thymidine has been researched along with oligonucleotides in 208 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 52 (25.00) | 18.7374 |
| 1990's | 28 (13.46) | 18.2507 |
| 2000's | 84 (40.38) | 29.6817 |
| 2010's | 36 (17.31) | 24.3611 |
| 2020's | 8 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Brady, JT; Odom, DG; Oro, J | 1 |
| Singer, B | 1 |
| Kalisch, BW; van de Sande, JH | 1 |
| Usher, DA; Yee, D | 1 |
| Birch-Hirschfeld, E; Lang, H; Zimmer, C | 1 |
| LéJohn, HB; Lewis, WH; McNaughton, DR; Wright, JA | 1 |
| Joenje, H; Venema, G | 1 |
| Al-Mukhtar, J; Wilson, HR | 1 |
| Bayer, E; Eckstein, H; Gatfield, I; Schott, H | 1 |
| Barascut, JL; Bellon, L; Imbach, JL; Morvan, F | 1 |
| Crooke, RM; Hoke, GD; Shoemaker, JE | 1 |
| Asseline, U; Czernecki, S; Hau, JF; Le Diguarher, T; Perlat, MC; Thuong, NT; Valery, JM | 1 |
| Krecmerova, M; Röling, A; Rosemeyer, H; Seela, F | 1 |
| Brown, DB; Miskimins, WK | 1 |
| Crisp, B; Herberman, RB; Krause, D; Ortaldo, JR; Schmidt, A; Silverman, RH | 1 |
| Manzini, G; Quadrifoglio, F; van Boom, JH; van der Marel, GA; Xodo, LE; Yathindra, N | 1 |
| Davies, LC; Harrap, KR; Orr, RM; Powles, RL; Stock, JA; Taylor, GA | 1 |
| Barrie, SE; Davies, LC; Harrap, KR; Orr, RM; Stock, JA | 1 |
| Jaworska, M; Lesnikowski, ZJ; Stec, WJ | 1 |
| Hecht, SM; Jäger, A; Levy, MJ | 1 |
| Ghomi, M; Letellier, R; Taillandier, E | 1 |
| Altona, C; van Beuzekom, AA; van Boom, JH; van den Elst, H; van den Hoogen, YT; van der Marel, GA | 1 |
| Cormier, JF; Ogilvie, KK | 1 |
| Shapiro, HS | 1 |
| Hearst, JE; Shi, YB | 1 |
| Gaffney, BL; Gao, X; Jones, RA; Riddle, RR; Senior, M | 1 |
| Grollman, AP; Horwitz, SB; Takeshita, M | 1 |
| Kozlov, IA; Ledneva, RK; Lvova, TN; Tatarskaya, RI | 1 |
| Laipis, PJ; Levine, AJ | 1 |
| Bourgaux, P | 1 |
| Sternglanz, R; Wang, HF | 1 |
| Cowie, CH; Li, LH | 1 |
| Chirigos, MA; Chirikjian, JG; Irwin, RD; Massicot, JG; Papas, TS; Pry, TW | 1 |
| Odom, DG; Oró, J; Stephen-Sherwood, E | 1 |
| Wilt, FH; Wu, RS | 1 |
| Gait, MJ; Jones, AS; Walker, RT | 1 |
| Birnboim, HC; Straus, NA | 1 |
| Bernardi, G; Ehrlich, SD; Laval, J; Paoletti, C; Thiery, JP | 1 |
| Bernardi, G; Bertazzoni, U; Ehrlich, SD | 2 |
| DeLarco, J; Guroff, G | 1 |
| Edge, MD; Hodgson, A; Jones, AS; Walker, RT | 1 |
| Séquin, U | 1 |
| Anderson, CW; Eigner, J | 1 |
| De Clercq, E | 1 |
| Crea, R; Dinkelspiel, K; Manzini, G; Quadrifoglio, F; Vasser, M | 1 |
| Hanawalt, PC; Lewis, RJ | 1 |
| Morden, KM; Pardi, A; Patel, DJ; Tinoco, I | 1 |
| Chattopadhyaya, R; Dickerson, RE; Ikuta, S | 1 |
| Cramer, F; Dabkowski, W; McLaughlin, LW; Michalski, J; Piel, N; Skrzypczynski, Z | 1 |
| Altona, C; Mellema, JR; van Boom, JH; van der Marel, GA; van der Woerd, R | 1 |
| Breslauer, KJ; Broka, C; Dallas, J; Itakura, K; Kozlowski, SA; Marky, LA; Patel, DJ; Rice, JA | 1 |
| Elmblad, A; Josephson, S; Palm, G | 1 |
| Reese, CB; Ubasawa, A | 1 |
| Reese, CB; Zard, L | 1 |
| Levitskiĭ, EL | 1 |
| Hozumi, T; Itakura, K; Miyake, T; Miyoshi, K | 1 |
| Connolly, BA; Nikiforov, TT; Shaw, WV; Thomas, CD | 1 |
| Elbaggari, A; Jayaraman, K; Marshall, HB; McGrath, MS; Ojwang, J; Rando, RF | 1 |
| Garovoy, MR; Huey, B; Hunt, CA; Hwang, DG; Lantz, M; Li, Y; Lui, GM; Tam, S; Weiss, TL | 1 |
| Fennewald, SM; Mustain, S; Ojwang, J; Rando, RF | 1 |
| Gruenwedel, DW | 1 |
| Durland, RH; Jayaraman, K; Myrick, MA; Rao, TS; Rayford, J; Revankar, GR; Seth, DM; Singh, P; Tinsley, JH | 1 |
| Bonneil, E; Merle, L; Merle, Y; Sági, J; Szemzö, A | 1 |
| Dosanjh, MK; Eritja, R; Fabrega, C; Singer, B; Sinha, ND | 1 |
| Cheng, X; Hofstadler, SA; Smith, RD; Wu, Q | 1 |
| Gotfredsen, CH; Jacobsen, JP; Wengel, J | 1 |
| Agrawal, S; Iadarola, PL; Temsamani, J; Zhao, Q | 1 |
| Brown, T; Davison, A; McClean, J; Rao, MV | 1 |
| Atwal, D; Eller, MS; Gilchrest, BA; Maeda, T; Magnoni, C | 1 |
| Al-Irani, N; Branche, R; Doré, JF; Franchi, J; Marteau, C; Ozturk, M; Pedeux, R; Pellicier, F | 1 |
| Balow, G; Boyode, B; Guzaev, A; Manoharan, M; Tivel, KL | 1 |
| Kim, BH; Kim, SJ; Lee, JY | 1 |
| Bologna, JC; Imbach, JL; Morvan, F; Rayner, B; Tosquellas, G | 1 |
| Lin, C; Middleton, PJ; Pietrzkowski, Z; Wang, G | 1 |
| Kulińska, K; Kuliński, T; Stawiński, J | 1 |
| Greenberg, MM; Sambandam, A | 1 |
| Pfundheller, HM; Wengel, J | 1 |
| Jenkins, CL; Mannino, SJ; Raines, RT | 1 |
| Cruz, PD; Dougherty, I; Eller, M; Gilchrest, BA; Gleason, MJ; Leverkus, M; Yaar, M | 1 |
| Doboszewski, B; Peterson, MA; Robins, MJ; Timoshchuk, VA | 1 |
| Gerchman, SE; Grollman, AP; Iden, CR; Kycia, JH; McTigue, MM; Rieger, RA | 1 |
| Greenberg, MM; Laval, J; Privezentzev, CV; Sambandam, A; Saparbaev, M | 1 |
| Grinstaff, MW; Hu, X; Lee, SJ; Smith, GD; Sykora, M | 1 |
| Brès, JC; Imbach, JL; Lefebvre, I; Morvan, F; Pompon, A; Vasseur, JJ | 1 |
| An, H; Cook, PD; Maier, MA; Manoharan, M; Ross, BS; Wang, T | 1 |
| Bowers, MT; Bushnell, JE; Gidden, J | 1 |
| Berger, I; Spacková, N; Sponer, J | 1 |
| Orgel, LE; Wu, T | 1 |
| Richert, C; Rojas Stütz, JA | 1 |
| Garcia, GA; Kung, FL; Nonekowski, ST | 1 |
| Cunniffe, SM; David-Cordonnier, MH; Hickson, ID; O'Neill, P | 1 |
| Kawai, G; Kuwasaki, T; Miyano-Kurosaki, N; Suzuki, J; Takaku, H; Takeuchi, H | 1 |
| Nishio, M; Umezawa, Y | 1 |
| Eller, MS; Gilchrest, BA; Hadshiew, IM; Puri, N; Venna, SS | 1 |
| Boyd, A; Cuenoud, B; Majumdar, A; Martin, P; Miller, PS; Natt, F; Puri, N; Seidman, MM | 1 |
| Benner, SA; Held, HA | 1 |
| Burdzy, A; Noyes, KT; Sowers, LC; Valinluck, V | 1 |
| Detmer, I; Marx, A; Summerer, D | 1 |
| Kinoshita, E; Kinoshita-Kikuta, E; Koike, T | 1 |
| Bahr, MH; Chen, LS; Sheppard, TL | 1 |
| Budĕsínský, M; Králíková, S; Masojídková, M; Rosenberg, I | 1 |
| Barone, G; Erra, E; Giancola, C; Messere, A; Montesarchio, D; Petraccone, L; Piccialli, G | 1 |
| Efimtseva, EV; Herdewijn, P; Lescrinier, E; Mikhailov, SN; Nauwelaerts, K; Rozenski, J; Shelkunova, AA | 1 |
| Misra, K; Sanghvi, YS; Tripathi, S | 1 |
| Manoharan, M; Prakash, TP; Rajeev, KG | 1 |
| Cooper, MA; Hickman, DT; King, PM; Micklefield, J; Morral, J; Tan, TH | 1 |
| Gimautdinova, OI; Panin, LE; Tuzikov, FV | 1 |
| Bradbury, J | 1 |
| Arctander, P; Eriksen, J; Jacobsen, N; Jeffares, DC; Kauppinen, S; Nielsen, PS; Ohlsson, H | 1 |
| Epstein, DM; Iranzo, O; Khalili, H; Morrow, JR | 1 |
| Boado, RJ; Bryant, J; Charles, A; Pardridge, WM; Zhang, Y; Zhang, YF | 1 |
| Bryant-Friedrich, AC | 1 |
| Acharya, P; Chattopadhyaya, J; Cheruku, P; Gohil, S; Plashkevych, O; Pradeepkumar, PI | 1 |
| Davis, HL; Jurk, M; Krieg, AM; McCluskie, MJ; Payette, P; Samulowitz, U; Schetter, C; Vollmer, J; Weeratna, RD | 1 |
| Ferrara, L; Kmiec, EB; Parekh-Olmedo, H | 1 |
| Biondi, A; Cartron, G; Cazzaniga, G; Cittera, E; D'Apolito, M; Golay, J; Introna, M; Onofri, C; Paolucci, P; Zelante, L | 1 |
| Heckel, A; Mayer, G | 1 |
| Balaz, M; Benedetti, M; Berova, N; Holmes, AE; Proni, G | 1 |
| Kozelka, J; Sletten, E; Vinje, J | 1 |
| Dohno, C; Saito, I | 1 |
| Benner, SA; Sismour, AM | 1 |
| Seio, K; Sekine, M; Utagawa, E | 1 |
| Shaw, BR; Wang, JX | 1 |
| Gryaznov, S; Pongracz, K; Zielinska, D | 1 |
| Brieba, LG; Ellenberger, T; Kim, TW; Kool, ET | 1 |
| Lee, JS; Lindegaard, D; Wengel, J; Wood, DO | 1 |
| Cho, Y; Kool, ET | 1 |
| Doi, Y; Fujiwara, Y; Hitomi, K; Ide, H; Iwai, S; Katafuchi, A; Tainer, JA | 1 |
| Okamoto, I; Seio, K; Sekine, M | 1 |
| Christensen, MS; Kirchhoff, C; Mikkelsen, BH; Nielsen, KE; Nielsen, P; Ostergaard, K; Pedersen, SL; Petersen, M; Sharma, PK; Sørensen, AM | 1 |
| Daneshfar, R; Klassen, JS | 1 |
| Di Pasquale, F; Liebmann, M; Marx, A | 1 |
| Aso, M; Fukuda, M; Suemune, H; Usui, K | 1 |
| Hara, K; Inoue, H; Kitamura, M | 1 |
| Doi, Y; Hitomi, K; Iwai, S; Tainer, JA | 1 |
| Hitomi, K; Iwai, S; Todo, T; Yamamoto, J | 1 |
| Bryant-Friedrich, AC; Hitt, AL; Lahoud, GA | 1 |
| Huang, Z; Jiang, J; Salon, J; Sheng, J | 1 |
| Engstrom, JU; Kmiec, EB | 1 |
| Barchi, JJ; Maderia, M; Marquez, VE; Shenoy, S; Van, QN | 1 |
| Caton-Williams, J; Chen, G; Huang, Z; Jiang, J; Salon, J; Sheng, J | 1 |
| Barman, J; Chattopadhyaya, J; Pathmasiri, W; Plashkevych, O; Srivastava, P; Wenska, M | 1 |
| Gogoi, K; Gunjal, AD; Kumar, VA; Phalgune, UD | 1 |
| Christensen, MS; Madsen, CM; Nielsen, P | 1 |
| Atoyan, RY; Botchkarev, VA; Eller, MS; Gilchrest, BA; Sargsyan, A; Sharov, AA | 1 |
| Ahlborn, C; Richert, C; Siegmund, K | 1 |
| Chattopadhyaya, J | 1 |
| Higashida, R; Kawanaka, T; Oka, N; Wada, T | 1 |
| Harada, Y; Imanishi, T; Kodama, T; Mitsuoka, Y; Obika, S; Osaki, T; Sugaya, K | 1 |
| Brown, T; Durand, A | 1 |
| Noronha, AM; Wilds, CJ; Xu, F | 1 |
| Huang, Z; Sheng, J | 1 |
| Enderlin, G; Nielsen, P | 1 |
| Enderlin, G; Kumar, S; Nielsen, P; Sharma, PK | 1 |
| Gokhale, S; Kumar, VA | 1 |
| Haynes, C; Hughesman, CB; Turner, RF | 1 |
| Kobayashi, K; Tagawa, S; Yamagami, R | 1 |
| Chu, X; Harris, DC; Jayawickramarajah, J | 1 |
| Lavrik, O; Petruseva, I; Saintomé, C; Salas, TR | 1 |
| Brown, T; El-Sagheer, AH | 1 |
| Leroy, JL | 1 |
| Hassan, AE; Huang, Z; Jiang, J; Sheng, J; Zhang, W | 1 |
| Cheng, TL; Tseng, WL; Yu, CJ | 1 |
| Carell, T; Fazio, D; Glas, AF; Heil, K; Kaya, E; Maul, MJ; Schneider, S | 1 |
| Ball, LM; Chen, X; Collins, LB; Gold, A; Lu, K; Swenberg, JA; Ye, W; Zhou, L | 1 |
| Huang, Y; Liu, S; Liu, X; Luo, Q; Tang, D; Wang, F; Wang, R; Wu, D; Wu, G | 1 |
| Huang, Z; Zhang, W | 1 |
| Geacintov, NE; Shafirovich, V; Yun, BH | 1 |
| Cosstick, R; Gaynor, JW | 1 |
| Karran, P; Macpherson, P; Reelfs, O; Ren, X; Xu, YZ; Young, AR | 1 |
| Cech, TR; Nandakumar, J | 1 |
| Bednarek, E; Bocian, W; Hyz, K; Kawęcki, R; Kozerski, L; Misior, A; Sitkowski, J | 1 |
| Hou, P; Long, Y; Wang, J; Zhao, J; Zhou, F | 1 |
| Komatsu, Y; Mizutani, R; Nikaido, O; Ohtsuka, E; Sato, K; Satow, Y; Yokoyama, H | 1 |
| Chen, T; Clark, T; DiMattia, D; Dullea, R; Kreeger, J; Little, J; Liu, M; Moshinsky, D; Qian, J; Roy, M; Salatto, C; Sciabola, S; Stanton, R; Walters, E; Weng, Y | 1 |
| Brown, T; El-Sagheer, AH; Shelbourne, M | 1 |
| Dolinnaya, NG; Kubareva, EA; Oretskaya, TS; Romanova, EA; Trikin, RM | 1 |
| Hari, Y; Obika, S; Osawa, T | 1 |
| Miller, PS; Noronha, AM; Sun, G; Wilds, CJ | 1 |
| Köstler, K; Malecki, E; Montilla-Martinez, M; Rosemeyer, H; Werz, E | 1 |
| Chaput, JC; Yu, H; Zhang, S | 1 |
| Dey, R; Gokhale, SS; Gunjal, AD; Gupta, S; Kumar, VA; Pillai, B; Soni, K | 1 |
| Dugovic, B; Leumann, CJ | 1 |
| Granqvist, L; Virta, P | 1 |
| Golkar, N; Samani, SM; Tamaddon, AM; Tavakoli, S | 1 |
| Dwight, TA; Jung, ME; Seth, PP; Swayze, EE; Vigant, F; Østergaard, ME | 1 |
| Guan, Y; Shang, H; Tong, Z; Zhao, B; Zhao, G | 1 |
| Fujimura, Y; Hari, Y; Kugimiya, A; Mitsuoka, Y; Obika, S; Waki, R; Yamamoto, T | 1 |
| Clark, MA; Keefe, AD; Litovchick, A | 1 |
| Ames, DM; Jian, Y; Li, L; Ouyang, H | 1 |
| Ghuman, H; MacRenaris, KW; Meade, TJ; Modo, M; Nicholls, FJ; Rotz, MW | 1 |
| Kinbara, K; Muraoka, T; Sugimoto, N; Tateishi-Karimata, H | 1 |
| Chen, Q; Georgiadis, M | 1 |
| Aviñó, A; Eritja, R; Fàbrega, C; Gargallo, R; Mazzini, S; Morales, JC; Peñalver, P | 1 |
| Nilsson, L; Villa, A; Xu, Y | 1 |
| Bell, DR; Chen, YA; Cheng, SY; Imphean, DM; Liu, YL; Llanos, MF; Obliosca, JM; Petty, JT; Ren, P; Yeh, HC | 1 |
| Richert, C; Walter, TJ | 1 |
| Benhida, R; Coulon, S; Désert, A; Drujon, T; Gérard-Hirne, T; Guérineau, V; Guianvarc'h, D; Michel, BY; Sachon, E; Saintomé, C; Thiebaut, F | 1 |
| Dohi, M; Hari, Y; Ito, Y; Kim, H; Obika, S; Osawa, T; Saijo, M; Shoji, M | 1 |
| Hisamatsu, S; Kanamori, T; Muto, K; Nishizawa, S; Ohkubo, A; Watanabe, R | 1 |
| Hari, Y; Ito, Y; Jang, YJ; Kawaguchi, M; Osawa, T | 1 |
| Ueda, H; Ueno, Y | 1 |
| Chandela, A; Chano, T; Katsuzaki, Y; Tsukimura, R; Ueno, Y | 1 |
| Forough, M; Persil Çetinkol, Ö; Usta, HM | 1 |
| Chandela, A; Ueda, H; Ueno, Y | 1 |
| Aoyama, H; Obika, S; Osawa, T; Yano, N | 1 |
| Eyberg, J; Richert, C; Ringenberg, M | 1 |
2 review(s) available for thymidine and oligonucleotides
| Article | Year |
|---|---|
The chemical effects of nucleic acid alkylation and their relation to mutagenesis and carcinogenesis.
Topics: Adenosine; Alkylating Agents; Alkylation; Binding Sites; Carcinogens; Cytidine; Diazonium Compounds; DNA; Guanosine; Hydrogen-Ion Concentration; Kinetics; Molecular Conformation; Mutagens; Oligonucleotides; Polynucleotides; RNA; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Thymidine; Uridine | 1975 |
Thymidine glycol: the effect on DNA molecular structure and enzymatic processing.
Topics: Base Pairing; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Directed DNA Polymerase; Endonucleases; Escherichia coli; Humans; Nucleic Acid Conformation; Oligonucleotides; Protein Biosynthesis; Stereoisomerism; Thymidine; Transcription, Genetic | 2013 |
206 other study(ies) available for thymidine and oligonucleotides
| Article | Year |
|---|---|
The prebiotic synthesis of deoxythymidine oligonucleotides. III. Acid salt reactions.
Topics: Ammonia; Binding Sites; Biological Evolution; Chemical Phenomena; Chemistry; Hydrogen-Ion Concentration; Oligodeoxyribonucleotides; Oligonucleotides; Phosphoric Diester Hydrolases; Salts; Thymidine | 1976 |
The effect of antibiotics on the T4 polynucleotide ligase catalyzed template dependent polymerization of oligodeoxythymidylates.
Topics: Anti-Bacterial Agents; Coliphages; Ethidium; Kinetics; Netropsin; Oligonucleotides; Oligoribonucleotides; Poly dA-dT; Polynucleotide Ligases; Templates, Genetic; Thymidine | 1979 |
Geometry of the dry-state oligomerization of 2',3'-cyclic phosphates.
Topics: Chemical Phenomena; Chemistry; Nucleotides, Cyclic; Oligonucleotides; Stereoisomerism; Thymidine; Uracil Nucleotides | 1979 |
Thymidine photoproducts of non-cyclobutane type as a crucial event in the conformation of UV-irradiated DNA.
Topics: Chromatography, Paper; Circular Dichroism; Cyclobutanes; Formates; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; Photochemistry; Poly dA-dT; Polydeoxyribonucleotides; Pyrimidine Dimers; Thymidine; Ultraviolet Rays | 1979 |
Regulation of fungal ribonucleotide reductase by unusual dinucleotides.
Topics: Cell Division; Cell Line; Escherichia coli; Fungi; Kinetics; Oligonucleotides; Oligoribonucleotides; Ribonucleotide Reductases; Species Specificity; Structure-Activity Relationship; Thymidine | 1976 |
Different nuclease activities in competent and noncompetent Bacillus subtilis.
Topics: Bacillus subtilis; Carbon Radioisotopes; Cell Wall; Centrifugation, Density Gradient; Deoxyribonucleases; DNA, Bacterial; Edetic Acid; Escherichia coli; Exonucleases; Mutation; Nucleic Acid Denaturation; Oligonucleotides; Protoplasts; Thymidine; Thymidine Monophosphate; Thymine; Transformation, Genetic; Tritium; Tryptophan | 1975 |
Structure of thymidylyl-3',5'-deoxyadenosine.
Topics: Adenosine; Nucleic Acid Conformation; Oligonucleotides; Thymidine; X-Ray Diffraction | 1976 |
The investigation of peptide-oligodeoxythymidylic acid interactions using template chromatography.
Topics: Binding Sites; Chromatography, Affinity; Oligodeoxyribonucleotides; Oligonucleotides; Oligopeptides; Protein Binding; Proteins; Temperature; Templates, Genetic; Thymidine | 1975 |
Sugar modified oligonucleotides: synthesis, nuclease resistance and base pairing of oligodeoxynucleotides containing 1-(4'-thio-beta-D-ribofuranosyl)-thymine.
Topics: Animals; Base Composition; Cattle; Drug Stability; Indicators and Reagents; Magnetic Resonance Spectroscopy; Nucleic Acid Denaturation; Oligonucleotides; Phosphoric Diester Hydrolases; Spleen; Substrate Specificity; Thionucleosides; Thymidine | 1992 |
In vitro toxicological evaluation of ISIS 1082, a phosphorothioate oligonucleotide inhibitor of herpes simplex virus.
Topics: Antiviral Agents; Base Sequence; Cell Division; Cell Survival; DNA; DNA-Directed DNA Polymerase; HeLa Cells; Humans; Kinetics; Molecular Sequence Data; Oligodeoxyribonucleotides, Antisense; Oligonucleotides; Organophosphorus Compounds; RNA; Simplexvirus; Thionucleotides; Thymidine | 1992 |
Synthesis and physicochemical properties of oligonucleotides built with either alpha-L or beta-L nucleotides units and covalently linked to an acridine derivative.
Topics: Acridines; Adenosine; Exonucleases; Nucleic Acid Conformation; Nucleic Acid Hybridization; Oligonucleotides; Poly T; Poly U; Single-Strand Specific DNA and RNA Endonucleases; Spectrophotometry; Temperature; Thymidine; Uridine | 1991 |
Solid-phase synthesis of oligo(2'-deoxyxylonucleotides) and PCR amplification of base-modified DNA fragments.
Topics: Adenosine; Base Sequence; DNA; DNA Restriction Enzymes; DNA-Directed DNA Polymerase; Molecular Sequence Data; Molecular Structure; Oligonucleotides; Organophosphonates; Polymerase Chain Reaction; Restriction Mapping; Substrate Specificity; Taq Polymerase; Thymidine; Xylose | 1991 |
Analysis of cis-acting promoter elements using microinjected synthetic oligonucleotides.
Topics: Animals; Base Sequence; Cell Cycle; Cell Line; DNA; Fibroblasts; Gene Expression; Mice; Microinjections; Molecular Sequence Data; Oligonucleotides; Promoter Regions, Genetic; Receptors, Transferrin; S Phase; Thymidine; Transcription, Genetic; Tritium | 1990 |
Involvement of the 2'-5' A pathway in the augmentation of natural killer activity.
Topics: 2',5'-Oligoadenylate Synthetase; Calcium; Cytotoxicity, Immunologic; DNA; Enzyme Induction; Humans; Interferons; Killer Cells, Natural; Oligonucleotides; T-Lymphocytes; Thymidine | 1987 |
The left-handed Z-DNA conformation in oligodeoxynucleotides containing different amounts of AT base pairs: a far UV circular dichroism study.
Topics: Adenine; Base Composition; Base Sequence; Circular Dichroism; DNA; Nucleic Acid Conformation; Oligonucleotides; Spectrophotometry, Ultraviolet; Thermodynamics; Thymidine | 1989 |
Inhibition of human leukaemic thymidylate kinase and L1210 ribonucleotide reductase by dinucleotides of adenosine and thymidine and their phosphonate analogues.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Humans; Kinetics; Leukemia L1210; Leukemia, Myeloid, Acute; Nucleoside-Phosphate Kinase; Oligonucleotides; Organophosphonates; Phosphotransferases; Ribonucleoside Diphosphate Reductase; Ribonucleotide Reductases; Thymidine | 1988 |
Dinucleotide analogues as inhibitors of thymidine kinase, thymidylate kinase, and ribonucleotide reductase.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Chemical Phenomena; Chemistry; Dinucleoside Phosphates; Leukemia L1210; Nucleoside-Phosphate Kinase; Oligonucleotides; Phosphotransferases; Ribonucleotide Reductases; Structure-Activity Relationship; Thymidine; Thymidine Kinase; Thymine Nucleotides | 1988 |
Stereoselective synthesis of P-homochiral oligo(thymidine methanephosphonates).
Topics: Circular Dichroism; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Oligonucleotides; Organothiophosphorus Compounds; Stereoisomerism; Thymidine | 1988 |
Oligonucleotide N-alkylphosphoramidates: synthesis and binding to polynucleotides.
Topics: Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Circular Dichroism; Deoxyadenosines; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Nucleic Acid Probes; Oligonucleotides; Organophosphorus Compounds; Polynucleotides; Stereoisomerism; Thymidine | 1988 |
Interpretation of DNA vibration modes. II--The adenosine and thymidine residues involved in oligonucleotides and polynucleotides.
Topics: Adenosine; DNA; Models, Molecular; Nucleic Acid Conformation; Oligonucleotides; Polynucleotides; Spectrum Analysis, Raman; Thymidine; Vibration | 1987 |
Extra thymidine stacks into the d(CTGGTGCGG).d(CCGCCCAG) duplex. An NMR and model-building study.
Topics: Base Composition; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleic Acid Conformation; Oligonucleotides; Software; Structure-Activity Relationship; Thermodynamics; Thymidine | 1988 |
Synthesis of hexanucleotide analogues containing diisopropylsilyl internucleotide linkages.
Topics: Circular Dichroism; Indicators and Reagents; Nucleic Acid Conformation; Oligonucleotides; Silanes; Silicon; Structure-Activity Relationship; Thymidine | 1988 |
Studies on the nucleotide arrangement in DNA. Estimation of sequence isomers in pyrimidine deoxyribo-oligonucleotides.
Topics: Animals; Base Sequence; Cattle; Deamination; DNA; Hydroxylamines; Oligonucleotides; Phosphorylation; Pyrimidine Nucleotides; Stereoisomerism; Thymidine | 1987 |
Wavelength dependence for the photoreactions of DNA-psoralen monoadducts. 1. Photoreversal of monoadducts.
Topics: Cross-Linking Reagents; DNA, Single-Stranded; Electrophoresis; Ficusin; Furans; Furocoumarins; Oligonucleotides; Protein Conformation; Thymidine; Trioxsalen; Ultraviolet Rays | 1987 |
Methylation of thymine residues during oligonucleotide synthesis.
Topics: Alkylation; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Methylation; Oligodeoxyribonucleotides; Oligonucleotides; Organophosphates; Thymidine; Thymine | 1985 |
Bleomycin, an inhibitor of vaccinia virus replication.
Topics: Animals; Antiviral Agents; Bleomycin; Centrifugation, Zonal; DNA; DNA-Directed RNA Polymerases; DNA, Viral; HeLa Cells; Male; Mice; Oligonucleotides; RNA, Messenger; RNA, Viral; Thymidine; Tritium; Uridine; Vaccinia; Vaccinia virus; Virus Replication | 1974 |
The substrate specificity of exonuclease A5.
Topics: Actinomyces; Acylation; Adenine Nucleotides; Chromatography; Cyanates; Cytosine Nucleotides; Deoxyribonucleotides; Glycols; Guanine Nucleotides; Kinetics; Nitrophenols; Oligonucleotides; Phosphates; Phosphoric Diester Hydrolases; Resorcinols; Spectrophotometry; Structure-Activity Relationship; Thymidine; Thymine Nucleotides | 1973 |
DNA replication in SV40-infected cells. IX. The inhibition of a gap-filling step during discontinuous synthesis of SV40 DNA.
Topics: Animals; Cell Line; Cell-Free System; Centrifugation, Density Gradient; Coliphages; Culture Techniques; DNA Nucleotidyltransferases; DNA Repair; DNA Replication; DNA, Viral; Escherichia coli; Haplorhini; Hydroxyurea; Kidney; Models, Chemical; Nucleic Acid Hybridization; Oligonucleotides; Phosphorus Radioisotopes; Polynucleotide Ligases; Simian virus 40; Thymidine; Tritium; Virus Cultivation | 1973 |
On the origin of oligomer forms of polyoma DNA.
Topics: Carbon Radioisotopes; Centrifugation, Density Gradient; Cycloheximide; DNA, Viral; Nucleic Acid Conformation; Oligonucleotides; Polyomavirus; Puromycin; Thymidine; Tritium | 1973 |
Thymine-labelled deoxyoligonucleotide involved in DNA chain growth in Bacillus subtilis.
Topics: Bacillus subtilis; Centrifugation, Density Gradient; Chromatography, Gel; Deoxyribonucleases; Deoxyribonucleotides; DNA, Bacterial; Exonucleases; Hydrolysis; Oligonucleotides; Phosphoric Diester Hydrolases; Pronase; Sodium Hydroxide; Thymidine; Thymine; Tritium | 1974 |
Biochemical effects of ellipticine on leukemia L1210 cells.
Topics: Alkaloids; Animals; Antineoplastic Agents; Carbazoles; Carbon Radioisotopes; Depression, Chemical; DNA Nucleotidyltransferases; DNA-Directed RNA Polymerases; DNA, Neoplasm; Leucine; Leukemia L1210; Methyl Ethers; Micrococcus; Neoplasm Proteins; Oligonucleotides; Phosphotransferases; Pyridines; RNA, Neoplasm; Salmon; Temperature; Thymidine; Thymidine Kinase; Time Factors; Tritium; Ultracentrifugation; Uridine | 1974 |
Effect of chemically modified 70S RNA from avian myeloblastosis virus (AMV) upon the activity of AMV DNA polymerase.
Topics: Acetaldehyde; Avian Leukosis Virus; Carbon Radioisotopes; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry; DNA Nucleotidyltransferases; Oligonucleotides; RNA, Viral; Spectrometry, Fluorescence; Templates, Genetic; Thymidine; Transcription, Genetic; Uridine | 1974 |
The prebiotic synthesis of deoxythymidine oligonucleotides.
Topics: Biological Evolution; Carboxylic Acids; Cyanates; Imidazoles; Models, Chemical; Oligonucleotides; Phosphates; Polymers; Temperature; Thymidine | 1974 |
The synthesis and degradation of RNA containing polyriboadenylate during sea urchin embryogeny.
Topics: Adenine Nucleotides; Adenosine; Animals; Carbon Radioisotopes; Cell Fractionation; Cell Nucleus; Centrifugation, Density Gradient; Chromatography; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Formaldehyde; Hydroxyurea; Kinetics; Mitosis; Oligonucleotides; Polynucleotides; Ribonucleases; RNA; Sea Urchins; Spectrophotometry; Thymidine; Thymine Nucleotides; Tritium | 1974 |
Synthetic-analogues of polynucleotides XII. Synthesis of thymidine derivatives containing an oxyacetamido- or an oxyformamido-linkage instead of a phosphodiester group.
Topics: Acetamides; Formamides; Methods; Oligonucleotides; Thymidine | 1974 |
Long pyrimidine tracts of L-cell DNA: localization to repeated DNA.
Topics: Animals; Base Sequence; Chromatography; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Female; HeLa Cells; Humans; Hydroxyapatites; L Cells; Mice; Nucleic Acid Denaturation; Nucleic Acid Renaturation; Oligonucleotides; Polynucleotides; Pyrimidine Nucleotides; Thymidine; Tritium | 1974 |
Studies on the specificity of an acid deoxyribonuclease from Helix aspersa (Müll.).
Topics: Animals; Cattle; Chromatography, DEAE-Cellulose; Deoxyadenosines; Deoxycytidine; Deoxyribonucleases; Deoxyribonucleotides; DNA; Guanosine; Kinetics; Nucleic Acid Conformation; Oligonucleotides; Phosphates; Snails; Spectrophotometry, Ultraviolet; Spleen; Swine; Thymidine; Thymus Gland | 1973 |
The specificity of pancreatic deoxyribonuclease.
Topics: Absorption; Animals; Cattle; Deoxyadenosines; Deoxycytidine; Deoxyribonucleases; DNA, Bacterial; Escherichia coli; Guanosine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Macromolecular Substances; Nucleic Acid Conformation; Oligonucleotides; Pancreas; Solubility; Spectrum Analysis; Thymidine; Thymus Gland | 1973 |
The specificity of Escherichia coli endonuclease I.
Topics: Absorption; Animals; Cattle; Chromatography, DEAE-Cellulose; Deoxyadenosines; Deoxycytidine; DNA, Bacterial; Endonucleases; Escherichia coli; Guanosine; Hydrogen-Ion Concentration; Kinetics; Nucleic Acid Conformation; Oligonucleotides; Solubility; Species Specificity; Spectrum Analysis; Thymidine; Thymus Gland | 1973 |
The synthesis of RNA which binds to oligo(dT)-cellulose by brain in vivo and in vitro.
Topics: Adenine; Age Factors; Animals; Brain; Cellulose; Centrifugation, Density Gradient; Cerebral Cortex; Chemical Phenomena; Chemistry; Cytidine; In Vitro Techniques; Male; Oligonucleotides; Rats; RNA; Thymidine; Tritium | 1972 |
Synthetic analogues of polynucleotides. 8. Analogues of oligonucleotides containing carboxymethylthymidine.
Topics: Chemical Phenomena; Chemistry; Decarboxylation; Methylation; Oligonucleotides; Polynucleotides; Thymidine; Uridine | 1972 |
Nucleosides and nucleotides. 5. The stereochemistry of oligonucleotides consisting of 2'-deoxy-alpha-D-ribosides, a study with Drieding stereomodels.
Topics: Adenine Nucleotides; Base Sequence; Cytosine Nucleotides; Deoxyribonucleosides; Guanine Nucleotides; Models, Structural; Nucleic Acid Conformation; Oligonucleotides; Stereoisomerism; Thymidine; Thymine Nucleotides | 1973 |
Breakdown and exclusion of superinfecting T-even bacteriophage in Escherichia coli.
Topics: Centrifugation, Density Gradient; Coliphages; Cyanides; Deoxyribonucleases; DNA Viruses; DNA, Viral; Escherichia coli; Leucine; Molecular Weight; Mutation; Nucleic Acid Denaturation; Oligonucleotides; Phosphates; Phosphorus Radioisotopes; Rifampin; RNA, Viral; Solubility; Streptomycin; Thymidine; Tritium; Viral Interference; Viral Proteins | 1971 |
Design of nucleoside, oligonucleotide and polynucleotide analogues as antiviral agents.
Topics: Adenosine; Antiviral Agents; Deoxycytidine; DNA-Directed DNA Polymerase; DNA-Directed RNA Polymerases; Nucleosides; Oligonucleotides; Polynucleotides; RNA-Directed DNA Polymerase; Structure-Activity Relationship; Thymidine; Viruses | 1982 |
Conformational stability of alternating d (CG) oligomers in high salt solution.
Topics: Chlorides; Circular Dichroism; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Drug Stability; Lithium; Lithium Chloride; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; Osmolar Concentration; Sodium Chloride; Thymidine | 1981 |
Ligation of oligonucleotides by pyrimidine dimers--a missing 'link' in the origin of life?
Topics: Endonucleases; Escherichia coli; Oligonucleotides; Pyrimidine Dimers; T-Phages; Thymidine; Ultraviolet Rays | 1982 |
Kinetics for exchange of imino protons in the d(C-G-C-G-A-A-T-T-C-G-C-G) double helix and in two similar helices that contain a G . T base pair, d(C-G-T-G-A-A-T-T-C-G-C-G), and an extra adenine, d(C-G-C-A-G-A-A-T-T-C-G-C-G).
Topics: Adenine; Guanine; Kinetics; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; Protons; Thymidine | 1982 |
The kinetics of phosphotriester condensation reactions on solid support.
Topics: Indicators and Reagents; Kinetics; Oligonucleotides; Organophosphates; Temperature; Thermodynamics; Thymidine | 1984 |
Synthesis and reactions of a nucleoside derivative of phosphoric sulfonic anhydride. Studies related to the mechanisms of coupling reactions in the chemical synthesis of oligodeoxyribonucleotides by phosphotriester procedures.
Topics: Chemical Phenomena; Chemistry; Indicators and Reagents; Magnetic Resonance Spectroscopy; Oligodeoxyribonucleotides; Oligonucleotides; Organothiophosphorus Compounds; Structure-Activity Relationship; Thymidine | 1984 |
Proton NMR study and conformational analysis of d(CGT), d(TCG) and d(CGTCG) in aqueous solution. The effect of a dangling thymidine and of a thymidine mismatch on DNA mini-duplexes.
Topics: Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; Solutions; Structure-Activity Relationship; Thermodynamics; Thymidine | 1984 |
Structure, dynamics, and energetics of deoxyguanosine . thymidine wobble base pair formation in the self-complementary d(CGTGAATTCGCG) duplex in solution.
Topics: Base Composition; Base Sequence; Calorimetry, Differential Scanning; Deoxyguanosine; Fourier Analysis; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; Thermodynamics; Thymidine | 1982 |
Synthesis of mixed oligodeoxyribonucleotides following the solid phase method.
Topics: Chromatography, High Pressure Liquid; Indicators and Reagents; Methods; Oligodeoxyribonucleotides; Oligonucleotides; Thymidine | 1982 |
Nature of side-reactions in oligonucleotide synthesis involving arenesulphonyl derivatives of 3-nitro-1,2,4-triazole and related condensing agents.
Topics: Adenosine; Cytidine; Deoxyguanosine; Indicators and Reagents; Magnetic Resonance Spectroscopy; Methods; Oligonucleotides; Structure-Activity Relationship; Sulfones; Thymidine; Triazoles | 1980 |
Some observations relating to the oximate ion promoted unblocking of oligonucleotide aryl esters.
Topics: Indicators and Reagents; Methods; Oligonucleotides; Oximes; Thymidine | 1981 |
[Age and features of DNA replication in intact white rat liver].
Topics: Age Factors; Animals; DNA Replication; DNA, Single-Stranded; Female; Liver; Liver Regeneration; Oligonucleotides; Rats; Thymidine; Time Factors | 1980 |
Solid-phase synthesis of polynucleotides. II. Synthesis of polythymidylic acids by the block coupling phosphotriester method.
Topics: Indicators and Reagents; Methods; Oligodeoxyribonucleotides; Oligonucleotides; Poly T; Polydeoxyribonucleotides; Resins, Plant; Spectrophotometry; Thymidine | 1980 |
Determination of sequence specificity between a plasmid replication initiator protein and the origin of replication.
Topics: Bacterial Proteins; Base Sequence; Binding Sites; Binding, Competitive; Cross-Linking Reagents; DNA Damage; DNA Replication; DNA Topoisomerases, Type I; DNA-Binding Proteins; Models, Genetic; Molecular Sequence Data; Oligonucleotides; Plasmids; Protein Binding; Replication Origin; Thymidine | 1995 |
Inhibition of human immunodeficiency virus type 1 activity in vitro by oligonucleotides composed entirely of guanosine and thymidine.
Topics: Animals; Antibodies, Monoclonal; Base Sequence; Binding, Competitive; CD4 Antigens; Cell Division; Cell Line; Giant Cells; Guanosine; HIV Core Protein p24; HIV Envelope Protein gp120; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Sequence Data; Oligonucleotides; Peptide Fragments; Reverse Transcriptase Inhibitors; Thymidine; Vero Cells | 1994 |
Suppression of interferon-gamma induction of MHC class II and ICAM-1 by a 26-base oligonucleotide composed of deoxyguanosine and deoxythymidine.
Topics: Base Sequence; Blotting, Northern; Cell Line; Deoxyguanosine; HLA-DP Antigens; HLA-DR Antigens; Humans; Intercellular Adhesion Molecule-1; Interferon-gamma; Molecular Sequence Data; Oligonucleotides; Thymidine | 1994 |
Inhibition of herpes simplex virus in culture by oligonucleotides composed entirely of deoxyguanosine and thymidine.
Topics: Animals; Antiviral Agents; Base Sequence; Cell Division; Chlorocebus aethiops; Cytopathogenic Effect, Viral; Deoxyguanosine; DNA, Viral; Herpesvirus 1, Human; Herpesvirus 2, Human; Microbial Sensitivity Tests; Molecular Sequence Data; Oligonucleotides; RNA, Viral; Structure-Activity Relationship; Thymidine; Vero Cells | 1995 |
Effect of Hg(II) on the spectroscopic properties of DNA bases: circular dichroism of deoxyadenosine and thymidine monomers and dimers.
Topics: Circular Dichroism; Deoxyadenosines; DNA; Mercury Compounds; Nucleic Acid Conformation; Oligonucleotides; Perchlorates; Structure-Activity Relationship; Thymidine | 1994 |
Binding of T and T analogs to CG base pairs in antiparallel triplexes.
Topics: Base Composition; Base Sequence; Cytosine; Drug Stability; Guanine; Molecular Sequence Data; Molecular Structure; Oligonucleotides; Oxygen; Structure-Activity Relationship; Thymidine; Thymine | 1994 |
Acyclic oligonucleotide analogues.
Topics: Adenine; Adenine Nucleotides; Circular Dichroism; Deoxyribonucleotides; DNA Polymerase I; DNA Primers; Drug Stability; Glycerol; Models, Molecular; Oligonucleotides; Phosphatidic Acids; Phosphoric Diester Hydrolases; Snake Venoms; Temperature; Thymidine; Thymine; Thymine Nucleotides | 1995 |
Synthesis and properties of oligonucleotides containing the mutagenic base O4-benzylthymidine.
Topics: Base Composition; Base Sequence; Circular Dichroism; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotides; Organophosphorus Compounds; Thymidine | 1995 |
Specific metal-oligonucleotide binding studied by high resolution tandem mass spectrometry.
Topics: Cyclotrons; DNA Adducts; Flame Ionization; Fourier Analysis; Gas Chromatography-Mass Spectrometry; Metals; Oligonucleotides; Thymidine | 1996 |
Synthesis and properties of alpha- and beta-oligodeoxynucleotides containing alpha- and beta-1-(2-O-methyl-D-arabino-furanosyl)thymine.
Topics: Arabinonucleosides; Isomerism; Magnetic Resonance Spectroscopy; Oligonucleotides; Thymidine | 1996 |
Modulation of oligonucleotide-induced immune stimulation by cyclodextrin analogs.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Adjuvants, Immunologic; Animals; Base Sequence; beta-Cyclodextrins; Cell Division; Cyclodextrins; Drug Interactions; Immune System; Immunoglobulin M; In Vitro Techniques; Lymphocyte Activation; Male; Mice; Oligonucleotides; Spleen; Splenomegaly; Thymidine | 1996 |
Synthesis of oligonucleotides labelled with 2,4-dinitrophenyl groups at thymidine sites.
Topics: Chromatography, High Pressure Liquid; Dinitrobenzenes; Models, Chemical; Oligonucleotides; Thymidine | 1996 |
Enhancement of DNA repair in human skin cells by thymidine dinucleotides: evidence for a p53-mediated mammalian SOS response.
Topics: Cells, Cultured; DNA Damage; DNA Repair; Humans; Infant, Newborn; Keratinocytes; Oligonucleotides; Skin Physiological Phenomena; Thymidine; Tumor Suppressor Protein p53; Ultraviolet Rays | 1997 |
Thymidine dinucleotides induce S phase cell cycle arrest in addition to increased melanogenesis in human melanocytes.
Topics: Cell Division; DNA Fragmentation; Humans; Melanins; Melanocytes; Oligonucleotides; S Phase; Thymidine; Tumor Cells, Cultured | 1998 |
Synthesis of 14 C-radiolabeled oligonucleotides with a novel phosphoramidite reagent.
Topics: Carbon Radioisotopes; Indicators and Reagents; Isotope Labeling; Models, Molecular; Molecular Conformation; Molecular Structure; Oligonucleotides; Organophosphorus Compounds; Thymidine | 1998 |
Design and synthesis of isoxazole and isoxazoline linkage for replacement of nucleotide phosphodiester.
Topics: Drug Design; Isoxazoles; Oligonucleotides; Thymidine | 1998 |
First synthesis of alternating SATE-phosphotriester/phosphodiester prooligonucleotides on solid support.
Topics: Animals; Cell Extracts; Esterases; Half-Life; Liver; Oligonucleotides; Swine; Thymidine | 1998 |
Biophysical and biochemical properties of oligodeoxy-nucleotides containing 4'-C- and 5'-C-substituted thymidines.
Topics: Antigens, CD; Humans; Kinetics; Models, Chemical; Oligonucleotides; Receptors, Interleukin; Receptors, Interleukin-8A; Ribonuclease H; Thymidine | 1999 |
Hydration of C-H groups in natural dithymidine nucleotide and its methylphosphonate analogues.
Topics: Carbon; Crystallography; Hydrogen; Hydrogen Bonding; Models, Molecular; Oligonucleotides; Thionucleotides; Thymidine; Water | 1998 |
The effects of 5R-5,6-dihydro-5-hydroxythymidine on duplex DNA stability and structure.
Topics: DNA; Mass Spectrometry; Models, Chemical; Nucleic Acid Conformation; Oligonucleotides; Temperature; Thermodynamics; Thymidine | 1999 |
Oligonucleotides containing 4'-C-aminomethyl-2'-modified thymidines show increased binding affinity towards DNA and RNA.
Topics: Base Sequence; DNA; Nucleic Acid Conformation; Oligonucleotides; RNA; Thymidine | 1999 |
Chemical mechanism of DNA cleavage by the homing endonuclease I-PpoI.
Topics: Catalysis; Circular Dichroism; DNA; Electrophoresis, Agar Gel; Endodeoxyribonucleases; Enzyme Activation; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Oligonucleotides; Thymidine | 1999 |
Thymidine dinucleotides inhibit contact hypersensitivity and activate the gene for tumor necrosis factor alpha1.
Topics: Animals; Dermatitis, Contact; Drug Stability; Gene Expression Regulation; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oligonucleotides; RNA, Messenger; Thymidine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2000 |
Glucose-derived 3'-(carboxymethyl)-3'-deoxyribonucleosides and 2', 3'-lactones as synthetic precursors for amide-linked oligonucleotide analogues.
Topics: Deoxyadenosines; Glucose; Indicators and Reagents; Lactones; Magnetic Resonance Spectroscopy; Oligonucleotides; Thymidine | 2000 |
Characterization of a cross-linked DNA-endonuclease VIII repair complex by electrospray ionization mass spectrometry.
Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Cross-Linking Reagents; Deoxyribonuclease (Pyrimidine Dimer); DNA; DNA Repair; Endodeoxyribonucleases; Glycols; Hydrolysis; Indicators and Reagents; Mass Spectrometry; Molecular Sequence Data; Oligonucleotides; Peptides; Thymidine; Trypsin | 2000 |
AlkA protein is the third Escherichia coli DNA repair protein excising a ring fragmentation product of thymine.
Topics: 5' Untranslated Regions; Animals; Base Pairing; DNA Fragmentation; DNA Glycosylases; DNA Repair; Escherichia coli; Humans; Kinetics; Mutagenesis, Site-Directed; Mutagens; N-Glycosyl Hydrolases; Nucleic Acid Heteroduplexes; Oligonucleotides; Rats; Substrate Specificity; Thymidine; Thymine; Urea | 2000 |
Automated solid-phase synthesis and photophysical properties of oligodeoxynucleotides labeled at 5'-aminothymidine with Ru(bpy)2(4-m-4'-cam-bpy)2+.
Topics: DNA; Oligonucleotides; Organometallic Compounds; Photochemistry; Ruthenium; Spectroscopy, Fourier Transform Infrared; Thymidine | 2000 |
Kinetics study of the biotransformation of an oligonucleotide prodrug in cells extract by matrix-assisted laser desorption-ionization time-of-flight mass spectrometry.
Topics: Biotransformation; Cell Extracts; Oligonucleotides; Prodrugs; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thymidine | 2001 |
Synthesis of novel 3'-C-methylene thymidine and 5-methyluridine/cytidine H-phosphonates and phosphonamidites for new backbone modification of oligonucleotides.
Topics: Anti-Infective Agents; Antineoplastic Agents; Cytidine; Oligonucleotides; Oligonucleotides, Antisense; Organophosphonates; Thymidine; Uridine | 2001 |
Gas-phase conformations and folding energetics of oligonucleotides: dTG- and dGT-.
Topics: Base Pairing; Gases; Guanidine; Mass Spectrometry; Molecular Conformation; Oligonucleotides; Thermodynamics; Thymidine | 2001 |
Structural dynamics and cation interactions of DNA quadruplex molecules containing mixed guanine/cytosine quartets revealed by large-scale MD simulations.
Topics: Base Sequence; Cations, Monovalent; Computer Simulation; Cytosine; DNA; Guanine; Models, Chemical; Models, Molecular; Nucleic Acid Conformation; Oligonucleotides; Potassium Chloride; Sodium Chloride; Solutions; Thermodynamics; Thymidine | 2001 |
Nonenzymatic template-directed synthesis on hairpin oligonucleotides. 3. Incorporation of adenosine and uridine residues.
Topics: Adenine; Adenosine; Base Composition; Base Sequence; Cytidine Monophosphate; Cytosine; Guanine; Guanosine Monophosphate; Molecular Sequence Data; Oligonucleotides; Polymers; Templates, Genetic; Thymidine; Thymine; Uridine | 1992 |
A steroid cap adjusts the selectivity and accelerates the rates of nonenzymatic single nucleotide extensions of an oligonucleotide.
Topics: Base Pair Mismatch; Cholic Acid; Deoxyadenosines; Deoxyguanosine; DNA; Kinetics; Nucleotides; Oligonucleotides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Templates, Genetic; Thymidine | 2001 |
The Escherichia coli tRNA-guanine transglycosylase can recognize and modify DNA.
Topics: Base Sequence; Catalysis; Deoxyuridine; DNA; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Kinetics; Molecular Sequence Data; Nucleic Acid Conformation; Oligonucleotides; Pentosyltransferases; Protein Binding; RNA; Thymidine; Uracil | 2002 |
Efficiency of incision of an AP site within clustered DNA damage by the major human AP endonuclease.
Topics: Adjuvants, Immunologic; Base Sequence; Binding Sites; Carbon-Oxygen Lyases; Catalytic Domain; Deoxyribonuclease IV (Phage T4-Induced); DNA Damage; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA, Complementary; Dose-Response Relationship, Drug; Escherichia coli; Escherichia coli Proteins; Guanosine; Humans; Kinetics; Models, Genetic; Molecular Sequence Data; Oligonucleotides; Oxygen; Protein Binding; Sequence Homology, Nucleic Acid; Thymidine | 2002 |
Inhibition of human immunodeficiency virus type 1 activity in vitro by a new self-stabilized oligonucleotide with guanosine-thymidine quadruplex motifs.
Topics: Giant Cells; Guanosine; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Oligonucleotides; Phosphates; Thymidine | 2002 |
Thymine-methyl/pi interaction implicated in the sequence-dependent deformability of DNA.
Topics: Crystallography, X-Ray; DNA; DNA Methylation; Hydrogen Bonding; Nucleic Acid Conformation; Oligonucleotides; Thymidine | 2002 |
Induction of apoptosis by telomere 3' overhang-specific DNA.
Topics: 3' Flanking Region; Apoptosis; Base Sequence; Cell Cycle Proteins; Cell Division; Cell Transformation, Neoplastic; Cellular Senescence; DNA; DNA Damage; DNA-Binding Proteins; Dose-Response Relationship, Drug; E2F Transcription Factors; E2F1 Transcription Factor; Eukaryotic Cells; Genes, Tumor Suppressor; Humans; Jurkat Cells; Nuclear Proteins; Oligonucleotides; S Phase; Telomere; Thymidine; Transcription Factors; Tumor Protein p73; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Up-Regulation | 2002 |
Minimum number of 2'-O-(2-aminoethyl) residues required for gene knockout activity by triple helix forming oligonucleotides.
Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Cytosine; DNA; Electroporation; Gene Targeting; Hot Temperature; Hypoxanthine Phosphoribosyltransferase; Nucleic Acid Conformation; Oligonucleotides; Ribose; Thymidine | 2002 |
Challenging artificial genetic systems: thymidine analogs with 5-position sulfur functionality.
Topics: Deoxyuracil Nucleotides; DNA Primers; DNA-Directed DNA Polymerase; Oligonucleotides; Polymerase Chain Reaction; Sulfur; Templates, Genetic; Thymidine | 2002 |
Synthesis of stable-isotope enriched 5-methylpyrimidines and their use as probes of base reactivity in DNA.
Topics: Base Sequence; Carbon Isotopes; Deuterium; DNA; DNA Probes; Gas Chromatography-Mass Spectrometry; Hydroxyl Radical; Nitrogen Isotopes; Oligonucleotides; Pyrimidines; Reactive Oxygen Species; Thymidine; Thymine | 2002 |
DNA minor groove hydration probed with 4'-alkylated thymidines.
Topics: Alkylation; DNA; Molecular Probes; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligonucleotides; Temperature; Thymidine; Water | 2002 |
A novel procedure for simple and efficient genotyping of single nucleotide polymorphisms by using the Zn2+-cyclen complex.
Topics: Base Sequence; Binding Sites; Cyclams; DNA; DNA, Single-Stranded; Electrophoresis, Polyacrylamide Gel; Genotype; Heterocyclic Compounds; Heterozygote; Humans; Models, Chemical; Molecular Sequence Data; Oligonucleotides; Polymorphism, Single Nucleotide; Sodium Channels; Thymidine; Zinc Compounds | 2002 |
Effects of 8-chlorodeoxyadenosine on DNA synthesis by the Klenow fragment of DNA polymerase I.
Topics: Deoxyadenosines; DNA; DNA Polymerase I; Escherichia coli; Oligonucleotides; Thymidine | 2003 |
Study on reactivity and protection of the alpha-hydroxyphosphonate moiety in 5'-nucleotide analogues: formation of the 3'-O-P-C(OH)-C4' internucleotide linkage.
Topics: Models, Chemical; Molecular Structure; Nucleic Acid Conformation; Nucleotides; Oligodeoxyribonucleotides; Oligonucleotides; Organophosphonates; Pyrimidine Dimers; Stereoisomerism; Thymidine | 2003 |
Physico-chemical studies of a DNA triplex containing a new ferrocenemethyl-thymidine residue in the third strand.
Topics: Calorimetry, Differential Scanning; Chemical Phenomena; Chemistry, Physical; Circular Dichroism; DNA; Ferrous Compounds; Hydrogen-Ion Concentration; Metallocenes; Models, Molecular; Oligonucleotides; Thermodynamics; Thymidine | 2003 |
Synthesis and properties of phosphorylated 3'-O-beta-D-ribofuranosyl-2'-deoxythymidine.
Topics: Magnetic Resonance Spectroscopy; Mass Spectrometry; Oligonucleotides; Organophosphorus Compounds; Phosphorylation; Thymidine | 2003 |
Synthesis and application of bis (tert-butyl)-1-methyl pyrenyl-silyl chloride as a 5'-hydroxyl protecting group for nucleosides and as a fluorescent purification handle in oligonucleotide synthesis.
Topics: Base Sequence; Fluorescent Dyes; Nucleosides; Oligonucleotides; Pyrenes; Thymidine | 2002 |
2'-modified-2-thiothymidine oligonucleotides.
Topics: Animals; Base Sequence; DNA, Complementary; Drug Stability; Hot Temperature; Oligonucleotides; Phosphoric Diester Hydrolases; RNA, Complementary; Snake Venoms; Thymidine | 2003 |
Design, synthesis, conformational analysis and nucleic acid hybridisation properties of thymidyl pyrrolidine-amide oligonucleotide mimics (POM).
Topics: Base Pairing; Biomimetic Materials; Drug Design; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Oligonucleotides; Osmolar Concentration; Pyrrolidines; Surface Plasmon Resonance; Temperature; Thymidine | 2003 |
Tetrahydrocortisol-apolipoprotein A-I complex specifically interacts with eukaryotic DNA and GCC elements of genes.
Topics: Animals; Apolipoprotein A-I; Base Sequence; DNA; Genes; Hepatocytes; Humans; Leucine; Liver; Molecular Sequence Data; Oligonucleotides; Protein Biosynthesis; Rats; Rats, Wistar; Scattering, Radiation; Tetrahydrocortisol; Thymidine; X-Rays | 2003 |
An extra defence against skin cancer?
Topics: Administration, Topical; Animals; Cell Transformation, Neoplastic; Mice; Oligonucleotides; Risk Factors; Skin Neoplasms; Thymidine; Ultraviolet Rays | 2004 |
Direct isolation of poly(A)+ RNA from 4 M guanidine thiocyanate-lysed cell extracts using locked nucleic acid-oligo(T) capture.
Topics: Actins; Animals; Caenorhabditis elegans; Cell Extracts; Chromatography, Affinity; DNA Probes; Drug Resistance, Neoplasm; Genes, Fungal; Genes, MDR; Guanidines; Humans; K562 Cells; Ligands; Magnetics; Microspheres; Nucleic Acid Denaturation; Oligonucleotides; Oligonucleotides, Antisense; Poly A; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Saccharomyces cerevisiae; Sodium Chloride; Thiocyanates; Thymidine; Vincristine | 2004 |
Recruitment of divalent metal ions by incorporation of 4-thio-2'-deoxythymidine or 4-thio-2'-deoxyuridine into DNA.
Topics: Cadmium; Cations, Divalent; DNA; Metals, Heavy; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligonucleotides; Temperature; Thionucleosides; Thiouridine; Thymidine | 2004 |
Intravenous RNA interference gene therapy targeting the human epidermal growth factor receptor prolongs survival in intracranial brain cancer.
Topics: Animals; Base Sequence; Blotting, Western; Brain; Brain Neoplasms; Calcium; Cell Line, Tumor; DNA; Dose-Response Relationship, Drug; Endocytosis; ErbB Receptors; Genetic Therapy; Humans; Immunohistochemistry; Ligands; Liposomes; Mice; Microscopy, Confocal; Models, Biological; Molecular Sequence Data; Neoplasm Transplantation; Oligonucleotides; Plasmids; Polyethylene Glycols; RNA Interference; Signal Transduction; Thymidine; Time Factors; Treatment Outcome | 2004 |
Generation of a C-3'-thymidinyl radical in single-stranded oligonucleotides under anaerobic conditions.
Topics: Base Sequence; Chromatography, High Pressure Liquid; DNA; Oligonucleotides; Organophosphonates; Oxidation-Reduction; Photochemistry; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thymidine | 2004 |
Synthesis, physicochemical and biochemical studies of 1',2'-oxetane constrained adenosine and guanosine modified oligonucleotides, and their comparison with those of the corresponding cytidine and thymidine analogues.
Topics: Adenosine; Base Sequence; Circular Dichroism; Cytidine; Deoxyribonuclease I; Ethers, Cyclic; Guanosine; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Nucleic Acid Heteroduplexes; Oligonucleotides; Proto-Oncogene Mas; Ribonuclease H; RNA; Thermodynamics; Thymidine | 2004 |
Oligodeoxynucleotides lacking CpG dinucleotides mediate Toll-like receptor 9 dependent T helper type 2 biased immune stimulation.
Topics: Animals; Antibody Formation; B-Lymphocytes; Base Sequence; Cell Division; Chemokine CXCL10; Chemokines, CXC; Cytokines; Dendritic Cells; DNA-Binding Proteins; Female; Humans; Interferons; Interleukin-10; Interleukin-6; Mice; Mice, Inbred BALB C; NF-kappa B; Oligodeoxyribonucleotides; Oligonucleotides; Receptors, Cell Surface; Spleen; Th2 Cells; Thymidine; Toll-Like Receptor 9 | 2004 |
Enhanced oligonucleotide-directed gene targeting in mammalian cells following treatment with DNA damaging agents.
Topics: Cell Count; Cell Line; DNA; DNA Damage; DNA Repair; DNA Replication; Electroporation; Etoposide; Flow Cytometry; Gene Targeting; Humans; Hydroxyurea; Mutagenesis, Site-Directed; Mutagens; Mutation; Oligonucleotides; Recombination, Genetic; Thymidine; Up-Regulation | 2004 |
Rituximab induces different but overlapping sets of genes in human B-lymphoma cell lines.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20; Antineoplastic Agents; Apoptosis; Cell Adhesion; Cell Line, Tumor; Daclizumab; DNA Primers; DNA, Complementary; Dose-Response Relationship, Drug; Dose-Response Relationship, Immunologic; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Immunoglobulin G; In Situ Nick-End Labeling; Lymphoma; Lymphoma, B-Cell; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Oligonucleotide Array Sequence Analysis; Oligonucleotides; Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Rituximab; RNA; RNA, Complementary; Thymidine; Time Factors; Transcription Factor AP-1; Transcriptional Activation; Up-Regulation | 2005 |
Light regulation of aptamer activity: an anti-thrombin aptamer with caged thymidine nucleobases.
Topics: Antithrombins; Blood Coagulation; DNA, Single-Stranded; Humans; Kinetics; Light; Models, Molecular; Oligonucleotides; Photochemistry; Thymidine | 2005 |
Porphyrin substituted phosphoramidites: new building blocks for porphyrin-oligonucleotide syntheses.
Topics: Molecular Conformation; Oligonucleotides; Organophosphorus Compounds; Porphyrins; Thymidine | 2005 |
Influence of dT20 and [d(AT)10]2 on cisplatin hydrolysis studied by two-dimensional [1H,15N] HMQC NMR spectroscopy.
Topics: Adenine; Antineoplastic Agents; Cisplatin; Dinucleoside Phosphates; DNA; Hydrogen; Hydrogen-Ion Concentration; Hydrolysis; Magnetic Resonance Spectroscopy; Molecular Structure; Nitrogen Isotopes; Oligonucleotides; Poly T; Thermodynamics; Thymidine | 2005 |
Discrimination of single-nucleotide alterations by G-specific fluorescence quenching.
Topics: Adenine; Base Pair Mismatch; Biosensing Techniques; Fluorescence; Fluorescent Dyes; Guanine; Nucleotides; Oligonucleotides; Pyrenes; Spectrometry, Fluorescence; Thymidine | 2005 |
The use of thymidine analogs to improve the replication of an extra DNA base pair: a synthetic biological system.
Topics: Base Pairing; Cytosine; DNA Polymerase I; DNA Primers; DNA Replication; Guanine; Oligonucleotides; Polymerase Chain Reaction; Thymidine; Thymine Nucleotides | 2005 |
A new protecting group for the 5'-hydroxyl group having O-S single bond oxidatively cleavable under mild conditions.
Topics: Catalysis; Furans; Hydroxides; Hydroxyl Radical; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Biology; Oligonucleotides; Oxygen; Sulfur; Thymidine | 2005 |
Synthesis of 5-(1-propynyl)-2'-deoxyuridine 5'-(alpha-P-borano)triphosphate and kinetic characterization as a substrate for mmlv reverse transcriptase.
Topics: Boron; Boron Compounds; DNA; DNA Primers; HIV Reverse Transcriptase; Kinetics; Models, Chemical; Moloney murine leukemia virus; Nucleotides; Oligonucleotides; Polyphosphates; Protein Isoforms; Pyrimidines; RNA-Directed DNA Polymerase; Thymidine; Thymine Nucleotides; Uridine; Uridine Triphosphate | 2005 |
A new approach to oligonucleotide N3'-->P5' phosphoramidate building blocks.
Topics: Base Composition; Guanosine; Models, Chemical; Molecular Biology; Nitrogen; Nucleic Acid Conformation; Nucleosides; Oligonucleotides; Phosphorus; Thymidine | 2005 |
Functional evidence for a small and rigid active site in a high fidelity DNA polymerase: probing T7 DNA polymerase with variably sized base pairs.
Topics: Bacteriophage T7; Base Pairing; Binding Sites; DNA; DNA Polymerase I; DNA-Directed DNA Polymerase; Escherichia coli; Genetic Techniques; Kinetics; Models, Chemical; Oligonucleotides; Protein Binding; Templates, Genetic; Thymidine | 2006 |
Electron injection from the side of an M-DNA duplex.
Topics: Base Sequence; Cations, Divalent; Chlorides; DNA; Electron Transport; Electrons; Fluorescein; Hydrogen-Ion Concentration; Metals; Nucleic Acid Conformation; Oligonucleotides; Spectrometry, Fluorescence; Temperature; Thymidine; Zinc Compounds | 2006 |
Enzymatic synthesis of fluorescent oligomers assembled on a DNA backbone.
Topics: DNA; DNA Nucleotidylexotransferase; Fluorescence; Molecular Structure; Oligonucleotides; Pyrenes; Sensitivity and Specificity; Spectrometry, Fluorescence; Thymidine | 2006 |
Synthesis and characterization of oligonucleotides containing 2'-fluorinated thymidine glycol as inhibitors of the endonuclease III reaction.
Topics: Deoxyribonuclease (Pyrimidine Dimer); Enzyme Inhibitors; Escherichia coli Proteins; Isomerism; Oligonucleotides; Organophosphorus Compounds; Substrate Specificity; Thymidine; Viral Proteins | 2006 |
Triplex forming ability of oligonucleotides containing 2'-O-methyl-2-thiouridine or 2-thiothymidine.
Topics: Base Sequence; Nucleic Acid Conformation; Oligonucleotides; Thiouridine; Thymidine; Transition Temperature | 2006 |
A cyclic dinucleotide with a four-carbon 5'-C-to-5'-C connection; synthesis by RCM, NMR-examination and incorporation into secondary nucleic acid structures.
Topics: Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Oligonucleotides; Thermodynamics; Thymidine | 2006 |
Thermal decomposition of multiply charged T-rich oligonucleotide anions in the gas phase. Influence of internal solvation on the arrhenius parameters for neutral base loss.
Topics: Base Sequence; Computer Simulation; Gases; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Molecular Sequence Data; Oligonucleotides; Phase Transition; Sequence Analysis, DNA; Solvents; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Static Electricity; Temperature; Thymidine | 2006 |
A new photoactive building block for investigation of DNA backbone interactions: photoaffinity labeling of human DNA polymerase beta.
Topics: DNA; DNA Polymerase beta; Humans; Molecular Structure; Oligonucleotides; Photoaffinity Labels; Protein Binding; Thymidine; Ultraviolet Rays | 2006 |
Synthesis of oligonucleotide containing 4'-o-nitrobenzyloxythymidine and its reactivity.
Topics: Chromatography, High Pressure Liquid; Oligonucleotides; Photochemistry; Thymidine | 2004 |
Synthesis and hybridization studies on oligonucleotide-metal complex conjugates.
Topics: Base Pair Mismatch; Base Sequence; Metals; Molecular Sequence Data; Nucleic Acid Heteroduplexes; Nucleic Acid Hybridization; Oligonucleotides; Pyridines; Thermodynamics; Thymidine; Transition Temperature | 2004 |
Synthesis of oligonucleotides containing 2'-fluorinated thymidine glycol as mechanism-based inhibitors of endonuclease III.
Topics: Crystallography, X-Ray; Endodeoxyribonucleases; Enzyme Inhibitors; Oligonucleotides; Organophosphorus Compounds; Thymidine | 2005 |
Synthesis of oligonucleotides containing the Dewar valence isomer of the (6-4) photoproduct and their application to (6-4) photolyase studies.
Topics: Chromatography, High Pressure Liquid; Deoxyribodipyrimidine Photo-Lyase; Dinucleoside Phosphates; Heterocyclic Compounds, 4 or More Rings; Oligonucleotides; Organophosphorus Compounds; Stereoisomerism; Substrate Specificity; Thymidine; Ultraviolet Rays | 2006 |
Aerobic fate of the C-3'-thymidinyl radical in single-stranded DNA.
Topics: Aerobiosis; Chromatography, High Pressure Liquid; DNA, Single-Stranded; Oligonucleotides; Organophosphonates; Oxidation-Reduction; Photochemistry; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thymidine | 2006 |
Synthesis of a 2'-Se-thymidine phosphoramidite and its incorporation into oligonucleotides for crystal structure study.
Topics: Base Sequence; Crystallography, X-Ray; DNA; Models, Molecular; Molecular Conformation; Oligonucleotides; Organophosphorus Compounds; Organoselenium Compounds; Thymidine | 2007 |
Manipulation of cell cycle progression can counteract the apparent loss of correction frequency following oligonucleotide-directed gene repair.
Topics: Cell Cycle; Cell Division; Cells, Cultured; Cellular Senescence; DNA Repair; DNA Replication; Genetic Therapy; Humans; Oligonucleotides; Thymidine; Time Factors | 2007 |
Biophysical studies of DNA modified with conformationally constrained nucleotides: comparison of 2'-exo (north) and 3'-exo (south) 'locked' templates.
Topics: Calorimetry, Differential Scanning; Carbohydrate Conformation; Circular Dichroism; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; Oligonucleotides, Antisense; RNA; Thermodynamics; Thymidine | 2007 |
Oxygen replacement with selenium at the thymidine 4-position for the Se base pairing and crystal structure studies.
Topics: Base Pairing; Crystallography, X-Ray; DNA; Nucleic Acid Conformation; Oligonucleotides; Organophosphorus Compounds; Oxygen; Selenium; Thymidine | 2007 |
Five- and six-membered conformationally locked 2',4'-carbocyclic ribo-thymidines: synthesis, structure, and biochemical studies.
Topics: Base Sequence; Carbohydrates; Humans; Molecular Structure; Nucleic Acid Denaturation; Oligonucleotides; Oligonucleotides, Antisense; Organophosphorus Compounds; Ribonucleases; Serum; Thymidine | 2007 |
Synthesis and RNA binding selectivity of oligonucleotides modified with five-atom thioacetamido nucleic acid backbone structures.
Topics: DNA; DNA, Complementary; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Nucleic Acids; Oligonucleotides; RNA; Thioacetamide; Thymidine; Ultraviolet Rays | 2007 |
Synthesis and modelling of DNA junction and minor groove zipper motifs incorporating the double-headed nucleoside 5'(S)-C-(thymine-1-ylmethyl)thymidine.
Topics: Chemistry, Pharmaceutical; DNA; Models, Chemical; Models, Molecular; Nucleic Acid Conformation; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Nucleosides; Nucleotides; Oligodeoxyribonucleotides; Oligonucleotides; Temperature; Thermodynamics; Thymidine; Thymine | 2007 |
Oligonucleotide treatment increases eumelanogenesis, hair pigmentation and melanocortin-1 receptor expression in the hair follicle.
Topics: Animals; Dinucleoside Phosphates; Gene Transfer Techniques; Hair Color; Hair Follicle; Intramolecular Oxidoreductases; Melanins; Melanocytes; Membrane Glycoproteins; Mice; Mice, Inbred C3H; Monophenol Monooxygenase; Oligonucleotides; Oxidoreductases; Pigmentation; Receptor, Melanocortin, Type 1; Signal Transduction; Thymidine | 2007 |
Isostable DNA.
Topics: Adenine; Base Pairing; DNA; Drug Stability; Fluorescence; Oligonucleotide Array Sequence Analysis; Oligonucleotides; Thermodynamics; Thymidine | 2007 |
Conformationally-2',4'-locked Aza-ENA and carbocyclic ribo-thymidine.
Topics: Nucleic Acid Conformation; Oligonucleotides; Oligonucleotides, Antisense; Ribonuclease H; Thymidine | 2007 |
Nucleoside H-boranophosphonates: synthesis and properties of a new class of nucleotide analogs.
Topics: Boron Compounds; Oligonucleotides; Organophosphonates; Thymidine | 2007 |
Synthesis and properties of a 2'-deoxy analogue of trans-3',4'-BNA with an S-type sugar conformation.
Topics: Bridged-Ring Compounds; Carbohydrate Conformation; DNA; Nucleic Acid Hybridization; Nucleosides; Oligonucleotides; RNA; Thymidine | 2007 |
Synthesis and properties of oligonucleotides containing a cholesterol thymidine monomer.
Topics: Cholesterol; Fluorescence; Hydrogen-Ion Concentration; Nucleic Acid Denaturation; Oligonucleotides; Organophosphorus Compounds; Thymidine | 2007 |
Synthesis and characterization of DNA containing an N1-2'-deoxyinosine-ethyl-N3-thymidine interstrand cross-link: a structural mimic of the cross-link formed by 1,3-bis-(2-chloroethyl)-1-nitrosourea.
Topics: Carcinogens; Carmustine; Chromatography, High Pressure Liquid; Circular Dichroism; Cross-Linking Reagents; DNA; DNA Repair; Indicators and Reagents; Inosine; Models, Molecular; Nucleic Acid Denaturation; Oligonucleotides; Thymidine; Ultraviolet Rays | 2008 |
Synthesis of a 4-selenothymidine phosphoramidite and incorporation into oligonucleotides.
Topics: Amides; Crystallography, X-Ray; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Oligonucleotides; Phosphoric Acids; Selenium; Spectrometry, Mass, Electrospray Ionization; Thymidine | 2008 |
Synthesis of 6'-branched locked nucleic acid by a radical TEMPO-scavanged stereoselective mercury cyclization.
Topics: Azides; Cyclic N-Oxides; Cyclization; Free Radical Scavengers; Mercury; Models, Chemical; Oligonucleotides; Stereoisomerism; Thymidine; Triazoles | 2008 |
Synthesis of 3'- and 6'-functionalized locked nucleic acid (LNA) analogues.
Topics: Oligonucleotides; Thymidine | 2008 |
Iso-thioacetamido nucleic acids (isoTANA): synthesis and DNA binding studies of lyxo/ribo oligonucleotides.
Topics: DNA; Oligonucleotides; RNA; Thymidine | 2008 |
Stability and mismatch discrimination of DNA duplexes containing 2,6-diaminopurine and 2-thiothymidine locked nucleic acid bases.
Topics: 2-Aminopurine; Base Pair Mismatch; Calorimetry, Differential Scanning; DNA; Oligonucleotide Probes; Oligonucleotides; Spectrophotometry, Ultraviolet; Thermodynamics; Thymidine | 2008 |
Formation of spectral intermediate G-C and A-T anion complex in duplex DNA studied by pulse radiolysis.
Topics: Base Pairing; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA; Hydrogen-Ion Concentration; Oligonucleotides; Pulse Radiolysis; Thymidine | 2008 |
DNA-small molecule chimera with responsive protein-binding ability.
Topics: Benzamidines; Carbonic Anhydrases; DNA; Fluorescein; Fluorescence Polarization; Models, Molecular; Nucleic Acid Conformation; Oligonucleotides; Phenylthiourea; Protein Conformation; Proteins; Recombinant Fusion Proteins; Serum Albumin; Streptavidin; Thymidine; Trypsin | 2008 |
Evidence for direct contact between the RPA3 subunit of the human replication protein A and single-stranded DNA.
Topics: Binding Sites; DNA-Binding Proteins; DNA, Single-Stranded; Humans; Oligonucleotides; Protein Binding; Protein Subunits; Replication Protein A; Thymidine | 2009 |
Synthesis and polymerase chain reaction amplification of DNA strands containing an unnatural triazole linkage.
Topics: DNA; DNA-Directed DNA Polymerase; Oligonucleotides; Polymerase Chain Reaction; Thymidine; Triazoles | 2009 |
The formation pathway of i-motif tetramers.
Topics: Cytidine; Hydrogen-Ion Concentration; Kinetics; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Oligonucleotides; Protons; Temperature; Thymidine | 2009 |
Synthesis and crystallographic analysis of 5-Se-thymidine DNAs.
Topics: Base Sequence; Crystallography, X-Ray; DNA; Hydrogen Bonding; Models, Molecular; Molecular Structure; Nucleic Acid Conformation; Oligonucleotides; Organophosphorus Compounds; Organoselenium Compounds; Selenium; Thymidine | 2009 |
Effects of Mn2+ on oligonucleotide-gold nanoparticle hybrids for colorimetric sensing of Hg2+: improving colorimetric sensitivity and accelerating color change.
Topics: Biosensing Techniques; Colorimetry; Fresh Water; Gold; Manganese; Mercury; Metal Nanoparticles; Oligonucleotides; Sensitivity and Specificity; Thymidine | 2009 |
DNA (6-4) photolyases reduce Dewar isomers for isomerization into (6-4) lesions.
Topics: Cytosine; Deoxyribodipyrimidine Photo-Lyase; DNA Damage; DNA Repair; DNA, Single-Stranded; Isomerism; Oligonucleotides; Pyrimidine Dimers; Thymidine | 2010 |
Structural characterization of formaldehyde-induced cross-links between amino acids and deoxynucleosides and their oligomers.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Formaldehyde; Formic Acid Esters; Nuclear Magnetic Resonance, Biomolecular; Nucleosides; Oligonucleotides; Oligopeptides; Spectroscopy, Fourier Transform Infrared; Tandem Mass Spectrometry; Thymidine | 2010 |
The formation of thymidine-based T-tetramers with remarkable structural and metal ion size effects.
Topics: Ions; Metals; Models, Molecular; Molecular Structure; Oligonucleotides; Spectrometry, Mass, Electrospray Ionization; Thymidine | 2011 |
Synthesis of the 5'-Se-thymidine phosphoramidite and convenient labeling of DNA oligonucleotide.
Topics: DNA; Molecular Structure; Oligonucleotides; Organoselenium Compounds; Thymidine | 2011 |
Generation of guanine-thymidine cross-links in DNA by peroxynitrite/carbon dioxide.
Topics: Alkaline Phosphatase; Animals; Bicarbonates; Carbon Dioxide; Cattle; Chromatography, High Pressure Liquid; DNA; Guanidines; Guanine; Hydrogen-Ion Concentration; Nitroimidazoles; Oligonucleotides; Oxidation-Reduction; Peroxynitrous Acid; Tandem Mass Spectrometry; Thymidine; Water | 2011 |
Dinucleotides containing 3'-S-phosphorothiolate linkages.
Topics: Antiviral Agents; Chemistry, Pharmaceutical; Dinucleoside Phosphates; Endonucleases; Hepatitis B; Hepatitis B virus; HIV; HIV Infections; Humans; Oligonucleotides; Organophosphorus Compounds; Phosphates; Phosphites; Spectrum Analysis; Thymidine | 2011 |
Identification of potentially cytotoxic lesions induced by UVA photoactivation of DNA 4-thiothymidine in human cells.
Topics: Animals; Cell Line; Cricetinae; DNA; DNA Damage; DNA Repair; Humans; Mutagenesis; Oligonucleotides; Pyrimidine Dimers; Reactive Oxygen Species; Skin; Thymidine; Ultraviolet Rays | 2011 |
DNA-induced dimerization of the single-stranded DNA binding telomeric protein Pot1 from Schizosaccharomyces pombe.
Topics: Carrier Proteins; Dimerization; DNA-Binding Proteins; DNA, Single-Stranded; Oligonucleotides; Protein Structure, Tertiary; Repetitive Sequences, Nucleic Acid; RNA; Schizosaccharomyces pombe Proteins; Shelterin Complex; Telomere; Telomere-Binding Proteins; Thymidine; Uridine | 2012 |
Genistein binding mode to doubly nicked dumbbell DNA. Dynamic and diffusion ordered NMR study.
Topics: Antineoplastic Agents; DNA; Genistein; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleic Acid Conformation; Oligonucleotides; Solutions; Thymidine | 2011 |
A thymidine-terminated molecular beacon for selective Hg2+ or sequence-specific DNA assay.
Topics: Base Sequence; Biological Assay; DNA; Hydrogen-Ion Concentration; Mercury; Molecular Probes; Oligonucleotides; Spectrometry, Fluorescence; Thymidine | 2012 |
Structure of the DNA (6-4) photoproduct dTT(6-4)TT in complex with the 64M-2 antibody Fab fragment implies increased antibody-binding affinity by the flanking nucleotides.
Topics: Antibodies, Monoclonal; Antibody Affinity; Binding Sites, Antibody; Crystallography, X-Ray; DNA Damage; Immunoglobulin Fab Fragments; Models, Molecular; Oligonucleotides; Pyrimidine Dimers; Thymidine; Ultraviolet Rays | 2012 |
Chemical modification study of antisense gapmers.
Topics: Adenosine; Animals; Base Sequence; Cell Line, Tumor; Cytidine; Gene Expression Regulation; Gene Knockdown Techniques; Guanosine; Humans; Kidney; Liver; Male; Mice; Mice, Inbred C57BL; Oligonucleotides; Oligonucleotides, Antisense; Oxazines; Receptors, Glucocorticoid; RNA, Messenger; Thymidine; Transfection; Transition Temperature | 2012 |
Fast and efficient DNA crosslinking and multiple orthogonal labelling by copper-free click chemistry.
Topics: Alkynes; Azides; Click Chemistry; Copper; Fluorescent Dyes; Nucleic Acid Conformation; Oligonucleotides; Thymidine | 2012 |
Synthesis and duplex-forming ability of oligonucleotides containing 4'-carboxythymidine analogs.
Topics: Carbohydrate Conformation; DNA, Complementary; Oligonucleotides; RNA, Complementary; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thymidine; Transition Temperature | 2012 |
Synthesis of building blocks and oligonucleotides with {T}N3-alkylene-N3{T} cross-links.
Topics: Alkylating Agents; Chromatography, Gel; DNA; DNA Repair; Oligonucleotides; Organophosphorus Compounds; Solid-Phase Synthesis Techniques; Thymidine | 2012 |
Nucleoterpenes of thymidine and 2'-deoxyinosine: synthons for a biomimetic lipophilization of oligonucleotides.
Topics: Biomimetic Materials; Carbocyanines; Inosine; Lipid Bilayers; Microscopy, Fluorescence; Oligonucleotides; Spectrometry, Fluorescence; Thymidine | 2013 |
Synthesis of threose nucleic acid (TNA) triphosphates and oligonucleotides by polymerase-mediated primer extension.
Topics: Cytidine; DNA Primers; DNA-Directed DNA Polymerase; Guanosine; Oligonucleotides; Polyphosphates; Tetroses; Thymidine | 2013 |
Detection and knockdown of microRNA-34a using thioacetamido nucleic acid.
Topics: Apoptosis; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Genes, myc; HEK293 Cells; Humans; MicroRNAs; Oligonucleotides; Thymidine; Tumor Suppressor Protein p53 | 2013 |
A 6′-fluoro-substituent in bicyclo-DNA increases affinity to complementary RNA presumably by CF–HC pseudohydrogen bonds.
Topics: Base Pairing; Bridged Bicyclo Compounds, Heterocyclic; Crystallography, X-Ray; DNA; Hydrogen Bonding; Hydrogenation; Magnetic Resonance Spectroscopy; Nucleosides; Oligonucleotides; RNA, Complementary; Static Electricity; Thermodynamics; Thymidine | 2014 |
4'-C-[(4-trifluoromethyl-1H-1,2,3-triazol-1-yl)methyl]thymidine as a sensitive (19)F NMR sensor for the detection of oligonucleotide secondary structures.
Topics: Base Sequence; DNA; HIV Long Terminal Repeat; HIV-1; Magnetic Resonance Spectroscopy; Oligonucleotides; Protein Structure, Secondary; RNA; Thymidine; Triazoles | 2014 |
Microencapsulation of (deoxythymidine)₂₀-DOTAP complexes in stealth liposomes optimized by Taguchi design.
Topics: Chemistry, Pharmaceutical; Drug Stability; Gene Transfer Techniques; Liposomes; Oligonucleotides; Particle Size; Thymidine | 2015 |
Synthesis and duplex-stabilizing properties of fluorinated N-methanocarbathymidine analogues locked in the C3'-endo conformation.
Topics: Models, Molecular; Molecular Conformation; Molecular Structure; Nucleic Acid Conformation; Oligonucleotides; Thymidine | 2014 |
2'-O-methyl nucleotide modified DNA substrates influence the cleavage efficiencies of BamHI and BglII.
Topics: Adenosine; Bacterial Proteins; Cytidine; Deoxyribonuclease BamHI; Deoxyribonucleases, Type II Site-Specific; DNA; DNA Cleavage; Fluorescence Resonance Energy Transfer; Guanosine; Kinetics; Oligonucleotides; Thymidine | 2014 |
Sulfonamide-bridged nucleic acid: synthesis, high RNA selective hybridization, and high nuclease resistance.
Topics: Bridged-Ring Compounds; Molecular Structure; Nucleic Acid Hybridization; Nucleic Acids; Oligonucleotides; Ribonucleases; RNA; Sulfonamides; Thymidine | 2014 |
Universal strategies for the DNA-encoding of libraries of small molecules using the chemical ligation of oligonucleotide tags.
Topics: Alkynes; Azides; Combinatorial Chemistry Techniques; Cycloaddition Reaction; Drug Discovery; Ficusin; Oligonucleotides; Small Molecule Libraries; Thymidine | 2014 |
Photochemical reactions of microcrystalline thymidine.
Topics: DNA; Molecular Structure; Oligonucleotides; Photochemistry; Thymidine; Thymine; Ultraviolet Rays | 2015 |
DNA-gadolinium-gold nanoparticles for in vivo T1 MR imaging of transplanted human neural stem cells.
Topics: Animals; Astrocytes; Cell Line; Cell Tracking; Cerebral Cortex; Contrast Media; Corpus Striatum; DNA; Gadolinium; Gold Colloid; Graft Survival; Humans; Magnetic Resonance Imaging; Nanoconjugates; Nanoparticles; Neural Stem Cells; Neurogenesis; Neurons; Oligonucleotides; Phantoms, Imaging; Signal-To-Noise Ratio; Thymidine | 2016 |
G-Quadruplexes with Tetra(ethylene glycol)-Modified Deoxythymidines are Resistant to Nucleases and Inhibit HIV-1 Reverse Transcriptase.
Topics: Antiviral Agents; Deoxyribonucleases; Drug Stability; Ethylene Glycol; G-Quadruplexes; HIV Reverse Transcriptase; Humans; Oligonucleotides; Reverse Transcription; Thymidine | 2016 |
Crystallization of and selenomethionine phasing strategy for a SETMAR-DNA complex.
Topics: Base Sequence; Binding Sites; Bromodeoxyuridine; Crystallization; Crystallography, X-Ray; DNA; DNA-Binding Proteins; Escherichia coli; Gene Expression; Humans; Inverted Repeat Sequences; Oligonucleotides; Plasmids; Protein Binding; Recombinant Fusion Proteins; Selenomethionine; Thymidine; Transposases; X-Ray Diffraction | 2016 |
The effect of l-thymidine, acyclic thymine and 8-bromoguanine on the stability of model G-quadruplex structures.
Topics: Deoxyadenosines; Electrophoresis, Polyacrylamide Gel; G-Quadruplexes; Guanine; Magnetic Resonance Spectroscopy; Models, Molecular; Oligonucleotides; Protein Binding; Structure-Activity Relationship; Thrombin; Thymidine | 2017 |
The free energy of locking a ring: Changing a deoxyribonucleoside to a locked nucleic acid.
Topics: Cytosine; Deoxyribonucleosides; DNA; Molecular Dynamics Simulation; Nucleic Acid Conformation; Oligonucleotides; Ribose; Thermodynamics; Thymidine | 2017 |
LNA Thymidine Monomer Enables Differentiation of the Four Single-Nucleotide Variants by Melting Temperature.
Topics: Alleles; DNA Probes; Molecular Dynamics Simulation; Oligonucleotides; Polymorphism, Single Nucleotide; Thymidine; Transition Temperature | 2017 |
A strongly pairing fifth base: oligonucleotides with a C-nucleoside replacing thymidine.
Topics: Base Pairing; Chromatography, High Pressure Liquid; DNA; Hydrogen Bonding; Models, Molecular; Molecular Structure; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligonucleotides; Organophosphorus Compounds; Structure-Activity Relationship; Thymidine; Transition Temperature | 2018 |
Photoactivatable oligonucleotide probes to trap single-stranded DNA binding proteins: Updating the potential of 4-thiothymidine from a comparative study.
Topics: Humans; Molecular Probes; Oligonucleotides; Replication Protein A; Thymidine | 2018 |
Synthesis of 2'-
Topics: Base Sequence; Chemistry Techniques, Synthetic; Oligonucleotides; Thymidine | 2019 |
Chemical synthesis and properties of modified oligonucleotides containing 5'-amino-5'-deoxy-5'-hydroxymethylthymidine residues.
Topics: Models, Molecular; Nucleic Acid Conformation; Oligonucleotides; Thymidine | 2020 |
Synthesis and properties of oligonucleotides bearing thymidine derivatives with 1,6-dioxaspiro[4.5]decane skeleton.
Topics: Molecular Structure; Oligonucleotides; Spiro Compounds; Thymidine | 2021 |
Synthesis of 4'-C-(aminoethyl)thymidine and 4'-C-[(N-methyl)aminoethyl]thymidine by a new synthetic route and evaluation of the properties of the DNAs containing the nucleoside analogs.
Topics: DNA; Escherichia coli; Nucleosides; Oligonucleotides; Oligonucleotides, Antisense; Ribonuclease H; RNA; Thymidine | 2022 |
4'-C-Aminoethoxy-Modified DNAs Exhibit Increased Nuclease Resistance, Sustained RNase H Activity, and Inhibition of KRAS Gene Expression.
Topics: DNA; Gene Expression; Humans; Oligonucleotides; Proto-Oncogene Proteins p21(ras); Ribonuclease H; RNA; Thymidine | 2022 |
Coumarin 6H-fused fluorescent probe for highly sensitive detection of coralyne using oligonucleotide-modified silver nanoparticles.
Topics: Adenine; Berberine Alkaloids; Coumarins; Fluorescent Dyes; Humans; Limit of Detection; Metal Nanoparticles; Oligonucleotides; Silver; Thymidine | 2022 |
Synthesis of 4'-C-(Aminoethyl)thymidine and 4'-C-[(N-Methyl)aminoethyl] Thymidine Nucleosides to Enhance DNA Stability.
Topics: Azides; DNA, Complementary; Nucleosides; Oligonucleotides; Oligonucleotides, Antisense; Thymidine | 2022 |
Synthesis, Duplex-Forming Ability, and Nuclease Resistance of Oligonucleotides Containing a Thymidine Derivative with a 1-Oxaspiro[4.5]decane Skeleton.
Topics: Alkanes; DNA; Nucleic Acids; Oligonucleotides; RNA; Skeleton; Spiro Compounds; Sugars; Thymidine | 2022 |
Caging of a Strongly Pairing Fluorescent Thymidine Analog with Soft Nucleophiles.
Topics: Base Pairing; Coloring Agents; Nucleosides; Nucleotides; Oligonucleotides; Thymidine | 2023 |