thymidine has been researched along with ganciclovir in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (27.03) | 18.7374 |
| 1990's | 12 (32.43) | 18.2507 |
| 2000's | 13 (35.14) | 29.6817 |
| 2010's | 2 (5.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jeffrey, GA; Martin, JC; Matthews, TR; McGee, DP; Smee, DF; Tippie, MA; Verheyden, JP | 1 |
| Clercq, ED; Folkers, G; Marquez, VE; Russ, P; Scapozza, L; Schelling, P | 1 |
| Black, DH; Eberle, R; Focher, F; Gambino, JJ; Lossani, A; Maioli, A; Medveczky, M; Medveczky, P; Shugar, D; Spadari, S; Verri, A; Wright, GE | 1 |
| Claessens, F; Dehaen, W; Helsen, C; Karypidou, K; Pannecouque, C; Persoons, L; Quevedo, MA; Ribone, SR | 1 |
| Baba, M; De Clercq, E; Konno, K; Shigeta, S; Yokota, T | 1 |
| Bryson, YJ | 1 |
| Alkan, HM; Khoobehi, B; Mani, H; Peyman, GA; Schulman, JA; Tawakol, ME | 1 |
| Coen, DM; Fleming, HE; Leslie, LK; Retondo, MJ | 1 |
| Bubley, G; Crumpacker, C; Oliver, S | 1 |
| Cantrill, H; Henry, K; Kish, MA | 1 |
| Blum, MR; de Miranda, P; Gordon, SM; Jacobson, MA; Mills, J; Volberding, P | 1 |
| Carlisle, R; Sommadossi, JP | 1 |
| Cockerill, FR; Hermans, PE | 1 |
| Crumpacker, CS; Field, AK; Livelli, TJ; Perry, HC; Tocci, MJ | 1 |
| Brown, DG; Davies, A; Melitz, C; Rizkallah, PJ; Sanderson, MR; Sandhu, G; Summers, WC; Visse, R | 1 |
| Caruso, M; Klatzmann, D; Loubière, L; Maury, S; Onclercq, R; Salomon, B | 1 |
| Breakefield, XO; Davidson, BL; Hughes, TL; Roessler, BJ; Shewach, DS; Zerbe, LK | 1 |
| Andrei, G; Balzarini, J; De Clercq, E; Helsberg, M; Jähne, G; Neyts, J; Snoeck, R; Winkler, I | 1 |
| Buckner, FS; Van Voorhis, WC; Wilson, AJ | 1 |
| Horvath, E; Lund, T; Medveczky, MM; Medveczky, PG | 1 |
| Gaudio, AC; Richards, WG; Takahata, Y | 1 |
| Davidson, BL; Rubsam, LZ; Shewach, DS | 1 |
| Radke, JR; White, MW | 1 |
| Altmann, A; Bellemann, ME; Brix, G; Doll, J; Gerlach, L; Haberkorn, U; Morr, I; Trojan, H; van Kaick, G | 1 |
| Drake, RR; Gilbert, KM; Hinds, TA; Wilbert, TN | 1 |
| Altmann, A; Haberkorn, U; Henze, M; Jiang, S; Kamencic, H; Kinscherf, R; Metz, J; Morr, I; Traut, U | 1 |
| Agbaria, R; Ford, H; Huleihel, M; Johns, DG; Konson, A; Manor, E; Marquez, VE; Zalah, L | 1 |
| Altmann, A; Haberkorn, U | 1 |
| Majumdar, S; Mitra, AK; Pal, D; Tirucherai, GS | 1 |
| Johansson, M; Karlsson, A; Lundberg, M; Zheng, X | 1 |
| Claus, MT; Johner, R; Marquez, VE; Scapozza, L; Schelling, P; Schulz, GE | 1 |
| Bae, PK; Chung, IK; Kim, HS; Kim, JH; Lee, CK; Paik, SG | 1 |
| Agbaria, R; Cohen, S; Dvir-Ginzberg, M; Konson, A | 1 |
| Balzarini, J; Camarasa, MJ; Familiar, O; Gago, F; Hernandez, AI; Karlsson, A; Negri, A; Pérez-Pérez, MJ; Rodríguez-Barrios, F | 1 |
| Field, HJ; Hussein, IT; Miguel, RN; Tiley, LS | 1 |
| Balzarini, J; Jasamai, M; Simons, C | 1 |
| Razonable, RR | 1 |
3 review(s) available for thymidine and ganciclovir
| Article | Year |
|---|---|
Promising new antiviral drugs.
Topics: Acyclovir; Animals; Antiviral Agents; Bromodeoxyuridine; Cytomegalovirus Infections; Foscarnet; Ganciclovir; Herpes Simplex; Herpes Zoster; Humans; Interferons; Phosphonoacetic Acid; Ribavirin; Thymidine; Zidovudine | 1988 |
Imaging methods in gene therapy of cancer.
Topics: Animals; Ganciclovir; Gene Transfer Techniques; Genes, Reporter; Genetic Therapy; Genetic Vectors; Humans; Iodides; Magnetic Resonance Imaging; Neoplasms; Oligonucleotides, Antisense; Simplexvirus; Thymidine; Thymidine Kinase; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon; Tumor Cells, Cultured | 2001 |
Antiviral drugs for viruses other than human immunodeficiency virus.
Topics: Acyclovir; Adenine; Amantadine; Antiviral Agents; Comorbidity; Drug Therapy, Combination; Foscarnet; Ganciclovir; Guanine; Hepatitis; Hepatitis B, Chronic; Hepatitis C; Herpesviridae Infections; HIV Infections; Humans; Influenza, Human; Interferons; Lamivudine; Nucleosides; Oligopeptides; Organophosphonates; Oseltamivir; Proline; Protease Inhibitors; Pyrimidinones; Ribavirin; Telbivudine; Thymidine; Valacyclovir; Valganciclovir; Valine; Virus Replication; Zanamivir | 2011 |
34 other study(ies) available for thymidine and ganciclovir
| Article | Year |
|---|---|
Acyclic analogues of 2'-deoxynucleosides related to 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine as potential antiviral agents.
Topics: Acyclovir; Animals; Antiviral Agents; Female; Ganciclovir; Herpes Simplex; Mice; Phosphorylation; Structure-Activity Relationship; Thymidine Kinase | 1985 |
Synthesis and biological evaluation of 5-substituted derivatives of the potent antiherpes agent (north)-methanocarbathymine.
Topics: Antiviral Agents; Cell Division; Cell Line; Cell Line, Tumor; Herpesviridae; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Humans; Kinetics; Molecular Conformation; Poxviridae; Pyrimidine Nucleosides; Structure-Activity Relationship; Thymidine Kinase; Thymine; Vaccinia virus; Viral Plaque Assay | 2003 |
Sensitivity of monkey B virus (Cercopithecine herpesvirus 1) to antiviral drugs: role of thymidine kinase in antiviral activities of substrate analogs and acyclonucleosides.
Topics: Acyclovir; Amino Acid Sequence; Animals; Antiviral Agents; Chlorocebus aethiops; Deoxyuridine; Enzyme Inhibitors; Guanine; Herpesvirus 1, Cercopithecine; Microbial Sensitivity Tests; Molecular Sequence Data; Nucleosides; Phosphorylation; Substrate Specificity; Thymidine; Thymidine Kinase; Vero Cells | 2007 |
Synthesis, biological evaluation and molecular modeling of a novel series of fused 1,2,3-triazoles as potential anti-coronavirus agents.
Topics: Antiviral Agents; Catalytic Domain; Cell Line, Tumor; Coronavirus; Coronavirus 3C Proteases; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Protein Binding; Structure-Activity Relationship; Triazoles; Viral Proteins | 2018 |
Comparative inhibitory effects of nucleoside analogues on different clinical isolates of human cytomegalovirus in vitro.
Topics: Adenine; Adenosine; Antiviral Agents; Cell Line; Cidofovir; Cytidine; Cytomegalovirus; Cytosine; Ganciclovir; Guanosine; Humans; Nucleosides; Organophosphonates; Organophosphorus Compounds; Thymidine | 1991 |
Toxicity and clearance of a combination of liposome-encapsulated ganciclovir and trifluridine.
Topics: Animals; Chromatography, High Pressure Liquid; Drug Carriers; Drug Combinations; Eye Enucleation; Ganciclovir; Injections; Liposomes; Rabbits; Thymidine; Time Factors; Trifluridine; Vitreous Body | 1989 |
Sensitivity of arabinosyladenine-resistant mutants of herpes simplex virus to other antiviral drugs and mapping of drug hypersensitivity mutations to the DNA polymerase locus.
Topics: Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Arabinonucleosides; Bromodeoxyuridine; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Genes, Viral; Idoxuridine; Mutation; Phosphonoacetic Acid; Simplexvirus; Thymidine; Vidarabine | 1985 |
Inhibition of HSV-transformed murine cells by nucleoside analogs, 2'-NDG and 2'-nor-cGMP: mechanisms of inhibition and reversal by exogenous nucleosides.
Topics: Acyclovir; Animals; Cell Division; Cell Line; Cell Survival; Cell Transformation, Viral; Cyclic GMP; Deoxycytidine; Deoxyguanosine; Ganciclovir; Guanine; Mice; Organophosphorus Compounds; Simplexvirus; Thymidine; Thymidine Kinase | 1985 |
Intravitreous ganciclovir for patients receiving zidovudine.
Topics: Acyclovir; Adult; Antiviral Agents; Cytomegalovirus Infections; Ganciclovir; Humans; Injections; Male; Retinitis; Thymidine; Vitreous Body; Zidovudine | 1987 |
Prolonged pancytopenia due to combined ganciclovir and zidovudine therapy.
Topics: Acyclovir; Antiviral Agents; Drug Therapy, Combination; Ganciclovir; Humans; Male; Middle Aged; Pancytopenia; Thymidine; Zidovudine | 1988 |
Toxicity of 3'-azido-3'-deoxythymidine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine for normal human hematopoietic progenitor cells in vitro.
Topics: Acyclovir; Antiviral Agents; Cells, Cultured; Dose-Response Relationship, Drug; Ganciclovir; Hematopoietic Stem Cells; Humans; Thymidine; Zidovudine | 1987 |
Antiviral agents.
Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Amantadine; Antiviral Agents; Ganciclovir; Herpes Simplex; Humans; Idoxuridine; Influenza A virus; Influenza, Human; Ribavirin; Rimantadine; Thymidine; Vidarabine; Viruses; Zidovudine | 1987 |
Effects of the nucleoside analog 2'-nor-2'-deoxyguanosine on human cytomegalovirus replication.
Topics: Acyclovir; Antiviral Agents; Cell Line; Cells, Cultured; Cytomegalovirus; DNA; DNA, Viral; Embryo, Mammalian; Ganciclovir; Humans; Lung; Thymidine; Time Factors; Virus Replication | 1984 |
Crystal structures of the thymidine kinase from herpes simplex virus type-1 in complex with deoxythymidine and ganciclovir.
Topics: Adenylate Kinase; Binding Sites; Crystallography, X-Ray; Cytosol; Ganciclovir; Herpesvirus 1, Human; Models, Molecular; Nucleosides; Nucleotides; Protein Conformation; Thymidine; Thymidine Kinase | 1995 |
A truncated herpes simplex virus thymidine kinase phosphorylates thymidine and nucleoside analogs and does not cause sterility in transgenic mice.
Topics: Animals; Base Sequence; Dendritic Cells; Fertility; Ganciclovir; Herpesvirus 1, Human; Infertility, Male; L Cells; Male; Methylation; Mice; Mice, Transgenic; Molecular Sequence Data; Phosphorylation; RNA, Messenger; Sequence Deletion; Testis; Thymidine; Thymidine Kinase; Transcription, Genetic | 1995 |
Enhanced cytotoxicity of antiviral drugs mediated by adenovirus directed transfer of the herpes simplex virus thymidine kinase gene in rat glioma cells.
Topics: Acyclovir; Adenoviruses, Human; Animals; Arabinonucleosides; Avian Sarcoma Viruses; Brain Neoplasms; Drug Resistance; Ganciclovir; Genes, Viral; Genetic Vectors; Glioma; Promoter Regions, Genetic; Rats; Recombinant Fusion Proteins; Simplexvirus; Thymidine; Thymidine Kinase; Transfection; Tumor Cells, Cultured | 1994 |
The N-7-substituted acyclic nucleoside analog 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine is a potent and selective inhibitor of herpesvirus replication.
Topics: Animals; Antiviral Agents; Cells, Cultured; DNA, Viral; Ganciclovir; Herpesviridae; Humans; Mice; Mice, Inbred C3H; Purines; Thymidine; Thymidine Kinase; Virus Replication | 1994 |
Trypanosoma cruzi: use of herpes simplex virus-thymidine kinase as a negative selectable marker.
Topics: 3T3 Cells; Animals; Antiviral Agents; Blotting, Southern; Chagas Disease; Cloning, Molecular; Drug Resistance; Female; Ganciclovir; Gene Expression Regulation, Enzymologic; Genetic Markers; Mice; Parasitemia; Phosphotransferases (Alcohol Group Acceptor); Recombinant Fusion Proteins; Simplexvirus; Thymidine; Thymidine Kinase; Transfection; Trypanosoma cruzi | 1997 |
In vitro antiviral drug sensitivity of the Kaposi's sarcoma-associated herpesvirus.
Topics: Acyclovir; Antiviral Agents; Carcinogens; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; DNA, Viral; Foscarnet; Ganciclovir; Herpesvirus 8, Human; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Phorbol 12,13-Dibutyrate; Sarcoma, Kaposi; Thymidine; Tumor Cells, Cultured; Virus Latency | 1997 |
Prediction of the binding mode of N2-phenylguanine derivative inhibitors to herpes simplex virus type 1 thymidine kinase.
Topics: Amino Acid Sequence; Antiviral Agents; Binding Sites; Binding, Competitive; Computer Simulation; Enzyme Inhibitors; Ganciclovir; Guanine; Herpesvirus 1, Human; Humans; Models, Molecular; Phosphorylation; Protein Conformation; Sequence Homology, Amino Acid; Species Specificity; Thermodynamics; Thymidine; Thymidine Kinase | 1998 |
Superior cytotoxicity with ganciclovir compared with acyclovir and 1-beta-D-arabinofuranosylthymine in herpes simplex virus-thymidine kinase-expressing cells: a novel paradigm for cell killing.
Topics: Acyclovir; Antineoplastic Agents; Apoptosis; Arabinonucleosides; Cell Cycle; DNA; Ganciclovir; Humans; Phosphorylation; Simplexvirus; Thymidine; Thymidine Kinase | 1998 |
A cell cycle model for the tachyzoite of Toxoplasma gondii using the Herpes simplex virus thymidine kinase.
Topics: Animals; Antimetabolites; Bromouracil; Cell Cycle; Chloramphenicol O-Acetyltransferase; DNA, Protozoan; Electroporation; Flow Cytometry; G1 Phase; G2 Phase; Ganciclovir; Genetic Vectors; Herpesvirus 2, Human; Mitosis; Recombinant Fusion Proteins; S Phase; Selection, Genetic; Thymidine; Thymidine Kinase; Toxoplasma; Uridine | 1998 |
Uncoupling of 2-fluoro-2-deoxyglucose transport and phosphorylation in rat hepatoma during gene therapy with HSV thymidine kinase.
Topics: Animals; Antimetabolites; Biological Transport; Fluorodeoxyglucose F18; Ganciclovir; Genetic Therapy; Liver Neoplasms, Experimental; Phosphorylation; Rats; Thymidine; Thymidine Kinase; Tomography, Emission-Computed | 1998 |
Differential ganciclovir-mediated cell killing by glutamine 125 mutants of herpes simplex virus type 1 thymidine kinase.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Caspases; Cell Cycle; Cell Line; Deoxycytidine; Ganciclovir; Genetic Therapy; Glutamine; Herpesvirus 1, Human; Mice; Mutation; Thymidine; Thymidine Kinase | 1999 |
Glucose transport and apoptosis after gene therapy with HSV thymidine kinase.
Topics: 3-O-Methylglucose; Animals; Antiviral Agents; Apoptosis; Cytochalasin B; Excitatory Amino Acid Transporter 2; Fluorodeoxyglucose F18; Ganciclovir; Genetic Therapy; Glucose; Glucose Transporter Type 3; Immunohistochemistry; In Situ Nick-End Labeling; Liver Neoplasms, Experimental; Male; Monosaccharide Transport Proteins; Neoplasm Transplantation; Nerve Tissue Proteins; Radiopharmaceuticals; Rats; Rats, Inbred ACI; Simplexvirus; Thymidine; Thymidine Kinase; Tumor Cells, Cultured | 2001 |
Metabolic pathways of N-methanocarbathymidine, a novel antiviral agent, in native and herpes simplex virus type 1 infected Vero cells.
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Cytopathogenic Effect, Viral; Ganciclovir; Herpesvirus 1, Human; Phosphorylation; Polyphosphates; Thymidine; Vero Cells | 2002 |
Functional differences in nucleoside and nucleobase transporters expressed on the rabbit corneal epithelial cell line (SIRC) and isolated rabbit cornea.
Topics: Adenine; Animals; Biological Transport; Cornea; Epithelium, Corneal; Ganciclovir; Male; Membrane Transport Proteins; Nucleosides; Nucleotide Transport Proteins; Rabbits; Sodium; Thioinosine; Thymidine; Tritium | 2003 |
Lipid-mediated protein delivery of suicide nucleoside kinases.
Topics: Animals; Arabinonucleosides; Bone Neoplasms; Bromodeoxyuridine; Cell Line, Tumor; CHO Cells; Cricetinae; Drosophila melanogaster; Endocytosis; Ganciclovir; Herpesvirus 1, Human; Humans; Liposomes; Osteosarcoma; Phosphatidylethanolamines; Phosphotransferases (Alcohol Group Acceptor); Recombinant Proteins; Thymidine; Thymidine Kinase | 2003 |
Biochemical and structural characterization of (South)-methanocarbathymidine that specifically inhibits growth of herpes simplex virus type 1 thymidine kinase-transduced osteosarcoma cells.
Topics: Antiviral Agents; Binding Sites; Cell Division; Cell Line, Tumor; Crystallography, X-Ray; Dose-Response Relationship, Drug; Ganciclovir; Herpesvirus 1, Human; Humans; Inhibitory Concentration 50; Kinetics; Models, Chemical; Models, Molecular; Osteosarcoma; Phosphorylation; Protein Binding; Protein Conformation; Thymidine; Thymidine Kinase; Time Factors; Transfection | 2004 |
Intracellular uptake of thymidine and antiherpetic drugs for thymidine kinase-deficient mutants of herpes simplex virus type 1.
Topics: Acyclovir; Animals; Antiviral Agents; Cell Line, Tumor; Chlorocebus aethiops; DNA; DNA, Viral; Drug Resistance, Viral; Ganciclovir; Guanine; Herpesvirus 1, Human; Humans; Mutation; Substrate Specificity; Thymidine; Thymidine Kinase; Vero Cells | 2006 |
Entrapment of retroviral vector producer cells in three-dimensional alginate scaffolds for potential use in cancer gene therapy.
Topics: Alginates; Animals; Antiviral Agents; Cell Culture Techniques; Cells, Immobilized; Ganciclovir; Genetic Therapy; Genetic Vectors; Glucuronic Acid; Herpes Simplex; Hexuronic Acids; Mice; Neoplasms, Experimental; Retroviridae; Thymidine; Thymidine Kinase; Tumor Cells, Cultured | 2007 |
N1-substituted thymine derivatives as mitochondrial thymidine kinase (TK-2) inhibitors.
Topics: Adenosine Triphosphate; Animals; Antiviral Agents; Arabinonucleosides; Binding, Competitive; Cell Proliferation; Cell Survival; Drosophila melanogaster; Enzyme Inhibitors; Ganciclovir; Herpes Simplex; Herpesvirus 1, Human; Humans; Kinetics; Mitochondria; Models, Molecular; Molecular Conformation; Phosphorylation; Structure-Activity Relationship; Thymidine; Thymidine Kinase; Thymine | 2006 |
Substrate specificity and molecular modelling of the feline herpesvirus-1 thymidine kinase.
Topics: Acyclovir; Animals; Antiviral Agents; Cats; Cloning, Molecular; Ganciclovir; Guanine; Hydrogen Bonding; Models, Molecular; Mutagenesis, Site-Directed; Phosphorylation; Protein Conformation; Protein Structure, Secondary; Substrate Specificity; Thymidine; Thymidine Kinase; Varicellovirus | 2008 |
6-Azathymidine-4'-thionucleosides: synthesis and antiviral evaluation.
Topics: Acyclovir; Antiviral Agents; Bromodeoxyuridine; Ganciclovir; Magnetic Resonance Spectroscopy; Models, Molecular; Thionucleosides; Thymidine | 2008 |