thymidine has been researched along with pemetrexed in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 7 (63.64) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gangjee, A; Jain, HD; Kisliuk, RL; McGuire, JJ | 1 |
| Gangjee, A; Kisliuk, RL; Lin, X; McGuire, JJ | 1 |
| Barnett, CJ; Grindey, GB; Wilson, TM | 1 |
| Calvert, AH; Curtin, NJ; Marshman, E; Newell, DR; Smith, PG | 1 |
| Curtin, NJ; Marshman, E; Newell, DR; Smith, PG | 1 |
| Backus, HH; Bunni, MA; Comijn, L; Jackman, AL; Jansen, G; Mitchell, F; Peters, GJ; Priest, DG; Smid, K; van der Wilt, CL; Veerman, G; Voorn, DA; Wouters, D | 1 |
| Barlow, HC; Calvert, AH; Curtin, NJ; Golding, BT; Griffin, RJ; Newell, DR; Smith, PG; Thomas, HD | 1 |
| Clarke, SJ; Li, KM; Rivory, LP | 1 |
| Barlow, H; Barton, M; Curtin, NJ; Golding, BT; Griffin, RJ; Lin, MJ; Newell, DR; Northen, JS; Saravanan, K; Thomas, HD; Wang, LZ | 1 |
| Leamon, CP; Müller, C; Reber, J; Schibli, R; Schlup, C | 1 |
| Aggarwal, C; Albelda, SM; Berger, I; Cai, J; Chen, X; Farwell, MD; Katz, SI; Khalid, U; Langer, C; Patel, A; Yang, Y | 1 |
1 trial(s) available for thymidine and pemetrexed
| Article | Year |
|---|---|
Pemetrexed pharmacokinetics and pharmacodynamics in a phase I/II study of doublet chemotherapy with vinorelbine: implications for further optimisation of pemetrexed schedules.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carcinoma, Non-Small-Cell Lung; Deoxyuridine; Dietary Supplements; Dose-Response Relationship, Drug; Female; Folic Acid; Glutamates; Guanine; Homocysteine; Humans; Lung Neoplasms; Male; Methylmalonic Acid; Middle Aged; Pemetrexed; Thymidine; Thymidylate Synthase; Vinblastine; Vinorelbine; Vitamin B 12 | 2007 |
10 other study(ies) available for thymidine and pemetrexed
| Article | Year |
|---|---|
Benzoyl ring halogenated classical 2-amino-6-methyl-3,4-dihydro-4-oxo-5-substituted thiobenzoyl-7H-pyrrolo[2,3-d]pyrimidine antifolates as inhibitors of thymidylate synthase and as antitumor agents.
Topics: Antineoplastic Agents; Cell Line, Tumor; Enzyme Inhibitors; Folic Acid Antagonists; Humans; Pyrimidines; Structure-Activity Relationship; Thymidylate Synthase | 2004 |
Synthesis of N-{4-[(2,4-diamino-5-methyl-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)thio]benzoyl}-L-glutamic acid and N-{4-[(2-amino-4-oxo-5-methyl-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)thio]benzoyl}-L-glutamic acid as dual inhibitors of dihydrofol
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Escherichia coli; Folic Acid Antagonists; Glutamates; Humans; Models, Molecular; Pyrimidines; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Toxoplasma | 2005 |
Synthesis and antitumor activity of LY288601, the 5,6-dihydro analog of LY231514.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Folic Acid Antagonists; Glutamates; Guanine; Humans; Hypoxanthine; Hypoxanthines; Lymphoma; Mice; Molecular Structure; Pemetrexed; Structure-Activity Relationship; Thymidine; Tumor Cells, Cultured | 1993 |
Prevention of thymidine and hypoxanthine rescue from MTA (LY231514) growth inhibition by dipyridamole in human lung cancer cell lines.
Topics: Antimetabolites, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Cell Division; Dipyridamole; Enzyme Inhibitors; Folic Acid Antagonists; Glutamates; Guanine; Humans; Hypoxanthine; Lung Neoplasms; Pemetrexed; Phosphodiesterase Inhibitors; Thymidine; Thymidylate Synthase; Tumor Cells, Cultured | 1999 |
Dipyridamole potentiates the in vitro activity of MTA (LY231514) by inhibition of thymidine transport.
Topics: Biological Transport; Dipyridamole; Drug Synergism; Enzyme Inhibitors; Glutamates; Guanine; Humans; Pemetrexed; Thymidine; Thymidylate Synthase; Tumor Cells, Cultured | 2000 |
Modulation of both endogenous folates and thymidine enhance the therapeutic efficacy of thymidylate synthase inhibitors.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Division; Colonic Neoplasms; Diet; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Female; Fluorouracil; Folic Acid; Folic Acid Antagonists; Glutamates; Guanine; Leucovorin; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Pemetrexed; Quinazolines; Thiophenes; Thymidine; Thymidine Kinase; Thymidylate Synthase | 2001 |
In vitro and in vivo properties of novel nucleoside transport inhibitors with improved pharmacological properties that potentiate antifolate activity.
Topics: Animals; Carrier Proteins; Cell Division; Dipyridamole; Dose-Response Relationship, Drug; Drug Synergism; Female; Folic Acid Antagonists; Glutamates; Guanine; Humans; Hypoxanthine; Liver; Membrane Proteins; Mice; Mice, Inbred BALB C; Nucleoside Transport Proteins; Orosomucoid; Pemetrexed; Tetrahydrofolates; Thymidine; Time Factors; Tritium; Tumor Cells, Cultured | 2001 |
Preclinical evaluation of a novel pyrimidopyrimidine for the prevention of nucleoside and nucleobase reversal of antifolate cytotoxicity.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Proliferation; Dipyridamole; Drug Synergism; Female; Folic Acid Antagonists; Glutamates; Guanine; Humans; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Nucleosides; Orosomucoid; Pemetrexed; Phosphorylation; Prodrugs; Thymidine; Thymidylate Synthase; Tissue Distribution; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2009 |
In vitro and in vivo evaluation of an innocuous drug cocktail to improve the quality of folic acid targeted nuclear imaging in preclinical research.
Topics: Animals; Diagnostic Imaging; Female; Folic Acid Antagonists; Glutamates; Guanine; Humans; Hypoxanthine; KB Cells; Mice; Pemetrexed; Radiopharmaceuticals; Thymidine; Tomography, Emission-Computed, Single-Photon | 2013 |
Early detection of pemetrexed-induced inhibition of thymidylate synthase in non-small cell lung cancer with FLT-PET imaging.
Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Disease Models, Animal; Equilibrative Nucleoside Transporter 1; Female; Humans; Image Processing, Computer-Assisted; Lung Neoplasms; Mice; Pemetrexed; Positron-Emission Tomography; Radiopharmaceuticals; Thymidine; Thymidine Kinase; Thymidylate Synthase; Time Factors; Xenograft Model Antitumor Assays | 2017 |