thymidine has been researched along with serine in 64 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (59.38) | 18.7374 |
| 1990's | 8 (12.50) | 18.2507 |
| 2000's | 14 (21.88) | 29.6817 |
| 2010's | 3 (4.69) | 24.3611 |
| 2020's | 1 (1.56) | 2.80 |
| Authors | Studies |
|---|---|
| Bradley, SG; Howe, DB | 1 |
| Arnold, HH; Kersten, H; Schmidt, W | 1 |
| Hofert, JF; Novak, RA | 1 |
| Karasek, M; Liu, SC | 1 |
| Chanarin, I; Taguchi, H | 1 |
| Dancer, BN; Mandelstam, J | 1 |
| Bolan, G; Lippman, M; Monaco, ME | 1 |
| Davis, RJ; Latour, DA; Raden, DL; Stanley, K; Theroux, SJ | 1 |
| Countaway, JL; Davis, RJ; Gironès, N; McQuilkin, P | 1 |
| Arakawa, T; Curless, C; Fox, GM; Hsu, YR; Schiffer, SG; Tsai, LB | 1 |
| Dziewiatkowski, DD; Lucas, PA | 1 |
| Brenner, L; Go, LT; Herbert, V; Tisman, G | 1 |
| Poirier, LA | 1 |
| Fuchs, P; Kohn, A; Neuhoff, V | 1 |
| Frank, W | 1 |
| Barbey, S; Despres, S; Nezelof, C; Rousseau, MF | 1 |
| Person, S; Sands, JA; Snipes, W | 1 |
| Guterman, SK | 1 |
| Kelln, RA; Warren, RA | 1 |
| Bell, RM | 1 |
| Miller, BA; Newman, EB | 1 |
| Angehrn, P; Then, R | 1 |
| Gallo, RC; Hecht, SM; O'Hopp, S; Whang-Peng, J | 1 |
| Brody, JI; Dubrow, R; Pizer, LI | 1 |
| Borun, TW; Marks, DB; Paik, WK | 1 |
| Leach, FR; Pierson, DL; Richardson, AG | 1 |
| Wolberg, WH | 2 |
| Faulcon, FM; Lee, WH; Regan, JD; Takeda, S; Vodopick, N | 1 |
| Bertino, JR; McCullough, JL; O'Brien, P | 1 |
| Greco, AE; Schneider, WC | 1 |
| Dvorkin, B; Makman, MH; White, A | 1 |
| Grippo, P; Iaccarino, M; Scarano, E; Winckelmans, D | 1 |
| Kemper, L; Vogel, FS | 1 |
| Baum, CL; Rosenberg, IH; Selhub, J | 1 |
| Adachi, K; Canalis, E; Hiraki, Y; Kato, Y; Nishikawa, K; Raisz, LG; Suzuki, F; Watanabe, R | 1 |
| Berwald-Netter, Y; Plet, A | 1 |
| Ishizuka, M; Kawatsu, M; Osono, M; Takeuchi, T; Yamashita, T | 1 |
| Hay, WW; Narkewicz, MR; Thureen, PJ; Townsend, SF | 1 |
| Gaulton, GN; Greene, WC; Kuziel, WA; Merida, I; Williamson, P | 1 |
| Chatterjee, S; Ghosh, N | 1 |
| Guyot, DJ; Lairmore, MD; Newbound, GC | 1 |
| Connolly, BA; Evans, SJ; Maughan, WN; Shipstone, EJ | 1 |
| Bebenek, A; Carver, GT; Drake, JW; Dressman, HK; Karam, JD; Konigsberg, WH; Ng , S; Petrov, V; Yang, G | 1 |
| Grosse-Wilde, H; Jacob, JR; Kreuzfelder, E; Maschke, J; Menne, S; Roggendorf, M; Tennant, BC | 1 |
| Fichera, A; Kumar, K; Xing, X | 1 |
| Clubb, RT; Daughdrill, GW; Ford, J; Iwahara, J; Iwahara, M | 1 |
| Akabani, G; Misra, UK; Pizzo, SV | 1 |
| Friesel, R; Harkins, LK; Kovalenko, D; Nadeau, RJ; Yang, X | 1 |
| MATSUYA, Y; YAMANE, I | 1 |
| MORSE, PA; POTTER, VR | 1 |
| AXELROD, AE; TRAKATELLIS, AC | 1 |
| Balbis, A; Baquiran, G; Dumas, V; Posner, BI | 1 |
| Chang, ZF; Ke, PY; Li, CL; Lu, CY | 1 |
| Chen, JM; Margot, NA; Miller, MD; Naeger, LK; Petropoulos, CJ; Swaminathan, S; White, KL; Wrin, T | 1 |
| Bianchi, V; Nordlund, P; Rinaldo-Matthis, A; Ruzzenente, B; Walldén, K | 1 |
| Misra, UK; Pizzo, SV | 1 |
| Brotherton, D; Molinari, A; Montagnoli, A; Rainoldi, S; Santocanale, C; Tenca, P; Troiani, S; Valsasina, B | 1 |
| Neary, JT; Washburn, KB | 1 |
| Baldwin, SA; Cass, CE; Karpinski, E; Loewen, SK; Ng, AM; Slugoski, MD; Smith, KM; Yao, SY; Young, JD | 1 |
| Brown, MC; Dobrikov, MI; Gromeier, M; Shveygert, M | 1 |
| Bhattacharya, A; Köhrer, C; Mandal, D; RajBhandary, UL | 1 |
| Abu-Remaileh, M; Birsoy, K; Boxer, MB; Brimacombe, KR; Chan, SH; Chen, WW; Cho, S; Chung, H; Davidson, SM; Fiske, BP; Freinkman, E; Gray, NS; Koh, MJ; Lewis, CA; Liu, CM; Liu, L; Luengo, A; Pacold, ME; Possemato, R; Rai, G; Rohde, JM; Sabatini, DM; Shaul, YD; Shen, M; Sullivan, LB; Swier, LJ; Vander Heiden, MG; Wang, AQ; Westover, KD; Xu, X; Yasgar, A; Zhou, M | 1 |
| Benjamin, SB; Drangowska-Way, A; Hilzendeger, MA; Joshi, C; Ke, W; Lewis, N; Locasale, J; Mony, VK; O'Rourke, EJ; Patti, GJ; Saba, JA; Yao, CH; Zhang, S | 1 |
64 other study(ies) available for thymidine and serine
| Article | Year |
|---|---|
Perturbation by bacterial lipopolysaccharide of the metabolic processes of human cells in continuous culture.
Topics: Adenine; Amino Acids; Cell Line; Cells, Cultured; Cycloheximide; Dactinomycin; Endotoxins; Leucine; Lipopolysaccharides; Plicamycin; Polysaccharides, Bacterial; Pyrimidine Nucleosides; Serine; Thymidine; Uridine; Vincristine | 1976 |
Occurrence and biosynthesis of ribothymidine in tRNAs of B. subtilis.
Topics: Bacillus subtilis; Chromatography, Thin Layer; Formates; Methionine; Phosphoric Diester Hydrolases; Ribonucleosides; Ribonucleotides; RNA, Bacterial; RNA, Transfer; Serine; Snake Venoms; Thymidine; Uridine | 1975 |
A differential effect of L-serine on the incorporation of 3H-deoxycytidine and 3H-thymidine into DNA of rat thymocytes.
Topics: Animals; Cells, Cultured; Deoxycytidine; DNA; Male; Rats; Serine; T-Lymphocytes; Thymidine | 1978 |
Isolation and serial cultivation of rabbit skin epithelial cells.
Topics: Animals; Cell Division; Cells, Cultured; Collagen; Culture Media; Cytological Techniques; Edetic Acid; Egtazic Acid; Epithelial Cells; Epithelium; Female; Male; Methotrexate; Phosphates; Rabbits; Serine; Skin; Thymidine; Trypsin | 1978 |
The effect of homocysteine, methionine, serine and glycine on DNA synthesis by human normoblastic and megaloblastic bone marrow cells.
Topics: Bone Marrow Cells; Cell Survival; Deoxyuridine; DNA; Erythrocytes, Abnormal; Glycine; Homocysteine; Humans; Megaloblasts; Methionine; Serine; Thymidine | 1978 |
Criteria for categorizing early biochemical events occurring during sporulation of Bacillus subtilis.
Topics: Alkaline Phosphatase; Amylases; Bacillus subtilis; Cell-Free System; Endopeptidases; Fluorides; Mutation; Pronase; Ribonucleases; Serine; Spores, Bacterial; Sulfonic Acids; Thymidine | 1975 |
Effects of estrone, estradiol, and estriol on hormone-responsive human breast cancer in long-term tissue culture.
Topics: Binding, Competitive; Breast Neoplasms; Cell Nucleus; Culture Techniques; Cytoplasm; Drug Interactions; Estradiol; Estriol; Estrone; Humans; Receptors, Estrogen; Serine; Tamoxifen; Thymidine | 1977 |
Signal transduction by the epidermal growth factor receptor is attenuated by a COOH-terminal domain serine phosphorylation site.
Topics: Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; CHO Cells; Cricetinae; DNA Replication; Epidermal Growth Factor; ErbB Receptors; Humans; Kinetics; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Peptides; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Serine; Signal Transduction; Substrate Specificity; Thymidine; Transfection; Tyrosine | 1992 |
Multisite phosphorylation of the epidermal growth factor receptor. Use of site-directed mutagenesis to examine the role of serine/threonine phosphorylation.
Topics: Amino Acid Sequence; Amino Acids; Animals; Cell Line; DNA Replication; Epidermal Growth Factor; ErbB Receptors; Humans; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Peptide Fragments; Phosphopeptides; Phosphorylation; Plasmids; Platelet-Derived Growth Factor; Serine; Threonine; Thymidine | 1990 |
Characterization of a cysteine-free analog of recombinant human basic fibroblast growth factor.
Topics: Amino Acid Sequence; Animals; Cell Line; Circular Dichroism; Cysteine; Escherichia coli; Fibroblast Growth Factors; Genetic Vectors; Hydrogen-Ion Concentration; Mice; Oligonucleotide Probes; Recombinant Proteins; Serine; Spectrometry, Fluorescence; Thymidine | 1989 |
Feedback control of selected biosynthetic activities of chondrocytes in culture.
Topics: Animals; Cartilage; Cell Count; Chickens; Chondrosarcoma; Collagen; Comb and Wattles; Feedback; Humans; Hyaluronic Acid; Proline; Protein Biosynthesis; Proteoglycans; Rats; Serine; Sulfates; Thymidine; Tumor Cells, Cultured; Umbilical Cord | 1987 |
Inhibition by penicillamine of DNA and protein synthesis by human bone marrow.
Topics: Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Copper; Deoxyuridine; Depression, Chemical; DNA; Formates; Humans; Ilium; In Vitro Techniques; Iron; Neoplasms; Penicillamine; Perchlorates; Protein Biosynthesis; RNA; Serine; Stereoisomerism; Thymidine; Tritium; Uridine; Zinc | 1972 |
Folate deficiency in rats bearing the Walker tumor 256 and the Novikoff hepatoma.
Topics: Adenine; Animals; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Choline; Diet; FIGLU Test; Folic Acid; Folic Acid Deficiency; Formates; Glycine; Guanine; Liver Neoplasms; Male; Methionine; Neoplasms, Experimental; Rats; Serine; Thymidine; Vitamin B 12 | 1973 |
Inhibition of the tetrahydrofolic acid cycle in HeLa and LDR cells by parainfluenza virus 1 (Sendai).
Topics: Adenine; Adsorption; Animals; Carbon Radioisotopes; Cells, Cultured; Chromatography, Thin Layer; Culture Media; Dansyl Compounds; DNA; Fibroblasts; Formates; Guanine; HeLa Cells; Humans; Mice; Nucleotides; Parainfluenza Virus 1, Human; RNA; Serine; Spectrophotometry, Ultraviolet; Tetrahydrofolates; Thymidine; Tritium | 1974 |
[Deficiency of C2-fragments in the metabolism of embryonic rat cells in culture].
Topics: Animals; Carbon Isotopes; Cattle; Culture Techniques; Embryo, Mammalian; Glyoxylates; Immune Sera; Rats; Serine; Thymidine; Tritium | 1971 |
[Histocytosis-X. Histochemical and autoradiographic elements proving lipid synthesis in in vitro culture].
Topics: Acetates; Autoradiography; Carbon Radioisotopes; Cell Membrane; Choline; Culture Techniques; Eosinophilic Granuloma; Esterases; Fibroblasts; Glycerol; Glycine; Histiocytes; Histocytochemistry; Humans; Leucyl Aminopeptidase; Lipids; Lymphatic Diseases; Mevalonic Acid; Palmitates; Serine; Thymidine; Tritium; Uridine | 1974 |
Mutagenesis by tritium: decays originating from growth and storage in tritiated water and from chemostatic growth in the presence of tritiated nucleic acid precursors.
Topics: Arginine; Bacteriological Techniques; Cell Survival; Computers; DNA Repair; Escherichia coli; Genetics, Microbial; Half-Life; Mutation; Radiation Effects; Radiation Genetics; Serine; Thymidine; Time Factors; Tritium; Uracil; Water | 1972 |
Colicin B: mode of action and inhibition by enterochelin.
Topics: Adsorption; Benzoates; Carbon Isotopes; Catechols; Colicins; Culture Media; Genetics, Microbial; Iron Chelating Agents; Leucine; Lipopolysaccharides; Microbial Sensitivity Tests; Salmonella; Salmonella typhimurium; Serine; Thymidine; Time Factors; Uracil | 1973 |
Studies on the biosynthesis of alpha-putrescinylthymine in bacteriophage phi W-14-infected Pseudomonas acidovorans.
Topics: Bacteriophages; Carbon Radioisotopes; Cell-Free System; Chromatography, Paper; DNA Replication; DNA, Viral; Escherichia coli; Formaldehyde; Pseudomonas; Putrescine; Pyrimidines; Serine; Spectrophotometry; Tetrahydrofolates; Thymidine; Thymidylate Synthase; Thymine; Transferases; Tritium; Uracil | 1973 |
Mutants of Escherichia coli defective in membrane phospholipid synthesis: macromolecular synthesis in an sn-glycerol 3-phosphate acyltransferase Km mutant.
Topics: Acetates; Acyltransferases; Bacterial Proteins; Carbon Radioisotopes; Cell Membrane; Cell-Free System; DNA, Bacterial; Escherichia coli; Glucose; Glycerol; Glycerolphosphate Dehydrogenase; Glycerophosphates; Leucine; Mutation; Phosphates; Phospholipids; RNA, Bacterial; Serine; Thymidine; Tritium; Uracil | 1974 |
Control of serine transhydroxymethylase synthesis in Escherichia coli K12.
Topics: Adenine; Culture Media; Escherichia coli; Formates; Glycine; Guanine; Histidine; Isoleucine; Methionine; Mutation; Serine; Thymidine; Transferases; Tritium; Valine | 1974 |
The biochemical basis of the antimicrobial action of sulfonamides and trimethoprim in vivo--I. Action of sulfonamides and trimethoprim in blood and urine.
Topics: Amino Acids; Blood Bactericidal Activity; Culture Media; Drug Interactions; Escherichia coli; Folic Acid Antagonists; Glycine; Humans; Kinetics; Methionine; Purines; Serine; Sulfamethoxazole; Sulfonamides; Thymidine; Thymine; Time Factors; Trimethoprim | 1974 |
N 6 -( 2 -Isopentenyl)adenosine: the regulatory effects of a cytokinin and modified nucleoside from tRNA on human lymphocytes.
Topics: Adenosine; Binding Sites; Carbon Isotopes; DNA; Genetic Code; Humans; Lectins; Lymphocyte Activation; Lymphocytes; Mitosis; Phosphotransferases; Plant Growth Regulators; Protein Binding; RNA; RNA, Messenger; RNA, Transfer; Serine; Structure-Activity Relationship; Thymidine; Uridine | 1972 |
Serine-glycine requirement of phytohemagglutinin-stimulated lymphocytes.
Topics: Carbon Isotopes; Cell Division; DNA; Glycine; Humans; Lectins; Leucine; Lymphocytes; Serine; Thymidine | 1973 |
The relationship of histone phosphorylation to deoxyribonucleci acid replication and mitosis during the HeLa S-3 cell cycle.
Topics: Cell Nucleus; Chromatids; Cytarabine; Cytoplasm; DNA Replication; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Genes; HeLa Cells; Histones; Mitosis; Phosphates; Phospholipids; Phosphoproteins; Phosphorus Isotopes; RNA, Neoplasm; Serine; Thymidine | 1973 |
The effect of phenethyl alcohol on Bacillus subtilis transformation. II. Transport of DNA and precursors.
Topics: Bacillus subtilis; Bacterial Proteins; Carbon Isotopes; Cell Membrane Permeability; Deoxyribonucleases; Depression, Chemical; DNA, Bacterial; Ethanol; Kinetics; RNA, Bacterial; Serine; Thymidine; Toluene; Transformation, Genetic; Tritium; Uracil | 1969 |
Response of DNA thymine synthesis in human tumor and normal tissue to 5-fluorouracil.
Topics: Breast Neoplasms; Carbon Isotopes; Chromatography, Paper; Colon; Colonic Neoplasms; Depression, Chemical; DNA; DNA, Neoplasm; Female; Fluorouracil; Formates; Humans; In Vitro Techniques; Lung Neoplasms; Methyltransferases; Ovarian Neoplasms; Serine; Thymidine; Thymine; Thymine Nucleotides; Tritium; Uracil Nucleotides | 1972 |
Serine requirement in leukemic and normal blood cells.
Topics: Alanine; Asparagine; Aspartic Acid; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Culture Media; DNA, Neoplasm; Fibroblasts; Glucose; Glutamates; Glycine; Humans; In Vitro Techniques; Leukemia, Myeloid; Neoplasm Proteins; Proline; RNA, Neoplasm; Serine; Thymidine; Tritium; Uridine | 1969 |
Inhibition of growth of leukemia cells by enzymic folate depletion.
Topics: Animals; Carboxypeptidases; Carcinoma 256, Walker; Cell Line; Culture Media; Depression, Chemical; Folic Acid; Humans; Hypoxanthines; In Vitro Techniques; Leucovorin; Leukemia L1210; Leukemia, Experimental; Methotrexate; Pseudomonas; Serine; Thymidine | 1971 |
Incorporation of pyrimidine deoxyribonucleosides into liver lipids and other components.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Aspartic Acid; Cell Nucleus; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Deoxyribonucleosides; Deoxyuridine; DNA; Fatty Acids; Glutamates; Glycerides; Glycerol; Glycerylphosphorylcholine; Hydrolysis; Lipids; Liver; Male; Methionine; Mice; Microsomes, Liver; Mitochondria, Liver; Nucleosides; Phosphatidylcholines; Phosphatidylethanolamines; Protein Biosynthesis; Rats; Serine; Thymidine; Thymine; Tritium | 1971 |
Alternative pathways for DNA-thymine synthesis in stimulated leucocytes.
Topics: Carbon Isotopes; DNA; Formates; Humans; In Vitro Techniques; Lectins; Leukocytes; Lymphocyte Activation; Serine; Thymidine; Thymine; Tritium | 1971 |
Influence of cortisol on the utilization of precursors of nucleic acids and protein by lymphoid cells in vitro.
Topics: Adrenal Glands; Adrenalectomy; Aminoisobutyric Acids; Animals; Carbon Isotopes; Cold Temperature; Cycloparaffins; DNA; Glucose; Glycine; Hydrocortisone; In Vitro Techniques; Leucine; Lymph Nodes; Lymphoid Tissue; Male; Mesentery; Nucleic Acids; Phenylalanine; Protein Biosynthesis; Rabbits; Rats; RNA; Serine; Thymidine; Thymus Gland; Tissue Extracts; Tritium; Uridine | 1968 |
On methylation of DNA during development of the sea urchin embryo.
Topics: Alkylation; Animals; DNA; Echinodermata; Embryo, Nonmammalian; In Vitro Techniques; Methionine; Serine; Thymidine | 1965 |
Intrinsic ribonucleic acid synthesis in mitochondria of Agaricus campestris underscoring the probability of an extra-nuclear genetic system.
Topics: Amines; Bacteria; Basidiomycota; Carbon Isotopes; Choline; DNA; Genetics; Microscopy, Electron; Mitochondria; Nitrogen; RNA; Serine; Thymidine; Tritium; Uracil | 1967 |
Antifolate actions of sulfasalazine on intact lymphocytes.
Topics: Animals; Burkitt Lymphoma; Cell Line; Deoxyuridine; DNA; Folic Acid Antagonists; Formates; Lymphocytes; Rats; Serine; Sulfasalazine; Thymidine | 1981 |
Selective stimulation of sulfated glycosaminoglycan synthesis by multiplication-stimulating activity, cartilage-derived factor and bone-derived growth factor. Comparison of their actions on cultured chondrocytes with those of fibroblast growth factor and
Topics: Animals; Cartilage; DNA Replication; Fibroblast Growth Factors; Glucosamine; Glycosaminoglycans; Growth Substances; Insulin-Like Growth Factor II; Peptides; Proteins; Rabbits; Serine; Sulfates; Thymidine | 1982 |
The relative contribution of somatomedin to the serum-stimulated growth of human fibroblasts.
Topics: Cell Division; Cells, Cultured; Culture Media; DNA; Fibroblasts; Humans; Infant, Newborn; Kinetics; Male; Serine; Skin; Skin Physiological Phenomena; Somatomedins; Thymidine | 1980 |
T cell activation by conagenin in mice.
Topics: Adjuvants, Immunologic; Animals; Cells, Cultured; Female; Lymphocyte Activation; Lymphokines; Mice; Serine; Spleen; T-Lymphocytes; Thymidine | 1993 |
Development of primary culture of ovine fetal hepatocytes for studies of amino acid metabolism and insulinlike growth factors.
Topics: Amino Acids; Animals; Cell Division; Cell Separation; Cells, Cultured; DNA; Female; Fetus; Gene Expression; Glucose; Glycine; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Lactates; Liver; Pregnancy; RNA, Messenger; Serine; Sheep; Thymidine | 1993 |
The serine-rich cytoplasmic domain of the interleukin-2 receptor beta chain is essential for interleukin-2-dependent tyrosine protein kinase and phosphatidylinositol-3-kinase activation.
Topics: 1-Phosphatidylinositol 4-Kinase; Animals; Base Sequence; Cell Line; Cytoplasm; DNA, Single-Stranded; Enzyme Activation; Humans; Interleukin-2; Mice; Molecular Sequence Data; Phosphorylation; Phosphotransferases; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Receptors, Interleukin-2; RNA, Messenger; Serine; Thymidine | 1993 |
Oxidized low density lipoprotein stimulates aortic smooth muscle cell proliferation.
Topics: Animals; Antibodies; Antigens, CD; Aorta; Cell Division; Enzyme Activation; Enzyme Inhibitors; Galactose; Galactosyltransferases; Glycoside Hydrolases; Glycosyltransferases; Kinetics; Lactosylceramides; Lipoproteins, LDL; Models, Biological; Morpholines; Muscle, Smooth, Vascular; Rabbits; Serine; Signal Transduction; Temperature; Thymidine | 1996 |
Co-stimulation of human peripheral blood mononuclear cells with IL-2 and anti-CD3 monoclonal antibodies induces phosphorylation of CREB.
Topics: Antibodies, Monoclonal; CD2 Antigens; CD3 Complex; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; DNA; Humans; Interleukin-2; Leukocytes, Mononuclear; Lymphocyte Activation; Oligonucleotide Probes; Phosphorylation; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Receptor-CD3 Complex, Antigen, T-Cell; Receptors, Interleukin-2; Serine; Signal Transduction; Thymidine | 1998 |
Site-directed mutagenesis of phosphate-contacting amino acids of bovine pancreatic deoxyribonuclease I.
Topics: Amino Acids; Animals; Arginine; Asparagine; Cattle; Deoxyribonuclease I; DNA; Hydrolysis; Mutagenesis, Site-Directed; RNA, Transfer, Tyr; Serine; Substrate Specificity; Sugar Phosphates; Threonine; Thymidine; Tyrosine | 1999 |
Interacting fidelity defects in the replicative DNA polymerase of bacteriophage RB69.
Topics: Alanine; Alleles; Bacteriophages; Base Sequence; Cell Division; Chromatography, Gel; Cloning, Molecular; DNA Replication; DNA-Directed DNA Polymerase; Escherichia coli; Genetic Complementation Test; Kinetics; Molecular Sequence Data; Mutagenesis; Mutation; Plasmids; Sequence Homology, Nucleic Acid; Serine; Threonine; Thymidine; Time Factors; Viral Proteins | 2001 |
Thymidine utilization abnormality in proliferating lymphocytes and hepatocytes of the woodchuck.
Topics: 3T3 Cells; Adenine; Animals; Blotting, Northern; Blotting, Southern; Cell Division; Humans; Liver; Lymphocytes; Marmota; Methotrexate; Mice; Models, Biological; Serine; Thymidine; Thymidine Kinase; Thymidine Monophosphate | 2001 |
A novel synthesis of enantiomerically pure 5,5,5,5',5',5'-hexafluoroleucine.
Topics: Amidohydrolases; Dipeptides; Leucine; Magnetic Resonance Spectroscopy; Molecular Structure; Serine; Stereoisomerism; Thymidine | 2001 |
The structure of the Dead ringer-DNA complex reveals how AT-rich interaction domains (ARIDs) recognize DNA.
Topics: Adenine; Amino Acid Sequence; Animals; Base Pairing; Binding Sites; Consensus Sequence; DNA; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; Helix-Turn-Helix Motifs; Homeodomain Proteins; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Conformation; Protein Binding; Protein Conformation; Protein Interaction Mapping; Protein Structure, Tertiary; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Structure-Activity Relationship; Substrate Specificity; Thymidine | 2002 |
The role of cAMP-dependent signaling in receptor-recognized forms of alpha 2-macroglobulin-induced cellular proliferation.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; alpha-Macroglobulins; Animals; Blotting, Western; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Enzyme Inhibitors; GRB2 Adaptor Protein; Macrophages; Mice; Models, Biological; Phosphatidylinositol 3-Kinases; Phosphorylation; Proteins; Proto-Oncogene Proteins c-fos; ras Proteins; RNA; RNA, Double-Stranded; Serine; Shc Signaling Adaptor Proteins; Signal Transduction; SOS1 Protein; Src Homology 2 Domain-Containing, Transforming Protein 1; Thymidine; Time Factors; Transfection | 2002 |
Sef inhibits fibroblast growth factor signaling by inhibiting FGFR1 tyrosine phosphorylation and subsequent ERK activation.
Topics: 3T3 Cells; Adenoviridae; Animals; Cell Division; Cell Line; Cloning, Molecular; COS Cells; Enzyme Activation; Fibroblast Growth Factors; Gene Expression Regulation, Enzymologic; Genetic Vectors; Humans; Immunoblotting; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Membrane Proteins; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Platelet-Derived Growth Factor; Precipitin Tests; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Serine; Signal Transduction; Threonine; Thymidine; Tyrosine | 2003 |
CULTURE OF SINGLE MAMMALIAN CELLS.
Topics: Animals; Cattle; Cholesterol; Corrinoids; Culture Media; Insulin; Leucovorin; Research; Research Design; Serine; Thymidine; Tissue Culture Techniques; Vitamin B 12 | 1963 |
PYRIMIDINE METABOLISM IN TISSUE CULTURE CELLS DERIVED FROM RAT HEPATOMAS. I. SUSPENSION CELL CULTURES DERIVED FROM THE NOVIKOFF HEPATOMA.
Topics: Animals; Carcinoma, Hepatocellular; Cell Culture Techniques; Floxuridine; Fluorouracil; Glycine; Liver Neoplasms; Liver Neoplasms, Experimental; Metabolism; Methotrexate; Mutation; Neoplasms; Neoplasms, Experimental; Nucleosides; Pharmacology; Pyrimidines; Rats; Research; Serine; Thymidine; Thymidine Kinase; Thymine; Tissue Culture Techniques; Toxicology; Uracil | 1965 |
EFFECT OF PYRIDOXINE DEFICIENCY ON NUCLEIC ACID METABOLISM IN THE RAT.
Topics: Adenine; DNA; Formates; Liver; Metabolism; Methionine; Nucleic Acids; Nucleosides; Pyridoxal Phosphate; Rats; Research; RNA; Serine; Spleen; Thymidine; Transferases; Vitamin B 6 Deficiency | 1965 |
Effect of inhibiting vacuolar acidification on insulin signaling in hepatocytes.
Topics: Animals; Antioxidants; Binding Sites; Cell Division; Cell Membrane; Cells, Cultured; Chloroquine; Endosomes; Enzyme Inhibitors; Evolution, Molecular; Glycogen; Hepatocytes; Histidine; Insulin; Macrolides; Male; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Mutation; Phosphatidylinositol 3-Kinases; Phosphorylation; Phylogeny; Rats; Rats, Sprague-Dawley; Serine; Signal Transduction; Superoxides; Swine; Thymidine; Time Factors; Tyrosine | 2004 |
Perturbation of ATP-induced tetramerization of human cytosolic thymidine kinase by substitution of serine-13 with aspartic acid at the mitotic phosphorylation site.
Topics: Adenosine Triphosphate; Aspartic Acid; Catalysis; Cell Cycle; Cell Line; Chromatography; Chromatography, Gel; Cytosol; Dimerization; Dose-Response Relationship, Drug; G2 Phase; Humans; Kinetics; Mitosis; Models, Biological; Mutation; Phosphorylation; Plasmids; Protein Structure, Quaternary; Serine; Thymidine; Thymidine Kinase | 2004 |
Molecular mechanisms of tenofovir resistance conferred by human immunodeficiency virus type 1 reverse transcriptase containing a diserine insertion after residue 69 and multiple thymidine analog-associated mutations.
Topics: Adenine; Adenosine Triphosphate; Cells, Cultured; DNA Primers; DNA Transposable Elements; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Models, Molecular; Mutation; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Serine; Tenofovir; Thymidine | 2004 |
Structural basis for substrate specificity of the human mitochondrial deoxyribonucleotidase.
Topics: 5'-Nucleotidase; Binding Sites; Crystallography, X-Ray; Dinucleoside Phosphates; Electrons; Humans; Isoleucine; Kinetics; Mitochondria; Models, Molecular; Mutagenesis, Site-Directed; Nucleosides; Protein Binding; Serine; Substrate Specificity; Thymidine; Thymidine Monophosphate | 2005 |
Coordinate regulation of forskolin-induced cellular proliferation in macrophages by protein kinase A/cAMP-response element-binding protein (CREB) and Epac1-Rap1 signaling: effects of silencing CREB gene expression on Akt activation.
Topics: Androstadienes; Animals; bcl-Associated Death Protein; Blotting, Western; Cell Count; Cell Proliferation; Chromones; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cyclin D1; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation; Gene Silencing; Guanine Nucleotide Exchange Factors; Guanosine Triphosphate; Immunoprecipitation; Isoquinolines; Macrophages; Mice; Mice, Inbred C57BL; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; rap1 GTP-Binding Proteins; RNA Interference; RNA, Double-Stranded; Serine; Signal Transduction; Sulfonamides; Threonine; Thymidine; Time Factors; Up-Regulation; Wortmannin; X-Linked Inhibitor of Apoptosis Protein | 2005 |
Identification of Mcm2 phosphorylation sites by S-phase-regulating kinases.
Topics: Amino Acid Sequence; Binding Sites; Blotting, Western; Casein Kinase II; CDC2 Protein Kinase; Cell Cycle; Cell Cycle Proteins; Chromatin; Chromatography, Liquid; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase-Activating Kinase; Cyclin-Dependent Kinases; DNA Helicases; Electrophoresis, Polyacrylamide Gel; Fibroblasts; HeLa Cells; Humans; Ions; Luciferases; Mass Spectrometry; Microscopy, Fluorescence; Minichromosome Maintenance Complex Component 2; Molecular Sequence Data; Nuclear Proteins; Peptides; Phosphorylation; Proline; Protein Isoforms; Protein Structure, Tertiary; Recombinant Fusion Proteins; S-Phase Kinase-Associated Proteins; Serine; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thymidine; Transfection; Trypsin | 2006 |
P2 purinergic receptors signal to STAT3 in astrocytes: Difference in STAT3 responses to P2Y and P2X receptor activation.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Astrocytes; Blotting, Western; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X; Receptors, Purinergic P2Y1; Serine; Signal Transduction; STAT3 Transcription Factor; Suramin; Theophylline; Thymidine; Time Factors; Tritium; Uridine Triphosphate | 2006 |
Specific mutations in transmembrane helix 8 of human concentrative Na+/nucleoside cotransporter hCNT1 affect permeant selectivity and cation coupling.
Topics: 4-Chloromercuribenzenesulfonate; Amino Acid Sequence; Animals; Cations, Monovalent; Cytidine; Humans; Kinetics; Leucine; Lithium; Membrane Transport Proteins; Protein Structure, Secondary; Serine; Sodium; Substrate Specificity; Thymidine; Uridine; Xenopus laevis | 2007 |
Mitotic phosphorylation of eukaryotic initiation factor 4G1 (eIF4G1) at Ser1232 by Cdk1:cyclin B inhibits eIF4A helicase complex binding with RNA.
Topics: Adenine; CDC2 Protein Kinase; Cell Cycle; Cyclin B1; Eukaryotic Initiation Factor-4A; Eukaryotic Initiation Factor-4G; Flow Cytometry; HEK293 Cells; HeLa Cells; Humans; Immunoblotting; Interphase; Intracellular Signaling Peptides and Proteins; Mitosis; Mutation; Nocodazole; Phosphorylation; Protein Binding; Protein Biosynthesis; Protein Serine-Threonine Kinases; Proteomics; RNA; Serine; Thymidine; Tubulin Modulators | 2014 |
Nonsense suppression in archaea.
Topics: Archaea; Base Sequence; beta-Galactosidase; Codon, Nonsense; Codon, Terminator; Escherichia coli; Genes, Suppressor; Haloferax volcanii; Molecular Sequence Data; Novobiocin; Plasmids; Promoter Regions, Genetic; RNA, Transfer; Serine; Suppression, Genetic; Thymidine; Tryptophan; Uracil | 2015 |
A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate.
Topics: Animals; Carbon; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Glycolysis; Humans; Mammary Neoplasms, Experimental; Mice; Molecular Structure; Phosphoglycerate Dehydrogenase; Purines; Serine; Small Molecule Libraries; Structure-Activity Relationship; Thymidine; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2016 |
Dietary serine-microbiota interaction enhances chemotherapeutic toxicity without altering drug conversion.
Topics: Animals; Caenorhabditis elegans; Dietary Supplements; Escherichia coli; Floxuridine; Folic Acid; Food-Drug Interactions; Gastrointestinal Microbiome; Serine; Thymidine; Uracil Nucleotides | 2020 |