Page last updated: 2024-08-17

thymidine and eflornithine

thymidine has been researched along with eflornithine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19908 (29.63)18.7374
1990's13 (48.15)18.2507
2000's3 (11.11)29.6817
2010's2 (7.41)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Hacker, AD1
Beyer, HS; Ellefson, M; Stanley, M; Zieve, L1
Benenati, SV; Fleck, JF; Frolik, CA; Hirsch, KS; Roth, BJ; Sledge, GW1
Johnson, LR; McCormack, SA; Viar, MJ; Wang, JY1
Castro, GA; Johnson, LR; Tsai, YH; Wang, JY1
Eshbaugh, WG; Forley, BG; Klitzman, B; Ritter, EF; Serafin, D1
Brzozowski, T; Dembiński, A; Konturek, PK; Konturek, SJ1
Newberne, PM; Sondergaard, D; Taylor, F1
Kortsaris, A; Kyriakidis, DA1
Bachrach, U; Shtorch, A1
Gallo, CJ; Herbst, EJ; Koza, RA1
Brady, AN; D'Arcy, JB; Li, LC; Smiler, KL; White, DM; Wright, ES1
Gilad, GM; Gilad, VH1
Bianchi, M; Donati, MB; Ghezzi, P; Poggi, A; Salmona, M; Vicenzi, E1
Griffin, JD; Kufe, DW; Larcom, P1
Argenzio, RA; Berschneider, HM; Brenner, DA; Chen, W; Kandil, HM; Rhoads, JM; Rippe, RA; Stiles, AD; Westwick, JK1
Carlos, AS; Klein, RF1
Thomas, T; Thomas, TJ1
Johnson, LR; Wang, JY1
Pennington, SN; Sandstrom, LP1
Bódi, J; Ghanem, G; Medzihradszky-Schweiger, H; Morandini, R; Nagy, L; Süli-Vargha, H1
Cho, CH; Koo, MW; Li, Y; Liu, ES; Matsui, H; Shin, VY; Wei, EQ; Ye, YN1
Bass, BL; Guo, X; Li, L; Liu, L; Rao, JN; Santora, R; Wang, JY1
Blanco, I; Danchev, N; Dot, J; Rodríguez-Alvarez, J1
Chen, Q; Gross, SS; Kopelovich, L; Lipkin, SM; Witherspoon, M1
Casero, RA1
Hyvönen, MT; Keinänen, TA; Khomutov, AR; Khomutov, M; Vepsäläinen, J1

Other Studies

27 other study(ies) available for thymidine and eflornithine

ArticleYear
Inhibition of deoxyribonucleic acid synthesis by difluoromethylornithine. Role of polyamine metabolism in monocrotaline-induced pulmonary hypertension.
    Biochemical pharmacology, 1992, Sep-01, Volume: 44, Issue:5

    Topics: Animals; Biogenic Polyamines; Blood Pressure; DNA; DNA Replication; Eflornithine; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Ornithine; Rats; Rats, Inbred Strains; Thymidine

1992
Inhibition of increases in ornithine decarboxylase and putrescine has no effect on rat liver regeneration.
    The American journal of physiology, 1992, Volume: 262, Issue:4 Pt 1

    Topics: Animals; Eflornithine; Hepatectomy; Leucine; Liver; Liver Regeneration; Male; Mitotic Index; Ornithine Decarboxylase Inhibitors; Protein Biosynthesis; Putrescine; Rats; Rats, Inbred Strains; Thymidine; Time Factors

1992
Binding of insulin-like growth factors to Tera-2 human embryonal carcinoma cells during differentiation.
    Cancer research, 1991, Aug-15, Volume: 51, Issue:16

    Topics: Binding Sites; Binding, Competitive; Cell Differentiation; Cell Division; Cell Line; DNA Replication; Eflornithine; Humans; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Kinetics; Lewis X Antigen; Recombinant Proteins; Teratoma; Thymidine

1991
Stimulation of proximal small intestinal mucosal growth by luminal polyamines.
    The American journal of physiology, 1991, Volume: 261, Issue:3 Pt 1

    Topics: Animals; Cell Line; DNA; DNA Replication; Duodenum; Eflornithine; Intestinal Mucosa; Jejunum; Kinetics; Male; Ornithine Decarboxylase; Proteins; Rats; Rats, Inbred Strains; RNA; Spermidine; Spermine; Thymidine; Tritium

1991
Mucosal ornithine decarboxylase, polyamines, and hyperplasia in infected intestine.
    The American journal of physiology, 1991, Volume: 260, Issue:1 Pt 1

    Topics: Animals; Chromatography, High Pressure Liquid; DNA Replication; Duodenum; Eflornithine; Hyperplasia; Ileum; Intestinal Mucosa; Intestine, Small; Jejunum; Male; Ornithine Decarboxylase; Peroxidase; Polyamines; Rats; Rats, Inbred Strains; Reference Values; Thymidine; Trichinellosis

1991
Stimulation of DNA synthesis in human epidermis by UVB radiation and its inhibition by difluoromethylornithine.
    Plastic and reconstructive surgery, 1990, Volume: 85, Issue:4

    Topics: Aged; Animals; DNA; Eflornithine; Epidermis; Female; Humans; Mice; Mice, Nude; Middle Aged; Skin; Skin Transplantation; Thymidine; Transplantation, Heterologous; Ultraviolet Rays

1990
Role of epidermal growth factor, prostaglandin, and sulfhydryls in stress-induced gastric lesions.
    Gastroenterology, 1990, Volume: 99, Issue:6

    Topics: 16,16-Dimethylprostaglandin E2; Animals; DNA; Eflornithine; Epidermal Growth Factor; Ethylmaleimide; Gastric Mucosa; Glutathione; Male; Ornithine Decarboxylase; Prostaglandins; Rats; Rats, Inbred Strains; Salivary Glands; Stomach Ulcer; Stress, Physiological; Sulfhydryl Compounds; Thymidine

1990
Effects of the irreversible ornithine decarboxylase inhibitor, alpha-difluoromethylornithine, aflatoxin B1, and choline deficiency on hepatocarcinogenesis.
    Toxicologic pathology, 1985, Volume: 13, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; alpha-Fetoproteins; Animals; Choline Deficiency; DNA; Eflornithine; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Male; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Rats; Rats, Inbred F344; Thymidine

1985
Effects of human interferon and alpha-difluoromethylornithine on T47D cells.
    Journal of interferon research, 1986, Volume: 6, Issue:5

    Topics: Breast Neoplasms; Cell Line; DNA; Drug Synergism; Eflornithine; Humans; Interferons; Ornithine Decarboxylase; Thymidine; Tritium

1986
Formation of cadaverine as an effect of alpha-difluoromethylornithine on chick embryo fibroblasts transformed by rous sarcoma virus.
    Cancer research, 1985, Volume: 45, Issue:5

    Topics: Animals; Avian Sarcoma Viruses; Cadaverine; Cell Transformation, Neoplastic; Cell Transformation, Viral; Chick Embryo; Diamines; Eflornithine; Fibroblasts; Ornithine; Polyamines; Proteins; Thymidine

1985
Polyamines and HeLa-cell DNA replication.
    The Biochemical journal, 1986, Aug-15, Volume: 238, Issue:1

    Topics: DNA Replication; Eflornithine; HeLa Cells; Humans; Interphase; Polyamines; Putrescine; Spermidine; Spermine; Thymidine

1986
DNA synthesis in pulmonary alveolar macrophages and type II cells: effects of ozone exposure and treatment with alpha-difluoromethylornithine.
    Journal of toxicology and environmental health, 1987, Volume: 21, Issue:1-2

    Topics: Animals; DNA Replication; Eflornithine; Lung; Macrophages; Male; Mitotic Index; Ozone; Rats; Rats, Inbred F344; Thymidine

1987
Polyamines affect growth of cultured rat cerebellar neurons in different sera.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 1986, Volume: 4, Issue:3

    Topics: Animals; Blood Proteins; Cattle; Cell Division; Cell Survival; Cerebellum; Eflornithine; Guanidines; Humans; Polyamines; Rats; Species Specificity; Spermine; Thymidine

1986
Platelet derived growth factor induces ornithine decarboxylase activity in NIH 3T3 cells.
    Biochemical and biophysical research communications, 1985, Mar-29, Volume: 127, Issue:3

    Topics: Animals; Cell Line; Eflornithine; Enzyme Induction; Mice; Mitosis; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Platelet-Derived Growth Factor; Thymidine

1985
TPA induces differentiation of purified human myeloblasts in the absence of proliferation.
    Experimental hematology, 1985, Volume: 13, Issue:10

    Topics: Bone Marrow; Bone Marrow Cells; Cell Differentiation; Cell Division; Colony-Stimulating Factors; DNA Replication; Eflornithine; Hematopoietic Stem Cells; Humans; Ornithine; Phorbols; Rosette Formation; Tetradecanoylphorbol Acetate; Thymidine; Tritium

1985
L-glutamine and L-asparagine stimulate ODC activity and proliferation in a porcine jejunal enterocyte line.
    The American journal of physiology, 1995, Volume: 269, Issue:4 Pt 1

    Topics: Aminooxyacetic Acid; Animals; Asparagine; Cell Division; Cell Line; Drug Synergism; Eflornithine; Enzyme Activation; Glutamine; Jejunum; Ornithine Decarboxylase; Protein Kinase C; Proto-Oncogene Proteins c-jun; RNA, Messenger; Sodium-Hydrogen Exchangers; Swine; Thymidine; Transaminases

1995
Inhibition of osteoblastic cell proliferation and ornithine decarboxylase activity by ethanol.
    Endocrinology, 1995, Volume: 136, Issue:8

    Topics: Animals; Cell Division; Eflornithine; Ethanol; Ornithine Decarboxylase Inhibitors; Osteoblasts; Polyamines; Rats; Thymidine; Tumor Cells, Cultured

1995
Estradiol control of ornithine decarboxylase mRNA, enzyme activity, and polyamine levels in MCF-7 breast cancer cells: therapeutic implications.
    Breast cancer research and treatment, 1994, Volume: 29, Issue:2

    Topics: Breast Neoplasms; Cell Division; Cell Line; Eflornithine; Estradiol; Female; Flow Cytometry; G1 Phase; Gene Expression; Humans; Kinetics; Ornithine Decarboxylase; Polyamines; Putrescine; RNA, Messenger; Spermidine; Spermine; Structure-Activity Relationship; Thymidine; Time Factors; Tumor Cells, Cultured

1994
Expression of protooncogenes c-fos and c-myc in healing of gastric mucosal stress ulcers.
    The American journal of physiology, 1994, Volume: 266, Issue:5 Pt 1

    Topics: Animals; Blotting, Northern; Blotting, Western; DNA; DNA Probes; Eflornithine; Enzyme Induction; Gastric Mucosa; Gene Expression; Genes, fos; Genes, myc; Immersion; Kinetics; Male; Ornithine Decarboxylase; Parietal Cells, Gastric; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; Putrescine; Rats; Rats, Sprague-Dawley; Restraint, Physical; RNA, Messenger; Spermidine; Spermine; Stomach Ulcer; Stress, Psychological; Thymidine; Time Factors; Wound Healing

1994
Embryonic growth inhibition induced by cocaine is associated with the suppression of ornithine decarboxylase activity.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1993, Volume: 202, Issue:4

    Topics: Animals; Cell Division; Chick Embryo; Cocaine; Dose-Response Relationship, Drug; Eflornithine; Insulin; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Putrescine; Thymidine; Time Factors

1993
In vitro cytotoxic effect of difluoromethylomithine increased nonspecifically by peptide coupling.
    Journal of pharmaceutical sciences, 1997, Volume: 86, Issue:9

    Topics: Antineoplastic Agents; Eflornithine; Humans; Hydrolysis; Melanocyte-Stimulating Hormones; Melanoma, Experimental; Peptides; Receptors, Pituitary Hormone; Thymidine; Tumor Cells, Cultured

1997
A mechanistic study of proliferation induced by Angelica sinensis in a normal gastric epithelial cell line.
    Biochemical pharmacology, 2001, Jun-01, Volume: 61, Issue:11

    Topics: Angelica sinensis; Animals; Apiaceae; Cell Division; Cells, Cultured; Disease Models, Animal; DNA; Drugs, Chinese Herbal; Eflornithine; Enzyme Inhibitors; Intestinal Mucosa; Ornithine Decarboxylase; Plant Extracts; Proto-Oncogene Proteins c-myc; Rats; Rats, Wistar; Stomach Ulcer; Thymidine; Tritium; Wound Healing

2001
Polyamine depletion stabilizes p53 resulting in inhibition of normal intestinal epithelial cell proliferation.
    American journal of physiology. Cell physiology, 2001, Volume: 281, Issue:3

    Topics: Animals; Cell Division; Cell Line; Cycloheximide; DNA; Eflornithine; Gene Expression Regulation; Genes, p53; Intestinal Mucosa; Intestine, Small; Kinetics; Male; Methionine; Models, Biological; Oligodeoxyribonucleotides, Antisense; Ornithine Decarboxylase; Polyamines; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thymidine; Transcription, Genetic; Tumor Suppressor Protein p53

2001
Polyamine uptake is necessary for a normal biochemical maturation of astrocytes in culture.
    Neuroreport, 2002, Jun-12, Volume: 13, Issue:8

    Topics: Animals; Astrocytes; Biogenic Polyamines; Cell Differentiation; Cell Division; Cells, Cultured; Cerebellum; DNA; Down-Regulation; Eflornithine; Enzyme Inhibitors; Glutamate-Ammonia Ligase; Mice; Mitoguazone; Ornithine Decarboxylase; Putrescine; Spermidine; Spermine; Thymidine; Up-Regulation

2002
Unbiased metabolite profiling indicates that a diminished thymidine pool is the underlying mechanism of colon cancer chemoprevention by alpha-difluoromethylornithine.
    Cancer discovery, 2013, Volume: 3, Issue:9

    Topics: Animals; Cell Line, Tumor; Chemoprevention; Colorectal Neoplasms; Eflornithine; Enzyme Inhibitors; HT29 Cells; Humans; Mice; Ornithine Decarboxylase Inhibitors; S-Adenosylmethionine; Thymidine

2013
Say what? The activity of the polyamine biosynthesis inhibitor difluoromethylornithine in chemoprevention is a result of reduced thymidine pools?
    Cancer discovery, 2013, Volume: 3, Issue:9

    Topics: Animals; Colorectal Neoplasms; Eflornithine; Enzyme Inhibitors; Humans; Thymidine

2013
α-Difluoromethylornithine-Induced Cytostasis is Reversed by Exogenous Polyamines, Not by Thymidine Supplementation.
    Biomolecules, 2021, 05-10, Volume: 11, Issue:5

    Topics: Animals; Cells, Cultured; Cytostatic Agents; Eflornithine; Humans; Mice; Neoplasms; Ornithine Decarboxylase Inhibitors; Polyamines; Thymidine

2021