Compounds > thymidine
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thymidine and fluorodeoxyuridylate

thymidine has been researched along with fluorodeoxyuridylate in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19907 (63.64)18.7374
1990's2 (18.18)18.2507
2000's2 (18.18)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Herdewijn, P; Munier-Lehmann, H; Pochet, S; Van Calenbergh, S; Van Rompaey, P; Vanheusden, V1
Danhauser, L; Rustum, YM; Wang, G1
Farquhar, D; Freed, JJ; Hampton, A1
Allegra, CJ; Baram, J; Chabner, BA; Fitzhugh, AL; Sholar, PW1
Myers, CE1
Mandel, HG1
Kimura, K; Tanaka, M; Yoshida, S1
Au, JL; Danhauser, L; Luccioni, C; Rustum, YM1
Csapó, Z; Keszler, G; Noordhuis, P; Peters, GJ; Sasvári-Székely, M; Smid, K; Staub, M1
Berger, SH; Steadman, DJ; Zapf, JW; Zhao, PS1
Antony, S; Gmeiner, WH; Kohlhagen, G; Liao, ZY; Pommier, Y; Sordet, O; Zhang, HL1

Reviews

3 review(s) available for thymidine and fluorodeoxyuridylate

ArticleYear
The pharmacology of the fluoropyrimidines.
    Pharmacological reviews, 1981, Volume: 33, Issue:1

    Topics: Animals; Chemical Phenomena; Chemistry; Deoxyuracil Nucleotides; Flucytosine; Fluorodeoxyuridylate; Fluorouracil; Fungi; Humans; Kinetics; RNA; Thymidine; Thymidylate Synthase

1981
The target cell determinants of the antitumor actions of 5-FU: does FU incorporation into RNA play a role?
    Cancer treatment reports, 1981, Volume: 65 Suppl 3

    Topics: Animals; DNA, Bacterial; DNA, Neoplasm; Fluorodeoxyuridylate; Fluorouracil; Mice; Neoplasms, Experimental; RNA, Bacterial; RNA, Neoplasm; Thymidine

1981
Determinants of response to antimetabolites and their modulation by normal purine and pyrimidine metabolites.
    Cancer treatment reports, 1981, Volume: 65 Suppl 3

    Topics: Animals; Antimetabolites, Antineoplastic; Cytarabine; DNA, Neoplasm; Fluorodeoxyuridylate; Fluorouracil; Humans; Leukemia L1210; Neoplasms; Neoplasms, Experimental; Thymidine; Thymidylate Synthase; Uridine

1981

Other Studies

8 other study(ies) available for thymidine and fluorodeoxyuridylate

ArticleYear
Thymidine and thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase.
    Bioorganic & medicinal chemistry letters, 2003, Sep-15, Volume: 13, Issue:18

    Topics: Antitubercular Agents; Enzyme Inhibitors; Inhibitory Concentration 50; Kinetics; Mycobacterium tuberculosis; Nucleoside-Phosphate Kinase; Structure-Activity Relationship; Thymidine; Thymine Nucleotides

2003
Selectivity of action of 5-FU: biochemical basis.
    Bulletin du cancer, 1979, Volume: 66, Issue:1

    Topics: Animals; Colonic Neoplasms; Drug Resistance; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Humans; Leukemia L1210; Mice; Mice, Inbred Strains; Rats; RNA, Neoplasm; Thymidine; Uridine

1979
Evidence for acyloxymethyl esters of pyrimidine 5'-deoxyribonucleotides as extracellular sources of active 5'-deoxyribonucleotides in cultured cells.
    Biochemical pharmacology, 1989, Oct-01, Volume: 38, Issue:19

    Topics: Animals; Blood Physiological Phenomena; Cells, Cultured; Deoxyuracil Nucleotides; Deoxyuridine; DNA; Esters; Fluorodeoxyuridylate; Fluorouracil; Mice; Thymidine; Thymidine Monophosphate

1989
Antifolate metabolism and sites of action: implications for the design of new antifolates.
    NCI monographs : a publication of the National Cancer Institute, 1987, Issue:5

    Topics: Fluorodeoxyuridylate; Folic Acid Antagonists; Humans; Purines; Thymidine; Thymidylate Synthase

1987
Enhancement of the incorporation of 5-fluorodeoxyuridylate into DNA of HL-60 cells by metabolic modulations.
    Cancer research, 1983, Volume: 43, Issue:11

    Topics: Cell Line; Deoxyuracil Nucleotides; DNA Replication; DNA, Neoplasm; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Humans; Kinetics; Leukemia, Myeloid, Acute; Methotrexate; Thymidine; Tritium

1983
Similar changes were induced by Cladribine and by gemcitabine, in the deoxypyrimidine salvage, during short-term treatments.
    Advances in experimental medicine and biology, 1998, Volume: 431

    Topics: Antimetabolites, Antineoplastic; Cell Line; Cladribine; DCMP Deaminase; Deoxycytidine; Deoxycytidine Kinase; Deoxyuracil Nucleotides; Enzyme Inhibitors; Fluorodeoxyuridylate; Gemcitabine; Humans; In Vitro Techniques; Kinetics; Lymphocytes; Palatine Tonsil; Thymidine; Thymidine Kinase

1998
Genetic complementation and resistance to 5-fluoro-2'-deoxyuridine in thymidine auxotrophs expressing a highly defective mutant of human thymidylate synthase.
    Biochemical pharmacology, 1999, Sep-15, Volume: 58, Issue:6

    Topics: Animals; Antimetabolites, Antineoplastic; Cell Division; Cell Line; Cricetinae; Cricetulus; Drug Resistance; Floxuridine; Fluorodeoxyuridylate; Genetic Complementation Test; Humans; Point Mutation; Thymidine; Thymidylate Synthase; Transfection

1999
A novel polypyrimidine antitumor agent FdUMP[10] induces thymineless death with topoisomerase I-DNA complexes.
    Cancer research, 2005, Jun-01, Volume: 65, Issue:11

    Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Death; DNA Damage; DNA Topoisomerases, Type I; DNA, Neoplasm; DNA, Single-Stranded; Drug Screening Assays, Antitumor; Fluorodeoxyuridylate; Fluorouracil; Leukemia P388; Mice; Quinazolines; Thiophenes; Thymidine; Thymidylate Synthase; Topoisomerase I Inhibitors

2005