Page last updated: 2024-08-17

thymidine and mercaptopurine

thymidine has been researched along with mercaptopurine in 57 studies

Research

Studies (57)

TimeframeStudies, this research(%)All Research%
pre-199054 (94.74)18.7374
1990's3 (5.26)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Allison, AC; Hovi, T; Watts, RW; Webster, AD2
Raich, PC1
Bouchard, M; Bousser, J; Diaz-Mayo, C; Facquet-Danis, J; Percie-du-Sert, M; Zittoun, R1
Diesselhoff-Den Dulk, MM; Gassmann, AE; van Furth, R1
Gassmann, AE; van Furth, R1
Adamson, DJ; Carpenter, JW; Nelson, JA; Rose, LM1
Bakker, MA; Bökkerink, JP; Damen, FJ; De Abreu, RA; Hulscher, MW1
Krepelka, J; Melka, M; Miko, M1
Edelstein, M; Valeriote, F1
Abbatt, JD; Kaplan, JG; Quastel, MR1
O'Sullivan, WJ1
Richter, M; Singhal, SK1
Foley, GE; Lazarus, H1
Kummer, D1
Halterman, RH; Herberman, RB; Leventhal, BG; McCoy, JL; Rosenberg, EB1
Freireich, EJ; Hersh, EM; McCredie, KB1
Lea, MA; Morris, HP; Musella, A; Sasovetz, D1
Kröger, H; Papanastasiu, D1
Bell, JP; Gisler, RH1
Bull, FE; Ruddon, RW; Wheeler, RH1
Chary, KK; Humphrey, GB; Krivit, W; Nesbit, ME1
Gallo, RC; Levine, P; Smith, RG; Ting, RC; Whang-Peng, J1
Bakkeren, JA; de Vaan, GA; Schretlen, ED1
Ernst, P; Karle, H; Killmann, SA1
Aye, MT; McCulloch, EA; Niho, Y; Till, JE1
Borella, L; Green, AA1
Heitner, HI; Lippard, SJ; Sunshine, HR1
Muzik, H; Paterson, AR; Warnick, CT1
Cass, CE; Paterson, AR1
Dygin, VP; Fedortseva, RF; Goroshchenko, IuL; Mamaeva, SE1
Paterson, AR; Tidd, DM1
Benckhuijsen, C1
Velousova, AK1
van Furth, R1
Calman, N; Eng, B; Slater, LM; Wallerstein, H1
Craddock, CG; Lawrence, JS; Winkelstein, A1
Farrow, MG; Van Dyke, K1
Hersh, EM; LePage, GA1
Hartje, J; Wilmanns, W1
Cole, LJ; Miller, JJ2
Miller, JJ1
Baker, H; Frank, O; Hutner, SH1
Hurd, ER; Ziff, M1
Breitman, TR; Gallo, RC1
Kowollik, G; Langen, P1
Cook, JM; Franklin, TJ1
Balis, ME; Miller, DG; Salser, JS1
Al-Safi, SA; Maddocks, JL1
Kaji, H; Yander, G1
Browman, GP; Csullog, GW1
Shapkina, AV1
Inui, N; Sato, S; Takizawa, H1
Bökkerink, JP; De Abreu, RA; Lambooy, LH; Leegwater, PA; van den Heuvel, LP1
PERRY, S1
HODAS, S; YOUNG, CW1

Reviews

6 review(s) available for thymidine and mercaptopurine

ArticleYear
The role of de novo purine synthesis in lymphocyte transformation.
    Ciba Foundation symposium, 1977, Issue:48

    Topics: Adenine Phosphoribosyltransferase; Adenosine Deaminase; Adolescent; Adult; Allopurinol; Azaserine; B-Lymphocytes; Child; Child, Preschool; Humans; Hypoxanthine Phosphoribosyltransferase; Immunoglobulins; Lectins; Lesch-Nyhan Syndrome; Lymphocyte Activation; Male; Mercaptopurine; Mitogens; Phosphoribosyl Pyrophosphate; Purine-Nucleoside Phosphorylase; Purines; RNA; T-Lymphocytes; Thymidine; Uridine

1977
Cytosine arabinoside in experimental combination therapy.
    Seminars in oncology, 1985, Volume: 12, Issue:2 Suppl 3

    Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Cisplatin; Cyclophosphamide; Cytarabine; Daunorubicin; DNA; DNA Repair; Doxorubicin; Drug Interactions; Drug Resistance; Humans; Interphase; Leukemia; Mercaptopurine; Phosphorylation; Thioguanine; Thymidine; Time Factors

1985
Chemotherapy and the life cycle of leukaemic cells. A comparison between the growth characteristics of human acute leukaemia and the murine leukaemia L 1210.
    Folia medica Neerlandica, 1969, Dec-02, Volume: 12, Issue:2

    Topics: Anilides; Animals; Cell Division; Cyclophosphamide; Cytarabine; DNA, Neoplasm; Fluorouracil; Humans; Hydroxyurea; In Vitro Techniques; Leukemia; Leukemia L1210; Leukemia, Lymphoid; Mechlorethamine; Mercaptopurine; Methotrexate; Mice; Mitosis; Nitroso Compounds; Prednisone; Thymidine; Time Factors; Tritium; Vinblastine; Vincristine

1969
[Various aspects of the problem of selectivity in the chemotherapy of cancer].
    Voprosy onkologii, 1969, Volume: 15, Issue:8

    Topics: Animals; Antimetabolites; Antineoplastic Agents; Chemical Phenomena; Chemistry; DNA, Neoplasm; Fluorouracil; Mercaptopurine; Molecular Biology; Neoplasms, Experimental; Nucleotides; Pyridines; Pyrimidines; RNA, Neoplasm; Thymidine; Transferases

1969
Origin and kinetics of monocytes and macrophages.
    Seminars in hematology, 1970, Volume: 7, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Bone Marrow; Bone Marrow Cells; Cell Division; Culture Techniques; DNA; Encephalomyelitis, Autoimmune, Experimental; Glucocorticoids; Histocytochemistry; Hypersensitivity, Delayed; Inflammation; Leukocyte Count; Listeria monocytogenes; Listeriosis; Liver; Lung; Macrophages; Mercaptopurine; Mice; Monocytes; Neuroglia; Parabiosis; Peritoneum; Phagocytosis; Rabbits; Radiation Chimera; Synovial Membrane; Thymidine; Tritium

1970
BIOCHEMISTRY OF THE WHITE BLOOD CELL.
    JAMA, 1964, Dec-07, Volume: 190

    Topics: Acid Phosphatase; Alkaline Phosphatase; Biochemical Phenomena; Biochemistry; Carbohydrate Metabolism; DNA; Folic Acid Antagonists; Glutathione; Heparin; Histamine; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocytes; Lipid Metabolism; Lymphocytes; Mercaptopurine; Metabolism; Pathology; Peroxidases; Phagocytosis; Plasminogen; Pyrimidines; RNA; Thymidine; Trace Elements

1964

Other Studies

51 other study(ies) available for thymidine and mercaptopurine

ArticleYear
Immunological observations on patients with Lesch-Nyhan syndrome, and on the role of de-novo purine synthesis in lymphocyte transformation.
    Lancet (London, England), 1975, Dec-13, Volume: 2, Issue:7946

    Topics: Adenosine Deaminase; Adolescent; Azaserine; B-Lymphocytes; Child; Child, Preschool; Hemagglutinins; Humans; Hypersensitivity, Delayed; Hypoxanthine Phosphoribosyltransferase; Immunoglobulins; Immunologic Deficiency Syndromes; In Vitro Techniques; Lectins; Lesch-Nyhan Syndrome; Lymphocyte Activation; Lymphocytes; Male; Mercaptopurine; Mitogens; Purines; T-Lymphocytes; Thymidine

1975
Prediction of therapeutic response in acute leukaemia.
    Lancet (London, England), 1978, Jan-14, Volume: 1, Issue:8055

    Topics: Adult; Aged; Cells, Cultured; Cyclophosphamide; Cytarabine; Depression, Chemical; Drug Therapy, Combination; Female; Humans; In Vitro Techniques; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Prognosis; Remission, Spontaneous; Thymidine; Tritium; Vincristine

1978
[In vitro study of sensitivity of leukemic cells to cytotoxic drugs (anticytogram)].
    La Nouvelle presse medicale, 1975, Feb-08, Volume: 4, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Asparaginase; Carbon Radioisotopes; Cells, Cultured; Cyclophosphamide; Cytarabine; Daunorubicin; Depression, Chemical; Humans; In Vitro Techniques; Leukemia; Leukemia, Lymphoid; Mercaptopurine; Middle Aged; Monomethylhydrazine; Prednisolone; Remission, Spontaneous; Thymidine; Tritium; Uridine; Vincristine

1975
The effect of azathioprine (Imuran) on the cell cycle of promonocytes and the production of monocytes in the bone marrow.
    The Journal of experimental medicine, 1975, Mar-01, Volume: 141, Issue:3

    Topics: Acute Disease; Animals; Azathioprine; Bone Marrow; Bone Marrow Cells; Cell Count; Cell Division; Cell Nucleus; DNA; Inflammation; Kinetics; Male; Mercaptopurine; Mice; Mitosis; Monocytes; Spectrophotometry; Thymidine; Time Factors; Tritium

1975
The effect of azathioprine (Imuran) on the kinetics of monocytes and macrophages during the normal steady state and an acute inflammatory reaction.
    Blood, 1975, Volume: 46, Issue:1

    Topics: Animals; Autoradiography; Azathioprine; Cells, Cultured; Germ-Free Life; Inflammation; Kinetics; Leukocyte Count; Lymphocytes; Macrophages; Male; Mercaptopurine; Mice; Monocytes; Peritoneum; Thymidine; Tritium

1975
Mechanisms of action of 6-thioguanine, 6-mercaptopurine, and 8-azaguanine.
    Cancer research, 1975, Volume: 35, Issue:10

    Topics: Azaguanine; Azauridine; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Cytarabine; Deoxycytidine; DNA, Neoplasm; Guanine; Hypoxanthines; Imidazoles; Mercaptopurine; Methylthioinosine; Purines; RNA, Neoplasm; Thioguanine; Thymidine

1975
Biochemical evidence for synergistic combination treatment with methotrexate and 6-mercaptopurine in acute lymphoblastic leukemia.
    Haematology and blood transfusion, 1990, Volume: 33

    Topics: Antineoplastic Combined Chemotherapy Protocols; DNA, Neoplasm; Drug Synergism; Humans; Lymphocytes; Mercaptopurine; Methotrexate; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Purines; Thymidine; Tumor Cells, Cultured

1990
Inhibition of biosynthetic processes in P388 and Ehrlich ascites cells by cloturin.
    Drugs under experimental and clinical research, 1988, Volume: 14, Issue:9

    Topics: Adenine; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; DNA, Neoplasm; Kinetics; Leukemia P388; Mercaptopurine; Mice; Mustard Compounds; Neoplasm Proteins; Neoplasms, Experimental; RNA, Neoplasm; Thymidine; Tumor Cells, Cultured; Uridine

1988
Inhibition by ouabain of spontaneous D.N.A. synthesis in acute leukaemic leucocytes in vitro.
    Lancet (London, England), 1971, Apr-17, Volume: 1, Issue:7703

    Topics: Adult; Aged; Child; Child, Preschool; Cyclophosphamide; DNA; DNA, Neoplasm; Female; Humans; In Vitro Techniques; Lectins; Leukemia; Leukocytes; Lymphocyte Activation; Male; Mercaptopurine; Ouabain; Prednisone; Thymidine; Tritium

1971
Metabolic side-effects of allopurinol.
    Progress in biochemical pharmacology, 1974, Volume: 9

    Topics: Allopurinol; Antipyrine; Azathioprine; Azauridine; Benzothiadiazines; Dicumarol; Diuretics; Drug Synergism; Erythrocytes; Humans; Leukocytes; Mercaptopurine; Orotic Acid; Pentosyltransferases; Pyrimidines; Sodium Chloride Symporter Inhibitors; Thymidine; Xanthine Oxidase

1974
Cells involved in the immune response. IV. The response of normal and immune rabbit bone marrow and lymphoid tissue lymphocytes to antigens in vitro.
    The Journal of experimental medicine, 1968, Nov-01, Volume: 128, Issue:5

    Topics: Animals; Antigen-Antibody Reactions; Antigens; Appendix; Autoradiography; Bone Marrow; Bone Marrow Cells; Cats; Cattle; Culture Techniques; Dogs; Ear, Inner; Erythrocytes; Fluorescent Antibody Technique; gamma-Globulins; Hemagglutination Tests; Hemocyanins; Horses; Humans; Immune Tolerance; Immunization; Lymph Nodes; Lymphocytes; Lymphoid Tissue; Mercaptopurine; Ovalbumin; Rabbits; Salmonella; Serum Albumin; Serum Albumin, Bovine; Sheep; Spleen; Thymidine; Thymus Gland; Tritium

1968
The response in vitro, of continuous cultures of human lymphoblasts (CCRF-CEM cells) to chemotherapeutic agents.
    Biochemical pharmacology, 1967, Volume: 16, Issue:4

    Topics: Animals; Azaserine; Chloramphenicol; Culture Media; Culture Techniques; Cyclophosphamide; Cytarabine; Dactinomycin; Deoxyuridine; Floxuridine; Fluorouracil; Humans; Hydrocortisone; Lymphocytes; Mechlorethamine; Mercaptopurine; Methotrexate; Mitomycins; Puromycin; Thymidine; Triazines; Vincristine

1967
[Effects of cytostatics and x-rays on nucleic acid metabolism of solid, malignant tumors in vitro].
    Zeitschrift fur Krebsforschung, 1970, Volume: 74, Issue:1

    Topics: Adenine; Animals; Antineoplastic Agents; Carbon Isotopes; Dactinomycin; Depression, Chemical; DNA, Neoplasm; Estriol; Fluorouracil; Formates; Glycine; Hypoxanthines; In Vitro Techniques; Leucine; Mercaptopurine; Methotrexate; Methylprednisolone; Neoplasm Proteins; Neoplasms, Experimental; Nucleosides; Orotic Acid; Radiation Effects; RNA, Neoplasm; Testosterone; Thymidine; Triaziquone; Uracil; Uridine

1970
Cellular immune reactions to human leukemia.
    National Cancer Institute monograph, 1972, Volume: 35

    Topics: Antigens, Neoplasm; Bone Marrow; Bone Marrow Cells; Cell Membrane; Chromium Isotopes; Cytotoxicity Tests, Immunologic; Humans; Immunity, Cellular; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocyte Culture Test, Mixed; Mercaptopurine; Methotrexate; Prednisone; Skin Tests; Thymidine; Tritium; Vincristine

1972
Mechanism of production of inhibitor of lymphocyte blastogenic response to mitogens by cultured lymphoblastoid cell line cells.
    Transplantation, 1974, Volume: 17, Issue:2

    Topics: Cell Line; Contact Inhibition; Cycloheximide; Cytarabine; Dactinomycin; DNA; Humans; Lectins; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Lymphocytes; Mercaptopurine; Mitogens; Puromycin; Streptolysins; Thymidine; Tritium

1974
Effects of hydroxyurea and 6-mercaptopurine on growth and some aspects of carbohydrate metabolism in regenerating and neoplastic liver.
    Cancer research, 1970, Volume: 30, Issue:7

    Topics: Animals; Body Weight; Carcinoma, Hepatocellular; DNA; DNA, Neoplasm; Glucokinase; Glucose; Hepatectomy; Hexokinase; Hydroxyurea; Liver Glycogen; Liver Neoplasms; Liver Regeneration; Male; Mercaptopurine; Neoplasms, Experimental; Organ Size; Phosphofructokinase-1; Rats; Thymidine; Time Factors; Tritium

1970
[Influence of endoxan (cyclophosphamide) and 6-mercaptopurine on nucleic acid metabolism of rat spleen during synthesis of antibodies against Brucella abortus].
    Zeitschrift fur Naturforschung. Teil B, Chemie, Biochemie, Biophysik, Biologie und verwandte Gebiete, 1968, Volume: 23, Issue:1

    Topics: Animals; Antibody Formation; Brucella abortus; Cyclophosphamide; Depression, Chemical; DNA; Enzyme Induction; Hydrocortisone; In Vitro Techniques; Liver; Mercaptopurine; Nucleosides; Rats; RNA; Spleen; Thymidine; Tritium; Tyrosine Transaminase

1968
Studies on immunosuppression by purine nucleoside analogues. II. Effects on skin-graft rejection and immediate hypersensitivity in mice.
    Biochemical pharmacology, 1969, Volume: 18, Issue:9

    Topics: Anaphylaxis; Animals; Arthus Reaction; DNA; Female; Graft vs Host Reaction; Hypersensitivity, Immediate; Immunosuppressive Agents; Lymph Nodes; Lymphocytes; Mercaptopurine; Mice; Nucleosides; Oxidation-Reduction; Periodic Acid; Purines; Skin Transplantation; Spleen; Thymidine; Thymus Gland; Transplantation, Homologous; Tritium

1969
The effect of heparin on the cytotoxicity and uptake of anti-neoplastic drugs in cultured Burkitt lymphoma cells.
    Cancer research, 1974, Volume: 34, Issue:12

    Topics: Burkitt Lymphoma; Cell Division; Cell Survival; Cells, Cultured; DNA, Neoplasm; Fluorouracil; Heparin; Humans; Mechlorethamine; Mercaptopurine; Methotrexate; Thymidine; Time Factors; Tritium

1974
Impaired lymphocyte transformation in leukemic patients after intensive therapy.
    Cancer, 1972, Volume: 29, Issue:2

    Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Cobalt Isotopes; Cytarabine; Female; Humans; Leukemia, Lymphoid; Lymphocyte Activation; Male; Mechlorethamine; Mercaptopurine; Methotrexate; Mitogens; Prednisone; Radiation Effects; Remission, Spontaneous; Thymidine; Time Factors; Tritium; Vincristine

1972
Selective toxicity of rifamycin derivatives for leukaemic human leucocytes.
    Nature: New biology, 1972, Apr-12, Volume: 236, Issue:67

    Topics: Antibiotics, Antineoplastic; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cell Differentiation; Cells, Cultured; DNA Nucleotidyltransferases; DNA, Neoplasm; Humans; Hydroxyurea; Kinetics; Leukemia; Leukocytes; Lymphocytes; Mercaptopurine; Methotrexate; Rifampin; RNA, Neoplasm; Thymidine; Tritium; Uridine

1972
Phytohaemagglutinin stimulation of peripheral lymphocytes in children with acute lymphoblastic leukaemia during remission.
    Scandinavian journal of haematology, 1972, Volume: 9, Issue:1

    Topics: Adolescent; Cell Transformation, Neoplastic; Child; Child, Preschool; Cyclophosphamide; Humans; In Vitro Techniques; Lectins; Leukemia, Lymphoid; Leukocyte Count; Lymphocytes; Mercaptopurine; Methotrexate; Prednisone; Remission, Spontaneous; Stimulation, Chemical; Thymidine; Time Factors; Tritium; Vincristine

1972
Changing cytokinetic patterns of human leukaemic lymphoblasts during the course of the disease, studied in vivo.
    British journal of haematology, 1973, Volume: 24, Issue:2

    Topics: Adult; Bone Marrow Cells; DNA; Humans; Leukemia, Lymphoid; Leukocyte Count; Lymphocytes; Male; Mercaptopurine; Mitosis; Prednisone; Spectrophotometry; Thymidine; Time Factors; Tritium

1973
Studies of leukemic cell populations in culture.
    Blood, 1974, Volume: 44, Issue:2

    Topics: Autoradiography; Bone Marrow Cells; Cell Adhesion; Cell Division; Cell Separation; Cells, Cultured; Culture Media; Cytarabine; Daunorubicin; Freezing; Humans; Lectins; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Male; Mercaptopurine; Middle Aged; Prednisone; Radiation Effects; Thymidine; Tritium; Ultrafiltration

1974
Sequestration of PHA-responsive cells (T-lymphocytes) in the bone marrow of leukemic children undergoing long-term immunosuppressive therapy.
    Journal of immunology (Baltimore, Md. : 1950), 1972, Volume: 109, Issue:5

    Topics: Adolescent; Bone Marrow Cells; Cells, Cultured; Child; Child, Preschool; Cyclophosphamide; Female; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Lectins; Leukemia, Lymphoid; Male; Mercaptopurine; Methotrexate; Prednisone; Remission, Spontaneous; T-Lymphocytes; Thymidine; Tritium; Vincristine

1972
Metal binding by thionucleosides.
    Journal of the American Chemical Society, 1972, Dec-13, Volume: 94, Issue:25

    Topics: Base Sequence; Binding Sites; Guanosine; Mercaptopurine; Mercuribenzoates; Metals; Nucleic Acid Denaturation; RNA, Bacterial; Thiouracil; Thymidine

1972
Interference with nucleoside transport in mouse lymphoma cells proliferating in culture.
    Cancer research, 1972, Volume: 32, Issue:10

    Topics: Adenosine; Animals; Ascitic Fluid; Aza Compounds; Biological Transport; Bromodeoxyuridine; Carbon Isotopes; Cell Division; Cell-Free System; Cells, Cultured; Guanosine; Inosine; Lymphoma; Male; Mercaptopurine; Methotrexate; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Pyrazoles; Pyrimidinones; Pyrroles; Ribonucleosides; Thymidine; Time Factors; Transplantation, Homologous

1972
Mediated transport of nucleosides by human erythrocytes. Specificity toward purine nucleosides as permeants.
    Biochimica et biophysica acta, 1973, Feb-16, Volume: 291, Issue:3

    Topics: Arabinose; Biological Transport; Cell Membrane; Diffusion; Erythrocytes; Guanosine; Humans; In Vitro Techniques; Inosine; Mercaptopurine; Structure-Activity Relationship; Thymidine; Uridine

1973
[Cytogenetic analysis of the effect of 6-mercaptopurine on human chromosomes. II. Effect of 6-mercaptopurine on human lymphocytes in tissue culture].
    Tsitologiia, 1973, Volume: 15, Issue:11

    Topics: Autoradiography; Chromosome Aberrations; DNA; Humans; In Vitro Techniques; Lectins; Lymphocyte Activation; Lymphocytes; Mercaptopurine; Mitosis; Mutagens; Thymidine; Tritium

1973
Distinction between inhibition of purine nucleotide synthesis and the delayed cytotoxic reaction of 6-mercaptopurine.
    Cancer research, 1974, Volume: 34, Issue:4

    Topics: Animals; Cell Division; Cell Line; Cell Survival; Inosine; Leukemia, Experimental; Leukemia, Lymphoid; Mercaptopurine; Mice; Purine Nucleotides; Sulfides; Thioguanine; Thymidine

1974
Reversal of resistance to methotrexate in L1210 murine leukemia by uracil.
    Blood, 1971, Volume: 38, Issue:5

    Topics: Animals; DNA; Drug Resistance; Leukemia L1210; Mercaptopurine; Methotrexate; Nucleic Acids; Tetrahydrofolate Dehydrogenase; Thymidine; Tritium; Uracil

1971
Cell replication in the primary hemolysin response: the effect of six mercaptopurine.
    Journal of the Reticuloendothelial Society, 1971, Volume: 9, Issue:4

    Topics: Animals; Antibody Formation; Bone Marrow; Bone Marrow Cells; DNA; Hemolysin Proteins; Immunosuppression Therapy; Immunosuppressive Agents; Lymph Nodes; Lymphocytes; Male; Mercaptopurine; Monocytes; Mononuclear Phagocyte System; Rats; Spleen; Thymidine; Thymus Gland; Time Factors; Tritium

1971
A micro-system for screening anti-leukemic drugs utilizing human whole blood.
    Chemotherapy, 1971, Volume: 16, Issue:2

    Topics: Adult; Aged; Cytarabine; DNA; Evaluation Studies as Topic; Female; Humans; Infant; Leukemia; Leukocytes; Male; Mercaptopurine; Middle Aged; Quinacrine; RNA; Thymidine; Tritium; Uridine

1971
Effect of arabinosyl-6-mercaptopurine on the blastogenic responses in vitro of human lymphocytes to mitogenic agents.
    Biochemical pharmacology, 1971, Volume: 20, Issue:9

    Topics: Arabinose; Carbon Radioisotopes; Cells, Cultured; Dose-Response Relationship, Drug; Germ Layers; Humans; Lectins; Leucine; Lymphocytes; Mercaptopurine; Mitogens; Protein Biosynthesis; RNA; Sulfur Radioisotopes; Thymidine; Time Factors; Tritium; Uridine

1971
[Autoradiographic and enzyme-chemical studies of the DNA synthesis in leukemia cells. II. Thymidine-kinase and 3H-thymidine labelling index under cytostatic therapy].
    Klinische Wochenschrift, 1970, Jul-01, Volume: 48, Issue:13

    Topics: Adolescent; Adult; Autoradiography; Cell Differentiation; Cytarabine; DNA, Neoplasm; Female; Histocytochemistry; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisolone; Thymidine; Thymidine Kinase; Tritium

1970
Resistance of long-lived lymphocytes and plasma cells in rat lymph nodes to treatment with prednisone, cyclophosphamide, 6 mercaptopurine and actinomycin D. USNRDL-TR-67-24.
    Research and development technical report. United States. Naval Radiological Defense Laboratory, San Francisco, 1967, Jan-11

    Topics: Animals; Autoimmune Diseases; Cyclophosphamide; Dactinomycin; Immunoassay; Injections, Intraperitoneal; Lymphocytes; Mercaptopurine; Plasma Cells; Prednisone; Rats; Thymidine; Transplantation Immunology; Tritium

1967
Studies of the phylogeny and ontogeny of the specialized lymphatic tissue venules.
    Laboratory investigation; a journal of technical methods and pathology, 1969, Volume: 21, Issue:6

    Topics: Animals; Anura; Autoradiography; Biological Evolution; Bursa of Fabricius; Cell Movement; Chickens; Cyclophosphamide; Dactinomycin; Epithelium; Fishes; Humans; Lymph Nodes; Lymphocytes; Lymphoid Tissue; Mammals; Marsupialia; Mercaptopurine; Mice; Opossums; Rats; Reptiles; Spleen; Thoracic Duct; Thymidine; Tritium

1969
Antagonists of growth inhibition of Crithidia by allopurinol, a guanine analog.
    The Journal of protozoology, 1970, Volume: 17, Issue:2

    Topics: Allopurinol; Folic Acid; Hypoxanthines; Mercaptopurine; Pteridines; Thymidine; Trypanosoma

1970
Proliferation of mast cells after antigenic stimulation in adult rats.
    Nature, 1968, Jan-20, Volume: 217, Issue:5125

    Topics: Animals; Antigens; Antineoplastic Agents; Autoradiography; Cell Differentiation; Cyclophosphamide; Dactinomycin; Mast Cells; Mercaptopurine; Prednisone; Radiation Effects; Rats; Thymidine; Tritium; Typhoid-Paratyphoid Vaccines

1968
Studies on the anti-inflammatory action of 6-mercaptopurine.
    The Journal of experimental medicine, 1968, Oct-01, Volume: 128, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Autoradiography; Female; Leukocyte Count; Lymphocytes; Male; Mercaptopurine; Monocytes; Rabbits; Thymidine; Transplantation Immunology; Tritium

1968
The enzymatic mechanisms for deoxythymidine synthesis in human leukocytes. 3. Inhibition of deoxythymidine phosphorylase by purines.
    The Journal of biological chemistry, 1968, Oct-10, Volume: 243, Issue:19

    Topics: Allopurinol; Binding Sites; Carbon Isotopes; Cell-Free System; Deoxyuridine; Depression, Chemical; Drug Stability; Glucosyltransferases; Hot Temperature; Humans; Hypoxanthines; Kinetics; Leukocytes; Mercaptopurine; Nucleosides; Protein Denaturation; Thymidine; Thymine; Urea; Xanthines

1968
[5'-desoxy-5'-fluorothymidine, a new inhibitor of the DNA synthesis].
    Acta biologica et medica Germanica, 1968, Volume: 20, Issue:3

    Topics: Animals; Carcinoma, Ehrlich Tumor; Colorimetry; Depression, Chemical; DNA, Neoplasm; Fluorouracil; Mercaptopurine; Phosphates; Phosphorus Isotopes; RNA, Neoplasm; Spectrum Analysis; Thymidine; Triazines; Tritium; Uracil

1968
The inhibition of nucleic acid synthesis by mycophenolic acid.
    The Biochemical journal, 1969, Volume: 113, Issue:3

    Topics: Adenine; Animals; Antibiotics, Antineoplastic; Caproates; DNA, Neoplasm; Guanine; Guanine Nucleotides; Hypoxanthines; In Vitro Techniques; L Cells; Mercaptopurine; Mice; Neoplasms, Experimental; Oxidoreductases; Rats; Sarcoma, Yoshida; Thymidine

1969
Interaction of 6-mercaptopurine and antigens with cellular syntheses.
    Experimental and molecular pathology, 1967, Volume: 6, Issue:2

    Topics: Animals; Antibody Formation; Antigen-Antibody Reactions; Carbon; Carbon Isotopes; DNA; Erythrocytes; Formates; Hemagglutination; Histocytochemistry; Kidney; Liver; Male; Mercaptopurine; Mice; Phosphorus; Phosphorus Isotopes; Rabbits; RNA; Spleen; Thymidine; Tritium

1967
Effects of azathioprine on the human mixed lymphocyte reaction (MLR).
    British journal of clinical pharmacology, 1983, Volume: 15, Issue:2

    Topics: Azathioprine; Dithiothreitol; DNA; Erythrocytes; Glutathione; Humans; Lymphocyte Culture Test, Mixed; Mercaptopurine; Nitroimidazoles; Thymidine

1983
Investigating the myopathic effects of 6-mercaptopurine on developing skeletal muscle cells in vitro.
    Drug and chemical toxicology, 1984, Volume: 7, Issue:2

    Topics: Animals; Cell Survival; Chick Embryo; DNA; In Vitro Techniques; Leucine; Mercaptopurine; Microtubules; Muscle Proteins; Muscles; Muscular Diseases; Thymidine

1984
Modification of in vivo methotrexate antitumor effect in L1210 leukemia by induced impairment of purine salvage.
    Biochemical pharmacology, 1981, Apr-15, Volume: 30, Issue:8

    Topics: Animals; Cell Line; Cell Survival; Drug Resistance; Leukemia L1210; Male; Mercaptopurine; Methotrexate; Mice; Mutation; Purines; Thymidine

1981
[Changes in cells in the terminal portions of the pancreas following resection and administration of immunosuppressants].
    Arkhiv anatomii, gistologii i embriologii, 1981, Volume: 80, Issue:3

    Topics: Animals; Autoradiography; Azathioprine; DNA; Male; Mercaptopurine; Methionine; Microscopy, Electron; Mitotic Index; Pancreas; Pancreatectomy; Rats; Thymidine

1981
Mouse strain differences in induction of micronuclei by base analogues and nucleosides.
    Mutation research, 1993, Volume: 301, Issue:1

    Topics: Adenine; Animals; Bromodeoxyuridine; Bromouracil; Cytarabine; Erythrocytes; Female; Floxuridine; Guanosine; Mercaptopurine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Micronucleus Tests; Mitogens; Nucleosides; Purines; Pyrimidines; Species Specificity; Thymidine; Uridine

1993
Inhibition of DNA methylation in malignant MOLT F4 lymphoblasts by 6-mercaptopurine.
    Clinical chemistry, 1998, Volume: 44, Issue:3

    Topics: Carbon Radioisotopes; DNA Methylation; DNA, Neoplasm; Humans; Lymphocytes; Mercaptopurine; Methionine; Radioisotope Dilution Technique; Thymidine; Tritium; Tumor Cells, Cultured

1998
ACUTE EFFECTS OF CYTOTOXIC COMPOUNDS ON INCORPORATION OF PRECURSORS INTO DNA, RNA, AND PROTEIN OF HELA MONOLAYERS.
    Biochemical pharmacology, 1965, Volume: 14

    Topics: Anti-Bacterial Agents; Antimetabolites; Dactinomycin; DNA; Floxuridine; HeLa Cells; Humans; Leucine; Mercaptopurine; Metabolism; Methotrexate; Nucleosides; Pharmacology; Proteins; Puromycin; Research; RNA; Streptonigrin; Thymidine; Tissue Culture Techniques; Triethylenemelamine; Urethane; Uridine; Vinblastine

1965