3 cells.
Topics: 3T3 Cells; Androstadienes; Animals; Bombesin; DNA Replication; Drug Synergism; Enzyme Activation; Immunoblotting; Insulin; Mice; Mitogen-Activated Protein Kinase 1; Mitogens; Phosphorylcholine; Polyenes; Sirolimus; Thymidine; Wortmannin; Zinc | 1997 |
p70 S6 kinase-mediated protein synthesis is a critical step for vascular endothelial cell proliferation.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Chromones; DNA Replication; Endothelium, Vascular; Enzyme Inhibitors; Flavonoids; G1 Phase; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitosis; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Biosynthesis; Ribosomal Protein S6 Kinases; Sirolimus; Thymidine | 1999 |
Rapamycin inhibits human adipocyte differentiation in primary culture.
Topics: Adipocytes; Adipose Tissue; Azo Compounds; Cell Culture Techniques; Cell Differentiation; Cells, Cultured; Coloring Agents; Female; Glycerolphosphate Dehydrogenase; Humans; Immunosuppressive Agents; Male; Middle Aged; Scintillation Counting; Sirolimus; Thymidine | 2000 |
Regulation of the phosphatidylinositol 3-kinase, Akt/protein kinase B, FRAP/mammalian target of rapamycin, and ribosomal S6 kinase 1 signaling pathways by thyroid-stimulating hormone (TSH) and stimulating type TSH receptor antibodies in the thyroid gland.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Androstadienes; Animals; Blotting, Western; Cell Division; Cells, Cultured; Chromones; Dose-Response Relationship, Drug; Flow Cytometry; Gene Expression Regulation, Enzymologic; Humans; Immunoglobulin G; Immunohistochemistry; Microscopy, Confocal; Microscopy, Fluorescence; Models, Biological; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Isoforms; Protein Kinases; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; Sirolimus; Spectrometry, Fluorescence; Thymidine; Thyroid Gland; Thyrotropin; Time Factors; TOR Serine-Threonine Kinases; Transfection; Wortmannin | 2003 |
LY294002 and rapamycin co-operate to inhibit T-cell proliferation.
Topics: Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromones; Drug Interactions; Enzyme Inhibitors; Flow Cytometry; Humans; Interleukin-2; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Activation; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Sirolimus; T-Lymphocytes; Thymidine | 2005 |
Identification of WNK1 as a substrate of Akt/protein kinase B and a negative regulator of insulin-stimulated mitogenesis in 3T3-L1 cells.
Topics: 3T3-L1 Cells; Adipocytes; Androstadienes; Animals; Apoptosis; Binding Sites; Biological Transport; Cell Membrane; Cell Proliferation; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Glucose; Humans; Immunoblotting; Immunoprecipitation; Insulin; Intracellular Signaling Peptides and Proteins; Isoenzymes; Mass Spectrometry; Mice; Minor Histocompatibility Antigens; Peptides; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Ribosomal Protein S6 Kinases, 70-kDa; RNA Interference; RNA, Small Interfering; Signal Transduction; Sirolimus; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thymidine; Time Factors; Transfection; Trypsin; WNK Lysine-Deficient Protein Kinase 1; Wortmannin | 2005 |
Disruption of parallel and converging signaling pathways contributes to the synergistic antitumor effects of simultaneous mTOR and EGFR inhibition in GBM cells.
Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Apoptosis; Carrier Proteins; Cell Cycle Proteins; Cell Line, Tumor; Dose-Response Relationship, Drug; ErbB Receptors; Eukaryotic Initiation Factor-4E; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Immunoblotting; Immunoprecipitation; Models, Biological; Phosphoproteins; Phosphorylation; Protein Kinases; Quinazolines; Ribosomal Protein S6 Kinases; Signal Transduction; Sirolimus; Thymidine; TOR Serine-Threonine Kinases | 2005 |
Glucose-stimulated DNA synthesis through mammalian target of rapamycin (mTOR) is regulated by KATP channels: effects on cell cycle progression in rodent islets.
Topics: Animals; Blotting, Western; Calcium; Cell Cycle; Cell Division; Cell Proliferation; Cells, Cultured; Cytosol; Diazoxide; Dose-Response Relationship, Drug; Flow Cytometry; G2 Phase; Glucose; Glyburide; Islets of Langerhans; Male; Nifedipine; Potassium; Potassium Channels; Protein Kinases; Rats; Rats, Sprague-Dawley; S Phase; Sirolimus; Thymidine; TOR Serine-Threonine Kinases | 2006 |
Rapamycin at subimmunosuppressive levels inhibits mesangial cell proliferation and extracellular matrix production.
Topics: Animals; Apoptosis; Blotting, Western; Cell Count; Cell Proliferation; Cell Separation; Cell Survival; Collagen Type IV; Colorimetry; Dose-Response Relationship, Drug; Extracellular Matrix; Immunoprecipitation; Immunosuppressive Agents; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Mesangial Cells; Mice; Mice, Inbred C57BL; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinases, 70-kDa; Sirolimus; Thymidine | 2007 |
Rottlerin inhibits human T cell responses.
Topics: Acetophenones; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Benzopyrans; Blotting, Western; Calcium; CD28 Antigens; CD4-Positive T-Lymphocytes; CD8 Antigens; CD8-Positive T-Lymphocytes; Cell Proliferation; Cytokines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Humans; Interleukin-2; Interleukin-2 Receptor alpha Subunit; Intracellular Signaling Peptides and Proteins; Lectins, C-Type; Propidium; Protein Kinase C-delta; Protein Tyrosine Phosphatases; Protein Tyrosine Phosphatases, Non-Receptor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sirolimus; Th1 Cells; Th2 Cells; Thymidine | 2007 |
Effects of tacrolimus or sirolimus on proliferation of vascular smooth muscle and endothelial cells.
Topics: Blotting, Western; Cell Count; Cell Cycle; Cell Cycle Proteins; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Chemotaxis; DNA; Endothelial Cells; Humans; Immunosuppressive Agents; Inhibitory Concentration 50; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Platelet-Derived Growth Factor; Sirolimus; Tacrolimus; Thymidine; Tritium | 2006 |
Changes in tumor metabolism as readout for Mammalian target of rapamycin kinase inhibition by rapamycin in glioblastoma.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line, Tumor; Cell Proliferation; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Glioblastoma; Glucose; Humans; Mice; Positron-Emission Tomography; Protein Kinases; Sirolimus; Thymidine; Thymidine Kinase; TOR Serine-Threonine Kinases; Tyrosine | 2008 |