Compounds > thymidine
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thymidine and irinotecan

thymidine has been researched along with irinotecan in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (50.00)18.2507
2000's4 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kono, A; Kuga, H; Sato, K; Shimazoe, T; Takeda, S1
Aonuma, M; Hirota, Y; Kawato, Y; Kuga, H; Sato, K1
Kono, A; Matsuoka, H; Saito, T; Seo, Y; Takiguchi, S; Tomoda, H; Yano, K1
Boorstein, RJ; Chiu, LN; Mahl, E; Mi, LJ1
Bigg, DC; Bronckart, Y; Chaboteaux, C; da Costa, PM; Decaestecker, C; Gordover, L; Harper, L; Kiss, R; Lavergne, O; Lesueur-Ginot, L; Malonne, H; Philippart, P1
Leu, YL; Prijovich, ZM; Roffler, SR1
Chen, W; Cloughesy, T; Czernin, J; Delaloye, S; Geist, C; Lai, A; Phelps, ME; Pope, W; Satyamurthy, N; Sayre, J; Silverman, DH1
Cox, A; Hansen, LT; Helleday, T; Meuth, M; Phear, G; Rodriguez, R; Scorah, J; Spang-Thomsen, M1

Other Studies

8 other study(ies) available for thymidine and irinotecan

ArticleYear
Camptothecin analog (CPT-11)-sensitive human pancreatic tumor cell line QGP-1N shows resistance to SN-38, an active metabolite of CPT-11.
    Biochemical and biophysical research communications, 1992, Oct-15, Volume: 188, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Biological Transport; Camptothecin; Cell Division; DNA Replication; DNA Topoisomerases, Type I; Drug Resistance; Humans; Irinotecan; Pancreatic Neoplasms; Thymidine; Tumor Cells, Cultured

1992
Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11.
    Cancer research, 1991, Aug-15, Volume: 51, Issue:16

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Survival; DNA Damage; DNA Replication; DNA, Single-Stranded; Irinotecan; Kinetics; Leukemia P388; Mice; RNA, Neoplasm; Thymidine; Topoisomerase I Inhibitors; Uridine

1991
Cytotoxicity of CPT-11 for gastrointestinal cancer cells cultured on fixed-contact-sensitive plates.
    Anti-cancer drugs, 1995, Volume: 6, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Survival; Colony-Forming Units Assay; Gastrointestinal Neoplasms; Humans; Irinotecan; Mice; Mice, Inbred BALB C; Survival Analysis; Thymidine; Tumor Cells, Cultured; Tumor Stem Cell Assay

1995
Toxicity of camptothecin to Chinese hamster cells containing 5-hydroxymethyl-2'-deoxyuridine in their DNA.
    Mutation research, 1995, Volume: 336, Issue:3

    Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Camptothecin; Cell Cycle; Cell Line; Cricetinae; Cricetulus; DNA Repair; Dose-Response Relationship, Drug; Drug Synergism; Irinotecan; Lung; Naphthoquinones; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; S Phase; Thymidine; Topoisomerase I Inhibitors

1995
Homocamptothecin, an E-ring-modified camptothecin, exerts more potent antiproliferative activity than other topoisomerase I inhibitors in human colon cancers obtained from surgery and maintained in vitro under histotypical culture conditions.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:4

    Topics: Antineoplastic Agents; Biopsy; Camptothecin; Cell Division; Colon; Colonic Neoplasms; Culture Techniques; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Inhibitors; Etoposide; Humans; Irinotecan; Thymidine; Topoisomerase I Inhibitors; Topotecan; Tritium; Tumor Cells, Cultured

2000
Effect of pH and human serum albumin on the cytotoxicity of a glucuronide prodrug of 9-aminocamptothecin.
    Cancer chemotherapy and pharmacology, 2007, Volume: 60, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; DNA Fragmentation; Dose-Response Relationship, Drug; Glucuronidase; Glucuronides; Humans; Hybridomas; Hydrogen-Ion Concentration; Hydrolysis; Immunoconjugates; Inhibitory Concentration 50; Irinotecan; Lactones; Molecular Structure; Prodrugs; Serum Albumin; Thymidine; Time Factors; Topotecan; Tritium

2007
Predicting treatment response of malignant gliomas to bevacizumab and irinotecan by imaging proliferation with [18F] fluorothymidine positron emission tomography: a pilot study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Oct-20, Volume: 25, Issue:30

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Camptothecin; Cell Proliferation; Female; Fluorine Radioisotopes; Glioma; Humans; Irinotecan; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Pilot Projects; Positron-Emission Tomography; Prognosis; Prospective Studies; Radiography; Radiopharmaceuticals; Survival Rate; Thymidine

2007
Thymidine selectively enhances growth suppressive effects of camptothecin/irinotecan in MSI+ cells and tumors containing a mutation of MRE11.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Sep-01, Volume: 14, Issue:17

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Colonic Neoplasms; DNA-Binding Proteins; Humans; Irinotecan; Mice; Mice, Nude; Microsatellite Instability; MRE11 Homologue Protein; Mutation; Thymidine; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays

2008