thymidine has been researched along with hydroxyurea in 501 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 442 (88.22) | 18.7374 |
| 1990's | 34 (6.79) | 18.2507 |
| 2000's | 19 (3.79) | 29.6817 |
| 2010's | 6 (1.20) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fliedner, TM; Haas, RJ; Harriss, EB; Hoelzer, D; Kurrle, E | 1 |
| Ross, DW | 1 |
| Grigg, GW; Sleigh, MJ | 1 |
| Mori, Y; Murota, SI; Otsuka, K | 1 |
| Lundgren, E; Roos, G | 1 |
| Heinonen, J; Lahti, R | 1 |
| Mathews, CK | 2 |
| Sobel, JS | 1 |
| Lotem, J; Sachs, L | 1 |
| Roti, LW; Stevens, AR | 1 |
| Johnson, RT; Schor, SL; Waldren, CA | 1 |
| Griffiths, TD; Tolmach, LJ | 1 |
| Forsdyke, DR; Scott, FW | 2 |
| Brunk, CF; Yaffe, D | 1 |
| Bui, TH; Funes-Cravioto, F; Hansson, K; Lambert, B; Lindsten, J | 1 |
| Bhuyan, BK; Day, KJ; Fraser, TJ | 1 |
| Burkhalter, M; Gautschi, JR; Ramseier, HP | 1 |
| Schempp, W; Sigwarth, I; Vogel, W | 1 |
| Enomoto, T; Tanuma, S; Yamada, M | 1 |
| Carlson, MD; Spooner, BS | 1 |
| Erbe, J; Plagemenn, PG; Richey, DP; Zylka, JM | 1 |
| Cordell, SL; Lawrence, HS; Young, JM | 1 |
| Reiter, RS; Solursh, M | 1 |
| Alford, BL; Barnes, EM | 1 |
| Marz, R; Plagemann, PG; Wohlhueter, RM | 1 |
| Bank, A; Gambari, R; Marks, PA; Rifkind, RA; Terada, M | 1 |
| De Carli, L; Giulotto, E; Mottura, A; Nuzzo, F | 1 |
| Adler, WH; Nariuchi, H | 1 |
| Kimler, BF; Leeper, DB | 1 |
| Leach, FR; Stadnicki, SS | 1 |
| Melzer, MS | 1 |
| Ikenaga, M; Kakunaga, T | 1 |
| Ashihara, T; Baserga, R | 1 |
| Maurer, RA | 1 |
| Aubertin, AM; Fellinger, E; Kirn, A; Travo, C | 1 |
| Doss, C; Gronowicz, ES; Schröder, J | 1 |
| Cox, RP; Fallon, RJ | 1 |
| Alison, MR; Wright, NA | 1 |
| Ford, SS; Shackney, SE | 1 |
| Allen, GP; Cohen, JC; O'Callaghan, DJ; Randall, CC | 1 |
| Bradley, MO; Sharkey, NA | 1 |
| Harriss, EB; Hoelzer, D | 1 |
| Banerjee, MR; Bodell, WJ | 1 |
| Brian, MJ; Stewart, BW | 1 |
| Hittelman, WN; Rao, PN | 1 |
| Miller, SA; Runner, MN | 2 |
| Igel, HJ; Kropko, ML; Lake, RS; Pezzutti, MR; Shoemaker, RH | 1 |
| Brooks, RF | 1 |
| Andoh, T; Kitagawa, T | 1 |
| Avila, J; Manso-Martínez, R | 1 |
| Chalkley, R; Nadeau, P; Oliver, DR | 1 |
| Dewar, D; Matthews, RH; Webb, TE | 1 |
| Epstein, SS; Iqbal, ZM; Majdan, M | 1 |
| Nachtwey, DS; Salamone, M; Worthington, DH | 1 |
| Sass, S; Sheppard, H; Tsien, WH | 1 |
| Bradley, MO; Ewig, RA; Kohn, KW; Sharkey, NA | 1 |
| Chandley, AC; Hotta, Y; Stern, H | 1 |
| Lambert, B; Ringborg, U | 1 |
| Benestad, HB | 2 |
| Kornacka, L; Malec, J; Sawecka, J | 1 |
| Hamlin, JL; Pardee, AB | 1 |
| Harris, G; Olsen, I | 1 |
| Bains, E; Jett, J; Maruyama, Y; Raju, MR | 1 |
| Ganeshaguru, K; Hoffbrand, AV; Hooton, JW; Tattersall, MH | 1 |
| Bondarev, GN; Terpilovskaia, ON; Tret'iak, TM; Vilenchik, MM | 1 |
| Szolgay, E; Tálas, M | 1 |
| Fournier, RE; Pardee, AB | 1 |
| Clarkson, B; Perez, A; Strife, A; Yataganas, X | 1 |
| Harris, G; Marriott, P; Olsen, I | 1 |
| Rozijn, TH; Sussenbach, JS; Vlak, JM | 1 |
| Dethlefsen, LA; Riley, RM; Sorensen, SP | 1 |
| Bohnert, E; Jung, EG | 1 |
| Alarif, A; Epstein, SS; Hasumi, K; Iqbal, ZM | 1 |
| Stevens, J; Stevens, YW | 1 |
| Altmann, H; Bernat, E; Klein, W; Kocsis, F; Tuschi, H | 1 |
| Grüneisen, A; Rajewsky, MF; Remmer, I; Uschkoreit, J | 1 |
| Cleaver, JE; Painter, RB | 1 |
| Hewitt, RR; Humphrey, RM; Meyn, RE | 2 |
| Böhme, R; Fouquet, H; Sauer, HW; Scheller, K; Wick, R | 1 |
| Lee, MJ; Roth, SI | 1 |
| Dethlefsen, LA; Roti Roti, JL | 2 |
| Tausch, G | 1 |
| Frankfurt, OS | 2 |
| Kohn, A | 1 |
| Hildebrand, CE; Tobey, RA; Walters, RA | 1 |
| Baril, EF; Davis, PB; Laszlo, J | 1 |
| Epstein, SS; Hasumi, K; Iqbal, Z | 1 |
| DeLapp, NW; Karasek, MA | 1 |
| Frindel, E; Rockwell, S; Tubiana, M | 1 |
| Sasvári-Székely, M; Spasokukotskaja, T; Staub, M; Taljanidisz, J | 1 |
| Brochard, P; Jaurand, MC; Levy, F; Pilliere, F; Renier, A | 1 |
| Falknäs, AK; Fryklund, J; Helander, HF | 1 |
| Daikoku, T; Maeno, K; Nishiyama, Y; Yamamoto, N | 1 |
| Guthrie, J; Logsdon, CD; Williams, JA | 1 |
| Finney, KJ; Harris, AL; Ince, P; Moorghen, M; Watson, AJ | 1 |
| Kovacs, E; Langemann, H | 1 |
| Aoki, A; Furukawa, T; Koike, T; Moriyama, Y; Nikkuni, K; Nomoto, N; Shibata, A; Shinada, S; Takahashi, M | 1 |
| Bhalla, K; Grant, S; Swerdlow, P | 1 |
| Howl, J; Ismail, T; McMaster, P; Neuberger, JM; Strain, AJ; Wheatley, M | 1 |
| Cao, G; Cleary, SF; Liu, LM | 1 |
| Howell, ML; Mathews, CK; Slabaugh, MB; Wang, Y | 1 |
| Bunce, GE; Hess, JL; Huang, LL | 1 |
| Labanowska, J; Tolmach, LJ | 1 |
| DeSesso, JM; Goeringer, GC | 1 |
| Holmes, KT; Hunt, NH; King, NJ; Lean, CL | 1 |
| Chen, SY; Thompson, HA; Vodkin, M; Williams, JC | 1 |
| Brody, JS; Clement, A; Riedel, N | 1 |
| Hanaoka, F; Yamada, K; Yamada, M | 1 |
| Hanotte, O; Menozzi, FD; Miller, AO | 1 |
| Bjursell, G; Sjöberg, RM; Sunnerhagen, P | 1 |
| Cortés, F; Mateos, S; Ortiz, T; Piñero, J | 1 |
| Rabes, HM; Röttgen, V | 1 |
| Fujikawa-Yamamoto, K; Odashima, S | 1 |
| Spath, A; Tempel, K | 1 |
| Cleaver, JE | 2 |
| Darling, AJ; McDougall, IM; Preston, VG | 1 |
| Frindel, E; Necas, E; Znojil, V | 1 |
| Cheng, YC; Grill, SP; Nutter, LM | 1 |
| Lorenzo, JA; Quinton, J; Raisz, LG; Sousa, S | 1 |
| Brunelli, MA; Chiricolo, M; Franceschi, C; Marini, M; Zunica, G | 1 |
| Castellino, FJ; Sator de Serrano, V; Scott, FM | 1 |
| Li, XZ; Yan, ZA; Zhou, XT | 1 |
| Russev, G; Vassilev, L | 1 |
| Bassukas, ID; Maurer-Schultze, B; Siebert, M | 1 |
| Leffak, M | 1 |
| Chitnis, MP; Satyamoorthy, K | 1 |
| Audus, KL; Holthaus, SR; Shinogle, JA; van Bree, JM | 1 |
| Hayashi, M; Honma, Y; Hozumi, M; Okabe-Kado, J | 1 |
| Coutinho, AA; Freitas, AA; Rocha, B | 1 |
| Adolph, KW | 1 |
| Grunow, R; Jahn, S; Kiessig, ST; Schäfer, H; Volk, HD; von Baehr, R | 1 |
| Rush, JS; Snow, EC; Waechter, CJ | 1 |
| Coetzee, ML; Francavilla, A; Ove, P; Scalamogna, P; Starzl, TE | 1 |
| Almendral, A; Kovacs, E | 1 |
| Mironov, NM | 1 |
| Hochmann, J | 1 |
| Cristofalo, VJ; Gorman, SD | 1 |
| Kovacs, E; Müller, H; Stucki, D; Weber, W | 1 |
| Golos, B; Malec, J; Sawecka, J | 1 |
| Haanen, C; Marie, JP; Marquet, J; Zittoun, J; Zittoun, R | 1 |
| Ashman, CR; Davidson, RL; Kaufman, ER | 1 |
| Melamede, RJ; Wallace, SS | 1 |
| Bacon, PE; Brown, NC; Carter, GL; Cory, JG; Montgomery, JA; Sato, A | 1 |
| Nicander, B; Reichard, P | 3 |
| Licastro, F; Sarafian, T; Verity, AM; Walford, RL | 1 |
| Lipman, JM; Sokoloff, L | 1 |
| Krieger, NS; Stathopoulos, VM; Stern, PH | 1 |
| Dubrava, TG; Gol'tsev, AN; Tsutsaeva, AA | 1 |
| Clark, RW; Stickel, SK | 1 |
| Chalkley, R; Louters, L | 1 |
| Nemirovskiĭ, LE; Vasil'ev, VK | 1 |
| Catena, C; Cordelli, E; Uccelli, R | 1 |
| Malick, NC; Snyder, RD | 1 |
| Ishiguro, T; Ochi, T; Ohsawa, M | 1 |
| Lewensohn, R; Ringborg, U | 1 |
| Braly, P; Simpson, L | 1 |
| Seidel, HJ | 1 |
| Tobey, RA | 1 |
| Crissman, HA; Tobey, RA | 2 |
| DiPaolo, JA; Popescu, NC | 1 |
| Briganti, G; Elli, R; Falpo, B; Mauro, F; Zupi, G | 1 |
| Clarkson, BD; Yataganas, X | 1 |
| Frank, W; Manso-Martinez, R | 1 |
| Fievez, M; Malpoix, P; Zampetti-Bosseler, F | 1 |
| Gelbard, AS; Kim, JH; Perez, AG | 1 |
| Steinert, M; Van Assel, S | 2 |
| Ammermann, D; Sapra, GR | 1 |
| Baugnet-Mahieu, L; Goutier, R; Shima, A | 1 |
| Andersson, J; Melchers, F | 2 |
| Pennington, TH | 1 |
| Cohen, LS; Studzinski, GP | 1 |
| Djordjevic, B; Kim, JH | 1 |
| Domon, M; Rauth, AM | 1 |
| Coleman, AW; Coleman, JR; Kankel, D; Werner, I | 1 |
| Coyle, M; McMahon, M; Strauss, B | 1 |
| Bell, E | 1 |
| Weiss, BG | 1 |
| Fox, M; Nias, AH | 1 |
| Morgan, C; Rosenkranz, HS; Zweig, M | 1 |
| Fabricius, E; Hülser, DF; Rajewsky, MF | 2 |
| Coyle, M; Dolyniuk, M; Kato, K; McMahon, M; Strauss, B | 1 |
| Amaldi, F; Carnevali, F; Leoni, L; Mariotti, D | 1 |
| Jailkhani, BL; Talwar, GP | 1 |
| Hand, R; Tamm, I | 2 |
| Ritter, EJ; Scott, WJ; Wilson, JG | 2 |
| Bajaj, SK; Dass, CM; Rao, KV | 1 |
| Kafatos, FC; Selman, K | 1 |
| Goldstein, DA; Hall, MR; Lerner, RA; Meinke, W | 1 |
| Mattoccia, LP; Roberti, S | 1 |
| Krakoff, IH; Nordenskjöld, A | 1 |
| Rossman, TG; Vilcek, J | 1 |
| Bitter-Suermann, D; Clauss, I; Falke, D | 1 |
| Lea, MA; Morris, HP; Musella, A; Sasovetz, D | 1 |
| Krauss, G; Probst, H; Ullrich, A | 1 |
| Baden, HP; Delhanty, JD; Parrington, JM | 1 |
| Kapp, LN; Okada, S | 1 |
| Rideau, C; Smulson, ME | 1 |
| Burroughs, MA; Derge, JG; Hampar, B; Martos, LM; Tagamets, MA | 1 |
| Bernheim, NJ; Brandt, WN; Flamm, WG | 1 |
| Magnusson, G | 2 |
| Laipis, PJ; Levine, AJ | 1 |
| Sokol, F; Tan, KB | 2 |
| Defendi, V; Seemayer, NH | 1 |
| Smith, BJ; Wigglesworth, NM | 1 |
| Kirk-Bell, S; Lehmann, AR; Shall, S; Whish, WJ | 1 |
| Choe, BK; Rose, NR | 1 |
| Erbe, J; Plagemann, PG; Richey, DP; Zylka, JM | 1 |
| Scudiero, D; Strauss, B | 1 |
| Derge, JG; Hampar, B; Showalter, SD | 1 |
| Erbe, J; Plagemann, PG | 1 |
| Tsuruhara, A; Tsuruhara, T | 1 |
| Girard, M; Manteuil, S | 1 |
| Balhorn, R; Chalkley, R; Granner, D; Tanphaichitr, N | 1 |
| Chang, SY; Derge, JG; Hampar, B; Nonoyama, M; Showalter, SD; Tagamets, A | 1 |
| Glaser, R; Mele, J; Nonoyama, M; Rapp, F; Zimmerman, J | 1 |
| Hansen, HH; Krezoski, SK; Muggia, FM | 1 |
| Becker, Y; Ben-Zeev, A; Weinberg, E | 1 |
| Lin, SS; Munyon, W | 1 |
| Banerjee, S; Bhattacharya, A; Datta, A | 1 |
| Basilico, C; Burstin, SJ; Meiss, HK | 1 |
| Meneghini, R | 1 |
| Bhattacharya, A; Datta, A; Puri, M | 1 |
| Clarkson, SG | 1 |
| Granner, DK; Thompson, EB; Tomkins, GM | 1 |
| Byron, JW | 2 |
| Injeyan, HS; McLaughlin, J; Meerovitch, E | 1 |
| Fil, W; Flores, L; Holowczak, JA; Thomas, V | 1 |
| Baserga, R; Nicolini, C | 1 |
| Alberts, DS; Golde, DW | 1 |
| Fisher, RJ; Jabara, AG; Wilson, FC | 1 |
| Hawtrey, AO; Robertson, G; Scott-Burden, T | 1 |
| Lewis, WH; Wright, JA | 1 |
| Bock, E; Bock, O; Heit, W; Kubanek, B; Schreml, W | 1 |
| Haars, EG; Schmidt, JM | 1 |
| Hotta, Y; Stern, H | 2 |
| Ferguson, TF; Prottey, C | 1 |
| Wilt, FH; Wu, RS | 1 |
| Bello, LJ | 1 |
| Berger, H | 1 |
| Bacalao, J; Rieber, M | 1 |
| Bjursell, G; Skoog, L | 1 |
| Trosko, JE; Yager, JD | 1 |
| Buhl, SN; Regan, JD; Setlow, RB | 1 |
| Gurley, LR; Tobey, RA; Walters, RA | 1 |
| Altmann, H; Eberl, R; Klein, G; Wottawa, A | 1 |
| Gallo, RC; Levine, P; Smith, RG; Ting, RC; Whang-Peng, J | 1 |
| Brachet, J; Huez, G; Zampetti-Bosseler, F | 1 |
| Pardee, AB | 1 |
| Odmark, G | 1 |
| Krishnan, D; Painter, RB | 1 |
| Cunningham, DD; Remo, RA | 1 |
| Breindl, M; Gallwitz, D | 1 |
| Naot, Y; Shalitin, C | 1 |
| Bruner, R; Elliott, J; Souther, A | 1 |
| Sinha, NK; Snustad, DP | 1 |
| Little, JW | 1 |
| Goscin, LA; Hall, DH | 1 |
| Fangman, WL; Hill, WE | 1 |
| Bowles, MG; Karam, JD | 1 |
| Bases, R; Erlanger, B; Hsu, KC; Liebeskind, D | 1 |
| Brachet, J; De Schutter, A; Hanocq, F; Hubert, E | 1 |
| Cameron, IL; Rudick, MJ | 1 |
| Cleaver, JE; Lett, JT; Thomas, GH; Trosko, JE | 1 |
| Banerjee, S; Kelleher, JK; Margulis, L; Winston, M; Younger, KB | 1 |
| Gasc, JM; Liébart, JC | 1 |
| Cameron, IL; Jeter, JR | 1 |
| Barnea, A; Lindner, HR | 1 |
| Gaudin, D; Gregg, RS; Yielding, KL | 1 |
| Jacobs, AJ; O'Brien, RL; Paolilli, P; Parker, JW | 1 |
| Cikes, M; Friberg, S; Klein, G | 1 |
| Bosmann, HB | 1 |
| Heidelberger, C; Palzer, RJ | 1 |
| Howard, D; Miller, M; Morley, A; Quesenberry, PJ; Rickard, K; Stohlman, F | 1 |
| Abbott, J; Holtzer, H; Mayne, R | 1 |
| Fache, I; Haas, RJ | 1 |
| Homan, ER; Neil, GL | 1 |
| Frindel, E; Tubiana, M; Vassort, F; Winterholer, M | 1 |
| Sussenbach, JS; van der Vliet, PC | 1 |
| Concannon, JP; Hagemann, RF | 1 |
| Hershey, H; Mueller, GC; Stieber, J | 1 |
| Harris, JW; Teng, SS | 1 |
| Comings, DE; Okada, TA | 1 |
| Kinzel, V; Kreibich, G; Schmid, E; Süss, R | 1 |
| Lepekhin, AF; Malinovskiĭ, OV; Peshin, NN; Sheĭkina, TA | 1 |
| Potten, CS | 1 |
| Gibson, JE; Short, RD | 1 |
| Lee, TC; Maruyama, Y; Sullivan, S | 1 |
| Borchert, R; McChesney, JD | 1 |
| Balhorn, R; Chalkley, R; Granner, DK; Tanphaichitr, N | 1 |
| Weryha, A | 1 |
| Lederrey, C; Maurice, PA | 1 |
| Graw, CM; Graw, RG; Lohrmann, HP | 1 |
| Lothrop, D; Nicholson, BL | 1 |
| Birkett, S; Salaman, DF | 1 |
| Bourne, RA; Bryant, JA; Falconer, IR | 1 |
| Carr, HS; Pollak, RD; Rosenkranz, S | 1 |
| Deering, RA; Kantor, GJ | 1 |
| Evans, RG; Norman, A | 1 |
| Carr, HS; Jacobs, SJ; Rosenkranz, HS | 1 |
| Pollak, RD; Rosenkranz, HS; Schmidt, RM | 1 |
| Hobbs, MD; Warner, HR | 1 |
| Benckhuijsen, C | 1 |
| Rosenkranz, HS | 1 |
| Jorgensen, SE; Koerner, JF; Snustad, P; Warner, HR | 1 |
| Alves, MA; Laicine, EM; Sauaia, H | 1 |
| Dales, S; Ichihashi, Y; Matsumoto, S | 1 |
| Capizzi, RL; Creasey, WA; DeConti, RC | 1 |
| Carr, HS; Ellner, CJ; Mednis, A; Rosenkranz, HS; Winshell, EB | 1 |
| Pasternak, J; Samoiloff, MR | 1 |
| Bassleer, R; Gauthier, MP | 1 |
| Lo, TM; McCann, JJ; Webster, DA | 1 |
| Kingdon, HS; Morley, CG | 1 |
| O'Neill, MC; Stockdale, FE | 1 |
| Kember, NF | 1 |
| Gelfant, S; Singer, RM | 1 |
| Lehmann, AR | 1 |
| Hamilton, S; Webster, G | 1 |
| Grunicke, H; Puschendorf, B | 1 |
| Dawson, KM | 1 |
| Kraemer, KH; Robbins, JH | 1 |
| Djaidetti, M; Marks, PA; Preisler, H; Rifkind, RA | 1 |
| Fukuhara, M; Horikawa, M; Nikaido, O; Sugahara, T; Suzuki, F | 1 |
| Bennett, LR; Byfield, JE; Lee, YC | 1 |
| Bosmann, HB; Kessel, D; Lohr, K | 1 |
| Chu, EH; Smith, DB | 1 |
| Johanson, KJ | 1 |
| Stoughton, RB | 1 |
| Connell, DI; DiPaolo, JA; Riechers, LA | 1 |
| Matsuzawa, D; Morita, H; Nakayama, T | 1 |
| Haas, RJ | 1 |
| Carnes, JE; Gale, GR | 1 |
| Barry, JM; Green, CD; Skarda, J | 1 |
| Farber, E; Lieberman, MW; Rutman, JZ | 1 |
| Dethlefsen, LA | 1 |
| Fujiwara, Y; Tanaka, S; Terasima, T; Yasukawa, M | 1 |
| Adams, RL; Berryman, S; Thomson, A | 1 |
| Sinclair, WK | 4 |
| Dukes, PP | 1 |
| Smets, LA | 2 |
| Arlett, CF | 1 |
| Ayad, SR; Fox, BW; Fox, M | 1 |
| Gale, GR | 3 |
| Gallwitz, D; Mueller, GC | 1 |
| Djordjevic, B; Evans, RG; Perez, AG; Weill, MK | 1 |
| Graffi, A; Tschiersch, B | 1 |
| Barry, JM; Mayne, R | 1 |
| Rajewsky, MF | 1 |
| Kuroki, T; Sato, H | 1 |
| Janicki, RH | 1 |
| Gillette, EL; Tannock, IF; Withers, HR | 1 |
| Janicki, R; Lingis, J | 1 |
| Coyle, MB; Strauss, B | 1 |
| Brockman, RW; Laster, WR; Schabel, FM; Shaddix, S | 1 |
| Chae, CB; Irvin, JL; Krasny, H; Piantadosi, C; Williams, A | 1 |
| Farber, E; Landay, M; Lee, TN; Liang, H; Lieberman, MW; Starr, R; Verbin, RS | 1 |
| Yatani, R | 1 |
| Norman, A; Spiegler, P | 1 |
| Goerttler, K; Hinderer, H; Kaufmann, K; Volm, M | 1 |
| Bohne, F; Fache, I; Fliedner, TM; Haas, RJ | 1 |
| Devik, F; Hennings, H | 1 |
| Djordjevic, B; Gelbard, AS; Kim, JH; Perez, AG | 1 |
| Baes, C; Baugnet-Mahieu, L; Goutier, R | 1 |
| Hennings, H | 1 |
| McGuire, WL; O'Malley, BW | 1 |
| Bell, WC; Maassab, HF | 1 |
| Maurer, HR; Süss, R | 1 |
| Granoff, A; Kucera, LS | 1 |
| Eker, P | 1 |
| Cooper, EH; Kierski, J; Topping, NE | 1 |
| Philips, FS; Schwartz, HS; Sternberg, SS | 1 |
| Gale, GR; Hynes, JB; Smith, AB | 1 |
| Boutwell, RK; Potter, VR; Smith, HC | 1 |
| Carrier, WL; Regan, JD; Trosko, JE | 1 |
| Fanestil, DD | 1 |
| Sung, SC | 1 |
| Baserga, R; Farber, E | 1 |
| Heilporn-Pohl, V; Limbosch-Rolin, S | 1 |
| Friedman, DL; Mueller, GC | 1 |
| Adams, RL; Burdon, RH | 1 |
| Morse, BS; Rencricca, NJ; Stohlman, F | 1 |
| Penman, S; Vesco, C | 1 |
| Gothoskar, BP; Ranadive, KJ; Rbose, S | 1 |
| Pfeiffer, SE; Tolmach, LJ | 1 |
| Cronin, AP; Philips, FS; Schwartz, HS; Sodergren, JE; Sternberg, SS; Vidal, PM | 1 |
| Karnofsky, DA; Schochetman, G; Young, CW | 1 |
| Balis, ME; Hodas, S; Schochetman, G; Young, CW | 1 |
| Adams, RL; Lindsay, JG | 1 |
| Djordjevic, B; Tolmach, LJ | 1 |
| Byfield, JE; Scherbaum, OH | 1 |
| Hunter, GD; Kimberlin, RH | 1 |
| Detke, S | 1 |
| Bentley, P; Bieri, F; Stäubli, W; Waechter, F | 1 |
| Burry, RW | 1 |
| Liu, FC | 1 |
| Fox, RM; Kefford, RF; Taylor, IW; Tripp, EH | 1 |
| Brunengraber, H; Busby, WF; Goldman, ME; Imamura, T; Wogan, GN | 1 |
| Collins, AR; Downes, CS; Johnson, RT | 1 |
| Banerjee, PT; LaGree, K; Mui, SC; Strauss, PR | 1 |
| Janakidevi, K; Kroms, M; Lee, KT; Murray, CD; Thomas, WA | 1 |
| Hanaoka, F; Kato, H; Yamada, K; Yamada, M | 1 |
| Costanzo, C; Kubota, K; Preisler, HD | 1 |
| Hoshino, T; Kobayashi, S | 1 |
| Lea, MA; Randolph, V; Sumas, ME | 1 |
| Den Hollander, JE; Erasmus, DA | 1 |
| Howell, SB; Pfeifle, CE; Streifel, JA | 1 |
| Boehm, TL; Drahovsky, D; Kreis, W | 1 |
| Ayurawa, D; Iwata, K; Seno, T | 1 |
| Charles, WC; Cleaver, JE | 1 |
| Halprin, KM; Levine, V; Taylor, JR; Woodyard, C | 1 |
| Bianchi, V; Levis, AG; Zantedeschi, A | 1 |
| Clarkson, B; Lambek, C; Yen, A | 1 |
| Howell, SB; Streifel, JA | 1 |
| Chen, MG; Gallicchio, VS | 1 |
| Hauser, F; Necas, E | 1 |
| Hume, WJ; Potten, CS | 1 |
| Johnson, LF; Muench, AJ; Rao, LG | 1 |
| Abe, I; Hori, K; Saito, S; Sato, H; Suzuki, M | 1 |
| Adolph, KW; Phelps, JP | 1 |
| Chang, KS; Shires, TK | 1 |
| Necas, E; Neuwirt, J; Ponka, P | 1 |
| Agrelo, CE; Severn, BJ | 1 |
| Carpenter, JG; Dahle, DB; Griffiths, TD; Meechan, PJ | 1 |
| Romanov, IuA; Rybakov, VP; Timofeev, AV | 1 |
| Barra, R; Collin, GR; Lea, MA; Parsons, J | 1 |
| Brun, R | 1 |
| DiPaolo, JA; Epstein, SM; Mironescu, SG | 1 |
| Fialkoff, H; Goodman, MF; Seraydarian, MW; Yang, JJ | 1 |
| Blackburn, MJ; Patt, HM | 1 |
| Gans, JH; Smuckler, EA | 1 |
| Quesenberry, PJ; Stanley, K | 1 |
| Biskobing, DM; Fan, X; Rubin, J | 1 |
| Forýtková, L; Hrazdira, I; Mornstein, V | 1 |
| Foresti, M; Gaudio, L; Geraci, G; Paoletti, I | 1 |
| Gupta, SK; Singh, JP | 1 |
| Auclair, C; Carteau, S; Goulaouic, H; Mouscadet, JF; Subra, F | 1 |
| Alcain, FJ; Crane, FL; Löw, H | 1 |
| Bali, JP; Duperray, C; Rémy-Heintz, N | 1 |
| Li, Y; Pitot, HC; Sattler, GL | 1 |
| Akatsu, T; Kurokawa, T; Stanley, ER; Suda, T; Takahashi, N; Tamura, T; Tanaka, S; Udagawa, N | 1 |
| Frels, JS; Jahn, CL | 1 |
| Lawrence, TS; McGinn, CJ; Shewach, DS | 1 |
| Hamlin, JL; Kalejta, RF | 1 |
| Julias, JG; Pathak, VK | 1 |
| Chen, J; Donovan, S; Hong, FD; Nisen, PD; Schneider, N | 1 |
| Merigan, TC; Palmer, S; Shafer, RW | 1 |
| Matsui, T; Taketo, A | 1 |
| Matsuhisa, T | 1 |
| Goehle, S; Lamb, JR; Ludlow, C; Simon, JA | 1 |
| Bontemps, F; Cardoen, S; Delacauw, A; Ferrant, A; Husson, B; Rosier, JF; Van den Berghe, G; Van Den Neste, E | 1 |
| Arnaudeau, C; Erixon, K; Helleday, T; Jenssen, D; Lundin, C; Meuth, M; Schultz, N | 1 |
| Fagny, C; Robberecht, P; Svoboda, M; Vandevelde, M | 1 |
| Gajary, LC; Mansky, LM; Pearl, DK | 1 |
| Chen, L; Jacob, TJ; Kangrong, C; Nie, S; Ping, Z; Rawle, M; Wang, L; Zhang, J; Zhu, L | 1 |
| Higgin, JJ; Makarov, AA; Mitkevich, VA; Raines, RT; Yakovlev, GI | 1 |
| Arnaudeau, C; Hansen, LT; Helleday, T; Lundin, C; Mohindra, A; Schultz, N | 1 |
| Kimura, H; Obuse, C; Ohta, S; Tatsumi, Y; Tsurimoto, T | 1 |
| Chow, JP; Ho, CC; Ho, HT; Ma, KH; Poon, RY; Siu, WY | 1 |
| MOHLER, WC | 1 |
| HODAS, S; YOUNG, CW | 1 |
| FRENKEL, EP; SKINNER, WN; SMILEY, JD | 1 |
| LEVY, JA; ROSENKRANZ, HS | 1 |
| Barreiro, P; Camino, N; de Mendoza, C; Núñez, M; Paxinos, E; Soriano, V | 1 |
| Ahn, JM; Kim, JH; Lee, HC; Lee, SN | 1 |
| Ferrara, L; Kmiec, EB; Parekh-Olmedo, H | 1 |
| Lim, CS; Liu, N | 1 |
| Hayashizaki, Y; Nishida, H; Ookawa, H; Suzuki, T; Tomaru, Y | 1 |
| Darzynkiewicz, Z; Huang, X; Kurose, A; Tanaka, T; Traganos, F | 1 |
| Fernando, R; Foster, JS; Henley, D; Isbill, M; Wimalasena, J | 1 |
| Nishikawa, T; Ohnishi, Y; Sato, T; Tanaka, K | 1 |
| Brocardo, MG; Henderson, BR; Johnson, M; Sharma, M | 1 |
| Gong, Y; Guo, H; Jiang, H; Liu, Q; Liu, Z; Shao, C; Sun, Z; Tischfield, JA; Xu, B; Zou, Y | 1 |
| Liberal, J; Liberal, V; Martinsson-Ahlzén, HS; McGowan, CH; Reed, SI; Spruck, CH; Widschwendter, M | 1 |
| Barrera, P; Lozano, E; Nieto, M; Sartor, T; Sosa, MA; Tonn, C | 1 |
| Henderson, BR; Johnson, MA; Mok, MT; Sharma, M | 1 |
| Jin, Y; Li, M; Qi, S; Yao, W; Zhang, S; Zhao, J | 1 |
6 review(s) available for thymidine and hydroxyurea
| Article | Year |
|---|---|
Critique of "carcinogen-induced repair DNA synthesis".
Topics: Acetoxyacetylaminofluorene; Animals; Bromodeoxyuridine; Carcinogens; Cell Nucleus; Cell Transformation, Neoplastic; DNA; DNA Repair; DNA Replication; Female; Hydroxyurea; Mitogens; Ovum; Thymidine; Xenopus | 1979 |
Bromodeoxyuridine mutagenesis and deoxyribonucleotide pool imbalance in mammalian cells.
Topics: Animals; Base Composition; Bromodeoxyuridine; Cell Line; Cricetinae; Cytarabine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Deoxyribonucleotides; DNA; Drug Resistance; Fluorouracil; Hydroxyurea; Melanoma; Mutation; Ribonucleotide Reductases; Sister Chromatid Exchange; Thymidine | 1985 |
Proliferation and maturation of bone marrow-derived lymphocytes.
Topics: Animals; Antibody-Producing Cells; B-Lymphocytes; Binding Sites, Antibody; Carbohydrates; Cell Division; Cell Separation; Cells, Cultured; Centrifugation; Dactinomycin; Hydroxyurea; Immunoglobulin Fab Fragments; Immunoglobulin Heavy Chains; Immunoglobulin M; Iodine Radioisotopes; Leucine; Lipopolysaccharides; Mice; RNA, Messenger; Spleen; Thymidine; Thymus Gland; Time Factors; Tritium | 1974 |
Synchronization of mammalian cells with respect to the mitotic cycle.
Topics: Animals; Antineoplastic Agents; Autoradiography; Calcium; Carbon Isotopes; Cattle; Cell Count; Cell Differentiation; Cell Line; Cells; Cells, Cultured; Centrifugation, Density Gradient; Clone Cells; Cold Temperature; Cricetinae; Culture Techniques; DNA; Female; Floxuridine; Guinea Pigs; HeLa Cells; Humans; Hydroxyurea; Iodine Isotopes; Kinetics; L Cells; Liver; Methods; Methotrexate; Mice; Mitosis; Ovary; RNA; Statistics as Topic; Thymidine; Time Factors; Tritium | 1971 |
Chemotherapy and the life cycle of leukaemic cells. A comparison between the growth characteristics of human acute leukaemia and the murine leukaemia L 1210.
Topics: Anilides; Animals; Cell Division; Cyclophosphamide; Cytarabine; DNA, Neoplasm; Fluorouracil; Humans; Hydroxyurea; In Vitro Techniques; Leukemia; Leukemia L1210; Leukemia, Lymphoid; Mechlorethamine; Mercaptopurine; Methotrexate; Mice; Mitosis; Nitroso Compounds; Prednisone; Thymidine; Time Factors; Tritium; Vinblastine; Vincristine | 1969 |
Radiosensitizing nucleosides.
Topics: Animals; Deoxycytidine; Gemcitabine; Humans; Hydroxyurea; Nucleosides; Pyrimidines; Radiation-Sensitizing Agents; Thymidine; Vidarabine | 1996 |
1 trial(s) available for thymidine and hydroxyurea
| Article | Year |
|---|---|
Clinical and biochemical studies of high-dose intermittent therapy of solid tumors with hydroxyurea (NSC-32065).
Topics: Adult; Aged; Blood Urea Nitrogen; Chondrosarcoma; Clinical Trials as Topic; Depression, Chemical; DNA, Neoplasm; Female; Humans; Hydroxyurea; In Vitro Techniques; Laryngeal Neoplasms; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukocytes; Leukopenia; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Male; Maxillary Neoplasms; Melanoma; Middle Aged; Nausea; Neoplasms; Spectrophotometry; Thrombocytopenia; Thymidine; Tongue Neoplasms; Tritium; Vomiting | 1970 |
494 other study(ies) available for thymidine and hydroxyurea
| Article | Year |
|---|---|
Evidence for stem cell function of resting bone marrow lymphocytes identified by the complete 3H-thymidine labelling method.
Topics: Animals; Animals, Newborn; Autoradiography; B-Lymphocytes; Cell Count; Cell Separation; Female; Hematopoiesis; Hematopoietic Stem Cell Transplantation; Hydroxyurea; Isotope Labeling; Peritoneal Cavity; Rats; Rats, Inbred Lew; Thymidine; Time Factors | 1975 |
Cell volume growth after cell cycle block with chemotherapeutic agents.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Bleomycin; Cell Division; Cell Line; Cells, Cultured; Colchicine; Cycloheximide; Cytarabine; Dactinomycin; Dose-Response Relationship, Drug; Hydroxyurea; Kinetics; Puromycin; Thymidine; Vinblastine | 1976 |
The mechanism of sensitivity to phleomycin in growing Escherichia coli cells.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Chloramphenicol; Cytarabine; DNA Repair; DNA Replication; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Hydroxyurea; Mitosis; Phenylethyl Alcohol; Phleomycins; Rifampin; RNA, Bacterial; Thymidine; Thymine; Time Factors; Tryptophan | 1976 |
Stimulatory effect of bleomycin on the synthesis of acidic glycosaminoglycans in cultured fibroblasts derived from rat carrageenin granuloma.
Topics: Acetylglucosaminidase; Animals; Bleomycin; Carrageenan; Cells, Cultured; Collagen; DNA; Dose-Response Relationship, Drug; Fibroblasts; Glucosamine; Glycoproteins; Glycosaminoglycans; Granuloma; Hydroxyurea; Proline; Rats; Sulfates; Thymidine | 1976 |
Cell surface changes in HeLa cells as an indication of cell cycle events.
Topics: Bleomycin; Cell Division; Cell Membrane; Cytarabine; HeLa Cells; Humans; Hydrocortisone; Hydroxyurea; Microscopy, Electron, Scanning; Mitomycins; Mitosis; Thymidine; Time Factors; Vinblastine | 1976 |
Aeration sensitizes Streptococcus faecalis to hydroxyurea.
Topics: Air; DNA, Bacterial; Enterococcus faecalis; Hydroxyurea; Thymidine | 1979 |
Effects of thymidine analogs upon growth control in cultured hormone-dependent ray ovary cells.
Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Culture Media; Cytarabine; Deoxyuridine; DNA; Female; Floxuridine; Hormones; Hydroxyurea; Idoxuridine; Kinetics; Ovarian Neoplasms; Rats; Thymidine | 1975 |
Giant pools of DNA precursors in sea urchin eggs.
Topics: Adenosine Triphosphate; Animals; Deoxyribonucleotides; DNA; Female; Fertilization; Floxuridine; Hydroxyurea; Mitosis; Sea Urchins; Thymidine; Thymine Nucleotides; Time Factors; Tritium; Zygote | 1975 |
Inhibitory effect of hydroxyurea on [3-H]leucine incorporation in human peripheral lymphocytes.
Topics: Animals; Blood Proteins; DNA; DNA Replication; Floxuridine; Humans; Hydroxyurea; Kinetics; Leucine; Lymphocytes; Phenylhydrazines; Protein Biosynthesis; Rabbits; Reticulocytes; Thymidine; Time Factors; Tritium | 1975 |
Control of normal differentiation of myeloid leukemic cells. VI. Inhibition of cell multiplication and the formation of macrophages.
Topics: Animals; Blood; Bromodeoxyuridine; Cell Adhesion; Cell Differentiation; Cell Division; Cell Movement; Clone Cells; Cycloheximide; Cytarabine; Dactinomycin; Endotoxins; Floxuridine; Hydroxyurea; Idoxuridine; Leukemia, Myeloid; Macrophages; Mice; Mitomycins; Thymidine; Vinblastine | 1975 |
DNA synthesis in growth and encystment of Acanthamoeba castellanii.
Topics: Animals; DNA; Eukaryota; Floxuridine; Hydroxyurea; Phosphates; Phosphorus Radioisotopes; RNA; Thymidine; Time Factors; Tritium | 1975 |
Changes in the organization of chromosomes during the cell cycle: response to ultraviolet light.
Topics: Autoradiography; Caffeine; Cell Division; Cell Fusion; Cell Survival; Chromosomes; Cytarabine; DNA, Neoplasm; Floxuridine; HeLa Cells; Humans; Hydroxyurea; Mitosis; Radiation Effects; Thymidine; Tritium; Ultraviolet Rays | 1975 |
Age-dependence of the x-ray-induced deficiency in DNA synthesis in HeLa S3 cells during Generation 1.
Topics: Aging; Cell Division; DNA; DNA, Neoplasm; Dose-Response Relationship, Radiation; Floxuridine; HeLa Cells; Hydroxyurea; Leucine; Mitosis; Protein Biosynthesis; Radiation Effects; Thymidine; X-Rays | 1975 |
Isotope-dilution studies of the effects of 5-fluorodeoxyuridine and hydroxyurea on the incorporation of deoxycytidine and thymidine by cultured thymus cells.
Topics: Animals; Cells, Cultured; Cytidine; Deoxyadenosines; Deoxycytidine; Deoxyribonucleosides; DNA Replication; Floxuridine; Hydroxyurea; Methotrexate; Rats; Thymidine; Thymus Gland | 1976 |
The reversible inhibition of myoblast fusion by ethidium bromide (EB).
Topics: Cell Fusion; Cells, Cultured; Chloramphenicol; Cytarabine; DNA; Dose-Response Relationship, Drug; Ethidium; Floxuridine; Hydroxyurea; Methotrexate; Protein Biosynthesis; Rifampin; RNA; Thymidine | 1976 |
DNA repair and frequency of x-ray and u.v.-light induced chromosome aberrations in leukocytes from patients with Down's syndrome.
Topics: Adult; Chromosome Aberrations; Chromosomes; DNA Repair; DNA Replication; Dose-Response Relationship, Radiation; Down Syndrome; Humans; Hydroxyurea; Leukocytes; Radiation Genetics; Thymidine; Ultraviolet Rays; X-Rays | 1976 |
Cell proliferation kinetics and drug sensitivity of exponential and stationary populations of cultured L1210 cells.
Topics: Amino Acids; Animals; Antineoplastic Agents; Carmustine; Cell Division; Cell Survival; Cells, Cultured; Culture Media; Cytarabine; Dactinomycin; Daunorubicin; DNA, Neoplasm; Doxorubicin; Glucose; Hydroxyurea; Kinetics; Leukemia L1210; Lomustine; Streptozocin; Thymidine; Vincristine | 1977 |
Survival of CHO cells that replicated DNA in the presence of hydroxyurea.
Topics: Cell Line; Cell Survival; Clone Cells; Cycloheximide; DNA; DNA Replication; Floxuridine; Hydroxyurea; Thymidine | 1977 |
Comparison of thymidine, fluorodeoxyuridine, hydroxyurea, and methotrexate blocking at the G1/S phase transition of the cell cycle, studied by replication patterns.
Topics: Amniotic Fluid; Cell Cycle; Cells, Cultured; Chromosomes, Human; DNA Replication; Floxuridine; History, 16th Century; Humans; Hydroxyurea; Interphase; Methotrexate; Skin; Thymidine | 1978 |
Effect of thymidine on poly(ADP-ribosyl)ation in vivo.
Topics: Cell Nucleus; DNA Replication; DNA, Neoplasm; HeLa Cells; Humans; Hydroxyurea; Kinetics; Methotrexate; Niacinamide; Nucleoside Diphosphate Sugars; Poly Adenosine Diphosphate Ribose; Thymidine | 1979 |
Nerve outgrowth by dorsal root ganglia in vitro: stimulation by inhibitors of DNA metabolism in the absence of exogenous nerve growth factor.
Topics: Animals; Arabinose; Cells, Cultured; Chick Embryo; Cytarabine; Cytosine; Dose-Response Relationship, Drug; Floxuridine; Ganglia, Spinal; Hydroxyurea; Nerve Growth Factors; Thymidine | 1979 |
Cell cycle and growth stage-dependent changes in the transport of nucleosides, hypoxanthine, choline, and deoxyglucose in cultured Novikoff rat hepatoma cells.
Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Division; Cells, Cultured; Choline; Demecolcine; Deoxyglucose; DNA; Glucose; Hydroxyurea; Hypoxanthines; Kinetics; Liver Neoplasms; Mitosis; Neoplasms, Experimental; Nucleosides; Rats; Receptors, Drug; RNA, Neoplasm; Spectrometry, Fluorescence; Thymidine; Time Factors; Tritium; Uridine | 1975 |
In vitro epidermal cell proliferation in rat skin plugs.
Topics: Aminophylline; Animals; Autoradiography; Bucladesine; Cell Division; Demecolcine; Depression, Chemical; DNA; Epinephrine; Hydroxyurea; Isoproterenol; Male; Mitosis; Models, Biological; Rats; Skin; Theophylline; Thymidine; Time Factors; Tritium; Wound Healing | 1975 |
Determination of limb bud chondrocytes during a transient block of the cell cycle.
Topics: Aminopterin; Animals; Bucladesine; Cartilage; Cell Adhesion; Cell Differentiation; Cell Division; Cells, Cultured; Chick Embryo; Colchicine; Cytarabine; DNA; Extremities; Floxuridine; Hydroxyurea; Theophylline; Thymidine | 1975 |
Regulation of hypoxanthine transport by cyclic nucleotides in cultured Chinese hamster lung fibroblasts.
Topics: Bucladesine; Cells, Cultured; Cyclic GMP; Cycloheximide; Dactinomycin; DNA; Fibroblasts; Glucagon; Hydroxyurea; Hypoxanthines; Insulin; Nucleotides, Cyclic; Theophylline; Thymidine; Xanthines | 1977 |
Transport and metabolism of deoxycytidine and 1-beta-D-arabinofuranosylcytosine into cultured Novikoff rat hepatoma cells, relationship to phosphorylation, and regulation of triphosphate synthesis.
Topics: Animals; Biological Transport, Active; Carcinoma, Hepatocellular; Cells, Cultured; Cytarabine; Deoxycytidine; Deoxyribonucleotides; DNA, Neoplasm; Feedback; Hydroxyurea; Liver Neoplasms; Neoplasms, Experimental; Oxidative Phosphorylation; Rats; Thymidine | 1978 |
Synthesis of globin mRNA in relation to the cell cycle during induced murine erythroleukemia differentiation.
Topics: Acetamides; Animals; Cell Cycle; Cell Differentiation; Cells, Cultured; Diamines; Dimethyl Sulfoxide; Globins; Hydroxyurea; Leukemia, Erythroblastic, Acute; Mice; Neoplasms, Experimental; RNA, Messenger; Thymidine | 1978 |
DNA repair in UV-irradiated heteroploid cells at different phases of the cell cycle.
Topics: Autoradiography; Cell Line; Cell Survival; DNA; DNA Repair; Humans; Hydroxyurea; Interphase; Mitosis; Thymidine; Ultraviolet Rays | 1978 |
Dissociation between proliferation and antibody formation by old mouse spleen cells in response to LPS stimulation.
Topics: Aging; Animals; Antibodies, Anti-Idiotypic; Antibody Formation; Dinitrobenzenes; Hydroxyurea; Immune Sera; Kinetics; Lipopolysaccharides; Lymphocyte Activation; Male; Mice; Spleen; Thymidine | 1979 |
Effect of hydroxyurea on radiation-induced division delay in CHO cells.
Topics: Animals; Cells, Cultured; Cricetinae; Cytological Techniques; DNA; Hydroxyurea; Mitosis; Thymidine; Time Factors; Tritium | 1977 |
Growth of animal cells on glass fiber filters and their utilization for biosynthetic analysis.
Topics: Cell Count; Cell Division; Cells, Cultured; Cytological Techniques; DNA; HeLa Cells; Hydroxyurea; Protein Biosynthesis; RNA; Thymidine | 1978 |
Excision of 4-nitroquinoline 1-oxide damage and transformed in mouse cells.
Topics: 4-Nitroquinoline-1-oxide; Adenine; Cell Transformation, Neoplastic; Cells, Cultured; DNA Repair; DNA, Neoplasm; Guanine; Hydroxyurea; Nitroquinolines; Thymidine; Xeroderma Pigmentosum | 1977 |
Cell synchronization.
Topics: Animals; Cell Cycle; Cell Line; Culture Media; Culture Techniques; DNA; Hydroxyurea; Isoleucine; Mitosis; Thymidine; Time Factors | 1979 |
Estrogen-induced prolactin and DNA synthesis in immature female rat pituitaries.
Topics: Animals; Deoxyribonucleases; DNA; Estradiol; Female; Hydroxyurea; Pituitary Gland, Anterior; Prolactin; Rats; Thymidine | 1979 |
DNA damage: a consequence of the combined effect of virus infection and incorporated radioactive thymidine.
Topics: Cell Line; Cell Transformation, Viral; Cycloheximide; Dactinomycin; DNA; DNA Repair; DNA, Viral; Humans; Hydroxyurea; Iridoviridae; Thymidine | 1979 |
Activation to IgG secretion by lipopolysaccharide requires several proliferation cycles.
Topics: Animals; Bromodeoxyuridine; Cell Cycle; DNA; Dose-Response Relationship, Immunologic; Female; Hydroxyurea; Immunoglobulin G; Immunoglobulin M; Kinetics; Lipopolysaccharides; Male; Mice; Mice, Inbred C3H; Mitosis; Thymidine | 1979 |
Cell cycle analysis of sodium butyrate and hydroxyurea, inducers of ectopic hormone production in HeLa cells.
Topics: Butyrates; Cell Cycle; Chorionic Gonadotropin; DNA; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; HeLa Cells; Humans; Hydroxyurea; Thymidine; Tritium | 1979 |
Differential lethal effects of both cytosine arabinoside and hydroxyurea on jejunal crypt cells and testosterone-stimulated accessory sex glands.
Topics: Animals; Castration; Cell Division; Cytarabine; DNA; Hydroxyurea; Jejunum; Male; Rats; Seminal Vesicles; Testosterone; Thymidine; Tritium | 1979 |
Lethal and sublethal effects of hydroxyurea in relation to drug concentration and duration of drug exposure in sarcoma 180 in vitro.
Topics: Animals; Autoradiography; Cell Division; Cell Survival; Clone Cells; DNA, Neoplasm; Drug Administration Schedule; Hydroxyurea; Sarcoma 180; Thymidine; Time Factors; Tritium | 1977 |
Replication of equine herpesvirus type 1 and type 3: resistance to hydroxyurea and thymidine.
Topics: Animals; Cells, Cultured; Centrifugation, Isopycnic; DNA, Viral; Drug Resistance, Microbial; Herpesviridae; Horses; Hydroxyurea; Thymidine; Virus Replication | 1978 |
Mutagenicity of thymidine to cultured Chinese hamster cells.
Topics: Animals; Cell Line; Cricetinae; Deoxycytidine; Dose-Response Relationship, Drug; Hydroxyurea; Mutation; Thymidine | 1978 |
Proliferative state of normal in vitro colony-forming cells during development of L5222 rat leukemia and their reaction to chemotherapy.
Topics: Animals; Bone Marrow Cells; Cell Division; Cell Survival; Cells, Cultured; Daunorubicin; Female; Hydroxyurea; Leukemia, Experimental; Rats; Thymidine; Time Factors | 1978 |
DNA repair in normal and preneoplastic mammary tissues.
Topics: Animals; Bromodeoxyuridine; DNA Repair; DNA Replication; DNA, Neoplasm; Female; Hydroxyurea; In Vitro Techniques; Mammary Neoplasms, Experimental; Methyl Methanesulfonate; Mice; Mice, Inbred BALB C; Precancerous Conditions; Pregnancy; Thymidine | 1978 |
Hydroxyurea-sensitive thymidine incorporation in rat liver and kidney following administration of dimethylnitrosamine.
Topics: Animals; Dimethylnitrosamine; DNA; DNA Repair; DNA Replication; Female; Hydroxyurea; Kidney; Liver; Nitrosamines; Rats; Thymidine | 1978 |
Mapping G1 phase by the structural morphology of the prematurely condensed chromosomes.
Topics: Cell Cycle; Cell Fusion; Cell Line; Cell Transformation, Neoplastic; Chromosomes; Cycloheximide; Dactinomycin; Hydroxyurea; Interphase; Thymidine | 1978 |
Tissue specificity for incorporation of [3H]thymidine by the 10- to 12-somite mouse embryo: alteration by acute exposure to hydroxyurea.
Topics: Animals; Cell Nucleus; Embryo, Mammalian; Hydroxyurea; Mice; Thymidine; Tissue Distribution | 1978 |
Chemical induction of unscheduled DNA synthesis in human skin epithelial cell cultures.
Topics: Arginine; Carcinogens; Cells, Cultured; DNA; DNA Repair; Epithelium; Humans; Hydroxyurea; Scintillation Counting; Skin; Thymidine; Tritium | 1978 |
3' deoxycytidine, like hydroxyurea, inhibits DNA synthesis without preventing the initiation of the cell cycle.
Topics: Cell Cycle; Cell Line; Deoxycytidine; DNA; Hydroxyurea; RNA; Thymidine | 1978 |
Stimulation by amphotericin B of uridine transport, RNA synthesis and DNA synthesis in density-inhibited fibroblasts.
Topics: Adenosine; Amphotericin B; Biological Transport; Cell Line; Cell Survival; Contact Inhibition; Dactinomycin; DNA; Hydroxyurea; RNA; Thymidine; Uridine | 1978 |
Separate effect of hydroxyurea on the initiation and elongation of DNA synthesis in BHK cells.
Topics: Cell Cycle; Cell Line; DNA; Hydroxyurea; Kinetics; Thymidine | 1978 |
Effect of inhibition of DNA synthesis on histone synthesis and deposition.
Topics: Cell Line; Cell Nucleus; Chromatin; DNA; DNA Replication; Histones; Hydroxyurea; Kinetics; Thymidine | 1978 |
In vivo synchronization of murine sarcoma 37 ascites tumor cells by use of hydroxyurea.
Topics: Animals; Cell Division; Cytological Techniques; DNA Replication; DNA, Neoplasm; Hydroxyurea; Mice; Sarcoma 37; Thymidine; Time Factors | 1976 |
Evidence of repair of DNA damage induced by 4-hydroxyaminoquinoline 1-oxide in guinea pig pancreatic slices in vitro.
Topics: 4-Hydroxyaminoquinoline-1-oxide; 4-Nitroquinoline-1-oxide; Aminoquinolines; Animals; Carcinogens; DNA Replication; Dose-Response Relationship, Drug; Guinea Pigs; Hydroxyurea; In Vitro Techniques; Kinetics; Pancreas; Regeneration; Thymidine; Time Factors | 1976 |
Nucleocytoplasmic ratio requirements for the initiation of DNA replication and fission in Tetrahymena.
Topics: Animals; Cell Division; Chromatin; Cytoplasm; DNA; DNA Replication; Hydroxyurea; Organoids; Tetrahymena pyriformis; Thymidine | 1976 |
The effect of papaverine on the fate of thymidine phosphates in isolated mouse thymus cells.
Topics: Animals; Hydroxyurea; Kinetics; Male; Mice; Mice, Inbred BALB C; Papaverine; Thymidine; Thymine; Thymine Nucleotides; Thymus Gland | 1977 |
Differential cytotoxicity between transformed and normal human cells with combinations of aminonucleoside and hydroxyurea.
Topics: Cell Division; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Hydroxyurea; Puromycin; Puromycin Aminonucleoside; RNA; Thymidine | 1977 |
Biochemical analysis of meiosis in the male mouse. I. Separation of DNA labelling of specific spermatogenic stages.
Topics: Animals; DNA; Hydroxyurea; Male; Meiosis; Mice; Spermatogenesis; Thymidine; Tritium | 1977 |
Ultraviolet-induced DNA-repair synthesis in lymphocytes from patients with chronic lymphatic leukemia.
Topics: Aged; DNA Repair; DNA Replication; DNA, Neoplasm; Female; Humans; Hydroxyurea; Leukemia, Lymphoid; Lymphocytes; Male; Middle Aged; Thymidine; Ultraviolet Rays | 1977 |
Hydroxyurea (HU) in experimental hematology. II. Similarities and dissimilarities between HU and 3H-thymidine killing.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Count; Cell Division; Cells, Cultured; Clone Cells; Culture Media; Cyclophosphamide; Female; Hydroxyurea; Male; Mice; Thymidine | 1977 |
Comparison of hydroxyurea and excess thymidine as synchronizing agents in cultures of L5178Y mouse lymphoma cells.
Topics: Animals; Carbon Radioisotopes; Cell Cycle; Cell Membrane Permeability; Cells, Cultured; DNA, Neoplasm; Hydroxyurea; Lymphoma; Mice; Mice, Inbred Strains; Mitosis; Thymidine | 1977 |
S phase synchrony in monolayer CHO cultures.
Topics: Cell Division; Cell Line; Culture Media; DNA; Hydroxyurea; Isoleucine; Kinetics; Mitosis; Protein Biosynthesis; RNA; Thymidine; Time Factors; Uridine | 1976 |
Cell division and deoxyribonucleic acid (DNA) synthesis in cultures of stimulated lymphocytes.
Topics: Animals; Concanavalin A; DNA; Dogs; Female; Hydroxyurea; In Vitro Techniques; Lectins; Lymphocyte Activation; Lymphocytes; Male; Mice; Mitosis; Spleen; Thymidine; Time Factors | 1976 |
Study of in vivo tumor state and response to therapy by analysis of DNA distribution.
Topics: Animals; Carmustine; Cell Survival; Cobalt Radioisotopes; DNA, Neoplasm; Female; Hydroxyurea; Kinetics; Lymphoma; Mechlorethamine; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Radioisotope Teletherapy; Thymidine | 1976 |
Effect of iron deficiency and desferrioxamine on DNA synthesis in human cells.
Topics: Anemia, Hypochromic; Deferoxamine; Deoxyribonucleosides; DNA; Female; Humans; Hydroxyurea; Lymphocyte Activation; Lymphocytes; Male; Ribonucleotide Reductases; Thymidine; Thymidine Kinase; Time Factors | 1976 |
[DNA synthesis in the brain and liver of rats in various stages of postnatal development].
Topics: Age Factors; Animals; Brain; Carbon Radioisotopes; DNA; Hydroxyurea; Liver; Neuroglia; Neurons; Rats; Thymidine; Tritium | 1976 |
Interferon synthesis in mouse peritoneal cells damaged by X-irradiation.
Topics: Amino Acids; Animals; Ascitic Fluid; Cell Count; Cells, Cultured; Dactinomycin; Hydroxyurea; Interferons; Mice; Mitomycins; Newcastle disease virus; Puromycin; Thymidine; Uridine; X-Rays | 1976 |
Cell cycle studies of mononucleate and cytochalasin-B--nduced binucleate fibroblasts.
Topics: Animals; Cell Division; Cell Line; Cell Nucleus; Cricetinae; Cytochalasin B; DNA; Fibroblasts; Hydroxyurea; Kidney; Kinetics; Mitosis; Thymidine | 1975 |
Cell kill kinetics with hydroxyurea.
Topics: Cell Count; Cell Line; Cell Survival; DNA Replication; Humans; Hydroxyurea; Leukemia, Myeloid; Mitosis; Mitotic Index; Thymidine; Trypan Blue | 1976 |
DNA synthesis in rabbit spleen explants. Its relationship to cell division.
Topics: Animals; Antibody-Producing Cells; Cell Division; Cell Nucleus; Cells, Cultured; Culture Media; Demecolcine; Densitometry; DNA; DNA Repair; Female; Guinea Pigs; Hemolytic Plaque Technique; Hydroxyurea; Male; Mice; Rabbits; Spleen; Thymidine | 1975 |
Studies on the mechanism of replication of adenovirus DNA. IV. Discontinuous DNA Chain propagation.
Topics: Adenoviridae; Carcinoma; Cell Line; Centrifugation, Zonal; DNA Replication; Hydroxyurea; Mouth Neoplasms; Nucleic Acid Hybridization; Thymidine; Tritium; Virus Replication | 1975 |
Effects of double and multiple doses of hydroxyurea on mouse duodenum and mammary tumors.
Topics: Animals; Body Weight; Cell Division; DNA; DNA, Neoplasm; Duodenum; Hydroxyurea; Kinetics; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Thymidine; Time Factors | 1975 |
[Excision repair in lymphocytes of psoriasis (author's transl)].
Topics: Adult; Carcinogens; DNA Repair; Female; Humans; Hydroxyurea; In Vitro Techniques; Lymphocytes; Male; Middle Aged; Models, Biological; Mutagens; Psoriasis; Radiation Effects; Thymidine; Tritium; Ultraviolet Rays | 1975 |
DNA repair synthesis following exposure of guinea-pig pancreatic slices to methyl-N-nitrosourethane in vitro.
Topics: Animals; DNA; DNA Repair; DNA Replication; Guinea Pigs; Hydroxyurea; Male; Nitroso Compounds; Pancreas; Stimulation, Chemical; Thymidine; Tritium; Urethane | 1975 |
Sequential irreversible, actinomycin D-sensitive, and cycloheximide-sensitive steps prior to cortisol inhibition of uridine utilization by P1798 tumor lymphocytes.
Topics: Animals; Cycloheximide; Dactinomycin; Depression, Chemical; Female; Hydrocortisone; Hydroxyurea; Lymphocytes; Mice; Mice, Inbred BALB C; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Phenylalanine; Protein Biosynthesis; RNA; RNA, Neoplasm; Thymidine; Time Factors; Transcription, Genetic; Uridine | 1975 |
Investigations into the inhibition of DNA repair processes by detergents.
Topics: Animals; Autoradiography; Depression, Chemical; Detergents; DNA Repair; DNA Replication; Ethers; Hydroxyurea; Mice; Polyethylene Glycols; Polysorbates; Spleen; Thymidine | 1975 |
Inhibition of 3H-thymidine incorporation by hydroxyurea: atpical response of mycoplasma-infected cells in culture.
Topics: Animals; Cell Line; DNA Replication; DNA, Neoplasm; HeLa Cells; Humans; Hydroxyurea; Mammary Neoplasms, Experimental; Mycoplasma; Neoplasms, Experimental; Neurilemmoma; Rats; Thymidine; Time Factors; Tritium | 1975 |
Absence of specificity in inhibition of DNA repair replication by DNA-binding agents, cocarcinogens, and steroids in human cells.
Topics: Animals; Bromodeoxyuridine; Carcinogens; Centrifugation, Density Gradient; Cyanides; Dimethyl Sulfoxide; DNA; DNA Repair; DNA Replication; Dogs; HeLa Cells; Humans; Hydroxyurea; Lymphocytes; Progesterone; Quinacrine; Radiation Effects; Thymidine; Ultraviolet Rays; Vitamin A | 1975 |
Evaluation of S phase synchronizotaation by analysis of DNA replication in 5-bromodeoxyuridine.
Topics: Animals; Bromodeoxyuridine; Cell Division; Cell Line; Centrifugation, Density Gradient; Cricetinae; DNA; DNA Replication; Female; Hydroxyurea; Mitosis; Ovary; Thymidine; Time Factors | 1975 |
Some evidence for replication-transcription coupling in Physarum polycephalum.
Topics: Chromatin; Cycloheximide; DNA; DNA Replication; Hybridization, Genetic; Hydroxyurea; Mitosis; Myxomycetes; Physarum; RNA; Templates, Genetic; Thymidine; Transcription, Genetic; Uridine | 1975 |
Effect of calcium and magnesium on deoxyribonucleic acid synthesis in rat parathyroid glands in vitro.
Topics: Animals; Autoradiography; Calcium; Deoxycytidine; DNA; Humans; Hydroxyurea; Hyperplasia; Kidney; Kidney Failure, Chronic; L Cells; Liver; Magnesium; Male; Mice; Organ Culture Techniques; Parathyroid Diseases; Parathyroid Glands; Rats; Thymidine | 1975 |
Matrix simulation of duodenal crypt cell kinetics. I. The steady state.
Topics: Animals; Cell Count; Cell Division; Cells, Cultured; Duodenum; Hydroxyurea; Isotope Labeling; Kinetics; Mathematics; Mice; Mice, Inbred C3H; Mitosis; Models, Biological; Thymidine; Tritium | 1975 |
Matrix simulation of duodenal crypt cell kinetics. II. Cell kinetics following hydroxyurea.
Topics: Animals; Cell Count; Cell Division; Cell Survival; Cells, Cultured; Duodenum; Hydroxyurea; Intestinal Mucosa; Isotope Labeling; Kinetics; Mathematics; Mice; Mice, Inbred C3H; Mitosis; Models, Biological; Thymidine; Tritium | 1975 |
[Effect of naproxen on DNA synthesis and DNA repair of human lymphocytes in in vivo experiments].
Topics: Arthritis, Rheumatoid; Chronic Disease; Cobalt Radioisotopes; DNA; DNA Repair; Humans; Hydroxyurea; Lymphocytes; Middle Aged; Naphthaleneacetic Acids; Naproxen; Prednisolone; Radiation Effects; Thymidine; Tritium | 1975 |
Differential permeability of murine visceral yolk sac to thymidine and to hydroxyurea.
Topics: Animals; Biological Transport; Cell Nucleus; Female; Gestational Age; Hydroxyurea; Mice; Permeability; Pregnancy; Thymidine; Vitelline Membrane | 1975 |
[Acute cell death in various sections of the gastrointestinal tract in DNA synthesis inhibition].
Topics: Animals; Autoradiography; Cell Survival; Digestive System; DNA; Dose-Response Relationship, Drug; Drug Tolerance; Epithelial Cells; Epithelium; Hydroxyurea; Mice; Necrosis; Thymidine; Time Factors | 1975 |
Differential effects of isoleucine deprivation on cell motility, membrane transport and DNA synthesis in NIL 8 hamster cells.
Topics: Biological Transport, Active; Blood; Cell Division; Cell Line; Cell Membrane; Cell Movement; Cell Survival; Culture Media; Deoxyglucose; DNA; Hydroxyurea; Isoleucine; Thymidine; Uridine | 1975 |
Hydroxyurea does not prevent synchronized G1 chinese hamster cells from entering the DNA synthetic period.
Topics: Cell Line; Centrifugation, Density Gradient; DNA; DNA Replication; Hydroxyurea; Mitosis; Molecular Weight; Thymidine; Time Factors | 1976 |
Induction of DNA polymerase alpha during liver regeneration in rats on controlled feeding schedules.
Topics: Animals; Cell Nucleus; Chromatography, DEAE-Cellulose; Cycloheximide; Dactinomycin; DNA; DNA Nucleotidyltransferases; Eating; Enzyme Induction; Ethylmaleimide; Hepatectomy; Hydroxyurea; Liver Regeneration; Male; Rats; Thymidine | 1976 |
DNA repair synthesis in guinea pig pancreatic slices following in vitro exposure to N-nitrosomethylurethane.
Topics: Animals; DNA Repair; DNA Replication; Guinea Pigs; Hydroxyurea; In Vitro Techniques; Kinetics; Male; Nitrosomethylurethane; Pancreas; Thymidine; Urethane | 1976 |
Importance of pyrimidine nucleotide salvage pathways for DNA synthesis in skin.
Topics: Animals; Animals, Newborn; Azauridine; Cytidine; DNA; Hydroxyurea; Liver; Methotrexate; Mice; Orotic Acid; Pyrimidine Nucleotides; Rabbits; RNA; Skin; Thymidine; Time Factors; Uridine | 1976 |
A technique for determining the proportion of the clonogenic cells in S phase in ENT6 cell cultures and tumors.
Topics: Animals; Cell Division; Cell Line; Cell Survival; Clone Cells; Female; Hydroxyurea; Kinetics; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Thymidine; Tritium | 1976 |
Compartmentation of dCTP pools disappears after hydroxyurea or araC treatment in lymphocytes.
Topics: Cytarabine; Deoxycytidine; Deoxycytosine Nucleotides; DNA; G1 Phase; Humans; Hydroxyurea; Lymphocytes; Palatine Tonsil; Phospholipids; S Phase; Thymidine | 1992 |
Induction of DNA-repair synthesis (UDS) in rat pleural mesothelial cells by urine of subjects exposed to genotoxic agents.
Topics: Adult; Animals; Cells, Cultured; Chromium; DNA Repair; DNA Replication; Epithelium; Humans; Hydroxyurea; Middle Aged; Mutagenicity Tests; Neoplasms; Occupational Exposure; Pleura; Rats; Smoking; Thiocyanates; Thymidine; Urine | 1992 |
Omeprazole does not cause unscheduled DNA synthesis in rabbit parietal cells in vitro.
Topics: Animals; Autoradiography; DNA; Glucose; Histamine; Hydroxyurea; In Vitro Techniques; Male; Methylnitronitrosoguanidine; Omeprazole; Oxidation-Reduction; Parietal Cells, Gastric; Rabbits; Ranitidine; Thymidine; Ultraviolet Rays | 1992 |
Role of viral ribonucleotide reductase in the increase of dTTP pool size in herpes simplex virus-infected Vero cells.
Topics: Animals; Chromosome Deletion; Floxuridine; Hydroxyurea; Kinetics; Phosphorylation; Ribonucleotide Reductases; Simplexvirus; Thymidine; Thymine Nucleotides; Vero Cells; Virus Replication | 1991 |
Growth and differentiation of pancreatic acinar cells: independent effects of glucocorticoids on AR42J cells.
Topics: Adrenal Cortex Hormones; Aldosterone; Amylases; Animals; Cell Differentiation; Cell Division; Cells, Cultured; Dexamethasone; DNA; Dose-Response Relationship, Drug; Epidermal Growth Factor; Glucocorticoids; Hydroxyurea; Insulin; Pancreas; Progesterone; Rats; Thymidine; Tritium | 1991 |
Organ culture as a model for investigating the effects of antimetabolites and nucleoside transport inhibitors on rodent colonic mucosa.
Topics: Animals; Biological Transport; Colon; Dipyridamole; DNA; Hydroxyurea; Intestinal Mucosa; Male; Models, Biological; Nucleosides; Organ Culture Techniques; Pyrimidines; Rats; Rats, Inbred Strains; Thioinosine; Thymidine; Time Factors; Tritium; Uridine | 1991 |
Differences in the kinetics of DNA repair in cancer patients and healthy controls.
Topics: Anemia, Aplastic; Breast Neoplasms; DNA Repair; Female; Humans; Hydroxyurea; In Vitro Techniques; Kinetics; Lymphocytes; Reference Values; Thymidine; Ultraviolet Rays; Xeroderma Pigmentosum | 1991 |
Efficient introduction of a gene into hematopoietic cells in S-phase by electroporation.
Topics: Aphidicolin; beta-Galactosidase; Bromodeoxyuridine; Cell Line; Diterpenes; DNA Polymerase II; Flow Cytometry; Gene Expression; Hematopoietic Stem Cells; Humans; Hydroxyurea; Plasmids; Propidium; S Phase; Thymidine; Transfection | 1991 |
Effects of thymidine and hydroxyurea on the metabolism and cytotoxicity of 1-B-D arabinofuranosylcytosine in highly resistant human leukemia cells.
Topics: Arabinofuranosylcytosine Triphosphate; Cell Cycle; Cell Survival; Cytarabine; DNA; Drug Resistance; Humans; Hydroxyurea; In Vitro Techniques; Leukemia, Myeloid; Thymidine; Tumor Cells, Cultured | 1991 |
Growth of normal human hepatocytes in primary culture: effect of hormones and growth factors on DNA synthesis.
Topics: Animals; Arginine Vasopressin; Cell Division; Cells, Cultured; DNA; Epidermal Growth Factor; Growth Substances; Hormones; Humans; Hydroxyurea; Liver; Reference Values; Thymidine; Transforming Growth Factor alpha; Transforming Growth Factor beta | 1991 |
Modified method of mammalian cell synchronization improves yield and degree of synchronization.
Topics: Animals; Cell Adhesion; Cell Cycle; Cells, Cultured; Cricetinae; Cricetulus; HeLa Cells; Hydroxyurea; Thymidine | 1991 |
Deoxyadenosine reverses hydroxyurea inhibition of vaccinia virus growth.
Topics: Adenine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Antiviral Agents; Cells, Cultured; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Hydroxyurea; Ribonucleotide Reductases; Thymidine; Vaccinia virus; Viral Plaque Assay; Virus Replication | 1991 |
DNA damage, repair, and replication in selenite-induced cataract in rat lens.
Topics: Animals; Cataract; Chromatography; DNA; DNA Damage; DNA Repair; DNA Replication; Hydroxyurea; Lens, Crystalline; Rats; Rats, Inbred Strains; Selenium; Selenium Compounds; Selenium Oxides; Thymidine | 1990 |
Kinetics of the development of accelerated cell-cycle transit resulting from inhibition of DNA replication in the previous cycle.
Topics: Antineoplastic Agents; Aphidicolin; Cell Cycle; Cytarabine; Diterpenes; DNA; DNA Polymerase II; DNA Replication; HeLa Cells; Humans; Hydroxyurea; Interphase; Mitosis; Thymidine | 1990 |
The nature of the embryo-protective interaction of propyl gallate with hydroxyurea.
Topics: Abnormalities, Drug-Induced; Animals; DNA; Embryo, Mammalian; Female; Hydroxyurea; Injections; Necrosis; Pregnancy; Propyl Gallate; Rabbits; Thymidine; Uterus | 1990 |
Development of the "activated" high resolution 1H MR spectrum in murine T cells and B cells occurs in G1 phase of the cell cycle.
Topics: Adenocarcinoma; Animals; B-Lymphocytes; Cells, Cultured; Deferoxamine; G1 Phase; Hydroxyurea; Lymphocyte Activation; Magnetic Resonance Spectroscopy; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Rats; Spleen; T-Lymphocytes; Thymidine; Tritium; Tumor Cells, Cultured | 1990 |
Isolated Coxiella burnetii synthesizes DNA during acid activation in the absence of host cells.
Topics: Blotting, Southern; Chloramphenicol; Coxiella; Culture Media; DNA, Bacterial; Hydrogen-Ion Concentration; Hydroxyurea; Rifamycins; Thymidine | 1990 |
[3H]thymidine incorporation does not correlate with growth state in cultured alveolar type II cells.
Topics: Animals; Cell Division; Cells, Cultured; DNA; Fibroblasts; Hydroxyurea; Kinetics; Male; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Thymidine; Thymidine Kinase | 1990 |
Effects of aphidicolin and/or 2',3'-dideoxythymidine on DNA repair induced in HeLa cells by four types of DNA-damaging agents.
Topics: Aphidicolin; Bleomycin; Dideoxynucleosides; Diterpenes; DNA Polymerase I; DNA Polymerase II; DNA Repair; HeLa Cells; Humans; Hydroxyurea; Kinetics; Sulfuric Acid Esters; Thymidine; Ultraviolet Rays; Zinostatin | 1985 |
Stimulation of protein accumulation in HeLa cells by inhibitors of DNA replication. Ferritin.
Topics: Aphidicolin; Azacitidine; Butyrates; Butyric Acid; Diterpenes; DNA Polymerase II; Ferritins; HeLa Cells; Humans; Hydroxyurea; Interphase; Iron; Thymidine | 1985 |
Increase of extrachromosomal circular DNA in mouse 3T6 cells on perturbation of DNA synthesis: implications for gene amplification.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aphidicolin; Blotting, Southern; Cells, Cultured; Cycloheximide; Cytoplasm; Diterpenes; DNA; DNA, Circular; DNA, Mitochondrial; Gene Amplification; Hydroxyurea; Mice; Thymidine | 1989 |
G2 effects of DNA-repair inhibitors on chromatid-type aberrations in root-tip cells treated with maleic hydrazide and mitomycin C.
Topics: Caffeine; Cell Cycle; Chromosome Aberrations; Chromosomes; Cytarabine; DNA Damage; DNA Repair; Floxuridine; Hydroxyurea; In Vitro Techniques; Interphase; Maleic Hydrazide; Mitomycin; Mitomycins; Plants; Pyridazines; Thymidine | 1989 |
Deoxyribonucleoside triphosphate pools in regenerating rat liver: effect of hydroxyurea and exogenous deoxypyrimidines.
Topics: Animals; Deoxycytidine; Deoxyribonucleotides; DNA; Hepatectomy; Hydroxyurea; Kinetics; Liver; Liver Regeneration; Male; Rats; Rats, Inbred Strains; Reference Values; Thymidine | 1989 |
Synergistic effects of hydroxyurea and thymidine on the growth inhibition of V79 cells.
Topics: Animals; Cell Division; Cricetinae; Cricetulus; DNA; Drug Synergism; Flow Cytometry; Growth Inhibitors; Hydroxyurea; Lung; Thymidine | 1989 |
[Deoxyribonucleic acid synthesis by rat thymus and spleen cells in vitro following hyperthermia].
Topics: Animals; Benzamides; Cytarabine; Dideoxynucleosides; DNA; Female; Hot Temperature; Hydroxyurea; Novobiocin; Rats; Spleen; Thymidine; Thymus Gland; Topoisomerase II Inhibitors | 1988 |
Excision repair in xeroderma pigmentosum group C cells is regulated differently in transformed cells and primary fibroblasts.
Topics: Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; DNA Repair; DNA Replication; Fibroblasts; Herpesvirus 4, Human; Humans; Hydroxyurea; Reference Values; Simian virus 40; Thymidine; Ultraviolet Rays; Xeroderma Pigmentosum | 1988 |
The herpes simplex virus type 1 temperature-sensitive mutant ts1222 has a single base pair deletion in the small subunit of ribonucleotide reductase.
Topics: Amino Acid Sequence; Base Sequence; Chromosome Deletion; Culture Media; DNA, Viral; Genes, Viral; Hydroxyurea; Molecular Sequence Data; Mutation; Ribonucleotide Reductases; Simplexvirus; Temperature; Thymidine; Virus Replication | 1988 |
Thymidine suicide and hydroxyurea kill ratios accurately reflect the proliferative status of stem cells (CFU-S).
Topics: Animals; Cell Division; Cell Survival; DNA Replication; Female; Hematopoietic Stem Cells; Hydroxyurea; Male; Mice; Mice, Inbred Strains; Thymidine | 1989 |
The sources of thymidine nucleotides for virus DNA synthesis in herpes simplex virus type 2-infected cells.
Topics: Animals; Cell Line; Chlorocebus aethiops; DNA; DNA, Viral; HeLa Cells; Humans; Hydroxyurea; Kidney; Ribonucleotide Reductases; Simplexvirus; Thymidine; Thymine Nucleotides | 1985 |
Effects of DNA and prostaglandin synthesis inhibitors on the stimulation of bone resorption by epidermal growth factor in fetal rat long-bone cultures.
Topics: Animals; Aphidicolin; Bone Resorption; Diterpenes; DNA Replication; Epidermal Growth Factor; Female; Hydroxyurea; Indomethacin; Organ Culture Techniques; Parathyroid Hormone; Pregnancy; Prostaglandins; Rats; Thymidine | 1986 |
D-ribose inhibits DNA repair synthesis in human lymphocytes.
Topics: Arabinose; DNA Repair; Gamma Rays; Humans; Hydroxyurea; Kinetics; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Ribose; Thymidine | 1986 |
Appearance of plasminogen activator activity during a synchronous cycle of a rat adenocarcinoma cell line, PA-III.
Topics: Adenocarcinoma; Animals; Cell Cycle; Cell Line; Clone Cells; DNA Replication; Hydroxyurea; Kinetics; Male; Prostatic Neoplasms; Rats; Thymidine; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator | 1987 |
Synergistic effect of hydroxyurea and excessive thymidine on the expression of the common fragile sites at 3p14 and 16q23.
Topics: Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 3; Drug Synergism; Humans; Hydroxyurea; Thymidine | 1988 |
Kinetics of replicon initiation during S phase of Chinese hamster ovary cells.
Topics: Animals; Cell Line; Cricetinae; Cricetulus; DNA Replication; Female; Hydroxyurea; Interphase; Kinetics; Ovary; Replicon; Thymidine; Trioxsalen | 1988 |
An in vivo study on the synchronizing effect of hydroxyurea.
Topics: Animals; Autoradiography; Carbon Radioisotopes; Cell Cycle; Cell Division; DNA Replication; Female; Hydroxyurea; Kinetics; Leukemia L1210; Mice; Mice, Inbred Strains; Thymidine; Tritium | 1988 |
Nonrandom assembly of chromatin during hydroxyurea inhibition of DNA synthesis.
Topics: Animals; Cell Line; Chickens; Chromatin; DNA Replication; Histones; Hydroxyurea; Kinetics; Nucleosomes; Thymidine | 1988 |
Hyperthermia blocks reversibility of hydroxyurea and bipyridine induced synergistic inhibition of DNA biosynthesis in P388 murine leukemia cells.
Topics: 2,2'-Dipyridyl; Animals; DNA Replication; Drug Synergism; Hot Temperature; Hydroxyurea; Kinetics; Leukemia P388; Leukemia, Experimental; Mice; Pyridines; Thymidine | 1988 |
Aluminum effects on growth of brain microvessel endothelial cells in primary culture.
Topics: Aluminum; Animals; Cattle; Cells, Cultured; Cerebrovascular Circulation; Endothelium, Vascular; Hydroxyurea; Microcirculation; Thymidine | 1988 |
Enhancement by hemin of the sensitivity of K562 human leukemic cells to 1-beta-D-arabinofuranosylcytosine.
Topics: Aminolevulinic Acid; Butyrates; Cell Differentiation; Cell Line; Cytarabine; Daunorubicin; Deoxyguanosine; Doxorubicin; Drug Synergism; Erythropoiesis; Heme; Hemin; Humans; Hydroxyurea; Leukemia, Myeloid; Methotrexate; Thymidine; Vincristine | 1986 |
Life span of B lymphocytes: the experimental basis for conflicting results.
Topics: Animals; B-Lymphocytes; Cell Cycle; Cell Movement; Cell Survival; Hydroxyurea; Immunization, Passive; Lipopolysaccharides; Lymphocyte Activation; Lymphocyte Depletion; Lymphoid Tissue; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Stress, Physiological; Thymidine; Time Factors | 1986 |
Factors influencing ADP-ribosylation differences between chromosomal proteins of interphase and metaphase HeLa cells.
Topics: Adenosine Diphosphate Ribose; Animals; Benzimidazoles; Cell Line; Cell Nucleus; Chromatin; Chromosomal Proteins, Non-Histone; Chromosomes; Cycloheximide; Deoxyadenosines; DNA Damage; HeLa Cells; Humans; Hydroxyurea; Interphase; Isoelectric Point; Metaphase; Molecular Weight; NAD; Nocodazole; Rats; Thymidine | 1987 |
Influence of hydroxyurea on lectin-induced early and late events in peripheral blood lymphocyte cultures.
Topics: Adenine; Animals; B-Lymphocytes; Cells, Cultured; Fluorescence; Humans; Hydroxyurea; Immunoglobulins; Lectins; Lymphocyte Activation; Lymphocytes; Mitogens; Thymidine; Uridine | 1987 |
Induction of glycoprotein biosynthesis in activated B lymphocytes.
Topics: Animals; B-Lymphocytes; DNA Replication; Glycoproteins; Glycosylation; Hydroxyurea; Interphase; Mannose; Mice; Mice, Inbred DBA; Thymidine; Uridine | 1987 |
Isolation of an autocrine growth factor from hepatoma HTC-SR cells.
Topics: Animals; Chromatography, Affinity; DNA Replication; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Growth Substances; Hepatocyte Growth Factor; Hot Temperature; Hydroxyurea; Liver Neoplasms, Experimental; Rats; Thymidine; Time Factors | 1987 |
Reduced DNA repair synthesis in healthy women having first degree relatives with breast cancer.
Topics: Adult; Aged; Breast Neoplasms; DNA Repair; Female; Humans; Hydroxyurea; Menopause; Middle Aged; Risk; Thymidine | 1987 |
[Repair in the nuclear matrix of DNA damaged by benz(a)pyrene].
Topics: Animals; Benzo(a)pyrene; Cell Fractionation; Cell Nucleus; Cells, Cultured; DNA; DNA Damage; DNA Repair; Hydroxyurea; Thymidine; Time Factors; Tritium | 1987 |
Utilization of hydroxyurea for detection of DNA repair synthesis in liver following dimethylnitrosamine action by means of scintillation counting.
Topics: Animals; Dimethylnitrosamine; DNA Repair; DNA Replication; Hydroxyurea; Liver; Male; Mice; Mice, Inbred Strains; Scintillation Counting; Thymidine; Tritium | 1987 |
Analysis of the G1 arrest position of senescent WI38 cells by quinacrine dihydrochloride nuclear fluorescence. Evidence for a late G1 arrest.
Topics: Blood; Cell Line; Cell Nucleus; Cell Survival; Culture Media; Humans; Hydroxyurea; Interphase; Microscopy, Fluorescence; Quinacrine; Thymidine | 1986 |
Impaired DNA-repair synthesis in lymphocytes of breast cancer patients.
Topics: Adult; Aged; Breast Neoplasms; DNA; DNA Repair; Female; Humans; Hydroxyurea; Lymphocytes; Middle Aged; Thymidine; Ultraviolet Rays | 1986 |
Mechanism of unbalanced growth-induced cell damage. II. A probable relationship between unbalanced growth, DNA breakage and cell death.
Topics: Animals; Cell Division; Cell Survival; DNA Damage; DNA Replication; Endodeoxyribonucleases; Hydroxyurea; Kinetics; Leukemia L5178; Mice; Thymidine | 1986 |
Modulation of cytosine arabinoside (ara-C) and high-dose ara-C in acute leukemia.
Topics: Aminoacridines; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Drug Resistance; Humans; Hydroxyurea; Interphase; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Thymidine | 1985 |
A possible secondary role for thymine-containing DNA precursors.
Topics: DNA; DNA Repair; DNA, Bacterial; DNA, Viral; Escherichia coli; Genes, Viral; Hydroxyurea; Models, Biological; Mutation; Nucleic Acid Precursors; Recombination, Genetic; T-Phages; Thymidine; Thymine | 1985 |
The utility of combinations of drugs directed at specific sites of the same target enzyme--ribonucleotide reductase as the model.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Cells, Cultured; Deoxyadenosines; Deoxyguanosine; Hydroxyurea; Isoquinolines; Leukemia L1210; Models, Biological; Nucleic Acid Synthesis Inhibitors; Phosphorylases; Pyrazoles; Ribonucleoside Diphosphate Reductase; Ribonucleotide Reductases; Thymidine; Vidarabine | 1985 |
Relations between synthesis of deoxyribonucleotides and DNA replication in 3T6 fibroblasts.
Topics: Animals; Aphidicolin; Deoxycytidine; Deoxyribonucleotides; Diterpenes; DNA Replication; Fibroblasts; Hydroxyurea; Mice; Thymidine; Thymidylate Synthase; Thymine Nucleotides | 1985 |
Evidence for the involvement of substrate cycles in the regulation of deoxyribonucleoside triphosphate pools in 3T6 cells.
Topics: Animals; Aphidicolin; Cells, Cultured; Cytidine; Cytidine Diphosphate; Deoxyribonucleotides; Diterpenes; DNA Polymerase II; DNA Replication; Hydroxyurea; Kinetics; Methotrexate; Mice; Radioisotope Dilution Technique; Thymidine; Tritium | 1985 |
Inhibition of polymerases-alpha and -beta completely blocks DNA repair induced by UV irradiation in cultured mouse neuronal cells.
Topics: Animals; Aphidicolin; Cells, Cultured; Dideoxynucleosides; Diterpenes; DNA; DNA Polymerase I; DNA Polymerase II; DNA Repair; Hydroxyurea; Mice; Mice, Inbred C57BL; Neurons; Thymidine; Ultraviolet Rays | 1985 |
On the regulation of deoxyribonucleotide synthesis.
Topics: Animals; Aphidicolin; Cell Cycle; Cells, Cultured; Cytidine; Deoxycytidine; Deoxyribonucleotides; Diterpenes; DNA Replication; Fibroblasts; Homeostasis; Hydroxyurea; Kinetics; Mice; Thymidine | 1985 |
DNA repair by articular chondrocytes. III. Unscheduled DNA synthesis following ultraviolet light irradiation of resting cartilage.
Topics: Aging; Animals; Aphidicolin; Autoradiography; Body Water; Cartilage, Articular; Cells, Cultured; Diterpenes; DNA Repair; DNA Replication; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Hydroxyurea; Kinetics; Organ Specificity; Rabbits; Thymidine; Tritium; Ultraviolet Rays | 1985 |
Does amrinone inhibition of stimulated bone resorption involve Na+-Ca++ exchange?
Topics: Aminopyridines; Amrinone; Animals; Bone Resorption; Calcium; Cardiotonic Agents; Cycloheximide; Dactinomycin; Hydroxyurea; In Vitro Techniques; Ion Exchange; Leucine; Mice; Parathyroid Hormone; Rats; Rats, Inbred Strains; Sodium; Thymidine; Uridine | 1986 |
[Conservation of bone marrow CFUc in different phases of the cell cycle during cryopreservation].
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Cycle; Freezing; Hematopoiesis; Hydroxyurea; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Stem Cells; Temperature; Thymidine | 1985 |
Mass characteristics of DNA obtained from chromosomes of a human carcinoma cell line.
Topics: Antineoplastic Agents; Benzimidazoles; Cell Fractionation; Cell Line; Chromosomes, Human; DNA Replication; DNA, Neoplasm; Humans; Hydroxyurea; Metaphase; Mitosis; Molecular Weight; Nocodazole; Thymidine; Tritium | 1985 |
Exchange of histones H1, H2A, and H2B in vivo.
Topics: Animals; Cell Line; DNA Replication; Electrophoresis, Polyacrylamide Gel; Histones; Hydroxyurea; Liver Neoplasms, Experimental; Nucleosomes; Rats; Thymidine | 1985 |
[Comparison of the accuracy of DNA copying in the course of semiconservative and repair synthesis using an analysis of the distribution of radioactive precursors].
Topics: Animals; DNA; DNA Repair; Hydrocortisone; Hydroxyurea; Liver; Male; Myocardium; Rats; Rats, Inbred Strains; Thymidine; Tritium | 1985 |
[Synchronization of the first cell cycle of human PHA-stimulated lymphocytes with hydroxyurea].
Topics: Cell Cycle; Flow Cytometry; Humans; Hydroxyurea; Interphase; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Thymidine | 1985 |
Effects of hydroxyurea and thymidine derivatives on the uptake and metabolism of deoxycytidine and arabinofuranosylcytosine in log phase and contact-inhibited human diploid fibroblasts.
Topics: Arabinofuranosylcytosine Triphosphate; Cells, Cultured; Cytarabine; Deamination; Deoxycytidine; Deoxyuracil Nucleotides; Fibroblasts; Humans; Hydroxyurea; Thymidine; Thymine Nucleotides; Tritium | 1985 |
The effects of cell cycle position on the cytotoxicity and mutagenicity of benzo(a)pyrene in cultured Chinese hamster cells.
Topics: Animals; Benzo(a)pyrene; Cell Cycle; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; DNA Replication; Dose-Response Relationship, Drug; Hydroxyurea; Mutagens; Mutation; Thioguanine; Thymidine; Tritium | 1985 |
Measurement of DNA repair synthesis induced by ultraviolet radiation.
Topics: Autoradiography; DNA; DNA Repair; Humans; Hydroxyurea; Thymidine; Tritium; Ultraviolet Rays | 1985 |
Synchronization of Leishmania tarentolae by hydroxyurea.
Topics: Agar; Aminopterin; Animals; Cell Division; Culture Media; DNA; Hydroxyurea; Leishmania; Mitochondria; Nalidixic Acid; Nucleosides; Staining and Labeling; Thymidine; Time Factors; Tritium | 1970 |
[Estimation of tumor sensitivity in vitro. II. Studies with the solid Ehrlich carcinoma of the mouse and the GW 77, a heterotransplanted human carcinoma].
Topics: Animals; Antibiotics, Antineoplastic; Autoradiography; Carcinoma; Carcinoma, Ehrlich Tumor; Colonic Neoplasms; Cricetinae; Culture Media; Cytarabine; Dactinomycin; DNA, Neoplasm; Humans; Hydroxyurea; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nucleosides; RNA, Neoplasm; Thymidine; Triaziquone; Tritium; Uridine | 1970 |
A simple, rapid technique for determination of the effects of chemotherapeutic agents on mammalian cell-cycle traverse.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Autoradiography; Bleomycin; Carbazoles; Cell Line; Cricetinae; Dactinomycin; Depression, Chemical; DNA; Hydroxyurea; In Vitro Techniques; Methods; Mitosis; Proteins; Puromycin; Threonine; Thymidine; Tritium | 1972 |
Use of flow microfluorometry in detailed analysis of effects of chemical agents on cell cycle progression.
Topics: Animals; Antineoplastic Agents; Autoradiography; Bleomycin; Camptothecin; Cell Division; Cell Line; Cricetinae; Cytarabine; DNA Replication; Fluorometry; Hydroxyurea; Mitosis; Thymidine; Time Factors; Tritium | 1972 |
Letter: Sequential G and C chromosome banding.
Topics: Animals; Cells, Cultured; Chromosomes, Human, 1-3; Chromosomes, Human, 21-22 and Y; Cricetinae; Humans; Hydroxyurea; Karyotyping; Leukocytes; Methods; Sex Chromosomes; Staining and Labeling; Thymidine | 1974 |
Effects of antineoplastic drugs on plateau-phase cultures of mammalian cells. II. Bleomycin and hydroxyurea.
Topics: Animals; Bleomycin; Cell Division; Cell Line; Clone Cells; Cricetinae; DNA; Dose-Response Relationship, Drug; Hydroxyurea; Lung; Thymidine; Time Factors; Tritium | 1974 |
Flow microfluorometric analysis of cell killing with cytotoxic drugs.
Topics: Autoanalysis; Bleomycin; Cell Division; Cell Line; Cell Survival; Cytarabine; Dactinomycin; Demecolcine; DNA, Neoplasm; Histocytochemistry; Humans; Hydroxyurea; Leukemia, Myeloid; Methods; Microscopy, Fluorescence; Mitosis; Staining and Labeling; Thymidine; Time Factors; Tritium | 1974 |
[The effect of hydroxyurea on DNA synthesis of embryonic rat cells in culture].
Topics: Animals; Autoradiography; Cattle; Cell Count; Cell Division; Cell Line; Cells, Cultured; Centrifugation, Density Gradient; Culture Media; DNA; DNA Replication; Hydroxyurea; Immune Sera; Kinetics; Ligases; Photometry; Rats; Thymidine; Tritium | 1972 |
Differential inhibition of protein synthesis in the nucleus and cytoplasm of HeLa cells in the presence of actinomycin, puromycin and hydroxyurea.
Topics: Amino Acids; Cell Nucleus; Culture Techniques; Cytoplasm; Dactinomycin; Depression, Chemical; DNA; Electrophoresis, Disc; HeLa Cells; Histones; Hydroxyurea; Lysine; Nucleoproteins; Proline; Protein Biosynthesis; Puromycin; Spectrophotometry; Thymidine; Tritium | 1969 |
Fluctuations in deoxycytidine monophosphate deaminase activity during the cell cycle in synchronous populations of HeLa cells.
Topics: Aminohydrolases; Autoradiography; Carbon Isotopes; Cell Line; Cycloheximide; Cytosine Nucleotides; Dactinomycin; Female; HeLa Cells; Humans; Hydroxyurea; Mitosis; Thymidine; Time Factors; Tritium; Uterine Cervical Neoplasms | 1969 |
[Replication of nuclear and kinetoplastic deoxyribonucleic acid in Crithidia luciliae synchronized by hydroxyurea].
Topics: Animals; Autoradiography; Cell Nucleus; DNA Replication; Hydroxyurea; Mitochondria; Thymidine; Tritium; Trypanosoma | 1969 |
An analysis of the development program in relation to RNA metabolism in the ciliate Stylonychia mytilus.
Topics: Animals; Autoradiography; Cell Division; Ciliophora; Conjugation, Genetic; Dactinomycin; Hydroxyurea; RNA; Thymidine; Tritium | 1974 |
On the increased precursor incorporation into the DNA of rat liver mitochondria irradiated in vitro.
Topics: Animals; Bromodeoxyuridine; DNA Repair; DNA, Mitochondrial; Edetic Acid; Ethidium; Hydroxyurea; In Vitro Techniques; Incubators; Kinetics; Male; Mitochondria, Liver; Protein Precursors; Radiation Effects; Rats; Thymidine; Thymine Nucleotides; Tritium | 1973 |
Vaccinia virus polypeptide synthesis: sequential appearance and stability of pre- and post-replicative polypeptides.
Topics: Animals; Autoradiography; Carbon Radioisotopes; Cell Line; Cytarabine; DNA, Viral; Electrophoresis, Polyacrylamide Gel; Haplorhini; Hydroxyurea; Kidney; Methionine; Peptide Biosynthesis; Protein Hydrolysates; Sulfur Radioisotopes; Thymidine; Time Factors; Tritium; Uridine; Vaccinia virus; Virus Replication | 1974 |
Correlation between cell enlargement and nucleic acid and protein content of HeLa cells in unbalanced growth produced by inhibitors of DNA synthesis.
Topics: Cell Division; Culture Techniques; Cytarabine; DNA, Neoplasm; Female; Floxuridine; Growth; HeLa Cells; Humans; Hydroxyurea; Mechlorethamine; Mitomycins; Neoplasm Proteins; Nitrogen Mustard Compounds; RNA, Neoplasm; Thymidine | 1967 |
Repair replication of mammalian cell DNA: effects of compounds that inhibit DNA synthesis or dark repair.
Topics: Acridines; Animals; Autoradiography; Bromodeoxyuridine; Caffeine; Centrifugation, Density Gradient; Cycloheximide; Cytosine Nucleotides; Dactinomycin; Depression; DNA; DNA Replication; Floxuridine; Gentian Violet; HeLa Cells; Humans; Hydroxyurea; Iodoacetates; L Cells; Mice; Mitosis; Radiation Effects; Thymidine; Tritium; Ultraviolet Rays | 1969 |
Modification of radiation response in synchronized HeLa cells by metabolic inhibitors: effects of inhibitors of DNA and protein synthesis.
Topics: Cyclohexanes; Cytarabine; DNA; Floxuridine; HeLa Cells; Hydroxyurea; In Vitro Techniques; Mitosis; Protein Biosynthesis; Puromycin; Pyridones; Radiation Effects; Thymidine | 1969 |
Ultraviolet-light irradiation of mouse L cells: effects on cells in the DNA synthesis phase.
Topics: Animals; Caffeine; DNA; Floxuridine; Hydroxyurea; L Cells; Mice; Mitosis; Radiation Genetics; Thymidine; Tritium; Ultraviolet Rays | 1969 |
The reversible control of animal cell differentiation by the thymidine analog, 5-bromodeoxyuridine.
Topics: Animals; Autoradiography; Bromodeoxyuridine; Cartilage; Cell Differentiation; Chick Embryo; Culture Techniques; Cytarabine; DNA; Glycosaminoglycans; Hydroxyurea; Melanins; Muscle Proteins; Muscles; Retina; RNA; Thymidine; Time Factors; Tritium | 1970 |
Failure of alkylated HEp.2 cells to replicate newly synthesized DNA.
Topics: Alkanes; Alkylating Agents; Carbon Isotopes; Carcinoma; Cell Line; Centrifugation, Density Gradient; Chemical Precipitation; Culture Media; Culture Techniques; Deoxyuridine; DNA; DNA Repair; DNA Replication; Floxuridine; Humans; Hydroxyurea; Laryngeal Neoplasms; Methods; Sulfonic Acids; Thymidine; Tritium | 1971 |
Informational DNA synthesis distinguished from that of nuclear DNA by inhibitors of DNA synthesis.
Topics: Animals; Cell Nucleus; Cells, Cultured; Chick Embryo; Cytarabine; Cytoplasm; Depression, Chemical; DNA; Floxuridine; Genetic Code; Hydroxyurea; Muscles; Thymidine; Tritium | 1971 |
Perturbations in precursor incorporation into DNA of x-irradiated HeLa S3 cells.
Topics: Autoradiography; Carbon Isotopes; Culture Techniques; Cytosine Nucleotides; DNA; DNA Replication; Floxuridine; HeLa Cells; Hydroxyurea; Kinetics; Mitosis; Radiation Effects; Thymidine; Time Factors; Tritium | 1971 |
Development of coliphage T5: ultrastructural and biochemical studies.
Topics: Bacteriolysis; Carbon Isotopes; Centrifugation, Density Gradient; Coliphages; Colorimetry; Cytidine; Cytoplasm; DNA Replication; DNA, Bacterial; DNA, Viral; Escherichia coli; Floxuridine; Hydroxyurea; Inclusion Bodies, Viral; Lysogeny; Microscopy, Electron; Mutation; Nalidixic Acid; Thymidine; Time Factors; Tritium; Viral Proteins; Virus Replication | 1972 |
[Studies on synchronisation in vivo: temporary inhibition of DNA synthesis in normal and malignant mammalian cell systems with hydroxyurea].
Topics: Animals; Autoradiography; Blood Cells; Cells, Cultured; DNA; DNA Replication; DNA, Neoplasm; Female; Half-Life; Hydroxyurea; Lymphocytes; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Models, Biological; Rats; Rats, Inbred Strains; Thymidine; Tritium | 1971 |
DNA synthesis, repair and chromosome breaks in eucaryotic cells.
Topics: Alkylating Agents; Bromodeoxyuridine; Carcinoma; Cell Line; Centrifugation, Density Gradient; Chromatids; Chromosomes; DNA; DNA Repair; DNA Replication; Floxuridine; Humans; Hydroxyurea; Laryngeal Neoplasms; Methane; Methods; Models, Biological; Sulfonic Acids; Thymidine; Tritium | 1972 |
Replicon origins in Chinese hamsters cell DNA. I. Labeling procedure and preliminary observations.
Topics: Aminopterin; Animals; Autoradiography; Cell Line; Cells, Cultured; Cricetinae; DNA Replication; Floxuridine; Hydroxyurea; Kinetics; Mitosis; Thymidine; Time Factors; Tritium | 1972 |
Induction of phosvitin by oestradiol in rooster liver needs DNA synthesis.
Topics: Animals; Bromodeoxyuridine; Chickens; Depression, Chemical; DNA; Egg Proteins; Estradiol; Floxuridine; Hydroxyurea; Kinetics; Liver; Male; Mitomycins; Phosphoproteins; Serum Albumin; Stimulation, Chemical; Thymidine; Tritium | 1972 |
DNA replication: direction and rate of chain growth in mammalian cells.
Topics: Animals; Autoradiography; Cell Line; Cycloheximide; Cytidine; DNA Replication; Fibroblasts; Floxuridine; Hydroxyurea; Mice; Puromycin; Thymidine; Time Factors; Tritium | 1973 |
DNA synthesis inhibition, cytotoxicity and their relationship to teratogenesis following administration of a nicotinamide antagonist, aminothiadiazole, to pregnant rats.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Cytarabine; Depression, Chemical; DNA; Female; Forelimb; Heart Defects, Congenital; Hydroxyurea; Niacinamide; Pregnancy; Rats; Tail; Thiadiazoles; Thymidine; Time Factors; Tritium | 1973 |
Evaluation of S phase synchronization by analysis of DNA replication in 5-bromodeoxyuridine.
Topics: Animals; Autoradiography; Bromodeoxyuridine; Carbon Radioisotopes; Cell Count; Cells, Cultured; Centrifugation, Density Gradient; Cesium; Chlorides; Cricetinae; Culture Media; DNA; DNA Replication; Female; Floxuridine; Hydroxyurea; Mitosis; Ovary; Phosphorus Radioisotopes; Thymidine; Time Factors | 1973 |
Synthesis of DNA in snail embryos during the early cleavage.
Topics: Animals; Cell Division; Cell Nucleus; DNA; Embryo, Nonmammalian; Floxuridine; Hydroxyurea; Snails; Thymidine | 1973 |
Transdifferentiation in the labial gland of silk moths: is DNA required for cellular metamorphosis?
Topics: Animals; Autoradiography; Bombyx; Cell Differentiation; DNA; Floxuridine; Histological Techniques; Hydroxyurea; Larva; Metamorphosis, Biological; Mitomycins; Physostigmine; Pupa; Salt Gland; Thymidine; Time Factors; Tritium | 1974 |
Differential effects of metabolic inhibitors on cytoplasmic membrane associated and nuclear DNA.
Topics: Antimetabolites; Benzyl Compounds; Biological Transport; Bromodeoxyuridine; Carbon Radioisotopes; Cell Division; Cell Line; Cell Membrane; Cell Nucleus; Centrifugation, Density Gradient; Cytarabine; DNA; Ethidium; Floxuridine; Humans; Hydroxyurea; Lymphocytes; Rifampin; Thymidine; Time Factors | 1974 |
Effect of specific inhibitors on mitochondrial DNA replication in HeLa cells.
Topics: Carbon Radioisotopes; Centrifugation, Density Gradient; Cytarabine; Deoxyadenosines; DNA; DNA Replication; DNA, Mitochondrial; Ethidium; Floxuridine; HeLa Cells; Hydroxyurea; Thymidine; Tritium | 1974 |
Effects of hydroxyurea on polyoma virus replication.
Topics: Animals; Culture Techniques; DNA; Fluorescent Antibody Technique; Hydroxyurea; Mice; Polyomavirus; Thymidine; Tritium; Virus Replication | 1968 |
Influence of the rate of cell growth and cell density on interferon action in chick embryo cells.
Topics: Animals; Cell Line; Chick Embryo; Culture Techniques; DNA; Edetic Acid; Hydroxyurea; Interferons; Thymidine; Tritium; Trypsin; Vesicular stomatitis Indiana virus | 1969 |
[Giant cell formation and virus-specific antigens of herpesvirus hominis: information flow from the parental DNA].
Topics: Animals; Antigens; Autoradiography; Cell Line; Cytarabine; Cytopathogenic Effect, Viral; Hydroxyurea; Kidney; Mitomycins; Rabbits; Radiation Effects; RNA; Simplexvirus; Thymidine; Tritium; Ultraviolet Rays; Uridine | 1969 |
Effects of hydroxyurea and 6-mercaptopurine on growth and some aspects of carbohydrate metabolism in regenerating and neoplastic liver.
Topics: Animals; Body Weight; Carcinoma, Hepatocellular; DNA; DNA, Neoplasm; Glucokinase; Glucose; Hepatectomy; Hexokinase; Hydroxyurea; Liver Glycogen; Liver Neoplasms; Liver Regeneration; Male; Mercaptopurine; Neoplasms, Experimental; Organ Size; Phosphofructokinase-1; Rats; Thymidine; Time Factors; Tritium | 1970 |
Newly synthesized mammalian cell DNA: studies on the reasons for the increased affinity to nitrocellulose.
Topics: Alcohols; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cellulose; Centrifugation, Density Gradient; Chloroform; Chromatography; Detergents; DNA; DNA, Neoplasm; Hydrogen-Ion Concentration; Hydroxyapatites; Hydroxyurea; Methylation; Mice; Nitro Compounds; Osmolar Concentration; Serum Albumin; Silicon Dioxide; Solubility; Sulfuric Acids; Thymidine; Tritium; Uridine | 1971 |
Unscheduled DNA synthesis, u.v.-induced chromosome aberrations and SV 40 transformation in cultured cells from xeroderma pigmentosum.
Topics: Adult; Autoradiography; Cell Transformation, Neoplastic; Cells, Cultured; Child; Chromosome Aberrations; DNA; DNA Repair; Female; Fibroblasts; Humans; Hydroxyurea; Lymphocytes; Male; Simian virus 40; Thymidine; Tritium; Ultraviolet Rays; Xeroderma Pigmentosum | 1971 |
Factors affecting acid phosphatase activity in exponential and synchronized L5178Y mouse leukemia cells.
Topics: Acid Phosphatase; Animals; Bromodeoxyuridine; Cell Fractionation; Cell Line; Cell Nucleus; Dactinomycin; Daunorubicin; DNA; Electron Transport Complex IV; Hydroxyurea; Leukemia, Experimental; Lucanthone; Mice; Microsomes; Mitochondria; Mitosis; Puromycin; RNA; Thymidine; Time Factors | 1972 |
Nuclear polyadenosine diphosphoribosylation during restricted macromolecular synthesis of HeLa cells.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Carbon Isotopes; Cell Nucleus; Chromatin; Cycloheximide; Cytarabine; Dactinomycin; Deoxyadenosines; DNA; HeLa Cells; Hydroxyurea; NAD; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Protein Biosynthesis; Ribosomes; RNA Nucleotidyltransferases; Thymidine; Tritium; Uridine; Valine | 1972 |
Sequence of spontaneous Epstein-Barr virus activation and selective DNA synthesis in activated cells in the presence of hydroxyurea.
Topics: Adenine; Antigens, Viral; Autoradiography; Bromodeoxyuridine; Carbon Isotopes; Carcinoma; Cell Line; Cells, Cultured; Centrifugation, Density Gradient; Cytarabine; DNA, Viral; Fluorescent Antibody Technique; Herpesviridae; Herpesvirus 4, Human; Humans; Hydroxyurea; Nasopharyngeal Neoplasms; Thymidine; Thymidine Kinase; Tritium; Virus Replication | 1972 |
Repair replication: a density-gradient analysis of DNA from cells infected with mengovirus or Newcastle disease virus.
Topics: Bromodeoxyuridine; Carbon Isotopes; Centrifugation, Density Gradient; DNA; DNA Repair; DNA Replication; Floxuridine; HeLa Cells; Humans; Hydroxyurea; Mengovirus; Newcastle disease virus; Puromycin; Radiation Effects; Thymidine; Tritium; Ultraviolet Rays | 1972 |
The value of hydroxyurea in assessing repair synthesis of DNA in HeLa cells.
Topics: Alkanesulfonates; Cells, Cultured; Centrifugation, Density Gradient; Chlordan; Cyclohexylamines; DDT; DNA; DNA Repair; HeLa Cells; Hydroxylamines; Hydroxyurea; Methylmercury Compounds; Thymidine; Tritium; Ultraviolet Rays | 1972 |
Hydroxyurea-induced accumulation of short fragments during polyoma DNA replication. I. Characterization of fragments.
Topics: Animals; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Culture Techniques; DNA; DNA Replication; DNA, Viral; Escherichia coli; Exonucleases; Fibroblasts; Hydroxyurea; Mice; Polyomavirus; Thymidine; Time Factors; Tritium | 1973 |
Hydroxyurea-induced accumulation of short fragments during polyoma DNA replication. II. Behavior during incubation of isolated nuclei.
Topics: Animals; Cell Nucleus; Centrifugation, Density Gradient; Chromatography, Ion Exchange; Culture Techniques; DNA Replication; DNA, Viral; Fibroblasts; Hydroxyurea; Mice; Phosphorus Radioisotopes; Polyomavirus; Thymidine; Tritium | 1973 |
DNA replication in SV40-infected cells. IX. The inhibition of a gap-filling step during discontinuous synthesis of SV40 DNA.
Topics: Animals; Cell Line; Cell-Free System; Centrifugation, Density Gradient; Coliphages; Culture Techniques; DNA Nucleotidyltransferases; DNA Repair; DNA Replication; DNA, Viral; Escherichia coli; Haplorhini; Hydroxyurea; Kidney; Models, Chemical; Nucleic Acid Hybridization; Oligonucleotides; Phosphorus Radioisotopes; Polynucleotide Ligases; Simian virus 40; Thymidine; Tritium; Virus Cultivation | 1973 |
Enancement of uptake of Simian virus 40 by nuclei of permissive cells.
Topics: Animals; Cell Nucleus; Cells, Cultured; Culture Media; Cycloheximide; Cytarabine; Cytoplasm; Dactinomycin; DNA; Floxuridine; Haplorhini; Histones; Hydroxyurea; Kidney; Kinetics; Magnesium Sulfate; RNA; Simian virus 40; Thymidine; Tritium; Uridine | 1973 |
Analysis of minimal functions of simian virus 40. 3. Evidence for "host cell repair" of oncogenicity and infectivity of UV-irradiated simian virus 40.
Topics: Animals; Autoradiography; Caffeine; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Defective Viruses; DNA; DNA Repair; Haplorhini; Hydroxyurea; Kidney; Radiation Effects; Simian virus 40; Thymidine; Time Factors; Tritium; Ultraviolet Rays; Virus Replication | 1974 |
A temperature-sensitive function in a Chinese hamster line affecting DNA synthesis.
Topics: Animals; Autoradiography; Cattle; Cell Fusion; Cell Line; Cells, Cultured; Cricetinae; Culture Media; DNA; Genes, Recessive; Hybridization, Genetic; Hydroxyurea; Immune Sera; Karyotyping; Kidney; Mitosis; Mutation; Parainfluenza Virus 1, Human; Protein Biosynthesis; Temperature; Thymidine; Time Factors; Tritium | 1973 |
The relationship between cell growth, macromolecular synthesis and poly ADP-ribose polymerase in lymphoid cells.
Topics: Adenosine Diphosphate; Animals; Cell Division; Cell Line; Cell Nucleus; Cycloheximide; Dactinomycin; DNA; Floxuridine; Hydroxyurea; Lectins; Lymphocytes; Lymphoma; Mice; Mitomycins; NAD; Nucleotidyltransferases; Phenylalanine; Polynucleotide Ligases; Polynucleotides; Protein Biosynthesis; Stimulation, Chemical; Swine; Thymidine; Tritium; Uridine | 1974 |
Synthesis of DNA-binding protein in WI-38 cells stimulated to synthesize DNA by medium replacement.
Topics: Autoradiography; Bucladesine; Carbon Radioisotopes; Cell Line; Cells, Cultured; Chromatography, Ion Exchange; Culture Media; DNA; Electrophoresis, Polyacrylamide Gel; Humans; Hydrocortisone; Hydroxyurea; Leucine; Lung; Mitosis; Molecular Weight; Protein Binding; Protein Biosynthesis; Proteins; Stereoisomerism; Thymidine; Time Factors; Tritium | 1974 |
Thymidine transport by Novikoff rat hepatoma cells synchronized by double hydroxyurea treatment.
Topics: Animals; Biological Transport, Active; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Chromatography, Paper; DNA, Neoplasm; Hydroxyurea; Liver Neoplasms; Microscopy, Phase-Contrast; Mitosis; Neoplasms, Experimental; Oxidative Phosphorylation; Rats; Thymidine; Thymine Nucleotides; Time Factors; Tritium | 1974 |
Accumulation of single-stranded regions in DNA and the block to replication in a human cell line alkylated with methyl methane sulfonate.
Topics: Alkylation; Carbon Radioisotopes; Cell Line; Centrifugation, Density Gradient; Chromatography; Chromatography, DEAE-Cellulose; Deoxyribonucleases; DNA Repair; DNA Replication; DNA, Neoplasm; DNA, Single-Stranded; Exonucleases; Humans; Hydroxyapatites; Hydroxyurea; Laryngeal Neoplasms; Mesylates; Neurospora crassa; Sucrose; Templates, Genetic; Thymidine; Tritium | 1974 |
Enhanced activation of the repressed Epstein-Barr viral genome by inhibitors of DNA synthesis.
Topics: Burkitt Lymphoma; Cell Line; Cell Transformation, Neoplastic; Cytarabine; DNA; Genotype; Herpesvirus 4, Human; Hydroxyurea; Mitosis; Thymidine; Time Factors; Virus Replication | 1974 |
Intracellular conversions of deoxyribonucleosides by Novikoff rat hepatoma cells and effects of hydroxyurea.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Cycloheximide; Cytidine; Deamination; Deoxyadenosines; Deoxyribonucleosides; Deoxyuridine; Diphosphates; Dipyridamole; DNA, Neoplasm; Guanine Nucleotides; Hydroxyurea; Hypoxanthines; Inosine; Inosine Nucleotides; Liver Neoplasms; Neoplasms, Experimental; Phosphates; Rats; RNA, Neoplasm; Thymidine; Time Factors; Tritium | 1974 |
Further studies on the development of Yaba poxvirus in cell culture.
Topics: Adsorption; Animals; Autoradiography; Cell Line; Cytoplasm; DNA, Viral; Fluorescent Antibody Technique; Haplorhini; Hydroxyurea; Kidney; Macaca; Microscopy, Electron; Models, Biological; Morphogenesis; Phagocytosis; Thymidine; Time Factors; Tritium; Viral Proteins; Virus Replication; Yaba monkey tumor virus | 1973 |
Inhibitors of DNA synthesis: their influence on replication and transcription of simian virus 40 DNA.
Topics: Animals; Cell Line; Centrifugation, Zonal; Chloroquine; Cytarabine; DNA Replication; Floxuridine; Haplorhini; Hydroxyurea; In Vitro Techniques; Kidney; Lucanthone; Mutation; Nucleic Acid Hybridization; Simian virus 40; Temperature; Thymidine; Time Factors; Transcription, Genetic; Tritium; Virus Replication | 1974 |
Further studies of histone phosphorylation in the presence of inhibitors of DNA synthesis.
Topics: Carcinoma, Hepatocellular; Cells, Cultured; Cycloheximide; DNA, Neoplasm; Enzyme Activation; Histones; Hydroxyurea; Kinetics; Liver Neoplasms; Lysine; Neoplasm Proteins; Neoplasms, Experimental; Phosphates; Phosphoric Monoester Hydrolases; Phosphorus Radioisotopes; Thymidine; Tritium | 1974 |
Programming of events in Epstein-Barr virus-activated cells induced by 5-iododeoxyuridine.
Topics: Antigens, Viral; Autoradiography; Burkitt Lymphoma; Cell Line; Cells, Cultured; Cytarabine; Deoxycytidine; DNA Replication; DNA, Neoplasm; DNA, Viral; Fluorescent Antibody Technique; Herpesvirus 4, Human; Humans; Hydroxyurea; Idoxuridine; Mitosis; Thymidine; Time Factors; Tritium; Viral Proteins; Virus Replication | 1974 |
Observations on the resistance of Fpstein-Barr virus DNA synthesis to hydroxyurea.
Topics: Antigens, Viral; Burkitt Lymphoma; Cell Line; Cytarabine; Depression, Chemical; DNA Replication; DNA, Viral; Fluorescent Antibody Technique; Herpesvirus 4, Human; Hybrid Cells; Hydroxyurea; Idoxuridine; Nucleic Acid Hybridization; Thymidine; Tritium | 1974 |
Cell kinetic studies in patients with small cell carcinoma of the lung.
Topics: Autoradiography; Biopsy; Bone Marrow; Carcinoma, Small Cell; Cell Division; Cyclohexanes; Cyclophosphamide; DNA Replication; Humans; Hydroxyurea; Lung Neoplasms; Lymph Nodes; Methotrexate; Nitrosourea Compounds; Remission, Spontaneous; Thymidine; Time Factors; Tritium | 1974 |
Replication of simian virus 40 in permissive cells: assembly of virus components.
Topics: Amino Acids; Animals; Arginine; Carbon Radioisotopes; Cell Fractionation; Cell Line; Cell Nucleus; Centrifugation, Density Gradient; Culture Media; Cycloheximide; Cytoplasm; DNA, Viral; Electrophoresis, Polyacrylamide Gel; Haplorhini; Hydroxyurea; Kidney; Nucleoproteins; Peptide Biosynthesis; Simian virus 40; Thymidine; Tritium; Viral Proteins; Virus Replication | 1974 |
Isolation of herpes simplex virus DNA from virus particles and infected cells by electrophoresis in polyacrylamide gels.
Topics: Animals; Camptothecin; Carbon Radioisotopes; Cell Fractionation; Cell Line; Cell Nucleus; Centrifugation, Density Gradient; Cytarabine; Cytoplasm; DNA; DNA Replication; DNA, Viral; Electrophoresis, Polyacrylamide Gel; Haplorhini; Hydroxyurea; Kidney; Molecular Weight; Simplexvirus; Thymidine; Tritium | 1974 |
Expression of the viral thymidine kinase gene in herpes simplex virus-transformed L cells.
Topics: Animals; Cell Division; Cell Fractionation; Cell Nucleus; Cell Transformation, Neoplastic; Cytoplasm; DNA; DNA, Neoplasm; Genes; Hydroxyurea; L Cells; Mice; Mitochondria; Mutation; Simplexvirus; Thymidine; Thymidine Kinase; Tritium | 1974 |
Regulation of N-acetylglucosamine kinase synthesis in yeast.
Topics: Acetamides; Acetates; Biological Transport; Candida albicans; Cell Division; Cycloheximide; Dactinomycin; Deoxyadenosines; DNA; Enzyme Induction; Fungal Proteins; Glucosamine; Glucose; Hydroxyurea; Lysine; Mitomycins; Phosphotransferases; Protein Biosynthesis; Thymidine; Time Factors; Tritium | 1974 |
A temperature-sensitive cell cycle mutant of the BHK cell line.
Topics: Animals; Cell Division; Cell Line; Cricetinae; Cyclic AMP; DNA; Hydroxyurea; Isoleucine; Kidney; Mitochondria; Mutation; Polyomavirus; Protein Biosynthesis; Proteins; RNA; Temperature; Thymidine; Time Factors; Tritium | 1974 |
Repair replication of opossum lymphocyte DNA: effect of compounds that bind to DNA.
Topics: Acridines; Alkylating Agents; Animals; Autoradiography; Binding Sites; Bromodeoxyuridine; Centrifugation, Density Gradient; Cycloheximide; Dactinomycin; DNA Repair; DNA Replication; Hydroxyurea; Kinetics; Lymphocytes; Mesylates; Opossums; Quinacrine; Radiation Effects; Thymidine; Tritium; Ultraviolet Rays | 1974 |
Induction of N-acetylglucosamine kinase in yeast.
Topics: Candida albicans; Cycloheximide; Dactinomycin; Enzyme Induction; Fungal Proteins; Glucosamine; Hydroxyurea; Mitomycins; Phosphotransferases; RNA; Thymidine; Time Factors; Uridine | 1974 |
Nucleic acid and protein synthesis and pattern regulation in hydra. II. Effect of inhibition of nucleic acid and protein synthesis on hypostome formation.
Topics: Animals; Chloramphenicol; Cnidaria; Cytosine; Dactinomycin; DNA; Fluorouracil; Hydroxyurea; Morphogenesis; Protein Biosynthesis; RNA; RNA, Messenger; Thymidine; Transplantation; Tritium; Uridine | 1969 |
Superinduction of tyrosine aminotransferase by actinomycin D in rat hepatoma (HTC) cells.
Topics: Animals; Antibodies; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Culture Techniques; Dactinomycin; DNA; Enzyme Induction; Hydroxyurea; Liver Neoplasms; Mitomycins; Nucleosides; Rats; RNA; Thymidine; Tyrosine Transaminase; Uridine; Vibration | 1970 |
Evidence for a -adrenergic receptor initiating DNA synthesis in haemopoietic stem cells.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Bone Marrow Cells; Cell Membrane; Cells, Cultured; Culture Media; DNA; Female; Hematopoietic Stem Cells; Hydroxyurea; Imidazoles; Isoproterenol; Methods; Mice; Mice, Inbred Strains; Propranolol; Thymidine; Time Factors; Tritium | 1972 |
Anomalous enhancing effect of hydroxyurea on DNA synthesis.
Topics: Animals; Cell Division; DNA; Dose-Response Relationship, Drug; Eukaryota; Hydroxyurea; Thymidine; Time Factors; Tritium | 1974 |
Biochemical and electron microscopic observations of vaccinia virus morphogenesis in HeLa cells after hydroxyurea reversal.
Topics: Carbon Radioisotopes; Cell Fractionation; Centrifugation, Density Gradient; Cytoplasm; DNA, Viral; HeLa Cells; Humans; Hydroxyurea; Microscopy, Electron; Morphogenesis; Nucleoproteins; Thymidine; Tritium; Vaccinia virus; Viral Proteins; Virus Replication | 1974 |
RNA-nascent DNA complexes in Ehrlich ascites tumor cells in vivo.
Topics: Animals; Carbon Radioisotopes; Carcinoma, Ehrlich Tumor; Centrifugation, Density Gradient; Chromatography, Paper; Dactinomycin; DNA Replication; DNA, Neoplasm; Hydroxyurea; Male; Mice; Neoplasm Transplantation; RNA, Neoplasm; Thymidine; Tritium; Uridine | 1974 |
DNA synthesis in multiple myeloma cells following cell cycle-nonspecific chemotherapy.
Topics: Alkylating Agents; Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Division; Cells, Cultured; Cytarabine; DNA Repair; DNA, Neoplasm; Humans; Hydroxyurea; Multiple Myeloma; Remission, Spontaneous; Thymidine; Tritium | 1974 |
Effect of early inhibition of DNA synthesis by hydroxyurea on 7,12-dimethylbenz(a)anthracene mammary carcinogenesis in the rat.
Topics: Adenoma; Animals; Autoradiography; Benz(a)Anthracenes; Carcinoma; Depression, Chemical; DNA; Epithelial Cells; Epithelium; Female; Hydroxyurea; Mammary Neoplasms, Experimental; Progesterone; Rats; Thymidine; Time Factors; Tritium | 1974 |
Inhibition of glycoprotein and glycolipid synthesis in hamster embryo cells by cytosine arabinoside and hydroxyurea.
Topics: Animals; Carbon Radioisotopes; Cell Membrane; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Cytarabine; DNA; DNA Replication; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Glucosamine; Glycolipids; Glycoproteins; Hydroxyurea; Thymidine; Tritium | 1974 |
Altered ribonucleotide reductase activity in mammalian tissue culture cells resistant to hydroxyurea.
Topics: Animals; Binding Sites; Cell Line; Cells, Cultured; Cricetinae; Culture Media; Diamines; Dose-Response Relationship, Drug; Drug Resistance; Female; Genes; Hydroxyurea; L Cells; Mice; Ovary; Ribonucleotide Reductases; Thymidine; Time Factors; Triazoles; Tritium | 1974 |
Different action of suicidal doses of tritiated thymidine and hydroxyurea on murine haemopoietic cells.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Division; Cell Survival; Cells, Cultured; Deoxyuridine; DNA; Dose-Response Relationship, Drug; Female; Femur; Hydroxyurea; Idoxuridine; Iodine Radioisotopes; Kinetics; Mice; Mice, Inbred CBA; Spleen; Thymidine; Time Factors; Tritium | 1974 |
Stalk formation and its inhibition in Caulobacter crescentus.
Topics: Adenosine Triphosphate; Bacteria; Bacterial Proteins; Carbon Radioisotopes; Cell Division; DNA, Bacterial; Hydroxyurea; Leucine; Mitomycins; Morphogenesis; Mutation; Phosphates; RNA, Bacterial; Thymidine; Tritium; Uridine | 1974 |
DNA metabolism during pachytene in relation to crossing over.
Topics: Centrifugation, Density Gradient; Chromatin; Crossing Over, Genetic; DNA; DNA Repair; Hydroxyurea; Meiosis; Organoids; Plants; Thymidine; Tritium; Uracil | 1974 |
A simple and rapid method for assaying cytotoxicity.
Topics: Cells, Cultured; DNA; Fibroblasts; Hydroxyurea; Rose Bengal; Sodium Dodecyl Sulfate; Thymidine; Time Factors; Tritium; Trypsin | 1974 |
The synthesis and degradation of RNA containing polyriboadenylate during sea urchin embryogeny.
Topics: Adenine Nucleotides; Adenosine; Animals; Carbon Radioisotopes; Cell Fractionation; Cell Nucleus; Centrifugation, Density Gradient; Chromatography; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Formaldehyde; Hydroxyurea; Kinetics; Mitosis; Oligonucleotides; Polynucleotides; Ribonucleases; RNA; Sea Urchins; Spectrophotometry; Thymidine; Thymine Nucleotides; Tritium | 1974 |
Regulation of thymidine kinase synthesis in human cells.
Topics: Carbon Radioisotopes; Carcinoma; Cell Division; Cell Line; Cell-Free System; Cycloheximide; Dactinomycin; DNA Replication; DNA, Neoplasm; Humans; Hydroxyurea; Mitosis; Models, Biological; Mouth Neoplasms; Neoplasm Proteins; Periodicity; RNA, Neoplasm; Thymidine; Thymidine Kinase; Time Factors; Transcription, Genetic; Tritium; Valine | 1974 |
Studies on nascent DNA in mouse myeloma.
Topics: Animals; Aspergillus; Carbon Radioisotopes; Cell Line; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Clone Cells; Deoxyribonucleotides; DNA, Neoplasm; Endonucleases; Hot Temperature; Hydroxyurea; Mice; Nucleic Acid Denaturation; Plasmacytoma; RNA, Neoplasm; Thymidine; Tritium; Uridine | 1974 |
Selective enhancement of cytoplasmic protein species and continued histone synthesis during inhibition of DNA synthesis in temperature-sensitive Chinese hamster cells.
Topics: Animals; Carbon Radioisotopes; Cell Fractionation; Cell Line; Chromosomes; Cricetinae; Cytoplasm; DNA; DNA Replication; Electrophoresis, Polyacrylamide Gel; Histones; Hydroxyurea; Lysine; Nucleoproteins; Peptides; Proteins; Temperature; Thymidine; Tritium | 1974 |
Nuclear and cytoplasmic pools of deoxyribonucleoside triphosphates in Chinese hamster ovary cells.
Topics: Adenine Nucleotides; Animals; Cell Division; Cell Line; Cell Nucleus; Cricetinae; Cytoplasm; Cytosine Nucleotides; Deoxyribonucleotides; DNA; Female; Freeze Drying; Guanine Nucleotides; Hydroxyurea; Isoleucine; Mitosis; Ovary; RNA; Thymidine; Thymine Nucleotides; Time Factors; Ultrasonics | 1974 |
A sensitive method to measure physical and chemical carcinogen-induced "unscheduled DNA synthesis" in rapidly dividing eukaryotic cells.
Topics: Amnion; Animals; Arginine; Autoradiography; Carcinogens; Cattle; Cell Division; Cell Line; Cell Nucleus; Culture Media; Culture Techniques; DNA; DNA Repair; Fluorenes; Humans; Hydroxyurea; Methods; Radiation Effects; Thymidine; Tritium; Ultraviolet Rays | 1974 |
DNA repair in Potorous tridactylus.
Topics: Animals; Bromodeoxyuridine; Carbon Radioisotopes; Cell Line; Centrifugation, Density Gradient; DNA; DNA Repair; DNA Replication; Endonucleases; Humans; Hydrogen-Ion Concentration; Hydroxyurea; Isotope Labeling; Kidney; Light; Marsupialia; Phosphorus Radioisotopes; Radiation Effects; Skin; Thymidine; Time Factors; Tritium; Ultraviolet Rays; Xeroderma Pigmentosum | 1974 |
The metabolism of histone fractions. Phosphorylation and synthesis of histones in late G1-arrest.
Topics: Animals; Cell Division; Cell Line; Cricetinae; DNA; Female; Histones; Hydroxyurea; Lysine; Mitosis; Ovary; Phosphoproteins; Protein Biosynthesis; Thymidine; Time Factors; Transcription, Genetic | 1974 |
[Effect of metiazinic acid, ketoprofen, oxyphenbutazone, and flufenamic acid on the enzymes of DNA synthesis and repair in the in vitro experiment].
Topics: Acetates; Animals; Anti-Inflammatory Agents; Benzophenones; Cobalt Radioisotopes; DNA; DNA Repair; Flufenamic Acid; Gamma Rays; Humans; Hydroxyurea; In Vitro Techniques; Lymphocytes; Mice; Oxyphenbutazone; Phenothiazines; Propionates; Radiation Effects; Rats; Spleen; Thymidine | 1974 |
Selective toxicity of rifamycin derivatives for leukaemic human leucocytes.
Topics: Antibiotics, Antineoplastic; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cell Differentiation; Cells, Cultured; DNA Nucleotidyltransferases; DNA, Neoplasm; Humans; Hydroxyurea; Kinetics; Leukemia; Leukocytes; Lymphocytes; Mercaptopurine; Methotrexate; Rifampin; RNA, Neoplasm; Thymidine; Tritium; Uridine | 1972 |
DNA synthesis during maturation of starfish oocytes.
Topics: Adenosine; Animals; Centrifugation, Density Gradient; Depression, Chemical; DNA; DNA Replication; Female; Hydroxyurea; Meiosis; Ovum; Starfish; Thymidine; Tritium | 1972 |
A restriction point for control of normal animal cell proliferation.
Topics: Animals; Autoradiography; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Colchicine; Cricetinae; Culture Media; DNA; DNA Replication; Glutamine; Hydroxyurea; Isoleucine; Kidney; Kinetics; Mitosis; Thymidine; Tritium | 1974 |
True or apparent inhibition of nucleic acid synthesis by the chromosome-breaking purine derivatives adenine and 8-ethoxycaffeine.
Topics: Adenine; Caffeine; Deoxyadenosines; DNA; Hydroxyurea; Phosphates; Phosphorus Isotopes; Plants; RNA; Thymidine; Tritium | 1972 |
An anomalous effect of hydroxyurea and visible light on nucleic acids of a photoreactivating mammalian cell Potorous tridactylis.
Topics: Animals; Carbon Isotopes; Cells, Cultured; Deoxyribonucleosides; Depression, Chemical; DNA; Fluorouracil; Hydroxyurea; In Vitro Techniques; L Cells; Light; Marsupialia; Radiation Effects; Radiobiology; RNA; Thymidine; Tritium; Uridine | 1972 |
Specific increase in pyrimidine deoxynucleoside transport at the time of deoxyribonucleic acid synthesis in 3T3 mouse cells.
Topics: Animals; Biological Transport; Cell Line; Culture Media; Cycloheximide; Cytarabine; Dactinomycin; Deoxyadenosines; Deoxycytidine; Deoxyribonucleosides; DNA; Electrophoresis, Paper; Fibroblasts; Guanosine; Hydroxyurea; Kinetics; Mice; Mitomycins; Mutation; Phosphates; Phosphorus Isotopes; Thymidine; Thymidine Kinase; Time Factors; Tritium | 1973 |
Effects of cordycepin, hydroxyurea and cycloheximide on histone mRNA synthesis in synchronized HeLa cells.
Topics: Carbon Radioisotopes; Cell-Free System; Cycloheximide; Deoxyadenosines; HeLa Cells; Histones; Humans; Hydroxyurea; In Vitro Techniques; Polyribosomes; Reticulocytes; RNA, Messenger; Thymidine | 1974 |
Defective concatemer formation in cells infected with deoxyribonucleic acid-delay mutants of bacteriophage T4.
Topics: Carbon Isotopes; Centrifugation, Density Gradient; Chloramphenicol; Coliphages; DNA Replication; DNA, Single-Stranded; DNA, Viral; Escherichia coli; Hydroxyurea; Mutation; Thymidine; Time Factors; Tritium | 1972 |
Degradation of Escherichia coli chromosome after infection by bacteriophage T4: role of bacteriophage gene D2a.
Topics: Chromosomes, Bacterial; Coliphages; Deoxyribonucleases; DNA, Bacterial; Drug Resistance, Microbial; Endonucleases; Escherichia coli; Genes; Genetics, Microbial; Hydroxyurea; Lysogeny; Mutation; Nucleic Acid Denaturation; Thymidine; Tritium; Virus Replication | 1972 |
Mechanism of inhibition of deoxyribonucleic acid synthesis in Escherichia coli by hydroxyurea.
Topics: Bacterial Proteins; Carbon Isotopes; Cell Survival; Cell-Free System; Centrifugation, Density Gradient; Chromatography; Cytosine Nucleotides; Deoxyribonucleotides; DNA Repair; DNA Replication; DNA, Bacterial; Escherichia coli; Hydroxyurea; Nucleotides; Oxidoreductases; Pyrimidine Nucleotides; Ribonucleotides; RNA, Bacterial; Thymidine; Toluene; Tritium; Uracil | 1972 |
Mutants of bacteriophage T4 which allow amber mutants of gene 32 to grow in ochre-suppressing hosts.
Topics: Chromosome Mapping; Coliphages; DNA Replication; DNA Viruses; DNA, Viral; Escherichia coli; Genes; Genetic Variation; Hydroxyurea; Mutation; Phenotype; Thymidine; Tritium; Viral Proteins; Virus Replication | 1973 |
Hydroxyurea-sensitive mutants of T4. II. Degradation and utilization of bacterial DNA.
Topics: Carbon Radioisotopes; Coliphages; Crosses, Genetic; Deoxyribonucleotides; DNA, Bacterial; DNA, Viral; Drug Resistance, Microbial; Endonucleases; Escherichia coli; Genes; Genetic Complementation Test; Hydroxyurea; Molecular Weight; Mutation; Nucleic Acid Denaturation; Thymidine; Tritium | 1973 |
Single-strand breaks in deoxyribonucleic acid and viability loss during deoxyribonucleic acid synthesis inhibition in Escherichia coli.
Topics: Adenine; Carbon Radioisotopes; Cell Survival; Chromosomes, Bacterial; DNA, Bacterial; DNA, Single-Stranded; Escherichia coli; Hydroxyurea; Molecular Weight; Mutation; Nalidixic Acid; Nucleic Acid Denaturation; Temperature; Thymidine; Tritium | 1973 |
Mutation to overproduction of bacteriophage T4 gene products.
Topics: Amino Acids; Autoradiography; Carbon Radioisotopes; Cell-Free System; Coliphages; Crosses, Genetic; DNA Replication; DNA, Viral; Drug Resistance, Microbial; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Genes; Hydroxyurea; Mutation; Rifampin; RNA, Messenger; RNA, Viral; Thymidine; Time Factors; Tritium; Uridine; Viral Proteins | 1974 |
Immunoreactivity to antinucleoside antibodies in x-irradiated HeLa cells.
Topics: Antibodies; Antigen-Antibody Reactions; Cell Nucleus; Cytarabine; Dactinomycin; DNA, Neoplasm; DNA, Single-Stranded; Dose-Response Relationship, Radiation; Fluorescent Antibody Technique; HeLa Cells; Humans; Hydroxyurea; Immunologic Techniques; Mitosis; Nucleic Acid Denaturation; Nucleosides; Peroxidases; Radiation Effects; Thymidine; Time Factors; Tritium | 1974 |
Maturation of mitogen-activated bone marrow-derived lymphocytes in the absence of proliferation.
Topics: Animals; Antibody Formation; B-Lymphocytes; Cell Membrane; Cytarabine; DNA; Escherichia coli; Hemolytic Plaque Technique; Hydroxyurea; Immunoglobulin M; Lipopolysaccharides; Lymphocyte Activation; Lymphocytes; Mice; Mitogens; Polysaccharides, Bacterial; Thymidine; Tritium | 1974 |
Cytochemical and biochemical studies on progesterone-induced maturation in amphibian oocytes. 2. DNA synthesis.
Topics: Animals; Autoradiography; Benzyl Compounds; Bromodeoxyuridine; Cell Nucleus; Cytarabine; Cytological Techniques; Cytoplasm; Deoxyadenosines; DNA; DNA, Mitochondrial; Ethidium; Female; Hydroxyurea; Kinetics; Nucleic Acid Denaturation; Nucleic Acid Renaturation; Ovum; Photometry; Progesterone; Radiation Effects; Rana pipiens; Ribosomes; Rifampin; Thymidine; Xenopus | 1974 |
Regulation of DNA synthesis and cell division in starved-refed synchronized Tetrahymena pyriformis HSM.
Topics: Animals; Autoradiography; Cycloheximide; Dactinomycin; DNA; DNA Nucleotidyltransferases; DNA Replication; Fasting; Hydroxyurea; Mitosis; Proteins; RNA; Tetrahymena; Tetrahymena pyriformis; Thymidine; Time Factors; Tritium; Uridine | 1972 |
Excision repair (dimer excision, strand breakage and repair replication) in primary cultures of eukaryotic (bovine) cells.
Topics: Animals; Autoradiography; Bromodeoxyuridine; Cattle; Cell Survival; Cells, Cultured; Centrifugation, Density Gradient; Chloroquine; Chromatography, Paper; DNA; DNA Repair; DNA, Single-Stranded; Edetic Acid; Fibroblasts; Hydrogen-Ion Concentration; Hydroxyurea; Molecular Weight; Pyrimidines; Radiation Effects; Thymidine; Time Factors; Tritium; Ultraviolet Rays | 1972 |
Evidence that the synchronized production of new basal bodies is not associated with DNA synthesis in Stentor coeruleus.
Topics: Animals; Autoradiography; Cilia; Ciliophora; Cytarabine; Dactinomycin; DNA; Hydroxyurea; Mitochondria; Mitomycins; Organoids; Protein Biosynthesis; Regeneration; RNA; Thymidine; Tritium | 1972 |
[Use of an agar culture medium for experiments on tritiated thymidine incorporation into chicken embryonal gonads].
Topics: Animals; Autoradiography; Chick Embryo; Culture Media; DNA; Gonads; Hydroxyurea; Thymidine; Trichloroacetic Acid; Tritium | 1972 |
Action of hydroxyurea and N-carbamoyloxyurea on the cell cycle of Tetrahymena.
Topics: Animals; Autoradiography; Cell Division; Cell Survival; DNA; Hydroxyurea; Tetrahymena pyriformis; Thymidine; Tritium; Urea | 1973 |
Short-term inhibition of macromolecular synthesis and androgen-induced sexual differentiation of the rat brain.
Topics: Animals; Bromodeoxyuridine; Carbon Isotopes; Cycloheximide; Cytidine; Dactinomycin; DNA; Female; Gonadotropins, Pituitary; Hydroxyurea; Hypothalamo-Hypophyseal System; Hypothalamus; Leucine; Nerve Tissue Proteins; Pituitary Gland; Puromycin; Rats; RNA; Testosterone; Thymidine; Time Factors; Tritium | 1972 |
Inhibition of DNA repair replication by DNA binding drugs which sensitize cells to alkylating agents and X-rays.
Topics: Alkylating Agents; Caffeine; Chloroquine; Cyanides; Cyclophosphamide; Dinitrophenols; DNA Repair; DNA Replication; Dose-Response Relationship, Radiation; Drug Combinations; Humans; Hydroxyurea; Injections, Intraperitoneal; Leukocyte Count; Lymphocytes; Protein Binding; Quinacrine; Quinolines; Radiation Effects; Radiation-Sensitizing Agents; Thymidine; Tritium; Ultraviolet Rays | 1972 |
Cell kinetics in diffusion chambers: survival, resumption of proliferation, and maturation rate of murine haemopoietic cells.
Topics: Animals; Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Cell Division; Cell Survival; Diffusion; DNA; Female; Hydroxyurea; Leukocytes; Macrophages; Mice; Micropore Filters; Thymidine; Time Factors; Tritium; Vinblastine | 1972 |
DNA repair following exposure of human lymphocytes to 4-nitroquinoline-1-oxide.
Topics: Bromodeoxyuridine; Carcinogens; Centrifugation, Density Gradient; Culture Media; DNA; DNA Repair; DNA Replication; Humans; Hydroxyurea; Lectins; Lymphocyte Activation; Lymphocytes; Methods; Quinolines; Radiation Effects; Radioimmunoassay; Stimulation, Chemical; Thymidine; Time Factors; Tritium; Ultraviolet Rays | 1972 |
Preparation of large quantities of synchronized mammalian cells in late G1 in the pre-DNA replicative phase of the cell cycle.
Topics: Acridines; Animals; Autoradiography; Cell Line; Cells, Cultured; Cricetinae; Culture Media; Cytarabine; DNA Replication; Female; Fluorometry; Hydroxyurea; Isoleucine; Mitosis; Ovary; Thymidine; Time Factors; Tritium | 1972 |
Quantitative studies of antigen expression in cultured murine lymphoma cells. II. Cell-surface antigens in synchronized cultures.
Topics: Absorption; Animals; Antibody Specificity; Antigen-Antibody Reactions; Antigens, Neoplasm; Antigens, Viral; Blood Group Antigens; Cell Count; Cell Division; Cell Membrane; Chromium Isotopes; Hydroxyurea; Immune Sera; Lymphoma; Mice; Mice, Inbred A; Moloney murine leukemia virus; Neoplasms, Experimental; Rabbits; Thymidine; Time Factors; Tritium | 1972 |
Antineoplastic drug activity in the mitotic cycle--effects of six agents on macromolecular synthesis in synchronous mammalian leukemic cells.
Topics: Animals; Antineoplastic Agents; Asparaginase; Azaserine; Camptothecin; Culture Media; DNA, Neoplasm; Ethidium; Fucose; Glucosamine; Glycoproteins; Hydroxyurea; Leucine; Leukemia, Experimental; Mice; Mitosis; Neoplasm Proteins; RNA, Neoplasm; Thymidine; Time Factors; Tritium; Uridine | 1972 |
Influence of drugs and synchrony on the hyperthermic killing of HeLa cells.
Topics: Cell Division; Cell Survival; Cycloheximide; HeLa Cells; Hot Temperature; Humans; Hydroxyurea; Leucine; Thymidine; Tritium; Uridine | 1973 |
Effect of endotoxin on granulopoiesis and the in vitro colony-forming cell.
Topics: Animals; Autoradiography; Cell Division; Clone Cells; DNA; Endotoxins; Female; Hematopoiesis; Hematopoietic Stem Cells; Hydroxyurea; Leukocyte Count; Leukocytes; Mice; Neutrophils; Salmonella typhi; Thymidine; Tritium | 1973 |
Requirement for cell proliferation for the effects of 5-bromo-2'-deoxyuridine on cultures of chick chondrocytes.
Topics: Animals; Bromodeoxyuridine; Cartilage; Cell Division; Cells, Cultured; Chick Embryo; Chondroitin; Culture Media; Cycloheximide; Cytarabine; DNA; DNA Replication; Glucosamine; Hydroxyurea; Leucine; Sulfates; Sulfur Isotopes; Thymidine; Tritium | 1973 |
[Cytokinetic studies on the proliferating activity of mast cells in the regnerating bone marrow of the rat].
Topics: Age Factors; Animals; Bone Marrow; Bone Marrow Cells; Bone Marrow Diseases; Cell Division; Cell Movement; DNA; Female; Hematopoiesis; Hydroxyurea; Mast Cells; Rats; Regeneration; Thymidine; Time Factors; Tritium | 1973 |
The effect of dose interval on the survival of L1210 leukemic mice treated with DNA synthesis inhibitors.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Division; Cell Survival; Cytarabine; DNA, Neoplasm; Formates; Hydroxyurea; Leukemia L1210; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Pyridines; Thiosemicarbazones; Thymidine; Time Factors | 1973 |
Kinetic parameters of bone marrow stem cells using in vivo suicide by tritiated thymidine or by hydroxyurea.
Topics: Animals; Cell Division; Cell Survival; Hematopoietic Stem Cells; Hydroxyurea; Kinetics; Methods; Mice; Mice, Inbred C57BL; Mitosis; Thymidine; Tritium | 1973 |
Studies on the mechanism of replication of adenovirus DNA. I. The effect of hydroxyurea.
Topics: Adenoviridae; Carcinoma; Cell Line; Centrifugation, Density Gradient; Chromatography; DNA Replication; DNA, Neoplasm; DNA, Single-Stranded; DNA, Viral; Humans; Hydroxyapatites; Hydroxyurea; Mouth Neoplasms; Nucleic Acid Hybridization; Phosphorus Isotopes; Thymidine; Time Factors; Tritium | 1973 |
Mechanism of intestinal radiosensitization by actinomycin D.
Topics: Animals; Cell Division; Dactinomycin; Deoxyuridine; DNA; Hydroxyurea; Iodine Isotopes; Jejunum; Male; Mice; Radiation Effects; Radiation-Sensitizing Agents; Thymidine; Tritium | 1973 |
Effect of inhibiting the cellular synthesis of RNA, DNA and protein on DNA replicative activity of isolated S-phase nuclei.
Topics: Benzimidazoles; Cell Division; Cycloheximide; Dactinomycin; DNA Replication; DNA, Neoplasm; HeLa Cells; Humans; Hydroxyurea; Leucine; Neoplasm Proteins; Pyridines; RNA, Neoplasm; Sulfhydryl Compounds; Thymidine; Thymine Nucleotides; Time Factors; Tritium | 1973 |
Sulfhydryl groups during the S phase: comparison of cells from G 1 , plateau-phase G 1 , and G 0 .
Topics: Animals; Cell Division; Cell Line; Cricetinae; Culture Media; Cycloheximide; Dactinomycin; DNA; Female; Glutathione Reductase; Hydroxyurea; Isoleucine; Isoproterenol; Mice; Ovary; Salivary Glands; Stimulation, Chemical; Sulfhydryl Compounds; Thymidine; Time Factors; Tritium | 1973 |
DNA replication and the nuclear membrane.
Topics: Animals; Autoradiography; Cell Count; Cell Division; Cell Membrane; Cell Nucleus; Cells, Cultured; Cricetinae; DNA; DNA Replication; Female; Fibroblasts; Hydroxyurea; Isotope Labeling; Methotrexate; Microscopy, Electron; Mitosis; Rodentia; Thymidine; Time Factors; Tritium | 1973 |
Differential sensitivity of monolayer cells compared with suspension cell cultures to treatment with high concentrations of croton oil factor (TPA) and the surfactants tween 80 and triton X-100.
Topics: Cell Count; Cells, Cultured; Croton Oil; HeLa Cells; Humans; Hydroxyurea; L Cells; Sodium Dodecyl Sulfate; Surface-Active Agents; Thymidine; Tritium | 1973 |
[Generation cycle of HeLa Zh-63 cells in synchronized culture. 3. Effect of preliminary synchronization with hydroxyurea and excess of thymidine].
Topics: HeLa Cells; Hydroxyurea; Mitosis; Thymidine | 1973 |
Further observations on the late labelling associated with stimulus-responsive cells in skin.
Topics: Animals; Autoradiography; Cell Division; DNA; Hydroxyurea; Injections, Intraperitoneal; Iodine Radioisotopes; Male; Methylation; Mice; Mice, Inbred DBA; Physical Stimulation; Skin; Thymidine; Time Factors; Tritium; Uridine | 1973 |
Biosynthesis of deoxyribonucleic acid, ribonucleic acid and protein in vivo by neonatal mice after a toxic dose of cyclophosphamide.
Topics: Animals; Animals, Newborn; Body Weight; Brain; Carbon Radioisotopes; Cyclophosphamide; DNA; Hydroxyurea; Leucine; Liver; Mice; Organ Size; Protein Biosynthesis; RNA; Thymidine; Time Factors; Uridine | 1973 |
Age cohort variation of tumor cells.
Topics: Animals; Cell Division; Disease Models, Animal; DNA, Neoplasm; Fluorouracil; Hydroxyurea; Lymphoma; Mice; Mitosis; Models, Biological; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; RNA, Neoplasm; Thymidine; Time Factors; Tritium | 1973 |
Time course and localization of DNA synthesis during wound healing of potato tuber tissue.
Topics: Autoradiography; Cell Division; DNA; Hydroxyurea; Oxygen Consumption; Plant Physiological Phenomena; Plant Proteins; Plants; Regeneration; Thymidine; Time Factors; Tritium | 1973 |
The effect of inhibition of deoxyribonucleic acid synthesis on histone phosphorylation.
Topics: Amino Acids; Cells, Cultured; Cycloheximide; DNA; Dose-Response Relationship, Drug; Electrophoresis; Half-Life; Histones; Hydroxyurea; Lysine; Phosphates; Phosphorus Radioisotopes; Protein Biosynthesis; RNA; Thymidine; Time Factors; Tritium; Uridine | 1973 |
[On the mechanism of changes in blood leukocyte levels during the arousal of a hibernator: the garden dormouse (Eliomys quercinus L.)].
Topics: Animals; Cell Division; Eosinophils; Hibernation; Hydroxyurea; Injections, Intraperitoneal; Leukocyte Count; Leukocytes; Lymphocytes; Monocytes; Neutrophils; Rodentia; Thymidine; Tritium | 1973 |
[Repair synthesis of DNA in normal and leukemic lymphocytes damaged by an alkylating agent. Inhibition of repair synthesis by caffeine. Preliminary report].
Topics: Alkylating Agents; Caffeine; Cells, Cultured; DNA; DNA Repair; Humans; Hydroxyurea; Leukemia; Lymphocytes; Nitrogen Mustard Compounds; Thymidine; Tritium | 1974 |
Stimulated lymphocyte cultures: responder recruitment and cell cycle kinetics.
Topics: Animals; Cell Division; Cells, Cultured; Colchicine; Depression, Chemical; DNA; Dogs; Hydroxyurea; Kinetics; Lectins; Lymphocyte Activation; Lymphocytes; Mitosis; Thymidine; Tritium | 1974 |
Inhibition of cellular DNA synthesis in cells infected with infectious pancreatic necrosis virus.
Topics: Animals; Autoradiography; Cell Division; Cell Line; Centrifugation, Zonal; DNA; Gonads; Hydroxyurea; In Vitro Techniques; Radiation Effects; Reoviridae; Salmonidae; Thymidine; Time Factors; Tritium; Ultraviolet Rays; Viral Interference; Virus Replication | 1974 |
Androgen-induced sexual differentiation of the brain is blocked by inhibitors of DNA and RNA synthesis.
Topics: Animals; Animals, Newborn; Brain; Dactinomycin; Depression, Chemical; DNA; Estrus; Female; Fluorouracil; Gonadotropins; Hydroxyurea; Hypothalamus; Mycotoxins; Organ Size; Ovary; Ovulation; Pregnancy; Protein Biosynthesis; Puromycin; Rats; RNA; Sex Factors; Testosterone; Thymidine; Tritium | 1974 |
Stimulation of DNA synthesis by prolactin in rabbit mammary tissue.
Topics: Animals; Autoradiography; Chromatography; Culture Techniques; DNA; Female; Hydroxyurea; Lactation; Mammary Glands, Animal; Pregnancy; Prolactin; Pseudopregnancy; Rabbits; Stimulation, Chemical; Thymidine; Tritium | 1974 |
Studies with hydroxyurea. VI. Effects of hydroxyurea on the metabolism of sensitive and resistant strains of Escherichia coli.
Topics: Carbamates; Depression, Chemical; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Folic Acid; Genetics, Microbial; Hydroxyurea; Models, Biological; Nucleosides; Oxidation-Reduction; Thioctic Acid; Thymidine; Tritium; Urea; Urethane; Vitamin B 12 | 1967 |
Effect of nalidixic acid and hydroxyurea on division ability of Escherichia coli fil+ and lon- strains.
Topics: Bacterial Proteins; Carbon Isotopes; Cell Division; DNA Replication; DNA, Bacterial; Escherichia coli; Hydroxyurea; Lactones; Nalidixic Acid; RNA, Bacterial; Thymidine; Tritium; Uracil | 1968 |
Radiation stimulated incorporation of thymidine into the DNA of human lymphocytes.
Topics: Autoradiography; Culture Techniques; DNA; Humans; Hydroxyurea; Lymphocytes; Microscopy, Phase-Contrast; Radiation Effects; Thymidine; Tritium; Ultraviolet Rays | 1968 |
Studies with hydroxyurea. 8. The deoxyribonucleic acid of hydroxyurea-treated cells.
Topics: Animals; Carbon Isotopes; Cell-Free System; Chick Embryo; Chromatography, Ion Exchange; DNA Nucleotidyltransferases; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Hydroxyurea; Thymidine; Time Factors; Tritium; Ultracentrifugation | 1968 |
Biologic effects of isohydroxyurea.
Topics: Animals; Azides; Bacterial Proteins; Cricetinae; Culture Media; Culture Techniques; Depression, Chemical; DNA, Bacterial; Drug Resistance, Microbial; Escherichia coli; Hydroxyurea; Kidney; Lysine; RNA, Bacterial; Thymidine; Time Factors; Tritium; Uridine | 1969 |
Effect of hydroxyurea on replication of bacteriophage T4 in Escherichia coli.
Topics: Carbon Isotopes; Coliphages; DNA, Bacterial; DNA, Viral; Escherichia coli; Hydroxyurea; Nucleotides; Thymidine; Uracil; Virus Replication | 1969 |
Some biological effects of carbamoyloxyurea, an oxidation product of hydroxyurea.
Topics: Anti-Bacterial Agents; Azides; Bacterial Proteins; Carbon Isotopes; Chloramphenicol; DNA, Bacterial; Escherichia coli; Genetics, Microbial; Hydroxyurea; Lysine; Mutation; RNA, Bacterial; Sodium; Thymidine; Tritium; Uracil; Uridine | 1970 |
Isolation of bacteriophage T4 mutants defective in the ability to degrade host deoxyribonucleic acid.
Topics: Carbon Isotopes; Centrifugation, Density Gradient; Cesium; Chlorides; Chromatography, DEAE-Cellulose; Chromosome Mapping; Coliphages; DNA, Bacterial; DNA, Viral; Escherichia coli; Genetics, Microbial; Hydroxylamines; Hydroxyurea; Molecular Weight; Mutation; Nucleotidyltransferases; Sucrose; Thymidine; Virus Replication | 1970 |
Hydroxyurea-induced inhibition of DNA puff development in the salivary gland chromosomes of Bradysia hygida.
Topics: Animals; Autoradiography; Carbon Isotopes; Chromosomes; Diptera; DNA; Hydroxyurea; Larva; Leucine; Microscopy, Phase-Contrast; Molecular Biology; Radiometry; RNA; Salivary Glands; Spectrum Analysis; Thymidine; Tritium; Uridine | 1971 |
Biogenesis of poxviruses: role of A-type inclusions and host cell membranes in virus dissemination.
Topics: Animals; Autoradiography; Cell Membrane; Chick Embryo; Chickens; Culture Techniques; Cytarabine; Cytoplasm; Dactinomycin; DNA, Viral; Erythrocytes; Fluorescent Antibody Technique; Genetic Complementation Test; Genetics, Microbial; Goats; Golgi Apparatus; HeLa Cells; Hemadsorption; Hemagglutinins, Viral; Humans; Hydroxyurea; Immune Sera; Inclusion Bodies, Viral; L Cells; Microscopy, Electron; Organelle Biogenesis; Puromycin; Rabbits; Ribosomes; Rifampin; RNA, Viral; Species Specificity; Thymidine; Time Factors; Tritium; Vaccinia virus; Viral Proteins | 1971 |
Studies with hydroxyurea. VII. Hydroxyurea and the synthesis of functional proteins.
Topics: Alkaline Phosphatase; Bacterial Proteins; Carbon Isotopes; Chloramphenicol; DNA, Bacterial; Electrophoresis; Escherichia coli; Hydroxyurea; Immunodiffusion; Lysine; Precipitin Tests; RNA, Bacterial; RNA, Messenger; Thymidine; Transformation, Genetic; Tritium; Uracil; Uridine | 1967 |
The effect of growth inhibitors on postembryonic development in the free-living nematode, Pangrellus silusiae.
Topics: Animals; Anti-Bacterial Agents; Chloramphenicol; Cycloheximide; Dactinomycin; Depression, Chemical; DNA; Enzyme Inhibitors; Ethanol; Hydroxyurea; Leucine; Metabolism; Nalidixic Acid; Nematoda; Nucleic Acids; Protein Biosynthesis; Puromycin; RNA; Thymidine; Time Factors; Tritium; Uridine | 1970 |
[Study of the effects of hydroxyurea: cytological analysis and cytophotometric determination of deoxyribonucleic acids of chicken fibroblasts cultivated in vitro].
Topics: Animals; Autoradiography; Chick Embryo; Culture Techniques; DNA; Fibroblasts; Hydroxyurea; Leucine; Microscopy, Phase-Contrast; Mitosis; Photometry; Thymidine; Time Factors; Tritium; Uridine | 1971 |
Cross-linking of DNA by alkylating agents and effects on DNA function in the chick embryo.
Topics: Animals; Chick Embryo; Depression, Chemical; DNA; Hydroxyurea; Leucine; Mechlorethamine; Mitomycins; Nucleic Acid Denaturation; Protein Biosynthesis; RNA; Thiotepa; Thymidine; Tritium; Uridine | 1971 |
Use of 3 H-thymidine for measurement of DNA synthesis in rat liver--a warning.
Topics: Animals; Cells; DNA; Freezing; Hot Temperature; Hydroxyurea; Liver; Liver Regeneration; Male; Methods; Phenols; Protein Binding; Rats; Thymidine; Trichloroacetic Acid; Tritium | 1972 |
Repair DNA synthesis in differentiated embryonic muscle cells.
Topics: Animals; Autoradiography; Cell Differentiation; Cells, Cultured; Centrifugation, Density Gradient; Chick Embryo; Depression, Chemical; DNA; DNA Repair; DNA Replication; Hydroxyurea; In Vitro Techniques; Muscles; Pectoralis Muscles; Radiation Genetics; Thymidine; Ultraviolet Rays | 1972 |
Hydroxyurea and the differentiation of growth cartilage cells in the rat.
Topics: Animals; Autoradiography; Cartilage; Cell Differentiation; Cell Nucleus; Epiphyses; Hydroxyurea; Injections, Intraperitoneal; Male; Mitosis; Rats; Rats, Inbred Strains; Thymidine; Tibia; Time Factors; Tritium | 1972 |
Continuous inhibition of DNA synthesis in mouse ear epidermis using hydroxyurea.
Topics: Animals; Autoradiography; Depression, Chemical; DNA; Ear; Hydroxyurea; Male; Mice; Mice, Inbred Strains; Skin; Thymidine; Time Factors; Tritium | 1972 |
Postreplication repair of DNA in ultraviolet-irradiated mammalian cells.
Topics: Animals; Bromodeoxyuridine; Bromouracil; Cell Line; Centrifugation, Density Gradient; DNA; DNA Repair; DNA Replication; Hydroxyurea; In Vitro Techniques; Lymphoma; Mice; Molecular Weight; Pyrimidine Nucleotides; Radiation Effects; Templates, Genetic; Thymidine; Tritium; Ultraviolet Rays | 1972 |
Budding in hydra: the role of cell multiplication and cell movement in bud initiation.
Topics: Animals; Cell Count; Cell Movement; DNA; Food Deprivation; Hydra; Hydroxyurea; Mitosis; Thymidine; Transplantation, Homologous; Tritium | 1972 |
Effect of hydroxyurea and trisethyleneiminobenzoquinone (Trenimon) on the methylation of DNA in Ehrlich ascites tumor cells.
Topics: Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Chromatography, Paper; Cytidine; Cytosine Nucleotides; Depression, Chemical; DNA, Neoplasm; Hydroxyurea; Mathematics; Methionine; Methylation; Mice; Thymidine; Triaziquone; Tritium | 1972 |
Comparison of the action of 3 H-thymidine and hydroxyurea on testosterone-treated hemopoietic stem cells.
Topics: Animals; Bone Marrow Cells; Cells, Cultured; Clone Cells; DNA; Female; Hematopoietic Stem Cells; Hydroxyurea; Mice; Radiation Chimera; Ribonucleotides; Spleen; Testosterone; Thymidine; Tritium | 1972 |
Time course of the effect of AAF on mouse liver nucleic acid synthesis and its modification by inhibitors.
Topics: Acetates; Animals; Centrifugation, Density Gradient; Cycloheximide; Dactinomycin; DNA; Fluorenes; Hydroxyurea; Leucine; Liver; Male; Mice; Orotic Acid; Protein Biosynthesis; RNA; RNA Nucleotidyltransferases; RNA, Ribosomal; RNA, Transfer; Thymidine; Time Factors; Tritium; Uridine; Urinary Bladder | 1972 |
Prolonged ultraviolet-induced thymidine incorporation into xeroderma pigmentosum lymphocytes: studies on its duration, amount, localization and relationship to hydroxyurea.
Topics: Autoradiography; Cell Nucleus; Cells, Cultured; DNA; DNA Repair; Humans; Hydroxyurea; Lymphocytes; Radiation Effects; Thymidine; Time Factors; Tritium; Ultraviolet Rays; Xeroderma Pigmentosum | 1972 |
Erythropoietin effects on fetal mouse erythroid cells. II. Nucleic acid synthesis and the erythropoietin-sensitive cell.
Topics: Animals; Autoradiography; Carbon Isotopes; Cell Differentiation; Cells, Cultured; Cytosine Nucleotides; DNA; Embryo, Mammalian; Erythropoietin; Gestational Age; Hydroxyurea; Liver; Mice; RNA; Stimulation, Chemical; Thymidine; Tritium; Uridine | 1972 |
Comparative studies on induction and rejoining of DNA single-strand breaks by radiation and chemical carcinogen in mammalian cells in vitro.
Topics: Animals; Bromodeoxyuridine; Carcinogens; Carcinoma, Ehrlich Tumor; Cells, Cultured; Centrifugation, Density Gradient; Dactinomycin; DNA; DNA Repair; DNA Replication; Hot Temperature; Hydroxylamines; Hydroxyurea; Kidney; Kinetics; L Cells; Molecular Weight; Puromycin; Quinolines; Radiation Effects; Swine; Thymidine; Tritium | 1972 |
A direct in vitro assay for studying radiosensitization in mammalian cells.
Topics: Animals; Biopsy; Cells, Cultured; Dactinomycin; DNA Repair; DNA Replication; DNA, Neoplasm; Evaluation Studies as Topic; Hydroxyurea; Leukemia L1210; Mice; Radiation-Sensitizing Agents; Thymidine; Tritium | 1972 |
Camptothecin effects on DNA synthesis in murine leukemia cells.
Topics: Alkaloids; Animals; Antineoplastic Agents; Carbon Isotopes; Cell Division; Cell Line; Cells, Cultured; DNA, Neoplasm; Hydroxyurea; Kinetics; Leukemia L1210; Leukemia, Experimental; Mice; Thymidine; Time Factors | 1972 |
A genetic approach to the study of cytotoxicity and resistance of cultured Chinese hamster cells in the presence of cytosine arabinoside.
Topics: Animals; Arginine; Carbon Isotopes; Cell Fusion; Cell Line; Cell Survival; Cricetinae; Cytarabine; DNA; Drug Resistance; Genes, Recessive; Genetic Complementation Test; Hybrid Cells; Hydroxyurea; Leucine; Lung; Protein Biosynthesis; Puromycin; Thymidine; Time Factors; Tritium | 1972 |
Incorporation of 3 H-thymidine into deoxyribonucleic acid of mouse small intestine in vitro.
Topics: Age Factors; Animals; Body Weight; Chromatography, Ion Exchange; Culture Media; Culture Techniques; DNA; Female; Hydroxyurea; Intestine, Small; Mice; Thymidine; Tritium | 1972 |
Effect of hydroxyurea and cytarabine on rodent epidermal cells.
Topics: Animals; Animals, Newborn; Cell Nucleus; Cytarabine; Depression, Chemical; DNA Replication; Hydroxyurea; Mice; Mitosis; Necrosis; Psoriasis; Rats; Skin; Thymidine; Tritium | 1971 |
Radioautographic analysis of 7,12-dimethyl-benz(a)anthracene-3H incorporation and cell survival of Syrian hamster embryo cells during exposure to nucleic acid inhibitors.
Topics: Animals; Autoradiography; Benz(a)Anthracenes; Benzimidazoles; Cell Nucleus; Cricetinae; Culture Techniques; Dactinomycin; DNA; Embryo, Mammalian; Hydroxyurea; Nucleic Acids; RNA; Thymidine; Time Factors; Tritium; Uridine | 1971 |
[Synchronization of the cell cycle in solid tumors].
Topics: Animals; DNA; Female; Hydroxyurea; Mammary Neoplasms, Experimental; Mice; Mitosis; Periodicity; Radiation Effects; Rats; Sarcoma, Yoshida; Thymidine; Tritium | 1971 |
Synchronisation in vivo: temporary inhibition of DNA synthesis in the rat embryo with hydroxyurea.
Topics: Animals; Body Weight; DNA; Female; Fetus; Gestational Age; Half-Life; Hydroxyurea; Injections, Intraperitoneal; Maternal-Fetal Exchange; Mitosis; Pregnancy; Rats; Thymidine; Time Factors; Tritium | 1971 |
[The role of cytokinetically resting cells for the regeneration of an aplastic bone marrow. Autoradiographic studies on rat].
Topics: Animals; Animals, Newborn; Autoradiography; Bone Marrow; Bone Marrow Cells; Epithelium; Female; Hematopoiesis; Hydroxyurea; Lymphocytes; Mechlorethamine; Mononuclear Phagocyte System; Pregnancy; Radiation Injuries, Experimental; Rats; Regeneration; Thymidine; Tritium | 1971 |
Effects of selected arylhydroxamic acids on lymphocyte mitogenesis.
Topics: Benzoates; Cells, Cultured; Depression, Chemical; Humans; Hydroxamic Acids; Hydroxylamines; Hydroxyurea; In Vitro Techniques; Leucine; Lymphocyte Activation; Structure-Activity Relationship; Thymidine; Tritium; Uridine | 1971 |
Regulation of glucose 6-phosphate dehydrogenase formation in mammary organ culture.
Topics: Amino Acids; Animals; Colchicine; Culture Media; Cysteine; Dactinomycin; DNA; Female; Fructose; Glucose; Glucosephosphate Dehydrogenase; Glycerol; Hydroxyurea; Insulin; Kinetics; Mammary Glands, Animal; Mannose; Mice; Mice, Inbred Strains; Mitosis; Organ Culture Techniques; Phosphogluconate Dehydrogenase; Pregnancy; Prolactin; Pyruvates; RNA, Messenger; Thymidine; Time Factors; Tritium | 1971 |
Thymidine labeling of pyrimidine isostichs from human lymphocyte DNA during repair after damage with N-acetoxy acetylaminofluorene or nitrogen mustard.
Topics: Acetamides; Aniline Compounds; Chromatography, DEAE-Cellulose; DNA; DNA Repair; Fluorenes; Formates; Humans; Hydroxyurea; Lymphocytes; Mechlorethamine; Nitrogen Mustard Compounds; Pyrimidine Nucleotides; Thymidine; Tritium | 1971 |
An evaluation of radioiodine-labeled 5-iodo-2'-deoxyuridine as a tracer for measuring cell loss from solid tumors.
Topics: Animals; Autoradiography; Cell Count; DNA; DNA, Neoplasm; Duodenum; Female; Hydroxyurea; Idoxuridine; Intestinal Mucosa; Iodine Isotopes; Mammary Neoplasms, Experimental; Methods; Mice; Mice, Inbred Strains; Skin; Thymidine; Time Factors; Tritium | 1971 |
X-ray survival response of the mouse L cells.
Topics: Animals; Cell Survival; Cells, Cultured; DNA; HeLa Cells; Hydroxyurea; L Cells; Mice; Mitosis; Radiation Dosage; Radiation Effects; Thymidine; Tritium | 1971 |
DNA synthesis inhibition and cell death associated with hydroxyurea teratogenesis in rat embryos.
Topics: Abnormalities, Drug-Induced; Animals; Cell Division; Central Nervous System; DNA; Embryo, Mammalian; Female; Forelimb; Gestational Age; Hindlimb; Hydroxyurea; Pregnancy; Rats; Rats, Inbred Strains; Thymidine; Tritium | 1971 |
Deoxyribonucleoside triphosphate pools in synchronized and drug-inhibited L 929 cells.
Topics: Adenine Nucleotides; Aminopterin; Animals; Autoradiography; Cell Line; Cell Nucleus; Cytosine Nucleotides; Deoxyribonucleotides; Depression, Chemical; DNA; Guanine Nucleotides; Hydroxyurea; Kinetics; Mice; Nucleotides; Stimulation, Chemical; Thymidine; Thymine Nucleotides; Time Factors; Tritium | 1971 |
X-ray survival and DNA synthesis in Chinese hamster cells. I. The effect of inhibitors added before x-irradiation.
Topics: Animals; Antifungal Agents; Antineoplastic Agents; Cell Division; Cricetinae; Culture Techniques; Cycloheximide; Dactinomycin; DNA; Hydroxyurea; Radiation Effects; Thymidine; Tritium; Urea | 1967 |
In vitro studies on DNA synthesis of bone marrow cells stimulated by erythropoietin.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Culture Techniques; DNA; Erythropoietin; Hydroxyurea; Male; Rats; Thymidine; Tritium | 1968 |
X-radiation survival in mammalian cells and inhibitors of macromolecular synthesis. ANL-7409.
Topics: Animals; Cell Division; Cell Line; Cricetinae; Cycloheximide; Dactinomycin; DNA; Hydroxyurea; Protein Biosynthesis; Radiation Effects; RNA; Thymidine; Time Factors | 1967 |
Ultra-violet-light-enhanced precursor incorporation and the repair of DNA damage.
Topics: Bromodeoxyuridine; Centrifugation, Density Gradient; Culture Techniques; Dactinomycin; DNA; Humans; Hydroxyurea; Kidney; Nucleosides; Radiation Effects; Thymidine; Tritium; Ultraviolet Rays | 1969 |
The influence of post-irradiation conditions on the survival of Chinese hamster cells after gamma-irradiation.
Topics: Acridines; Animals; Caffeine; Chloramphenicol; Cricetinae; Culture Techniques; Cycloheximide; Cytarabine; Dactinomycin; DNA; Hydroxylamines; Hydroxyurea; Protein Binding; Protein Biosynthesis; Puromycin; Radiation Effects; Temperature; Thymidine | 1970 |
Characteristics of "repair synthesis" in x-irradiated P388F lymphoma cells.
Topics: Autoradiography; Cell Line; Centrifugation, Density Gradient; Cesium; Culture Techniques; Deoxyuridine; DNA, Neoplasm; Humans; Hydroxyurea; Lymphoma; Radiation Effects; Thymidine; Time Factors; Tritium | 1970 |
Hydroxyurea derivatives: oxamyl hydroxamic acid.
Topics: Animals; Antineoplastic Agents; Bacterial Proteins; Carbon Isotopes; Carcinoma, Ehrlich Tumor; DNA, Bacterial; DNA, Neoplasm; Escherichia coli; Hydroxamic Acids; Hydroxyurea; In Vitro Techniques; Leucine; Methemoglobin; Mice; Microscopy, Electron; Neoplasm Proteins; RNA, Bacterial; RNA, Neoplasm; Spectrum Analysis; Thymidine; Tritium; Urea; Uridine | 1966 |
Histone synthesis in vitro on HeLa cell microsomes. The nature of the coupling to deoxyribonucleic acid synthesis.
Topics: Benzimidazoles; Cell-Free System; Cytoplasm; Dactinomycin; Depression, Chemical; DNA Replication; DNA, Neoplasm; HeLa Cells; Histones; Hydroxyurea; In Vitro Techniques; Leucine; Lysine; Methods; Microsomes; RNA, Messenger; RNA, Neoplasm; Thymidine; Time Factors; Tritium; Uridine | 1969 |
Spontaneous unscheduled DNA synthesis in GI HeLa cells.
Topics: Acridines; Autoradiography; DNA, Neoplasm; HeLa Cells; Hydroxyurea; Thymidine; Tritium | 1969 |
Repair incorporation of pyrimidine deoxynucleosides into DNA of mammalian cells exposed to UV light.
Topics: Autoradiography; Bromodeoxyuridine; Centrifugation, Density Gradient; Culture Techniques; DNA; Humans; Hydroxyurea; Nucleosides; Radiation Effects; Thymidine; Tritium; Ultraviolet Rays | 1969 |
Hydroxyurea: effect on leucine, uridine, and thymidine triphosphate incorporation by rat liver mitochondria in vitro.
Topics: Animals; Carbon Isotopes; Chloramphenicol; Culture Techniques; Cycloheximide; DNA; Hydroxyurea; Leucine; Mitochondria, Liver; Nucleotides; Rats; Thymidine; Tritium; Uridine | 1969 |
Biochemical changes during development of mouse mammary tissue in organ culture.
Topics: Animals; Carbon Isotopes; Caseins; Colchicine; Corticosterone; Culture Techniques; Cycloheximide; Dactinomycin; DNA; Female; Glucose; Hydroxyurea; Insulin; Mammary Glands, Animal; Mice; Organ Culture Techniques; Phosphates; Phosphorus Isotopes; Pregnancy; Prolactin; RNA; Stimulation, Chemical; Thymidine; Tritium; Uridine | 1970 |
Synchronisation in vivo: kinetics of a malignant cell system following temporary inhibition of DNA synthesis with hydroxyurea.
Topics: Animals; Autoradiography; Carcinoma; Culture Techniques; DNA, Neoplasm; Hydroxyurea; Kinetics; Mammary Neoplasms, Experimental; Mitosis; Neoplasm Transplantation; Rats; Thymidine; Time Factors; Tritium | 1970 |
Partial synchronization of hamster embryonic cells in secondary culture.
Topics: Animals; Cell Line; Cricetinae; Culture Techniques; DNA; Embryo, Mammalian; Hydroxyurea; Mitosis; Thymidine | 1970 |
Renal adaptation during chronic NH4Cl acidosis in the rat: no role for hyperplasia.
Topics: Acidosis; Adaptation, Physiological; Ammonium Chloride; Animals; Cell Division; DNA; Functional Laterality; Hydroxyurea; Kidney; Kidney Diseases; Organ Size; Rats; Thymidine; Tritium | 1970 |
The age sensitivity of epithelial cells of mouse small intestine.
Topics: Animals; Cell Division; DNA; Epithelial Cells; Epithelium; Female; Hydroxyurea; Intestine, Small; Jejunum; Mice; Radiation Effects; Thymidine; Time Factors; Tritium | 1970 |
Unabated renal hypertrophy in uninephrectomized rats treated with hydroxyurea.
Topics: Animals; Colorimetry; DNA; Hydroxyurea; Hyperplasia; Hypertrophy; Kidney; Kidney Diseases; Male; Nephrectomy; Organ Size; Protein Biosynthesis; Rats; RNA; Thymidine; Time Factors; Tritium | 1970 |
Cell killing and the accumulation of breaks in the DNA of HEp-2 cells incubated in the presence of hydroxyurea.
Topics: Antimetabolites; Carcinoma; Cell Line; Centrifugation, Density Gradient; Culture Techniques; Cycloheximide; Depression, Chemical; DNA Replication; DNA, Neoplasm; Humans; Hydroxyurea; Laryngeal Neoplasms; Thymidine; Tritium | 1970 |
Inhibition of ribonucleotide reductase, DNA synthesis, and L1210 leukemia by guanazole.
Topics: Adenine; Animals; Azaguanine; Carbon Isotopes; Carcinoma, Squamous Cell; Culture Techniques; DNA, Neoplasm; Female; Formates; Hydroxyurea; Hypoxanthines; Leucine; Leukemia L1210; Male; Mice; Neoplasm Proteins; Oxidoreductases; RNA, Neoplasm; Thymidine; Tritium; Uridine | 1970 |
Inhibition of thymidine phosphorylation and DNA and histone synthesis in Ehrlich ascites carcinoma.
Topics: Aldehydes; Animals; Arginine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Chromatography, Thin Layer; Cycloheximide; Cytarabine; Cytoplasm; DNA; Glycine; Histones; Hydroxyurea; In Vitro Techniques; Lysine; Mice; Mitomycins; Nucleotides; Orotic Acid; Puromycin; Thiosemicarbazones; Thymidine; Tritium | 1970 |
A probable role for protein synthesis in intestinal epithelial cell damage induced in vivo by cytosine arabinoside, nitrogen mustard, or X-irradiation.
Topics: Animals; Carbon Isotopes; Chemical Phenomena; Chemistry; Cycloheximide; Cytarabine; DNA; Epithelium; Hydroxyurea; Intestinal Mucosa; Intestine, Small; Ketones; Leucine; Male; Mechlorethamine; Protein Biosynthesis; Proteins; Pyrroles; Radiation Effects; Rats; RNA; Thymidine; Time Factors | 1970 |
Induction of unscheduled DNA synthesis by half-nucleus irradiation of HeLa cells with an UV-microbeam in combination with hydroxyurea treatment.
Topics: Autoradiography; Cell Nucleus; DNA; HeLa Cells; Hydroxyurea; Mitosis; Radiation Effects; Thymidine; Tritium; Ultraviolet Rays | 1970 |
Unscheduled DNA synthesis at low X-ray doses.
Topics: DNA; DNA Replication; Half-Life; Humans; Hydroxyurea; In Vitro Techniques; Kinetics; Lymphocytes; Radiation Genetics; Thymidine; Tritium | 1970 |
[Quick method for sensitivity tests of malignant tumors against antineoplastic agents].
Topics: DNA; Hydroxyurea; Neoplasms; Thymidine; Tritium | 1970 |
The role of slowly proliferating cells in rat bone marrow during regeneration following hydroxyurea.
Topics: Animals; Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Count; Cell Division; Female; Hematopoiesis; Hydroxyurea; Lymphocytes; Pregnancy; Rats; Regeneration; Thymidine; Tritium | 1970 |
Comparison of cytotoxicity of hydroxyurea in normal and rapidly proliferating epidermis and small intestine in mice.
Topics: Animals; Autoradiography; Cell Division; Croton Oil; DNA; Female; Hydroxyurea; Injections, Intraperitoneal; Intestinal Mucosa; Intestine, Small; Mice; Mitosis; Radiation Effects; Skin; Sodium Chloride; Thymidine; Time Factors; Tritium | 1971 |
Analysis of DNA synthesis during meiotic prophase in Lilium.
Topics: Bromodeoxyuridine; Centrifugation, Density Gradient; Chromosomes; Crossing Over, Genetic; DNA; DNA Replication; Hybridization, Genetic; Hydroxyurea; Meiosis; Phosphorus Isotopes; Plants; Protein Denaturation; Thymidine; Tritium | 1971 |
Nuclear and kinetoplastic DNA replication cycles in normal and synchronously dividing Crithidia luciliae.
Topics: Animals; Autoradiography; Cell Division; Cell Nucleus; DNA; DNA Replication; Eukaryota; Histocytochemistry; Hydroxyurea; Mitosis; Thymidine; Tritium | 1971 |
The effect of x-irradiation on thymidine kinase activity in synchronous populations of HeLa cells.
Topics: Cell Division; Chromatography, DEAE-Cellulose; Colchicine; Cycloheximide; Dactinomycin; DNA; HeLa Cells; Hydroxyurea; Periodicity; Radiation Effects; Thymidine; Thymidine Kinase | 1971 |
Differential response of mitochondrial and nuclear DNA syntheses to hydroxyurea in normal and regenerating rat liver.
Topics: Animals; Carbon Isotopes; Cell Nucleus; Centrifugation, Density Gradient; Deoxyribonucleases; DNA; Hepatectomy; Hydroxyurea; Kinetics; Liver; Liver Regeneration; Male; Mitochondria, Liver; Rats; Spleen; Thymidine; Thymus Gland; Ultracentrifugation | 1971 |
Hydroxyurea: possible relationship of cytotoxicity to inhibition of skin carcinogenesis.
Topics: Animals; Carcinogens; Croton Oil; DNA; DNA, Neoplasm; Female; Hydroxyurea; Injections, Intraperitoneal; Mice; Neoplasms, Experimental; Skin; Skin Neoplasms; Thymidine; Time Factors; Tritium | 1971 |
Studies on the mechanism of action of progesterone in regulation of the synthesis of specific protein.
Topics: Amino Acids; Animals; Chickens; Colchicine; Culture Techniques; Cycloheximide; Dactinomycin; Diethylstilbestrol; Estrogens; Female; Fluorouracil; Hydroxyurea; Mitosis; Muramidase; Ovalbumin; Oviducts; Progesterone; Protein Biosynthesis; RNA; RNA Nucleotidyltransferases; Thymidine; Tritium; Uridine | 1968 |
Action of hydroxyurea on multiplication of influenza virus in mammalian cells.
Topics: Cell Division; DNA, Viral; Hemagglutination Tests; Hydroxyurea; Orthomyxoviridae; Thymidine; Tritium | 1968 |
Reduced binding of carcinogenic hydrocarbons to DNA of mouse skin during inhibition of DNA synthesis.
Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; DNA; Hydroxyurea; In Vitro Techniques; Male; Mice; Protein Binding; Skin; Thymidine; Tritium; Uridine | 1968 |
The combined effect of hydroxyurea and x-rays on Chinese hamster cells in vitro.
Topics: Animals; Cricetinae; Culture Techniques; DNA; Hydroxyurea; Mitosis; Radiation Effects; Thymidine; Time Factors | 1968 |
Viruses and renal carcinoma of Rana pipiens. VI. Interrelationships of macromolecular synthesis and infectious virus production in frog virus 3-infected BHK 21/13 cells.
Topics: Adenine; Animals; Anura; Carbon Isotopes; Culture Techniques; Cycloheximide; Cytarabine; Dactinomycin; DNA; DNA, Viral; Herpesviridae; Hydroxyurea; Idoxuridine; Inclusion Bodies, Viral; Kidney Neoplasms; Leucine; Neoplasms, Experimental; Oncogenic Viruses; Protein Biosynthesis; RNA; RNA, Viral; Thymidine; Tritium; Uridine; Viral Proteins; Virus Replication | 1968 |
Studies on thymidine kinase, thymidylate kinase, and deoxycytidylate deaminase of Chang liver cells.
Topics: Aminohydrolases; Carbon Isotopes; Culture Techniques; Cytosine Nucleotides; Dactinomycin; DNA; Feedback; Growth; Humans; Hydroxyurea; Liver; Methotrexate; Mitomycins; Nucleosides; Nucleotides; Phosphotransferases; Puromycin; Thymidine; Thymidine Kinase; Time Factors | 1968 |
Inhibitory action of hydroxyurea on nucleic acid synthesis in cultures of human lymphocytes stimulated by pokeweed mitogen.
Topics: Culture Techniques; Depression, Chemical; DNA; Drug Antagonism; Humans; Hydroxyurea; Lymphocytes; Mitosis; Plants; RNA; Stimulation, Chemical; Thymidine; Tritium | 1968 |
Hydroxyurea derivatives--1-methyl-1-hydroxyurea and 1-ethyl-1-hydroxyurea.
Topics: Animals; Carcinoma, Ehrlich Tumor; Depression, Chemical; DNA, Neoplasm; Drug Antagonism; Hydroxyurea; Leucine; Male; Mice; Neoplasm Proteins; Nucleosides; RNA, Neoplasm; Statistics as Topic; Thymidine; Tritium; Uridine | 1968 |
Hydroxyurea: inhibition of DNA-synthesis and selective susceptibility of S-phase cells in vivo.
Topics: Animals; DNA; Hydroxyurea; Mice; Mitosis; Rats; Thymidine | 1968 |
Hydroxyurea derivatives: 1-hydroxybiuret and 3-hydroxybiuret.
Topics: Animals; Antimetabolites; Carcinoma, Ehrlich Tumor; Depression, Chemical; DNA, Neoplasm; Hydroxyurea; Leucine; Neoplasm Proteins; Nucleosides; Pseudomonas; Spectrophotometry; Thymidine; Uridine | 1968 |
Effects of hydroxyurea on DNA and RNA synthesis in mouse skin, liver, and thymus and on skin tumorigenesis initiated by beta-propiolactone.
Topics: Animals; DNA Replication; Hydroxyurea; Injections, Intraperitoneal; Lactones; Liver; Mice; Propionates; RNA; Skin; Skin Neoplasms; Thymidine; Thymus Gland; Tritium | 1968 |
Evidence for excision of ultraviolet-induced pyrimidine dimers from the DNA of human cells in vitro.
Topics: Amnion; Caffeine; Cell Line; DNA; Female; HeLa Cells; Humans; Hydroxyurea; Lung; Polymers; Pyrimidines; Radiation Effects; Thymidine; Time Factors; Tritium; Ultraviolet Rays | 1968 |
On the mechanism of action of aldosterone on sodium transport: effect of inhibitors of DNA synthesis.
Topics: Aldosterone; Animals; Antibiotics, Antineoplastic; Anura; Biological Transport; DNA; DNA Nucleotidyltransferases; Hydroxyurea; In Vitro Techniques; Mineralocorticoid Receptor Antagonists; Sodium; Stimulation, Chemical; Thymidine; Tritium; Urinary Bladder | 1968 |
DNA synthesis in the developing rat brain.
Topics: Adenine; Aging; Animals; Animals, Newborn; Brain; Brain Chemistry; Carbon Isotopes; Cell-Free System; Cerebellum; Cerebral Cortex; Dactinomycin; Depression, Chemical; DNA; Hydroxyurea; Hypothalamus; Limbic System; Medulla Oblongata; Organ Size; Pons; Rats; RNA; Thymidine | 1969 |
Differential effects of hydroxyurea on survival of proliferating cells in vivo.
Topics: Animals; Cell Biology; Depression, Chemical; DNA; Epithelial Cells; Folic Acid; Hydroxyurea; Intestine, Small; Isoproterenol; Kidney; Liver Regeneration; Lymphoid Tissue; Male; Mice; Mitosis; Necrosis; Rats; Salivary Glands; Thymidine; Tongue; Tritium | 1969 |
[Effects of hydroxyurea on Acetabularia mediterranea].
Topics: Cell Nucleus; Centrifugation, Density Gradient; Cytoplasm; Darkness; Depression, Chemical; DNA; Eukaryota; Hydroxyurea; Morphogenesis; RNA; Temperature; Thymidine; Time Factors; Tritium; Uridine | 1969 |
Studies on the nature of replicating DNA of HeLa cells.
Topics: Alkalies; Cell Nucleus; Centrifugation, Density Gradient; Culture Techniques; Depression, Chemical; DNA Replication; HeLa Cells; Humans; Hydroxyurea; Temperature; Thymidine; Time Factors; Tritium; Vibration | 1969 |
The in vivo methylation of DNA in mouse fibroblasts.
Topics: Animals; Colorimetry; Culture Techniques; Cytosine; Depression, Chemical; DNA; DNA Replication; Drug Stability; Fibroblasts; Hydroxyurea; L Cells; Methionine; Methylation; Mice; Mitosis; Protein Biosynthesis; Pyrimidines; Thymidine; Time Factors; Tritium | 1969 |
The effect of hydroxyurea on differentiated marrow erythroid precursors.
Topics: Animals; Autoradiography; Bone Marrow; Bone Marrow Cells; DNA; Erythrocytes; Erythropoiesis; Female; Hydroxyurea; Injections, Intravenous; Methods; Mice; Mitosis; Thymidine; Time Factors; Tritium | 1969 |
Purified cytoplasmic DNA from HeLa cells: resistance to inhibition by hydroxyurea.
Topics: Carbon Isotopes; Cell Nucleus; Centrifugation, Density Gradient; Cytoplasm; DNA; HeLa Cells; Hydroxyurea; Thymidine; Tritium | 1969 |
Difference in the action of acriflavine and hydroxyurea on synthesis of macromolecules in a mammalian cell system in vitro.
Topics: Acridines; Antineoplastic Agents; Carbon Isotopes; Culture Techniques; DNA; Humans; Hydroxyurea; Phenylalanine; RNA; Thymidine; Tritium; Urea; Uridine | 1966 |
Hydroxyurea: effects on Chinese hamster cells grown in culture.
Topics: Animals; Antineoplastic Agents; Cell Division; Cricetinae; Culture Techniques; DNA; Hydroxyurea; Leucine; Radiation Effects; Thymidine; Tritium; Urea; Uridine | 1967 |
Inhibition of DNA synthesis in HeLa cells by hydroxyurea.
Topics: Antineoplastic Agents; Cell Division; Culture Techniques; DNA; HeLa Cells; Humans; Hydroxyurea; Leucine; Protein Biosynthesis; RNA; Thymidine; Urea; Uridine | 1967 |
Hydroxyurea. I. Acute cell death in proliferating tissues in rats.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Chromatography, Thin Layer; DNA; Duodenum; HeLa Cells; Hydroxamic Acids; Hydroxylamines; Hydroxyurea; Intestinal Mucosa; Intestine, Small; Rats; Thymidine; Thymus Gland; Urea; Urethane | 1967 |
Hydroxyurea-induced inhibition of deoxyribonucleotide synthesis: studies in intact cells.
Topics: Antineoplastic Agents; Carbon Isotopes; Culture Techniques; DNA; Echinodermata; Embryo, Nonmammalian; HeLa Cells; Hydroxyurea; Leucine; Nucleosides; Nucleotides; Thymidine; Tritium; Urea; Uridine | 1967 |
Inhibition of DNA synthesis by hydroxyurea: structure-activity relationships.
Topics: Antineoplastic Agents; Culture Techniques; DNA; Guanidines; HeLa Cells; Hydroxamic Acids; Hydroxylamines; Hydroxyurea; Leucine; Thymidine; Urea; Uridine | 1967 |
Hydroxyurea reversal of inhibition and use as a cell-synchronizing agent.
Topics: Animals; Culture Techniques; DNA; Enzymes; Fibroblasts; Hydroxyurea; L Cells; Mice; Nucleosides; Nucleotides; Oxidative Phosphorylation; Oxidoreductases; Purines; Pyrimidines; Thymidine; Tritium; Urea | 1967 |
Responses of synchronous populations of HeLa cells to ultraviolet irradiation at selected stages of the generation cycle.
Topics: Autoradiography; Carbon Isotopes; Cell Division; Coliphages; Culture Techniques; DNA; HeLa Cells; Hydroxyurea; Mitosis; Radiation Effects; Thymidine; Tritium; Ultraviolet Rays; Uracil Nucleotides; Vinblastine | 1967 |
Incomplete inhibition of synchronized cell division by hydroxyurea and its relevance to the normal cellular life cycle.
Topics: Amino Acids; Animals; Carbon Isotopes; Cell Division; Cell Nucleus; DNA; Hydroxyurea; Kinetics; RNA; RNA, Messenger; Spectrophotometry; Tetrahymena; Thymidine; Tritium | 1967 |
DNA synthesis in scrapie-affected mouse brain.
Topics: Animals; Brain; Carbon Isotopes; DNA; Hydroxyurea; Idoxuridine; Mice; Scrapie; Sheep; Thymidine; Tritium | 1967 |
Comparison of the effectiveness of S phase inhibitors in altering gene expression.
Topics: Animals; Azacitidine; Cell Line; Cell Survival; Cytarabine; Female; Genes; Hydroxyurea; Hypoxanthine Phosphoribosyltransferase; Interphase; Kinetics; Mice; Thymidine; Transcription, Genetic; X Chromosome | 1984 |
Use of primary cultures of adult rat hepatocytes to investigate mechanisms of action of nafenopin, a hepatocarcinogenic peroxisome proliferator.
Topics: Animals; Cells, Cultured; DNA; DNA Repair; gamma-Glutamyltransferase; Hydroxyurea; Liver; Liver Neoplasms; Male; Microbodies; Nafenopin; Propionates; Rats; Rats, Inbred Strains; Thymidine | 1984 |
Antimitotic drugs that enhance neuronal survival in olfactory bulb cell cultures.
Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Cytarabine; Depression, Chemical; Floxuridine; Hydroxyurea; Methotrexate; Mitosis; Olfactory Bulb; Potassium; Rats; Rats, Inbred Strains; Thymidine | 1983 |
[Effects of Epimedium sagittatum and Cistanche deserticola on DNA synthesis in "Yang-insufficiency" animal model induced by hydroxyurea].
Topics: Animals; China; Disease Models, Animal; DNA; Drug Combinations; Hydroxyurea; Male; Mice; Plant Extracts; Plants, Medicinal; Thymidine | 1984 |
G1-phase arrest of cultured human leukemic T-cells induced by deoxyadenosine.
Topics: Adenosine Kinase; B-Lymphocytes; Cell Cycle; Cell Transformation, Viral; Cells, Cultured; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Deoxyribonucleosides; Flow Cytometry; Herpesvirus 4, Human; Humans; Hydroxyurea; Leukemia, Lymphoid; T-Lymphocytes; Thymidine | 1981 |
Effects of hydroxyurea and benzo(a)pyrene on DNA synthesis in the isolated perfused rat lung.
Topics: Animals; Benzo(a)pyrene; Benzopyrenes; DNA; Hydroxyurea; Lung; Male; Rats; Thymidine | 1982 |
International Workshop on inhibition of DNA repair. King's College, Cambridge, U.K., 29th June-2nd July 1982.
Topics: Animals; Aphidicolin; Arabinose; Dideoxynucleosides; Diterpenes; DNA Repair; Humans; Hydroxyurea; Thymidine | 1983 |
Kinetics of thymidine incorporation into detergent-soluble DNA of mouse lymphocytes.
Topics: Animals; Aphidicolin; Detergents; Diterpenes; DNA; DNA Replication; Hydroxyurea; Lymphocyte Activation; Lymphocytes; Mice; Molecular Weight; Solubility; Thymidine | 1984 |
Mosaicism in female hybrid hares heterozygous for glucose-6-phosphate dehydrogenase. V. The recovery of DNA synthesis of hare fibroblasts after ultraviolet irradiation.
Topics: Animals; DNA Replication; Female; Fibroblasts; Glucosephosphate Dehydrogenase; Heterozygote; Hydroxyurea; Mosaicism; Rabbits; Thymidine; Time Factors; Ultraviolet Rays | 1984 |
Unscheduled DNA synthesis in cell lysate system reflecting DNA repair in vivo.
Topics: Cytarabine; Dideoxynucleosides; DNA; DNA Repair; HeLa Cells; Humans; Hydroxyurea; Thymidine; Ultraviolet Rays | 1984 |
Effects of S-phase-specific agents on granulocyte-macrophage and erythroid progenitor cells obtained from normal individuals and from patients with chronic myelogenous leukemia.
Topics: Adult; Aged; Bone Marrow Cells; Cytarabine; Female; Granulocytes; Hematopoietic Stem Cells; Humans; Hydroxyurea; Interphase; Leukemia, Myeloid; Macrophages; Male; Middle Aged; Thymidine | 1983 |
Combined cytotoxic effect of low-dose 5-fluorouracil and hydroxyurea on 9L cells in vitro.
Topics: Animals; Brain Neoplasms; Cell Line; Cell Survival; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Hydroxyurea; Kinetics; Rats; Thymidine | 1983 |
DNA in cytosol fractions obtained by differential centrifugation of homogenates of rapidly growing liver tumors.
Topics: Animals; Cell Nucleus; Cell Separation; Centrifugation; Cytosol; DNA; DNA, Neoplasm; Female; Hydroxyurea; Liver; Liver Neoplasms, Experimental; Male; Necrosis; Postmortem Changes; Rats; Thymidine | 1984 |
Schistosoma mansoni: DNA synthesis in males and females from mixed and single-sex infections.
Topics: Animals; Autoradiography; DNA; Female; Hydroxyurea; Male; Mice; Mice, Inbred Strains; Schistosoma mansoni; Schistosomiasis; Sex Characteristics; Thymidine; Tritium | 1984 |
Modulation of the cellular pharmacology and clinical toxicity of 1-beta-D-arabinofuranosylcytosine.
Topics: Arabinofuranosylcytosine Triphosphate; Cell Line; Cytarabine; Deoxyribonucleotides; DNA; Drug Therapy, Combination; Humans; Hydroxyurea; Leukemia; Ribonucleotide Reductases; Ribonucleotides; Thymidine | 1982 |
Inhibition of thymidylate synthase by hydroxyurea in rapidly proliferating P815 mastocytoma cells.
Topics: Animals; Deoxycytidine; Deoxyuridine; DNA, Neoplasm; Hydroxyurea; Mast-Cell Sarcoma; Methyltransferases; Mice; Thymidine; Thymidylate Synthase | 1982 |
Increased level of ribonucleotide reductase and associated resistance to aphidicolin in mouse FM3A cell mutants selected for simultaneous resistance to 9-beta-D-arabinofuranosyladenine and 1-beta-D-arabinofuranosylcytosine.
Topics: Animals; Aphidicolin; Cells, Cultured; Cytarabine; Diterpenes; DNA Polymerase II; Drug Resistance; Hydroxyurea; Mice; Mutation; Nucleic Acid Synthesis Inhibitors; Phenotype; Ribonucleotide Reductases; Thymidine; Vidarabine | 1982 |
Comparison of nucleoid and alkaline sucrose gradients in the analysis of inhibitors of DNA repair in human fibroblasts.
Topics: Aphidicolin; Benzamides; Cell Line; Cytarabine; Dideoxynucleosides; Diterpenes; DNA Polymerase I; DNA Polymerase II; DNA Repair; DNA Replication; DNA, Single-Stranded; Embryology; Fibroblasts; Humans; Hydroxyurea; Molecular Weight; Nucleic Acid Synthesis Inhibitors; Skin; Thymidine; Ultraviolet Rays | 1982 |
Effects of methotrexate in vitro on epidermal cell proliferation.
Topics: Animals; Cell Division; Cell Movement; Cells, Cultured; Culture Media; Dose-Response Relationship, Drug; Fetal Blood; Hot Temperature; Hydroxyurea; Methotrexate; Mitotic Index; Skin; Swine; Thymidine; Time Factors | 1983 |
The scintillometric evaluation of DNA repair synthesis can be distorted by changes of thymidine pool radioactivity.
Topics: Animals; Autoradiography; Cell Line; Chromatography, Thin Layer; Cricetinae; DNA; DNA Repair; DNA Replication; Humans; Hydroxyurea; Methyl Methanesulfonate; Scintillation Counting; Thymidine; Ultraviolet Rays | 1983 |
Isotope-dilution analysis of the effects of deoxyguanosine and deoxyadenosine on the incorporation of thymidine and deoxycytidine by hydroxyurea-treated thymus cells.
Topics: Animals; Cells, Cultured; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Hydroxyurea; Rats; Thymidine; Thymus Gland; Tritium | 1980 |
Inaccuracy of estimations of s phase fraction by reduction in cloning efficiency with hydroxyurea or tritiated thymidine.
Topics: B-Lymphocytes; Cell Line; Clone Cells; Dose-Response Relationship, Drug; Humans; Hydroxyurea; Interphase; Kinetics; Thymidine | 1981 |
Synergistic interaction between 1-beta-D-arabinofuranosylcytosine, thymidine, and hydroxyurea against human B cells and leukemic blasts in vitro.
Topics: Animals; B-Lymphocytes; Cells, Cultured; Cytarabine; DNA Replication; DNA, Neoplasm; Drug Synergism; Drug Therapy, Combination; Humans; Hydroxyurea; Leukemia, Experimental; Thymidine | 1981 |
Cell kinetics of lithium-induced granulopoiesis.
Topics: Animals; Bone Marrow; Colony-Forming Units Assay; Colony-Stimulating Factors; DNA; Dose-Response Relationship, Drug; Granulocytes; Hematopoiesis; Hydroxyurea; Lithium; Mice; Thymidine; Time Factors | 1982 |
Unbalanced growth and cell death in HeLa S3 cultures treated with DNA synthesis inhibitors.
Topics: Cell Division; Cell Survival; Cytological Techniques; DNA; HeLa Cells; Humans; Hydroxyurea; Interphase; Thymidine; Vinblastine | 1981 |
Analysis of the effect of hydroxyurea on stem cell (CFU-s) kinetics.
Topics: Animals; Cell Cycle; Cell Division; Cell Survival; Colony-Forming Units Assay; Female; Hematopoietic Stem Cells; Hydroxyurea; Interphase; Mice; Thymidine; Tritium | 1982 |
A long-lived thymidine pool in epithelial stem cells.
Topics: Animals; Autoradiography; Cell Division; Epithelial Cells; Epithelium; Female; Hydroxyurea; Male; Mice; Thymidine; Tongue; Vincristine | 1982 |
Regulation of thymidine kinase enzyme level in serum-stimulated mouse 3T6 fibroblasts.
Topics: Animals; Cell Cycle; Culture Media; Cytarabine; DNA Replication; Gene Expression Regulation; Growth Substances; Hydroxyurea; Mice; Thymidine; Thymidine Kinase; Transcription, Genetic | 1982 |
Role of dephosphorylation in accumulation of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate in human lymphoblastic cell lines with reference to their drug sensitivity.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cell Division; Cell Line; Cells, Cultured; Cytarabine; DNA, Neoplasm; Humans; Hydroxyurea; Leukemia; Lymphoma; Phosphorylation; Thymidine | 1982 |
Role of non-histones in chromosome structure. Cell cycle variations in protein synthesis.
Topics: Cell Cycle; Centrifugation, Density Gradient; Chromatin; Chromosomal Proteins, Non-Histone; Chromosomes; Densitometry; DNA Replication; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Hydroxyurea; Thymidine | 1982 |
Unscheduled DNA synthesis in rat liver after gastric administration of halothane.
Topics: Animals; Cell Nucleus; DNA; Halothane; Hydroxyurea; Intubation, Gastrointestinal; Liver; Male; Phenobarbital; Rats; Thymidine | 1982 |
Decreased sensitivity to hydroxyurea and to [3H]thymidine suicide in the middle of the S phase.
Topics: Animals; DNA; Hematopoietic Stem Cells; Hydroxyurea; Interphase; Mice; Thymidine | 1981 |
A simplified method for measuring scheduled and unscheduled DNA synthesis in human fibroblasts.
Topics: Carcinogens; DNA; DNA Repair; Drug Evaluation, Preclinical; Fibroblasts; Humans; Hydroxyurea; Thymidine | 1981 |
Effects of inhibitors of DNA synthesis and protein synthesis on the rate of DNA synthesis after exposure of mammalian cells to ultraviolet light.
Topics: Animals; Cell Line; Cricetinae; Cricetulus; Cycloheximide; DNA Replication; Hydroxyurea; Interphase; Kinetics; Protein Biosynthesis; Thymidine; Time Factors; Ultraviolet Rays | 1981 |
[Effect of a single dose of hydroxyurea on cell division in the esophageal and lingual epithelium of mice].
Topics: Animals; Dose-Response Relationship, Drug; Epithelium; Esophagus; Hydroxyurea; Male; Mice; Mitotic Index; Thymidine; Time Factors; Tongue | 1981 |
Differences in cytosol factors in liver and hepatomas revealed by real or apparent effects on the incorporation of [3H] thymidine.
Topics: Animals; Cell Division; Cell Extracts; Cell Fractionation; Cycloheximide; Cytosol; Ethanol; Hydroxyurea; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Male; Rats; Rats, Inbred BUF; Thymidine; Tissue Extracts | 1981 |
Hydroxyurea: effect on growth, structure, and [3H]thymidine uptake of Trypanosoma brucei procyclic culture forms.
Topics: Animals; Cell Division; Cell Nucleus; DNA Replication; Hydroxyurea; Organoids; Thymidine; Trypanosoma brucei brucei | 1980 |
Relationship between morphological transformation and [3H]thymidine incorporation stimulated by a chemical carcinogen in postconfluent cultures of hamster embryo cells.
Topics: Animals; Autoradiography; Caffeine; Carcinogens; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; DNA; Dose-Response Relationship, Drug; Embryo, Mammalian; Hydroxyurea; Mesocricetus; Methylnitronitrosoguanidine; Stimulation, Chemical; Theophylline; Thymidine | 1980 |
Replicative and unscheduled DNA synthesis in adriamycin-treated myocardial cells.
Topics: Animals; Autoradiography; Chromosomes; DNA; DNA Replication; Doxorubicin; Hydroxyurea; Mitosis; Myocardium; Rats; Thymidine | 1980 |
Influence of a marrow stromal factor on survival of hemopoietic stem cells in vitro.
Topics: Animals; Bone Marrow Cells; Cell Division; Cell Survival; Cells, Cultured; Culture Media; DNA; Hematopoietic Stem Cells; Hydroxyurea; Male; Mice; Spleen; Thymidine | 1980 |
The in vivo incorporation of triated thymidine into liver cell nuclear DNA in mice treated chronically with carbon tetrachloride or with diethylnitrosamine.
Topics: Animals; Bromodeoxyuridine; Carbon Tetrachloride Poisoning; Cell Nucleus; Diethylnitrosamine; DNA; DNA Repair; Fluorouracil; Hydroxyurea; Liver; Mice; Nitrosamines; Thymidine | 1980 |
A statistical analysis of murine stem cell suicide techniques.
Topics: Cell Cycle; Cell Survival; Colony-Forming Units Assay; Female; Granulocytes; Hydroxyurea; Macrophages; Statistics as Topic; Thymidine | 1980 |
Characterization of MCSF-induced proliferation and subsequent osteoclast formation in murine marrow culture.
Topics: Acid Phosphatase; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Calcitriol; Cell Division; Cell Fusion; Cells, Cultured; Female; Femur; Giant Cells; Hydroxyurea; Isoenzymes; Isotope Labeling; Macrophage Colony-Stimulating Factor; Male; Mice; Mice, Inbred C57BL; Osteoclasts; Tartrate-Resistant Acid Phosphatase; Thymidine; Tibia; Tritium | 1995 |
Effect of ultrasound on DNA synthesis in tumor cells.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Survival; Cold Temperature; DNA; DNA Repair; DNA Replication; Female; Hot Temperature; Hydroxyurea; Mice; Mice, Inbred CBA; Mice, Inbred Strains; Thymidine; Tritium; Tumor Cells, Cultured; Ultrasonics | 1995 |
Inhibition of erythroid differentiation in MEL cells by UV irradiation. Cell cycle and DNA repair activity.
Topics: Animals; Cell Cycle; DNA; DNA Damage; DNA Repair; Erythroid Precursor Cells; Hydroxyurea; Leukemia, Erythroblastic, Acute; Mice; Mitotic Index; S Phase; Thymidine; Tumor Cells, Cultured; Ultraviolet Rays | 1993 |
Inhibition of endothelial cell proliferation by platelet factor-4 involves a unique action on S phase progression.
Topics: Animals; Aorta; Capillaries; Cattle; Cell Cycle; Cell Division; Cells, Cultured; DNA; Endothelium, Vascular; Fetus; Flow Cytometry; Heart; Heparin; Humans; Hydroxyurea; Kinetics; Platelet Factor 4; Rabbits; Retinal Vessels; Thymidine | 1994 |
Potentiation of 2',3'-dideoxycytidine (ddC) by hydroxyurea and thymidine on the Moloney murine leukemia virus (MoMLV) early replicative steps.
Topics: 3T3 Cells; Animals; Drug Synergism; Hydroxyurea; Mice; Moloney murine leukemia virus; Thymidine; Transcription, Genetic; Virus Replication; Zalcitabine; Zidovudine | 1994 |
Iron reverses impermeable chelator inhibition of DNA synthesis in CCl 39 cells.
Topics: Animals; Cations, Divalent; Cell Line; Chelating Agents; Cricetinae; Cricetulus; DNA; DNA Replication; Electron Transport; Epidermal Growth Factor; Hydroxyurea; Iron; Kinetics; Lung; Pentetic Acid; Phenanthrolines; Thymidine | 1994 |
[Study of S phase synchronization of the human gastric cancer line HGT-1].
Topics: Adenocarcinoma; Flow Cytometry; Humans; Hydroxyurea; Middle Aged; S Phase; Stomach Neoplasms; Thymidine; Thymidine Kinase; Tumor Cells, Cultured | 1993 |
Oxaloacetate induces DNA synthesis and mitosis in primary cultured rat hepatocytes in the absence of EGF.
Topics: Animals; Carboxylic Acids; Cells, Cultured; DNA; DNA Replication; Dose-Response Relationship, Drug; Epidermal Growth Factor; Hydroxyurea; Kinetics; Liver; Male; Mitosis; Mitotic Index; Oxaloacetates; Rats; Rats, Sprague-Dawley; Thymidine; Time Factors; Transforming Growth Factor beta; Tritium | 1993 |
Macrophage colony-stimulating factor is indispensable for both proliferation and differentiation of osteoclast progenitors.
Topics: Animals; Animals, Newborn; Antibodies; Calcitriol; Cell Differentiation; Cell Division; Cells, Cultured; DNA; Female; Genes, fms; Hydroxyurea; Kinetics; Macrophage Colony-Stimulating Factor; Male; Mice; Mice, Inbred Strains; Osteoclasts; Receptor, Macrophage Colony-Stimulating Factor; Spleen; Stem Cells; Thymidine; Time Factors | 1993 |
DNA rearrangements in Euplotes crassus coincide with discrete periods of DNA replication during the polytene chromosome stage of macronuclear development.
Topics: Animals; Base Sequence; Chromosomes; Crosses, Genetic; DNA Replication; DNA Transposable Elements; DNA, Protozoan; Euplotes; Hydroxyurea; Polymerase Chain Reaction; Species Specificity; Thymidine; Thymine Nucleotides | 1995 |
The dual effect of mimosine on DNA replication.
Topics: Animals; Antiviral Agents; Aphidicolin; Cell Line; DNA; DNA Repair; DNA Replication; DNA, Viral; G1 Phase; HeLa Cells; Humans; Hydroxyurea; Mimosine; Nucleic Acid Synthesis Inhibitors; Proteins; Replication Origin; S Phase; Simian virus 40; Thymidine; Virus Replication | 1997 |
Deoxyribonucleoside triphosphate pool imbalances in vivo are associated with an increased retroviral mutation rate.
Topics: Cell Line; Deoxyribonucleotides; Genetic Vectors; Hydroxyurea; Mutation; Retroviridae; Thymidine; Zidovudine | 1998 |
Taxol, vincristine or nocodazole induces lethality in G1-checkpoint-defective human astrocytoma U373MG cells by triggering hyperploid progression.
Topics: Astrocytoma; Cell Cycle; Cell Cycle Proteins; Cell Death; Cell Division; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Enzyme Inhibitors; Fibroblasts; Flow Cytometry; Humans; Hydroxyurea; Karyotyping; Microtubule-Associated Proteins; Nocodazole; Paclitaxel; Phosphorylation; Polyploidy; Retinoblastoma Protein; Thymidine; Tumor Cells, Cultured; Tumor Suppressor Proteins; Vincristine | 1999 |
Hydroxyurea enhances the activities of didanosine, 9-[2-(phosphonylmethoxy)ethyl]adenine, and 9-[2-(phosphonylmethoxy)propyl]adenine against drug-susceptible and drug-resistant human immunodeficiency virus isolates.
Topics: Adenine; Anti-HIV Agents; Antineoplastic Agents; Didanosine; DNA, Viral; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; Humans; Hydroxyurea; Inhibitory Concentration 50; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Tenofovir; Thymidine | 1999 |
Induction of catecholamine synthesis in human neuroblastoma cells by replication inhibitors and sodium butyrate.
Topics: Amanitins; Antineoplastic Agents; Butyrates; Cyclic AMP; Cycloheximide; Dactinomycin; DNA Replication; Dopamine; Homovanillic Acid; Humans; Hydroxyurea; Kinetics; Neuroblastoma; Norepinephrine; Thymidine; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase; Vanilmandelic Acid | 1999 |
Terminal differentiation of human promyelocytic leukaemia cells, HL-60, during the G1 period.
Topics: Calcitriol; Cell Differentiation; DNA, Neoplasm; G1 Phase; HL-60 Cells; Humans; Hydroxyurea; Leukemia, Promyelocytic, Acute; Nocodazole; S Phase; Thymidine | 2001 |
Thymidine incorporation is highly predictive of colony formation and can be used for high-throughput screening.
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Survival; Chickens; CHO Cells; Colonic Neoplasms; Colony-Forming Units Assay; Cricetinae; Drug Screening Assays, Antitumor; Etoposide; Humans; Hydroxyurea; Kidney Neoplasms; Lung Neoplasms; Paclitaxel; Sensitivity and Specificity; Thymidine; Tritium; Tumor Cells, Cultured | 2001 |
2-Chloro-2'-deoxyadenosine inhibits DNA repair synthesis and potentiates UVC cytotoxicity in chronic lymphocytic leukemia B lymphocytes.
Topics: Alkylating Agents; Alkylation; Antimetabolites, Antineoplastic; Apoptosis; B-Lymphocytes; Caspase 3; Caspases; Cladribine; Depression, Chemical; DNA Damage; DNA Repair; DNA Replication; DNA, Neoplasm; Humans; Hydroxyurea; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasm Proteins; Neoplastic Stem Cells; Phosphorylation; Prodrugs; Radiation Tolerance; Radiation-Sensitizing Agents; Thymidine; Tumor Cells, Cultured; Ultraviolet Rays | 2002 |
Different roles for nonhomologous end joining and homologous recombination following replication arrest in mammalian cells.
Topics: Animals; Apoptosis; Cell Line; Cricetinae; DNA; DNA Damage; DNA Nucleotidyltransferases; DNA Replication; DNA-Binding Proteins; Flow Cytometry; Gene Expression Regulation; Humans; Hydroxyurea; Nucleic Acid Conformation; Nucleic Acid Synthesis Inhibitors; Rad51 Recombinase; Recombination, Genetic; S Phase; Thymidine | 2002 |
Ribonucleotide reductase and thymidine phosphorylation: two potential targets of azodicarbonamide.
Topics: Animals; Antineoplastic Agents; Azo Compounds; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Drug Interactions; Hydroxyurea; Immunosuppressive Agents; Methotrexate; Phosphorylation; Ribonucleotide Reductases; Thymidine; Thymine Nucleotides; Tumor Cells, Cultured | 2002 |
Combination of drugs and drug-resistant reverse transcriptase results in a multiplicative increase of human immunodeficiency virus type 1 mutant frequencies.
Topics: Animals; Anti-HIV Agents; COS Cells; Dose-Response Relationship, Drug; Drug Resistance, Viral; Genetic Vectors; HeLa Cells; HIV Reverse Transcriptase; HIV-1; Humans; Hydroxyurea; Lamivudine; Mutation; Reverse Transcriptase Inhibitors; Thymidine; Virus Replication; Zidovudine | 2002 |
Regulatory volume decrease is actively modulated during the cell cycle.
Topics: Adenosine Triphosphate; Carcinoma; Cell Cycle; Cell Size; Chloride Channels; Flow Cytometry; G1 Phase; Humans; Hydroxyurea; Hypotonic Solutions; Mitosis; Nasopharyngeal Neoplasms; Nitrobenzoates; Nucleic Acid Synthesis Inhibitors; S Phase; Tamoxifen; Thymidine; Tumor Cells, Cultured | 2002 |
Zinc(II)-mediated inhibition of a ribonuclease by an N-hydroxyurea nucleotide.
Topics: Endoribonucleases; Enzyme Inhibitors; Hydroxyurea; Kinetics; Ribonucleases; Structure-Activity Relationship; Thymidine; Zinc | 2003 |
RAD51 is involved in repair of damage associated with DNA replication in mammalian cells.
Topics: Animals; Apoptosis; Cell Line; Cricetinae; DNA Damage; DNA Repair; DNA Replication; DNA-Binding Proteins; Dose-Response Relationship, Drug; Etoposide; Hydroxyurea; Hypoxanthine Phosphoribosyltransferase; Kinetics; Models, Genetic; Rad51 Recombinase; Recombination, Genetic; Thymidine | 2003 |
The ORC1 cycle in human cells: I. cell cycle-regulated oscillation of human ORC1.
Topics: Aphidicolin; Bromodeoxyuridine; Cell Cycle; Cell Line; DNA; DNA-Binding Proteins; Enzyme Inhibitors; G1 Phase; HeLa Cells; Humans; Hydroxyurea; Microscopy, Confocal; Nucleic Acid Synthesis Inhibitors; Origin Recognition Complex; Peptide Hydrolases; Proteasome Endopeptidase Complex; S Phase; Thymidine; Time Factors | 2003 |
Differential contribution of inhibitory phosphorylation of CDC2 and CDK2 for unperturbed cell cycle control and DNA integrity checkpoints.
Topics: Bromodeoxyuridine; CDC2 Protein Kinase; CDC2-CDC28 Kinases; Cell Cycle; Cell Cycle Proteins; Coloring Agents; Cyclin-Dependent Kinase 2; DNA; DNA Damage; Flow Cytometry; Genes, Dominant; HeLa Cells; Histones; Humans; Hydroxyurea; Mitosis; Mutation; Nuclear Proteins; Phosphorylation; Protein-Tyrosine Kinases; Thymidine; Time Factors | 2003 |
CYTOTOXICITY OF HYDROXYUREA (NSC-32065) REVERSIBLE BY PYRIMIDINE DEOXYRIBOSIDES IN A MAMMALIAN CELL LINE GROWN IN VITRO.
Topics: Antimetabolites; Cell Line; Cricetinae; Hydroxyurea; In Vitro Techniques; Neoplasms; Neoplasms, Experimental; Nucleosides; Pyrimidine Nucleosides; Pyrimidines; Research; Thymidine; Tissue Culture Techniques; Urea | 1964 |
HYDROXYUREA: INHIBITORY EFFECT ON DNA METABOLISM.
Topics: Antineoplastic Agents; Cytosine Nucleotides; DNA; DNA, Neoplasm; Guanine Nucleotides; HeLa Cells; Humans; Hydroxyurea; Leucine; Neoplasms, Experimental; Nucleosides; Proteins; Research; RNA; Thymidine; Tissue Culture Techniques; Urea; Urethane; Uridine | 1964 |
STUDIES ON A METABOLIC DEFECT INDUCED BY HYDROXYUREA (NSC-32065).
Topics: Anemia; Anemia, Macrocytic; Animals; Antineoplastic Agents; Bone Marrow Cells; Cattle; Cytosine Nucleotides; DNA; gamma-Globulins; Hydroxyurea; Immunoglobulin G; Metabolic Diseases; Rats; Research; RNA; Serum Albumin; Serum Albumin, Bovine; Thymidine; Toxicology; Tritium; Urea | 1964 |
EFFECT OF HYDROXYUREA ON THE INCORPORATION OF THYMIDINE INTO EHRLICH ASCITES TUMOR CELLS.
Topics: Animals; Antineoplastic Agents; Carcinoma; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Hydroxyurea; Metabolism; Pharmacology; Research; Thymidine | 1964 |
HYDROXYUREA: A SPECIFIC INHIBITOR OF DEOXYRIBONUCLEIC ACID SYNTHESIS.
Topics: Antineoplastic Agents; Carbon Isotopes; DNA; DNA Replication; DNA, Bacterial; Escherichia coli; Hydroxyurea; Metabolism; Pharmacology; Radiometry; Research; Thymidine; Tritium; Uracil | 1965 |
Different viral rebound following discontinuation of antiretroviral therapy in cases of infection with viruses carrying L74V or thymidine-associated mutations.
Topics: Acquired Immunodeficiency Syndrome; Amino Acid Substitution; Anti-HIV Agents; CD4 Lymphocyte Count; Didanosine; Female; Genotype; HIV; Humans; Hydroxyurea; Male; Mutagenesis, Site-Directed; Mutation; RNA, Viral; Thymidine; Time Factors; Viral Load | 2004 |
Overproduction of thymidine by recombinant brevibacterium helvolum amplified with thymidine monophosphate phosphohydrolase gene from bacteriophage PBS2.
Topics: Bacterial Proteins; Bacteriophages; Brevibacterium; Chromatography, High Pressure Liquid; Cloning, Molecular; Drug Resistance, Bacterial; Fermentation; Fluorouracil; Hydroxyurea; Mutation; Nucleotidases; Phosphoric Monoester Hydrolases; Plasmids; Recombinant Proteins; Thymidine; Thymidine Monophosphate; Trimethoprim | 2004 |
Enhanced oligonucleotide-directed gene targeting in mammalian cells following treatment with DNA damaging agents.
Topics: Cell Count; Cell Line; DNA; DNA Damage; DNA Repair; DNA Replication; Electroporation; Etoposide; Flow Cytometry; Gene Targeting; Humans; Hydroxyurea; Mutagenesis, Site-Directed; Mutagens; Mutation; Oligonucleotides; Recombination, Genetic; Thymidine; Up-Regulation | 2004 |
Differential roles of XRCC2 in homologous recombinational repair of stalled replication forks.
Topics: Animals; Chromatin; Cricetinae; DNA Damage; DNA Repair; DNA Replication; DNA-Binding Proteins; Drug Hypersensitivity; G2 Phase; Histones; Humans; Hydroxyurea; Mutation; Recombination, Genetic; S Phase; Thymidine | 2005 |
Comparative analysis of expression of histone H2a genes in mouse.
Topics: Acetylation; Animals; Cell Cycle; Cell Line; Chromatin; Chromatin Immunoprecipitation; DNA; DNA Primers; DNA, Complementary; G1 Phase; Gene Expression Regulation; Histones; Hydroxyurea; Mice; Multigene Family; Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Thymidine; Time Factors | 2005 |
Synchronization in the cell cycle by inhibitors of DNA replication induces histone H2AX phosphorylation: an indication of DNA damage.
Topics: Aphidicolin; Cell Cycle; DNA Damage; DNA Replication; Fluorescence; Histones; HL-60 Cells; Humans; Hydroxyurea; Immunohistochemistry; Phosphorylation; Thymidine | 2006 |
Paclitaxel induced apoptosis in breast cancer cells requires cell cycle transit but not Cdc2 activity.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-Associated Death Protein; Blotting, Western; Breast Neoplasms; CDC2 Protein Kinase; Cell Cycle; Cell Line, Tumor; Cell Nucleus; Cell Survival; DNA Fragmentation; Estradiol; Flow Cytometry; Fulvestrant; Humans; Hydroxyurea; Inhibitor of Apoptosis Proteins; JNK Mitogen-Activated Protein Kinases; Microtubule-Associated Proteins; Microtubules; Neoplasm Proteins; Paclitaxel; Purines; RNA, Small Interfering; Roscovitine; Spindle Apparatus; Survivin; Thymidine; Transfection | 2007 |
Hydrogen peroxide-induced thymidine incorporation into cultured rat astrocytes.
Topics: Animals; Animals, Newborn; Astrocytes; Bucladesine; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Hydrogen Peroxide; Hydroxyurea; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Thymidine; Uridine | 2006 |
IQGAP1 translocates to the nucleus in early S-phase and contributes to cell cycle progression after DNA replication arrest.
Topics: Active Transport, Cell Nucleus; Animals; Cell Line, Tumor; Cell Nucleus; Cytoplasm; DNA Replication; Epithelial Cells; Fibroblasts; G1 Phase; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Hydroxyurea; Mice; Microscopy, Confocal; Osteosarcoma; Protein Interaction Domains and Motifs; ras GTPase-Activating Proteins; Rats; S Phase; Thymidine | 2011 |
Replication stress induces micronuclei comprising of aggregated DNA double-strand breaks.
Topics: Animals; Aphidicolin; Cell Line; DNA Breaks, Double-Stranded; DNA Replication; Histones; Humans; Hydroxyurea; Mice; Micronuclei, Chromosome-Defective; Mutation; Paclitaxel; Replication Protein A; RNA, Small Interfering; S Phase; Stress, Physiological; Thymidine | 2011 |
Cyclin-dependent kinase subunit (Cks) 1 or Cks2 overexpression overrides the DNA damage response barrier triggered by activated oncoproteins.
Topics: Animals; Carrier Proteins; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cell Line, Tumor; Cyclin-Dependent Kinases; DNA Damage; HEK293 Cells; Humans; Hydroxyurea; Mice; Oncogene Proteins; Protein Kinases; S Phase; Signal Transduction; Thymidine | 2012 |
The effect of the diterpene 5-epi-icetexone on the cell cycle of Trypanosoma cruzi.
Topics: Cell Cycle; Chagas Disease; Diterpenes; Humans; Hydroxyurea; Thymidine; Time Factors; Trypanosoma cruzi | 2012 |
Stimulation of in vivo nuclear transport dynamics of actin and its co-factors IQGAP1 and Rac1 in response to DNA replication stress.
Topics: Actins; Active Transport, Cell Nucleus; Blotting, Western; Cell Nucleus; DNA Repair; DNA Replication; Fluorescence Recovery After Photobleaching; Humans; Hydroxyurea; Immunoprecipitation; Protein Binding; Protein Transport; rac1 GTP-Binding Protein; ras GTPase-Activating Proteins; RNA, Small Interfering; Signal Transduction; Thymidine | 2013 |
Amphiphilic lipid derivatives of 3'-hydroxyurea-deoxythymidine: preparation, properties, molecular self-assembly, simulation and in vitro anticancer activity.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Humans; Hydroxyurea; In Vitro Techniques; Nanostructures; Thymidine; Zidovudine | 2014 |