thymidine has been researched along with deoxyuridine in 475 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 362 (76.21) | 18.7374 |
| 1990's | 37 (7.79) | 18.2507 |
| 2000's | 36 (7.58) | 29.6817 |
| 2010's | 33 (6.95) | 24.3611 |
| 2020's | 7 (1.47) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, MS; Prusoff, WH; Schinazi, RF | 1 |
| Arcamone, F; Capobianco, M; Carcuro, A; Ciarrocchi, G; Colonna, F; Focher, F; Iotti, S; Maga, G; Manservigi, R; Spadari, S | 1 |
| Knaus, EE; Mercer, JR; Wiebe, LI; Xu, LH | 1 |
| Knaus, EE; Mercer, JR; Wiebe, LI | 1 |
| Meyer, RB; Nakayama, C; Saneyoshi, M; Santi, DV; Ueda, T; Wataya, Y | 1 |
| de Julián-Ortiz, JV; Gálvez, J; García-Domenech, R; Gimeno-Cardona, C; Muñoz-Collado, C | 1 |
| Anisuzzaman, AK; Blue, TE; Eriksson, S; Ikeda, S; Ives, DH; Ji, W; Lunato, AJ; Rong, FG; Soloway, AH; Tjarks, W; Wang, J; Woollard, JE | 1 |
| Kim, DH; Kim, KN; Kwon, HJ; Lee, J; Yoo, JS | 1 |
| Harano, A; Hatano, A; Nakagomi, Y; Naramoto, Y; Takigawa, Y; Toda, K; Yamada, H | 1 |
| Agrawal, B; Kumar, R; Mak, M; Srivastav, NC; Tyrrell, DL | 1 |
| Dundaroff, S; Falke, D; Just, I | 1 |
| Schreiber, C; Waxman, S | 1 |
| Hackstadt, T; Mallavia, LP | 1 |
| Clough, DW; Parkhurst, JR; Wigdahl, BL | 1 |
| Nelson, DJ; Pavan-Langston, D | 1 |
| Abbott, MT; Hsu, CA; Shaffer, PM | 1 |
| Mathews, CK | 1 |
| Roberts, D; Warmath, EV | 1 |
| Pfefferkorn, ER; Pfefferkorn, LC | 2 |
| Chanarin, I; Stafford, DM; Taguchi, H | 1 |
| Lindner, C; Volm, M | 1 |
| Biermann, WA; Haurani, FI; Kardinal, CG | 1 |
| Bowen, D; Diasio, RB; Goldman, ID | 1 |
| Baker, PN; Bradshaw, TK; Burke, DC; Morser, J | 1 |
| Parsons, PG; Smellie, SG | 1 |
| Boynton, AL; MacManus, JP; Rixon, RH; Whitfield, JF | 1 |
| Boynton, AL; MacManus, JP; Rixon, RH; Swierenga, S; Whitfield, JF; Youdale, T | 1 |
| Crumley, J; Wilkinson, DS | 1 |
| Hopkins, HA; Wakefield, JA | 1 |
| Bose, R; Yamada, EW | 1 |
| De Clercq, E; Descamps, J; Mertes, MP; Schmidt, CL | 1 |
| Bilski-Pasquier, G; Marquet, J; Sultan, C; Zittoun, J; Zittoun, R | 1 |
| Lietman, PS; Rogers, HJ | 1 |
| Ganeshaguru, K; Hoffbrand, AV | 1 |
| Sauer, H; Schalhorn, A; Wilmanns, W | 2 |
| Halpern, A; Stöcklin, G | 1 |
| Aus, HM; Harms, H; Haucke, M; Kellerer, A; Korr, H; Maurer-Schultze, B; Rüter, A; ter Meulen, V | 1 |
| Chawla, RR; Hampton, A; Kappler, F | 1 |
| Van Der Weyden, MB | 1 |
| Lewis, HL; Muhleman, DR; Ward, JF | 1 |
| Davidson, RL; Kaufman, ER | 1 |
| Marquet, J; Zittoun, J; Zittoun, R | 1 |
| Cacace, F; Stöcklin, G | 1 |
| Kaufmann, M; Kubli, F; Reus, W; Volm, M; von Fournier, D | 1 |
| De Clercq, E; Descamps, J; Huang, GF; Torrence, PF | 1 |
| Frati, L; Menconi, E; Neri, M; Sorci, V | 1 |
| Chanarin, I; Taguchi, H | 1 |
| Betzler, M; Breitig, D; Geier, G; Herfarth, C; Schlag, P; Veser, J | 1 |
| Friedberg, EC; Ganesan, AK; Minton, K | 1 |
| Fung, WP; Yang, KH; Zaharko, DS | 1 |
| Sauer, H; Wilmanns, W | 1 |
| Chanarin, I; Laundy, M; Reid, C; Reynolds, EH; Taguchi, H | 1 |
| Balint, RF; Gauri, KK; Silagi, S | 1 |
| Hummel, H; Mattern, J; Volm, M | 1 |
| Albert, DM; Bhatt, PN; Cykiert, RC; Lahav, M; Lin, TS; Prusoff, WH; Reid, TW; Ward, DC; Ward, RE | 1 |
| Bolewska, K; Plesiewicz, E; Stepień, E; Wierzchowski, KL | 1 |
| Curt, GA; Kramer, RA; Parker, LM; Rosowsky, A; Tattersall, MH; Tobias, JS | 1 |
| Blakley, RL; Ho, YK; Hoffmann, CC; Thompson, JS | 1 |
| Bechynĕ, M; Buric, L; Dientsbier, Z; Foltýnová, V; Kovaríková, H; Mostecký, H | 1 |
| Badcock, J; James, WP; Tomkins, AM | 1 |
| Hryniuk, WM | 1 |
| Aradi, J; Bardos, TJ; Ho, YK; Kalman, TI | 1 |
| Firkin, BG; Schwarz, MA | 1 |
| Håkansson, L | 1 |
| Sprent, J | 1 |
| Greenberg, ML; Waxman, S | 1 |
| Brun, G; Goodgame, DM; Skapski, AC | 1 |
| McCullough, JL; Weinstein, GD | 1 |
| Buric, L; Dienstbier, Z | 1 |
| Bäck, R; Linna, TJ | 1 |
| Bärwolff, D; Langen, P | 1 |
| Cheng, FW; Shane, B; Stokstad, EL | 1 |
| Ratliff, RL; Walters, RA | 1 |
| Cohen, AM | 1 |
| Chabner, BA; Myers, CE; Young, RC | 1 |
| Drab, EA; Linder, JS; Rubin, DB; Sabesin, SM; Sharon, P; Weidman, SW | 1 |
| Bhimani, R; Frenkel, K; Patel, U | 1 |
| Birks, EM; Lin, TS; Pivazyan, AD; Prusoff, WH; Wood, TG | 1 |
| Grem, JL | 1 |
| Montgomery, JA; Riordan, JM; Secrist, JA; Tiwari, KN | 1 |
| Stobetskiĭ, VI | 1 |
| Joly, JM; Williams, WM | 1 |
| Brumley, J; Hayman, RJ; Rose, IS; van der Weyden, MB | 1 |
| Cravo, ML; Mason, JB; Rosenberg, IH; Selhub, J | 1 |
| Alarcòn, GS; Baggott, JE; Everson, MP; Hardin, JM; Hine, RJ; Koopman, WJ; Krumdieck, CL; Morgan, SL | 1 |
| Butterworth, CE; Cole, P; Hatch, KD; Sauberlich, HE; Soong, SJ; Tamura, T | 1 |
| Herbert, V; Herzlich, BC; Nawabi, I; Ranginwala, M | 1 |
| Mukai, F; Segal, A; Solomon, JJ | 1 |
| Cutler, RG; Hartman, PE; Kirsh, ME | 1 |
| Khan, AS; Roe, BA | 1 |
| James, SJ; Yin, L | 1 |
| Frenkel, K; Tofigh, S | 1 |
| Germain, GS; Hazelton, BJ; Houghton, JA; Houghton, PJ; Pennington, JW | 1 |
| Mironova, LL; Stobetskiĭ, VI | 1 |
| Das, KC; Herbert, V | 1 |
| August, EM; Brankovan, V; Ghazzouli, I; Lin, TS; Prusoff, WH; Shen, ZY; Yang, H | 1 |
| Bronk, JR; Hastewell, JG | 1 |
| Kusumoto, H; Kusumoto, T; Maehara, Y; Sakaguchi, Y; Sugimachi, K | 1 |
| Farquhar, D; Freed, JJ; Hampton, A | 1 |
| De Clercq, E; Griengl, H; Hayden, W; Penn, G; Rosenwirth, B | 1 |
| Branda, RF; Carney, JK; McCormack, JJ; Moore, AL; Perlmutter, CA | 1 |
| Galivan, J; Nimec, Z; Rhee, M | 1 |
| Ayisi, NK; Babiuk, LA; Gupta, SV | 1 |
| Bassendine, MF; Curtin, NJ; Harris, AL; James, OF | 1 |
| Machida, H | 1 |
| Cadet, J; Gaboriau, F; Moysan, A; Vigny, P; Voituriez, L | 1 |
| Dunkel, EC; Geary, PA; Imperia, PS; Lass, JH; Lazarus, HM; Pavan-Langston, D | 1 |
| Giese, RW; Trainor, TM; Vouros, P | 1 |
| Branda, RF; McCormack, JJ; Perlmutter, CA | 1 |
| Iseki, T; Iwasa, S; Kanazawa, S; Kondo, H; Okuda, K | 1 |
| Iwata, N; Karasawa, M; Katahira, H; Maekawa, T; Omine, M; Sugita, Y; Tsukamoto, N; Yamauchi, H; Yatabe, H | 1 |
| Bianchi, V; Pontis, E; Reichard, P | 1 |
| Diddens, H; Niethammer, D; Teufel, T | 1 |
| Bilimoria, MH; Gupta, SV | 1 |
| Bories, DM; Cartier, PH; Houllier, AM; Pérignon, JL; Thuillier, L | 1 |
| Anand, NN; Brown, DM; Salisbury, SA | 1 |
| Cortés, F; Morgan, WF; Wolff, S | 1 |
| Matthews, JH; Wickramasinghe, SN | 1 |
| Allison, DC; Anderson, S; Meyne, J; Ridolpho, PF; Robertson, J | 1 |
| Barrie, SE; Harrap, KR; Jeney, A; Lapis, K; Newell, DR; Otvös, L; Szabolcs, A; Taylor, GA | 1 |
| Lin, TS; Prusoff, WH | 1 |
| Iland, HJ; Laszlo, J; Sedwick, WD | 1 |
| Dobbin, J; Hamilton, E | 2 |
| Carmel, R; Karnaze, DS | 1 |
| Ayers, O; Malinowski, N; Moyer, JD | 1 |
| Amess, JA; Amos, RJ; Sourial, NA | 1 |
| Blais, J; Cadet, J; Ronfard-Haret, JC; Vigny, P; Voituriez, L | 1 |
| Carpenter, CB; Merrill, JP; Phillips, SM | 1 |
| Bean, B; Tomasz, A | 1 |
| Adams, BJ; Clancy, J; Elkins, WL | 1 |
| Mazurik, VK | 2 |
| Longland, JE; Wickramasinghe, SN | 1 |
| Hirsiger, H; Schaer, JC; Schindler, R; Siegers, MP | 1 |
| Foley, GE; Lazarus, H | 1 |
| Grossowicz, N; Mandelbaum-Shavit, F | 1 |
| Coyle, M; McMahon, M; Strauss, B | 1 |
| Ansfield, FJ; Ramirez, G | 1 |
| Chang, PK; Prusoff, WH; Voytek, P | 1 |
| Abbott, MT; McCroskey, RP; Shaffer, PM | 1 |
| Beck, CF; Ingraham, JL; Neuhard, J; Thomassen, E | 1 |
| Andersson, LC; Häyry, P | 1 |
| Magill, CW; Magill, JM; Spencer, RR | 1 |
| Ohyama, K | 1 |
| Bryan, AM; Olafsson, PG | 1 |
| Cheers, C; Miller, JF; Sprent, J | 1 |
| Maass, G; Seemayer, N | 1 |
| Gordy, W; Herak, JN | 1 |
| Ben-Porat, T; Kaplan, AS | 1 |
| Lea, MA; Morris, HP; Weber, G | 1 |
| Brandner, G; Haas, R; Maass, G; Werchau, H | 1 |
| Heidelberger, C; Umeda, M | 1 |
| Durham, JP; Ives, DH | 1 |
| Hoffman, J; Post, J | 1 |
| Tym, R | 1 |
| Hare, JD | 1 |
| Fritzsche, H; Tresselt, D; Zimmer, C | 1 |
| Brenner, L; Go, LT; Herbert, V; Tisman, G | 1 |
| Kit, S; Minekawa, Y | 1 |
| Newton, AA; Rubery, ED | 1 |
| Catovsky, D; Das, KC; Hoffbrand, V; Tripp, E | 1 |
| Weber, J | 1 |
| Chan, TS; Green, H; Meuth, M | 1 |
| Erbe, J; Plagemann, PG | 2 |
| Goodman, JI | 1 |
| Gauri, KK | 1 |
| Braek, OG; Smith-Kielland, I | 1 |
| Magdon, E | 1 |
| Firshein, W; Hasselbacher, P | 1 |
| Johnson, LI | 1 |
| Lüdemann, HD | 1 |
| Cadet, J; Teoule, R | 1 |
| Ganeshaguru, K; Hoffbrand, AV; Tattersall, MH | 1 |
| Goedde, HW; Singh, S; Willers, I | 1 |
| Gidali, J; Lajtha, LG; Lord, BI | 1 |
| Bock, E; Bock, O; Heit, W; Kubanek, B; Schreml, W | 1 |
| Mikhailov, VF | 1 |
| Bloch, A; McPartland, RP; Wang, MC; Weinfeld, H | 1 |
| Greenspan, EM; Schreiber, C; Waxman, S | 1 |
| Baccarani, M; Ernst, P; Killmann, SA | 1 |
| Cooper, M; Koutts, J; Van der Weyden, MB | 1 |
| Kehr, D; Maas, B; Müller, D; Wilmanns, W; Wilms, K | 1 |
| Berger, NA; Eichhorn, GL; Tarien, E | 1 |
| Harrap, KR; Tattersall, MH | 1 |
| Anderson, S; Bryan, AM; Davis, GC; Olafsson, PG | 1 |
| Pascoe, JM; Roberts, JJ | 1 |
| DaCosta, M; Kamen, B; Rothenberg, SP | 1 |
| Hall, JG; Moore, AR | 1 |
| Fuchs, JA; Neuhard, J | 1 |
| Karlström, O; Munch-Petersen, A; Uerkvitz, W | 1 |
| Nordin, AA | 1 |
| Gauri, KK; Walter, RD | 1 |
| Karasek, M; Lewis, RA | 1 |
| Barth, RF; Gillespie, GY; Gobuty, A | 2 |
| Hussa, RO; Pattillo, RA | 1 |
| Rocklin, RE | 1 |
| Edlis, H; Herbert, V; Tisman, G | 1 |
| Cooper, M; Firkin, BG; Van der Weyden, MB | 1 |
| Brenner, L; Herbert, V; Tisman, G | 1 |
| Hoffbrand, AV; Houlihan, CM; Scott, JM; Tripp, E | 1 |
| Chabner, BA; Young, RC | 1 |
| Concannon, JP; Hagemann, RF | 1 |
| Jasińska, JK; Steffen, JA; Swierkowska, KM | 1 |
| Cronkite, EP; Feinendegen, LE; Friedrich, G; Heiniger, HJ | 1 |
| Sakamoto, S; Takaku, F | 1 |
| Auletta, AE; Davis, J; Gery, AM; Mead, JA; Mishra, L; Parmar, A | 1 |
| Chwaliński, S; Ry'zewski, J | 1 |
| Doskocil, J; Paces, V | 1 |
| Schiek, W | 1 |
| Borsa, J; Whitmore, GF | 1 |
| Konobe, T; Mori, Y; Naito, M; Ono, K; Onoda, T | 1 |
| Burgan, MW; Cooper, AD; Herrmann, RL; White, CW | 1 |
| Fitch, CD; Hanna, C; Neufeld, OG | 1 |
| Mertes, MP; Shipchandler, MT | 1 |
| Danzig, M; Shapiro, R | 1 |
| Koskimies, S; Miller, JJ | 1 |
| Firkin, B; Rother, M; Van der Weyden, M | 1 |
| Leonard, NJ; Logue, MW | 1 |
| Green, R; Metz, J; Sive, J | 1 |
| Hall, JG; Parry, DM; Smith, ME | 1 |
| Rizki, RM; Rizki, TM | 1 |
| Kulakowska, I; Rabczenko, A; Shugar, D | 1 |
| Garcia, MN; Johnson, HA | 1 |
| Fisher, DB; Jensen, WA | 1 |
| Bertino, JR; Chabner, BA; Chello, PL | 1 |
| Shapiro, WR | 1 |
| Pisciotta, AV | 1 |
| Her, MO; Momparler, RL | 1 |
| Cantelmo, F; Feinendegen, LE; Friedrich, G; Heiniger, HJ | 1 |
| Rabczenko, A; Shugar, D | 1 |
| Kusaka, T | 1 |
| Hammond, D; Hyman, CB; Lampkin, BC; Pyesmany, A | 1 |
| Hall, TC; Roberts, D | 1 |
| Hall, TC; Roberts, D; Rosenthal, D | 1 |
| Bertino, JR; Hryniuk, WM | 2 |
| White, JE | 1 |
| Lampkin, BC; Mauer, AM; Nagao, T | 1 |
| Ernst, P; Killmann, SA | 1 |
| Weinstein, GD | 1 |
| Bertino, JR; Capizzi, R; Hryniuk, WM | 1 |
| Alpen, EL; Charruyer, F; Frindel, E; Kaplan, HS; Tubiana, M | 1 |
| Ayad, SR; Fox, BW; Fox, M | 1 |
| Gauri, KK; Malorny, G; Riehm, E | 1 |
| Loehr, EV; Roberts, D | 1 |
| Scocca, JJ | 1 |
| Guroff, G; Rhoads, CA | 1 |
| Bertino, JR; Fischer, GA; Hryniuk, WM | 1 |
| Dikowa, N; Matewa, V; Nachkov, D; Russeff, C; Wassilewa, L | 1 |
| Feinendegen, LE; Heiniger, HJ; Surianu, P | 1 |
| Kessel, D; Wodinsky, I | 1 |
| Fujiwara, Y; Heidelberger, C | 1 |
| Robins, RK; Witkowski, JT | 1 |
| Dubbs, DR; Kit, S; Nakajima, K | 1 |
| Fujiwara, Y; Heidelberger, C; Oki, T | 1 |
| Renis, HE | 1 |
| Das, KC; Hoffbrand, AV | 1 |
| Evans, VJ; Otani, TT; Price, FM; Rotherham, J | 1 |
| Greco, AE; Schneider, WC | 1 |
| Rao, PR | 1 |
| Brossmer, R; Röhm, E | 1 |
| Adelstein, SJ; Lyman, CP | 1 |
| Roy, JE; Tarr, HL; Yamamoto, M | 1 |
| Bosman, C; Feldman, JD | 1 |
| Baugnet-Mahieu, L; Goutier, R | 1 |
| Pietrzykowska, I; Shugar, D | 1 |
| Breitman, TR; Gallo, RC | 2 |
| Benes, L; Magdon, E; Winterfeld, G | 1 |
| Roberts, D; Wodinsky, I | 1 |
| Barth, PT; Beacham, IR; Eisenstark, A; Pritchard, RH | 1 |
| Jacobsen, DW; Kirchner, J; Schrecker, A | 1 |
| Heller, SR | 1 |
| Prescott, DM; Wykes, JR | 1 |
| Herbert, V; Metz, J; Waxman, S | 1 |
| Herbert, V; Waxman, S | 1 |
| Coleman, AW; Coleman, JR; Hartline, EJ | 1 |
| Himmelfarb, P; Martin, HE; Thayer, PS | 1 |
| Kang, S; Shapiro, R | 1 |
| Bond, VP; Feinendegen, LE; Hughes, WL | 1 |
| Jensen, WA; Yoo, B | 1 |
| Eidinoff, ML; Fox, JJ; Kim, JH | 1 |
| Bardos, TJ; Kalman, TI | 1 |
| Groth, DP; Jiang, N | 1 |
| Linn, BO; McPherson, JF; Shen, TY | 1 |
| Carter, CE; Nelson, DJ | 1 |
| Hashizume, T; Sasaki, Y | 1 |
| Commerford, SL; Drew, RM | 1 |
| Heidelberger, C; Isenberg, N | 1 |
| Breitman, TR; Gallo, RC; Perry, S | 1 |
| Holland, JF; Korn, R; Minnemeyer, HJ; O'Malley, J; Tieckelmann, H | 1 |
| Baum, CL; Rosenberg, IH; Selhub, J | 1 |
| Hofer, B; Köster, H | 1 |
| Cerna, I; Klubes, P; Meldon, MA | 1 |
| Beaulieu, D; Matiaszuk, NV; Pottier, A; Rosenblatt, DS; Vuchich, MJ; Whitehead, VM | 1 |
| Janz, C; Wigand, R | 1 |
| Rosenblatt, DS; Whitehead, VM | 1 |
| Burkhardt, U; Wigand, R | 1 |
| Feinendegen, LE; Mühlensiepen, H; Porschen, W | 1 |
| Gati, WP; Knaus, EE; Wiebe, LI | 1 |
| Besserer, JA; Boritzki, TJ; Elslager, EF; Fry, DW; Jackson, RC; Leopold, WR; Sloan, BJ | 1 |
| Hudson, JB | 1 |
| Chang, CT; De Clercq, E; Descamps, J; Mertes, MP; Schmidt, CL | 1 |
| Bergstrom, DE; Cheng, YC; Grill, S; Ruth, J | 1 |
| Gentry, GA; Veerisetty, V | 2 |
| de Clercq, E | 1 |
| Alenius, S; Gotthammar, B; Johansson, NG; Larsson, A; Oberg, B; Stening, G | 1 |
| Itoh, T; Kuwabara, M; Yoshii, G | 1 |
| Kano, Y; Kubota, T; Miura, Y; Sakamoto, S; Sakuraya, K; Taguchi, H; Takaku, F | 1 |
| Akinyanju, OO; Grange, A; Litwinczuk, RA; Wickramasinghe, SN | 1 |
| Fujii, S; Shirasaka, T | 1 |
| Beck, WS; Pelliniemi, TT | 1 |
| Abbott, MT; Hsu, CA; Jordan, RA | 1 |
| Calvert, AH; Harrap, KR; Jackman, AL; Taylor, GA | 1 |
| Bover, L; Cabral, S; Leis, S; Mordoh, J; Nembrot, M | 1 |
| Cooper, BA | 1 |
| Ayusawa, D; Balzarini, J; De Clercq, E; Seno, T | 1 |
| Balzarini, J; De Clercq, E | 1 |
| Balzarini, J; De Clercq, E; Hunston, RN; Jones, AS; McGuigan, C; Walker, RT | 1 |
| Langen, P; Liermann, B; Matthes, E | 1 |
| Das, KC; Garewal, G; Mohanty, D | 1 |
| Boehm, TL; Drahovsky, D; Kreis, W | 1 |
| Heartlein, MW; O'Neill, JP; Preston, RJ | 1 |
| Davidson, LA; Williams, WR | 1 |
| Kaplan, MS | 1 |
| Baden, JM; Kelley, M; Mazze, R; Rice, SA; Serra, M | 1 |
| Chacón, RD; Filmus, J; Mordoh, J | 1 |
| Browman, GP; Calvert, AH; Harrap, KR; Hart, LI; Taylor, GA | 1 |
| Evans, RM; Hakala, MT; Laskin, JD | 1 |
| Baptista, LC; Chanarin, I; Deacon, R; Reid, CD | 1 |
| Kumar, A; Nakatsugawa, S; Sugahara, T | 1 |
| Cox, EC; Erlich, HA | 1 |
| Sauer, H; Schalhorn, A | 1 |
| Hida, K; Kano, Y; Sakamoto, S; Suda, K; Takaku, F | 1 |
| Spector, R; Suleiman, SA | 1 |
| Berlinger, WG; Spector, R | 1 |
| Carmel, R; Goodman, SI | 1 |
| Antoni, F; Péterfy, F; Puskás, M | 1 |
| Spector, R | 1 |
| Iwata, N; Maekawa, T; Omine, M; Yamauchi, H | 1 |
| Ishii, T; Ishizawa, S; Kataoka, K; Matsuki, S; Okabe, T | 1 |
| Clarke, R; Murphy, RF; Van den Berg, HW | 1 |
| Bricaud, H; Desgranges, C; Rabaud, M; Razaka, G | 1 |
| Deveski, WB; Dudman, NP; Tattersall, MH | 1 |
| Chanarin, I; Deacon, R; Lumb, M; Perry, J | 1 |
| Laszlo, J; Sedwick, WD | 1 |
| Bedros, AA; Carmel, R; Goodman, SI; Mace, JW | 1 |
| Chanarin, I; Deacon, R; Halsey, M; Lumb, M; Minty, B; Nunn, J; Perry, J | 1 |
| Blehová, Z; Dienstbier, Z; Masopust, J; Sámal, M | 1 |
| McKenna, B; Scott, JM; Weir, DG | 1 |
| Das, KC; Herbert, V; Manusselis, C | 1 |
| Fernandes-Costa, F; Metz, J; Miller, H | 1 |
| Bøyum, A; Løvhaug, D; Nordlie, EM; Seeberg, E | 1 |
| Haga, N; Kuriyama, Y; Ogura, H; Takayanagi, H; Tokumaru, K | 1 |
| Gimsing, P; Hippe, E | 1 |
| Porter, DJ; Short, SA | 1 |
| Maeda, M; Saneyoshi, M; Tokuzen, R; Yamaguchi, T; Yoshida, M | 1 |
| Docherty, JJ; Wilber, BA | 1 |
| Kulikowski, T | 1 |
| Liguori, A; Napoli, A; Sindona, G | 2 |
| Bonizzi, L; Focher, F; Garbesi, A; Maga, G; Niccolai, D; Poli, G; Ponti, W; Spadari, S; Verri, A | 1 |
| Hengstschläger, M; Wawra, E | 1 |
| Meistrich, ML; Pollack, A; Terry, NH; Van, NT | 1 |
| Ektova, LV; Iartseva, IV; Iavorskaia, NP; Ivanova, TP; Khorosheva, EV; Mel'nik, SIa | 1 |
| Decker-Samuelian, K; Singh, US; Solomon, JJ | 1 |
| Bianchini, F; Cadet, J; Delatour, T; Douki, T | 1 |
| Johansson, M; Karlsson, A | 1 |
| Focher, F; Priori, G; Spadari, S; Tondelli, L; Verri, A | 1 |
| Dams, R; Goethals, P; Lemahieu, I; Van der Eycken, J; van Eijkeren, M; Volders, F | 1 |
| Ansorge, W; Cremer, T; Fischer, R; Saffrich, R; Stelzer, EH; Trendelenburg, MF; Zink, D | 1 |
| Fukada, S; Iwamoto-Tanaka, N; Kasai, H | 1 |
| Bergqvist, S; Bijapur, J; Brown, T; Fox, KR; Keppler, MD | 1 |
| Eckstein, F; Kore, AR | 1 |
| Aherne, GW; Benstead, J; Clarke, SJ; Farrugia, DC; Jackman, AL; Pritchard, DM | 1 |
| Eriksson, S; Wang, L | 1 |
| Evans, VJ; Price, FM; Rotherham, J | 2 |
| Garcia, GA; Kung, FL; Nonekowski, ST | 1 |
| Kumar, R | 1 |
| Brouwer, J; de Ruijter, M; Lugtenburg, J; Ouwerkerk, N; Raap, J; Steenweg, M; van Boom, JH | 1 |
| De Bondt, P; Dierckx, RA; Peeters, M; Van de Wiele, C; Vermeersch, H | 1 |
| Hirano, M; Martí, R; Nishigaki, Y | 2 |
| Andrzejewska, M; Górska, A; Kamiński, J; Kazimierezuk, Z | 1 |
| Oberdorfer, F; Yu, CS | 1 |
| EIDINOFF, ML; RICH, MA | 1 |
| NICHOL, CA; WHITE, PJ | 1 |
| LOVE, R; STUDZINSKI, GP | 1 |
| HARDING, CV; HUGHES, WL; WHEELER, MB; WILSON, WL | 1 |
| KILLMANN, SA | 1 |
| BARCLAY, M; JACQUEZ, JA; KRENITSKY, TA | 1 |
| BOND, SB; KRISS, JP | 1 |
| BOUZAS, A | 1 |
| HOLTZER, H; NAMEROFF, M; OKAZAKI, K; STOCKDALE, F | 1 |
| FORCE, EE; HAFF, RF; STEWART, RC | 1 |
| KOEHNLEIN, W; MUELLER, A | 1 |
| STONE, JE | 1 |
| RUSCH, HP; SACHSENMAIER, W | 1 |
| GREEN, H; TODARO, GJ | 1 |
| ARBER, W; BROWN, A | 1 |
| CHAUBE, S; MURPHY, ML | 1 |
| FOX, BW; PRUSOFF, WH | 1 |
| COOPER, EH; MILTON, JD | 1 |
| DUBBS, DR; KIT, S | 1 |
| KIT, S; MUNYON, W | 1 |
| Bölske, G; Carnrot, C; Eriksson, S; Wang, L; Wehelie, R | 1 |
| Hirano, M; Martí, R; Nishigaki, Y; Nishino, I; Spinazzola, A; Tadesse, S | 1 |
| Baker, G; Decile, KC; Hyde, DM; Larson, SD; Mansoor, JK; Pinkerton, K; Plopper, CG; Schelegle, ES; Tarkington, BK | 1 |
| Eriksson, S; Wang, L; Wehelie, R | 1 |
| Bianchi, V; Crocco, L; Fabris, S; Ferraro, P; Pontarin, G; Reichard, P | 1 |
| Hirano, M; Lagier-Tourenne, C; Martí, R; Nishigaki, Y; Valentino, ML | 1 |
| Goodrich-Blair, H; Orchard, SS | 1 |
| Burman, JF; Mollin, DL | 1 |
| Gador, A; Hakala, K; Huttunen, S; Kiljunen, S; Lönnberg, H; Pinta, E; Pluta, P; Skurnik, M | 1 |
| Alonso, M; Marky, LA; Rentzeperis, D; Shikiya, R; Soto, AM | 1 |
| Douglas, KT; Edwards, PN; Freeman, S; Gbaj, A; Jaffar, M; Reigan, P | 1 |
| Clarke, SJ; Hoskins, J; Li, KM; Rivory, LP; Sharma, R | 1 |
| Andreu, AL; Anikster, Y; Hirano, M; Illa, I; Lara, MC; Madoz, P; Martí, R; Massuet, L; Valentino, ML; Weiss, B | 1 |
| Fujimoto, K; Ogino, M; Okamura, D; Yoshimura, Y | 1 |
| Christensen, E; Christensen, M; Elmaci, M; Ozel, A; Schwartz, M; Vissing, J; Yavuz, H | 1 |
| Black, DH; Eberle, R; Focher, F; Gambino, JJ; Lossani, A; Maioli, A; Medveczky, M; Medveczky, P; Shugar, D; Spadari, S; Verri, A; Wright, GE | 1 |
| Carelli, V; Hahn, A; Hirano, M; López, LC; Lyzak, J; Manes, JL; Martí, R; Tadesse, S; Valentino, ML | 1 |
| Clarke, SJ; Li, KM; Rivory, LP | 1 |
| Barnard, DL; Humphreys, DE; Hurst, BL; Smee, DF | 1 |
| Bain, MD; Bax, BE; Moran, NF; Muqit, MM | 1 |
| Hirose, W; Matsuda, A; Sato, K | 2 |
| Du, Q; Huang, Z; Lin, L; Momin, RK; Sheng, J | 1 |
| Fawcett, H; Lehmann, A; Limsirichaikul, S; Niimi, A; Ogi, T; Yamashita, S | 1 |
| Fornace, AJ; Gonzalez, FJ; Idle, JR; Krausz, KW; Patterson, AD; Slavík, J; Tyburski, JB | 1 |
| Arora, A; Grunebaum, E; Min, W; Roifman, CM; Yu, Y | 1 |
| Champavier, Y; Guilloton, M; Lucas, R; Teste, K; Zerrouki, R | 1 |
| Hu, P; Liang, QL; Luo, GA; Wang, YM; Xia, JF; Zou, TT | 1 |
| Granger, A; Kim, GJ; Kushner, JA; Long, SH; Rankin, MM; Sartori, DJ; Schiffman, AB; Stein, GM; Teta, M; Tuttle, AH; Virgilio, C; Zhou, D | 1 |
| Bahde, R; Guerrero, C; Gupta, S; Wang, J; Wang, Y; Yuan, B | 1 |
| Chi, W; Cong, S; Liang, P; Qu, D; Ren, X; Wang, G; Wang, Z; Zhang, B; Zhou, L | 1 |
| Cavanagh, BL; Meedeniya, AC; Norazit, A; Walker, T | 1 |
| Al-Momani, E; Dinger, C; Glatting, G; Morgenroth, A; Mottaghy, FM; Reske, SN; Zlatopolskiy, BD | 1 |
| Burns, AR; Field, LJ; Frounfelter, TD; Grivas, JA; Lafontant, PJ; Lala, TD; Lesch, MA; Reuter, SP | 1 |
| Hirano, M; López, LC; Martí, R | 1 |
| Fowler, DH; Lavie, A; Medin, JA; Neschadim, A; Sato, T; Wang, JC | 1 |
| McCann, KA; McKee, EE; Williams, DW | 1 |
| Li, J; Lin, G; Sun, Y; Wang, L; Xie, J; Zhang, K; Zhang, R | 1 |
| Blain, JC; Kuang, Y; Peng, X; Sun, H | 1 |
| Caporali, L; Carelli, V; Contin, M; De Giorgio, R; Mohamed, S | 1 |
| Anda, S; Boye, E; Grallert, B | 1 |
| Alizadeh, E; García, G; Madugundu, GS; Sanche, L; Sanz, AG; Wagner, JR | 1 |
| Li, J; Wang, H; Wang, J; Wang, X; Wang, Y; Xie, L; Xiong, S; Zhang, G; Zhang, R | 1 |
| Schmidl, SR; Stülke, J; Wang, L | 1 |
| Friggeri, A; Lepape, A; Malcus, C; Monneret, G; Pachot, A; Poitevin-Later, F; Poujol, F; Rimmelé, T; Textoris, J; Venet, F | 1 |
| Adam, T; Friedecký, D; Koberna, K; Ligasová, A; Strunin, D | 1 |
| Chomicz, L; Jian, Y; Li, L; Lin, G | 1 |
| Field, MS; Finkelstein, JL; Martiniova, L; Perry, CA; Stover, PJ | 1 |
| Boschetti, E; Caporali, L; Capristo, M; Carelli, V; Contin, M; D'Angelo, R; De Giorgio, R; Dotti, MT; Mohamed, S; Pinna, AD; Pironi, L; Rinaldi, R | 1 |
| Bender, B; Billing, H; Blom, HJ; Haack, TB; Marquetand, J; Röeben, B; Sanchez-Albisua, I; Schöls, L; Synofzik, M | 1 |
| Cabrera-Pérez, R; Cámara, Y; Hirano, M; Martí, R; Torres-Torronteras, J; Vila-Julià, F; Viscomi, C; Zeviani, M | 1 |
| Dudarev, AN; Gorodetskaya, AY; Miroshnichenko, SM; Tkachenko, TA; Tkachenko, VI; Usynin, IF | 1 |
| Greenberg, MM; Zheng, L | 1 |
| Baus, D; Berdis, AJ; Hernandez-Sanchez, W; Taylor, DJ; Whited, TL; Xu, M; Zeng, X; Zhang, J | 1 |
| Bax, BE; Enguita, FJ; Levene, M | 1 |
| Baraniak, D; Barciszewski, J; Boryski, J; Michalska, L; Szymańska-Michalak, A; Wawrzyniak, D | 1 |
| Chinnery, PF; Coulter, LL; Parkes, M; Patel, R; Rimmer, J; Swift, O | 1 |
| Fritz, Y; Müller, S; Wagenknecht, HA | 1 |
| Gao, X; Huang, Z; Li, J; Morris, PF; Yang, C; Zhang, X; Zhu, C | 1 |
| Chen, F; Chen, Y; Hapeshi, A; Lee, YJ; Michniewski, S; Millard, AD; Puxty, RJ; Rihtman, B; Scanlan, DJ; Waterfield, NR; Weigele, P; Zhan, Y | 1 |
| Belousov, VV; Enikolopov, GN; Maltsev, DI; Mellanson, KA; Podgorny, OV | 1 |
| Baccolini, C; Herde, M; Niehaus, M; Specht, A; Straube, H; Witte, CP | 1 |
| Cao, X; Kawara, H; Kose, C; Lindsey-Boltz, LA; Sancar, A; Selby, CP; Wang, L; Yang, Y | 1 |
8 review(s) available for thymidine and deoxyuridine
| Article | Year |
|---|---|
The positive control of cell proliferation by the interplay on calcium ions and cyclic nucleotides. A review.
Topics: Acetylcholine; Animals; Bucladesine; Calcium; Cell Division; Cell Line; Concanavalin A; Cyclic AMP; Cyclic GMP; Deoxyuridine; DNA; Floxuridine; Growth Hormone; Humans; Liver; Lymphocyte Activation; Models, Biological; Parathyroid Hormone; Pindolol; Prostaglandins; Rats; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymidine; Thymidine Monophosphate | 1976 |
Chemical and biological consequences of beta-decay. Part 1.
Topics: Bromodeoxyuridine; Carbon Radioisotopes; Cytosine; Deoxyuridine; Free Radicals; Idoxuridine; Iodine Radioisotopes; Isotope Labeling; Phenols; Phosphorus Radioisotopes; Radioactive Tracers; Radioactivity; Radioisotopes; Succinates; Sulfur Radioisotopes; Thymidine; Tritium; Tyrosine; Uracil | 1977 |
Biochemical modulation of fluorouracil by dipyridamole: preclinical and clinical experience.
Topics: Colonic Neoplasms; Deoxyuridine; Dipyridamole; DNA Damage; DNA, Neoplasm; Drug Interactions; Fluorouracil; Humans; Infusions, Intravenous; Leucovorin; Methotrexate; Nucleosides; Nucleotides; RNA, Neoplasm; Thymidine; Tumor Cells, Cultured; Uridine Monophosphate | 1992 |
[On the action mechanism of antiviral agents].
Topics: Amantadine; Antiviral Agents; Chemical Phenomena; Chemistry; Cytarabine; Deoxyuridine; DNA, Viral; Guanidines; Idoxuridine; Imidazoles; Indoles; Thymidine; Virus Replication | 1969 |
Nucleoside analogues as antiviral agents.
Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Arabinonucleosides; Bromodeoxyuridine; Chemical Phenomena; Chemistry; Cytarabine; Deoxyuridine; Guanine; Herpesviridae Infections; Humans; Idoxuridine; Nucleosides; Ribavirin; Thymidine; Virus Diseases; Viruses | 1981 |
Structure-activity relationships and conformational features of antiherpetic pyrimidine and purine nucleoside analogues. A review.
Topics: Animals; Antiviral Agents; Deoxyguanosine; Deoxyuridine; Herpesviridae; Humans; Molecular Conformation; Structure-Activity Relationship; Thymidine | 1994 |
Radiolabelled thymidines and deoxyuridines for measuring cellular proliferation in tumours--an update.
Topics: Cell Division; Clinical Trials as Topic; Deoxyuridine; Humans; Neoplasms; Pyrimidines; Radionuclide Imaging; Radiopharmaceuticals; Thymidine | 2002 |
Thymidine analogues for tracking DNA synthesis.
Topics: Animals; Bromodeoxyuridine; Cell Proliferation; Cells, Cultured; Click Chemistry; Deoxyuridine; DNA; Fluorescent Dyes; Humans; Staining and Labeling; Stem Cell Niche; Thymidine | 2011 |
2 trial(s) available for thymidine and deoxyuridine
| Article | Year |
|---|---|
Evaluation of the deoxyuridine suppression test by using whole blood samples from folic acid-supplemented subjects.
Topics: Adult; Deoxyuridine; DNA; Erythrocytes; Female; Folic Acid; Humans; Male; Middle Aged; Nutritional Status; Random Allocation; Thymidine; Uterine Cervical Dysplasia; Vitamin B 12 | 1990 |
Pemetrexed pharmacokinetics and pharmacodynamics in a phase I/II study of doublet chemotherapy with vinorelbine: implications for further optimisation of pemetrexed schedules.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carcinoma, Non-Small-Cell Lung; Deoxyuridine; Dietary Supplements; Dose-Response Relationship, Drug; Female; Folic Acid; Glutamates; Guanine; Homocysteine; Humans; Lung Neoplasms; Male; Methylmalonic Acid; Middle Aged; Pemetrexed; Thymidine; Thymidylate Synthase; Vinblastine; Vinorelbine; Vitamin B 12 | 2007 |
465 other study(ies) available for thymidine and deoxyuridine
| Article | Year |
|---|---|
Synthesis and biological activities of some uronic acids, uronates, uronamides, and urononitriles of pyrimidine nucleosides.
Topics: Animals; Cell Division; Cells, Cultured; Chick Embryo; Pyrimidine Nucleosides; Sarcoma 180; Simplexvirus; Streptococcus; Structure-Activity Relationship; Substrate Specificity; Thymidine Kinase; Thymidylate Synthase; Uronic Acids; Virus Replication | 1978 |
L-thymidine is phosphorylated by herpes simplex virus type 1 thymidine kinase and inhibits viral growth.
Topics: Cell Division; Cell Survival; Deoxyribonucleosides; HeLa Cells; Humans; Leucine; Simplexvirus; Stereoisomerism; Thymidine; Thymidine Kinase; Uridine | 1992 |
Synthesis and tumor uptake of 5-82Br- and 5-131I-labeled 5-halo-1-(2-fluoro-2-deoxy-beta-D-ribofuranosyl)uracils.
Topics: Animals; Biological Transport; Bromine Radioisotopes; Chemical Phenomena; Chemistry; DNA; Female; Floxuridine; Iodine Radioisotopes; Isotope Labeling; Lung Neoplasms; Mice; Molecular Structure; Structure-Activity Relationship; Tissue Distribution | 1989 |
Synthesis and tumor uptake of 5-halo-1-(2'-fluoro-2'-deoxy-beta-D-ribofuranosyl)[2-14C]uracils.
Topics: Animals; Antimetabolites, Antineoplastic; Biological Transport; Carcinoma; Carrier Proteins; Erythrocytes; Female; Floxuridine; Liver; Lung Neoplasms; Membrane Proteins; Metabolic Clearance Rate; Mice; Mice, Inbred Strains; Nucleoside Transport Proteins; Structure-Activity Relationship; Tissue Distribution | 1987 |
Thymidine phosphorylase. Substrate specificity for 5-substituted 2'-deoxyuridines.
Topics: Animals; Deoxyuridine; Horses; In Vitro Techniques; Models, Biological; Pentosyltransferases; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Substrate Specificity; Thymidine Phosphorylase | 1980 |
Virtual combinatorial syntheses and computational screening of new potential anti-herpes compounds.
Topics: Anilides; Animals; Antiviral Agents; Chlorocebus aethiops; Esters; Herpesvirus 1, Human; Inhibitory Concentration 50; Models, Molecular; Phenols; Structure-Activity Relationship; Vero Cells; Viral Plaque Assay | 1999 |
Synthesis of 5-(carboranylalkylmercapto)-2'-deoxyuridines and 3-(carboranylalkyl)thymidines and their evaluation as substrates for human thymidine kinases 1 and 2.
Topics: Boron Compounds; Deoxyuridine; Humans; Phosphorylation; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity; Thymidine; Thymidine Kinase; Tumor Cells, Cultured | 1999 |
A new synthetic analogue of thymidine, 7-(3-bromo-phenoxy)-thymidine, inhibits the proliferation of tumor cells.
Topics: Cell Division; HeLa Cells; Humans; Thymidine | 2005 |
Kinetic parameters and recognition of thymidine analogues with varying functional groups by thymidine phosphorylase.
Topics: Kinetics; Molecular Structure; Structure-Activity Relationship; Substrate Specificity; Thymidine; Thymidine Phosphorylase | 2008 |
Antiviral activity of 2,3'-anhydro and related pyrimidine nucleosides against hepatitis B virus.
Topics: Antiviral Agents; Hepatitis B virus; Pyrimidine Nucleosides | 2010 |
Biochemical classification of herpes simplex virus types 1 and 2, and of intermediate strains on the basis of different susceptibilities of thymidine kinase to thymidine analogues.
Topics: Bromodeoxyuridine; Cell-Free System; Culture Techniques; Deoxyuridine; Mercaptoethanol; Simplexvirus; Thymidine; Thymidine Kinase; Thymine Nucleotides | 1976 |
Varying effects of deoxynucleosides on the incorporation of thymidine into the DNA of monolayer and suspension cultures.
Topics: Animals; Ascites; Bone Marrow; Bone Marrow Cells; Cell Survival; Cells, Cultured; Deoxycytidine; Deoxyuridine; DNA; HeLa Cells; Hydrogen-Ion Concentration; Leukemia L1210; Lymphocytes; Neoplasms, Experimental; Thymidine | 1977 |
Deoxypyrimidine nucleoside metabolism in varicella-zoster virus-infected cells.
Topics: Cell Line; Cytidine; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; Enzyme Induction; Herpesvirus 3, Human; Humans; Hydrogen-Ion Concentration; Molecular Weight; Thymidine; Thymidine Kinase | 1978 |
Biological effects of 5-carboxy-2'-deoxyuridine: hydrolysis product of 5-trifluoromethyl-2'-deoxyuridine.
Topics: Antiviral Agents; Deoxyuridine; DNA; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; RNA; Temperature; Thymidine; Time Factors; Trifluridine | 1978 |
Intraocular penetration of trifluridine.
Topics: Aqueous Humor; Cell Membrane Permeability; Cornea; Deoxyuridine; Herpes Zoster Ophthalmicus; Humans; Iritis; Thymidine; Trifluridine | 1979 |
Metabolism of pyrimidine deoxyribonucleosides in Neurospora crassa.
Topics: Autoradiography; Carbon Radioisotopes; Cell-Free System; Chromatography, Paper; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; Mixed Function Oxygenases; Models, Chemical; Mutation; Neurospora; Neurospora crassa; Pyrimidines; Thymidine; Thymine; Uracil | 1975 |
Effects of thymidine analogs upon growth control in cultured hormone-dependent ray ovary cells.
Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Culture Media; Cytarabine; Deoxyuridine; DNA; Female; Floxuridine; Hormones; Hydroxyurea; Idoxuridine; Kinetics; Ovarian Neoplasms; Rats; Thymidine | 1975 |
Methotrexate inhibition of CCRF-CEM cultures of human lymphoblasts.
Topics: Cell Division; Cell Line; Deoxycytidine; Deoxyuridine; DNA, Neoplasm; Floxuridine; Folic Acid Antagonists; Humans; Hypoxanthines; Leucovorin; Leukemia, Lymphoid; Methotrexate; Purines; Thymidine | 1975 |
Toxoplasma gondii: characterization of a mutant resistant to 5-fluorodeoxyuridine.
Topics: Animals; Cell Line; Deoxyuridine; DNA; Drug Resistance; Floxuridine; Fluorouracil; Genes; Mutation; RNA; Thymidine; Toxoplasma; Uridine | 1977 |
Deoxyuridine suppression test: a comparison of two methods and effect of thymidine on the incorporation of 3H-deoxyuridine into DNA in human bone marrow cells.
Topics: Anemia, Megaloblastic; Bone Marrow; Bone Marrow Cells; Deoxyuridine; Depression, Chemical; DNA; Dose-Response Relationship, Drug; Humans; Methods; Thymidine | 1977 |
Detection of induced resistance in short-term-tests. Adriamycin-resistant sarcoma 180.
Topics: Animals; Cell Line; Deoxyuridine; Doxorubicin; Drug Resistance; Mice; Sarcoma 180; Thymidine; Time Factors; Triaziquone; Uridine | 1978 |
Thymidylate synthetase and dihydrofolic acid reductase in the stimulated human lymphocyte.
Topics: Cells, Cultured; Deoxyuridine; Floxuridine; Humans; Lectins; Lymphocytes; Methotrexate; Methyltransferases; Tetrahydrofolate Dehydrogenase; Thymidine; Thymidylate Synthase | 1978 |
Distinguishing between membrane transport and intracellular metabolism of fluorodeoxyuridine in Ehrlich ascites tumor cells by application of kinetic and high performance liquid chromatographic techniques.
Topics: Animals; Biological Transport, Active; Carcinoma, Ehrlich Tumor; Cell Membrane; Chromatography, High Pressure Liquid; Deoxyuridine; Floxuridine; Fluorouracil; Kinetics; Mice; Thymidine; Uridine | 1979 |
The effect of 5-bromodeoxyuridine on interferon production in human cells.
Topics: Bromodeoxyuridine; Cell Division; Cell Line; Deoxycytidine; Deoxyuridine; DNA; Floxuridine; Humans; Idoxuridine; Interferons; Thymidine | 1979 |
Effects of thymidine analogues on murine and human cells.
Topics: Animals; Bromodeoxyuridine; Cell Count; Cell Line; Deoxyuridine; Fibroblasts; Floxuridine; Humans; Idoxuridine; Mice; Neoplasms; Neoplasms, Experimental; Thymidine | 1979 |
Role of cyclic nucleotides and calcium in the positive control of cell proliferation.
Topics: Animals; Calcium; Cell Division; Cell Membrane; Cyclic AMP; Cyclic GMP; Deoxyuridine; DNA; Hepatectomy; Liver; Models, Biological; Parathyroid Glands; Rats; T-Lymphocytes; Thymidine; Time Factors | 1975 |
The mechanism of 5-fluorouridine toxicity in Novikoff hepatoma cells.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Division; Cell Line; Deoxyribonucleosides; Deoxyuridine; DNA, Neoplasm; Guanosine; In Vitro Techniques; Liver Neoplasms; RNA, Neoplasm; RNA, Ribosomal; Thymidine; Time Factors; Uridine | 1976 |
Utilization of 3H from deoxyuridine and thymidine for synthesis of DNA and tother macromolecules in various organs of the rat.
Topics: Animals; Bone Marrow; Carcinoma, Hepatocellular; Deoxyuridine; DNA; Fluorouracil; Intestinal Mucosa; Liver; Liver Neoplasms; Rats; Rats, Inbred ACI; RNA; Thymidine; Tritium | 1977 |
Uridine phosphorylase activity of isolated plasma membranes of rat liver.
Topics: Acid Phosphatase; Animals; Cell Membrane; Deoxyuridine; Glucose-6-Phosphatase; Glutamate Dehydrogenase; Glycerol; Liver; Male; Nucleotidases; Pentosyltransferases; Polyethylene Glycols; Rats; Subcellular Fractions; Thymidine; Thymidine Phosphorylase; Uridine; Uridine Phosphorylase | 1977 |
Antiviral activity of 5-methylthiomethyl-2'-deoxyuridine and other 5-substituted 2'-deoxyuridines.
Topics: Antiviral Agents; Cytopathogenic Effect, Viral; Deoxyuridine; Simplexvirus; Thymidine; Virus Replication | 1979 |
[Anaemia induced by vitamin B12 or folate deficiency: diagnostic value of the "dU suppression" test (author's transl)].
Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Anemia, Sideroblastic; Bone Marrow; Deoxyuridine; Diagnosis, Differential; DNA; Folic Acid Deficiency; Leukemia, Myeloid, Acute; Male; Thymidine; Vitamin B 12 Deficiency | 1978 |
The in vitro effect of trimethoprim on blastogenic transformation of human peripheral blood lymphocytes.
Topics: Autoradiography; Cells, Cultured; Concanavalin A; Deoxyuridine; Folic Acid; Formates; Humans; In Vitro Techniques; Leucine; Leucovorin; Lymphocyte Activation; Lymphocytes; Thymidine; Time Factors; Trimethoprim; Uridine | 1977 |
The effect of deoxyuridine, vitamin B12, folate and alcohol on the uptake of thymidine and on the deoxynucleoside triphosphate concentrations in normal and megaloblastic cells.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow; Cells, Cultured; Deoxyadenine Nucleotides; Deoxyuridine; DNA; Ethanol; Folic Acid; Humans; Leucovorin; Lymphocytes; Tetrahydrofolates; Thymidine; Thymine Nucleotides; Vitamin B 12 | 1978 |
The biochemistry of the citrovorum factor rescue effect in normal bone marrow cells after high-dose methotrexate.
Topics: Adult; Bone Marrow; Cells, Cultured; Deoxyuridine; Humans; Leucovorin; Lymphocytes; Male; Methotrexate; Middle Aged; Osteosarcoma; Thymidine; Thymidine Kinase | 1979 |
Automated quantitative analysis of single and double label autoradiographs.
Topics: Animals; Autoradiography; Cell Nucleus; Computers; Cytological Techniques; Deoxyuridine; Jejunum; Mice; Photometry; Thymidine | 1979 |
Design of species- or isozyme-specific enzyme inhibitors. 1. Effect of thymidine substituents on affinity for the thymidine site of hamster cytoplasmic thymidine kinase.
Topics: Animals; Cricetinae; Cytoplasm; Deoxycytidine; Deoxyuridine; Humans; In Vitro Techniques; Isoenzymes; Kidney; Kinetics; Methods; Mitochondria; Structure-Activity Relationship; Substrate Specificity; Thymidine; Thymidine Kinase; Thymine Nucleotides | 1979 |
Deoxyuridine metabolism in human megaloblastic marrow cells.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow; Deoxyuridine; DNA; Folic Acid; Folic Acid Deficiency; Humans; Methotrexate; Thymidine; Thymidylate Synthase; Vitamin B 12; Vitamin B 12 Deficiency | 1979 |
Serologic assay of DNA base damage. I. 5-Hydroxymethyldeoxyuridine, a radiation product of thymidine.
Topics: Animals; Cobalt Radioisotopes; Coliphages; Cross Reactions; Deoxyuridine; DNA; Haptens; Immunoassay; Rabbits; Serum Albumin, Bovine; Thymidine; Viral Plaque Assay | 1978 |
Effects of thymidine analogs on Syrian hamster melanoma cells: phenotypes arising from selection for analog resistance.
Topics: Aminopterin; Cell Line; Deoxyuridine; DNA; Drug Resistance; Phenotype; Selection, Genetic; Thymidine | 1977 |
Effect of folate and cobalamin compounds on the deoxyuridine suppression test in vitamin B12 and folate deficiency.
Topics: Deoxyuridine; Folic Acid; Folic Acid Deficiency; Humans; Methotrexate; Thymidine; Vitamin B 12; Vitamin B 12 Deficiency | 1978 |
Decay-induced incorporation of tritium into nucleosides in aqueous solutions.
Topics: Deoxyuridine; Isotope Labeling; Nucleosides; Thymidine; Tritium | 1978 |
[Short-term incubation in vitro with precursors of nucleic acids on human primary tumors and metastases of carcinoma of the breast (author's transl)].
Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Deoxyuridine; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Female; Humans; Lymphatic Metastasis; Methotrexate; Thymidine; Uridine | 1978 |
5-Nitro-2'-deoxyuridine and 5-nitro-2'-deoxyuridine 5'-monophosphate: antiviral activity and inhibition of thymidylate synthetase in vivo.
Topics: Antiviral Agents; Cells, Cultured; Deoxyuracil Nucleotides; Deoxyuridine; DNA; Drug Interactions; Methyltransferases; Thymidine; Thymidylate Synthase | 1978 |
The use of [125I]deoxyuridine for semi-microevaluation of human lymphocyte response to phytohemagglutinin in vitro.
Topics: Adult; Deoxyuridine; Female; Humans; Lectins; Lymphocyte Activation; Male; Thymidine | 1978 |
The effect of homocysteine, methionine, serine and glycine on DNA synthesis by human normoblastic and megaloblastic bone marrow cells.
Topics: Bone Marrow Cells; Cell Survival; Deoxyuridine; DNA; Erythrocytes, Abnormal; Glycine; Homocysteine; Humans; Megaloblasts; Methionine; Serine; Thymidine | 1978 |
Pretherapeutic cytostatic agent sensitivity testing of breast cancer.
Topics: Breast Neoplasms; Cyclophosphamide; Deoxyuridine; Doxorubicin; Drug Resistance; Female; Humans; RNA, Neoplasm; Thymidine; Tritium; Uridine | 1978 |
N-Glycosidase activity in extracts of Bacillus subtilis and its inhibition after infection with bacteriophage PBS2.
Topics: Bacillus subtilis; Bacteriophages; Cell-Free System; Chromatography, Thin Layer; Coliphages; Deoxyuridine; DNA Viruses; DNA, Viral; Edetic Acid; Enzyme Repression; Escherichia coli; Glycoside Hydrolases; Hot Temperature; Kinetics; Nucleic Acid Denaturation; Sulfhydryl Reagents; Thymidine; Tritium; Uracil; Uridine | 1975 |
Relative biochemical aspects of low and high doses of methotrexate in mice.
Topics: Animals; Bone Marrow; Deoxyuridine; DNA; Dose-Response Relationship, Drug; Infusions, Parenteral; Intestine, Small; Male; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Thymidine; Thymidine Monophosphate | 1977 |
Cobalamin dependent methionine synthesis and methyl-folate-trap in human vitamin B12 deficiency.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Bone Marrow; Bone Marrow Cells; Deoxyuridine; Folic Acid; Humans; Methotrexate; Methyltransferases; Tetrahydrofolates; Thymidine; Vitamin B 12 Deficiency | 1977 |
The effect of anticonvulsant drugs on thymidine and deoxyribosenucleic acid synthesis by human marrow cells.
Topics: Anticonvulsants; Bone Marrow; Bone Marrow Cells; Deoxyuridine; DNA; Folic Acid; Humans; Phenytoin; Thymidine; Vitamin B 12 | 1977 |
Comparative effects on growth and tumorigenicity of mouse melanoma cells by thymidine and its analogs, 5-ethyl- and 5-bromodeoxyuridine.
Topics: Animals; Bromodeoxyuridine; Cell Division; Cells, Cultured; Deoxyuridine; DNA, Neoplasm; Kinetics; Melanins; Melanoma; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Thymidine; Transplantation, Homologous | 1977 |
[Correlation between the effects of cytostatic agents on leukemia L 1210 in vivo and in the short term test in vitro (author's transl)].
Topics: Animals; Cell Count; Culture Techniques; Deoxyuridine; Doxorubicin; Female; Leucine; Leukemia L1210; Methotrexate; Mice; Thymidine; Time Factors; Uridine; Vinblastine | 1977 |
Successful therapy of herpes hominis keratitis in rabbits by 5-iodo-5'-amino-2'5'-dideoxyuridine (AIU): a novel analog of thymidine.
Topics: Administration, Topical; Animals; Deoxyuridine; Disease Models, Animal; Drug Administration Schedule; Drug Evaluation, Preclinical; Keratitis, Dendritic; Male; Rabbits; Thymidine | 1976 |
Stacking self-association of pyrimidine nucleosides and of cytosines: effects of methylation and thiolation.
Topics: Binding Sites; Calorimetry; Cytosine; Deoxyuridine; Kinetics; Pyrimidine Nucleosides; Temperature; Thermodynamics; Thymidine; Uridine | 1976 |
Inhibition of nucleic acid synthesis by the di-n-butyl ester of methotrexate.
Topics: Cell Line; Deoxyuridine; DNA, Neoplasm; Drug Resistance; Methotrexate; Thymidine; Time Factors | 1976 |
Comparative effects of selected antifolates on transforming human lymphocytes and on established human lymphoblastic cell lines.
Topics: Animals; Cattle; Cell Line; Deoxyuridine; Folic Acid Antagonists; Humans; In Vitro Techniques; Lectins; Liver; Lymphocyte Activation; Methotrexate; Mitosis; Stimulation, Chemical; Thymidine; Time Factors | 1976 |
Arabinosyl nucleosides inhibit Toxoplasma gondii and allow the selection of resistant mutants.
Topics: Animals; Cells, Cultured; Cytarabine; Deoxyuridine; DNA; Drug Resistance; Mutation; RNA; Thymidine; Toxoplasma; Vidarabine | 1976 |
Deoxypyrimidineuria in the course of chemotherapy in M. Hodgkin.
Topics: Cyclophosphamide; Deoxycytidine; Deoxyuridine; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Male; Prednisone; Procarbazine; Sex Factors; Splenectomy; Thymidine; Vinblastine; Vincristine | 1976 |
Altered morphology and pathways of DNA synthesis in small intestinal epithelium in dietary folate deficiency [proceedings].
Topics: Animals; Deoxyuridine; DNA; Epithelium; Folic Acid Deficiency; Intestinal Mucosa; Intestine, Small; Rats; Thymidine | 1976 |
The mechanism of action of methotrexate in cultured L5178Y leukemia cells.
Topics: Animals; Cell Line; Cell Survival; Deoxyuridine; DNA, Neoplasm; Hypoxanthines; Kinetics; Leukemia, Lymphoid; Methotrexate; Mice; Models, Biological; Thymidine; Time Factors | 1975 |
Biochemical properties of 5-sulfur-substituted pyrimidine nucleosides and nucleotides.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cytosine Nucleotides; Deoxyuridine; DNA; DNA, Neoplasm; Kinetics; Mice; Polyribonucleotide Nucleotidyltransferase; Pyrimidine Nucleotides; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Thymidine; Uracil Nucleotides | 1975 |
Chloramphenicol-a possible role in the treatment of leukaemia?
Topics: Anemia, Hemolytic; Anemia, Hypochromic; Anemia, Megaloblastic; Bone Marrow; Chloramphenicol; Deoxyuridine; Depression, Chemical; DNA; DNA, Neoplasm; Female; Humans; In Vitro Techniques; Leukemia, Myeloid; Middle Aged; Thymidine | 1976 |
Effect of cytostatic drugs on nucleic acid synthesis in mouse thymocytes and chick embryo cells.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Chick Embryo; Cytarabine; Dactinomycin; Deoxyadenosines; Deoxyuridine; DNA; Fluorouracil; Melphalan; Methotrexate; Mice; Mice, Inbred Strains; Thymidine; Thymus Gland; Triaziquone; Tritium; Uridine; Vinblastine | 1975 |
Fate of H2-activated T lymphocytes in syngeneic hosts. I. Fate in lymphoid tissues and intestines traced with 3H-thymidine, 125I-deoxyuridine and 51chromium.
Topics: Animals; Chromium Radioisotopes; Deoxyuridine; Histocompatibility Antigens; Intestine, Large; Intestine, Small; Iodine Radioisotopes; Lymphoid Tissue; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; T-Lymphocytes; Thymidine; Transplantation, Isogeneic | 1976 |
Sequential use of methotrexate, folinic acid, and cytosine arabinoside in the treatment of acute leukemia.
Topics: Adult; Bone Marrow; Bone Marrow Cells; Child; Cytarabine; Deoxyuridine; DNA; Drug Administration Schedule; Female; Humans; In Vitro Techniques; Leucovorin; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Middle Aged; Mitosis; Thymidine; Thymine | 1976 |
Reaction of ribonucleosides and deoxynucleosides with copper(II) acetate.
Topics: Acetates; Chemical Phenomena; Chemistry; Copper; Cytidine; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; Ribonucleosides; Spectrum Analysis; Thymidine; Uridine | 1975 |
Effects of methotrexate esters on normal and psoriatic skin.
Topics: Chemical Phenomena; Chemistry; Chronic Disease; Deoxyuridine; Depression, Chemical; DNA; Humans; Lipids; Methotrexate; Psoriasis; Skin; Solubility; Thymidine | 1975 |
Urine excretion of nucleosides in Hodgkin's disease treated by combined chemotherapy.
Topics: Cyclophosphamide; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; Drug Therapy, Combination; Hodgkin Disease; Humans; Prednisolone; Thymidine; Time Factors; Vinblastine | 1975 |
Preferential incorporation of 3H-deoxycytidine into chicken bursal cells. Comparison of radiolabelled nucleosides as lymphoid cell markers in chickens and mice.
Topics: Animals; Bursa of Fabricius; Chickens; Deoxycytidine; Deoxyuridine; DNA; Female; Intestinal Mucosa; Lymph Nodes; Mice; Spleen; Thymidine; Thymus Gland | 1975 |
On the mode of action of 5-vinyl-2'-deoxyuridine.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Division; Deoxyuridine; DNA, Neoplasm; Phosphates; Phosphorus Radioisotopes; Thymidine; Vinyl Compounds | 1975 |
The anti-folate effect of methionine on bone marrow of normal and vitamin B12 deficient rats.
Topics: Animals; Bone Marrow; Deoxyuridine; DNA; Folic Acid; Folic Acid Antagonists; Homocysteine; Liver; Male; Methionine; Methionine Adenosyltransferase; Rats; Thymidine; Vitamin B 12; Vitamin B 12 Deficiency | 1975 |
Lack of specific correlation of the deoxycytidine triphosphate pool level with rate of DNA synthesis.
Topics: Cell Line; Cytidine; Cytosine Nucleotides; Deoxycytidine; Deoxyribonucleotides; Deoxyuridine; DNA Replication; Thymidine | 1975 |
Comparative effects of ftorafur and 5-fluorouracil on DNA synthesis in rat small intestine.
Topics: Animals; Deoxyuridine; DNA; Fluorouracil; Furans; Intestine, Small; Male; Rats; Thymidine; Thymidylate Synthase | 1975 |
Kinetic alterations induced by 5-fluorouracil in bone marrow, intestinal mucosa, and tumor.
Topics: Animals; Bone Marrow; Carcinoma, Ehrlich Tumor; Cell Division; Deoxyuridine; DNA; DNA, Neoplasm; Dose-Response Relationship, Drug; Fluorouracil; Intestinal Mucosa; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Thymidine | 1976 |
The effect of sulfasalazine on bovine endothelial cell proliferation and cell cycle phase distribution. Comparison with olsalazine, 5-aminosalicylic acid, and sulfapyridine.
Topics: Aminosalicylic Acids; Animals; Cattle; Cell Count; Cell Cycle; Deoxyuridine; Endothelium, Vascular; Mesalamine; Sulfapyridine; Sulfasalazine; Tetrahydrofolates; Thymidine; Time Factors; Tritium | 1992 |
Mechanism of mutagenicity by 5-hydroperoxymethyl-2'-deoxyuridine, an intermediate product of ionizing radiation, in bacteria. HPMdU bacterial mutagenicity and oxidation of DNA bases.
Topics: Deoxyuridine; DNA Damage; DNA, Bacterial; Free Radicals; Iron; Iron Chelating Agents; Mutagenesis; Mutagenicity Tests; Mutagens; Oxidants; Oxidation-Reduction; Salmonella typhimurium; Thymidine; Thymine | 1992 |
Inhibition of poly(ADP-ribose)polymerase activity by nucleoside analogs of thymidine.
Topics: Animals; Benzamides; Deoxyuridine; Dideoxynucleosides; Kinetics; Mice; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Thymidine; Tumor Cells, Cultured | 1992 |
Synthesis and biological activity of 2'-deoxy-4'-thio pyrimidine nucleosides.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Carcinoma, Squamous Cell; Chemical Phenomena; Chemistry; Cytomegalovirus; Deoxycytidine; Deoxyuridine; Humans; Leukemia L1210; Leukemia, T-Cell; Mice; Simplexvirus; Thionucleosides; Thiouridine; Thymidine; Tumor Cells, Cultured | 1991 |
[Telomeric chromosome fusion in cells with micronuclei under the combined action of hyperthermia and hypothermia and halogenated analogs of thymidine].
Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; Deoxyuridine; Idoxuridine; Micronuclei, Chromosome-Defective; Telomere; Temperature; Thymidine | 1991 |
High-performance liquid chromatographic analysis of 5-ethylpyrimidines and 5-methylpyrimidines in plasma.
Topics: Animals; Antiviral Agents; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Deoxyuridine; Humans; Liver; Rats; Thymidine; Thymine; Uracil | 1991 |
Folate-deficient human lymphoblasts: changes in deoxynucleotide metabolism and thymidylate cycle activities.
Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyuridine; Dose-Response Relationship, Drug; Folic Acid; Folic Acid Deficiency; Humans; Lymphocyte Activation; Lymphocytes; Nucleotides; Thymidine; Thymidylate Synthase; Thymine Nucleotides | 1991 |
Use of the deoxyuridine suppression test to evaluate localized folate deficiency in rat colonic epithelium.
Topics: Animals; Cells, Cultured; Colon; Deoxyuridine; DNA; Epithelium; Fluorouracil; Folic Acid; Male; Rats; Rats, Inbred Strains; Thymidine | 1991 |
Methotrexate therapy in rheumatoid arthritis patients diminishes lectin-induced mononuclear cell proliferation.
Topics: Arthritis, Rheumatoid; Cell Division; Cells, Cultured; Culture Media; Deoxyuridine; DNA; Female; Folic Acid; Humans; Lectins; Leukocytes, Mononuclear; Male; Methotrexate; Middle Aged; Phytohemagglutinins; Thymidine; Tritium | 1990 |
Synergy of inhibition of DNA synthesis in human bone marrow by azidothymidine plus deficiency of folate and/or vitamin B12?
Topics: Bone Marrow; Deoxyuridine; DNA; Folic Acid Deficiency; Humans; Pyrimidines; Tetrahydrofolates; Thymidine; Vitamin B 12 Deficiency; Zidovudine | 1990 |
In vitro reactions of glycidol with pyrimidine bases in calf thymus DNA.
Topics: 1-Propanol; Animals; Cattle; Chromatography, High Pressure Liquid; Deoxycytidine; Deoxyuridine; DNA; Epoxy Compounds; Ethers, Cyclic; Hydrogen-Ion Concentration; Propanols; Pyrimidines; Thymidine; Thymus Gland | 1990 |
Absence of deoxyuridine and 5-hydroxymethyldeoxyuridine in the DNA from three tissues of mice of various ages.
Topics: Aging; Animals; Brain; Chromatography, High Pressure Liquid; Deoxyuridine; DNA; Embryo, Mammalian; Intestinal Mucosa; Liver; Male; Mice; Mice, Inbred C57BL; RNA; Thymidine | 1986 |
Aminoacylation of synthetic DNAs corresponding to Escherichia coli phenylalanine and lysine tRNAs.
Topics: Base Sequence; Deoxyuridine; Dimethyl Sulfoxide; DNA; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Lysine-tRNA Ligase; Molecular Sequence Data; Phenylalanine-tRNA Ligase; RNA, Bacterial; RNA, Transfer, Amino Acyl; Spermidine; Structure-Activity Relationship; Thymidine | 1988 |
Diet-induced DNA damage and altered nucleotide metabolism in lymphocytes from methyl-donor-deficient rats.
Topics: Animals; Choline; Choline Deficiency; Deoxyuridine; Diet; DNA Damage; DNA Replication; Folic Acid; Folic Acid Deficiency; Liver; Lymphocytes; Male; Methionine; NAD; Nucleotides; Rats; Rats, Inbred F344; Reference Values; RNA; Spleen; Thymidine | 1989 |
Effect of metals on nucleoside hydroperoxide, a product of ionizing radiation in DNA.
Topics: Chromatography, High Pressure Liquid; Copper; Deferoxamine; Deoxyuridine; DNA; Edetic Acid; Formates; Iron; Pentetic Acid; Thymidine | 1989 |
Mutants of human colon adenocarcinoma, selected for thymidylate synthase deficiency.
Topics: Adenocarcinoma; Animals; Cell Division; Cell Line; Cell Survival; Clone Cells; Colonic Neoplasms; Deoxyuridine; DNA Replication; Humans; Kinetics; Mice; Mutation; Neoplasm Transplantation; Nucleoside-Phosphate Kinase; Thymidine; Thymidylate Synthase; Transplantation, Heterologous; Tumor Cells, Cultured | 1989 |
[Telomeric fusion of the chromosomes in cells with micronuclei during the subsequent incorporation into the DNA of thymidine halogenated analogs].
Topics: Animals; Cells, Cultured; Chromosomes; Cricetinae; Cricetulus; Demecolcine; Deoxyuridine; DNA; Idoxuridine; Micronuclei, Chromosome-Defective; Thymidine | 1989 |
In vitro DNA synthesis by megaloblastic bone marrow: effect of folates and cobalamins on thymidine incorporation and de novo thymidylate synthesis.
Topics: Adolescent; Adult; Aged; Bone Marrow; Deoxyuridine; DNA; Erythrocytes, Abnormal; Female; Folic Acid; Humans; Male; Megaloblasts; Middle Aged; Thymidine; Thymidine Kinase; Thymidine Monophosphate; Vitamin B 12 | 1989 |
Synthesis and antiviral activity of several 2,5'-anhydro analogues of 3'-azido-3'-deoxythymidine, 3'-azido-2',3'-dideoxyuridine, 3'-azido-2',3'-dideoxy-5-halouridines, and 3'-deoxythymidine against human immunodeficiency virus and Rauscher-murine leukemia
Topics: Antiviral Agents; Chemical Phenomena; Chemistry; Deoxyuridine; HIV-1; Rauscher Virus; Thymidine | 1989 |
The specificity of pyrimidine nucleoside transport and metabolism by rat jejunum in vitro.
Topics: Animals; Biological Transport, Active; Deoxyuridine; Intestinal Mucosa; Jejunum; Male; Pyrimidine Nucleosides; Rats; Rats, Inbred Strains; Thymidine; Thymine; Uracil; Uridine | 1989 |
Species differences in substrate specificity of pyrimidine nucleoside phosphorylase.
Topics: Animals; Colon; Deoxyuridine; Digestive System; Digestive System Neoplasms; Fluorouracil; Humans; Liver; Mice; Pentosyltransferases; Pyrimidine Phosphorylases; Rats; Rectum; Species Specificity; Stomach; Substrate Specificity; Thymidine; Uridine | 1989 |
Evidence for acyloxymethyl esters of pyrimidine 5'-deoxyribonucleotides as extracellular sources of active 5'-deoxyribonucleotides in cultured cells.
Topics: Animals; Blood Physiological Phenomena; Cells, Cultured; Deoxyuracil Nucleotides; Deoxyuridine; DNA; Esters; Fluorodeoxyuridylate; Fluorouracil; Mice; Thymidine; Thymidine Monophosphate | 1989 |
Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cell Line; Chemical Phenomena; Chemistry; Deoxyuridine; Foscarnet; Herpes Simplex; Mice; Organophosphorus Compounds; Pharmaceutical Preparations; Phosphonoacetic Acid; Prodrugs; Rabbits; Simplexvirus; Thymidine; Vero Cells | 1988 |
Inhibition of lymphocyte nucleic acid metabolism and antibody production by trimetrexate.
Topics: Antibody Formation; Deoxyuridine; DNA; Humans; Interphase; Lymphocytes; Methotrexate; Nucleic Acids; Quinazolines; Thymidine; Trimetrexate | 1987 |
Synergistic growth inhibition of rat hepatoma cells exposed in vitro to N10-propargyl-5,8-dideazafolate with methotrexate or the lipophilic antifolates trimetrexate or metoprine.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Cycle; Deoxyuridine; Folic Acid; Folic Acid Antagonists; Liver Neoplasms, Experimental; Methotrexate; Pyrimethamine; Quinazolines; Rats; Thymidine; Thymidylate Synthase; Trimetrexate | 1987 |
Combination chemotherapy: interaction of 5-methoxymethyldeoxyuridine with trifluorothymidine, phosphonoformate and acycloguanosine against herpes simplex viruses.
Topics: Acyclovir; Animals; Antiviral Agents; Deoxyuridine; DNA, Viral; Drug Combinations; Drug Resistance, Microbial; Drug Synergism; Encephalitis; Foscarnet; Herpes Simplex; Male; Mice; Organophosphorus Compounds; Phosphonoacetic Acid; Rabbits; Simplexvirus; Thymidine; Trifluridine; Vidarabine; Virus Replication | 1985 |
Inhibition of the growth of human hepatocellular carcinoma in vitro and in athymic mice by a quinazoline inhibitor of thymidylate synthase, CB3717.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Deoxyuridine; Dose-Response Relationship, Drug; Folic Acid; Humans; In Vitro Techniques; Liver Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Quinazolines; Thymidine | 1986 |
Susceptibility of varicella-zoster virus to thymidine analogues.
Topics: Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Cytarabine; Deoxyuridine; Fibroblasts; Herpesvirus 3, Human; Humans; Neutralization Tests; Simplexvirus; Thymidine | 1986 |
Chemical structure of 3-carbethoxypsoralen-DNA photoadducts.
Topics: Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Deoxycytidine; Deoxyuridine; DNA; Furocoumarins; Light; Photochemistry; Spectrometry, Fluorescence; Stereoisomerism; Thymidine | 1986 |
An in vitro study of ophthalmic antiviral agent toxicity on rabbit corneal epithelium.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cell Survival; Cornea; Deoxyuridine; Epithelium; Idoxuridine; In Vitro Techniques; Rabbits; Thymidine; Trifluridine | 1988 |
Mass spectrometry of electrophore-labeled nucleosides. Pentafluorobenzyl and cinnamoyl derivatives.
Topics: Benzyl Compounds; Chromatography, Gas; Cinnamates; Deoxyribonucleosides; Deoxyuridine; Electrochemistry; Fluorine; Gas Chromatography-Mass Spectrometry; Mass Spectrometry; Thymidine | 1988 |
Cellular pharmacology of chloroquinoxaline sulfonamide and a related compound in murine B16 melanoma cells.
Topics: Animals; Cell Division; Cell Line; Chromatography, High Pressure Liquid; Deoxyuridine; DNA; Flow Cytometry; Leucovorin; Melanoma; Mice; Quinoxalines; Sulfanilamides; Sulfaquinoxaline; Tetrahydrofolate Dehydrogenase; Thymidine | 1988 |
Effect of methotrexate on the deoxyuridine suppression test: results with different cell preparations.
Topics: Bone Marrow; Bone Marrow Cells; Cells, Cultured; Deoxyuridine; Depression, Chemical; DNA; Formyltetrahydrofolates; Humans; Methotrexate; Microchemistry; Tetrahydrofolates; Thymidine | 1988 |
[Deoxyuridine suppression test. A modified method and specificity in megaloblastic anemia].
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Deoxyuridine; Diagnosis, Differential; Humans; Myelodysplastic Syndromes; Thymidine | 1987 |
Regulation of pyrimidine deoxyribonucleotide metabolism by substrate cycles in dCMP deaminase-deficient V79 hamster cells.
Topics: Animals; Cell Division; Cell Line; Cricetinae; Cytidine Diphosphate; DCMP Deaminase; Deoxycytidine; Deoxycytidine Monophosphate; Deoxycytosine Nucleotides; Deoxyribonucleotides; Deoxyuridine; DNA; Nucleotide Deaminases; Pyrimidines; Thymidine; Thymidine Monophosphate; Thymine Nucleotides; Uridine Diphosphate | 1987 |
High-dose methotrexate therapy with leucovorin rescue: in vitro investigations on human osteosarcoma cell lines.
Topics: Cell Line; Cell Survival; Deoxyuridine; DNA, Neoplasm; Humans; Leucovorin; Methotrexate; Osteosarcoma; Thymidine; Tumor Cells, Cultured | 1987 |
Comparison of the mutagenic activity of 5-hydroxymethyldeoxyuridine with 5-substituted 2'-deoxyuridine analogs in the Ames Salmonella/microsome test.
Topics: Animals; Deoxyuridine; Male; Microsomes, Liver; Rats; Rats, Inbred Strains; Salmonella typhimurium; Structure-Activity Relationship; Thymidine | 1986 |
Metabolism of pyrimidine bases and nucleosides by pyrimidine-nucleoside phosphorylases in cultured human lymphoid cells.
Topics: Cells, Cultured; Deoxyuridine; Humans; Lymphocytes; Nucleosides; Pentosyltransferases; Pyrimidine Phosphorylases; Pyrimidines; Thymidine; Uridine | 1987 |
The stability of oligodeoxyribonucleotide duplexes containing degenerate bases.
Topics: Base Sequence; Cytosine; Deoxyuridine; Drug Stability; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Thermodynamics; Thymidine | 1987 |
Effect of exogenous thymidine on sister-chromatid exchange frequency in Chinese hamster ovary cells with bromodeoxyuridine- and chlorodeoxyuridine-substituted chromosomes.
Topics: Animals; Bromodeoxyuridine; Cell Cycle; Cell Line; Cricetinae; Cricetulus; Deoxyuridine; Sister Chromatid Exchange; Thymidine | 1987 |
Acquired folate deficiency in phytohaemagglutinin-stimulated human lymphocytes.
Topics: Cells, Cultured; Culture Media; Deoxyuridine; Dose-Response Relationship, Drug; Folic Acid; Folic Acid Deficiency; Humans; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Thymidine | 1986 |
Alterations in the DNA metabolism of MCa-11 mouse mammary tumor cells grown in vivo and in vitro.
Topics: Animals; Cells, Cultured; Deoxyuridine; DNA, Neoplasm; Female; Interphase; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Thymidine; Tritium | 1986 |
5-Ethyl-2'-deoxyuridine: an explanation for its lack of cytotoxic action in vivo.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cells, Cultured; Deoxyuridine; Kinetics; Mitosis; Nucleic Acid Synthesis Inhibitors; Pentosyltransferases; Pyrimidine Phosphorylases; Thymidine; Thymidine Kinase; Thymidylate Synthase | 1986 |
Enhancement of the anticancer activity of bis(2-chloroethyl)nitrosourea in mice by coadministration of 2'-deoxyuridine, 2'-deoxycytidine, or thymidine.
Topics: Animals; Carmustine; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; Drug Synergism; Leukemia L1210; Melanoma, Experimental; Mice; Ribonucleosides; Thymidine | 1987 |
Paradoxical effect of BW 301U, a lipophilic antifolate, on methotrexate-inhibitable deoxyuridine incorporation by human hematopoietic cells.
Topics: Antineoplastic Agents; Biological Transport; Bone Marrow; Deoxyuridine; Folic Acid Antagonists; Hematopoietic Stem Cells; Humans; In Vitro Techniques; Leukemia, Myeloid, Acute; Methotrexate; Pyrimidines; Thymidine; Tritium | 1985 |
The validity of the labelling index in tumour studies.
Topics: Animals; Deoxyuridine; DNA; Isotope Labeling; Male; Mice; Mice, Inbred C3H; Mice, Inbred CBA; Mitosis; Mitotic Index; Neoplasms, Experimental; Thymidine; Tritium | 1985 |
The deoxyuridine suppression test identifies subtle cobalamin deficiency in patients without typical megaloblastic anemia.
Topics: Aged; Bone Marrow; Bone Marrow Examination; Deoxyuridine; DNA; Female; Humans; In Vitro Techniques; Male; Middle Aged; Thymidine; Vitamin B 12; Vitamin B 12 Deficiency | 1985 |
Salvage of circulating pyrimidine nucleosides by tissues of the mouse.
Topics: Animals; Cytidine; Deoxycytidine; Deoxyuridine; Half-Life; Male; Metabolic Clearance Rate; Mice; Pyrimidine Nucleosides; Thymidine; Tissue Distribution; Uracil; Uridine | 1985 |
Role of S-adenosylmethionine in DNA synthesis and haemopoiesis.
Topics: Bone Marrow; Deoxyuridine; DNA Replication; Hematopoiesis; Humans; Methionine; Nitrous Oxide; S-Adenosylmethionine; Thymidine; Vitamin B 12 | 1985 |
Triplet excited states of 4',5'-photomonoadducts of 3-carbethoxypsoralen and 8-methoxypsoralen with DNA nucleosides.
Topics: Deoxyuridine; Furocoumarins; Lasers; Methoxsalen; Thymidine; Ultraviolet Rays | 1985 |
Immunosuppressive alpha globulin from bovine thymus. II. Mode of action.
Topics: Alpha-Globulins; Animals; Carbon Isotopes; Cattle; Cell Membrane; Cell Migration Inhibition; Deoxyuridine; DNA; Guinea Pigs; Humans; Immunosuppression Therapy; Iodine Isotopes; Lectins; Leucine; Lymphocyte Activation; Macrophages; Microscopy, Phase-Contrast; Phospholipids; RNA; Thymidine; Thymus Gland; Tritium; Tuberculin Test | 1971 |
Selective utilization of pyrimidine deoxyribonucleosides for deoxyribonucleic acid synthesis in pneumococcus.
Topics: Autoradiography; Carbon Isotopes; Chromatography, Ion Exchange; Cytidine; Deoxyribonucleosides; Deoxyuridine; DNA, Bacterial; Mutation; RNA, Bacterial; Streptococcus pneumoniae; Thymidine | 1973 |
Fate of deoxyribonucleic acid-synthesizing cells and their progeny in a local graft-versus-host reaction.
Topics: Animals; Autoradiography; Bone Marrow; Cell Movement; Cell Nucleolus; Deoxyuridine; DNA; Graft vs Host Reaction; Immune Sera; Iodine Isotopes; Kidney; Lymph Nodes; Rats; Rats, Inbred Lew; Spleen; Thymidine; Thymus Gland; Time Factors | 1973 |
[A method of simultaneous quantitative determination of thymidine and deoxyuridine in rat urine].
Topics: Animals; Chromatography, Paper; Deoxyuridine; DNA; Rats; Thymidine | 1966 |
Rate of incorporation of tritiated thymidine into DNA of normoblastic and megaloblastic bone marrow cells in vitro.
Topics: Alcoholism; Anemia, Hypochromic; Anemia, Macrocytic; Bone Marrow; Bone Marrow Cells; Deoxyuridine; DNA; Erythropoiesis; Folic Acid Deficiency; Humans; Liver Diseases; Thymidine; Tritium; Vitamin B 12 Deficiency | 1974 |
Determination of rates of DNA synthesis in cultured mammalian cell populations.
Topics: Animals; Autoradiography; Cell Division; Cell Line; Cells, Cultured; Deoxyuridine; DNA; DNA, Neoplasm; Kinetics; Mast-Cell Sarcoma; Methotrexate; Mice; Mitosis; Neoplasm Transplantation; Thymidine | 1974 |
The response in vitro, of continuous cultures of human lymphoblasts (CCRF-CEM cells) to chemotherapeutic agents.
Topics: Animals; Azaserine; Chloramphenicol; Culture Media; Culture Techniques; Cyclophosphamide; Cytarabine; Dactinomycin; Deoxyuridine; Floxuridine; Fluorouracil; Humans; Hydrocortisone; Lymphocytes; Mechlorethamine; Mercaptopurine; Methotrexate; Mitomycins; Puromycin; Thymidine; Triazines; Vincristine | 1967 |
Effect of folinate on thymidine uptake by Pediococcus cerevisiae.
Topics: Aminopterin; Carbon Isotopes; Deoxyuridine; Floxuridine; Glucose; Hydrogen-Ion Concentration; Iodoacetates; Leucovorin; Methotrexate; Pediococcus; Temperature; Thymidine; Thymine; Tritium; Uracil | 1968 |
Failure of alkylated HEp.2 cells to replicate newly synthesized DNA.
Topics: Alkanes; Alkylating Agents; Carbon Isotopes; Carcinoma; Cell Line; Centrifugation, Density Gradient; Chemical Precipitation; Culture Media; Culture Techniques; Deoxyuridine; DNA; DNA Repair; DNA Replication; Floxuridine; Humans; Hydroxyurea; Laryngeal Neoplasms; Methods; Sulfonic Acids; Thymidine; Tritium | 1971 |
Phase I and II studies of 2'-deoxy-5-(trifluoromethyl)-uridine (NSC-75520).
Topics: Blood Cell Count; Bone Marrow; Breast Neoplasms; Colonic Neoplasms; Deoxyuridine; Female; Floxuridine; Half-Life; Humans; Leukopenia; Rectal Neoplasms; Thrombocytopenia; Thymidine; Time Factors | 1971 |
Kinetic and photochemical studies of 3-N-methyl-5-iodo-2-'-deoxyuridine. Sensitization of ultraviolet inactivation of thymidine kinase by 3-N-methyl-5-iodo-2'-deoxyuridine and other halogenated analogs of thymidine.
Topics: Adenosine Triphosphate; Bromodeoxyuridine; Carbon Isotopes; Cytosine Nucleotides; Deoxyribonucleotides; Deoxyuridine; Escherichia coli; Floxuridine; Idoxuridine; Iodine; Kinetics; Magnesium; Methylation; Photochemistry; Photolysis; Radiation Effects; Spectrophotometry; Stimulation, Chemical; Thymidine; Thymidine Kinase; Thymine Nucleotides; Ultraviolet Rays | 1972 |
Substrate specificity of the hydroxylase reaction in which thymidine is converted to thymine ribonucleoside.
Topics: Air; Calcium Phosphates; Carbon Isotopes; Cytidine; Deoxyadenosines; Deoxyribonucleosides; Deoxyuridine; Guanosine; Hydroxylation; Mixed Function Oxygenases; Neurospora; Neurospora crassa; Nitrogen; Nucleosides; Oxygen; Ribonucleosides; Structure-Activity Relationship; Thymidine; Thymine; Time Factors; Tritium; Uridine | 1972 |
Metabolism of pyrimidines and pyrimidine nucleosides by Salmonella typhimurium.
Topics: Aminohydrolases; Cytidine; Cytosine; Deoxyuridine; Floxuridine; Flucytosine; Fluorouracil; Genetics, Microbial; Genotype; Mutation; Nucleosides; Nucleotidyltransferases; Pentosyltransferases; Phosphotransferases; Pyrimidines; Salmonella typhimurium; Thymidine; Uracil; Uracil Nucleotides; Uridine | 1972 |
Allograft immunity in vitro. V. Generation of cytotoxic effector cells in mixed lymphocyte culture and the specificity of target cell lysis.
Topics: Animals; Autoradiography; Cell Count; Cell Separation; Colchicine; Cytotoxicity Tests, Immunologic; Deoxyuridine; Female; Lectins; Lymphocyte Culture Test, Mixed; Macrophages; Male; Mast-Cell Sarcoma; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Thymidine; Tritium | 1973 |
Relationship between (8-14C)adenosine transport and growth inhibition in Neurospora crassa strain ad-8.
Topics: Adenosine; Carbon Radioisotopes; Deoxyribonucleosides; Deoxyuridine; Electron Transport; Guanosine; Inosine; Micropore Filters; Neurospora; Neurospora crassa; Nucleosides; Spores, Fungal; Thymidine; Uridine | 1974 |
Properties of 5-bromodeoxyuridine-resistant lines of higher plant cells in liquid culture.
Topics: Aminopterin; Biological Transport; Bromodeoxyuridine; Carbon Radioisotopes; Cell Division; Cell Line; Centrifugation, Density Gradient; Culture Media; Deoxyuridine; DNA; Drug Resistance; Floxuridine; Glycine; Glycine max; Hypoxanthines; Nitrosoguanidines; Plants; Protoplasts; Thymidine; Thymidine Kinase; Time Factors; Tritium | 1974 |
The influence of 5-halo substituents on the thermal depyrimidination of the glycosidic bond in 2'-deoxyuridines.
Topics: Bromodeoxyuridine; Calorimetry; Deoxyuridine; Floxuridine; Guanosine; Iodine; Molecular Conformation; Temperature; Thermodynamics; Thymidine; Thymine; Uracil | 1974 |
Interaction of thymus lymphocytes with histoincompatible cells. IV. Mixed lymphocyte reactions of activated thymus lymphocytes.
Topics: Animals; Autoradiography; Deoxyuridine; DNA; Histocompatibility; Iodine Radioisotopes; Lectins; Lymph; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred CBA; Radiation Chimera; Radiation Effects; Spleen; T-Lymphocytes; Thoracic Duct; Thymidine; Tritium | 1974 |
[Studies on the multiplication of SV40 in tissue cultures].
Topics: Antigens; Autoradiography; Culture Techniques; Deoxyuridine; Fluorescent Antibody Technique; Kidney; Simian virus 40; Thymidine; Tritium; Virus Cultivation | 1965 |
ESR study of nucleosides and nucleotides bombarded with hydrogen atoms.
Topics: Chemical Phenomena; Chemistry, Physical; Cytosine Nucleotides; Deoxyuridine; DNA; Electron Spin Resonance Spectroscopy; Guanine Nucleotides; Hydrogen; Nucleosides; Nucleotides; Thymidine; Uracil Nucleotides; Uridine | 1966 |
Correlation between replication and degradation of cellular DNA in polyoma virus-infected cells.
Topics: Carbon Isotopes; Centrifugation, Density Gradient; Chromatography; Culture Techniques; Deoxyuridine; DNA; DNA, Viral; Fluorescent Antibody Technique; Polyomavirus; Thymidine; Tritium | 1967 |
DNA metabolism in liver and kidney tumors of different growth rates.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Deoxyuridine; DNA, Neoplasm; Kidney Neoplasms; Liver Neoplasms; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Thymidine | 1968 |
Incorporation of iododeoxyuridine into cellular deoxyribonucleic acid synthesized after infection with simian virus 40.
Topics: Animals; Carbon Isotopes; Centrifugation, Density Gradient; Cesium; Chlorides; Culture Techniques; Deoxyuridine; DNA; Haplorhini; Iodine; Kidney; Nucleosides; Simian virus 40; Thymidine; Tritium; Virus Diseases | 1968 |
Comparative studies of fluorinated pyrimidines with various cell lines.
Topics: Animals; Carcinoma, Hepatocellular; Culture Techniques; Deoxyuridine; Depression, Chemical; DNA, Neoplasm; Floxuridine; HeLa Cells; Leukemia, Experimental; Liver Neoplasms; Neoplasms, Experimental; Nucleosides; Phosphotransferases; Pyrimidines; RNA, Neoplasm; Thymidine; Thymidine Kinase; Uridine | 1968 |
Deoxycytidine kinase. I. Distribution in normal and neoplastic tissues and interrelationships of deoxycytidine and 1-beta-D-arabinofuranosylcytosine phosphorylation.
Topics: Adenocarcinoma; Animals; Carcinoma, Hepatocellular; Cattle; Chick Embryo; Chromatography, Ion Exchange; Cytarabine; Cytosine Nucleotides; Deoxyuridine; Escherichia coli; Fibrosarcoma; Kinetics; Leukemia L1210; Leukemia, Experimental; Liver Neoplasms; Lymphoid Tissue; Mice; Mitosis; Neoplasms, Experimental; Nucleosides; Nucleotides; Phosphotransferases; Rats; Thymidine; Thymus Gland | 1969 |
In vivo replication of normal and tumor cells: relation to cancer chemotherapy.
Topics: Animals; Autoradiography; Carcinoma, Hepatocellular; Cell Division; Deoxyuridine; DNA; DNA, Neoplasm; Female; Humans; Ileum; Liver; Liver Neoplasms; Lymphocytes; Mammary Neoplasms, Experimental; Mitosis; Neoplasms; Neoplasms, Experimental; Rats; Sarcoma, Experimental; Spleen; Thymidine; Tritium | 1969 |
Distribution of cell doubling times in in vivo human cerebral tumors.
Topics: Brain Neoplasms; Deoxyuridine; DNA; Glioblastoma; Humans; Infusions, Parenteral; Mitosis; Models, Theoretical; Thymidine; Tritium | 1969 |
Quantitative aspects of thymidine uptake into the acid-souble pool of normal and polyoma-transformed hamster cells.
Topics: Animals; Animals, Newborn; Cell Line; Cell Transformation, Neoplastic; Chromatography; Cricetinae; Culture Techniques; Cytopathogenic Effect, Viral; Deoxyuridine; Embryo, Mammalian; Idoxuridine; Phenylalanine; Polyomavirus; Thymidine; Thymidine Kinase; Tritium | 1970 |
The nucleoside-copper (II) interaction and the tautomeric forms of the nucleosides.
Topics: Chemical Phenomena; Chemistry; Copper; Cytarabine; Deoxyadenosines; Deoxyuridine; Electron Spin Resonance Spectroscopy; Nucleosides; Spectrum Analysis; Thymidine | 1971 |
Inhibition by penicillamine of DNA and protein synthesis by human bone marrow.
Topics: Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Copper; Deoxyuridine; Depression, Chemical; DNA; Formates; Humans; Ilium; In Vitro Techniques; Iron; Neoplasms; Penicillamine; Perchlorates; Protein Biosynthesis; RNA; Serine; Stereoisomerism; Thymidine; Tritium; Uridine; Zinc | 1972 |
Mitochondrial thymidine-deoxyuridine-phosphorylating activity and the replication of mitochondrial DNA.
Topics: Animals; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Centrifugation, Density Gradient; Chloramphenicol; Cycloheximide; Deoxyuridine; DNA; DNA Replication; DNA, Viral; Female; Haplorhini; HeLa Cells; Humans; Kidney; Mice; Mitochondria; Nucleic Acid Hybridization; Puromycin; Rats; Simian virus 40; Thymidine; Tritium; Uterine Cervical Neoplasms; Virus Replication | 1972 |
DNA methylation in normal and tumour virus-transformed cells in tissue culture. I. The level of DNA methylation in BHK21 cells and in BHK21 cells transformed by polyoma virus (PyY cells).
Topics: Animals; Carbon Radioisotopes; Cell Line; Cell Transformation, Neoplastic; Chromatography, Paper; Clone Cells; Cricetinae; Cytidine; Cytosine; Deoxyuridine; DNA; Kidney; Methionine; Methylation; Polyomavirus; Thymidine; Time Factors; Tritium; Uridine | 1973 |
Transport of methotrexate into normal haemopoietic cells and into leukaemic cells and its effects on DNA synthesis.
Topics: Bone Marrow; Bone Marrow Cells; Carbon Radioisotopes; Culture Techniques; Cyclic AMP; Dactinomycin; Deoxyuridine; DNA; Folic Acid; Humans; Lectins; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphocyte Activation; Methotrexate; Mitosis; Phosphodiesterase Inhibitors; Puromycin; RNA; Theophylline; Thymidine; Tritium | 1973 |
Absence of adenovirus-specific repressor in adenovirus tumour cells.
Topics: Adenoviridae; Animals; Autoradiography; Azaguanine; Carcinoma, Squamous Cell; Cell Fusion; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Dactinomycin; Deoxyuridine; Inclusion Bodies, Viral; Laryngeal Neoplasms; Mitomycins; Parainfluenza Virus 1, Human; Phenylalanine; Puromycin; Thiouracil; Thymidine; Tritium; Virus Replication | 1974 |
Pyrimidine excretion by cultured fibroblasts: effect of mutational deficiency in pyrimidine salvage enzymes.
Topics: Animals; Carbon Radioisotopes; Cell Line; Cells, Cultured; Chromatography, Thin Layer; Deoxycytidine; Deoxyuridine; Fibroblasts; Mice; Mice, Inbred Strains; Mutation; Phosphotransferases; Pyrimidines; Thymidine; Thymidine Kinase; Uracil | 1974 |
Intracellular conversions of deoxyribonucleosides by Novikoff rat hepatoma cells and effects of hydroxyurea.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Cycloheximide; Cytidine; Deamination; Deoxyadenosines; Deoxyribonucleosides; Deoxyuridine; Diphosphates; Dipyridamole; DNA, Neoplasm; Guanine Nucleotides; Hydroxyurea; Hypoxanthines; Inosine; Inosine Nucleotides; Liver Neoplasms; Neoplasms, Experimental; Phosphates; Rats; RNA, Neoplasm; Thymidine; Time Factors; Tritium | 1974 |
The deoxyribonucleoside transport systems of cultured Novikoff rat hepatoma cells.
Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Line; Cell Membrane Permeability; Cells, Cultured; Cytochalasin B; Deoxyribonucleosides; Deoxyuridine; Depression, Chemical; Dipyridamole; Fluorouracil; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Rats; Thymidine; Time Factors; Tritium | 1974 |
A comparison of the utilization of thymine and thymidine for the synthesis of DNA-thymine in Novikoff hepatoma cells.
Topics: Alkylating Agents; Carcinoma, Hepatocellular; Cells, Cultured; Deoxyadenosines; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; DNA, Neoplasm; Guanosine; Kinetics; Liver Neoplasms; Mesylates; Neoplasms, Experimental; Thymidine; Thymine; Tritium | 1974 |
Effect of 2'-deoxythymidine on experimental herpes infection.
Topics: Animals; Cricetinae; Deoxyuridine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Eye Injuries; Female; Iodine; Keratitis, Dendritic; Male; Ointments; Rabbits; Simplexvirus; Thymidine; Thymine Nucleotides; Wound Healing | 1974 |
The demonstration of protein synthesis-dependent repair replication in Escherichia coli after treatment with the mono-alkylating agent ethyl methane sulphonate.
Topics: Bacterial Proteins; Bromodeoxyuridine; Centrifugation, Density Gradient; Chloramphenicol; Deoxyuridine; DNA Repair; DNA Replication; DNA, Bacterial; Escherichia coli; Mesylates; Mitomycins; Thymidine; Tritium | 1974 |
[Thymidylate synthetase in Drosophila melanogaster].
Topics: Animals; Bromodeoxyuridine; Deoxyuridine; DNA; Drosophila; Ligases; Mutagens; Nucleotides; Thymidine; Tritium; Uracil Nucleotides | 1969 |
Utilization of deoxyribonucleosides by virulent and avirulent Pneumococci.
Topics: Bacillus; Carbon Isotopes; Deoxyuridine; DNA Replication; DNA, Bacterial; Glycoside Hydrolases; Nucleosides; Phosphotransferases; Polysaccharides, Bacterial; Streptococcus pneumoniae; Thymidine | 1970 |
Bone marrow lymphocytes: their isolation, colony-forming capacity and graft-versus-host potential. I. The isolation and characterization of subpopulations of bone marrow lymphocytes.
Topics: Animals; Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Count; Centrifugation, Density Gradient; Deoxyuridine; DNA; Femur; Graft vs Host Reaction; Iodine Isotopes; Lymphocytes; Mice; Rats; Thymidine; Tritium | 1971 |
The interaction between pyrimidine nucleosides and benzene in aqueous solution, studied by proton magnetic resonance.
Topics: Benzene; Cytidine; Deoxyuridine; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Temperature; Thymidine; Uridine | 1972 |
Letter: Nucleic acid hydrolysis. I. Isomerization and anomerization of pyrimidic deoxyribonucleosides in an acidic medium.
Topics: Deoxyribonucleosides; Deoxyuridine; Hydrolysis; Isomerism; Methods; Pyrimidine Nucleosides; Thymidine | 1974 |
The mechanisms of action of three fluorine substituted cytosine analogs: implications for cancer chemotherapy.
Topics: Antineoplastic Agents; Arabinose; Cells, Cultured; Cytarabine; Cytidine; Cytosine; Deoxyuridine; DNA; Flucytosine; Fluorine; Humans; Lymphocytes; Nucleosides; Thymidine; Tritium | 1974 |
5-Ethyl-2'-deoxyuridine: absence of effects on the chromosomes of human lymphocytes and fibroblasts in culture.
Topics: Autoradiography; Cell Division; Cells, Cultured; Chromosomes; Deoxyuridine; DNA; Fibroblasts; Humans; Idoxuridine; Lymphocytes; Thymidine; Tritium | 1974 |
Measurement of the kinetic status of bone marrow precursor cells: three cautionary tales.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Division; Cell Survival; Dactinomycin; Deoxyuridine; DNA; Evaluation Studies as Topic; Female; Idoxuridine; Iodine Radioisotopes; Kinetics; Male; Mathematics; Methods; Mice; Mice, Inbred Strains; Mitosis; Radiation Effects; Regeneration; RNA; Thymidine; Time Factors; Tritium; Uridine | 1974 |
Different action of suicidal doses of tritiated thymidine and hydroxyurea on murine haemopoietic cells.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Division; Cell Survival; Cells, Cultured; Deoxyuridine; DNA; Dose-Response Relationship, Drug; Female; Femur; Hydroxyurea; Idoxuridine; Iodine Radioisotopes; Kinetics; Mice; Mice, Inbred CBA; Spleen; Thymidine; Time Factors; Tritium | 1974 |
Excretion of thymidine and deoxyuridine by irradiated hamsters after administration of exogenous DNA.
Topics: Animals; Cricetinae; Deoxyuridine; DNA; Injections, Subcutaneous; Methods; Radiation Effects; Thymidine; Time Factors | 1974 |
Cytidine 5'-triphosphate synthetase as a target for inhibition by the antitumor agent 3-deazauridine.
Topics: Animals; Cells, Cultured; Cytidine; Cytosine Nucleotides; Deoxycytidine; Deoxyuridine; Enzyme Inhibitors; Leukemia L1210; Ligases; Liver; Mice; Thymidine; Uracil Nucleotides; Uridine | 1974 |
The role of folic acid binding proteins (FABP) in the cellular uptake of folates.
Topics: Animals; Blood; Carrier Proteins; Cell Division; Culture Media; Deoxyuridine; DNA; Female; Folic Acid; HeLa Cells; Humans; Kinetics; Lactoglobulins; Lymphocytes; Milk; Protein Binding; Tetrahydrofolates; Thymidine; Tritium | 1974 |
Biochemical abnormality of DNA synthesis of erythroblasts in acute and chronic myeloid leukemia.
Topics: Aged; Autoradiography; Bone Marrow Examination; Deoxyuridine; DNA; Erythrocytes; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mitosis; Spectrophotometry; Thymidine; Tritium; Vincristine | 1973 |
Effect ot trimethoprim on folate metabolism in human bone marrow.
Topics: Adult; Anemia, Macrocytic; Anti-Infective Agents; Bone Marrow; Culture Techniques; Deoxyuridine; Depression, Chemical; DNA; Drug Synergism; Female; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Humans; Male; Middle Aged; Pyrimidines; Thymidine; Thymine; Trimethoprim; Tritium; Vitamin B 12 Deficiency | 1973 |
[Indications for high doses of corticosteroids in the combined therapy of acute leukemie. Biochemical, morphological and cytochemical basis (author's transl)].
Topics: Adolescent; Adult; Child; Deoxyuridine; DNA; DNA Nucleotidyltransferases; Drug Therapy, Combination; Female; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Male; Prednisolone; Thymidine; Thymidine Kinase; Tritium; Vincristine | 1973 |
Stereoselective differentiation between ribonucleosides and deoxynucleosides by reaction with the copper(II) acetate dimer.
Topics: Acetates; Adenosine; Copper; Cytidine; Deoxyadenosines; Deoxyribonucleosides; Deoxyuridine; Guanosine; Inosine; Magnetic Resonance Spectroscopy; Protein Binding; Ribonucleosides; Spectrum Analysis; Thymidine | 1972 |
Changes in the deoxyribonucleoside triphosphate pools of mouse 5178Y lymphoma cells following exposure to methotrexate or 5-fluorouracil.
Topics: Adenosine Triphosphate; Animals; Cell Line; Cells, Cultured; Deoxyadenosines; Deoxycytidine; Deoxyribonucleotides; Deoxyuridine; DNA, Neoplasm; Fluorouracil; Guanosine; Leukemia, Experimental; Leukemia, Lymphoid; Methotrexate; Mice; Phosphates; Thymidine; Tritium | 1973 |
A comparative study of the relative ease of thermolytic depurination vs. depyrimidination in 2'-deoxynucleosides.
Topics: Calorimetry; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Deoxyadenosines; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; Dimethyl Sulfoxide; Guanosine; Hot Temperature; Magnetic Resonance Spectroscopy; Molecular Conformation; Purine Nucleosides; Pyrimidine Nucleosides; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Temperature; Thermodynamics; Thymidine | 1974 |
Cross-linking of complementary strands of DNA in mammalian cells by antitumour platinum compounds.
Topics: Alkylating Agents; Antineoplastic Agents; Autoradiography; Centrifugation, Density Gradient; Chlorides; Deoxyuridine; DNA; HeLa Cells; Humans; Molecular Weight; Mustard Compounds; Nucleic Acid Hybridization; Platinum; Spectrum Analysis; Thymidine; Tritium | 1972 |
DNA synthesis in chronic myelogenous leukemia cells: comparison of results in cells containing folate binding factor to replicating cells without binder.
Topics: Anemia, Hypochromic; Binding Sites; Bone Marrow Cells; Cells, Cultured; Deoxyuridine; DNA; DNA Replication; Folic Acid; Folic Acid Antagonists; Humans; Leukemia, Myeloid; Leukocytes; Lymphoma, Large B-Cell, Diffuse; Methotrexate; RNA; Thymidine; Tritium; Tuberculosis, Lymph Node; Uridine | 1972 |
Evidence for a primary association between immunoblasts and small gut.
Topics: Animals; Autoradiography; Corynebacterium; Deoxyuridine; Intestine, Small; Iodine Isotopes; Lymphocytes; Male; Mice; Rats; Sheep; Thymidine; Transplantation, Heterologous; Transplantation, Homologous; Tritium | 1972 |
A mutant of Escherichia coli defective in ribonucleosidediphosphate reductase. 1. Isolation of the mutant as a deoxyuridine auxotroph.
Topics: Alcohol Oxidoreductases; Aminohydrolases; Culture Media; Deoxycytidine; Deoxyribonucleotides; Deoxyuridine; Escherichia coli; Genetics, Microbial; Mutation; Phenotype; Ribonucleotides; Thymidine; Thymidylate Synthase; Thymine Nucleotides; Trimethoprim; Uracil Nucleotides | 1973 |
A deoxyuridine monophosphate phosphatase detected in mutants of Escherichia coli lacking alkaline phosphatase and 5'-nucleotidase.
Topics: Alkaline Phosphatase; Chromatography, Ion Exchange; Deoxyuridine; Escherichia coli; Genetics, Microbial; Molecular Biology; Mutation; Nucleotidases; Thymidine | 1973 |
In vitro methods for the assessment of cell-mediated tumor immunity.
Topics: Animals; Antigens, Neoplasm; Cell Adhesion; Cell Division; Chromium Isotopes; Deoxyuridine; Humans; Immunity, Cellular; Immunologic Techniques; Iodine Isotopes; Lymphocyte Activation; Neoplasms; Thymidine; Tritium | 1972 |
Inhibition of deoxythymidine kinase activity by the virostatic 5-ethyl-2'-deoxyuridine.
Topics: Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Deoxyuridine; Escherichia coli; Iodine; Kinetics; Mice; Mice, Inbred BALB C; Phosphotransferases; Thymidine; Tritium | 1973 |
Studies of pyrimidine deoxynucleoside metabolism in newborn mouse skin.
Topics: Animals; Animals, Newborn; Carbon Isotopes; Culture Techniques; Cytidine; Cytosine Nucleotides; Deoxyribonucleosides; Deoxyuridine; DNA; Hydrolysis; Methods; Mice; Nucleotides; Phosphotransferases; Pyrimidines; Skin; Thymidine; Thymidine Kinase; Time Factors | 1972 |
A new radioisotopic microcytotoxicity assay of cellular immunity utilizing technetium-99m.
Topics: Animals; Cytotoxicity Tests, Immunologic; Deoxyuridine; Immunity, Cellular; Iodine Isotopes; Lymph Nodes; Methods; Mice; Mice, Inbred C57BL; Sarcoma, Experimental; Technetium; Thymidine; Tritium | 1972 |
Effects of methotrexate on established cell lines of human choriocarcinoma.
Topics: Cell Line; Choriocarcinoma; Deoxyuridine; Depression, Chemical; DNA, Neoplasm; Female; Folic Acid Antagonists; Humans; Methotrexate; Neoplasm Proteins; Pregnancy; Thymidine | 1972 |
Production of migration inhibitory factor by non-dividing lymphocytes.
Topics: Cell Division; Cell Migration Inhibition; Cells, Cultured; Deoxyuridine; Humans; Light; Lymphocytes; Streptodornase and Streptokinase; Thymidine; Tritium | 1973 |
A new radioisotopic microassay of cell-mediated immunity utilizing technetium-99m labeled target cells.
Topics: Animals; Cytotoxicity Tests, Immunologic; Deoxyuridine; Immunity, Cellular; Iodine Isotopes; Isotope Labeling; Lymphocytes; Mice; Mice, Inbred C57BL; Sarcoma, Experimental; Technetium; Thymidine; Tritium | 1973 |
Determination of therapeutic index of drugs by in vitro sensitivity tests using human host and tumor cell suspensions.
Topics: Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Deoxyuridine; DNA, Neoplasm; Fluorouracil; Humans; In Vitro Techniques; Methotrexate; Neoplasms; Penicillamine; Thymidine; Time Factors; Tritium | 1973 |
Defective DNA synthesis in human megaloblastic bone marrow: effects of hydroxy-B 12 5'-deoxyadenosyl-B 12 and methyl-B 12 .
Topics: Anemia, Macrocytic; Anemia, Pernicious; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Deoxyuridine; DNA; Folic Acid; Humans; Thymidine; Thymine Nucleotides; Tritium; Vitamin B 12; Vitamin B 12 Deficiency | 1973 |
The dU suppression test using 125 I-UdR to define biochemical megaloblastosis.
Topics: Anemia, Macrocytic; Bone Marrow; Deoxyuridine; DNA; Folic Acid; Folic Acid Deficiency; Humans; In Vitro Techniques; Iodine Isotopes; Methods; Thymidine; Thymine; Tritium; Vitamin B 12; Vitamin B 12 Deficiency | 1973 |
Studies on the uptake of synthetic conjugated folates by human marrow cells.
Topics: Anemia, Macrocytic; Biological Transport; Bone Marrow; Bone Marrow Cells; Coenzymes; Deoxyuridine; DNA; Folic Acid; Glutamates; Humans; Lymphocytes; Pyrimidines; Structure-Activity Relationship; Thymidine; Tritium | 1973 |
Threshold methotrexate concentration for in vivo inhibition of DNA synthesis in normal and tumorous target tissues.
Topics: Animals; Ascites; Ascitic Fluid; Bone Marrow; Deoxyuridine; Depression, Chemical; DNA Replication; DNA, Neoplasm; Dose-Response Relationship, Drug; Duodenum; Intestinal Mucosa; Leukemia L1210; Methotrexate; Mice; Thymidine; Thymine Nucleotides; Tritium | 1973 |
Mechanism of intestinal radiosensitization by actinomycin D.
Topics: Animals; Cell Division; Dactinomycin; Deoxyuridine; DNA; Hydroxyurea; Iodine Isotopes; Jejunum; Male; Mice; Radiation Effects; Radiation-Sensitizing Agents; Thymidine; Tritium | 1973 |
5-Ethyl-2'-deoxyuridine: evidence for incorporation into DNA and evaluation of biological properties in lymphocyte cultures grown under conditions of amethopterine-imposed thymidine deficiency.
Topics: Autoradiography; Bromodeoxyuridine; Carbon Radioisotopes; Cells, Cultured; Chromosome Aberrations; Culture Media; Deoxyuridine; DNA; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Lymphocytes; Methotrexate; Mitosis; Thymidine; Time Factors | 1973 |
Differences in reutilization of thymidine in hemopoietic and lymphopoietic tissues of the normal mouse.
Topics: Animals; Autoradiography; Bone Marrow; Deoxyuridine; DNA; Female; Injections, Intravenous; Intestine, Small; Iodine Radioisotopes; Lymph Nodes; Mesentery; Mice; Models, Biological; Organ Specificity; Regression Analysis; Spectrophotometry, Ultraviolet; Spleen; Thymidine; Thymus Gland; Tritium | 1973 |
[Thymidylate synthetase activity in bone marrow cells of folic acid deflcient rats (author's transl)].
Topics: Animals; Bone Marrow; Bone Marrow Cells; Carbon Radioisotopes; Deoxyuridine; DNA; Folic Acid Deficiency; Methyltransferases; Rats; Thymidine; Thymidylate Synthase; Tritium | 1973 |
The effect of folate and folate analogs upon dihydrofolate reductase and DNA synthesis in kidneys of normal mice.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Deoxyuridine; DNA; Folic Acid; Folic Acid Antagonists; Isotope Labeling; Kidney; Male; Methotrexate; Mice; Mice, Inbred Strains; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Thymidine; Time Factors; Tritium; Ultracentrifugation; Ultrafiltration; Xanthopterin | 1974 |
The effect of DL-cysteine hydrochloride on in situ thymus cells.
Topics: Age Factors; Animals; Cysteine; Deoxyuridine; DNA; Injections, Intraperitoneal; Iodine Radioisotopes; Lymphocyte Activation; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Mitosis; Rats; Rats, Inbred Strains; Thymidine; Thymus Gland; Time Factors; Tritium | 1974 |
The effect of nucleosides on the phosphorolysis of thymidine by normal and phage-infected cells of E. coli.
Topics: Cell-Free System; Coliphages; Deoxyuridine; Escherichia coli; Nucleosides; Thymidine; Thymine; Triazines; Tritium; Uracil; Uridine | 1968 |
Studies relating to the mode of action of methotrexate. 3. Inhibition of thymidylate synthetase in tissue culture cells and in cell-free systems.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell-Free System; Chromatography, Ion Exchange; Cricetinae; Culture Techniques; Deoxyuridine; DNA; Embryo, Mammalian; Escherichia coli; Folic Acid; Histocytochemistry; Kinetics; L Cells; Leucovorin; Methotrexate; Mice; Nucleotides; RNA; Thymidine; Transferases; Tritium | 1969 |
Propagation of herpes type virus isolated from chickens with Marek's disease in Japanese quail embryo fibroblasts.
Topics: Animals; Antigens; Autoradiography; Avian Leukosis; Birds; Chickens; Culture Techniques; Deoxyuridine; DNA, Viral; Ducks; Embryo, Nonmammalian; Fibroblasts; Fluorescent Antibody Technique; Herpesviridae; Inclusion Bodies, Viral; Microscopy, Electron; Poultry Diseases; Thymidine; Tritium; Virus Cultivation | 1970 |
Effect of iododeoxyuridine upon conjugation and the fate of transferred deoxyribonucleic acid in Escherichia coli K-12.
Topics: Bacteriological Techniques; Centrifugation, Density Gradient; Cesium; Chlorides; Conjugation, Genetic; Culture Media; Deoxyuridine; DNA, Bacterial; Escherichia coli; Formaldehyde; Iodine; Molecular Biology; Nucleic Acid Denaturation; Recombination, Genetic; Thymidine; Tritium | 1971 |
Labeling of marrow cells of vitamin E-deficient monkeys by 3H-precursors of nucleic acids and protein.
Topics: Animals; Autoradiography; Bone Marrow; Bone Marrow Cells; Deoxyuridine; Erythropoiesis; Haplorhini; Hematocrit; Hemoglobinometry; Leucine; Nucleic Acids; Proteins; Thymidine; Tritium; Uridine; Vitamin E Deficiency | 1969 |
Charge-spatial models. 2. cis-and trans-3-and-4-carboxycyclohexyl phosphates and the carboxylate esters as analogs of 2'-deoxyuridine 5'-phosphate.
Topics: Chemical Phenomena; Chemistry; Cyclohexanecarboxylic Acids; Deoxyuridine; Enzyme Inhibitors; Escherichia coli; Esters; Nucleotides; Thymidine | 1971 |
Acidic hydrolysis of deoxycytidine and deoxyuridine derivatives. The general mechanism of deoxyribonucleoside hydrolysis.
Topics: Bromine; Bromodeoxyuridine; Cytidine; Deoxyribonucleosides; Deoxyuridine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mathematics; Methylation; Models, Chemical; Nucleosides; Spectrophotometry; Temperature; Thermodynamics; Thymidine; Ultraviolet Rays; Uracil | 1972 |
Studies of nonmigrating, long-lived lymphocytes in rats. I. Reactions after antigenic challenges in situ.
Topics: Animals; Antibody Formation; Antigens; Antigens, Bacterial; Autoradiography; Carbohydrates; Cattle; Cell Adhesion; Deoxyuridine; Erythrocytes; Female; Flagella; Immunization, Secondary; Immunologic Memory; Iodine Isotopes; Lymph Nodes; Lymphocytes; Polysaccharides, Bacterial; Rats; Salmonella; Serum Albumin, Bovine; Sheep; Thymidine; Tritium | 1972 |
Megaloblastic maturation masked by iron deficiency: a biochemical basis.
Topics: Anemia, Hypochromic; Anemia, Macrocytic; Bone Marrow; Culture Techniques; Deferoxamine; Deoxyuridine; DNA; Folic Acid Deficiency; Humans; Iron; Methotrexate; Thymidine; Tritium; Vitamin B 12 Deficiency | 1972 |
"Abbreviated" dinucleosides of thymidine and deoxyuridine and their photoproducts.
Topics: Deoxyuridine; Photochemistry; Thymidine | 1972 |
Effect of trimethoprim on folate-dependent DNA synthesis in human bone marrow.
Topics: Anti-Infective Agents; Bone Marrow; Culture Techniques; Deoxyuridine; DNA; Ethanol; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate; Pyrimidines; Thymidine; Trimethoprim; Tritium | 1972 |
The distribution and differentiation of lymph-borne immunoblasts after intravenous injection into syngeneic recipients.
Topics: Animals; Antigens; Autoradiography; Cell Differentiation; Cell Movement; Deoxyuridine; Intestine, Small; Iodine Isotopes; Liver; Lung; Lymph; Lymph Nodes; Lymphocytes; Male; Microscopy, Electron; Peyer's Patches; Rats; Rats, Inbred Strains; Spleen; Thoracic Duct; Thymidine; Thymus Gland; Tritium | 1972 |
Morphogenic effects of halogenated thymidine analogs on Drosophila. 3. 5-Iododeoxyuridine.
Topics: Abnormalities, Drug-Induced; Animals; Centrifugation, Density Gradient; Deoxyuridine; DNA; Drosophila; Fluorouracil; Larva; Thymidine; Tritium | 1972 |
Conformation of nucleosides. II. Dipole moments and conformation of nucleosides.
Topics: Chemical Phenomena; Chemistry, Physical; Deoxyuridine; Dioxins; Methane; Ribonucleosides; Solubility; Thymidine; Thymine; Uridine | 1972 |
Cell proliferation kinetics in goldfish acclimated to various temperatures.
Topics: Acclimatization; Animals; Autoradiography; Cyprinidae; Deoxyuridine; DNA; Hematopoietic Stem Cells; Intestinal Mucosa; Iodine Isotopes; Kidney; Kinetics; Mitosis; Temperature; Thymidine; Tritium | 1972 |
Nuclear and cytoplasmic DNA synthesis in cotton embryos: a correlated light and electron microscope autoradiographic study.
Topics: Autoradiography; Cell Nucleus; Cytoplasm; Deoxyribonucleases; Deoxyuridine; DNA; Germ Cells; Gossypium; Microscopy, Electron; Mitochondria; RNA; Thymidine; Tritium; Ultraviolet Rays | 1972 |
Antitumor activity of a folate-cleaving enzyme, carboxypeptidase G 1 .
Topics: Animals; Antineoplastic Agents; Carboxypeptidases; Carcinoma 256, Walker; Cell Division; Cell Line; Cells, Cultured; Clone Cells; Deoxyuridine; Depression, Chemical; DNA, Neoplasm; Female; Folic Acid; Folic Acid Deficiency; Humans; Injections, Intraperitoneal; Leukemia L1210; Liver; Lymphoma; Male; Mice; Mice, Inbred AKR; Mice, Inbred DBA; Mice, Inbred Strains; Neoplasms, Experimental; Rats; Sarcoma 180; Thymidine; Time Factors; Tritium | 1972 |
The effect of chemotherapeutic agents on the incorporation of DNA precursors by experimental brain tumors.
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Bone Marrow; Brain; Brain Neoplasms; Carbon Isotopes; Carmustine; Cyclohexanes; Cytarabine; Deoxyuridine; Disease Models, Animal; DNA, Neoplasm; Dose-Response Relationship, Drug; Ependymoma; Glioma; Lymph Nodes; Male; Methotrexate; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Thymidine; Tritium | 1972 |
Studies on agranulocytosis. IX. A biochemical defect in chlorpromazine-sensitive marrow cells.
Topics: Adenosine; Adult; Aged; Agranulocytosis; Bone Marrow; Bone Marrow Cells; Cell Division; Cells, Cultured; Chlorpromazine; Deoxyuridine; DNA; Female; Humans; Male; Middle Aged; Thymidine; Thymine Nucleotides; Tritium | 1971 |
Mammalian deoxynucleoside kinases. IV. Deoxythymidine kinase: purification, properties, and kinetic studies.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Ammonium Sulfate; Animals; Carbon Isotopes; Cattle; Centrifugation, Density Gradient; Chemical Precipitation; Chromatography, Gel; Cytosine Nucleotides; Deoxyribonucleosides; Deoxyuridine; Drug Stability; Guanine Nucleotides; Guanosine Triphosphate; Hot Temperature; Kinetics; Molecular Weight; Phosphotransferases; Protamines; Ribonucleosides; Streptomycin; Thymidine; Thymine Nucleotides; Thymus Gland; Tritium; Uracil Nucleotides | 1971 |
Reutilization of 5- 125 I-iodo-2'-deoxyuridine and 3 H-thymidine in regenerating liver of mice.
Topics: Animals; Autoradiography; Deoxyuridine; Female; Hepatectomy; Iodine Isotopes; Leukocytes; Liver; Liver Regeneration; Mice; Mice, Inbred Strains; Thymidine; Time Factors; Tritium | 1971 |
Studies on the conformation of nucleosides, dinucleoside monophosphates and homopolynucleotides containing uracil or thymine base residues, and ribose, deoxyribose or 2'-O-methylribose.
Topics: Chemical Phenomena; Chemistry; Circular Dichroism; Deoxyuridine; Methylation; Nucleic Acid Conformation; Ribonucleosides; Temperature; Thymidine; Thymine Nucleotides; Ultraviolet Rays; Uracil Nucleotides; Uridine | 1971 |
The mechanism of aristeromycin. I. Growth inhibition of Xanthomonas oryzae by aristeromycin.
Topics: Adenine; Adenosine; Anti-Bacterial Agents; Cytidine; Cytosine; Deoxyuridine; Guanine; Guanosine; Hypoxanthines; Inosine; Nucleosides; Thymidine; Thymine; Uracil; Uridine; Xanthines; Xanthomonas | 1971 |
Congenital familial megaloblastic anemia.
Topics: Anemia, Macrocytic; Bone Marrow; Cobalt Isotopes; Deoxyuridine; Female; Folic Acid; Hemoglobins; Humans; In Vitro Techniques; Infant; Infant, Newborn; Methods; Orotic Acid; Phosphates; Thymidine; Vitamin B 12 | 1971 |
Dihydrofolate reductase activity and deoxynucleoside incorporation into DNA of human leukocytes. Relation to methotrexate administration.
Topics: Adolescent; Adult; Child; Child, Preschool; Deoxyuridine; DNA; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Male; Methotrexate; Middle Aged; Nucleosides; Tetrahydrofolate Dehydrogenase; Thymidine | 1967 |
Coordinated changes in biochemical patterns: the effect of cytosine arabinoside and methotrexate on leukocytes from patients with acute granulocytic leukemia.
Topics: Acute Disease; Cytarabine; Deoxyuridine; DNA; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Ligases; Methotrexate; Phosphotransferases; Tetrahydrofolate Dehydrogenase; Thymidine; Thymidine Kinase | 1969 |
Treatment of leukemia with large doses of methotrexate and folinic acid: clinical-biochemical correlates.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Deoxyuridine; DNA, Neoplasm; Female; Folic Acid; Humans; Leukemia; Leukemia, Lymphoid; Male; Methotrexate; Middle Aged; Tetrahydrofolate Dehydrogenase; Thymidine; Tritium | 1969 |
Methotrexate inhibition of deoxyuridine incorporation in the skin of three day old rats.
Topics: Animals; Deoxyuridine; Depression, Chemical; DNA; Folic Acid Antagonists; Methotrexate; Rats; Skin; Thymidine; Tritium | 1971 |
Synchronization and recruitment in acute leukemia.
Topics: Adult; Antineoplastic Agents; Asparaginase; Bone Marrow; Bone Marrow Cells; Child; Culture Techniques; Cyclophosphamide; Cytarabine; Deoxyuridine; Depression, Chemical; DNA, Neoplasm; Exchange Transfusion, Whole Blood; Humans; Hydrocortisone; Kinetics; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Methotrexate; Mitosis; Thymidine; Tritium; Vincristine | 1971 |
Perturbation of generation cycle of human leukemic myeloblasts in vivo by methotrexate.
Topics: Aged; Autoradiography; Bone Marrow Examination; Deoxyuridine; DNA; Erythrocytes; Female; Hematopoietic Stem Cells; Humans; Kinetics; Leukemia, Myeloid, Acute; Leukocytes; Male; Methotrexate; Middle Aged; Mitosis; Spectrophotometry; Thymidine; Tritium; Vincristine | 1971 |
Growth rate and cell kill.
Topics: Animals; Cell Division; Cell Survival; Cells, Cultured; Deoxyuridine; DNA, Neoplasm; Drug Interactions; Humans; Leukemia L1210; Leukemia, Experimental; Methotrexate; Mice; Thymidine; Time Factors; Tritium; Uridine | 1971 |
Biochemical and pathophysiological rationale for amethopterin in psoriasis.
Topics: Administration, Oral; Autoradiography; Deoxyuridine; Epithelium; Germ Cells; Humans; Injections, Intramuscular; Methotrexate; Mitosis; Psoriasis; Skin; Thymidine; Time Factors; Tritium | 1971 |
Prediction of methotrexate responsiveness of tumors in man.
Topics: Deoxyuridine; DNA, Neoplasm; Drug Resistance; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Methotrexate; Prognosis; Tetrahydrofolate Dehydrogenase; Thymidine; Tritium | 1971 |
Radiation effects on DNA synthesis and cell division in the bone-marrow of the mouse.
Topics: Animals; Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Division; Colorimetry; Deoxyuridine; DNA; Female; Mice; Radiation Effects; Spleen; Thymidine; Tritium | 1966 |
Characteristics of "repair synthesis" in x-irradiated P388F lymphoma cells.
Topics: Autoradiography; Cell Line; Centrifugation, Density Gradient; Cesium; Culture Techniques; Deoxyuridine; DNA, Neoplasm; Humans; Hydroxyurea; Lymphoma; Radiation Effects; Thymidine; Time Factors; Tritium | 1970 |
[Influence of 5-ethyl-2'-deoxyuridine (EDU) on the regeneration of experimentally damaged cornea].
Topics: Animals; Cautery; Cell Migration Inhibition; Cornea; Corneal Injuries; Deoxyuridine; Disease Models, Animal; DNA; HeLa Cells; Rabbits; Regeneration; Thymidine; Wound Healing | 1970 |
Elevation of thymidylate synthetase activity in CCRF-CEM cells.
Topics: Cell Line; Cells, Cultured; Child; Deoxyuridine; Humans; In Vitro Techniques; Leucovorin; Leukemia, Lymphoid; Methotrexate; Methyltransferases; Thymidine; Uracil Nucleotides | 1971 |
Purification and substrate specificity of pyrimidine nucleoside phosphorylase from Haemophilus influenzae.
Topics: Arabinose; Bromodeoxyuridine; Bromouracil; Chromatography; Chromatography, DEAE-Cellulose; Cytidine; Deoxyuridine; Dithiothreitol; Drug Stability; Electrophoresis; Glycerol; Haemophilus influenzae; Hot Temperature; Kinetics; Mathematics; Nucleosides; Pentosyltransferases; Phosphates; Spectrophotometry; Thymidine; Uracil; Uridine | 1971 |
Uridine phosphorylase from rat brain: characteristics and developmental course.
Topics: Age Factors; Animals; Arsenic; Brain; Carbon Isotopes; Centrifugation; Deoxyuridine; Hot Temperature; Hydrocortisone; Hydrogen-Ion Concentration; Injections, Intraperitoneal; Injections, Subcutaneous; Liver; Nucleosides; Phosphates; Rats; Thymidine; Transferases; Uridine | 1969 |
S-phase cells of rapidly growing and resting populations. Differences in response to methotrexate.
Topics: Animals; Cell Line; Clone Cells; Culture Techniques; Deoxyuridine; DNA; Folic Acid Antagonists; Kinetics; Leukemia, Experimental; Methotrexate; Mice; Thymidine; Time Factors; Tritium | 1969 |
[The influence of antimetabolites on the multiplication of Aujeszky virus. I. Studies on 5-iodo-2-desoxyuridine (JUDR)].
Topics: Animals; Antimetabolites; Antiviral Agents; Chick Embryo; Deoxyuridine; DNA, Viral; Pseudorabies; Thymidine; Virus Replication | 1969 |
[Diminished phytohemagglutinin stimulation of human lymphocyte cultures in liver cirrhosis: studies with 3H-thymidine and I-125 desoxyuridine].
Topics: Culture Techniques; Deoxyuridine; DNA; Hepatitis; Humans; Iodine Radioisotopes; Lectins; Liver; Liver Cirrhosis; Lymphocyte Activation; Lymphocytes; Thymidine; Tissue Extracts; Tritium | 1970 |
Thymidine kinase as a determinant of the response to 5-fluoro-2'-deoxyuridine in transplantable murine leukemias.
Topics: Animals; Carbon Isotopes; Culture Techniques; Deoxyuridine; Fluorine; Leukemia, Experimental; Mice; Neoplasm Transplantation; Pyrimidines; Thymidine; Thymidine Kinase; Transferases; Uridine | 1970 |
Fluorinated pyrimidines. 38. The incorporation of 5-trifluoromethyl-2'-deoxyuridine into the deoxyribonucleic acid of vaccinia virus.
Topics: Centrifugation, Density Gradient; Cesium; Chlorides; Culture Techniques; Deoxyuridine; DNA, Viral; Fluorine; HeLa Cells; Microscopy, Electron; Potassium; Tartrates; Thymidine; Vaccinia virus; Virus Replication | 1970 |
The chemical synthesis of the 1,2,4-triazole nucleosides related to uridine,2'-deoxyuridine, thymidine, and cytidine.
Topics: Binding Sites; Deoxyuridine; Glycosides; Nucleosides; Thymidine; Triazoles; Uridine | 1970 |
Origin of thymidine kinase in adenovirus-infected human cell lines.
Topics: Adenoviridae; Aminopterin; Carcinoma; Cell Line; Culture Media; Culture Techniques; Deoxyuridine; Enzyme Induction; Female; Genetics, Microbial; Glycine; HeLa Cells; Humans; Hypoxanthines; Mouth Neoplasms; Thymidine; Thymidine Kinase; Tritium; Uterine Cervical Neoplasms; Vaccinia virus; Virus Replication | 1970 |
Fluorinated pyrimidines. XXXVII. Effects of 5-trifluoromethyl-2'-deoxyuridine on the synthesis of deoxyribonucleic acid of mammalian cells in culture.
Topics: Animals; Bromine; Carbon Isotopes; Cell Division; Cell Line; Centrifugation, Density Gradient; Cesium; Chlorides; Culture Techniques; Deoxyuridine; DNA Replication; DNA, Neoplasm; Fluorine; HeLa Cells; Iodine; Leukemia, Experimental; Mitosis; Postural Balance; Thymidine; Tritium | 1970 |
Comparison of cytotoxicity and antiviral activity of 1-beta-D-arabino-furanosyl-5-iodocytosine with related compounds.
Topics: Animals; Antiviral Agents; Culture Techniques; Cytarabine; Cytosine Nucleotides; Deoxyuridine; DNA Viruses; Herpesviridae; Iodine; Kidney; Nucleosides; Rabbits; Thymidine; Uracil; Vaccinia virus; Virus Replication | 1970 |
Lymphocyte transformation in megaloblastic anaemia: morphology and DNA synthesis.
Topics: Anemia, Macrocytic; Anemia, Pernicious; Chromosomes; Culture Techniques; Deoxyuridine; DNA; Folic Acid; Folic Acid Deficiency; Humans; Lectins; Lymphocyte Activation; Lymphocytes; Thymidine; Tritium; Vitamin B 12; Vitamin B 12 Deficiency | 1970 |
Some aspects of the role of vitamin B 12 and folic acid in DNA-thymidine sy nthesis in a neoplastic C3H mouse cell strain.
Topics: Adenine; Animals; Carbon Isotopes; Cell Line; Chromatography, Paper; Culture Media; Culture Techniques; Deoxyuridine; DNA, Neoplasm; Folic Acid; Formates; Hydroxocobalamin; Mice; Neoplasms; Stimulation, Chemical; Thymidine; Vitamin B 12 | 1971 |
Incorporation of pyrimidine deoxyribonucleosides into liver lipids and other components.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Aspartic Acid; Cell Nucleus; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Deoxyribonucleosides; Deoxyuridine; DNA; Fatty Acids; Glutamates; Glycerides; Glycerol; Glycerylphosphorylcholine; Hydrolysis; Lipids; Liver; Male; Methionine; Mice; Microsomes, Liver; Mitochondria, Liver; Nucleosides; Phosphatidylcholines; Phosphatidylethanolamines; Protein Biosynthesis; Rats; Serine; Thymidine; Thymine; Tritium | 1971 |
Release of deoxyuridine by Shope virus induced papilloma and Vx-2 carcinoma cells into the incubation medium.
Topics: Aminopterin; Animals; Carcinoma; Chromatography, Ion Exchange; Culture Media; Deoxyuridine; Neoplasms, Experimental; Nucleosides; Rats; Spectrophotometry; Thymidine; Tumor Virus Infections | 1971 |
[V. Note on nucleosides. On the deoxyribonucleic acid building block, 5-hydroxymethyl-2'-deoxyuridine as well as its alpha-anomer].
Topics: Chemical Phenomena; Chemistry; Deoxyuridine; Furans; Magnetic Resonance Spectroscopy; Nucleosides; Optical Rotatory Dispersion; Thymidine | 1967 |
Pyrimidine nucleoside metabolism in mammalian cells: an in vitro comparison of two rodent species.
Topics: Animals; Autoradiography; Carbon Isotopes; Chromatography, Paper; Cricetinae; Culture Techniques; Deoxyuridine; DNA; Liver; Nucleosides; Orotic Acid; Sciuridae; Spleen; Thymidine; Thymidine Kinase; Tritium; Uridine | 1968 |
Fish liver pyrimidine deoxynucleoside phosphorylase and deoxyribosyltransferase.
Topics: Adenine; Animals; Chromatography; Cytosine; Deoxyuridine; Electrophoresis; Glucosyltransferases; Hydrogen-Ion Concentration; Hypoxanthines; Kinetics; Liver; Mercaptoethanol; Nucleosides; Phosphates; Salmonidae; Spectrophotometry; Temperature; Thymidine; Thymine; Uracil | 1968 |
Cytology of immunologic memory. A morphologic study of lymphoid cells during the anamnestic response.
Topics: Animals; Antibody Formation; Autoradiography; Cell Differentiation; Cell Division; Deoxyuridine; DNA; Hemocyanins; Lymph Nodes; Lymphocytes; Male; Microscopy; Microscopy, Electron; Mitosis; Plasma Cells; Rats; Spleen; Thymidine; Thymus Gland; Tritium; Uridine | 1968 |
Mechanisms responsible for the low incorporation into DNA of the thymidine analogue, 5-iodo-2'-deoxyuridine.
Topics: Animals; Bone Marrow; Carbon Isotopes; Deoxyuridine; DNA; Hepatectomy; Liver; Liver Regeneration; Male; Phosphates; Rats; Spleen; Thymidine; Thymus Gland; Time Factors | 1968 |
5-Ethyldeoxyuridine, a thymidine analog: photochemical transformation.
Topics: Chromatography, Thin Layer; Deoxyuridine; Hydrogen-Ion Concentration; Light; Nucleosides; Radiation Effects; Radiochemistry; Solutions; Thymidine | 1968 |
The enzymatic mechanisms for deoxythymidine synthesis in human leukocytes. II. Comparison of deoxyribosyl donors.
Topics: Carbon Isotopes; Cell-Free System; Deoxyuridine; Glucosyltransferases; Hot Temperature; Humans; Kinetics; Leukocytes; Nucleosides; Pentosephosphates; Thymidine; Thymine; Transferases; Tritium | 1968 |
The enzymatic mechanisms for deoxythymidine synthesis in human leukocytes. 3. Inhibition of deoxythymidine phosphorylase by purines.
Topics: Allopurinol; Binding Sites; Carbon Isotopes; Cell-Free System; Deoxyuridine; Depression, Chemical; Drug Stability; Glucosyltransferases; Hot Temperature; Humans; Hypoxanthines; Kinetics; Leukocytes; Mercaptopurine; Nucleosides; Protein Denaturation; Thymidine; Thymine; Urea; Xanthines | 1968 |
Utilization of thymidine and deoxyuridine for synthesis of DNA thymidylate in irradiated testicular cells of Drosophila melanogaster.
Topics: Carbon Isotopes; Deoxyuridine; DNA; Drosophila; Male; Nucleotides; Radiation Effects; Testis; Thymidine; Tritium | 1968 |
On the poor correlation between the inhibition by methotrexate of dihydrofolate reductase and of deoxynucleoside incorporation into DNA.
Topics: Animals; Deoxyuridine; DNA, Neoplasm; Folic Acid Antagonists; In Vitro Techniques; Leukemia L1210; Leukemia, Experimental; Methotrexate; Mice; Neoplasm Transplantation; Nucleosides; Nucleotides; Thymidine | 1968 |
Deoxynucleoside-sensitive mutants of Salmonella typhimurium.
Topics: Aldehyde-Lyases; Deoxyuridine; Drug Resistance, Microbial; Genetics, Microbial; Isomerases; Nucleosides; Pentosephosphates; Pentoses; Thymidine; Thymine; Transferases; Tritium | 1968 |
Separation of ribonucleosides from deoxyribonucleosides and arabinonucleosides by thin-layer chromatography.
Topics: Arabinose; Carbon Isotopes; Chromatography, Thin Layer; Deoxyuridine; Indicators and Reagents; Nucleosides; Pentoses; Ribose; Thymidine; Tritium; Uridine | 1968 |
1-H NMR studies on deuterium-hydrogen exchange at C-5 in uridines.
Topics: Chemical Phenomena; Chemistry; Deoxyuridine; Deuterium; Hydrogen; Magnetic Resonance Spectroscopy; Methods; Nucleosides; Spectrum Analysis; Temperature; Thymidine; Uracil Nucleotides; Uridine | 1968 |
The metabolism of pyrimidine compounds by Tetrahymena pyriformis.
Topics: Animals; Carbon Isotopes; Culture Media; Deoxyuridine; DNA; Nucleosides; Nucleotides; Pyrimidines; Tetrahymena; Thymidine; Uracil | 1968 |
Defective DNA synthesis in human megaloblastic bone marrow: effects of homocysteine and methionine.
Topics: Anemia; Anemia, Macrocytic; Anemia, Pernicious; Bone Marrow; Deoxyuridine; DNA; Folic Acid Deficiency; Homocysteine; Humans; In Vitro Techniques; Methionine; Methotrexate; Thymidine; Transferases; Tritium; Vitamin B 12 Deficiency | 1969 |
Mechanism of pyrimethamine-induced megaloblastosis in human bone marrow.
Topics: Anemia, Macrocytic; Bone Marrow; Bone Marrow Diseases; Chorioretinitis; Culture Techniques; Deoxyuridine; DNA; Erythrocytes; Female; Fluorouracil; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate; Middle Aged; Nucleotides; Oxidation-Reduction; Pyrimethamine; Thymidine; Tritium | 1969 |
A clonal study of the reversible inhibition of muscle differentiation by the halogenated thymidine analog 5-bromodeoxyuridine.
Topics: Animals; Autoradiography; Bromodeoxyuridine; Cell Differentiation; Chick Embryo; Clone Cells; Culture Techniques; Deoxyuridine; DNA; Horses; Immune Sera; Microscopy, Electron; Muscles; Rats; Thymidine; Tritium | 1969 |
Spin filter culture: the propagation of mammalian cells in suspension.
Topics: Animals; Cell Line; Culture Techniques; Deoxyuridine; Filtration; Kinetics; Leukemia L1210; Ligases; Methods; Mice; Models, Biological; Tetrahydrofolate Dehydrogenase; Thymidine | 1969 |
Uncatalyzed hydrolysis of deoxyuridine, thymidine, and 5-bromodeoxyuridine.
Topics: Bromodeoxyuridine; Buffers; Chemical Phenomena; Chemistry; Deoxyuridine; Hydrogen-Ion Concentration; Kinetics; Protons; Thermodynamics; Thymidine | 1969 |
125-I-DU (5-iodo-2 -deoxyuridine) in autoradiographic studies of cell proliferation.
Topics: Animals; Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Division; Deoxyuridine; DNA; Iodine Isotopes; Megakaryocytes; Neutrophils; Rats; Thymidine; Tritium | 1966 |
Changes in nucleic acid content and distribution during cotton embryogenesis.
Topics: Autoradiography; Cell Division; Cytoplasm; Dactinomycin; Deoxyuridine; DNA; Gossypium; RNA; Spectrophotometry; Thymidine; Tritium; Uridine | 1966 |
Action of 1-beta-D-arabinofuranosyl-5-fluorocytosine on the nucleic acid metabolism and viability of HeLa cells.
Topics: Antiviral Agents; Culture Techniques; Cytarabine; Deoxyuridine; DNA; HeLa Cells; Nucleosides; Proteins; RNA; Thymidine | 1966 |
Spectrophotometric and chemical studies of 5-mercaptouracil, 5-mercaptodeoxyuridine, and their S-substituted derivatives.
Topics: Antineoplastic Agents; Antiviral Agents; Deoxyuridine; Spectrophotometry; Thymidine; Thymine; Ultraviolet Rays; Uracil | 1966 |
The role of deoxyribose 5-phosphate aldolase in the synthesis of deoxyribonucleotide in mammalian cells.
Topics: Adenine; Aldehyde-Lyases; Animals; Aspartic Acid; Carcinoma, Ehrlich Tumor; Deoxyuridine; DNA; Glycine; In Vitro Techniques; Liver; Liver Regeneration; Mice; Nucleotides; Orotic Acid; Protein Biosynthesis; Rats; RNA; Subcellular Fractions; Threonine; Thymidine; Uridine | 1966 |
Nucleosides. 3. Studies on 5-methylamino-2'-deoxyuridine as a specific antiherpes agent.
Topics: Animals; Antiviral Agents; Chick Embryo; Culture Techniques; Deoxyuridine; Herpesviridae; Humans; Thymidine; Tritium | 1966 |
Inhibition of the biosynthesis of thymidylic acid by 4-N-Hydroxy-2'-deoxycytidine in L5178Y leukemic cells.
Topics: Animals; Carbon Isotopes; Culture Techniques; Deoxyuridine; DNA, Neoplasm; Leukemia, Experimental; Mice; Nucleosides; Radiometry; Spectrophotometry; Thymidine; Tritium | 1966 |
Gas chromatography of trimethylsilylated bases and nucleosides.
Topics: Chromatography, Gas; Deoxyuridine; Magnetic Resonance Spectroscopy; Nucleosides; Purines; Pyrimidines; Spectrum Analysis; Thymidine; Uridine | 1966 |
[Excretion of thymidine, deoxyuridine and beta-aminoisobutyric acid in the rat after irradiation].
Topics: Aminoisobutyric Acids; Animals; Deoxyuridine; DNA; Male; Radiation Injuries, Experimental; Rats; Thymidine; Time Factors | 1966 |
Radionucleoside incorporation by thymidine-synchronized cells.
Topics: Autoradiography; Culture Techniques; Deoxyuridine; DNA; HeLa Cells; Thymidine; Tritium | 1967 |
Synthesis of 5-carboxy-2'-deoxyuridine.
Topics: Deoxyuridine; Oxides; Thymidine | 1967 |
The enzymatic mechanisms for deoxythymidine synthesis in human leukocytes. I. Substrate inhibition by thymine and activation by phosphate or arsenate.
Topics: Arsenicals; Cell-Free System; Deoxyuridine; Glucosyltransferases; Humans; Hydrogen-Ion Concentration; Kinetics; Leukocytes; Pentosephosphates; Phosphates; Thymidine; Thymine; Uracil | 1967 |
5-allyl-2'-deoxyuridine inhibition of nucleoside phosphorylase in HeLa cells containing mycoplasma.
Topics: Deoxyuridine; Glucosyltransferases; HeLa Cells; Mycoplasma; Nucleosides; Thymidine | 1967 |
Antifolate actions of sulfasalazine on intact lymphocytes.
Topics: Animals; Burkitt Lymphoma; Cell Line; Deoxyuridine; DNA; Folic Acid Antagonists; Formates; Lymphocytes; Rats; Serine; Sulfasalazine; Thymidine | 1981 |
On the influence of thymidine analogues on the activity of phage fd promoters in vitro.
Topics: Bacteriophages; Base Composition; Bromodeoxyuridine; Deoxyribonuclease HpaII; Deoxyuridine; DNA Restriction Enzymes; DNA-Directed RNA Polymerases; DNA, Viral; Escherichia coli; Kinetics; Operon; Structure-Activity Relationship; Thymidine | 1980 |
Uridine rescue from the lethal toxicity of 5-fluorouracil in mice.
Topics: Animals; Deoxyuridine; Fluorouracil; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; RNA; Thymidine; Uridine | 1982 |
Differential effects of folinic acid and glycine, adenosine, and thymidine as rescue agents in methotrexate-treated human cells in relation to the accumulation of methotrexate polyglutamates.
Topics: Adenosine; Deoxyuridine; DNA; Fibroblasts; Glycine; Humans; Leucovorin; Methotrexate; Polyglutamic Acid; Thymidine; Time Factors | 1982 |
Combined interaction of antiherpes substances and interferon beta on the multiplication of herpes simplex virus.
Topics: Acyclovir; Animals; Antiviral Agents; Arabinonucleosides; Cell Line; Chlorocebus aethiops; Cytopathogenic Effect, Viral; Deoxyuridine; Drug Interactions; Foscarnet; Interferon Type I; Phosphonoacetic Acid; Simplexvirus; Tegafur; Thymidine; Vidarabine Phosphate | 1982 |
Methotrexate polyglutamates in cultured human cells.
Topics: Adenosine; Cells, Cultured; Deoxyuridine; DNA Replication; Fibroblasts; Glycine; Humans; Methotrexate; Peptides; Polyglutamic Acid; Protein Binding; Tetrahydrofolate Dehydrogenase; Thymidine | 1983 |
Combined chemotherapy of cutaneous herpes simplex infection of the guinea pig.
Topics: Acyclovir; Animals; Antiviral Agents; Arabinonucleosides; Deoxyuridine; Drug Therapy, Combination; Female; Foscarnet; Guinea Pigs; Herpes Simplex; Idoxuridine; Male; Phosphonoacetic Acid; Skin Diseases, Infectious; Thymidine; Trifluridine; Vidarabine Phosphate | 1983 |
Effect of blood serum from irradiated mice on the incorporation of DNA, RNA and protein precursor in L929 cells. A sensitive assay for measuring low dose response.
Topics: Animals; Blood; Cytidine; Deoxyuridine; DNA; Female; Fibroblasts; Leucine; Mice; RNA; Thymidine | 1983 |
Interaction of 2'-halogeno-2'-deoxyuridines with the human erythrocyte nucleoside transport mechanism.
Topics: Binding, Competitive; Biological Transport, Active; Bromodeoxyuridine; Deoxyuridine; Erythrocyte Membrane; Erythrocytes; Floxuridine; Humans; Idoxuridine; Kinetics; Nucleosides; Structure-Activity Relationship; Thymidine | 1983 |
Biochemical pharmacology of the lipophilic antifolate, trimetrexate.
Topics: Animals; Cell Line; Culture Techniques; Deoxyuridine; Drug Resistance; Folic Acid; Folic Acid Antagonists; Humans; Kinetics; Leucovorin; Leukemia L1210; Lymphocytes; Methotrexate; Mice; Mice, Inbred Strains; Quinazolines; Ribonucleotides; Thymidine; Trimetrexate | 1984 |
The problem of host DNA synthesis in murine cytomegalovirus-infected cells.
Topics: Animals; Cell Line; Cell Nucleus; Cytomegalovirus; Cytoplasm; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; DNA; Mice; Phosphates; Thymidine; Uridine | 1980 |
Synthesis of 5-[(methylthio)methyl]-2'-deoxyuridine, the corresponding sulfoxide and sulfone, and their 5'-phosphates: antiviral effects and thymidylate synthetase inhibition.
Topics: Animals; Antiviral Agents; Cytopathogenic Effect, Viral; Deoxyuridine; DNA; In Vitro Techniques; Kidney; Kinetics; Lacticaseibacillus casei; Methyltransferases; Rabbits; Simplexvirus; Thymidine; Thymidylate Synthase; Vaccinia virus | 1980 |
Anti-herpes simplex virus and anti-human cell growth activity of E-5-propenyl-2'-deoxyuridine and the concept of selective protection in antivirus chemotherapy.
Topics: Antiviral Agents; Cell Division; Cells, Cultured; Deoxyuridine; Herpes Simplex; Humans; Simplexvirus; Thymidine; Thymidine Kinase | 1980 |
5-Methoxymethyldeoxyuridine-resistant mutants of herpes simplex virus type 1.
Topics: Acyclovir; Animals; Arabinonucleosides; Bromodeoxyuridine; Cell Line; Deoxyuridine; Drug Resistance, Microbial; Enzyme Induction; Guanine; Mice; Mutation; Phosphonoacetic Acid; Simplexvirus; Thymidine; Thymidine Kinase | 1981 |
Antiherpes activity of [E]-5-(1-propenyl)-2'-deoxyuridine and 5-(1-propenyl)-1-beta-D-arabinofuranosyluracil.
Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Arabinonucleosides; Cell Division; Cell Line; Chlorocebus aethiops; Deoxyuridine; DNA; DNA, Viral; Guinea Pigs; Herpes Simplex; Phosphorylation; Simplexvirus; Thymidine; Uridine; Viral Plaque Assay | 1981 |
Alterations in substrate specificity and physicochemical properties of deoxythymidine kinase of a drug-resistant herpes simplex virus type 1 mutant.
Topics: Arabinonucleosides; Blood; Bromodeoxyuridine; Deoxyuridine; Drug Resistance, Microbial; Enzyme Induction; Hot Temperature; Mutation; Phosphorylation; Simplexvirus; Substrate Specificity; Thymidine; Thymidine Kinase | 1983 |
Reactions of the hydrated electron with pyrimidine nucleosides halogenated at the sugar moiety: e.s.r. and spin-trapping with 2-methyl-2-nitrosopropane.
Topics: Deoxyuridine; Electron Spin Resonance Spectroscopy; Nitroso Compounds; Spin Labels; Thymidine | 1983 |
Effects of leucovorin and methylcobalamin with N2O anesthesia.
Topics: Bone Marrow; Deoxyuridine; DNA; Folic Acid; Humans; Leucovorin; Nitrous Oxide; Thymidine; Time Factors; Vitamin B 12 | 1984 |
Folate levels and deoxyuridine suppression tests in protein-energy malnutrition.
Topics: Bone Marrow; Child, Preschool; Deoxyuridine; DNA; Erythrocytes; Erythropoiesis; Folic Acid; Humans; Infant; Kwashiorkor; Protein-Energy Malnutrition; Thymidine; Vitamin B 12 | 1983 |
[Regulation of enzyme activities involved in pyrimidine synthesis and its application to cancer chemotherapy].
Topics: Administration, Oral; Animals; Deoxyuridine; Dihydrouracil Dehydrogenase (NAD+); DNA, Neoplasm; Drug Synergism; Fluorouracil; Neoplasms, Experimental; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Pentosyltransferases; Phosphorylation; Pyrimidines; Sarcoma, Yoshida; Tegafur; Thymidine; Thymine; Uracil; Uridine | 1984 |
Biochemical mechanisms in the Killmann experiment: critique of the deoxyuridine suppression test.
Topics: Deoxyribonucleosides; Deoxyuridine; DNA; Floxuridine; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Methotrexate; Phytohemagglutinins; Thymidine; Thymidine Kinase; Thymine Nucleotides | 1980 |
Oxygenation of a carbinol carbon in the pyrimidine deoxyribonucleoside 2'-hydroxylase reaction.
Topics: Arabinofuranosyluracil; Catalysis; Deoxyuridine; Mixed Function Oxygenases; Neurospora crassa; Oxidation-Reduction; Thymidine | 1981 |
Modulation of anti-metabolite effects. Effects of thymidine on the efficacy of the quinazoline-based thymidylate synthetase inhibitor, CB3717.
Topics: Animals; Antimetabolites, Antineoplastic; Cells, Cultured; Deoxyuridine; Folic Acid; Leukemia L1210; Male; Methyltransferases; Mice; Mice, Inbred DBA; Quinazolines; Thymidine; Thymidylate Synthase | 1984 |
Dipyridamole inhibits reversion by thymidine of methotrexate effect and increases drug uptake in Sarcoma 180 cells.
Topics: Animals; Biological Transport; Deoxycytidine; Deoxyuridine; Dipyridamole; DNA Replication; Drug Antagonism; Kinetics; Methotrexate; Mice; Sarcoma 180; Thymidine; Thymine Nucleotides | 1984 |
Normal deoxyuridine-suppression test in folate deficiency.
Topics: Bone Marrow; Deoxyuridine; False Negative Reactions; Folic Acid Deficiency; Humans; Male; Thymidine | 1984 |
Thymidylate synthetase-deficient mouse FM3A mammary carcinoma cell line as a tool for studying the thymidine salvage pathway and the incorporation of thymidine analogues into host cell DNA.
Topics: Animals; Cell Division; Cell Line; Deoxyuridine; DNA, Neoplasm; Mammary Neoplasms, Experimental; Methyltransferases; Mice; Mice, Inbred C3H; Thymidine; Thymidine Kinase; Thymidylate Synthase; Uridine Kinase | 1984 |
Strategies for the measurement of the inhibitory effects of thymidine analogs on the activity of thymidylate synthase in intact murine leukemia L1210 cells.
Topics: Animals; Deoxycytidine; Deoxyuridine; DNA; Leukemia L1210; Methyltransferases; Mice; Thymidine; Thymidylate Synthase | 1984 |
Synthesis and biological properties of some cyclic phosphotriesters derived from 2'-deoxy-5-fluorouridine.
Topics: Animals; Antimetabolites, Antineoplastic; Bromodeoxyuridine; Deoxycytidine; Deoxyuridine; Drug Resistance; Indicators and Reagents; Leukemia L1210; Mice; Organophosphorus Compounds; Structure-Activity Relationship; Thymidine; Thymidine Monophosphate | 1984 |
Human tissues degrade uridine much less than thymidine. Possible consequence for 5-fluorouracil therapy.
Topics: Animals; Deoxyuridine; Fluorouracil; Humans; In Vitro Techniques; Liver; Mice; Models, Biological; Pentosyltransferases; Pyrimidine Phosphorylases; Rats; Spleen; Thymidine; Tissue Distribution; Uridine | 1984 |
Derangement of DNA synthesis in erythroleukaemia. Normal deoxyuridine suppression and impaired thymidine incorporation in bone marrow culture.
Topics: Adolescent; Adult; Anemia, Megaloblastic; Bone Marrow; Cells, Cultured; Deoxyuridine; DNA; Female; Folic Acid Deficiency; Humans; Leukemia, Erythroblastic, Acute; Male; Methotrexate; Middle Aged; Thymidine; Vitamin B 12 Deficiency | 1980 |
Inhibition of thymidylate synthase by hydroxyurea in rapidly proliferating P815 mastocytoma cells.
Topics: Animals; Deoxycytidine; Deoxyuridine; DNA, Neoplasm; Hydroxyurea; Mast-Cell Sarcoma; Methyltransferases; Mice; Thymidine; Thymidylate Synthase | 1982 |
SCE induction is proportional to substitution in DNA for thymidine by CldU and BrdU.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cricetinae; Cricetulus; Crossing Over, Genetic; Deoxyuridine; DNA; Female; Kinetics; Ovary; Sister Chromatid Exchange; Thymidine | 1983 |
Effects of therapeutic drugs on lymphocyte transformation.
Topics: Deoxyuridine; Drug Therapy; Humans; In Vitro Techniques; Lymphocyte Activation; Pharmacology; Thymidine | 1983 |
Proliferation of subependymal cells in the adult primate CNS: differential uptake of DNA labelled precursors.
Topics: Animals; Astrocytes; Autoradiography; Cell Differentiation; Cell Nucleus; Cerebral Ventricles; Deoxyuridine; DNA; Ependyma; Macaca mulatta; Male; Microscopy, Electron; Mitosis; Neurons; Rats; Rats, Inbred Strains; Thymidine | 1983 |
Thymidine and methionine syntheses in pregnant rats exposed to nitrous oxide.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Deoxyuridine; Female; Methionine; Nitrous Oxide; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains; Thymidine | 1983 |
Isolation of tumor cells from patients with osteosarcoma and analysis of their sensitivity to methotrexate.
Topics: Cell Separation; Cells, Cultured; Deoxyuridine; DNA; Drug Resistance; Humans; Hypoxanthines; Lung Neoplasms; Methotrexate; Osteosarcoma; Stimulation, Chemical; Thymidine | 1981 |
Biochemical control of high-dose methotrexate/Leucovorin rescue therapy.
Topics: Bone Marrow; Bone Marrow Cells; Deoxyuridine; DNA; Humans; Leucovorin; Methotrexate; Neoplasms; Thymidine; Thymidine Kinase | 1980 |
The intracellular mechanism of action of metoprine (DDMP).
Topics: Animals; Cell Survival; Cells, Cultured; Deoxyuridine; Dose-Response Relationship, Drug; Drug Resistance; Folic Acid Antagonists; Leucovorin; Leukemia L1210; Methotrexate; Mice; Purines; Pyrimethamine; Pyrimidines; Thymidine | 1980 |
Effect of excess folates and deoxyinosine on the activity and site of action of 5-fluorouracil.
Topics: Animals; Carcinoma; Cell Line; Deoxyribonucleosides; Deoxyribose; Deoxyuridine; Drug Synergism; Fluorouracil; Humans; Inosine; Leucovorin; Mice; Sarcoma, Experimental; Thymidine; Thymidylate Synthase | 1981 |
Megaloblastic change is a feature of colonies derived from an early erythroid progenitor (BFU-E) stimulated by monocytes in culture.
Topics: Bone Marrow Cells; Cell Division; Cells, Cultured; Deoxyuridine; Erythrocytes, Abnormal; Hematopoietic Stem Cells; Humans; Lymphocytes, Null; Megaloblasts; Monocytes; T-Lymphocytes; Thymidine; Time Factors | 1981 |
Purine nucleoside analogues inhibit the repair of radiation-induced potentially lethal damage in mammalian cells in culture.
Topics: Animals; Cells, Cultured; Cricetinae; Cricetulus; Deoxycytidine; Deoxyguanosine; Deoxyuridine; Dideoxynucleosides; DNA Repair; Dose-Response Relationship, Drug; Purine Nucleosides; Thymidine; Vidarabine | 1982 |
Interaction of an Escherichia coli mutator gene with a deoxyribonucleotide effector.
Topics: Culture Media; Deoxycytidine; Deoxyuridine; Escherichia coli; Genes; Mutation; Thymidine | 1980 |
[Radiational basis and practice of the citrovorum factor (Leucovorin) protection after high-dose methotrexate therapy. High-dose methotrexate/leucovorin].
Topics: Bone Marrow; Deoxyuridine; DNA; Dose-Response Relationship, Drug; Humans; Leucovorin; Lymphocytes; Methotrexate; Thymidine | 1980 |
5-Methyltetrahydrofolate related enzymes and DNA polymerase alpha activities in bone marrow cells from patients with vitamin B12 deficient megaloblastic anemia.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; 5,10-Methylenetetrahydrofolate Reductase (FADH2); Adult; Aged; Alcohol Oxidoreductases; Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow; Bone Marrow Cells; Deoxyuridine; DNA Polymerase II; DNA-Directed DNA Polymerase; Female; Folic Acid; Humans; Hydroxocobalamin; Leucovorin; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Tetrahydrofolates; Thymidine; Vitamin B 12; Vitamin B 12 Deficiency | 1982 |
Metabolism of deoxyuridine in rabbit brain.
Topics: Aging; Animals; Animals, Newborn; Brain; Carbon Radioisotopes; Deoxyuridine; In Vitro Techniques; Kinetics; Rabbits; Radioisotope Dilution Technique; Sucrose; Thymidine; Tritium | 1982 |
Localization and mechanism of thymidine transport in the central nervous system.
Topics: Animals; Blood-Brain Barrier; Brain; Carbon Radioisotopes; Cattle; Cerebrovascular Circulation; Deoxyuridine; Rabbits; Radioisotope Dilution Technique; Rats; Rats, Inbred Strains; Species Specificity; Sucrose; Thymidine; Tritium | 1982 |
Abnormal deoxyuridine suppression test in congenital methylmalonic aciduria-homocystinuria without megaloblastic anemia: divergent biochemical and morphological bone marrow manifestations of disordered cobalamin metabolism in man.
Topics: Adolescent; Adult; Anemia, Megaloblastic; Bone Marrow; Deoxyuridine; Homocystinuria; Humans; Male; Metabolism, Inborn Errors; Methylmalonic Acid; Tetrahydrofolates; Thymidine; Vitamin B 12 | 1982 |
In vitro synthesis of macromolecules in human colostral cells.
Topics: Amino Acids; Cells, Cultured; Colostrum; Deoxyuridine; Female; Humans; Immunoglobulins; In Vitro Techniques; Macromolecular Substances; Muramidase; Phytohemagglutinins; Thymidine; Time Factors | 1982 |
[3H]thymidine labels less than half of the DNA-synthesizing cells in the mouse tumour, carcinoma NT.
Topics: Adenocarcinoma; Animals; Cell Division; Deoxyuridine; DNA, Neoplasm; Female; Idoxuridine; Male; Mice; Mice, Inbred CBA; Mitosis; Neoplasms, Experimental; Thymidine | 1982 |
Nucleoside transport in choroid plexus: mechanism and specificity.
Topics: Animals; Biological Transport; Choroid Plexus; Deoxyuridine; Kinetics; Nucleosides; Rabbits; Structure-Activity Relationship; Thioinosine; Thymidine; Tritium | 1982 |
Characteristic abnormality of deoxyribonucleoside triphosphate metabolism in megaloblastic anemia.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow; Deoxyribonucleosides; Deoxyuridine; Humans; Methotrexate; Thymidine; Thymine Nucleotides | 1982 |
Erythrocyte aging changes evaluated by the deoxyuridine suppression test.
Topics: Adult; Aged; Bone Marrow; Deoxyuridine; DNA; Erythrocyte Aging; Erythrocyte Indices; Folic Acid Deficiency; Humans; Male; Middle Aged; Thymidine; Uridine; Vitamin B 12 Deficiency | 1982 |
Failure of 5-fluorouracil and methotrexate to destroy the reproductive integrity of a human breast cancer cell line (MCF-7) growing in vitro.
Topics: Breast Neoplasms; Cell Division; Cell Line; Cell Survival; Clone Cells; Deoxyuridine; DNA, Neoplasm; Dose-Response Relationship, Drug; Fluorouracil; Humans; Male; Methotrexate; Thymidine | 1981 |
Catabolism of thymidine in human blood platelets: purification and properties of thymidine phosphorylase.
Topics: Blood Platelets; Cytoplasm; Deoxyuridine; Humans; In Vitro Techniques; Molecular Weight; Pentosyltransferases; Substrate Specificity; Thymidine; Thymidine Phosphorylase | 1981 |
Radioimmunoassays of plasma thymidine, uridine, deoxyuridine, and cytidine/deoxycytidine.
Topics: Animals; Cytidine; Deoxycytidine; Deoxyuridine; Immune Sera; Radioimmunoassay; Thymidine; Uridine | 1981 |
The effect of folate analogues on the thymidine utilization by human and rat marrow cells and the effect on the deoxyuridine suppression test.
Topics: Anemia, Megaloblastic; Animals; Bone Marrow; Deoxyuridine; Folic Acid; Humans; Male; Rats; Rats, Inbred Strains; Thymidine; Vitamin B 12 | 1981 |
An antifolate-induced lesion in newly synthesized DNA.
Topics: Cell Line; Cell Survival; Deoxyuridine; DNA; Folic Acid Antagonists; Humans; Methotrexate; Molecular Weight; Pyrimethamine; Thymidine | 1980 |
Congenital methylmalonic aciduria--homocystinuria with megaloblastic anemia: observations on response to hydroxocobalamin and on the effect of homocysteine and methionine on the deoxyuridine suppression test.
Topics: Anemia, Megaloblastic; Deoxyuridine; DNA; Female; Homocysteine; Homocystinuria; Humans; Hydroxocobalamin; Infant; Infant, Newborn; Malonates; Methionine; Methylmalonic Acid; Myoclonus; Thymidine | 1980 |
Inactivation of methionine synthase by nitrous oxide.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Bone Marrow; Brain; Deoxyuridine; DNA Replication; Homocystine; Liver; Methyltransferases; Nitrous Oxide; Rats; Thymidine | 1980 |
Individual changes of DNA catabolite excretion in the course of antitumor therapy of Hodgkin's disease.
Topics: Cyclophosphamide; Deoxycytidine; Deoxyuridine; Hodgkin Disease; Humans; Prednisone; Procarbazine; Thymidine | 1980 |
The induction of functional vitamin B-12 deficiency in rats by exposure to nitrous oxide.
Topics: Animals; Bone Marrow; Deoxyuridine; Disease Models, Animal; DNA; Female; Folic Acid; Formyltetrahydrofolates; Nitrous Oxide; Rats; Thymidine; Vitamin B 12; Vitamin B 12 Deficiency | 1980 |
In vitro DNA synthesis by bone marrow cells and PHA-stimulated lymphocytes. Suppression by nonradioactive thymidine of the incorporation of 3H-deoxyuridine into DNA: enhancement of incorporation when inadequate vitamin B12 or folate is corrected.
Topics: Bone Marrow; Cells, Cultured; Deoxyuridine; DNA; Folic Acid; Folic Acid Deficiency; Humans; Lymphocytes; Phytohemagglutinins; Thymidine; Vitamin B 12; Vitamin B 12 Deficiency | 1980 |
Synthesis of DNA as shown by the deoxyuridine suppression test is normal in the vitamin B12-deficient fruit bat (Rosettus Aegyptiacus).
Topics: Animals; Bone Marrow; Cells, Cultured; Chiroptera; Deoxyuridine; DNA; Folic Acid; Lymphocytes; Methotrexate; Thymidine; Vitamin B 12; Vitamin B 12 Deficiency | 1980 |
Identification of cytidine deaminase as inhibitor of granulocyte-macrophage colony formation.
Topics: Animals; Azacitidine; Bone Marrow Cells; Cell Division; Cytarabine; Cytidine Deaminase; Deoxycytidine; Deoxyuridine; DNA; Female; Granulocytes; Hematopoietic Stem Cells; Macrophages; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Thymidine | 1994 |
Kinetics and mechanism of photocycloaddition of deoxyuridines to 2,3-dimethyl-2-butene.
Topics: Alkenes; Chemical Phenomena; Chemistry, Physical; Deoxyuridine; Indicators and Reagents; Kinetics; Photochemistry; Quantum Theory; Thymidine | 1995 |
Cobalamin-dependent metabolism in chronic myelogenous leukemia determined by deoxyuridine suppression test and the formiminoglutamic acid and methylmalonate excretion in urine.
Topics: Adolescent; Adult; Aged; Bone Marrow; Bone Marrow Cells; Deoxyuridine; Female; Formiminoglutamic Acid; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Malonates; Methotrexate; Middle Aged; Tetrahydrofolates; Thymidine; Tritium; Vitamin B 12 | 1995 |
Nucleoside 2-deoxyribosyltransferase. Pre-steady-state kinetic analysis of native enzyme and mutant enzyme with an alanyl residue replacing Glu-98.
Topics: Adenine; Alanine; Deoxyadenosines; Deoxyuridine; Fluorescence; Glutamic Acid; Kinetics; Mutation; Pentosyltransferases; Structure-Activity Relationship; Thymidine | 1995 |
Augmentation of 5-fluoro-2'-deoxyuridine cytotoxicity by 5-phenethyl-2'-deoxyuridine in human gastric cancer cells in culture.
Topics: Carbon Radioisotopes; Deoxyuridine; DNA, Neoplasm; Drug Synergism; Floxuridine; Humans; Nucleosides; Nucleotides; RNA, Neoplasm; Stomach Neoplasms; Thymidine; Tritium; Tumor Cells, Cultured; Uridine | 1994 |
Analysis of the thymidine kinase of a herpes simplex virus type 1 isolate that exhibits resistance to (E)-5-(2-bromovinyl)-2'-deoxyuridine.
Topics: Acyclovir; Amino Acid Sequence; Antiviral Agents; Base Sequence; Binding Sites; Bromodeoxyuridine; Deoxyuridine; Drug Resistance, Microbial; Herpesvirus 1, Human; Humans; Kinetics; Molecular Sequence Data; Phosphonoacetic Acid; Phosphorylation; Point Mutation; Sequence Analysis, DNA; Thymidine; Thymidine Kinase; Vidarabine | 1994 |
Determination of substituent effects on the proton affinities of natural nucleosides by the kinetic method.
Topics: Deoxyuridine; Kinetics; Nucleosides; Protons; Spectrometry, Mass, Fast Atom Bombardment; Thymidine | 1994 |
Lack of stereospecificity of suid pseudorabies virus thymidine kinase.
Topics: Binding, Competitive; Deoxyadenosines; Deoxyguanosine; Deoxyuridine; Herpesvirus 1, Suid; Nucleosides; Phosphorylation; Stereoisomerism; Substrate Specificity; Thymidine; Thymidine Kinase | 1993 |
Cytofluorometric assay for the determination of thymidine uptake and phosphorylation in living cells.
Topics: Cell Count; Cell Line; Deoxyuridine; DNA; Flow Cytometry; Fluorescent Dyes; Furans; Phosphorylation; Thymidine; Thymidine Kinase | 1993 |
Flow cytometric analysis of two incorporated halogenated thymidine analogues and DNA in a mouse mammary tumor grown in vivo.
Topics: Animals; Cell Separation; Deoxyuridine; DNA; Female; Flow Cytometry; Fluorescent Antibody Technique; Idoxuridine; Mammary Neoplasms, Experimental; Mice; Mice, Mutant Strains; Propidium; Sensitivity and Specificity; Thymidine | 1993 |
[Synthesis and biological properties of pyrimidine 2'-deoxynucleosides modified by a residue of quinaldic acid].
Topics: Animals; Antineoplastic Agents; Cell Division; Chickens; Deoxyuridine; DNA; Female; Humans; Nucleic Acid Conformation; Ovarian Neoplasms; Quinolines; Thymidine; Tumor Cells, Cultured | 1995 |
Reaction of epichlorohydrin with 2'-deoxynucleosides: characterization of adducts.
Topics: Chromatography, High Pressure Liquid; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Deoxyribonucleosides; Deoxyuridine; DNA Adducts; Environmental Pollution; Epichlorohydrin; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Occupational Exposure; Thymidine | 1996 |
Observation and prevention of an artefactual formation of oxidized DNA bases and nucleosides in the GC-EIMS method.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenine; Artifacts; Chromatography, High Pressure Liquid; Cytosine; Deoxyadenosines; Deoxyguanosine; Deoxyuridine; DNA; Gas Chromatography-Mass Spectrometry; Hydrolysis; Oxidation-Reduction; Sensitivity and Specificity; Thymidine | 1996 |
Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2.
Topics: Amino Acid Sequence; Base Sequence; Chromosome Mapping; Cloning, Molecular; Deoxycytidine; Deoxycytidine Kinase; Deoxyuridine; DNA, Complementary; Humans; Molecular Sequence Data; Phosphotransferases (Alcohol Group Acceptor); Polymerase Chain Reaction; Sequence Alignment; Thymidine; Thymidine Kinase | 1997 |
Relaxed enantioselectivity of human mitochondrial thymidine kinase and chemotherapeutic uses of L-nucleoside analogues.
Topics: Binding, Competitive; Bromodeoxyuridine; Cyclopentanes; Cytosol; Deoxycytidine; Deoxycytidine Kinase; Deoxyuridine; HeLa Cells; Humans; Mitochondria; Phosphorylation; Stereoisomerism; Substrate Specificity; Thymidine; Thymidine Kinase | 1997 |
Synthesis of 6-methyl[11C]-2'-deoxyuridine and evaluation of its in vivo distribution in Wistar rats.
Topics: Animals; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Deoxyuridine; Isotope Labeling; Male; Radiopharmaceuticals; Rats; Rats, Wistar; Thymidine; Tissue Distribution; Tomography, Emission-Computed | 1997 |
Structure and dynamics of human interphase chromosome territories in vivo.
Topics: Bromodeoxyuridine; Carbocyanines; Cell Nucleus; Chromosome Mapping; Chromosomes, Human; Deoxyuracil Nucleotides; Deoxyuridine; DNA Replication; Fibroblasts; Fluorescent Dyes; HeLa Cells; Humans; Idoxuridine; Interphase; Microscopy, Fluorescence; Neuroblastoma; Thymidine; Tumor Cells, Cultured | 1998 |
DNA modifications by the mutagen glyoxal: adduction to G and C, deamination of C and GC and GA cross-linking.
Topics: Cytosine; Deamination; Deoxycytidine; Deoxyguanosine; Deoxyuridine; DNA Adducts; Glyoxal; Guanine; Single-Strand Specific DNA and RNA Endonucleases; Thymidine | 1998 |
5-(1-propargylamino)-2'-deoxyuridine (UP): a novel thymidine analogue for generating DNA triplexes with increased stability.
Topics: Deoxyuridine; DNA; DNA Footprinting; Thymidine; Ultraviolet Rays | 1999 |
Hammerhead ribozyme mechanism: a ribonucleotide 5' to the substrate cleavage site is not essential.
Topics: Deoxyuridine; Hydrolysis; Kinetics; Ribonucleotides; RNA, Catalytic; Structure-Activity Relationship; Substrate Specificity; Thymidine | 1999 |
Balb/c mice as a preclinical model for raltitrexed-induced gastrointestinal toxicity.
Topics: Animals; Antimetabolites, Antineoplastic; Deoxyuridine; Diarrhea; Digestive System; Dose-Response Relationship, Drug; Folic Acid; Intestinal Mucosa; Intestine, Large; Intestine, Small; Male; Maximum Tolerated Dose; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Quinazolines; Thiophenes; Thymidine; Thymidylate Synthase; Weight Loss | 2000 |
Cloning and characterization of full-length mouse thymidine kinase 2: the N-terminal sequence directs import of the precursor protein into mitochondria.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Chromatography, Affinity; Chromatography, Gel; Cloning, Molecular; Deoxycytidine; Deoxyuridine; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Library; Humans; Kinetics; Mice; Mitochondria; Mitochondria, Liver; Molecular Sequence Data; Phosphorylation; Protein Biosynthesis; Rats; Recombinant Proteins; RNA, Messenger; Sequence Analysis, Protein; Thymidine; Thymidine Kinase; Tissue Distribution | 2000 |
Some aspects of the role of vitamin B12 in nucleic acid synthesis in a neoplastic C3H mouse cell strain. I. Growth studies.
Topics: Adenine; Adenosine; Animals; Cell Division; Cytidine; Deoxyadenosines; Deoxycytidine; Deoxyuridine; DNA, Neoplasm; Folic Acid; Guanine; Mice; Nucleic Acid Precursors; Nucleosides; Pyrimidines; Thymidine; Tumor Cells, Cultured; Uridine; Vitamin B 12 | 1970 |
Some aspects of the role of vitamin B12 in nucleic acid synthesis in a neoplastic C3H mouse cell strain. II. Incorporation of precursors.
Topics: Adenine; Animals; Carbon Radioisotopes; Cytidine; Deoxycytidine; Deoxyuridine; DNA, Neoplasm; Mice; Nucleic Acid Precursors; Nucleosides; Thymidine; Tumor Cells, Cultured; Uridine; Vitamin B 12 | 1970 |
The Escherichia coli tRNA-guanine transglycosylase can recognize and modify DNA.
Topics: Base Sequence; Catalysis; Deoxyuridine; DNA; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Kinetics; Molecular Sequence Data; Nucleic Acid Conformation; Oligonucleotides; Pentosyltransferases; Protein Binding; RNA; Thymidine; Uracil | 2002 |
5-Bromo (or chloro)-6-azido-5,6-dihydro-2' -deoxyuridine and -thymidine derivatives with potent antiviral activity.
Topics: Antiviral Agents; Azides; Chemical Phenomena; Chemistry, Physical; Deoxyuridine; Humans; Structure-Activity Relationship; Thymidine; Viral Plaque Assay; Viruses | 2002 |
One-pot two-step enzymatic coupling of pyrimidine bases to 2-deoxy-D-ribose-5-phosphate. A new strategy in the synthesis of stable isotope labeled deoxynucleosides.
Topics: Catalysis; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; Dihydroxyacetone Phosphate; Escherichia coli; Isotope Labeling; Magnetic Resonance Spectroscopy; Molecular Structure; Organisms, Genetically Modified; Phosphotransferases; Pyrimidines; Ribosemonophosphates; Saccharomyces cerevisiae; Thymidine; Thymidine Phosphorylase; Triose-Phosphate Isomerase; Uracil | 2002 |
Elevated plasma deoxyuridine in patients with thymidine phosphorylase deficiency.
Topics: Base Sequence; Biochemistry; Deoxyuridine; Dose-Response Relationship, Drug; Humans; Kinetics; Molecular Sequence Data; Mutation; Nucleosides; Point Mutation; Reference Values; Substrate Specificity; Thymidine; Thymidine Phosphorylase; Time Factors | 2003 |
Microwave-assisted synthesis of O'-adamantylated uracil-derived nucleosides.
Topics: Adamantane; Deoxyuridine; Hot Temperature; HSP70 Heat-Shock Proteins; Microwaves; Molecular Chaperones; Nucleosides; Saccharomyces cerevisiae Proteins; Thymidine; Uracil; Zidovudine | 2003 |
Synthesis of a novel aldehyde: 4-O-methyl-5-formylmethyl-2'-deoxyuridine.
Topics: Aldehydes; Deoxyuridine; Prodrugs; Thymidine | 2003 |
Growth inhibition of a human tumor cell strain by 5-fluoro-2-deoxyuridine: time parameters for subsequent reversal by thymidine.
Topics: Animals; Antineoplastic Agents; Deoxyuridine; Humans; Neoplasms, Experimental; Nucleosides; Nucleotides; Thymidine | 1959 |
Effects of uracil and thymidine on the development of resistance to 5-fluorouracil in Pediococcus cerevisiae.
Topics: Deoxyuridine; Fluorouracil; Pediococcus; Thymidine; Uracil | 1963 |
ACCUMULATION OF ACID-SOLUBLE NUCLEIC ACID PRECURSORS IN HELA CELLS INHIBITED BY 5-FLUORO-2'-DEOXYURIDINE.
Topics: Deoxyuridine; DNA; Floxuridine; HeLa Cells; Humans; Nucleic Acid Precursors; Nucleosides; Pharmacology; Research; RNA; Thymidine; Tissue Culture Techniques | 1963 |
DEVELOPMENTAL CHANGES IN THE INCORPORATION OF 5-IODO-DEOXYURIDINE BY THE EMBRYO OF ARBACIA PUNCTULATA.
Topics: Animals; Arbacia; Deoxyuridine; Echinodermata; Embryo, Mammalian; Embryo, Nonmammalian; Idoxuridine; Iodine Isotopes; Metabolism; Ovum; Research; Thymidine | 1964 |
EFFECT OF DEOXYURIDINE ON INCORPORATION OF TRITIATED THYMIDINE: DIFFERENCE BETWEEN NORMOBLASTS AND MEGALOBLASTS.
Topics: Anemia; Anemia, Pernicious; Autoradiography; Bone Marrow; Bone Marrow Examination; Deoxyuridine; Erythroblasts; Erythropoiesis; Humans; Megaloblasts; Metabolism; Thymidine; Tritium; Uracil Nucleotides | 1964 |
SPECIFICITY OF MOUSE URIDINE PHOSPHORYLASE. CHROMATOGRAPHY, PURIFICATION, AND PROPERTIES.
Topics: Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Chromatography; Deoxyuridine; Electrophoresis; Escherichia coli; Glucosyltransferases; Intestines; Liver; Mice; Neoplasms, Experimental; Nucleosides; Research; Thymidine; Uridine; Uridine Phosphorylase | 1964 |
THE EFFECT OF NATURAL AND UNNNATURAL PYRIMIDINES AND PYRIMIDINE NUCLEOSIDES ON THE PHOSPHOROLYSIS OF 5-IODODEOXYURIDINE BY MOUSE LIVER EXTRACT.
Topics: Animals; Chromatography; Deoxyuridine; Floxuridine; Fluorouracil; Idoxuridine; Iodine Isotopes; Liver; Liver Extracts; Metabolism; Mice; Nucleosides; Pharmacology; Phosphotransferases; Pyrimidine Nucleosides; Pyrimidines; Research; Thymidine; Thymine; Uracil | 1964 |
[TOLERANCE AND ACTIVITY OF 5-IODO-2'-DEOXYURIDINE IN OPHTHALMOLOGY].
Topics: Adrenal Cortex Hormones; Deoxyuridine; Drug Therapy; Idoxuridine; Keratitis; Keratitis, Dendritic; Nucleotides; Ophthalmic Solutions; Ophthalmology; Simplexvirus; Thymidine | 1964 |
5-BROMODEOXYURIDINE: EFFECT ON MYOGENESIS IN VITRO.
Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Chick Embryo; Deoxyuridine; DNA; In Vitro Techniques; Metabolism; Muscle Development; Muscles; Myosins; Nucleosides; Pharmacology; Research; Thymidine; Tritium | 1964 |
HERPES SIMPLEX SKIN INFECTION IN RABBITS. I. EFFECT OF 5-IODO-2'-DEOXYURIDINE.
Topics: Antiviral Agents; Deoxyuridine; Herpes Simplex; Hyaluronoglucosaminidase; Idoxuridine; Pharmacology; Rabbits; Research; Thymidine | 1964 |
QUANTITATIVE E.S.R.-MEASUREMENTS OF RADIATION-INDUCED RADICALS IN NUCLEOSIDES.
Topics: Chemistry Techniques, Analytical; Cobalt Isotopes; Deoxyuridine; Electron Spin Resonance Spectroscopy; Idoxuridine; Inorganic Chemicals; Nucleosides; Radiation; Radiation Effects; Research; Thymidine; Uracil Nucleotides | 1964 |
INHIBITION OF URIDINE RIBONUCLEOTIDE SYNTHESIS BY 5-HALOGENATED-2'-DEOXYURIDINE ANALOGUES.
Topics: Antiviral Agents; Brain; Deoxyuridine; Enzyme Inhibitors; Halogenation; Keratitis; Keratitis, Dendritic; Nucleosides; Nucleotides; Organic Chemicals; Orotic Acid; Pharmacology; Rats; Research; Ribonucleotides; Thymidine; Uridine | 1964 |
THE EFFECT OF 5-FLUORO-2'-DEOXYURIDINE ON SYNCHRONOUS MITOSIS IN PHYSARUM POLYCEPHALUM.
Topics: Cell Division; Deoxyuridine; DNA; Floxuridine; Metabolism; Mitosis; Pharmacology; Physarum polycephalum; Plasmodium; Research; RNA; Thymidine; Uridine | 1964 |
ENHANCEMENT BY THYMIDINE ANALOGS OF SUSCEPTIBILITY OF CELLS TO TRANSFORMATION BY SV40.
Topics: Deoxyuridine; Disease Susceptibility; Mice; Nucleosides; Oncogenic Viruses; Pharmacology; Research; Simian virus 40; Thymidine | 1964 |
TEMPERATURE-SENSITIVE MUTANTS OF COLIPHAGE LAMBDA.
Topics: Bacteriophage lambda; Bromodeoxyuridine; Coliphages; Deoxyuridine; Genetics; Hydroxylamines; Mutagens; Mutation; Research; Temperature; Thymidine | 1964 |
TERATOGENIC EFFECTS OF 5-CHLORODEOXYURIDINE ON THE RAT FETUS; PROTECTION BY PHYSIOLOGICAL PYRIMIDINES.
Topics: Abnormalities, Drug-Induced; Deoxyuridine; Fetus; Pharmacology; Pregnancy; Pregnancy, Animal; Pyrimidines; Rats; Research; Thymidine; Toxicology; Uracil Nucleotides | 1964 |
THE COMPARATIVE UPTAKE OF I-125-LABELED 5-IODO-2'-DEOXYURIDINE AND THYMIDINE-H3 INTO TISSUES OF MICE BEARING HEPATOMA-129.
Topics: Carbon Isotopes; Carcinoma, Hepatocellular; Deoxyuridine; DNA; Histocytochemistry; Idoxuridine; Intestine, Small; Intestines; Iodine Isotopes; Liver; Liver Neoplasms; Metabolism; Mice; Neoplasms; Neoplasms, Experimental; Nucleosides; Proteins; Research; Spleen; Thymidine; Trichloroacetic Acid; Tritium | 1965 |
THE INCORPORATION AND DEGRADATION OF PYRIMIDINE DNA PRECURSORS BY HUMAN LEUCOCYTES.
Topics: Autoradiography; Carbon Isotopes; Cytosine Nucleotides; Deoxyuridine; DNA; Humans; Infectious Mononucleosis; Leukemia; Leukemia, Myeloid; Leukocytes; Metabolism; Pyrimidines; Thymidine; Thymine; Tritium; Uracil | 1964 |
PROPERTIES OF DEOXYTHYMIDINE KINASE PARTIALLY PURIFIED FROM NONINFECTED MOUSE FIBROBLAST CELLS.
Topics: Animals; Bromodeoxyuridine; Cell Division; Deoxyuridine; Enzyme Inhibitors; Fibroblasts; Floxuridine; Immune Sera; Kinetics; Mice; Nucleotides; Phosphotransferases; Rabbits; Research; Simplexvirus; Thymidine; Thymidine Kinase; Tritium; Uridine; Vaccinia virus | 1965 |
INHIBITION OF THYMIDINE KINASE FORMATION IN LM (TK-) CELLS SIMULTANEOUSLY INFECTED WITH VACCINIA AND A THYMIDINE KINASELESS VACCINIA MUTANT.
Topics: Deoxyuridine; Enzyme Inhibitors; Fibroblasts; Herpesviridae; Metabolism; Mutation; Research; RNA; RNA, Messenger; Simplexvirus; Thymidine; Thymidine Kinase; Tritium; Vaccinia; Vaccinia virus; Virus Cultivation | 1965 |
ND5 is a hot-spot for multiple atypical mitochondrial DNA deletions in mitochondrial neurogastrointestinal encephalomyopathy.
Topics: Base Sequence; Blotting, Southern; Deoxyuridine; DNA, Mitochondrial; Electron Transport Complex I; Humans; Mitochondrial Encephalomyopathies; Mitochondrial Proteins; Models, Genetic; Molecular Sequence Data; Muscle, Skeletal; Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Deletion; Thymidine; Thymidine Phosphorylase | 2004 |
Molecular characterization of thymidine kinase from Ureaplasma urealyticum: nucleoside analogues as potent inhibitors of mycoplasma growth.
Topics: Amino Acid Sequence; Cell Division; Cloning, Molecular; Deoxyuridine; Escherichia coli; Feedback, Physiological; Molecular Sequence Data; Molecular Weight; Mycoplasma pneumoniae; Nucleosides; Phosphates; Pyrimidine Nucleosides; Recombinant Proteins; Sequence Homology, Amino Acid; Stavudine; Substrate Specificity; Tetrahydrouridine; Thymidine; Thymidine Kinase; Thymine Nucleotides; Ureaplasma urealyticum; Zidovudine | 2003 |
Definitive diagnosis of mitochondrial neurogastrointestinal encephalomyopathy by biochemical assays.
Topics: Chromatography, High Pressure Liquid; Deoxyuridine; Gastrointestinal Diseases; Humans; Mitochondrial Encephalomyopathies; Mutation; Thymidine; Thymidine Phosphorylase | 2004 |
Proximal airway mucous cells of ovalbumin-sensitized and -challenged Brown Norway rats accumulate the neuropeptide calcitonin gene-related peptide.
Topics: Allergens; Animals; Asthma; Bronchoconstrictor Agents; Calcitonin Gene-Related Peptide; Cell Division; Deoxyuridine; Eosinophils; Male; Methacholine Chloride; Microscopy, Confocal; Mucins; Ovalbumin; Rats; Rats, Inbred BN; Respiratory Mucosa; Thymidine | 2004 |
Effect of fluoropyrimidines on the growth of Ureaplasma urealyticum.
Topics: Antimetabolites, Antineoplastic; Cell Proliferation; Deoxyuridine; DNA; Dose-Response Relationship, Drug; Floxuridine; Pyrimidines; Thymidine; Time Factors; Ureaplasma; Ureaplasma urealyticum | 2004 |
Mitochondrial deoxynucleotide pools in quiescent fibroblasts: a possible model for mitochondrial neurogastrointestinal encephalomyopathy (MNGIE).
Topics: Cell Line; Cell Proliferation; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Culture Media; Cytosol; Deoxyribonucleotides; Deoxyuridine; DNA, Mitochondrial; Fibroblasts; Humans; Mitochondria; Mitochondrial Encephalomyopathies; Phosphorylation; Thymidine; Thymidine Kinase; Thymidine Phosphorylase; Time Factors | 2005 |
Thymidine phosphorylase mutations cause instability of mitochondrial DNA.
Topics: Deoxyuridine; DNA, Mitochondrial; Humans; Kidney; Mitochondrial Encephalomyopathies; Models, Biological; Mutation; Thymidine; Thymidine Phosphorylase | 2005 |
Pyrimidine nucleoside salvage confers an advantage to Xenorhabdus nematophila in its host interactions.
Topics: Animals; Deoxyuridine; Manduca; Pyrimidine Nucleosides; Rhabditida; Symbiosis; Thymidine; Thymidine Kinase; Virulence; Xenorhabdus | 2005 |
The value of the deoxyuridine suppression test in megaloblastic anaemia.
Topics: Anemia, Megaloblastic; Antimetabolites; Deoxyuridine; Folic Acid Deficiency; Humans; Predictive Value of Tests; Thymidine; Vitamin B 12 Deficiency | 1978 |
Yersiniophage phiR1-37 is a tailed bacteriophage having a 270 kb DNA genome with thymidine replaced by deoxyuridine.
Topics: Deoxyuridine; DNA, Bacterial; Genome, Viral; Lipopolysaccharides; Molecular Sequence Data; Myoviridae; Thymidine; Yersinia enterocolitica | 2005 |
DNA intramolecular triplexes containing dT --> dU substitutions: unfolding energetics and ligand binding.
Topics: Binding Sites; Calorimetry, Differential Scanning; Circular Dichroism; Deoxyuridine; DNA; Ligands; Netropsin; Nucleic Acid Conformation; Nucleic Acid Denaturation; Structure-Activity Relationship; Temperature; Thermodynamics; Thymidine | 2006 |
Thymidine phosphorylase from Escherichia coli: tight-binding inhibitors as enzyme active-site titrants.
Topics: Binding Sites; Deoxyuridine; Enzyme Inhibitors; Escherichia coli; Models, Molecular; Protein Binding; Recombinant Proteins; Substrate Specificity; Thymidine; Thymidine Phosphorylase | 2006 |
Altered deoxyuridine and thymidine in plasma following capecitabine treatment in colorectal cancer patients.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Deoxyuridine; Female; Fluorouracil; Humans; Male; Thymidine | 2007 |
Infusion of platelets transiently reduces nucleoside overload in MNGIE.
Topics: Adolescent; Adult; Deoxyuridine; Female; Gastrointestinal Diseases; Humans; Male; Mitochondrial Encephalomyopathies; Nervous System Diseases; Platelet Transfusion; Thymidine; Thymidine Phosphorylase | 2006 |
Nucleotide insertion opposite a cyclobutane pyrimidine dimer analogue caused from photoligation by a replicative DNA polymerase.
Topics: Adenine; Deoxyuridine; DNA; Electrophoresis, Microchip; Oligodeoxyribonucleotides; Photochemistry; Polymerase Chain Reaction; Pyrimidine Dimers; Taq Polymerase; Templates, Genetic; Thymidine | 2006 |
Treatment of mitochondrial neurogastrointestinal encephalomyopathy with dialysis.
Topics: Adolescent; Deoxyuridine; Female; Gastrointestinal Diseases; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Mitochondrial Encephalomyopathies; Peritoneal Dialysis; Thymidine | 2007 |
Sensitivity of monkey B virus (Cercopithecine herpesvirus 1) to antiviral drugs: role of thymidine kinase in antiviral activities of substrate analogs and acyclonucleosides.
Topics: Acyclovir; Amino Acid Sequence; Animals; Antiviral Agents; Chlorocebus aethiops; Deoxyuridine; Enzyme Inhibitors; Guanine; Herpesvirus 1, Cercopithecine; Microbial Sensitivity Tests; Molecular Sequence Data; Nucleosides; Phosphorylation; Substrate Specificity; Thymidine; Thymidine Kinase; Vero Cells | 2007 |
Thymidine and deoxyuridine accumulate in tissues of patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE).
Topics: Adolescent; Adult; Autopsy; Biopsy; Deoxyuridine; Female; Gastrointestinal Diseases; Humans; Infant; Male; Mitochondrial Encephalomyopathies; Oxygen; Thymidine; Thymidine Phosphorylase | 2007 |
Antiviral activities and phosphorylation of 5-halo-2'-deoxyuridines and N-methanocarbathymidine in cells infected with vaccinia virus.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cell Line, Tumor; Chlorocebus aethiops; Deoxyuridine; Floxuridine; Humans; Idoxuridine; Mice; Phosphorylation; Thymidine; Thymidine Kinase; Vaccinia; Vaccinia virus; Vero Cells; Viral Plaque Assay | 2008 |
Carrier erythrocyte entrapped thymidine phosphorylase therapy for MNGIE.
Topics: Adult; Deoxyuridine; Drug Delivery Systems; Erythrocyte Transfusion; Erythrocytes; Fatal Outcome; Female; Gastrointestinal Diseases; Genetic Predisposition to Disease; Humans; Liver Diseases; Mitochondrial Diseases; Mutation; Peripheral Nervous System Diseases; Pneumonia; Syndrome; Thymidine; Thymidine Phosphorylase; Treatment Failure | 2008 |
Synthesis of 5-formyl-2'-deoxyuridine and its incorporation into oligodeoxynucleotides.
Topics: Biotechnology; Clinical Laboratory Techniques; Deoxyuridine; Oligodeoxyribonucleotides; Organophosphorus Compounds; Oxidation-Reduction; Thymidine | 2008 |
Facile synthesis and anti-tumor cell activity of Se-containing nucleosides.
Topics: Cell Line, Tumor; Cells, Cultured; Deoxyuridine; Drug Screening Assays, Antitumor; Humans; Male; Prostatic Neoplasms; Selenomethionine; Thymidine | 2009 |
A rapid non-radioactive technique for measurement of repair synthesis in primary human fibroblasts by incorporation of ethynyl deoxyuridine (EdU).
Topics: Cells, Cultured; Deoxyuridine; DNA; DNA Repair; Fibroblasts; Fluorescent Antibody Technique; Humans; Microscopy, Fluorescence; Thymidine; Tritium; Ultraviolet Rays; Xeroderma Pigmentosum | 2009 |
Radiation metabolomics. 2. Dose- and time-dependent urinary excretion of deaminated purines and pyrimidines after sublethal gamma-radiation exposure in mice.
Topics: Analysis of Variance; Animals; Biomarkers; Deamination; Deoxyribonucleosides; Deoxyuridine; Dose-Response Relationship, Radiation; Gamma Rays; Male; Mice; Mice, Inbred C57BL; Multivariate Analysis; Purines; Pyrimidines; Ribonucleosides; Tandem Mass Spectrometry; Thymidine; Time Factors; Xanthine; Xanthines | 2009 |
EdU incorporation is an alternative non-radioactive assay to [(3)H]thymidine uptake for in vitro measurement of mice T-cell proliferations.
Topics: Animals; Antibodies; CD3 Complex; Cell Proliferation; Copper; Deoxyuridine; Flow Cytometry; Mice; Mice, Knockout; Purine-Nucleoside Phosphorylase; Spleen; T-Lymphocytes; Thymidine; Tritium | 2009 |
Chelation-controlled regioselective alkylation of pyrimidine 2'-deoxynucleosides.
Topics: Alkylation; Chelating Agents; Crown Ethers; Deoxycytidine; Deoxyuridine; Electric Impedance; Pyrimidine Nucleosides; Solvents; Stereoisomerism; Substrate Specificity; Thymidine | 2010 |
Correlations of creatine and six related pyrimidine metabolites and diabetic nephropathy in Chinese type 2 diabetic patients.
Topics: Aged; Chromatography, High Pressure Liquid; Creatine; Cytidine; Cytosine; Deoxyuridine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Male; Middle Aged; Pyrimidines; Tandem Mass Spectrometry; Thymidine; Thymine; Uridine | 2010 |
Selective detection of 5-formyl-2'-deoxyuridine, an oxidative lesion of thymidine, in DNA by a fluorogenic reagent.
Topics: Deoxyuridine; DNA; Fluorescent Dyes; Oligodeoxyribonucleotides; Phenols; Spectrometry, Fluorescence; Sulfhydryl Compounds; Thymidine | 2010 |
Immunofluorescent detection of two thymidine analogues (CldU and IdU) in primary tissue.
Topics: Animals; Deoxyuridine; Female; Idoxuridine; Image Processing, Computer-Assisted; Mice; Microscopy, Fluorescence; Pancreas; Thymidine | 2010 |
Quantification of oxidative DNA lesions in tissues of Long-Evans Cinnamon rats by capillary high-performance liquid chromatography-tandem mass spectrometry coupled with stable isotope-dilution method.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Deoxyadenosines; Deoxyguanosine; Deoxyuridine; DNA Damage; DNA Repair; Gene Expression Regulation; Isotopes; Liver; Oxidation-Reduction; Rats; Rats, Inbred LEC; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Stereoisomerism; Tandem Mass Spectrometry; Thymidine; Time Factors | 2011 |
5-Ethynyl-2'-deoxycytidine as a new agent for DNA labeling: detection of proliferating cells.
Topics: Animals; Cell Death; Cell Line, Tumor; Cell Proliferation; Deoxyuridine; DNA; Flow Cytometry; Humans; Mice; Organ Specificity; Staining and Labeling; Thymidine; Time Factors | 2011 |
Auger electron emitter against multiple myeloma--targeted endo-radio-therapy with 125I-labeled thymidine analogue 5-iodo-4'-thio-2'-deoxyuridine.
Topics: Apoptosis; Biological Transport; Caspase 3; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxyuridine; DNA; DNA Fragmentation; Drug Resistance, Neoplasm; Electrons; Humans; Insulin-Like Growth Factor I; Interleukin-6; Molecular Targeted Therapy; Multiple Myeloma; Neoplasm Staging; Thymidine | 2011 |
The giant danio (D. aequipinnatus) as a model of cardiac remodeling and regeneration.
Topics: Animals; Cell Proliferation; Deoxyuridine; Disease Models, Animal; Granulation Tissue; Inflammation; Myocytes, Cardiac; Necrosis; Neovascularization, Pathologic; Pericardium; Regeneration; Thymidine; Ventricular Remodeling; Wound Healing; Zebrafish | 2012 |
Assessment of thymidine phosphorylase function: measurement of plasma thymidine (and deoxyuridine) and thymidine phosphorylase activity.
Topics: Analytic Sample Preparation Methods; Deoxyuridine; Enzyme Assays; Humans; Intestinal Pseudo-Obstruction; Mitochondrial Encephalomyopathies; Muscular Dystrophy, Oculopharyngeal; Ophthalmoplegia; Thymidine; Thymidine Phosphorylase | 2012 |
Cell fate control gene therapy based on engineered variants of human deoxycytidine kinase.
Topics: Animals; Bromodeoxyuridine; Catalytic Domain; Cell Line, Tumor; Deoxycytidine Kinase; Deoxyuridine; Enzyme Activation; Genetic Engineering; Genetic Therapy; Genetic Vectors; Humans; Lentivirus; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasms; Primary Cell Culture; Prodrugs; T-Lymphocytes; Thymidine; Transduction, Genetic; Xenograft Model Antitumor Assays | 2012 |
Metabolism of deoxypyrimidines and deoxypyrimidine antiviral analogs in isolated brain mitochondria.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Deoxycytidine; Deoxyuridine; Dose-Response Relationship, Drug; Kinetics; Male; Mitochondria; Nucleotidases; Phosphorylation; Pyrimidine Nucleosides; Rats; Rats, Sprague-Dawley; Stavudine; Thymidine; Time Factors; Tritium; Zidovudine | 2012 |
Multicolor flow cytometry analysis of the proliferations of T-lymphocyte subsets in vitro by EdU incorporation.
Topics: Animals; Biological Transport; Bromodeoxyuridine; Cell Proliferation; Cells, Cultured; Click Chemistry; Deoxyuridine; Fixatives; Flow Cytometry; Lymphocyte Count; Mice; Mice, Inbred C57BL; Spleen; Staining and Labeling; T-Lymphocyte Subsets; Thymidine | 2012 |
Hypoxia-selective DNA interstrand cross-link formation by two modified nucleosides.
Topics: Base Pairing; Cross-Linking Reagents; Deoxyuridine; DNA; Hypoxia; Molecular Structure; Nucleosides; Photolysis; Thymidine | 2012 |
HPLC-UV analysis of thymidine and deoxyuridine in plasma of patients with thymidine phosphorylase deficiency.
Topics: Adult; Chromatography, High Pressure Liquid; Deoxyuridine; Female; Humans; Intestinal Pseudo-Obstruction; Linear Models; Male; Mitochondrial Encephalomyopathies; Muscular Dystrophy, Oculopharyngeal; Ophthalmoplegia; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Thymidine | 2014 |
Cell-cycle analyses using thymidine analogues in fission yeast.
Topics: Bromodeoxyuridine; Cell Cycle; Cell Proliferation; Deoxyuridine; DNA Replication; DNA, Fungal; Schizosaccharomyces; Staining and Labeling; Thymidine | 2014 |
Thymidine decomposition induced by low-energy electrons and soft X rays under N2 and O2 atmospheres.
Topics: Atmospheric Pressure; Carbon; Deoxyuridine; DNA Damage; Electrons; Glass; Photons; Tandem Mass Spectrometry; Tantalum; Thymidine; X-Rays | 2014 |
Enzymatic synthesis of 2'-deoxyuridine by whole cell catalyst co-expressing uridine phosphorylase and thymidine phosphorylase through auto-induction system.
Topics: Biocatalysis; Deoxyuridine; Enzyme Induction; Escherichia coli; Plasmids; Thymidine; Thymidine Phosphorylase; Uridine Phosphorylase | 2014 |
Mycoplasma pneumoniae thymidine phosphorylase.
Topics: Antineoplastic Agents; Antiviral Agents; Deoxyuridine; Mutation; Mycoplasma pneumoniae; Thymidine; Thymidine Phosphorylase | 2014 |
Flow cytometric evaluation of lymphocyte transformation test based on 5-ethynyl-2'deoxyuridine incorporation as a clinical alternative to tritiated thymidine uptake measurement.
Topics: Antibodies, Monoclonal; Biological Transport; Case-Control Studies; Cell Proliferation; Deoxyuridine; Flow Cytometry; Fluorescent Dyes; Humans; Lymphocyte Activation; Lymphocytes; Phycocyanin; Phytohemagglutinins; Primary Cell Culture; Reproducibility of Results; Shock, Septic; Thymidine; Tritium | 2014 |
A fatal combination: a thymidylate synthase inhibitor with DNA damaging activity.
Topics: Cell Line; Cell Proliferation; Cytotoxins; Deoxyuridine; DNA; DNA Damage; DNA Replication; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Intracellular Space; S Phase; Tetrahydrofolates; Thymidine; Thymidine Monophosphate; Thymidylate Synthase | 2015 |
Reactivity of damaged pyrimidines: formation of a Schiff base intermediate at the glycosidic bond of saturated dihydrouridine.
Topics: Catalysis; Deoxycytidine; Deoxyribose; Deoxyuridine; DNA Glycosylases; Glycosylation; Hydrogen-Ion Concentration; Hydrogenation; Isomerism; Magnetic Resonance Spectroscopy; Palladium; Pyrimidines; Schiff Bases; Tandem Mass Spectrometry; Thymidine | 2015 |
Maternal dietary uridine causes, and deoxyuridine prevents, neural tube closure defects in a mouse model of folate-responsive neural tube defects.
Topics: Animals; Deoxyuridine; Disease Models, Animal; Female; Folic Acid; Folic Acid Deficiency; Glycine Hydroxymethyltransferase; HeLa Cells; Humans; Maternal Nutritional Physiological Phenomena; Mice; Neural Tube; Neural Tube Defects; Pregnancy; Thymidine; Uracil; Uridine | 2015 |
Liver transplant reverses biochemical imbalance in mitochondrial neurogastrointestinal encephalomyopathy.
Topics: Deoxyuridine; Female; Humans; Intestinal Pseudo-Obstruction; Liver Transplantation; Male; Metabolism; Mitochondrial Encephalomyopathies; Muscular Dystrophy, Oculopharyngeal; Ophthalmoplegia; Thymidine; Thymidine Phosphorylase; Treatment Outcome; Young Adult | 2017 |
Hemodialysis in MNGIE transiently reduces serum and urine levels of thymidine and deoxyuridine, but not CSF levels and neurological function.
Topics: Adult; Central Nervous System Diseases; Deoxyuridine; Humans; Intestinal Pseudo-Obstruction; Male; Mitochondrial Encephalomyopathies; Muscular Dystrophy, Oculopharyngeal; Mutation; Ophthalmoplegia; Rare Diseases; Renal Dialysis; Thymidine; Thymidine Phosphorylase | 2017 |
Long-Term Sustained Effect of Liver-Targeted Adeno-Associated Virus Gene Therapy for Mitochondrial Neurogastrointestinal Encephalomyopathy.
Topics: Animals; Carcinogenesis; Deoxyuridine; Dependovirus; Female; Gene Dosage; Genetic Therapy; Genetic Vectors; Intestinal Pseudo-Obstruction; Kaplan-Meier Estimate; Liver; Male; Mice; Mitochondria, Liver; Muscular Dystrophy, Oculopharyngeal; Ophthalmoplegia; Thymidine; Thymidine Phosphorylase; Time Factors; Transgenes | 2018 |
Apolipoprotein A-I Stimulates Cell Proliferation in Bone Marrow Cell Culture.
Topics: Animals; Apolipoprotein A-I; Bone Marrow Cells; Cell Proliferation; Culture Media, Serum-Free; Deoxyuridine; DNA; Dose-Response Relationship, Drug; Granulocytes; Humans; Lipoproteins, HDL; Mesenchymal Stem Cells; Monocytes; Primary Cell Culture; Rats; Rats, Wistar; Thymidine; Tritium | 2018 |
Traceless Tandem Lesion Formation in DNA from a Nitrogen-Centered Purine Radical.
Topics: Base Sequence; Deoxyadenosines; Deoxyuridine; DNA; DNA Damage; Free Radicals; Guanosine; Peroxides; Purines; Thymidine | 2018 |
Administration of a Nucleoside Analog Promotes Cancer Cell Death in a Telomerase-Dependent Manner.
Topics: Aminopeptidases; Cell Death; Cell Line, Tumor; Deoxyuridine; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; DNA; DNA Damage; Gene Silencing; HEK293 Cells; Humans; Models, Biological; Neoplasms; Nuclear Proteins; Nucleosides; Protein Binding; Pyrimidines; RNA, Small Interfering; Serine Proteases; Shelterin Complex; Telomerase; Telomere; Telomere-Binding Proteins; Thymidine; Tripeptidyl-Peptidase 1 | 2018 |
Discovery profiling and bioinformatics analysis of serum microRNA in Mitochondrial NeuroGastroIntestinal Encephalomyopathy (MNGIE).
Topics: Computational Biology; Deoxyuridine; Gene Expression Regulation; Humans; MicroRNAs; Mitochondria; Mitochondrial Encephalomyopathies; Mutation; Nucleotidases; Signal Transduction; Thymidine; Thymidine Phosphorylase | 2018 |
Synthesis and biological assay of new 2'-deoxyuridine dimers containing a 1,2,3-triazole linker. Part I.
Topics: Alkynes; Antineoplastic Agents; Azides; Biological Assay; Cell Line, Tumor; Cell Survival; Click Chemistry; Cycloaddition Reaction; Deoxyuridine; Dimerization; Drug Discovery; Humans; Nucleosides; Thymidine; Triazoles | 2019 |
Mitochondrial neurogastrointestinal encephalopathy: a clinicopathological mimic of Crohn's disease.
Topics: Adult; Age of Onset; Azathioprine; Crohn Disease; Deoxyuridine; Diagnosis, Differential; Female; Gastrointestinal Diseases; Humans; Mitochondrial Encephalomyopathies; Phenotype; Point Mutation; Retrospective Studies; Thymidine; Thymidine Phosphorylase; White Matter | 2019 |
Control of Energy Transfer Between Pyrene- and Perylene-Nucleosides by the Sequence of DNA-Templated Supramolecular Assemblies.
Topics: Base Sequence; Deoxyuridine; DNA, Single-Stranded; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Nucleic Acid Conformation; Nucleosides; Perylene; Pyrenes; Spectrometry, Fluorescence; Thymidine | 2020 |
Structural and catalytic analysis of two diverse uridine phosphorylases in Phytophthora capsici.
Topics: Binding Sites; Catalysis; Catalytic Domain; Crystallography, X-Ray; Deoxyuridine; Ligands; Phytophthora; Pyrimidines; Ribosemonophosphates; Thymidine; Uracil; Uridine; Uridine Phosphorylase | 2020 |
Determination of substituent effects on the proton affinities of natural nucleosides by the kinetic method.
Topics: Deoxyuridine; DNA; Kinetics; Nucleosides; Protons; RNA; Spectrometry, Mass, Electrospray Ionization; Thymidine | 2021 |
A new family of globally distributed lytic roseophages with unusual deoxythymidine to deoxyuridine substitution.
Topics: Bacteriophages; Deoxyuridine; DNA, Viral; Ecosystem; Genome, Viral; Phylogeny; Roseobacter; Thymidine | 2021 |
The bioavailability time of commonly used thymidine analogues after intraperitoneal delivery in mice: labeling kinetics in vivo and clearance from blood serum.
Topics: Animals; Biological Availability; Bromodeoxyuridine; Dentate Gyrus; Deoxyuridine; Glyburide; Injections, Intraperitoneal; Kinetics; Mice; Mice, Inbred C57BL; Thymidine | 2022 |
The nucleotide metabolome of germinating Arabidopsis thaliana seeds reveals a central role for thymidine phosphorylation in chloroplast development.
Topics: Arabidopsis; Arabidopsis Proteins; Chloroplasts; Deoxyribonucleotides; Deoxyuridine; DNA, Chloroplast; Germination; Metabolome; Nucleotides; Phosphorylation; Pyrophosphatases; Seedlings; Seeds; Thymidine; Thymidine Kinase | 2022 |
Nucleotide excision repair removes thymidine analog 5-ethynyl-2'-deoxyuridine from the mammalian genome.
Topics: Deoxyuridine; DNA; DNA Damage; DNA Repair; Genome, Human; Humans; Thymidine; Transcription, Genetic; Ultraviolet Rays | 2022 |