thymidine has been researched along with deoxycytidine in 393 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 254 (64.63) | 18.7374 |
| 1990's | 55 (13.99) | 18.2507 |
| 2000's | 45 (11.45) | 29.6817 |
| 2010's | 34 (8.65) | 24.3611 |
| 2020's | 5 (1.27) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, MS; Prusoff, WH; Schinazi, RF | 1 |
| Horwitz, JP; Kessel, D; Meltsner, BR; Palomino, E | 1 |
| Bobek, M; Cheng, YC; Dutschman, G; Grill, S; Kavai, I; Sharma, RA | 1 |
| Baba, M; Balzarini, J; Broder, S; De Clercq, E; Herdewijn, P; Pauwels, R; Vanderhaeghe, H | 1 |
| Bloomer, LC; Patil, VD; Townsend, LB; Wise, DS; Wotring, LL | 1 |
| Chawla, RR; Freed, JJ; Hampton, A | 1 |
| Björck, L; Clausen, AR; Piskur, J; Sandrini, MP; Shannon, O | 1 |
| Harano, A; Hatano, A; Nakagomi, Y; Naramoto, Y; Takigawa, Y; Toda, K; Yamada, H | 1 |
| Li, Y; Liotta, DC; Liu, L; Lutz, S; Soni, PB; Zhang, X | 1 |
| Schreiber, C; Waxman, S | 1 |
| Hackstadt, T; Mallavia, LP | 1 |
| Boldogh, I; Roubal, J; Vejsada, J; Vonka, V; Závada, V | 1 |
| Clements, GB | 1 |
| Abbasi, MM; Beisler, JA; Voytek, P; Wolpert-DeFilippes, MK | 1 |
| Cihák, A; Veselý, J | 3 |
| Balboni, PG; Barbanti-Brodano, G; de Vries, J; Fiume, L; Mattioli, A; Tognon, M; Wieland, T | 1 |
| Dachselt, U; Helpap, B | 1 |
| Bigar, F | 1 |
| Abbott, MT; Hsu, CA; Shaffer, PM | 1 |
| Chu, BC; Lawley, PD | 2 |
| Feinendegan, LE; Myers, DK | 1 |
| Roberts, D; Warmath, EV | 1 |
| Forsdyke, DR; Scott, FW | 2 |
| Baker, PN; Bradshaw, TK; Burke, DC; Morser, J | 1 |
| Capozza, FE; Kelman, AD; Kibrick, S | 1 |
| Norin, AJ; Strauss, BS | 1 |
| Hilliard, JK; Sneider, TW | 1 |
| Feltkamp-Vroom, TM; Helder, AW; Lucas, CJ; Splinter, TA | 1 |
| Jamieson, AT; Subak-Shape, JH | 1 |
| Hoshi, A; Riesz, P; Rustgi, S | 1 |
| Marz, R; Plagemann, PG; Wohlhueter, RM | 1 |
| Chen, MS; Prusoff, WH | 1 |
| Polmar, SH | 1 |
| Burton, WG; Grabowy, CT; Sager, R | 1 |
| Hofert, JF; Novak, RA | 1 |
| Bengtson, A; Billardon, C; Diatloff, C; Macieira-Coelho, A | 1 |
| Akasaka, TL; Miller, JJ; Olds-Arroyo, L | 1 |
| Miyamoto, H; Osogoe, B | 2 |
| van Rooijen, N | 1 |
| Abbott, PJ; Saffhill, R | 1 |
| Miller, JJ; Olds-Arroyo, L | 1 |
| Chawla, RR; Hampton, A; Kappler, F | 1 |
| Peterson, AR; Peterson, H | 1 |
| Pabst, R; Trepel, F | 1 |
| Mattoccia, LP; Sorrentino, R | 1 |
| Gunderina, LI | 1 |
| Bradley, MO; Sharkey, NA | 1 |
| Bobo, B; Drewinko, B | 1 |
| Lozovskaya, ER; Prokofieva-Belgovskaya, AA; Slesinger, SI | 1 |
| Brooks, RF | 1 |
| Davidson, RL; Kaufman, ER | 2 |
| Baĭramian, TL; Zakharov, AF | 2 |
| Heidelberger, C; Landolph, JR; Peterson, AR; Peterson, H | 1 |
| Evans, HH; Evans, TE; Littman, SR | 1 |
| Chiu, CS; Greenberg, GR; Tomich, PK; Wovcha, MG | 1 |
| Birnboim, HC | 1 |
| Barry, DW; Grimley, PM; Hulanicka, B | 1 |
| Spindle, AI | 1 |
| Erbe, J; Marz, R; Plagemann, PG | 1 |
| Bechynĕ, M; Buric, L; Dientsbier, Z; Foltýnová, V; Kovaríková, H; Mostecký, H | 1 |
| Hirt, A; Wagner, HP | 1 |
| Minowada, J; Sandberg, AA; Shiraishi, Y; Weinfeld, H | 1 |
| Kato, S; Mantani, M | 1 |
| Brun, G; Goodgame, DM; Skapski, AC | 1 |
| Gentry, GA; Hill, JM; Morse, PA | 1 |
| Hofert, HF; Laugen, RH | 1 |
| Buric, L; Dienstbier, Z | 1 |
| Rooijen, NV | 1 |
| Adamson, DJ; Carpenter, JW; Nelson, JA; Rose, LM | 1 |
| Lee, MJ; Roth, SI | 1 |
| Coulter, MB; Ng, SK; Rogers, J; Sanwal, BD | 1 |
| Maier, G; Werner, D | 1 |
| Bäck, R; Linna, TJ | 1 |
| Amano, M; Everett, NB; Tsutsui, I | 1 |
| Clements, GB; Subak-Sharpe, JH | 1 |
| Ratliff, RL; Walters, RA | 1 |
| Ganeshaguru, K; Hoffbrand, AV; Tattersall, MH | 1 |
| Burchenal, JH; Chu, CK; Ciovacco, K; Dowling, MD; Fox, JJ; Kalaher, K; Kiefner, R; O'Toole, T; Watanabe, KA; Wempen, I | 1 |
| Amano, M; Everett, NB | 1 |
| Bachvarova, R; Baran, MM; Pollard, DR | 1 |
| Arnér, ES; Eriksson, S; Spasokoukotskaja, T | 1 |
| Snyder, RD | 1 |
| Bjerknes, R; Haaskjold, E; Refsum, H; Refsum, SB | 1 |
| Davey, RA; Ey, PL; Mayrhofer, G | 1 |
| Ogata, T; Shiraishi, Y; Soma, H | 1 |
| Sasvári-Székely, M; Spasokukotskaja, T; Staub, M; Taljanidisz, J | 2 |
| Montgomery, JA; Riordan, JM; Secrist, JA; Tiwari, KN | 1 |
| De Clercq, E; Marquez, VE; Murase, J | 1 |
| Griffiths, MJ; Strachan, MC | 1 |
| Howell, ML; Mathews, CK; Slabaugh, MB; Wang, Y | 1 |
| Cohen, JD; Robins, HI; Schmitt, CL | 1 |
| Achkar, WA; Dutrillaux, B; Hilali, A; Léonard, A; Léonard, ED; Martins, B; Sabatier, L | 1 |
| August, EM; Marongiu, ME; Prusoff, WH | 1 |
| Berger, M; Cadet, J; Decarroz, C; van Lier, JE; Wagner, JR | 1 |
| Mukai, F; Segal, A; Solomon, JJ | 1 |
| Hiramoto, K; Kimoto, H; Narahara, K | 1 |
| Binnie, C; Coote, JG | 1 |
| De Clercq, E | 2 |
| Lin, TS; Prusoff, WH; Schinazi, RF | 1 |
| Botti, RE; Imperia, PS; Lass, JH; Lazarus, HM; Mack, RJ | 1 |
| Balonov, MI; Chetchueva, ME; Pomerantseva, MD; Ramaĭa, LK; Zhesko, TV | 1 |
| Balzarini, J; De Clercq, E; Herdewijn, P | 1 |
| Cheng, YC; Cohen, JS; Dutschman, GE; Gao, WY; Stein, CA | 1 |
| Shirai, T; Umeda, M | 1 |
| Gildea, B; McLaughlin, LW | 1 |
| Baba, M; Balzarini, J; De Clercq, E; Herdewijn, P; Pauwels, R; Schols, D; Van Aerschot, A | 1 |
| Colacino, JM; Wolcott, RM | 1 |
| Rabes, HM; Röttgen, V | 1 |
| Antoni, F; Horváth, L; Sasvári-Székely, M; Spasokukotskaja, T; Staub, M | 1 |
| Kopper, L; Pogany, G; Sasvári-Székely, M; Soóki-Tóth, A; Spasokukotskaja, T; Staub, M | 1 |
| Shiraishi, Y; Taguchi, T | 1 |
| Lönn, S; Lönn, U; Nylen, U; Winblad, G | 1 |
| Balzarini, J; De Clercq, E; Desmyter, J; Goubau, P; Herdewijn, P; Pauwels, R; Vandeputte, M; Vanderhaeghe, H | 1 |
| Carson, DA; Kornbluth, RS; Richman, DD | 1 |
| Balzarini, J; De Clercq, E | 2 |
| Miller, JL | 1 |
| Balzarini, J; Broder, S; Cooney, DA; Cupp, JE; Dalal, M; DeClercq, E; Johns, DG; Kang, GJ | 1 |
| Baba, M; Balzarini, J; Broder, S; de Clercq, E; Herdewijn, P; Johns, DG; Pauwels, R | 1 |
| Brady, RO; O'Neill, RR | 1 |
| Broder, S; Mitsuya, H | 2 |
| Baba, M; Balzarini, J; De Clerq, E; Herdewijn, P; Pauwels, R | 1 |
| Chou, TC; Coleman, LA; Durno, AG; Hirsch, MS; Kaplan, JC; Paradis, TJ; Schooley, RT; Vogt, MW | 1 |
| Balfour, HH; Henry, K; Thurn, JR | 1 |
| Pardridge, WM; Terasaki, T | 1 |
| Zagris, N | 1 |
| Allain, JP; Dubinsky, R; Fischl, MA; Klecker, RW; McAtee, N; McNeely, MC; Perno, CF; Thomas, RV; Wills, RJ; Yarchoan, R | 1 |
| Chu, EH; Li, IC; Wu, CL | 1 |
| Attanasio, R; Johnson, JC | 1 |
| Benczur, M; Spasokukotskaja, T; Staub, M; Taljanidisz, J | 1 |
| Bubley, G; Crumpacker, C; Oliver, S | 1 |
| Ikeda, S; Ives, DH | 1 |
| Barry, DW; Biron, KK; Ellis, MN; Furman, PA; Keller, PM; Lehrman, SN; Martin, JL | 1 |
| Chen, MS; Kinney-Thomas, E; Lin, TS; Prusoff, WH; Schinazi, RF | 1 |
| Offerhaus, L | 1 |
| Broder, S; Matsushita, S; Mitsuya, H; Reitz, MS | 1 |
| Cleaver, JE; Milam, KM; Thomas, GH | 1 |
| Cadet, J; Gaboriau, F; Moysan, A; Vigny, P; Voituriez, L | 1 |
| Danenberg, PV; Ibric, LL; Peterson, AR; Peterson, H | 1 |
| Benedict, WF; Heidelberger, C; Peterson, AR | 1 |
| Antoni, F; Benczur, M; Spasokukotskaja, T; Staub, M | 1 |
| Chavez, F; Kúsmierek, JT; Loeb, LA; Preston, BD; Sagi, J; Singer, B; Spengler, SJ | 1 |
| Bianchi, V; Pontis, E; Reichard, P | 1 |
| Fondu, P; Lebacq, AM; Mandelbaum, IM; Vertongen, F | 1 |
| Sirotkin, K | 1 |
| Abbondandolo, A; Bonatti, S; Di Leonardo, A; Randazzo, R | 1 |
| Papiernik, M; Penit, C | 1 |
| Roberts, SH; Wheater, RF | 1 |
| Bhalla, K; Grant, S | 1 |
| Bergstrom, D; Kahilainen, L; Kangas, L; Vilpo, JA | 1 |
| Lin, TS; Prusoff, WH | 1 |
| Kornberg, A; Spector, R | 1 |
| Dahbo, Y; Eriksson, S | 1 |
| Ashman, CR; Davidson, RL; Kaufman, ER | 1 |
| Nicander, B; Reichard, P | 3 |
| Antoni, F; Sasvari-Szekely, M; Spasokutotskaja, T; Staub, M; Taljanidisz, J | 1 |
| Ayers, O; Malinowski, N; Moyer, JD | 1 |
| Cohen, A; Leung, C; Thompson, E | 1 |
| Malick, NC; Snyder, RD | 1 |
| Czaker, R; Schnedl, W | 1 |
| Pauli, RM; Strauss, BS | 1 |
| Forsdyke, DR; Sjostrom, DA | 1 |
| Yoshirkura, H | 1 |
| Bertinchamps, AJ; Mathur-De Vré, R | 1 |
| Bevers, MM; van Rijn, J; van Wijk, R; Wicks, WD | 1 |
| Komatsu, Y; Tanaka, K | 1 |
| Sneider, TW | 1 |
| Chan, TS; Green, H; Meuth, M | 1 |
| Goodman, JI | 1 |
| Swetly, P; Watanabe, Y | 1 |
| Cumming, RB; Sega, GA; Walton, MF | 1 |
| Chang, SY; Derge, JG; Hampar, B; Nonoyama, M; Showalter, SD; Tagamets, A | 1 |
| Gentry, GA; Jamieson, AT; Subak-Sharpe, JH | 1 |
| Green, H; Meuth, M | 1 |
| Long, C; Rubio, V | 1 |
| Barkken, A; Bird, A; Rochaix, JD | 1 |
| Bloch, A; McPartland, RP; Wang, MC; Weinfeld, H | 1 |
| Tupitsyna, LP | 1 |
| Everett, NB; Osogoe, B; Tyler, RW | 1 |
| Bailey, P; Bryant, S; Burrs, A; Doctor, VM | 1 |
| Cunningham, DD; Remo, RA | 1 |
| Harrap, KR; Tattersall, MH | 1 |
| Bernardi, G; Ehrlich, SD; Laval, J; Paoletti, C; Thiery, JP | 1 |
| Kochetkov, NK; Kost, AA; Shibaev, VN | 1 |
| Beaudreau, G; Cottler-Fox, M; Heine, U; Weber, GH | 1 |
| Durham, JP; Hay, J; Howard, DK; Melvin, WT | 1 |
| Anderson, S; Bryan, AM; Davis, GC; Olafsson, PG | 1 |
| Hofert, JF | 1 |
| Fuchs, JA; Neuhard, J | 1 |
| Bernardi, G; Devillers-Thiery, A; Ehrlich, SD | 1 |
| Bernardi, G; Bertazzoni, U; Ehrlich, SD | 2 |
| Taketo, A; Taketo, Y | 1 |
| Bjursell, G; Reichard, P | 1 |
| Billen, D; Schneiderman, MH | 1 |
| Loeb, LA; Williams, RO | 1 |
| Schmieder, J; Wigand, R | 1 |
| Schnedl, W | 1 |
| Bello, LJ; May, MS | 1 |
| Dingman, CW; Peacock, AC; Salomon, R; Zeiger, RS | 1 |
| Lozovskaia, ER; Prokof'eva-Bel'govskaia, AA; Slezinger, SI | 1 |
| Kinkade, JM | 1 |
| Jekunen, A; Puukka, M; Vilpo, J | 1 |
| Hudson, JB | 1 |
| Fox, JJ; Lopez, C; Watanabe, KA | 1 |
| Durkacz, BW; Gray, DA; Shall, S | 1 |
| Crea, R; Dinkelspiel, K; Manzini, G; Quadrifoglio, F; Vasser, M | 1 |
| Fox, RM; Kefford, RF; Taylor, IW; Tripp, EH | 1 |
| Cote, IL; Decker, K; Segal, A; Solomon, JJ; Wortman, M | 1 |
| Downes, CS; Johnson, RT; Yew, FF | 1 |
| Dizdaroglu, M | 1 |
| Hatayama, T; Nakamura, T; Yukioka, M | 1 |
| Hayward, IP; Parsons, PG | 1 |
| Carlson, J; Keoffler, HP; Yen, J | 1 |
| Covey, JM; Zaharko, DS | 1 |
| Bover, L; Cabral, S; Leis, S; Mordoh, J; Nembrot, M | 1 |
| Amano, M; Hamatani, K; Kawahara, A | 1 |
| Samuels, LL; Straw, JA | 1 |
| Clarkson, BD; Doblin, JM; Fried, J; Perez, AG | 2 |
| Green, CG; Mettes, HJ; Shearer, WT | 1 |
| Perry, PE | 1 |
| Andreeff, M; Blumenreich, MS; Chou, TC; Clarkson, BD; Vale, K; Young, CW | 1 |
| Morgan, WF; Wolff, S | 1 |
| Balzarini, J; De Clercq, E; Hunston, RN; Jones, AS; McGuigan, C; Walker, RT | 1 |
| Boehm, TL; Drahovsky, D; Kreis, W | 1 |
| Fujiki, Y; Nakashima, K | 1 |
| Cysyk, RL; Hoerauf, RM; Karle, JM | 1 |
| Akman, SA; Andrews, PA; Bachur, NR; Chou, FE; Rosen, H; Ross, DD; Salinger, C | 1 |
| Breatnach, F; Ganeshaguru, K; Hoffbrand, AV; Lee, N; Piga, A; Prentice, HG | 1 |
| Ramonas, LM; Zaharko, DS | 1 |
| Cremer, C; Cremer, T; Simickova, M | 1 |
| Kumar, A; Nakatsugawa, S; Sugahara, T | 1 |
| Fox, RM; Tattersall, MH; Tripp, EH | 1 |
| Cox, EC; Erlich, HA | 1 |
| Lin, SL; Takii, M; Ts'o, PO | 1 |
| Brennand, J; Fox, M; Saffhill, R | 1 |
| Hearst, JE; Kanne, D; Rapoport, H; Straub, K | 1 |
| Braun, TJ; Burchenal, JH; Chou, TC; Fox, JJ; Philips, FS; Schmid, FA; Su, TL; Watanabe, KA | 1 |
| Okada, T; Osogoe, B | 1 |
| Brennand, J; Fox, M; McMillan, S | 1 |
| Scott, WJ | 1 |
| Bisel, TU; Uyeki, EM; Wierzba, K | 1 |
| Dayton, PG; Israili, ZH | 1 |
| Deveski, WB; Dudman, NP; Tattersall, MH | 1 |
| Mastro, AM; Pepin, KG | 1 |
| Danhauser, LL; Rustum, YM | 1 |
| Blehová, Z; Dienstbier, Z; Masopust, J; Sámal, M | 1 |
| Cadman, E; Grant, S; Lehman, C | 1 |
| Amano, M; Hamatani, K | 1 |
| Bairamjan, TL; Zakharov, AF | 1 |
| Bøyum, A; Løvhaug, D; Nordlie, EM; Seeberg, E | 1 |
| Sasvari-Szekely, M; Solymossy, M; Staub, M; Szikla, K | 1 |
| Meerman, JH; Nelson, SD; van Beerendonk, GJ | 1 |
| Cadet, J; Douki, T | 1 |
| Kazimierczuk, Z; Piróth, Z; Sasvári-Székely, M; Staub, M | 1 |
| Hayatsu, H; Nawamura, T; Negishi, K | 1 |
| Bianchi, V; Bonvini, P; Borella, S; Ferraro, P; Reichard, P | 1 |
| Eriksson, S; Hultgren, C; Karlsson, A; Meyerhans, A; Plikat, U; Vartanian, JP; Wain-Hobson, S; Wang, L | 1 |
| Sasvári-Székely, M; Spasokukotskaja, T; Staub, M | 1 |
| Cohen, JD; Javid, MJ; Katz, TB; Kuzminsky, SR; Miller, EM; Robins, HI | 1 |
| Hrabák, A; Spasokukotskaja, T; Staub, M; Temesi, A | 1 |
| Chan, TS; Sato, T | 1 |
| Decker-Samuelian, K; Singh, US; Solomon, JJ | 1 |
| Smith, G | 1 |
| Bernabei, PA; D'Ippolito, G; Ermini, A; Rossi-Ferrini, P; Santini, V; Zoccolante, A | 1 |
| Lawrence, TS; McGinn, CJ; Shewach, DS | 1 |
| Cullinan, D; de los Santos, C; Eisenberg, M; Grollman, AP; Korobka, A; Patel, DJ | 1 |
| Johansson, M; Karlsson, A | 1 |
| Munch-Petersen, B | 2 |
| Berdel, WE; Bergmann, J; Brachwitz, H; Langen, P; Thomas, Y | 1 |
| Eichman, BF; Ho, PS; Mooers, BH | 1 |
| Abul-Hajj, YJ; Akanni, A | 1 |
| Altmann, A; Bellemann, ME; Blatter, J; Brix, G; Doll, J; Gerlach, L; Haberkorn, U; Morr, I; Oberdorfer, F; van Kaick, G | 1 |
| Elstein, KH; Kavlock, RJ; Lau, C; Mole, ML; Rogers, JM; Setzer, RW; Zucker, RM | 1 |
| Focher, F; Priori, G; Spadari, S; Tondelli, L; Verri, A | 1 |
| Costanzo, G; Crestini, C; Di Mauro, E; Mincione, E; Negri, R; Saladino, R | 1 |
| Munch-Petersen, B; Piskur, J; Sondergaard, L | 1 |
| Thomas, GJ; Wen, ZQ | 1 |
| Kainosho, M; Ono, A; Takaishi, N; Tate, S; Tatebe, M | 1 |
| Csapó, Z; Eriksson, S; Sasvári-Székely, M; Spasokoukotskaja, T; Staub, M | 1 |
| Csapó, Z; Keszler, G; Noordhuis, P; Peters, GJ; Sasvári-Székely, M; Smid, K; Staub, M | 1 |
| Fukada, S; Iwamoto-Tanaka, N; Kasai, H | 1 |
| Eriksson, S; Neuhard, J; Wang, J | 1 |
| Busi, C; Derenzini, M; Di Stefano, G; Fiume, L; Mattioli, A; Trerè, D | 1 |
| Drake, RR; Gilbert, KM; Hinds, TA; Wilbert, TN | 1 |
| Cullinan, D; de los Santos, C; Eisenberg, M | 1 |
| Balzarini, J; Breuer, M; De Clercq, E; Degrève, B; Hatse, S; Huybrechts, R; Johansson, M; Karlsson, A | 1 |
| Achanta, G; Feng, L; Huang, P; Pelicano, H; Plunkett, W; Zhang, W | 1 |
| Enger, MD; Gurley, LR; Ratliff, RL; Tobey, RA; Walters, RA | 1 |
| Johansson, M; Karlsson, A; Zheng, X | 1 |
| Eriksson, S; Wang, L | 2 |
| Bridges, EG; Bryant, ML; Cote, P; Cretton-Scott, E; Dukhan, D; Faraj, A; Gosselin, G; Hernandez, B; Imbach, JL; Juodawlkis, A; Korba, B; Loi, AG; Marion, P; Pierra, C; Placidi, L; Schinazi, RF; Sommadossi, JP; Tennant, B | 1 |
| Altmann, A; Bellemann, ME; Blatter, J; Brix, G; Doll, J; Haberkorn, U; Kamencic, H; Kinscherf, R; Morr, I; Traut, U | 1 |
| Guengerich, FP; Hartman, MK; Manier, ML; Marsch, GA; Morris, BJ; Mundkowski, RG | 1 |
| Choi, JY; Chung, MH; Doetsch, PW; Kim, JE; Kim, JS; You, HJ | 1 |
| Jung, CP; Motwani, MV; Schwartz, GK | 1 |
| Evans, VJ; Price, FM; Rotherham, J | 2 |
| Cinatl, J; Doerr, HW; Gosselin, G; Gröschel, B; Imbach, JL; Périgaud, C | 1 |
| Kobori, A; Miyata, K; Seio, K; Sekine, M; Ushioda, M | 1 |
| Bergström, M; Borbath, I; Grégoire, V; Långström, B; Laryea, D; Pauwels, S | 1 |
| Brouwer, J; de Ruijter, M; Lugtenburg, J; Ouwerkerk, N; Raap, J; Steenweg, M; van Boom, JH | 1 |
| Bridges, EG; Bryant, ML; Cretton-Scott, E; Dukhan, D; Faraj, A; Gosselin, G; Hernandez-Santiago, B; Imbach, JL; Pierra, C; Placidi, L; Rodriguez-Orengo, J; Sommadossi, JP | 1 |
| Ashihara, H; Katahira, R | 1 |
| Bartsch, H; Dienemann, H; Drings, P; Godschalk, R; Kayser, K; Nair, J; Risch, A; van Schooten, FJ | 1 |
| Kazimierczuk, Z; Keszler, G; Sasvari-Szekely, M; Spasokoukotskaja, T; Staub, M; Szikla, K | 1 |
| Ben-Yoseph, O; Chenevert, TL; Garwood, M; Kim, B; Rehemtulla, A; Ross, BD; Stegman, LD; Sunkara, PS; Zwolshen, J | 1 |
| Fernandes, A; Freisinger, E; Grollman, AP; Kisker, C | 1 |
| BARNER, HD; COHEN, SS | 1 |
| MALEY, F; MALEY, GF | 2 |
| FISCHER, GA; MORRIS, NR | 1 |
| BENES, L; SOSKA, J | 1 |
| POLLARD, M; SHARON, N | 1 |
| DELAMORE, IW; PRUSOFF, WH | 1 |
| MURRAY, A; PETERSEN, DF | 1 |
| KHORANA, HG; RALPH, RK; SMITH, RA | 1 |
| Buti, M; Esteban, R | 1 |
| Florea-Wang, D; Haapala, E; Hakala, K; Hovinen, J; Mattinen, J; Vilpo, J | 1 |
| Lok, AS | 1 |
| Gu, J; Schaefer, HF; Xie, Y | 1 |
| Farquhar, D; Khan, SR; Nowak, B; Plunkett, W | 1 |
| Backman, J; Ellingsen, DG; Greibrokk, T; Kronberg, L; Lundanes, E; Molander, P; Olsen, R; Sjöholm, R; Thomassen, Y; Thorud, S; Øvrebø, S | 1 |
| Clarke, SJ; Hoskins, J; Li, KM; Rivory, LP; Sharma, R | 1 |
| Fujimoto, S; Hotta, A; Koma, M; Nagai, K; Nagasawa, K | 1 |
| Chappey, C; Gerondelis, P; Lanier, ER; Parkin, N; Ross, LL; St Clair, MH; Underwood, MR | 1 |
| Aoki, K; Ohkubo, A; Seio, K; Sekine, M; Taguchi, H | 1 |
| Gerth, ML; Lutz, S | 1 |
| He, J; Lin, L; Lindsay, S; Zhang, P | 1 |
| Goto, T; Kato, N; Omata, M | 1 |
| Ayoub, WS; Keeffe, EB | 1 |
| Benner, SA; Chen, F; Hoshika, S; Leal, NA | 1 |
| Buti, M | 1 |
| González-Diéguez, ML; Rodríguez, M | 1 |
| Barreiro, P; García-Samaniego, J; Martín-Carbonero, L | 1 |
| Hazra, S; Konrad, M; Lavie, A; Ort, S; Sabini, E | 1 |
| Dong, L; He, XD; Hu, SL; Li, M; Shen, ZJ; Tao, SN; Zhu, YY | 1 |
| Borroto-Esoda, K; Curtis, M; Miller, MD; Qi, X; Zhu, Y | 1 |
| Barreiro, P; Fernández, JV; Labarga, P; Medrano, J; Soriano, V; Tuma, P; Vispo, E | 1 |
| Boccafoglio, F; Concia, E; Gottardi, M; Lanzafame, M; Lattuada, E; Soldani, F | 1 |
| Jain, M; Mittal, B; Singh, H | 1 |
| Champavier, Y; Guilloton, M; Lucas, R; Teste, K; Zerrouki, R | 1 |
| Ball, LM; Chen, X; Collins, LB; Gold, A; Lu, K; Swenberg, JA; Ye, W; Zhou, L | 1 |
| Eriksson, S; Sun, R; Wang, L | 1 |
| Laclair, DD; McKee, EE; Morris, GW | 1 |
| Hazra, S; Konrad, M; Lavie, A; Ort, S | 1 |
| Benhamou, Y; Pais, R | 1 |
| Mallet, V; Pol, S; Vallet-Pichard, A | 1 |
| Suzuki, F | 2 |
| McCann, KA; McKee, EE; Williams, DW | 1 |
| Ali, A; Andreasson, E; Clausen, AR; Girandon, L; Knecht, W; Munch-Petersen, B; Piškur, J; Rozpedowska, E; Sandrini, MP | 1 |
| Amin, J; Cooper, DA; Cordery, DV; Emery, S; Kelleher, AD; Martin, A | 1 |
| Brovarets', OO; Hovorun, DM; Zhurakivsky, RO | 1 |
| Bogdan, D; Morari, C | 1 |
| Brooks, PJ; Fisher, DE; Guerrero, C; Liu, S; Mitra, D; Song, H; Su, Y; Wang, J; Wang, Y; Zeng, Y | 1 |
| Antinori, A; Bansi, L; Boumis, E; Callegaro, A; Ceccherini-Silberstein, F; Dunn, D; Fearnhill, E; Forbici, F; Francisci, D; Maggiolo, F; Mussini, C; Nicastri, E; Palamara, G; Perno, CF; Sabin, C; Santoro, MM; Zazzi, M; Zoncada, A | 1 |
| Abel, G; Barthelmes, J; Dueregger, A; Guggenberger, F; Haunschild, J; Intelmann, D; Klocker, H; Ramoner, R; Sampson, N; Schuh, M; Stecher, G | 1 |
| Aoki, M; Desai, DV; Kodama, EN; Maeda, K; Mitsuya, H; Nakata, H | 1 |
| Dunwell, JM; Dunwell, TL; Liu, S; Pfeifer, GP; Ullah, I; Wang, Y | 1 |
| Balzarini, J; Fieuws, S; Hofer, A; Liekens, S; Noppen, S; Ranjbarian, F; Sabuncuoğlu, S; Vande Voorde, J | 1 |
| Haque, MM; Liu, S; Peng, X; Sun, H; Wang, Y | 1 |
| Locarnini, S; Warner, N | 1 |
| Foksinski, M; Gackowski, D; Guz, J; Olinski, R; Rozalski, R | 1 |
| Sun, R; Wang, L | 1 |
| El Safadi, Y; Isel, C; Laumond, G; Marquet, R; Moog, C; Paillart, JC; Smyth, RP; Vivet-Boudou, V | 1 |
| Chomicz, L; Jian, Y; Li, L; Lin, G | 1 |
| Paschke, H; Reemtsma, T; Schmied-Tobies, MI | 1 |
| Čoga, L; Drevenšek-Olenik, I; Masiero, S; Spindler, L | 1 |
| Ji, D; Li, L; Suo, Z; Wang, J; Wang, P; Wang, Y; Williams, NL; Wu, J; You, C; Zahurancik, WJ | 1 |
| Cui, Y; Wang, P; Wang, Y; Yu, Y; Yuan, J | 1 |
| Hu, Y; Smith, DE; Thompson, BR | 1 |
| Furusawa, M; Kumagai, M; Suzuki, T | 1 |
| Imai, A; Kohzu, A; Komatsu, K; Sano, T; Shimode, S; Shinohara, R; Toda, T; Tomioka, N; Tsuchiya, K | 1 |
| Castaño Mendez, A; Corral Blanco, M; De Fuenmayor Fernandez de la Hoz, C; Dominguez-Gonzalez, C; Hernandez-Voth, A; Martin, MA; Sayas Catalan, J; Villena Garrido, V | 1 |
| Ozawa-Tamura, A; Sasabe, Y; Suzuki, T; Takeuchi, M | 1 |
| Peña-Gómez, MJ; Rosado, IV; Suárez-Pizarro, M | 1 |
| García-Calderón, CB; Klimašauskas, S; Moreno-Gordillo, P; Narmontė, M; Peña-Gómez, MJ; Rosado, IV; Rukšėnaitė, A | 1 |
19 review(s) available for thymidine and deoxycytidine
| Article | Year |
|---|---|
Selection of biochemically variant, in some cases mutant, mammalian cells in culture.
Topics: Adrenal Cortex Hormones; Animals; Antimetabolites; Base Sequence; Carbohydrates; Cell Fusion; Cell Separation; Cells, Cultured; Cricetinae; Dactinomycin; Deoxycytidine; Drug Resistance; Epitopes; Folic Acid; Genes; Genes, Regulator; Guinea Pigs; Hot Temperature; Humans; Immunoglobulins; Mice; Mutation; Nucleosides; Phenotype; Purines; Puromycin; Rabbits; Rats; Temperature; Thymidine; Time Factors; Uracil; Uridine | 1975 |
Enzyme replacement and other biochemical approaches to the therapy of adenosine deaminase deficiency.
Topics: Adenosine; Adenosine Deaminase; B-Lymphocytes; Blood Transfusion; Cyclic AMP; Deoxyadenosines; Deoxycytidine; Erythrocyte Transfusion; Erythrocytes; Humans; Immunologic Deficiency Syndromes; Infant; Intestines; Lymphocyte Activation; Lymphocytes; Male; Nucleoside Deaminases; Pyrimidines; T-Lymphocytes; Thymidine | 1978 |
Labelling of lymphocytes with various radiosotopes for in vivo tracer studies; a review.
Topics: Amino Acids; Carbon Radioisotopes; Chromium Radioisotopes; Deoxycytidine; DNA; Idoxuridine; Isotope Labeling; Lymphocytes; Protein Biosynthesis; Radioisotopes; RNA; Technetium; Thymidine; Tritium; Uridine | 1977 |
Chemotherapeutic approaches to the treatment of the acquired immune deficiency syndrome (AIDS).
Topics: Acquired Immunodeficiency Syndrome; Adsorption; Antibodies, Viral; Antigens, Viral; Aurintricarboxylic Acid; Deltaretrovirus; Deoxycytidine; Foscarnet; Genes, Viral; Glycoproteins; Humans; Interferons; Male; Phosphonoacetic Acid; Retroviridae Infections; Reverse Transcriptase Inhibitors; Ribavirin; RNA, Viral; Suramin; Thymidine; Transcription, Genetic; Viral Proteins; Virus Replication; Zalcitabine; Zidovudine | 1986 |
Deoxyribonucleoside-induced selective modulation of cytotoxicity and mutagenesis.
Topics: Alkylating Agents; Animals; Azaguanine; Cell Line; Cell Survival; Cricetinae; Deoxyadenosines; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanosine; Deoxyribonucleosides; DNA; Drug Resistance; Drug Synergism; Floxuridine; Leukemia L1210; Lung; Methylation; Methylnitronitrosoguanidine; Mice; Mutagens; Mutation; Thymidine; Thymidylate Synthase; Thymine Nucleotides | 1985 |
Oncogenic transformation of C3H/10T1/2 Cl 8 mouse embryo fibroblasts by inhibitors of nucleotide metabolism.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Cytidine; Deoxycytidine; Deoxyribonucleotides; DNA; Embryo, Mammalian; Fibroblasts; Floxuridine; Fluorouracil; Idoxuridine; Methotrexate; Mice; Mice, Inbred C3H; Mutation; Thymidine; Trifluridine | 1985 |
Bromodeoxyuridine mutagenesis and deoxyribonucleotide pool imbalance in mammalian cells.
Topics: Animals; Base Composition; Bromodeoxyuridine; Cell Line; Cricetinae; Cytarabine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Deoxyribonucleotides; DNA; Drug Resistance; Fluorouracil; Hydroxyurea; Melanoma; Mutation; Ribonucleotide Reductases; Sister Chromatid Exchange; Thymidine | 1985 |
Formation of thymidine, cyclic deoxyguanosine and cyclic deoxycytidine adducts of the mutagen 2-bromoacrolein and their role in mutagenicity and clastogenicity.
Topics: Acrolein; Animals; Deoxycytidine; Deoxyguanosine; DNA Adducts; DNA, Single-Stranded; Mutagens; Rats; Thymidine | 1994 |
Radiosensitizing nucleosides.
Topics: Animals; Deoxycytidine; Gemcitabine; Humans; Hydroxyurea; Nucleosides; Pyrimidines; Radiation-Sensitizing Agents; Thymidine; Vidarabine | 1996 |
Solution structures of DNA duplexes containing the exocyclic lesion 3,N4-etheno-2'-deoxycytidine.
Topics: Deoxyadenosines; Deoxycytidine; Deoxyguanosine; DNA Adducts; DNA, Bacterial; Humans; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Nucleic Acid Heteroduplexes; Thymidine | 1999 |
Entecavir, FTC, L-FMAU, LdT and others.
Topics: Antiviral Agents; Arabinofuranosyluracil; Clinical Trials as Topic; Deoxycytidine; Emtricitabine; Guanine; Hepatitis B, Chronic; Humans; Randomized Controlled Trials as Topic; Thymidine | 2003 |
New treatment of chronic hepatitis B.
Topics: Adenine; Animals; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Organophosphonates; Organophosphorus Compounds; Pyrimidinones; Telbivudine; Tenofovir; Thymidine; Treatment Outcome | 2004 |
Review article: current antiviral therapy of chronic hepatitis B.
Topics: Adenine; Antiviral Agents; Carcinoma, Hepatocellular; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Cirrhosis; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Virus Replication | 2008 |
[Nucleoside and nucleotide analogs in the treatment of chronic hepatitis B].
Topics: Adenine; Antiviral Agents; Clinical Trials as Topic; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Genotype; Guanine; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Multicenter Studies as Topic; Nucleosides; Organophosphonates; Pyrimidinones; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Treatment Outcome; Virus Replication | 2008 |
[Clinical management of patients with chronic hepatitis B virus infection].
Topics: Adenine; Antiviral Agents; Biopsy; Combined Modality Therapy; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Female; Genotype; Guanine; Hepatitis B Antibodies; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Interferon-alpha; Lamivudine; Liver; Liver Transplantation; Male; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Virus Replication | 2008 |
[Hepatitis B in patients with HIV infection].
Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; Comorbidity; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B; Hepatitis B Vaccines; Hepatitis B virus; HIV; HIV Infections; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Virus Replication | 2008 |
The impact of human immunodeficiency virus on viral hepatitis.
Topics: Adenine; Antiviral Agents; Deoxycytidine; Disease Progression; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B; Hepatitis C; Hepatitis Viruses; HIV Infections; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2011 |
[New drugs of treatment of patients with chronic hepatitis B].
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Emtricitabine; Hepatitis B, Chronic; Humans; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2012 |
Thymidine kinase 2 enzyme kinetics elucidate the mechanism of thymidine-induced mitochondrial DNA depletion.
Topics: Deoxycytidine; DNA, Mitochondrial; Humans; Kinetics; Mitochondrial Diseases; Mitochondrial Proteins; Mutation; Phosphorylation; Thymidine; Thymidine Kinase | 2014 |
5 trial(s) available for thymidine and deoxycytidine
| Article | Year |
|---|---|
An in vitro method which assesses corneal epithelial toxicity due to antineoplastic, preservative and antimicrobial agents.
Topics: Adult; Aged; Aminoglycosides; Animals; Antineoplastic Agents; Antiviral Agents; Cells, Cultured; Cornea; Cytarabine; Deoxycytidine; Double-Blind Method; Epithelium; Female; Hodgkin Disease; Humans; Keratitis; Leukemia; Male; Middle Aged; Preservatives, Pharmaceutical; Rabbits; Thymidine; Toxicology | 1989 |
Progress in antiviral drug and vaccine development assessed at international AIDS conference.
Topics: Acquired Immunodeficiency Syndrome; Animals; Antiviral Agents; Clinical Trials as Topic; Deoxycytidine; Drug Evaluation; Drug Therapy, Combination; Humans; Ribavirin; Thymidine; Viral Vaccines; Zalcitabine; Zidovudine | 1987 |
AIDS. Treatment strategies and the Minnesota AIDS Clinical Trials Unit.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Deoxycytidine; Humans; Opportunistic Infections; Thymidine; Zalcitabine; Zidovudine | 1988 |
[Azidothymidine and HIV infection].
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Antiviral Agents; Clinical Trials as Topic; Deoxycytidine; Drug Interactions; Humans; Thymidine; Zalcitabine; Zidovudine | 1987 |
[Efficacy and safety of TAM-sparing antiretroviral regimens in naïve HIV-positive patients].
Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; Deoxycytidine; Dideoxynucleosides; Drug Therapy, Combination; Emtricitabine; Female; HIV Infections; HIV-1; Humans; Hyperinsulinism; Hyperlipidemias; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Prospective Studies; Tenofovir; Thymidine; Treatment Outcome; Young Adult | 2009 |
369 other study(ies) available for thymidine and deoxycytidine
| Article | Year |
|---|---|
Synthesis and biological activities of some uronic acids, uronates, uronamides, and urononitriles of pyrimidine nucleosides.
Topics: Animals; Cell Division; Cells, Cultured; Chick Embryo; Pyrimidine Nucleosides; Sarcoma 180; Simplexvirus; Streptococcus; Structure-Activity Relationship; Substrate Specificity; Thymidine Kinase; Thymidylate Synthase; Uronic Acids; Virus Replication | 1978 |
Synthesis and in vitro evaluation of some modified 4-thiopyrimidine nucleosides for prevention or reversal of AIDS-associated neurological disorders.
Topics: AIDS Dementia Complex; Animals; Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Chemistry, Physical; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Humans; Kinetics; Molecular Structure; Phosphorylation; Pyrimidine Nucleosides; Rabbits; Stavudine; T-Lymphocytes; Thymidine Kinase; Thymus Gland; Zidovudine | 1990 |
Acetylenic nucleosides. 4. 1-beta-D-arabinofuranosyl-5-ethynylcytosine. Improved synthesis and evaluation of biochemical and antiviral properties.
Topics: Antiviral Agents; Cytarabine; Deamination; Phosphorylation; Simplexvirus | 1987 |
3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents.
Topics: Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Cytopathogenic Effect, Viral; Deoxyribonucleosides; HIV; Humans; Structure-Activity Relationship; T-Lymphocytes; Virus Replication | 1987 |
Synthesis and biological activity of a novel adenosine analogue, 3-beta-D-ribofuranosylthieno[2,3-d]pyrimidin-4-one.
Topics: Adenosine; Adenosine Kinase; Animals; Antineoplastic Agents; Biotransformation; In Vitro Techniques; Leukemia L1210; Mice; Pyrimidine Nucleosides | 1985 |
Bis(m-nitrophenyl) and bis(p-nitrophenyl) esters and the phosphorodiamidate of thymidine 5'-phosphate as potential sources of intracellular thymidine 5'-phosphate in mouse cells in culture.
Topics: Amides; Animals; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; DNA; Hydrolysis; Kinetics; L Cells; Mice; Nitrobenzenes; Phosphoric Acids; Spectrophotometry, Ultraviolet; Thymidine Kinase; Thymidine Monophosphate; Thymine Nucleotides; Tritium | 1984 |
Deoxyribonucleoside kinases activate nucleoside antibiotics in severely pathogenic bacteria.
Topics: Animals; Anti-Bacterial Agents; Deoxycytidine; Female; Gemcitabine; Humans; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Molecular Sequence Data; Nucleosides; Phosphotransferases (Alcohol Group Acceptor); Staphylococcal Infections; Staphylococcus aureus; Streptococcal Infections; Streptococcus pyogenes | 2007 |
Kinetic parameters and recognition of thymidine analogues with varying functional groups by thymidine phosphorylase.
Topics: Kinetics; Molecular Structure; Structure-Activity Relationship; Substrate Specificity; Thymidine; Thymidine Phosphorylase | 2008 |
Synthesis of fluorescent nucleoside analogs as probes for 2'-deoxyribonucleoside kinases.
Topics: Animals; Drosophila melanogaster; Fluorescent Dyes; Nucleosides; Phosphotransferases (Alcohol Group Acceptor) | 2010 |
Varying effects of deoxynucleosides on the incorporation of thymidine into the DNA of monolayer and suspension cultures.
Topics: Animals; Ascites; Bone Marrow; Bone Marrow Cells; Cell Survival; Cells, Cultured; Deoxycytidine; Deoxyuridine; DNA; HeLa Cells; Hydrogen-Ion Concentration; Leukemia L1210; Lymphocytes; Neoplasms, Experimental; Thymidine | 1977 |
Deoxypyrimidine nucleoside metabolism in varicella-zoster virus-infected cells.
Topics: Cell Line; Cytidine; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; Enzyme Induction; Herpesvirus 3, Human; Humans; Hydrogen-Ion Concentration; Molecular Weight; Thymidine; Thymidine Kinase | 1978 |
Effects of cytosine arabinoside on the incorporation of pyrimidine nucleosides into hamster cells transformed by herpes simplex type 1 and type 2 viruses and by human cytomegalovirus.
Topics: Animals; Cell Line; Cell Transformation, Viral; Cricetinae; Cytarabine; Cytomegalovirus; Deoxycytidine; Humans; Phosphorylation; Pyrimidine Nucleosides; Simplexvirus; Thymidine | 1979 |
Comparative studies of the cytostatic action and metabolism of 5-azacytidine and 5,6-dihydro-5-azacytidine.
Topics: Animals; Azacitidine; Cell Division; Cells, Cultured; Cytidine; Cytidine Deaminase; Deoxycytidine; Drug Synergism; Kinetics; Leukemia L1210; Oxidative Phosphorylation; Tetrahydrouridine; Thymidine; Uridine | 1977 |
Incorporation of a potent antileukemic agent, 5-aza-2'-deoxycytidine, into DNA of cells from leukemic mice.
Topics: Animals; Azacitidine; Deoxycytidine; Epithelium; Female; Leukemia L1210; Leukemia, Experimental; Liver; Lymph Nodes; Mice; Mice, Inbred AKR; Mice, Inbred BALB C; Mice, Inbred DBA; Precancerous Conditions; Thymidine | 1977 |
Effects of 5-aza-2'-deoxycytidine on DNA synthesis in mouse lymphatic tissues.
Topics: Animals; Azacitidine; Biotransformation; Deoxycytidine; DNA; Female; Mice; Nucleoside-Phosphate Kinase; Spleen; Thymidine; Thymidine Kinase; Thymidine Monophosphate; Thymus Gland | 1978 |
Enhanced inhibition of virus DNA synthesis in hepatocytes by trifluorothymidine coupled to asialofetuin.
Topics: alpha-Fetoproteins; Animals; Bone Marrow; Deoxycytidine; DNA; DNA, Viral; Ectromelia virus; Ectromelia, Infectious; Female; Hepatitis, Viral, Animal; Liver; Mice; Necrosis; Thymidine; Time Factors; Trifluridine | 1979 |
Depression of DNA synthesis in mouse spleen after treatment with 5-aza-2'-deoxycytidine.
Topics: Animals; Azacitidine; Cytidine; Deoxycytidine; DNA; Female; Male; Mice; Nucleoside-Phosphate Kinase; Spleen; Thymidine; Thymidine Monophosphate | 1979 |
The pattern of lymphocytes in the thymus and spleen after labeling with 3H-thymidine and 3H-deoxycytidine.
Topics: Animals; Autoradiography; B-Lymphocytes; Deoxycytidine; Lymphocytes; Male; Mice; Spleen; T-Lymphocytes; Thymidine; Thymus Gland; Tritium | 1978 |
Clinical experiences with trifluorothymidine in herpes simplex keratitis.
Topics: Animals; Corneal Transplantation; Deoxycytidine; Female; Humans; Idoxuridine; Keratitis, Dendritic; Ointments; Ophthalmic Solutions; Postoperative Complications; Pregnancy; Rabbits; Recurrence; Thymidine; Time Factors; Trifluridine | 1979 |
Metabolism of pyrimidine deoxyribonucleosides in Neurospora crassa.
Topics: Autoradiography; Carbon Radioisotopes; Cell-Free System; Chromatography, Paper; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; Mixed Function Oxygenases; Models, Chemical; Mutation; Neurospora; Neurospora crassa; Pyrimidines; Thymidine; Thymine; Uracil | 1975 |
Increased urinary excretion of nucleic acid and nicotinamide derivatives by rats after treatment with alkylating agents.
Topics: 2-Acetylaminofluorene; Alkylating Agents; Animals; Benz(a)Anthracenes; Busulfan; Chromatography, Thin Layer; Cytarabine; Deoxycytidine; Dichlorvos; Dimethylnitrosamine; Ethyl Methanesulfonate; Female; Fluorouracil; Hydrocarbons, Brominated; Mechlorethamine; Methylguanidine; Niacinamide; Nitrosourea Compounds; Rats; Thymidine; Uric Acid | 1975 |
Incorporation of thymidine and iodeoxyuridine in mammalian cells in vitro.
Topics: Binding, Competitive; Bromodeoxyuridine; Cell Division; Cell Line; Culture Media; Deoxycytidine; DNA; Dose-Response Relationship, Drug; Floxuridine; Idoxuridine; Kinetics; Models, Biological; Species Specificity; T-Lymphocytes; Thymidine; Trypsin | 1975 |
Methotrexate inhibition of CCRF-CEM cultures of human lymphoblasts.
Topics: Cell Division; Cell Line; Deoxycytidine; Deoxyuridine; DNA, Neoplasm; Floxuridine; Folic Acid Antagonists; Humans; Hypoxanthines; Leucovorin; Leukemia, Lymphoid; Methotrexate; Purines; Thymidine | 1975 |
Isotope-dilution studies of the effects of 5-fluorodeoxyuridine and hydroxyurea on the incorporation of deoxycytidine and thymidine by cultured thymus cells.
Topics: Animals; Cells, Cultured; Cytidine; Deoxyadenosines; Deoxycytidine; Deoxyribonucleosides; DNA Replication; Floxuridine; Hydroxyurea; Methotrexate; Rats; Thymidine; Thymus Gland | 1976 |
The effect of 5-bromodeoxyuridine on interferon production in human cells.
Topics: Bromodeoxyuridine; Cell Division; Cell Line; Deoxycytidine; Deoxyuridine; DNA; Floxuridine; Humans; Idoxuridine; Interferons; Thymidine | 1979 |
Differential action of deoxynucleosides on mammalian cell cultures infected with herpes simplex virus types 1 and 2.
Topics: Cells, Cultured; Cytopathogenic Effect, Viral; Deoxyadenosines; Deoxycytidine; Deoxyribonucleosides; Guanosine; Humans; In Vitro Techniques; Methods; Simplexvirus; Species Specificity; Thymidine; Virus Cultivation | 1975 |
Control of proliferation in mitogen responsive human peripheral blood lymphocytes: restimulation of cells stimulated by sodium periodate.
Topics: Animals; Blood; Borohydrides; Carbon Radioisotopes; Cattle; Cells, Cultured; Centrifugation, Density Gradient; Concanavalin A; Culture Media; Deoxycytidine; DNA; Fetal Blood; Humans; Lymphocyte Activation; Lymphocytes; Periodic Acid; Sodium; Thymidine; Tritium | 1975 |
Repair methylation of parental DNA in synchronized cultures of Novikoff hepatoma cells.
Topics: Animals; Bromodeoxyuridine; Carcinoma, Hepatocellular; Cell Division; Cell Line; Deoxycytidine; DNA; DNA Repair; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; Thymidine | 1975 |
Tubuloreticular structures in human lymphoid cell lines. A cell biological study.
Topics: Antigens, Viral; Bromodeoxyuridine; Cell Line; Cells, Cultured; Cytarabine; Deoxycytidine; DNA; Herpesvirus 4, Human; Humans; Inclusion Bodies; Lymphocytes; Temperature; Thymidine | 1975 |
Herpes simplex virus specified deoxypyrimidine kinase and the uptake of exogenous nucleosides by infected cells.
Topics: Cell Line; Cytidine; Deoxycytidine; DNA; Enzyme Induction; Mutation; Phosphotransferases; RNA; Simplexvirus; Thymidine; Thymidine Kinase | 1976 |
E.s.r. of spin-trapped radicals in gamma-irradiated aqueous solutions of nucleic acids and their constituents.
Topics: Cobalt Radioisotopes; Cytidine Monophosphate; Cytosine; Deoxycytidine; DNA; Electron Spin Resonance Spectroscopy; Gamma Rays; Poly U; Thymidine; Thymidine Monophosphate; Thymine; Uracil; Uridine | 1976 |
Transport and metabolism of deoxycytidine and 1-beta-D-arabinofuranosylcytosine into cultured Novikoff rat hepatoma cells, relationship to phosphorylation, and regulation of triphosphate synthesis.
Topics: Animals; Biological Transport, Active; Carcinoma, Hepatocellular; Cells, Cultured; Cytarabine; Deoxycytidine; Deoxyribonucleotides; DNA, Neoplasm; Feedback; Hydroxyurea; Liver Neoplasms; Neoplasms, Experimental; Oxidative Phosphorylation; Rats; Thymidine | 1978 |
Phosphorylation of 5-iodo-5'-amino-2',5',dideoxyuridine by herpes simplex virus type 1 encoded thymidine kinase.
Topics: Chromatography, High Pressure Liquid; Deoxycytidine; Enzyme Induction; Idoxuridine; Kinetics; Phosphorylation; Simplexvirus; Thymidine; Thymidine Kinase | 1979 |
Role of methylation in the modification and restriction of chloroplast DNA in Chlamydomonas.
Topics: Adenine; Chlamydomonas; Chloroplasts; Deoxycytidine; DNA; DNA Replication; Methylation; Thymidine | 1979 |
A differential effect of L-serine on the incorporation of 3H-deoxycytidine and 3H-thymidine into DNA of rat thymocytes.
Topics: Animals; Cells, Cultured; Deoxycytidine; DNA; Male; Rats; Serine; T-Lymphocytes; Thymidine | 1978 |
Lack of DNA synthesis inhibitory activity in an immunosuppressor obtained from spleen.
Topics: Deoxyadenosines; Deoxycytidine; Deoxyguanosine; DNA; Immunosuppressive Agents; Interphase; Lymphocytes; Mitosis; Spleen; Thymidine | 1978 |
Differences in in vitro incorporation of tritiated deoxycytidine and tritiated thymidine into human lymphocytes.
Topics: Adult; B-Lymphocytes; Deoxycytidine; Humans; In Vitro Techniques; Lipopolysaccharides; Phytohemagglutinins; Pokeweed Mitogens; Rosette Formation; T-Lymphocytes; Thymidine | 1979 |
Patterns of thymocyte labeling in vitro with tritiated thymidine and deoxycytidine, with special reference to competitive incorporation of the two deoxyribonucleosides.
Topics: Animals; Autoradiography; Binding, Competitive; Cells, Cultured; Deoxycytidine; Rabbits; T-Lymphocytes; Thymidine; Tritium | 1979 |
Mutagenesis of Chinese hamster cells is facilitated by thymidine and deoxycytidine.
Topics: Animals; Cell Line; Cricetinae; Cricetulus; Deoxycytidine; Methylnitronitrosoguanidine; Mutation; Thymidine | 1979 |
Differences in utilization of tritiated thymidine and tritiated deoxycytidine by rat lymph node cells.
Topics: Animals; Antigens, Bacterial; Autoradiography; Deoxycytidine; Female; Lymph Nodes; Rats; Thymidine; Time Factors | 1979 |
Design of species- or isozyme-specific enzyme inhibitors. 1. Effect of thymidine substituents on affinity for the thymidine site of hamster cytoplasmic thymidine kinase.
Topics: Animals; Cricetinae; Cytoplasm; Deoxycytidine; Deoxyuridine; Humans; In Vitro Techniques; Isoenzymes; Kidney; Kinetics; Methods; Mitochondria; Structure-Activity Relationship; Substrate Specificity; Thymidine; Thymidine Kinase; Thymine Nucleotides | 1979 |
The patterns of labeling of plasma cells and pyroninophilic blast cells with tritiated deoxycytidine and thymidine.
Topics: Animals; Deoxycytidine; Isotope Labeling; Lymphocytes; Male; Plasma Cells; Rabbits; Rats; Thymidine; Tritium | 1979 |
Facilitation by pyrimidine deoxyribonucleosides and hypoxanthine of mutagenic and cytotoxic effects of monofunctional alkylating agents in Chinese hamster cells.
Topics: Animals; Cell Line; Cricetinae; Cricetulus; Deoxycytidine; Drug Synergism; Hypoxanthines; Lung; Methylnitronitrosoguanidine; Mutagens; Mutation; Thymidine; Time Factors | 1979 |
Selective labeling of mesenteric lymph nodes: cell production and emigration of newly formed lymphocytes to other organs.
Topics: Animals; Cell Movement; Deoxycytidine; Lymph Nodes; Lymphoid Tissue; Mesentery; Mitosis; Swine; Thymidine | 1979 |
Effect of cytosine arabinoside triphosphate on the incorporation of 3H-thymidine in mitochondria isolated from HeLa cells.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cell-Free System; Cytarabine; Deoxycytidine; DNA, Mitochondrial; DNA, Neoplasm; Ethidium; HeLa Cells; Humans; Mitochondria; Thymidine | 1979 |
[Dynamics of 3H-thymidine and 3H-deoxycytidine incorporation into the nuclei of a rabbit kidney cell culture during the S period].
Topics: Animals; Base Sequence; Cell Nucleus; Cells, Cultured; Deoxycytidine; DNA; Mitosis; Rabbits; Thymidine | 1977 |
Mutagenicity of thymidine to cultured Chinese hamster cells.
Topics: Animals; Cell Line; Cricetinae; Deoxycytidine; Dose-Response Relationship, Drug; Hydroxyurea; Mutation; Thymidine | 1978 |
Inhibition of [3H]TdR and [3H]CdR incorporation in an established human lymphoma cell line by trypsin treatment.
Topics: Animals; Cell Line; Cell Separation; Deoxycytidine; DNA, Neoplasm; HeLa Cells; Humans; Lymphoma, Non-Hodgkin; Melanoma; Neoplasms, Experimental; Sarcoma, Experimental; Thymidine; Trypsin | 1978 |
Comparative study of human chromosome replication in primary cultures of embryonic fibroblasts and in cultures of peripheral blood leucocytes. IV. Differences in the intensity of 3H-thymidine and 3H-deoxycytidine incorporation of chromosomes in the two ty
Topics: Cells, Cultured; Chromosomes, Human; Deoxycytidine; DNA Replication; Female; Fibroblasts; Humans; Leukocytes; Male; Thymidine | 1977 |
3' deoxycytidine, like hydroxyurea, inhibits DNA synthesis without preventing the initiation of the cell cycle.
Topics: Cell Cycle; Cell Line; Deoxycytidine; DNA; Hydroxyurea; RNA; Thymidine | 1978 |
Biological and biochemical effects of bromodeoxyuridine and deoxycytidine on Syrian hamster melanoma cells.
Topics: Aminopterin; Bromodeoxyuridine; Cell Division; Cell Line; Deoxycytidine; DNA; Dose-Response Relationship, Drug; Thymidine | 1978 |
[Sister chromatid exchanges following incorporation of bromine into cytosine DNA nucleotides. I. Combined use of 5-bromdeoxycytidine and thymidine for the purpose of incorporating bromine into DNA cytosine].
Topics: Bromodeoxycytidine; Chromatids; Chromosomes, Human; Deoxycytidine; Depression, Chemical; DNA; Humans; Lymphocytes; Thymidine | 1978 |
Mutagenesis of Chinese hamster cells is facilitated by thymidine and deoxycytidine.
Topics: Cell Division; Cell Line; Cell Survival; Deoxycytidine; DNA Replication; Dose-Response Relationship, Drug; Methylnitronitrosoguanidine; Mutation; Thymidine | 1978 |
Bromodeoxyuridine mutagenesis in mammalian cells is stimulated by thymidine and suppressed by deoxycytidine.
Topics: Bromodeoxyuridine; Cell Line; Deoxycytidine; Drug Synergism; Mutation; Ribonucleotide Reductases; Thymidine | 1978 |
Effect of ionizing radiation on nucleoside metabolism in Physarum polycephalum.
Topics: Cell Cycle; Cytidine; Cytidine Triphosphate; Deoxycytidine; DNA; Gamma Rays; Nucleosides; Physarum; Thymidine | 1978 |
[Sister chromatid exchanges under bromine incorporation into DNA cytosine nucleotides. II. Utilization of 3H-deoxycytidine as a DNA cytosine precursor].
Topics: Bromodeoxycytidine; Cells, Cultured; Chromatids; Crossing Over, Genetic; Cytosine Nucleotides; Deoxycytidine; DNA; Humans; Interphase; Lymphocytes; Metaphase; Nucleic Acid Precursors; Thymidine; Time Factors; Tritium | 1978 |
Replicative bacteriophage DNA synthesis in plasmolyzed T4-infected cells: evidence for two independent pathways to DNA.
Topics: Adenosine Triphosphate; Cell Membrane Permeability; Coliphages; Deoxycytidine; Deoxyribonucleotides; DNA Replication; DNA, Viral; Escherichia coli; Magnesium; Mutation; Osmosis; Temperature; Thymidine | 1976 |
Polypyrimidine segments in Drosophila melanogaster DNA: I. Detection of a cryptic satellite containing polypyrimidine/polypurine DNA.
Topics: Cell Line; Centrifugation, Density Gradient; Chromatography, Gel; Deoxycytidine; DNA; Drosophila melanogaster; Models, Molecular; Molecular Weight; Purine Nucleotides; Pyrimidine Nucleotides; Spectrophotometry, Ultraviolet; Thymidine; Tritium | 1975 |
Induction of tubuloreticular inclusions in human lymphoma cells (Raji line) related to S-phase treatment with halogenated pyrimidines.
Topics: Autoradiography; Bromodeoxyuridine; Burkitt Lymphoma; Cell Division; Cell Line; Deoxycytidine; DNA, Neoplasm; Drug Resistance; Endoplasmic Reticulum; Idoxuridine; Lymphocytes; Thymidine | 1977 |
Inhibition of early postimplantation development of cultured mouse embryos by bromodeoxyuridine.
Topics: Animals; Blastocyst; Bromodeoxyuridine; Cell Differentiation; Deoxycytidine; DNA; Embryo, Mammalian; Female; In Vitro Techniques; Male; Mice; Pregnancy; Thymidine; Trophoblasts | 1977 |
Transport and countertransport of thymidine in ATP depleted and thymidine kinase-deficient Novikoff rat hepatoma and mouse L cells: evidence of a high Km facilitated diffusion system with wide nucleoside specificity.
Topics: Adenosine Triphosphate; Biological Transport, Active; Cell Line; Cyanides; Deoxycytidine; Diffusion; Iodoacetates; Kinetics; L Cells; Mutation; Nucleosides; Potassium; Thymidine; Thymidine Kinase | 1976 |
Deoxypyrimidineuria in the course of chemotherapy in M. Hodgkin.
Topics: Cyclophosphamide; Deoxycytidine; Deoxyuridine; Drug Therapy, Combination; Female; Hodgkin Disease; Humans; Male; Prednisone; Procarbazine; Sex Factors; Splenectomy; Thymidine; Vinblastine; Vincristine | 1976 |
Nuclear incorporation of radioactive DNA precursors and progression of cells through S. Combined radioautographic and cytophotometric studies on normal and leukaemic bone marrow and thoracic duct lymph cells of man.
Topics: Aged; Bone Marrow; Bone Marrow Cells; Cell Nucleus; Child; Child, Preschool; Deoxycytidine; DNA; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Lymphocytes; Male; Mitosis; Scleroderma, Systemic; Thymidine; Tritium | 1975 |
Dependency of sister chromatid exchange in T- and B-cells on the incorporation of deoxyribonucleosides into chromosomal DNA.
Topics: Autoradiography; B-Lymphocytes; Bromodeoxyuridine; Cell Line; Cells, Cultured; Chromatids; Crossing Over, Genetic; Deoxycytidine; Deoxyribonucleotides; DNA; Leukemia, Lymphoid; Mitosis; T-Lymphocytes; Thymidine; Thymidine Kinase | 1976 |
Relationship between virus multiplication and culture cells synchronized by excess thymidine treatment. V. Effect of chikungunya virus infection upon the host cell cycle.
Topics: Amnion; Antigens, Viral; Autoradiography; Cell Line; Chikungunya virus; Clone Cells; Colchicine; Deoxycytidine; DNA, Viral; Fluorescent Antibody Technique; Humans; Mitosis; RNA, Viral; Thymidine; Tritium; Uridine | 1975 |
Reaction of ribonucleosides and deoxynucleosides with copper(II) acetate.
Topics: Acetates; Chemical Phenomena; Chemistry; Copper; Cytidine; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; Ribonucleosides; Spectrum Analysis; Thymidine; Uridine | 1975 |
Metabolism of deoxycytidine, thymine, and deoxythymidine in the hamster.
Topics: Age Factors; Animals; Carbon Dioxide; Cricetinae; Deoxycytidine; DNA; Dose-Response Relationship, Drug; Liver; Male; Thymidine; Thymine; Time Factors | 1975 |
The inhibitory effect of theophylline on the incorporation of 3H-deoxycytidine and 3H-thymidine into thymocyte DNA.
Topics: Animals; Cells, Cultured; Deoxycytidine; Depression, Chemical; DNA; Lymphocytes; Male; Rats; Theophylline; Thymidine; Thymus Gland; Time Factors | 1975 |
Urine excretion of nucleosides in Hodgkin's disease treated by combined chemotherapy.
Topics: Cyclophosphamide; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; Drug Therapy, Combination; Hodgkin Disease; Humans; Prednisolone; Thymidine; Time Factors; Vinblastine | 1975 |
A comparative study on the uptake in vitro of [3H]thymidine, [131I]5-iodo-2'-deoxyuridine and [3H]deoxycytidine in mouse spleen cells using double isotope autoradiography.
Topics: Animals; Autoradiography; Deoxycytidine; Idoxuridine; Iodine Radioisotopes; Lymphocytes; Male; Mice; Spleen; Thymidine; Tritium | 1975 |
Mechanisms of action of 6-thioguanine, 6-mercaptopurine, and 8-azaguanine.
Topics: Azaguanine; Azauridine; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Cytarabine; Deoxycytidine; DNA, Neoplasm; Guanine; Hypoxanthines; Imidazoles; Mercaptopurine; Methylthioinosine; Purines; RNA, Neoplasm; Thioguanine; Thymidine | 1975 |
Effect of calcium and magnesium on deoxyribonucleic acid synthesis in rat parathyroid glands in vitro.
Topics: Animals; Autoradiography; Calcium; Deoxycytidine; DNA; Humans; Hydroxyurea; Hyperplasia; Kidney; Kidney Failure, Chronic; L Cells; Liver; Magnesium; Male; Mice; Organ Culture Techniques; Parathyroid Diseases; Parathyroid Glands; Rats; Thymidine | 1975 |
Inhibition of myogenesis in a rat myoblast line by 5-bromodeoxyuridine.
Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Cell Fusion; Cell Line; Deoxycytidine; Muscle Development; Rats; Templates, Genetic; Thymidine | 1975 |
Deficiency of joining of Okazaki-type fragments in absence of cellular protein synthesis.
Topics: Amino Acids; Animals; Carcinoma, Ehrlich Tumor; Centrifugation, Density Gradient; Deoxycytidine; DNA Replication; DNA, Neoplasm; Kinetics; Mice; Neoplasm Proteins; Protein Biosynthesis; Thymidine; Time Factors; Transcription, Genetic | 1975 |
Preferential incorporation of 3H-deoxycytidine into chicken bursal cells. Comparison of radiolabelled nucleosides as lymphoid cell markers in chickens and mice.
Topics: Animals; Bursa of Fabricius; Chickens; Deoxycytidine; Deoxyuridine; DNA; Female; Intestinal Mucosa; Lymph Nodes; Mice; Spleen; Thymidine; Thymus Gland | 1975 |
Changes in pyrimidine metabolism of rat lymphocytes cultured with PHA.
Topics: Cell Division; Cells, Cultured; Deoxycytidine; Lectins; Lymphocyte Activation; Lymphocytes; Mitosis; Thymidine | 1975 |
Reactivation of chick erythrocyte nuclei in BHK derived cells with multiple biochemical lesions.
Topics: Adenine; Adenine Phosphoribosyltransferase; Adenosine; Cell Fusion; Cell Line; Cell Nucleolus; Cell Nucleus; Deoxycytidine; DNA; Erythrocytes; Guanosine; Hybrid Cells; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; RNA; Thymidine; Uridine | 1975 |
Lack of specific correlation of the deoxycytidine triphosphate pool level with rate of DNA synthesis.
Topics: Cell Line; Cytidine; Cytosine Nucleotides; Deoxycytidine; Deoxyribonucleotides; Deoxyuridine; DNA Replication; Thymidine | 1975 |
The effect of external deoxyribonucleosides on deoxyribonucleoside triphosphate concentrations in human lymphocytes.
Topics: Animals; Cattle; Cells, Cultured; Deoxycytidine; Deoxyribonucleosides; Deoxyribonucleotides; DNA; Humans; Kinetics; Lectins; Lymphocytes; Stimulation, Chemical; Thymidine | 1975 |
Antileukemic effects of pseudoisocytidine, a new synthetic pyrimidine C-nucleoside.
Topics: Animals; Cell Line; Cells, Cultured; Cytidine; Deoxycytidine; Drug Evaluation, Preclinical; Isomerism; Leukemia, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Thymidine | 1976 |
Preferential labeling of rat lymphocytes with a rapid rate of turnover by tritiated deoxycytidine.
Topics: Animals; Autoradiography; Bone Marrow; Bone Marrow Cells; Cytosine; Deoxycytidine; DNA; Lymph Nodes; Lymphocytes; Male; Peyer's Patches; Rats; Spleen; Thymidine; Thymine; Thymus Gland | 1976 |
The effect of 5-bromodeoxyuridine on cell division and differentiation of preimplantation mouse embryos.
Topics: Animals; Blastocyst; Bromodeoxyuridine; Cell Count; Cell Differentiation; Cell Division; Cells, Cultured; Deoxycytidine; Embryo, Mammalian; Mice; Thymidine | 1976 |
Selective assays for thymidine kinase 1 and 2 and deoxycytidine kinase and their activities in extracts from human cells and tissues.
Topics: Arabinonucleosides; Cladribine; Deoxycytidine; Deoxycytidine Kinase; Humans; Isoenzymes; Kinetics; Leukemia; Leukocytes; Mitochondria; Organ Specificity; Phosphorylation; Radioisotope Dilution Technique; Reference Values; Substrate Specificity; Thymidine; Thymidine Kinase; Tritium; Tumor Cells, Cultured; Zidovudine | 1992 |
Effects of Captan on DNA and DNA metabolic processes in human diploid fibroblasts.
Topics: Captan; Carbon Radioisotopes; Cells, Cultured; Clone Cells; Deoxycytidine; Diploidy; DNA; DNA Repair; DNA Replication; Fibroblasts; Humans; Kinetics; Male; Mutagens; Protein Biosynthesis; Proteins; RNA; Skin; Thymidine; Tritium | 1992 |
Cell kinetics of the rat corneal epithelium.
Topics: Animals; Cornea; Deoxycytidine; DNA; Epithelial Cells; Female; Kinetics; Methotrexate; Mitosis; Mitotic Index; Rats; Rats, Wistar; Thymidine | 1992 |
Identification of a broad-specificity nucleoside transporter with affinity for the sugar moiety in Giardia intestinalis trophozoites.
Topics: Adenosine; Animals; Binding, Competitive; Biological Transport; Carrier Proteins; Deoxycytidine; Furans; Giardia lamblia; Guanosine; Kinetics; Membrane Proteins; Nucleoside Transport Proteins; Nucleosides; Thymidine | 1992 |
Enhanced expression of stomach cancer antigen derived from malignantly transformed bloom syndrome cells previously labeled with bromodeoxyuridine.
Topics: Antibodies, Neoplasm; Antigens, Neoplasm; Bloom Syndrome; Blotting, Western; Bromodeoxyuridine; Cell Line, Transformed; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Sister Chromatid Exchange; Stomach Neoplasms; Thymidine | 1992 |
Compartmentation of dCTP pools disappears after hydroxyurea or araC treatment in lymphocytes.
Topics: Cytarabine; Deoxycytidine; Deoxycytosine Nucleotides; DNA; G1 Phase; Humans; Hydroxyurea; Lymphocytes; Palatine Tonsil; Phospholipids; S Phase; Thymidine | 1992 |
Synthesis and biological activity of 2'-deoxy-4'-thio pyrimidine nucleosides.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Carcinoma, Squamous Cell; Chemical Phenomena; Chemistry; Cytomegalovirus; Deoxycytidine; Deoxyuridine; Humans; Leukemia L1210; Leukemia, T-Cell; Mice; Simplexvirus; Thionucleosides; Thiouridine; Thymidine; Tumor Cells, Cultured | 1991 |
Broad-spectrum antiviral and cytocidal activity of cyclopentenylcytosine, a carbocyclic nucleoside targeted at CTP synthetase.
Topics: Adenosine; Amides; Antiviral Agents; Azauridine; Carbon-Nitrogen Ligases; Cell Division; Cytarabine; Cytidine; Deoxycytidine; Drug Synergism; Fluorouracil; HeLa Cells; Humans; Ligases; Nucleosides; Pyrazoles; Ribavirin; Ribonucleosides; Ribose; Thymidine; Tumor Cells, Cultured; Uracil; Virus Replication; Viruses | 1991 |
A single lymphocyte culture for fragile X induction and prometaphase chromosome analysis.
Topics: Adolescent; Adult; Cells, Cultured; Child; Child, Preschool; Chromosome Fragility; Deoxycytidine; Female; Fragile X Syndrome; Gene Expression; Humans; Lymphocytes; Male; Metaphase; Middle Aged; Thymidine; X Chromosome | 1991 |
Deoxycytidine is salvaged not only into DNA but also into phospholipid precursors. III. dCOP-diacylglycerol formation in tonsillar lymphocytes.
Topics: Chlorpromazine; Chromatography, Thin Layer; Cytarabine; Cytidine Diphosphate Diglycerides; Deoxycytidine; DNA; Humans; Infant; Kinetics; Lymphocytes; Palatine Tonsil; Phosphatidylinositols; Thymidine | 1991 |
Deoxyadenosine reverses hydroxyurea inhibition of vaccinia virus growth.
Topics: Adenine; Adenosine Deaminase Inhibitors; Adenosine Triphosphate; Antiviral Agents; Cells, Cultured; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Hydroxyurea; Ribonucleotide Reductases; Thymidine; Vaccinia virus; Viral Plaque Assay; Virus Replication | 1991 |
Radiosensitization of human T-cell leukemia by thymidine and 41.8 degrees C hyperthermia in vitro.
Topics: Cell Survival; Cesium Radioisotopes; Combined Modality Therapy; Deoxycytidine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Humans; Hyperthermia, Induced; Leukemia-Lymphoma, Adult T-Cell; Radiation Tolerance; Thymidine; Tumor Cells, Cultured | 1991 |
Chromosome aberration dosimetry: addition of thymidine, an interesting mean to increase the number of dividing cells.
Topics: Cell Division; Cells, Cultured; Chromosome Aberrations; Colchicine; Culture Media; Deoxycytidine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Gamma Rays; Humans; Mitotic Index; Thymidine | 1991 |
Effect of 3'-deoxythymidin-2'-ene (d4T) on nucleoside metabolism in H9 cells.
Topics: Amino Acids; Cell Division; Cell Survival; Cells, Cultured; Cytidine; Deoxycytidine; Dideoxynucleosides; Humans; Nucleosides; Stavudine; Thymidine; Thymidine Kinase; Uridine | 1990 |
Photodynamic methods for oxy radical-induced DNA damage.
Topics: Chromatography, Thin Layer; Deoxycytidine; DNA Damage; Free Radicals; Oxidation-Reduction; Photochemistry; Thymidine; Ultraviolet Rays | 1990 |
In vitro reactions of glycidol with pyrimidine bases in calf thymus DNA.
Topics: 1-Propanol; Animals; Cattle; Chromatography, High Pressure Liquid; Deoxycytidine; Deoxyuridine; DNA; Epoxy Compounds; Ethers, Cyclic; Hydrogen-Ion Concentration; Propanols; Pyrimidines; Thymidine; Thymus Gland | 1990 |
Synchronization culture of amniotic fluid cells using excess thymidine block followed by deoxycytidine release and its application to high-resolution banding analysis of chromosomes.
Topics: Amniotic Fluid; Cell Cycle; Cells, Cultured; Chromosome Aberrations; Chromosome Banding; Chromosome Disorders; Chromosomes; Chromosomes, Human, Pair 18; Chromosomes, Human, Pair 4; Chromosomes, Human, Pair 9; Dactinomycin; Deoxycytidine; Ethidium; Female; Humans; Male; Mitotic Index; Prenatal Diagnosis; Syndrome; Thymidine; Time Factors; Translocation, Genetic | 1990 |
Tolerance to bromodeoxyuridine in a thymidine-requiring strain of Bacillus subtilis.
Topics: Bacillus subtilis; Bromodeoxyuridine; Centrifugation, Density Gradient; Deoxycytidine; DNA Replication; DNA, Bacterial; Genetic Markers; Mutation; RNA, Bacterial; Thymidine; Thymidine Kinase; Thymine Nucleotides | 1986 |
Potent and selective in vitro activity of 3'-deoxythymidin-2'-ene (3'-deoxy-2',3'-didehydrothymidine) against human immunodeficiency virus.
Topics: Antiviral Agents; Deoxycytidine; HIV; Humans; Monocytes; Retroviridae Proteins; RNA-Directed DNA Polymerase; Stavudine; Thymidine; Virus Replication; Zidovudine | 1987 |
[Comparative study of the genetic effect of various tritium compounds in male mice].
Topics: Animals; Deoxycytidine; Glucose; Glycine; Lysine; Male; Mice; Mutagens; Sperm Head; Testis; Thymidine; Translocation, Genetic; Tritium | 1989 |
Differential patterns of intracellular metabolism of 2',3'-didehydro-2',3'-dideoxythymidine and 3'-azido-2',3'-dideoxythymidine, two potent anti-human immunodeficiency virus compounds.
Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Deoxycytidine; Deoxyribonucleotides; Dideoxynucleosides; Dose-Response Relationship, Drug; HIV; Humans; Mice; Phosphorylation; Sarcoma Viruses, Murine; Solubility; Stavudine; Thymidine; Zidovudine | 1989 |
Effect of phosphorothioate homo-oligodeoxynucleotides on herpes simplex virus type 2-induced DNA polymerase.
Topics: Animals; Binding, Competitive; Cattle; Deoxyadenosines; Deoxycytidine; Deoxyribonucleotides; DNA; Enzyme Induction; Exodeoxyribonuclease V; Exodeoxyribonucleases; Herpesvirus 4, Human; Humans; Kinetics; Nucleic Acid Synthesis Inhibitors; Simplexvirus; Templates, Genetic; Thionucleotides; Thymidine | 1989 |
[Relationship between Ara-C sensitivity of leukemic-colony forming units (L-CFU) and [3H] deoxycytidine suicide test of L-CFU].
Topics: Adult; Aged; Cell Survival; Cytarabine; Deoxycytidine; Female; Humans; Leukemia; Male; Middle Aged; Neoplastic Stem Cells; Thymidine; Tritium; Tumor Stem Cell Assay | 1989 |
The synthesis of 2-pyrimidinone nucleosides and their incorporation into oligodeoxynucleotides.
Topics: Base Sequence; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Circular Dichroism; Deoxycytidine; Hot Temperature; Hydrazines; Hydrolysis; Methylation; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Osmolar Concentration; Oxidation-Reduction; Pyrimidine Nucleosides; Thymidine | 1989 |
5-Halogeno-3'-fluoro-2',3'-dideoxyuridines as inhibitors of human immunodeficiency virus (HIV): potent and selective anti-HIV activity of 3'-fluoro-2',3'-dideoxy-5-chlorouridine.
Topics: Antiviral Agents; Cell Transformation, Viral; Deoxycytidine; Dideoxynucleosides; Halogens; HIV; Phosphorylation; Thymidine; Uridine | 1989 |
Detection of thymidine kinase activity using an assay based on the precipitation of nucleoside monophosphates with lanthanum chloride.
Topics: Bromodeoxycytidine; Cells, Cultured; Chemical Precipitation; Cytosol; Deoxycytidine; Idoxuridine; Lanthanum; Nucleotides; Thymidine; Thymidine Kinase | 1989 |
Deoxyribonucleoside triphosphate pools in regenerating rat liver: effect of hydroxyurea and exogenous deoxypyrimidines.
Topics: Animals; Deoxycytidine; Deoxyribonucleotides; DNA; Hepatectomy; Hydroxyurea; Kinetics; Liver; Liver Regeneration; Male; Rats; Rats, Inbred Strains; Reference Values; Thymidine | 1989 |
Follicular cells of tonsils metabolise more deoxycytidine than other cell populations.
Topics: Cell Differentiation; Cell Separation; Child; Child, Preschool; Deoxycytidine; Deoxycytidine Kinase; DNA Replication; Humans; Lymphocytes; Palatine Tonsil; Phosphorylation; Thymidine | 1989 |
Deoxycytidine is salvaged not only into DNA but also into phospholipid precursors. II. Ara-C does not inhibit the later process in lymphoid cells.
Topics: AraC Transcription Factor; Bacterial Proteins; Choline; Cytarabine; Deoxycytidine; DNA; Humans; Infant; Lymphoid Tissue; Lymphoma; Phospholipids; Repressor Proteins; Thymidine; Transcription Factors; Tumor Cells, Cultured | 1989 |
Increased sister-chromatid exchanges (SCEs) and chromosomal fragilities by BrdU in a human mutant B-lymphoblastoid cell line.
Topics: B-Lymphocytes; Bromodeoxyuridine; Cell Line, Transformed; Chromosome Fragility; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 9; Deoxycytidine; Dose-Response Relationship, Radiation; Humans; Metaphase; Mutation; Sister Chromatid Exchange; Thymidine | 1989 |
Reduced DNA damage induced in human melanoma cells by dacarbazine in the presence of deoxyribonucleosides.
Topics: Dacarbazine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; DNA Damage; DNA, Neoplasm; Humans; Melanoma; Thymidine | 1989 |
Sensitive and rapid assay on MT-4 cells for detection of antiviral compounds against the AIDS virus.
Topics: Antigens, Viral; Antiviral Agents; Cell Line; Cell Survival; Cytopathogenic Effect, Viral; Deoxycytidine; Flow Cytometry; Fluorescent Antibody Technique; HIV; Humans; Thymidine; Zalcitabine; Zidovudine | 1987 |
Failure of dideoxynucleosides to inhibit human immunodeficiency virus replication in cultured human macrophages.
Topics: Adenosine Kinase; Cell Line; Deoxyadenosines; Deoxycytidine; Deoxycytidine Kinase; Dideoxyadenosine; HIV; Humans; Macrophages; Phosphorylation; T-Lymphocytes; Thymidine; Thymidine Kinase; Uridine Kinase; Virus Replication; Zalcitabine; Zidovudine | 1987 |
Differential affinities of pyrimidine nucleoside analogues for deoxythymidine and deoxycytidine kinase determine their incorporation into murine leukemia L1210 cells.
Topics: Animals; Cells, Cultured; Deoxycytidine; Deoxycytidine Kinase; Leukemia L1210; Mice; Nucleic Acids; Phosphotransferases; Pyrimidine Nucleosides; Thymidine; Thymidine Kinase | 1987 |
2',3'-Dideoxycytidine: regulation of its metabolism and anti-retroviral potency by natural pyrimidine nucleosides and by inhibitors of pyrimidine nucleotide synthesis.
Topics: Animals; Antiviral Agents; Deoxycytidine; Deoxycytosine Nucleotides; HIV; Humans; Leukemia L1210; Mice; Phosphorylation; Pyrimidine Nucleosides; Pyrimidine Nucleotides; Pyrimidines; Thymidine; Tritium; Tumor Cells, Cultured; Zalcitabine | 1987 |
The in vitro and in vivo anti-retrovirus activity, and intracellular metabolism of 3'-azido-2',3'-dideoxythymidine and 2',3'-dideoxycytidine are highly dependent on the cell species.
Topics: Animals; Antiviral Agents; Cell Line; Deoxycytidine; HIV; Humans; Mice; Mice, Inbred C3H; Moloney murine sarcoma virus; Retroviridae; Thymidine; Zalcitabine; Zidovudine | 1988 |
Therapy for neurological involvement in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Blood-Brain Barrier; Central Nervous System Diseases; Deoxycytidine; Humans; Immunotherapy; Molecular Biology; Retroviridae; Thymidine; Zalcitabine; Zidovudine | 1988 |
Inhibition of infectivity and replication of HIV-2 and SIV in helper T-cells by 2',3'-dideoxynucleosides in vitro.
Topics: Cytopathogenic Effect, Viral; Deoxyadenosines; Deoxycytidine; Dideoxyadenosine; HIV; In Vitro Techniques; Nucleosides; Retroviridae; T-Lymphocytes, Helper-Inducer; Thymidine; Viral Proteins; Virus Replication; Zalcitabine; Zidovudine | 1988 |
Anti-retrovirus activity of 3'-fluoro- and 3'-azido-substituted pyrimidine 2',3'-dideoxynucleoside analogues.
Topics: Animals; Antimetabolites; Antiviral Agents; Cell Division; Deoxycytidine; Deoxycytidine Kinase; Dideoxynucleosides; DNA; HIV; Kinetics; Mice; Phosphorylation; Pyrimidine Nucleosides; Retroviridae; Thymidine; Thymidine Kinase; Zalcitabine | 1988 |
Synergistic interaction of 2',3'-dideoxycytidine and recombinant interferon-alpha-A on replication of human immunodeficiency virus type 1.
Topics: Antiviral Agents; Cell Line; Deoxycytidine; Drug Synergism; HIV; Humans; Interferon Type I; Leukocytes; Recombinant Proteins; Thymidine; Virus Replication; Zalcitabine; Zidovudine | 1988 |
Restricted transport of 3'-azido-3'-deoxythymidine and dideoxynucleosides through the blood-brain barrier.
Topics: Animals; Antiviral Agents; Blood-Brain Barrier; Deoxyadenosines; Deoxycytidine; Dideoxyadenosine; Liver; Male; Rats; Rats, Inbred Strains; Thymidine; Zalcitabine; Zidovudine | 1988 |
Deoxycytidine reverses inhibition of morphogenesis by thymidine in young chick blastoderm.
Topics: Animals; Autoradiography; Blastoderm; Chick Embryo; Deoxycytidine; Morphogenesis; Thymidine; Tritium | 1986 |
Phase I studies of 2',3'-dideoxycytidine in severe human immunodeficiency virus infection as a single agent and alternating with zidovudine (AZT).
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Complex; Deoxycytidine; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; HIV; Humans; Male; Middle Aged; Thymidine; Zalcitabine; Zidovudine | 1988 |
Single-step selection of mammalian cell mutants deficient in CTP synthetase.
Topics: Animals; Carbon-Nitrogen Ligases; Cell Line; Cell Separation; Cricetinae; Cytidine; Deoxycytidine; DNA; Ligases; Mutation; Thymidine; Uridine | 1989 |
Synergistic inhibition of anatid herpesvirus replication by acyclovir and phosphonocompounds.
Topics: Acyclovir; Animals; Deoxycytidine; Drug Interactions; Drug Resistance, Microbial; Foscarnet; Herpesviridae; Mutation; Organophosphorus Compounds; Phosphonoacetic Acid; Thymidine; Virus Replication | 1987 |
5-fluorodeoxyuridine decreases the effect of arabinofuranosyl-cytosine in undifferentiated human B lymphocytes.
Topics: B-Lymphocytes; Centrifugation, Density Gradient; Child, Preschool; Cytarabine; Deoxycytidine; DNA; Floxuridine; Humans; T-Lymphocytes; Thymidine; Tritium | 1988 |
Inhibition of HSV-transformed murine cells by nucleoside analogs, 2'-NDG and 2'-nor-cGMP: mechanisms of inhibition and reversal by exogenous nucleosides.
Topics: Acyclovir; Animals; Cell Division; Cell Line; Cell Survival; Cell Transformation, Viral; Cyclic GMP; Deoxycytidine; Deoxyguanosine; Ganciclovir; Guanine; Mice; Organophosphorus Compounds; Simplexvirus; Thymidine; Thymidine Kinase | 1985 |
Multisubstrate analogs for deoxynucleoside kinases. Use in novel affinity media applied to resolution of Lactobacillus enzymes.
Topics: Animals; Binding Sites; Chromatography, Affinity; Deoxyadenosines; Deoxycytidine; Deoxycytidine Kinase; Deoxyguanosine; Enzyme Activation; Lactobacillus acidophilus; Oligodeoxyribonucleotides; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Thymidine; Thymidine Kinase | 1985 |
Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides.
Topics: Antiviral Agents; Carbohydrate Conformation; Cell Division; Cytopathogenic Effect, Viral; Deltaretrovirus; Deoxyadenosines; Deoxycytidine; Deoxyribonucleosides; Dideoxyadenosine; Dideoxynucleosides; Gene Products, gag; Humans; Lymphocyte Activation; Mitogens; Retroviridae Proteins; Structure-Activity Relationship; T-Lymphocytes; Thymidine; Vidarabine; Zalcitabine | 1986 |
Plaque autoradiography assay for the detection and quantitation of thymidine kinase-deficient and thymidine kinase-altered mutants of herpes simplex virus in clinical isolates.
Topics: Acyclovir; Autoradiography; Bromodeoxycytidine; Deoxycytidine; Herpes Simplex; Humans; Mutation; Simplexvirus; Thymidine; Thymidine Kinase; Viral Plaque Assay | 1985 |
Antiviral activity of 2',3'-dideoxycytidin-2'-ene (2',3'-dideoxy-2',3'-didehydrocytidine) against human immunodeficiency virus in vitro.
Topics: Antiviral Agents; Deoxycytidine; Fluorescence; HIV; Humans; In Vitro Techniques; Monocytes; Thymidine; Zalcitabine; Zidovudine | 1987 |
Pharmacological inhibition of in vitro infectivity of human T lymphotropic virus type I.
Topics: Deltaretrovirus; Deoxycytidine; DNA, Viral; Humans; Lymphocyte Activation; T-Lymphocytes, Helper-Inducer; Tetanus Toxoid; Thymidine; Virus Replication; Zalcitabine; Zidovudine | 1987 |
Disturbances in DNA precursor metabolism associated with exposure to an inhibitor of poly(ADP-ribose) synthetase.
Topics: Benzamides; Chromatography, High Pressure Liquid; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; DNA; Humans; Nucleosides; Poly(ADP-ribose) Polymerase Inhibitors; Thymidine | 1986 |
Chemical structure of 3-carbethoxypsoralen-DNA photoadducts.
Topics: Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Deoxycytidine; Deoxyuridine; DNA; Furocoumarins; Light; Photochemistry; Spectrometry, Fluorescence; Stereoisomerism; Thymidine | 1986 |
DNA synthesis and nucleoside metabolism in human tonsillar lymphocyte subpopulations.
Topics: Antigens, Differentiation; Child; Child, Preschool; Deoxycytidine; Deoxycytidine Kinase; Dithiothreitol; DNA; DNA-Directed DNA Polymerase; Humans; Lymphocytes; Nucleosides; Palatine Tonsil; Thymidine; Thymidine Kinase | 1988 |
O-Alkyl deoxythymidines are recognized by DNA polymerase I as deoxythymidine or deoxycytidine.
Topics: Alkylation; Deoxycytidine; Deoxyguanine Nucleotides; DNA Polymerase I; Escherichia coli; Mutation; Nucleic Acid Conformation; Poly dA-dT; Polymers; Structure-Activity Relationship; Substrate Specificity; Thymidine | 1987 |
Regulation of pyrimidine deoxyribonucleotide metabolism by substrate cycles in dCMP deaminase-deficient V79 hamster cells.
Topics: Animals; Cell Division; Cell Line; Cricetinae; Cytidine Diphosphate; DCMP Deaminase; Deoxycytidine; Deoxycytidine Monophosphate; Deoxycytosine Nucleotides; Deoxyribonucleotides; Deoxyuridine; DNA; Nucleotide Deaminases; Pyrimidines; Thymidine; Thymidine Monophosphate; Thymine Nucleotides; Uridine Diphosphate | 1987 |
Deoxythymidine and deoxycytidine incorporation into DNA in B leukemic cells.
Topics: B-Lymphocytes; Deoxycytidine; Deoxycytidine Kinase; DNA; Humans; Leukemia; Phenotype; Thymidine | 1986 |
Kinetic control of the length of very short homopolymeric additions by terminal deoxynucleotidyltransferase.
Topics: Deoxyadenosines; Deoxycytidine; Deoxyguanosine; DNA Nucleotidylexotransferase; DNA Nucleotidyltransferases; Kinetics; Substrate Specificity; Thymidine | 1986 |
Modulation of induced reversion frequency by nucleotide pool imbalance as a tool for mutant characterization.
Topics: Animals; Cell Line; Cricetinae; Cricetulus; Deoxyadenosines; Deoxycytidine; Fibroblasts; Male; Mutagens; Mutation; Nucleotides; Thymidine | 1987 |
Regulation of thymocyte proliferation and survival by deoxynucleosides. Deoxycytidine produced by thymic accessory cells protects thymocytes from deoxyguanosine toxicity and stimulates their spontaneous proliferation.
Topics: Animals; Antigen-Presenting Cells; Bromodeoxyuridine; Cell Division; Cell Survival; Deoxycytidine; Deoxyguanosine; DNA Replication; Dose-Response Relationship, Immunologic; Fluorescent Antibody Technique; Lymphokines; Mice; Thymidine; Thymus Gland | 1986 |
An improved lymphocyte culture technique: deoxycytidine release of a thymidine block and use of a constant humidity chamber for slide making.
Topics: Cell Division; Cells, Cultured; Chromosomes, Human; Cytogenetics; Deoxycytidine; Humans; Humidity; Lymphocytes; Thymidine | 1987 |
Effect of deoxycytidine on the in vitro response of human leukemia cells to inhibitors of de novo pyrimidine biosynthesis.
Topics: 3-Deazauridine; Amides; Aspartic Acid; Cell Division; Cell Line; Deoxycytidine; Deoxycytidine Kinase; Drug Interactions; Humans; Leukemia, Experimental; Phosphonoacetic Acid; Pyrazoles; Pyrimidines; Ribonucleosides; Ribose; Thymidine | 1987 |
In vitro and in vivo studies of a promising antileukemic thymidine analogue, 5-hydroxymethyl-2' deoxyuridine.
Topics: Animals; Antineoplastic Agents; Blood Platelets; Cell Line; Deoxycytidine; Humans; Leukemia; Leukemia L1210; Thymidine | 1986 |
Enhancement of the anticancer activity of bis(2-chloroethyl)nitrosourea in mice by coadministration of 2'-deoxyuridine, 2'-deoxycytidine, or thymidine.
Topics: Animals; Carmustine; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; Drug Synergism; Leukemia L1210; Melanoma, Experimental; Mice; Ribonucleosides; Thymidine | 1987 |
Search for DNA alterations in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Cerebral Cortex; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Deoxyribonucleosides; DNA; Humans; Middle Aged; Thymidine | 1985 |
On the mechanism of deoxyribonucleoside toxicity in human T-lymphoblastoid cells. Reversal of growth inhibition by addition of cytidine.
Topics: Cell Division; Cell Line; Cytidine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Deoxyribonucleosides; Deoxyribonucleotides; Humans; Leukemia, Lymphoid; Phosphorylation; T-Lymphocytes; Thymidine | 1985 |
Relations between synthesis of deoxyribonucleotides and DNA replication in 3T6 fibroblasts.
Topics: Animals; Aphidicolin; Deoxycytidine; Deoxyribonucleotides; Diterpenes; DNA Replication; Fibroblasts; Hydroxyurea; Mice; Thymidine; Thymidylate Synthase; Thymine Nucleotides | 1985 |
On the regulation of deoxyribonucleotide synthesis.
Topics: Animals; Aphidicolin; Cell Cycle; Cells, Cultured; Cytidine; Deoxycytidine; Deoxyribonucleotides; Diterpenes; DNA Replication; Fibroblasts; Homeostasis; Hydroxyurea; Kinetics; Mice; Thymidine | 1985 |
Reversible permeabilization of lymphocytes destroys the incorporation of deoxythymidine but not of deoxycytidine.
Topics: Cell Membrane Permeability; Child; Child, Preschool; Deoxycytidine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; DNA; DNA Polymerase II; Humans; Lymphocytes; Palatine Tonsil; Phosphorylation; Thymidine; Thymidine Kinase; Thymidine Monophosphate | 1986 |
Salvage of circulating pyrimidine nucleosides by tissues of the mouse.
Topics: Animals; Cytidine; Deoxycytidine; Deoxyuridine; Half-Life; Male; Metabolic Clearance Rate; Mice; Pyrimidine Nucleosides; Thymidine; Tissue Distribution; Uracil; Uridine | 1985 |
Characterization of mouse lymphoma cells with altered nucleoside transport.
Topics: Adenosine; Animals; Biological Transport; Cell Division; Cells, Cultured; Deoxycytidine; Kinetics; Lymphoma; Mice; Nucleosides; Thioinosine; Thymidine | 1985 |
Effects of hydroxyurea and thymidine derivatives on the uptake and metabolism of deoxycytidine and arabinofuranosylcytosine in log phase and contact-inhibited human diploid fibroblasts.
Topics: Arabinofuranosylcytosine Triphosphate; Cells, Cultured; Cytarabine; Deamination; Deoxycytidine; Deoxyuracil Nucleotides; Fibroblasts; Humans; Hydroxyurea; Thymidine; Thymine Nucleotides; Tritium | 1985 |
Centromeric heterochromatin and comparison of G-banding in cattle, goat, and sheep chromosomes (Bovidae).
Topics: Animals; Autoradiography; Cattle; Chromosomes; Deoxycytidine; DNA Replication; Fibroblasts; Goats; Heterochromatin; Karyotyping; Sheep; Staining and Labeling; Thymidine; Tritium | 1974 |
Proliferation of human peripheral lymphocytes. Characteristics of cells once stimulated or re-stimulated by concanavalin A.
Topics: Autoradiography; Bromodeoxyuridine; Carbon Radioisotopes; Cell Division; Centrifugation, Density Gradient; Concanavalin A; Deoxycytidine; DNA; DNA Replication; Dose-Response Relationship, Drug; Floxuridine; Humans; Hybridization, Genetic; Lymphocytes; Mitosis; Thymidine; Time Factors; Tritium | 1973 |
Isotope-dilution analysis of rate-limiting steps and pools affecting the incorporation of thymidine and deoxycytidine into cultured thymus cells.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Cells, Cultured; Culture Media; Cytidine; Deoxycytidine; Deoxyribonucleosides; Floxuridine; Isotope Labeling; Kinetics; Methotrexate; Rats; Thymidine; Thymidylate Synthase; Thymus Gland; Time Factors; Tritium | 1974 |
Effect of arabinosyl-cytosine on the G1-arrested cells which were subsequently induced to divide by medium change.
Topics: Animals; Cell Line; Cells, Cultured; Culture Media; Cytarabine; Deoxycytidine; DNA; Ethidium; Floxuridine; Kidney; Mice; Mice, Inbred Strains; Mitosis; Thymidine; Time Factors; Tritium | 1974 |
An NMR study of the relative interaction abilities of different pyrimidine nucleosides with serotonin.
Topics: Bromodeoxyuridine; Cytidine; Deoxycytidine; Floxuridine; Idoxuridine; Magnetic Resonance Spectroscopy; Pyrimidine Nucleosides; Serotonin; Thymidine; Uridine | 1974 |
Rapid arrest of DNA synthesis by N 6 ,O 2' -dibutyryl cyclic adenosine 3',5'-monophosphate in cultured hepatoma cells.
Topics: Autoradiography; Butyrates; Carcinoma, Hepatocellular; Cells, Cultured; Cyclic AMP; Deoxyadenosines; Deoxycytidine; DNA, Neoplasm; Guanosine; Liver Neoplasms; Mitosis; Neoplasms, Experimental; Thymidine; Thymine Nucleotides; Tritium | 1973 |
Deoxycytidine uptake by isolated membrane vesicles from Escherichia coli K 12.
Topics: Ascorbic Acid; Azides; Biological Transport; Carbon Isotopes; Cell Fractionation; Cell Membrane; Chloromercuribenzoates; Deoxycytidine; Deoxyribonucleosides; Electron Transport; Escherichia coli; Iodoacetates; Lactates; Mutation; NAD; Nucleosides; Organoids; Proline; Succinates; Thymidine; Time Factors; Uridine | 1973 |
Letter: On the source of "minor thymine" in DNA from a Novik off rat hepatoma cell line.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Chromatography, Paper; Cytosine; Deamination; Deoxycytidine; DNA; Liver; Liver Neoplasms; Methotrexate; Neoplasms, Experimental; Rats; Thymidine; Thymine; Tritium | 1973 |
Pyrimidine excretion by cultured fibroblasts: effect of mutational deficiency in pyrimidine salvage enzymes.
Topics: Animals; Carbon Radioisotopes; Cell Line; Cells, Cultured; Chromatography, Thin Layer; Deoxycytidine; Deoxyuridine; Fibroblasts; Mice; Mice, Inbred Strains; Mutation; Phosphotransferases; Pyrimidines; Thymidine; Thymidine Kinase; Uracil | 1974 |
A comparison of the utilization of thymine and thymidine for the synthesis of DNA-thymine in Novikoff hepatoma cells.
Topics: Alkylating Agents; Carcinoma, Hepatocellular; Cells, Cultured; Deoxyadenosines; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; DNA, Neoplasm; Guanosine; Kinetics; Liver Neoplasms; Mesylates; Neoplasms, Experimental; Thymidine; Thymine; Tritium | 1974 |
Cell cycle dependent transcription of SV40 DNA in SV40-transformed cells.
Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Chromatin; Demecolcine; Deoxycytidine; DNA-Directed RNA Polymerases; DNA, Viral; Epithelium; Escherichia coli; Isotope Labeling; Liver; Mitosis; Nucleic Acid Hybridization; Rats; RNA, Viral; Simian virus 40; Thymidine; Time Factors; Transcription, Genetic; Tritium; Uridine | 1974 |
Dosimetry studies on the ethylation of mouse sperm DNA after in vivo exposure to (3H)ethyl metanesulfonate.
Topics: Animals; Arginine; Carbon Radioisotopes; Deoxycytidine; DNA; Dose-Response Relationship, Drug; Ethyl Ethers; Lysine; Male; Mesylates; Mice; Mutagens; Nucleotides; Protamines; Spermatozoa; Testis; Thymidine; Tritium | 1974 |
Programming of events in Epstein-Barr virus-activated cells induced by 5-iododeoxyuridine.
Topics: Antigens, Viral; Autoradiography; Burkitt Lymphoma; Cell Line; Cells, Cultured; Cytarabine; Deoxycytidine; DNA Replication; DNA, Neoplasm; DNA, Viral; Fluorescent Antibody Technique; Herpesvirus 4, Human; Humans; Hydroxyurea; Idoxuridine; Mitosis; Thymidine; Time Factors; Tritium; Viral Proteins; Virus Replication | 1974 |
Induction of both thymidine and deoxycytidine kinase activity by herpes viruses.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cell-Free System; Cricetinae; Cytarabine; Deoxycytidine; Drug Resistance, Microbial; Enzyme Induction; Herpesviridae; Herpesvirus 1, Suid; Horses; Kidney; Mutation; Phosphotransferases; Simplexvirus; Thymidine; Thymidine Kinase; Tritium; Vaccinia virus; Viral Plaque Assay | 1974 |
Alterations leading to increased ribonucleotide reductase in cells selected for resistance to deoxynucleosides.
Topics: Animals; Autoradiography; Cell Line; Cell-Free System; Cells, Cultured; Chromatography, Ion Exchange; Clone Cells; Cytarabine; Deoxyadenosines; Deoxycytidine; Deoxyribonucleosides; Deoxyribonucleotides; DNA; Drug Resistance; Fibroblasts; Guanosine; Mice; Phosphotransferases; Ribonucleotide Reductases; Thymidine; Thymidine Kinase; Tritium | 1974 |
Increased urinary excretion of pyrimidine and nicotinamide derivatives in rats treated with methyl methanesulphonate.
Topics: Animals; Carbon Radioisotopes; Chromatography, Gel; Chromatography, Ion Exchange; Deoxycytidine; Dose-Response Relationship, Drug; Female; Guanine; Hypoxanthines; Mesylates; Niacinamide; Pyrimidines; Radiation; Rats; Spectrophotometry, Ultraviolet; Thymidine; Time Factors | 1974 |
Synthesis of a DNA binding protein in normal and transformed cells.
Topics: Aminopterin; Animals; Carbon Radioisotopes; Cell Line; Cell Transformation, Neoplastic; Chromatography; Deoxycytidine; Depression, Chemical; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Gammaretrovirus; Growth Substances; Hypoxanthines; Leucine; Mice; Mice, Inbred BALB C; Protein Binding; Protein Biosynthesis; Stimulation, Chemical; Thymidine; Time Factors; Tritium | 1974 |
Ribosomal RNA gene amplification by rolling circles.
Topics: Animals; Cyclization; Deoxycytidine; DNA Replication; DNA, Circular; Female; Genes; Microscopy, Electron; Molecular Weight; Ovum; RNA, Ribosomal; Thymidine; Transcription, Genetic; Xenopus | 1974 |
Cytidine 5'-triphosphate synthetase as a target for inhibition by the antitumor agent 3-deazauridine.
Topics: Animals; Cells, Cultured; Cytidine; Cytosine Nucleotides; Deoxycytidine; Deoxyuridine; Enzyme Inhibitors; Leukemia L1210; Ligases; Liver; Mice; Thymidine; Uracil Nucleotides; Uridine | 1974 |
[A comparison between incorporation of the precursors of the A--T and G--C DNA base pairs into the chromosomes of the Chinese hamster].
Topics: Animals; Autoradiography; Chromosomes; Clone Cells; Cricetinae; Deoxycytidine; DNA Replication; Thymidine; Tritium | 1974 |
The patterns of labeling of germinal-center cells with tritiated deoxycytidine.
Topics: Animals; Autoradiography; Deoxycytidine; Deoxyribonucleosides; Isotope Labeling; Lymph Nodes; Lymphocytes; Male; Methods; Rats; T-Lymphocytes; Thymidine; Tritium | 1973 |
Separation of nucleotides, nucleosides and bases of DNA with cation exchange columns.
Topics: Adenine; Animals; Cattle; Chromatography, Ion Exchange; Cytosine; Cytosine Nucleotides; Deoxyadenosines; Deoxycytidine; Deoxyribonucleases; Deoxyribonucleosides; Deoxyribonucleotides; DNA; Evaluation Studies as Topic; Formates; Guanine; Hydrolysis; Methods; Purines; Pyrimidinones; Quaternary Ammonium Compounds; Spectrophotometry, Ultraviolet; Thymidine; Thymine; Thymine Nucleotides; Thymus Gland | 1973 |
Specific increase in pyrimidine deoxynucleoside transport at the time of deoxyribonucleic acid synthesis in 3T3 mouse cells.
Topics: Animals; Biological Transport; Cell Line; Culture Media; Cycloheximide; Cytarabine; Dactinomycin; Deoxyadenosines; Deoxycytidine; Deoxyribonucleosides; DNA; Electrophoresis, Paper; Fibroblasts; Guanosine; Hydroxyurea; Kinetics; Mice; Mitomycins; Mutation; Phosphates; Phosphorus Isotopes; Thymidine; Thymidine Kinase; Time Factors; Tritium | 1973 |
Changes in the deoxyribonucleoside triphosphate pools of mouse 5178Y lymphoma cells following exposure to methotrexate or 5-fluorouracil.
Topics: Adenosine Triphosphate; Animals; Cell Line; Cells, Cultured; Deoxyadenosines; Deoxycytidine; Deoxyribonucleotides; Deoxyuridine; DNA, Neoplasm; Fluorouracil; Guanosine; Leukemia, Experimental; Leukemia, Lymphoid; Methotrexate; Mice; Phosphates; Thymidine; Tritium | 1973 |
Studies on the specificity of an acid deoxyribonuclease from Helix aspersa (Müll.).
Topics: Animals; Cattle; Chromatography, DEAE-Cellulose; Deoxyadenosines; Deoxycytidine; Deoxyribonucleases; Deoxyribonucleotides; DNA; Guanosine; Kinetics; Nucleic Acid Conformation; Oligonucleotides; Phosphates; Snails; Spectrophotometry, Ultraviolet; Spleen; Swine; Thymidine; Thymus Gland | 1973 |
[Interaction of DNA components with chloracetaldehyde].
Topics: Acetaldehyde; Deoxyadenosines; Deoxycytidine; Deoxyribonucleosides; Indicators and Reagents; Spectrophotometry, Ultraviolet; Thymidine | 1973 |
Direct visualization of labeled nucleotides in DNA using electron microscopy and autoradiography.
Topics: Animals; Autoradiography; Cell Line; Deoxyadenosines; Deoxycytidine; Deoxyribonucleosides; DNA; Guanosine; L Cells; Methods; Mice; Microscopy, Electron; Nucleotides; Thymidine; Tritium | 1974 |
Changes in DNA and RNA synthesis and associated enzyme activities after the stimulation of serum-depleted BHK21-C13 cells by the addition of serum.
Topics: Animals; Blood; Carbon Radioisotopes; Carboxy-Lyases; Cell Division; Cell Line; Centrifugation, Density Gradient; Cricetinae; Deoxyadenosines; Deoxycytidine; DNA; DNA Nucleotidyltransferases; DNA Replication; Guanosine; Kidney; Ornithine; Phosphotransferases; RNA; Thymidine; Thymidine Kinase; Time Factors; Tritium; Uridine | 1974 |
A comparative study of the relative ease of thermolytic depurination vs. depyrimidination in 2'-deoxynucleosides.
Topics: Calorimetry; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Deoxyadenosines; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; Dimethyl Sulfoxide; Guanosine; Hot Temperature; Magnetic Resonance Spectroscopy; Molecular Conformation; Purine Nucleosides; Pyrimidine Nucleosides; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Temperature; Thermodynamics; Thymidine | 1974 |
An acute effect of high oxygen tension on the uptake of 3H-deoxycytidine into thymocyte deoxyribonucleic acid.
Topics: Animals; Cells, Cultured; Cytidine; Deoxycytidine; DNA; Oxygen; Rats; T-Lymphocytes; Thymidine; Time Factors; Tritium; Uridine | 1974 |
A mutant of Escherichia coli defective in ribonucleosidediphosphate reductase. 1. Isolation of the mutant as a deoxyuridine auxotroph.
Topics: Alcohol Oxidoreductases; Aminohydrolases; Culture Media; Deoxycytidine; Deoxyribonucleotides; Deoxyuridine; Escherichia coli; Genetics, Microbial; Mutation; Phenotype; Ribonucleotides; Thymidine; Thymidylate Synthase; Thymine Nucleotides; Trimethoprim; Uracil Nucleotides | 1973 |
Further investigations on the specificity of an acid deoxyribonuclease from Helix aspersa (Müll.).
Topics: Animals; Cattle; Deoxyadenosines; Deoxycytidine; Deoxyribonucleases; DNA, Bacterial; Escherichia coli; Guanosine; Haemophilus influenzae; Micrococcus; Nucleic Acid Conformation; Snails; Species Specificity; Thymidine | 1973 |
The specificity of pancreatic deoxyribonuclease.
Topics: Absorption; Animals; Cattle; Deoxyadenosines; Deoxycytidine; Deoxyribonucleases; DNA, Bacterial; Escherichia coli; Guanosine; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Macromolecular Substances; Nucleic Acid Conformation; Oligonucleotides; Pancreas; Solubility; Spectrum Analysis; Thymidine; Thymus Gland | 1973 |
The specificity of Escherichia coli endonuclease I.
Topics: Absorption; Animals; Cattle; Chromatography, DEAE-Cellulose; Deoxyadenosines; Deoxycytidine; DNA, Bacterial; Endonucleases; Escherichia coli; Guanosine; Hydrogen-Ion Concentration; Kinetics; Nucleic Acid Conformation; Oligonucleotides; Solubility; Species Specificity; Spectrum Analysis; Thymidine; Thymus Gland | 1973 |
Nucleoside catabolism in Streptococcus hemolyticus.
Topics: Biodegradation, Environmental; Cell-Free System; Chromatography, Gel; Cytidine; Deoxycytidine; Escherichia coli; Guanosine; Hemolysin Proteins; Nucleosides; Phosphotransferases; Streptococcus; Thymidine; Uridine | 1974 |
Effects of thymidine on deoxyribonucleoside triphosphate pools and deoxyribonucleic acid synthesis in Chinese hamster ovary cells.
Topics: Adenine Nucleotides; Alcohol Oxidoreductases; Allosteric Regulation; Animals; Autoradiography; Cell Division; Cells, Cultured; Cricetinae; Culture Media; Deoxycytidine; Deoxyribonucleotides; DNA; Female; Guanine Nucleotides; Isoleucine; Kinetics; Ovary; Ribonucleotides; Thymidine; Thymine Nucleotides; Tritium | 1973 |
Methylation rapidly reannealing DNA during the cell cycle of Chinese hamster cells.
Topics: Animals; Bromodeoxyuridine; Carbon Isotopes; Cells, Cultured; Computers; Cricetinae; Culture Media; Cytosine; Deoxycytidine; DNA; DNA Replication; Female; Kinetics; Methionine; Methylation; Mitosis; Nucleic Acid Denaturation; Nucleic Acid Renaturation; Nucleotides; Ovary; Thymidine; Thymine; Tritium | 1973 |
Zinc requirement for DNA replication in stimulated human lymphocytes.
Topics: Blood Proteins; Cations, Divalent; Cells, Cultured; Deoxycytidine; DNA Replication; Humans; Lectins; Leucine; Lymphocyte Activation; Lymphocytes; Nickel; Phenanthrolines; RNA; Thymidine; Time Factors; Tritium; Uridine; Zinc | 1973 |
Inhibition of adenovirus multiplication by metabolic inhibitors.
Topics: Adenoviridae; Anti-Bacterial Agents; Antigens, Viral; Antimetabolites; Cell Line; Complement Fixation Tests; Cyclohexanes; Cycloheximide; Cytopathogenic Effect, Viral; Dactinomycin; Deoxycytidine; DNA, Viral; HeLa Cells; Hemagglutination Tests; Humans; Kidney; Mitomycins; Piperidones; Thymidine; Time Factors; Viral Proteins; Virus Replication | 1973 |
Late DNA replication pattern of human chromosomes determined by means of 3H-deoxycytidine.
Topics: Cell Division; Chromosomes; Chromosomes, Human, 1-3; Chromosomes, Human, 16-18; Colchicine; Deoxycytidine; DNA; DNA Replication; Fluorescence; Humans; Isotope Labeling; Male; Quinacrine; Thymidine; Time Factors; Tritium | 1973 |
Replication of repeated DNA in human cells.
Topics: Autoradiography; Base Sequence; Bromodeoxyuridine; Carbon Radioisotopes; Carcinoma; Cell Division; Cell Line; Centrifugation, Density Gradient; Deoxycytidine; DNA; DNA Replication; DNA, Neoplasm; Humans; Mouth Neoplasms; Nucleic Acid Denaturation; Nucleic Acid Renaturation; Thymidine; Time Factors | 1974 |
Role of base composition in the electrophoresis of heat-treated deoxyribonucleic acid from HeLa and mouse cells in composite polyacrylamide gels.
Topics: Adenosine; Animals; Carbon Radioisotopes; Cell Nucleus; Chromatography, Paper; Cytidine; Cytosine Nucleotides; Deoxycytidine; DNA; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Guanine Nucleotides; Guanosine; HeLa Cells; Hot Temperature; Mice; Mice, Inbred C57BL; Nucleic Acid Denaturation; Nucleosides; Nucleotides; Polysaccharides; Thymidine; Tritium | 1974 |
[Distribution of AT and GC pairs of DNA bases along chromosomes 1 and 2 in 2 types of human cells].
Topics: Adult; Base Sequence; Chromosomes, Human, 1-3; Deoxycytidine; DNA; Embryo, Mammalian; Fibroblasts; Humans; In Vitro Techniques; Leukocytes; Male; Thymidine; Tritium | 1974 |
Effects of 5-bromo-2'-deoxyuridine (BUdR) on in vitro colony formation in cultures of mouse bone marrow cells.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Bromodeoxyuridine; Cell Aggregation; Cells, Cultured; Centrifugation, Density Gradient; Chromatography, Gel; Chromatography, Ion Exchange; Culture Media; Deoxycytidine; DNA; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Male; Mice; Mice, Inbred C57BL; Proteinuria; Thymidine; Time Factors; Tritium | 1974 |
Exclusion of exogenous 5-methyl-2'-deoxycytidine from DNA in human leukemic cells. A study with [2(-14)C]- and [methyl-14C]5-methyl-2'-deoxycytidine.
Topics: 5-Methylcytosine; Cell Line; Cytosine; Deoxycytidine; DNA; Humans; Leucine; Leukemia, Lymphoid; RNA; Thymidine; Uridine | 1983 |
Design of nucleoside, oligonucleotide and polynucleotide analogues as antiviral agents.
Topics: Adenosine; Antiviral Agents; Deoxycytidine; DNA-Directed DNA Polymerase; DNA-Directed RNA Polymerases; Nucleosides; Oligonucleotides; Polynucleotides; RNA-Directed DNA Polymerase; Structure-Activity Relationship; Thymidine; Viruses | 1982 |
The problem of host DNA synthesis in murine cytomegalovirus-infected cells.
Topics: Animals; Cell Line; Cell Nucleus; Cytomegalovirus; Cytoplasm; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; DNA; Mice; Phosphates; Thymidine; Uridine | 1980 |
2'-fluoro-5-iodo-aracytosine, a potent and selective anti-herpesvirus agent.
Topics: Antiviral Agents; Cytarabine; Deoxycytidine; Herpesvirus 3, Human; Microbial Sensitivity Tests; Simplexvirus; Thymidine; Thymidine Kinase | 1980 |
Inhibitors of nuclear ADP-ribosyl transferase retard DNA repair after N-methyl-N-nitroso-urea. Further evidence for the involvement of (ADP-ribose)n in DNA repair.
Topics: Adenosine Diphosphate Ribose; Animals; Cell Division; Centrifugation, Density Gradient; Deoxycytidine; DNA Repair; Leukemia L1210; Methylnitrosourea; Mice; Niacinamide; Nitrosourea Compounds; Nucleoside Diphosphate Sugars; Nucleotidyltransferases; Poly(ADP-ribose) Polymerases; Thymidine | 1981 |
Conformational stability of alternating d (CG) oligomers in high salt solution.
Topics: Chlorides; Circular Dichroism; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Drug Stability; Lithium; Lithium Chloride; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Oligonucleotides; Osmolar Concentration; Sodium Chloride; Thymidine | 1981 |
G1-phase arrest of cultured human leukemic T-cells induced by deoxyadenosine.
Topics: Adenosine Kinase; B-Lymphocytes; Cell Cycle; Cell Transformation, Viral; Cells, Cultured; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Deoxyribonucleosides; Flow Cytometry; Herpesvirus 4, Human; Humans; Hydroxyurea; Leukemia, Lymphoid; T-Lymphocytes; Thymidine | 1981 |
In vitro alkylation of calf thymus DNA by acrylonitrile. Isolation of cyanoethyl-adducts of guanine and thymine and carboxyethyl-adducts of adenine and cytosine.
Topics: Acrylonitrile; Alkylating Agents; Animals; Cattle; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; DNA; Guanine; Hydrogen-Ion Concentration; Inosine; Nitriles; Propiolactone; Thymidine; Thymus Gland | 1984 |
Effects of conditioned medium on nucleoside uptake, cell cycle progression and apparent DNA repair.
Topics: Animals; Arvicolinae; Cell Cycle; Cell Line; Cells, Cultured; Cricetinae; Culture Media; Cytarabine; Deoxycytidine; DNA Repair; Fibroblasts; Humans; Mice; Nucleosides; Thymidine; Time Factors | 1983 |
The use of capillary gas chromatography-mass spectrometry for identification of radiation-induced DNA base damage and DNA base-amino acid cross-links.
Topics: Amino Acids; Base Composition; Chemical Phenomena; Chemistry; Chromatography, Gas; Cytosine; Deoxycytidine; DNA; Formates; Gamma Rays; Gas Chromatography-Mass Spectrometry; Hydrochloric Acid; Hydrolysis; Thymidine; Thymidine Monophosphate; Thymine; Tyrosine | 1984 |
Undermethylation of DNA in mononucleosomes solubilized by micrococcal nuclease digestion of HeLa cell nuclei.
Topics: Cell Nucleus; Centrifugation, Density Gradient; Chromatin; Deoxycytidine; Deoxyribonucleases; DNA; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Hydrolysis; Methylation; Micrococcal Nuclease; Nucleosomes; Sucrose; Thymidine | 1984 |
Epigenetic effects of the methylating agent 5-(3-methyl-1-triazeno) imidazole-4-carboxamide in human melanoma cells.
Topics: Alkylating Agents; Antineoplastic Agents; Cell Line; Dacarbazine; Deoxycytidine; Deoxyguanosine; Genes; Humans; Melanoma; Theophylline; Thymidine | 1984 |
Dynamics of pyrimidine deoxynucleoside triphosphate pools in relationship to DNA synthesis in 3T6 mouse fibroblasts.
Topics: Animals; Cytidine; Deoxycytidine; DNA Replication; Fibroblasts; Mice; Pyrimidine Nucleosides; Thymidine; Thymine Nucleotides | 1983 |
The study of human myeloid differentiation using bromodeoxyuridine (BrdU).
Topics: Bromodeoxyuridine; Cell Differentiation; Cell Line; Deoxycytidine; DNA; Granulocytes; Humans; Idoxuridine; Kinetics; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Macrophages; Thymidine; Thymidine Kinase | 1983 |
Modulation of deoxycytidine metabolism in vivo with high-dose thymidine in mice.
Topics: Animals; Bone Marrow; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Deoxycytidine; DNA, Neoplasm; Duodenum; Half-Life; Kinetics; Leukemia L1210; Mice; Mice, Inbred Strains; Spleen; Thymidine | 1983 |
Dipyridamole inhibits reversion by thymidine of methotrexate effect and increases drug uptake in Sarcoma 180 cells.
Topics: Animals; Biological Transport; Deoxycytidine; Deoxyuridine; Dipyridamole; DNA Replication; Drug Antagonism; Kinetics; Methotrexate; Mice; Sarcoma 180; Thymidine; Thymine Nucleotides | 1984 |
Quantitative study of deoxycytidine incorporation in large and small lymphocytes of the mouse.
Topics: Animals; Autoradiography; Deoxycytidine; DNA; Kinetics; Lymph Nodes; Lymphocytes; Male; Mice; Mice, Inbred ICR; T-Lymphocytes; Thymidine; Thymidine Monophosphate | 1983 |
Improved therapeutic index with high-dose methotrexate: comparison of thymidine-purine rescue with citrovorum factor rescue in mice.
Topics: Animals; Brain Neoplasms; Deoxycytidine; DNA Replication; Dose-Response Relationship, Drug; Hypoxanthine; Hypoxanthines; Inosine; Leucovorin; Leukemia L1210; Methotrexate; Mice; Thymidine; Thymine | 1984 |
Factors modifying the synergistic toxicity of deoxycytidine in combination with thymidine plus 5-fluorouracil in HeLa cells.
Topics: Cell Survival; Culture Media; Deoxycytidine; Dose-Response Relationship, Drug; Drug Synergism; Fluorouracil; HeLa Cells; Humans; Hypoxanthine; Hypoxanthines; Interphase; Kinetics; Mitosis; Thymidine | 1983 |
Modulation of metabolism of cytosine arabinoside in L cells by antibody and complement.
Topics: Animals; Antibodies; Cell Line; Complement System Proteins; Cytarabine; Deoxycytidine; Deoxycytidine Kinase; L Cells; Mice; Nucleosides; Thymidine | 1983 |
Induction of sister-chromatid exchanges (SCEs) by thymidine and the potentiation of mutagen-induced SCEs in Chinese hamster ovary cells.
Topics: Animals; Cells, Cultured; Cricetinae; Cricetulus; Crossing Over, Genetic; Deoxycytidine; Dose-Response Relationship, Drug; Drug Synergism; Female; Methylnitronitrosoguanidine; Ovary; Sister Chromatid Exchange; Thymidine | 1983 |
Thymidine as a kinetic and biochemical modulator of 1-beta-D-arabinofuranosylcytosine in human acute nonlymphocytic leukemia.
Topics: Acute Disease; Adult; Cytarabine; Deoxycytidine; Female; Humans; Interphase; Kinetics; Leukemia; Male; Middle Aged; Phosphorylation; Thymidine | 1984 |
Strategies for the measurement of the inhibitory effects of thymidine analogs on the activity of thymidylate synthase in intact murine leukemia L1210 cells.
Topics: Animals; Deoxycytidine; Deoxyuridine; DNA; Leukemia L1210; Methyltransferases; Mice; Thymidine; Thymidylate Synthase | 1984 |
Induction of sister chromatid exchange by 3-aminobenzamide is independent of bromodeoxyuridine.
Topics: Animals; Benzamides; Bromodeoxyuridine; Cell Cycle; Cell Line; Cricetinae; Cricetulus; Crossing Over, Genetic; Deoxycytidine; DNA Replication; Female; Kinetics; Ovary; Sister Chromatid Exchange; Thymidine | 1984 |
Synthesis and biological properties of some cyclic phosphotriesters derived from 2'-deoxy-5-fluorouridine.
Topics: Animals; Antimetabolites, Antineoplastic; Bromodeoxyuridine; Deoxycytidine; Deoxyuridine; Drug Resistance; Indicators and Reagents; Leukemia L1210; Mice; Organophosphorus Compounds; Structure-Activity Relationship; Thymidine; Thymidine Monophosphate | 1984 |
Inhibition of thymidylate synthase by hydroxyurea in rapidly proliferating P815 mastocytoma cells.
Topics: Animals; Deoxycytidine; Deoxyuridine; DNA, Neoplasm; Hydroxyurea; Mast-Cell Sarcoma; Methyltransferases; Mice; Thymidine; Thymidylate Synthase | 1982 |
Effects of 5-bromodeoxyuridine on in vitro development of mouse embryos in the early somitic stage.
Topics: Animals; Bromodeoxyuridine; Deoxycytidine; Dose-Response Relationship, Drug; Embryo, Mammalian; Growth; Mice; Organ Culture Techniques; Thymidine; Time Factors | 1983 |
Labelling of the thymidine and deoxycytidine bases of DNA by [2-14C]deoxycytidine in cultured L1210 cells.
Topics: 3-Deazauridine; Animals; Carbon Radioisotopes; Cytarabine; Cytidine; Deoxycytidine; DNA; Leukemia L1210; Mice; Tetrahydrouridine; Thymidine | 1983 |
Growth inhibition by thymidine of leukemic HL-60 and normal human myeloid progenitor cells.
Topics: Cell Differentiation; Cell Line; Clone Cells; Colony-Forming Units Assay; Deoxycytidine; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid; Thymidine; Time Factors | 1981 |
DNA synthesis in thymic-acute lymphoblastic leukaemia.
Topics: Bone Marrow; Deoxycytidine; Deoxyribonucleosides; DNA; DNA, Neoplasm; Humans; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Myasthenia Gravis; Thymidine; Thymus Gland | 1981 |
Comparison of in vitro and in vivo effects of thymidine on L1210 leukemia in mice.
Topics: Animals; Cell Survival; Chromatography, High Pressure Liquid; Clone Cells; Deoxycytidine; Dose-Response Relationship, Drug; Leukemia L1210; Mice; Mice, Inbred BALB C; Spleen; Thymidine; Time Factors | 1982 |
Isotope-dilution analysis of the effects of deoxyguanosine and deoxyadenosine on the incorporation of thymidine and deoxycytidine by hydroxyurea-treated thymus cells.
Topics: Animals; Cells, Cultured; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Hydroxyurea; Rats; Thymidine; Thymus Gland; Tritium | 1980 |
Induction of chromosome shattering and micronuclei by ultraviolet light and caffeine. I. Temporal relationship and antagonistic effects of the four deoxyribonucleosides.
Topics: Animals; Caffeine; Cell Line; Cell Nucleus; Chromosomes; Cricetinae; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Deoxyribonucleosides; Mitosis; Thymidine; Ultraviolet Rays | 1980 |
Purine nucleoside analogues inhibit the repair of radiation-induced potentially lethal damage in mammalian cells in culture.
Topics: Animals; Cells, Cultured; Cricetinae; Cricetulus; Deoxycytidine; Deoxyguanosine; Deoxyuridine; Dideoxynucleosides; DNA Repair; Dose-Response Relationship, Drug; Purine Nucleosides; Thymidine; Vidarabine | 1982 |
Mechanism of deoxycytidine rescue of thymidine toxicity in human T-leukemic lymphocytes.
Topics: Cell Division; Cell Line; Deoxycytidine; Deoxyribonucleotides; DNA Replication; Humans; Leukemia; Lymphocytes; Ribonucleotide Reductases; Thymidine | 1980 |
Interaction of an Escherichia coli mutator gene with a deoxyribonucleotide effector.
Topics: Culture Media; Deoxycytidine; Deoxyuridine; Escherichia coli; Genes; Mutation; Thymidine | 1980 |
Somatic mutation and neoplastic transformation induced by [methyl-3H]thymidine.
Topics: Animals; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cricetinae; Deoxycytidine; DNA; Mesocricetus; Mutation; Phenotype; Thymidine; Tritium | 1982 |
The effects of methylated thymidines upon cultures of V79 cells and the mechanism of incorporation of O4-methylthymidine into their DNA.
Topics: Animals; Cell Count; Cell Line; Cell Survival; Cricetinae; Cricetulus; Deoxycytidine; DNA; Drug Interactions; Methotrexate; Mutation; Thymidine; Time Factors | 1982 |
Psoralen-deoxyribonucleic acid photoreaction. Characterization of the monoaddition products from 8-methoxypsoralen and 4,5'8-trimethylpsoralen.
Topics: Chromatography, High Pressure Liquid; Deoxycytidine; DNA; Furocoumarins; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methoxsalen; Photochemistry; Thymidine; Trioxsalen | 1982 |
Biochemical effects of 2'-fluoro-5-methyl-1-beta-D-arabinofuranosyluracil and 2'-fluoro-5-iodo-1-beta-D-arabinofuranosylcytosine in mouse leukemic cells sensitive and resistant to 1-beta-D-arabinofuranosylcytosine.
Topics: Animals; Arabinofuranosyluracil; Cell Survival; Cytarabine; Deoxycytidine; DNA Replication; Kinetics; Leukemia L1210; Leukemia, Experimental; Mice; Thymidine; Uridine | 1982 |
Patterns of in vitro labeling of bone marrow lymphocytes and antibody-producing cells with tritiated thymidine and deoxycytidine: difference between the two cell types.
Topics: Animals; Antibody-Producing Cells; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Deoxycytidine; DNA; Guinea Pigs; Lymphocytes; Male; Mice; Thymidine; Tritium | 1980 |
Cytotoxic and cytokinetic effects of thymidine, 5-fluorouracil, and deoxycytidine on HeLa cells in culture.
Topics: Cell Division; Cell Survival; Colony-Forming Units Assay; Deoxycytidine; DNA; Dose-Response Relationship, Drug; Fluorouracil; HeLa Cells; Humans; Thymidine; Time Factors | 1981 |
Effects of metabolic inhibitors on cel lethality and mutation induction in Chinese hamster cells. II. The effect of posttreatment with non-toxic concentrations of thymidine.
Topics: Animals; Azaguanine; Cell Line; Cricetinae; Cricetulus; Deoxycytidine; Ethylnitrosourea; Lung; Methylnitrosourea; Mutation; Thioguanine; Thymidine; Ultraviolet Rays | 1981 |
Pathogenesis of bromodeoxyuridine-induced polydactyly.
Topics: Abnormalities, Drug-Induced; Animals; Bromodeoxyuridine; Cell Survival; Deoxycytidine; DNA; Dose-Response Relationship, Drug; Female; Hindlimb; Pregnancy; Rats; Thymidine; Toes | 1981 |
Tritiated thymidine and deoxycytidine suicide of mouse hemopoietic colony forming cells (CFC).
Topics: Animals; Cell Survival; Cells, Cultured; Deoxycytidine; Female; Hematopoietic Stem Cells; Mice; Mice, Inbred Strains; Nucleosides; Pyrimidines; Thymidine; Tritium | 1981 |
Hydralazine reactions.
Topics: Deoxycytidine; Humans; Hydralazine; Thymidine | 1981 |
Radioimmunoassays of plasma thymidine, uridine, deoxyuridine, and cytidine/deoxycytidine.
Topics: Animals; Cytidine; Deoxycytidine; Deoxyuridine; Immune Sera; Radioimmunoassay; Thymidine; Uridine | 1981 |
[3H] thymidine incorporation in bovine lymphocytes treated with the tumor promoter, 12-O-tetradecanoyl phorbol-13-acetate.
Topics: Animals; Cattle; Cells, Cultured; Deoxycytidine; DNA; Lymph Nodes; Lymphocytes; Phorbols; Phytohemagglutinins; Tetradecanoylphorbol Acetate; Thymidine; Tritium | 1981 |
Effect of thymidine on the toxicity, antitumor activity, and metabolism of 1-beta-D-arabinofuranosylcytosine in rats bearing a chemically induced colon carcinoma.
Topics: Animals; Arabinofuranosylcytosine Triphosphate; Biotransformation; Colonic Neoplasms; Cytarabine; Deoxycytidine; Drug Interactions; Drug Therapy, Combination; Female; Neoplasms, Experimental; Rats; Thymidine; Tissue Distribution | 1980 |
Individual changes of DNA catabolite excretion in the course of antitumor therapy of Hodgkin's disease.
Topics: Cyclophosphamide; Deoxycytidine; Deoxyuridine; Hodgkin Disease; Humans; Prednisone; Procarbazine; Thymidine | 1980 |
Enhancement of 1-beta-D-arabinofuranosylcytosine accumulation within L1210 cells and increased cytotoxicity following thymidine exposure.
Topics: Animals; Arabinofuranosylcytosine Triphosphate; Cytarabine; Deoxycytidine; Deoxyribonucleotides; DNA, Neoplasm; Leukemia L1210; Mice; RNA, Neoplasm; Thymidine; Time Factors | 1980 |
Different labelling patterns in mouse lymphoid tissues with [3H]deoxycytidine and [3H]thymidine.
Topics: Animals; Autoradiography; Cell Division; Deoxycytidine; DNA; Lymph Nodes; Lymphocytes; Male; Mice; Mice, Inbred ICR; Thymidine; Thymus Gland; Tritium | 1980 |
5-Bromodeoxycytidine in the study of sister chromatid exchanges in human lymphocytes.
Topics: Bromodeoxycytidine; Chromatids; Crossing Over, Genetic; Cytidine; Deoxycytidine; DNA; Humans; Lymphocytes; Sister Chromatid Exchange; Thymidine | 1980 |
Identification of cytidine deaminase as inhibitor of granulocyte-macrophage colony formation.
Topics: Animals; Azacitidine; Bone Marrow Cells; Cell Division; Cytarabine; Cytidine Deaminase; Deoxycytidine; Deoxyuridine; DNA; Female; Granulocytes; Hematopoietic Stem Cells; Macrophages; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Thymidine | 1994 |
Nucleoside transport and metabolism in lymphocytes, polymorphonuclear cells and cerebral synaptosomes.
Topics: Adenosine; Animals; Biological Transport; Cerebral Cortex; Child; Deoxycytidine; Dilazep; Dipyridamole; DNA; Humans; Kinetics; Lymphocytes; Neutrophils; Nucleosides; Palatine Tonsil; Papaverine; Rats; Synaptosomes; Thioinosine; Thymidine; Uridine | 1994 |
Formation of cyclobutane dimers and (6-4) photoproducts upon far-UV photolysis of 5-methylcytosine-containing dinucleotide monophosphates.
Topics: 5-Methylcytosine; Cytosine; Deoxycytidine; Dinucleoside Phosphates; Magnetic Resonance Spectroscopy; Photochemistry; Pyrimidine Dimers; Thymidine; Ultraviolet Rays | 1994 |
A novel effect of the new antileukemic drug, 2-chloro-2'-deoxyadenosine, in human lymphocytes.
Topics: Cells, Cultured; Child; Child, Preschool; Cladribine; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyuracil Nucleotides; DNA; Humans; Kinetics; Lymphocytes; Palatine Tonsil; Thymidine; Thymine Nucleotides; Time Factors; Tritium | 1994 |
8-Hydroxyguanine is not produced by permanganate oxidation of DNA.
Topics: Deoxycytidine; Deoxyguanosine; DNA Damage; DNA, Single-Stranded; DNA, Viral; Guanine; Hydrogen-Ion Concentration; Kinetics; Oxidation-Reduction; Potassium Permanganate; Thymidine | 1994 |
Effects of mutational loss of nucleoside kinases on deoxyadenosine 5'-phosphate/deoxyadenosine substrate cycle in cultured CEM and V79 cells.
Topics: Adamantane; Adenine; Adenosine; Adenosine Kinase; Animals; Cell Division; Cell Line; Cricetinae; Deoxyadenosines; Deoxycytidine; Deoxycytidine Kinase; Deoxyribonucleotides; DNA; Fibroblasts; Humans; Hypoxanthine; Hypoxanthines; Kinetics; Lymphocytes; Thymidine; Time Factors; Tritium | 1994 |
Restriction and enhancement of human immunodeficiency virus type 1 replication by modulation of intracellular deoxynucleoside triphosphate pools.
Topics: CD4 Antigens; Cells, Cultured; Deoxyadenine Nucleotides; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; HIV-1; Humans; Proviruses; Thymidine; Thymine Nucleotides; Transcription, Genetic; Virus Replication | 1994 |
Deoxyribocytidine is salvaged not only into DNA but also into phospholipid precursors. IV. Exogenous deoxyribocytidine can be used with the same efficacy as (ribo)cytidine for lipid activation.
Topics: Cells, Cultured; Cytidine; Deoxycytidine; DNA; Humans; Kinetics; Lymphocytes; Models, Biological; Palatine Tonsil; Phospholipids; Thymidine; Tritium | 1993 |
Deoxyribonucleoside triphosphate pools and thymidine chemosensitization in human T-cell leukemia.
Topics: Carboplatin; Deoxyadenosines; Deoxycytidine; Deoxyribonucleotides; Humans; Leukemia, T-Cell; Thymidine; Tumor Cells, Cultured | 1993 |
The salvage of deoxycytidine into dCDP-diacylglycerol by macrophages and lymphocytes.
Topics: Animals; Child; Child, Preschool; Chlorpromazine; Cytidine Diphosphate Diglycerides; Deoxycytidine; DNA; Humans; Lymphocytes; Macrophages; Mice; Palatine Tonsil; Peritoneal Cavity; Pyrimidines; Thymidine | 1993 |
Deoxyadenosine blockade of G0 to G1 transition in lymphocytes: possible involvement of protein kinases.
Topics: Alkaloids; Animals; Blotting, Western; Calcium; Cell Death; Cells, Cultured; Concanavalin A; Deoxyadenosines; Deoxycytidine; Drug Synergism; Flow Cytometry; G1 Phase; Lymphocyte Activation; Lymphocytes; Mice; Mice, Inbred Strains; Protein Kinases; Resting Phase, Cell Cycle; Spleen; Staurosporine; Thymidine | 1996 |
Reaction of epichlorohydrin with 2'-deoxynucleosides: characterization of adducts.
Topics: Chromatography, High Pressure Liquid; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Deoxyribonucleosides; Deoxyuridine; DNA Adducts; Environmental Pollution; Epichlorohydrin; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Occupational Exposure; Thymidine | 1996 |
In vitro sensitivity of macropodid herpesvirus 2 to selected anti-herpetic compounds.
Topics: Acyclovir; Animals; Antiviral Agents; Arabinonucleosides; Bromodeoxycytidine; Bromodeoxyuridine; Cell Line; Cytarabine; Deoxycytidine; Herpesviridae; Herpesviridae Infections; Idoxuridine; Macropodidae; Microbial Sensitivity Tests; Neutralization Tests; Thymidine; Trifluridine; Vidarabine | 1996 |
Effects of fludarabine and gemcitabine on human acute myeloid leukemia cell line HL 60: direct comparison of cytotoxicity and cellular Ara-C uptake enhancement.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Cell Division; Cell Survival; Cytarabine; Deoxycytidine; Drug Interactions; Gemcitabine; HL-60 Cells; Humans; Thymidine; Vidarabine | 1996 |
NMR solution structure of an oligodeoxynucleotide duplex containing the exocyclic lesion 3,N4-etheno-2'-deoxycytidine opposite thymidine: comparison with the duplex containing deoxyadenosine opposite the adduct.
Topics: Base Composition; Base Sequence; Deoxyadenosines; Deoxycytidine; DNA Adducts; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Protons; Solutions; Thermodynamics; Thymidine | 1996 |
Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2.
Topics: Amino Acid Sequence; Base Sequence; Chromosome Mapping; Cloning, Molecular; Deoxycytidine; Deoxycytidine Kinase; Deoxyuridine; DNA, Complementary; Humans; Molecular Sequence Data; Phosphotransferases (Alcohol Group Acceptor); Polymerase Chain Reaction; Sequence Alignment; Thymidine; Thymidine Kinase | 1997 |
Thymidine in the micromolar range promotes rejoining of UVC-induced DNA strand breaks and prevents azidothymidine from inhibiting the rejoining in quiescent human lymphocytes.
Topics: Adult; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; DNA Damage; DNA Repair; Humans; Lymphocytes; Methyl Methanesulfonate; Middle Aged; Reproducibility of Results; Thymidine; Ultraviolet Rays; Zidovudine | 1997 |
New nucleoside-5'-alkylphosphonophosphates and related compounds containing 2'-deoxycytidine, thymidine and adenosine as nucleoside component. Syntheses and their effects on tumor cell growth in vitro.
Topics: Adenosine; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Division; Chromatography, Thin Layer; Deoxycytidine; Female; Humans; Mass Spectrometry; Molecular Structure; Nucleotides; Organophosphorus Compounds; Phospholipids; Thymidine; Tumor Cells, Cultured | 1997 |
The structures and relative stabilities of d(G x G) reverse Hoogsteen, d(G x T) reverse wobble, and d(G x C) reverse Watson-Crick base-pairs in DNA crystals.
Topics: Computer Simulation; Crystallography, X-Ray; Deoxycytidine; Deoxyguanosine; DNA; Hydrogen Bonding; Models, Chemical; Models, Molecular; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Thymidine | 1997 |
Estrogen-nucleic acid adducts: reaction of 3,4-estrone-o-quinone radical anion with deoxyribonucleosides.
Topics: Anions; Carcinogens; Chromatography, High Pressure Liquid; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Deoxyribonucleosides; Estrenes; Free Radicals; Magnetic Resonance Spectroscopy; Thymidine | 1997 |
PET 2-fluoro-2-deoxyglucose uptake in rat prostate adenocarcinoma during chemotherapy with gemcitabine.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Biological Transport; Deoxycytidine; Deoxyglucose; DNA, Neoplasm; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Gemcitabine; Glucose; Male; Neoplasm Transplantation; Prostatic Neoplasms; Radiopharmaceuticals; Rats; Ribonucleotide Reductases; Thymidine; Tomography, Emission-Computed; Tritium; Tumor Cells, Cultured | 1997 |
Nucleoside-mediated mitigation of 5-fluorouracil-induced toxicity in synchronized murine erythroleukemic cells.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Cycle; Deoxycytidine; Deoxyguanine Nucleotides; Embryo, Mammalian; Female; Flow Cytometry; Fluorouracil; Leukemia, Erythroblastic, Acute; Mice; Pregnancy; Rats; Rats, Sprague-Dawley; Thymidine; Thymine Nucleotides | 1997 |
Relaxed enantioselectivity of human mitochondrial thymidine kinase and chemotherapeutic uses of L-nucleoside analogues.
Topics: Binding, Competitive; Bromodeoxyuridine; Cyclopentanes; Cytosol; Deoxycytidine; Deoxycytidine Kinase; Deoxyuridine; HeLa Cells; Humans; Mitochondria; Phosphorylation; Stereoisomerism; Substrate Specificity; Thymidine; Thymidine Kinase | 1997 |
Mechanism of degradation of 2'-deoxycytidine by formamide: implications for chemical DNA sequencing procedures.
Topics: Bromodeoxycytidine; Deoxycytidine; Formamides; Sensitivity and Specificity; Sequence Analysis, DNA; Thymidine | 1997 |
Four deoxynucleoside kinase activities from Drosophila melanogaster are contained within a single monomeric enzyme, a new multifunctional deoxynucleoside kinase.
Topics: Animals; Binding, Competitive; Cells, Cultured; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Drosophila melanogaster; Kinetics; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Substrate Specificity; Thymidine | 1998 |
UV resonance Raman spectroscopy of DNA and protein constituents of viruses: assignments and cross sections for excitations at 257, 244, 238, and 229 nm.
Topics: Deoxyadenosines; Deoxycytidine; Deoxyguanosine; DNA Viruses; DNA, Viral; Phenylalanine; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Sulfates; Thymidine; Tryptophan; Tyrosine; Viral Proteins | 1998 |
Selective multiple labeling strategy to obtain accurate NMR parameters for nucleic acids. Conformational analysis around the glycosidic bond.
Topics: Carbon Isotopes; Deoxycytidine; Glycosides; Isotope Labeling; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Pyrimidine Nucleosides; Reproducibility of Results; Thymidine | 1997 |
Effect of deoxynucleosides on the repair of UV induced DNA breaks.
Topics: Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Deoxyribonucleosides; DNA Damage; DNA Repair; Humans; In Vitro Techniques; Kinetics; Lymphocytes; Thymidine; Ultraviolet Rays | 1998 |
Activation of deoxycytidine kinase during inhibition of DNA synthesis in human lymphocytes.
Topics: Cladribine; DCMP Deaminase; Deoxycytidine; Deoxycytidine Kinase; DNA; DNA Replication; Enzyme Activation; Humans; In Vitro Techniques; Kinetics; Lymphocytes; Palatine Tonsil; Thymidine | 1998 |
Similar changes were induced by Cladribine and by gemcitabine, in the deoxypyrimidine salvage, during short-term treatments.
Topics: Antimetabolites, Antineoplastic; Cell Line; Cladribine; DCMP Deaminase; Deoxycytidine; Deoxycytidine Kinase; Deoxyuracil Nucleotides; Enzyme Inhibitors; Fluorodeoxyuridylate; Gemcitabine; Humans; In Vitro Techniques; Kinetics; Lymphocytes; Palatine Tonsil; Thymidine; Thymidine Kinase | 1998 |
DNA modifications by the mutagen glyoxal: adduction to G and C, deamination of C and GC and GA cross-linking.
Topics: Cytosine; Deamination; Deoxycytidine; Deoxyguanosine; Deoxyuridine; DNA Adducts; Glyoxal; Guanine; Single-Strand Specific DNA and RNA Endonucleases; Thymidine | 1998 |
An Escherichia coli system expressing human deoxyribonucleoside salvage enzymes for evaluation of potential antiproliferative nucleoside analogs.
Topics: Antineoplastic Agents; Antiviral Agents; Deoxycytidine; Deoxycytidine Kinase; Escherichia coli; Humans; Nucleosides; Thymidine; Thymidine Kinase | 1998 |
Inhibition of [3H]thymidine incorporation into DNA of rat regenerating liver by 2',2'-difluorodeoxycytidine coupled to lactosaminated poly-L-lysine.
Topics: Amino Sugars; Animals; Antimetabolites, Antineoplastic; Asialoglycoprotein Receptor; Cell Line; Deoxycytidine; DNA; DNA, Neoplasm; Gemcitabine; Humans; Liver Regeneration; Male; Models, Biological; Nucleic Acid Synthesis Inhibitors; Polylysine; Rats; Rats, Wistar; Receptors, Cell Surface; Thymidine; Tritium; Tumor Cells, Cultured | 1999 |
Differential ganciclovir-mediated cell killing by glutamine 125 mutants of herpes simplex virus type 1 thymidine kinase.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Caspases; Cell Cycle; Cell Line; Deoxycytidine; Ganciclovir; Genetic Therapy; Glutamine; Herpesvirus 1, Human; Mice; Mutation; Thymidine; Thymidine Kinase | 1999 |
The multifunctional deoxynucleoside kinase of insect cells is a target for the development of new insecticides.
Topics: Animals; Bromodeoxyuridine; Cell Cycle; Cell Division; Deoxycytidine; Drosophila melanogaster; Insecticides; Mitochondria; Phosphotransferases (Alcohol Group Acceptor); Thymidine; Thymidine Kinase; Thymidylate Synthase; Tritium | 2000 |
Role of p53 in cellular response to anticancer nucleoside analog-induced DNA damage.
Topics: Antineoplastic Agents; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Deoxycytidine; DNA Damage; Gemcitabine; Thymidine; Tumor Suppressor Protein p53; Vidarabine | 2000 |
Effects of X-irradiation on DNA precursor metabolism and deoxyribonucleoside triphosphate pools in Chinese hamster cells.
Topics: Animals; CHO Cells; Cricetinae; Cytidine; Deoxyadenine Nucleotides; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA Damage; DNA Repair; DNA Replication; Dose-Response Relationship, Radiation; Intracellular Fluid; RNA; S Phase; Thymidine; Thymine Nucleotides | 1974 |
Retroviral transduction of cancer cell lines with the gene encoding Drosophila melanogaster multisubstrate deoxyribonucleoside kinase.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antiviral Agents; Arabinonucleosides; Bromodeoxyuridine; Catalysis; Cell Division; Cell Nucleus; Cladribine; Cytarabine; Deoxycytidine; Drosophila melanogaster; Gemcitabine; Humans; Inhibitory Concentration 50; Kinetics; Osteosarcoma; Pancreatic Neoplasms; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Promoter Regions, Genetic; Retroviridae; Substrate Specificity; Thymidine; Thymidine Kinase; Transduction, Genetic; Tumor Cells, Cultured | 2000 |
Cloning and characterization of full-length mouse thymidine kinase 2: the N-terminal sequence directs import of the precursor protein into mitochondria.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Chromatography, Affinity; Chromatography, Gel; Cloning, Molecular; Deoxycytidine; Deoxyuridine; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Library; Humans; Kinetics; Mice; Mitochondria; Mitochondria, Liver; Molecular Sequence Data; Phosphorylation; Protein Biosynthesis; Rats; Recombinant Proteins; RNA, Messenger; Sequence Analysis, Protein; Thymidine; Thymidine Kinase; Tissue Distribution | 2000 |
Antiviral L-nucleosides specific for hepatitis B virus infection.
Topics: Animals; Anti-HIV Agents; Antiviral Agents; Bone Marrow Cells; Cell Line; Deoxyadenosines; Deoxycytidine; DNA-Directed DNA Polymerase; DNA, Viral; Female; Hepatitis B; Hepatitis B virus; HIV-1; Humans; Male; Marmota; Nucleosides; Stem Cells; Thymidine; Virus Replication | 2001 |
Apoptosis and changes in glucose transport early after treatment of Morris hepatoma with gemcitabine.
Topics: 3-O-Methylglucose; Animals; Antimetabolites, Antineoplastic; Apoptosis; Deoxycytidine; DNA, Neoplasm; Fluorodeoxyglucose F18; Gemcitabine; Glucose; Immunohistochemistry; Liver Neoplasms, Experimental; Neoplasm Transplantation; Phosphorylation; Radiopharmaceuticals; Rats; Rats, Inbred Strains; Thymidine; Tomography, Emission-Computed; Tumor Cells, Cultured | 2001 |
Characterization of nucleoside and DNA adducts formed by S-(1-acetoxymethyl)glutathione and implications for dihalomethane-glutathione conjugates.
Topics: Deoxyadenosines; Deoxycytidine; Deoxyguanosine; DNA; DNA Adducts; Endodeoxyribonucleases; Exonucleases; Glutathione; Methylene Chloride; Nucleosides; Thymidine | 2001 |
Ntg2 of Saccharomyces cerevisiae repairs the oxidation products of 8-hydroxyguanine.
Topics: Borohydrides; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; DNA; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA-Formamidopyrimidine Glycosylase; Dose-Response Relationship, Radiation; Escherichia coli Proteins; Gamma Rays; Guanine; Hydrogen Peroxide; Hydroxyl Radical; Iron; Macromolecular Substances; N-Glycosyl Hydrolases; Oxidation-Reduction; Piperidines; Protein Binding; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Substrate Specificity; Thymidine | 2001 |
Flavopiridol increases sensitization to gemcitabine in human gastrointestinal cancer cell lines and correlates with down-regulation of ribonucleotide reductase M2 subunit.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle Proteins; Cyclin D1; Cyclin E; Cysteine Endopeptidases; Cytochrome c Group; Deoxycytidine; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; E2F Transcription Factors; E2F1 Transcription Factor; Enzyme Inhibitors; Flavonoids; Gastrointestinal Neoplasms; Gemcitabine; Gene Expression Regulation, Enzymologic; Humans; Mitochondria; Multienzyme Complexes; Phosphorylation; Piperidines; Poly(ADP-ribose) Polymerases; Proteasome Endopeptidase Complex; Protein Subunits; Retinoblastoma Protein; Ribonucleotide Reductases; RNA, Messenger; Thymidine; Transcription Factors; Tritium; Tumor Cells, Cultured; Tumor Stem Cell Assay | 2001 |
Some aspects of the role of vitamin B12 in nucleic acid synthesis in a neoplastic C3H mouse cell strain. I. Growth studies.
Topics: Adenine; Adenosine; Animals; Cell Division; Cytidine; Deoxyadenosines; Deoxycytidine; Deoxyuridine; DNA, Neoplasm; Folic Acid; Guanine; Mice; Nucleic Acid Precursors; Nucleosides; Pyrimidines; Thymidine; Tumor Cells, Cultured; Uridine; Vitamin B 12 | 1970 |
Some aspects of the role of vitamin B12 in nucleic acid synthesis in a neoplastic C3H mouse cell strain. II. Incorporation of precursors.
Topics: Adenine; Animals; Carbon Radioisotopes; Cytidine; Deoxycytidine; Deoxyuridine; DNA, Neoplasm; Mice; Nucleic Acid Precursors; Nucleosides; Thymidine; Tumor Cells, Cultured; Uridine; Vitamin B 12 | 1970 |
S-acyl-2-thioethyl (SATE) pronucleotides are potent inhibitors of HIV-1 replication in T-lymphoid cells cross-resistant to deoxycytidine and thymidine analogs.
Topics: Anti-HIV Agents; Antiviral Agents; Cell Division; Cell Line; Cytarabine; Deoxycytidine; Deoxycytidine Kinase; Drug Resistance; HIV Infections; HIV-1; Humans; Microbial Sensitivity Tests; Prodrugs; Reverse Transcriptase Inhibitors; T-Lymphocytes; Thymidine; Thymidine Kinase; Virus Replication | 2002 |
A new method for the synthesis of oligodeoxyribonucleotides containing 4-N-alkoxycarbonyldeoxycytidine derivatives and their hybridization properties.
Topics: Adenosine; Alkaline Phosphatase; Animals; Base Sequence; Catalysis; Cattle; Chromatography, High Pressure Liquid; Deoxycytidine; DNA; Intestines; Molecular Sequence Data; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Nucleic Acid Hybridization; Oligodeoxyribonucleotides; Phosphodiesterase I; Phosphoric Diester Hydrolases; RNA; Snake Venoms; Thymidine; Uridine | 2002 |
Use of 5-[(76)Br]bromo-2'-fluoro-2'-deoxyuridine as a ligand for tumour proliferation: validation in an animal tumour model.
Topics: Animals; Autoradiography; Bromodeoxyuridine; Carbon Radioisotopes; Cell Division; Cimetidine; Deoxycytidine; DNA, Neoplasm; Fibrosarcoma; Flow Cytometry; Floxuridine; Gamma Cameras; Gemcitabine; Mice; Mice, Inbred C3H; Radionuclide Imaging; Radiopharmaceuticals; Scintillation Counting; Thymidine | 2002 |
One-pot two-step enzymatic coupling of pyrimidine bases to 2-deoxy-D-ribose-5-phosphate. A new strategy in the synthesis of stable isotope labeled deoxynucleosides.
Topics: Catalysis; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; Dihydroxyacetone Phosphate; Escherichia coli; Isotope Labeling; Magnetic Resonance Spectroscopy; Molecular Structure; Organisms, Genetically Modified; Phosphotransferases; Pyrimidines; Ribosemonophosphates; Saccharomyces cerevisiae; Thymidine; Thymidine Phosphorylase; Triose-Phosphate Isomerase; Uracil | 2002 |
Pharmacology of beta-L-thymidine and beta-L-2'-deoxycytidine in HepG2 cells and primary human hepatocytes: relevance to chemotherapeutic efficacy against hepatitis B virus.
Topics: Antiviral Agents; Carcinoma, Hepatocellular; Chromatography, High Pressure Liquid; Deoxycytidine; Half-Life; Hepatitis B; Hepatitis B virus; Hepatocytes; Humans; Liver Neoplasms; Phosphorylation; Thymidine; Tumor Cells, Cultured | 2002 |
Profiles of pyrimidine biosynthesis, salvage and degradation in disks of potato (Solanum tuberosum L.) tubers.
Topics: Carbon Radioisotopes; Culture Techniques; Cytidine; Cytidine Deaminase; Cytosine; Cytosine Deaminase; Deoxycytidine; Deoxycytidine Kinase; Deoxyribonucleosides; Enzymes; Multienzyme Complexes; Nucleoside Deaminases; Orotate Phosphoribosyltransferase; Orotidine-5'-Phosphate Decarboxylase; Pentosyltransferases; Phosphotransferases; Plant Stems; Pyrimidine Nucleosides; Pyrimidine Phosphorylases; Pyrimidines; Pyrimidinones; Solanum tuberosum; Thymidine; Thymidine Kinase; Uracil; Uridine; Uridine Kinase; Uridine Monophosphate; Uridine Phosphorylase | 2002 |
Comparison of multiple DNA adduct types in tumor adjacent human lung tissue: effect of cigarette smoking.
Topics: Aged; Deoxyadenosines; Deoxycytidine; DNA Adducts; DNA Damage; Female; Humans; Hydrocarbons; Lung Neoplasms; Male; Middle Aged; Smoking; Thymidine; Time Factors | 2002 |
Selective activation of deoxycytidine kinase by thymidine-5'-thiosulphate and release by deoxycytidine in human lymphocytes.
Topics: Cell-Free System; Deoxycytidine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; Enzyme Activation; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Lymph Nodes; Lymphocytes; Palatine Tonsil; Thiosulfates; Thymidine; Thymidine Kinase | 2003 |
Evaluation of (E)-2'-deoxy-2'-(fluoromethylene)cytidine on the 9L rat brain tumor model using MRI.
Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Division; Cell Line, Tumor; Cell Survival; Deoxycytidine; Dose-Response Relationship, Drug; Feasibility Studies; Glioma; Imaging, Three-Dimensional; Injections, Intraperitoneal; Magnetic Resonance Imaging; Male; Neoplasm Transplantation; Protons; Rats; Rats, Inbred F344; Thymidine; Treatment Outcome | 2003 |
Crystallographic characterization of an exocyclic DNA adduct: 3,N4-etheno-2'-deoxycytidine in the dodecamer 5'-CGCGAATTepsilonCGCG-3'.
Topics: Base Composition; Base Pairing; Crystallography, X-Ray; Deoxycytidine; DNA Adducts; Guanosine; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Thermodynamics; Thymidine | 2003 |
The conversion of 5-methyldeoxycytidine to thymidine in vitro and in vivo.
Topics: Amidohydrolases; Deoxycytidine; In Vitro Techniques; Nucleotides; Thymidine | 1957 |
Nucleotide interconversions. III. The incorporation in vitro of deoxycytidylate into the deoxycytidine and thymidine of deoxyribonucleic acid.
Topics: Deoxycytidine; DNA; In Vitro Techniques; Nucleosides; Nucleotides; RNA; Thymidine | 1961 |
Studies concerning inhibition of the synthesis of deoxycytidine by phosphorylated derivatives of thymidine.
Topics: Biochemical Phenomena; Deoxycytidine; Nucleosides; Nucleotides; Phosphorylation; Thymidine | 1960 |
On the nature of a sparing effect by thymidine on the utilization of deoxycytidine.
Topics: Deoxycytidine; Nucleosides; Nucleotides; Thymidine | 1962 |
Competition between 3H-thymidine and 5-methyldeoxycytidine incorporation into bone marrow deoxyribonucleic acid.
Topics: Bone Marrow; Deoxycytidine; DNA; Nucleosides; Thymidine | 1963 |
INHIBITION OF T'ANG TRACHOMA AGENT BY 5'-FLUORODEOXYCYTIDINE.
Topics: Chlamydia; Deoxycytidine; DNA; DNA, Viral; Metabolism; Nucleosides; Research; Thymidine; Trachoma; Virus Cultivation | 1963 |
EFFECT OF DEOXYCYTIDINE ON THE RATE OF BIOSYNTHESIS OF PHOSPHORYLATED DERIVATIVES OF THYMIDINE.
Topics: Carbon Isotopes; Chromatography; Deoxycytidine; Formates; Idoxuridine; Leukemia; Leukemia, Experimental; Leukemia, Lymphoid; Metabolism; Mice; Neoplasms; Neoplasms, Experimental; Nucleosides; Nucleotides; Pharmacology; Phosphorylation; Research; Thymidine | 1964 |
Preparation and purification of tritium-labeled thymidine, deoxycytidine, and adenosine.
Topics: Adenosine; Deoxycytidine; Nucleosides; Nucleotides; Thymidine; Tritium | 1961 |
Studies on polynucleotides. XV. Enzymic degradation. The mode of action of pancreatic deoxyribonuclease on thymidine, deoxycytidine, and deoxyadenosine polynucleotides.
Topics: Deoxyadenosines; Deoxycytidine; Deoxyribonucleases; DNA; Nucleosides; Nucleotides; Pancreas; Polynucleotides; Thymidine | 1962 |
Reactions of N,N-bis(2-chloroethyl)-p-aminophenylbutyric acid (chlorambucil) with 2'-deoxycytidine, 2'-deoxy-5-methylcytidine, and thymidine.
Topics: Antineoplastic Agents, Alkylating; Chlorambucil; Chromatography, High Pressure Liquid; Cytidine; Deoxycytidine; DNA Adducts; Magnetic Resonance Spectroscopy; Spectrometry, Mass, Electrospray Ionization; Thymidine | 2004 |
Glycosidic bond cleavage of pyrimidine nucleosides by low-energy electrons: a theoretical rationale.
Topics: Deoxycytidine; DNA Damage; Electrons; Glycosides; Kinetics; Models, Molecular; Pyrimidine Nucleosides; Thymidine | 2005 |
Bis(pivaloyloxymethyl) thymidine 5'-phosphate is a cell membrane-permeable precursor of thymidine 5'-phosphate in thymidine kinase deficient CCRF CEM cells.
Topics: Carbon Radioisotopes; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Kinetics; Nuclear Magnetic Resonance, Biomolecular; Permeability; Prodrugs; T-Lymphocytes; Thymidine; Thymidine Kinase; Thymidine Monophosphate | 2005 |
Reaction of glyoxal with 2'-deoxyguanosine, 2'-deoxyadenosine, 2'-deoxycytidine, cytidine, thymidine, and calf thymus DNA: identification of DNA adducts.
Topics: Cytidine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; DNA; DNA Adducts; Glyoxal; Magnetic Resonance Spectroscopy; Thymidine | 2005 |
Altered deoxyuridine and thymidine in plasma following capecitabine treatment in colorectal cancer patients.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Deoxyuridine; Female; Fluorouracil; Humans; Male; Thymidine | 2007 |
Cytidine is a novel substrate for wild-type concentrative nucleoside transporter 2.
Topics: Amino Acid Substitution; Animals; Antimetabolites, Antineoplastic; Biological Transport; Chlorocebus aethiops; COS Cells; Cytarabine; Cytidine; Deoxycytidine; Dose-Response Relationship, Drug; Gemcitabine; Genotype; Kinetics; Male; Membrane Transport Proteins; Mice; Thymidine; Transfection; Tritium; Uridine | 2006 |
Differential impact of thymidine analogue mutations on emtricitabine and lamivudine susceptibility.
Topics: Anti-HIV Agents; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; HIV-1; Lamivudine; Mutation; Thymidine | 2006 |
Development of new N-unprotected phosphoramidite building blocks having a silyl-type linker.
Topics: Deoxycytidine; Oligodeoxyribonucleotides; Organophosphorus Compounds; Thymidine | 2005 |
Mutagenesis of non-conserved active site residues improves the activity and narrows the specificity of human thymidine kinase 2.
Topics: Amino Acid Sequence; Animals; Binding Sites; Catalysis; Deoxycytidine; Drosophila melanogaster; Humans; Molecular Sequence Data; Mutagenesis; Nucleosides; Phosphotransferases (Alcohol Group Acceptor); Phylogeny; Purines; Substrate Specificity; Thymidine; Thymidine Kinase | 2007 |
Identification of DNA basepairing via tunnel-current decay.
Topics: Base Pairing; Deoxycytidine; DNA; Microscopy, Scanning Tunneling; Models, Molecular; Thymidine | 2007 |
[Anti-viral therapy of type B chronic hepatitis. 3. Future of anti-viral agents].
Topics: Adenine; Antiviral Agents; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Hepatitis B, Chronic; Humans; Interferons; Nucleic Acid Synthesis Inhibitors; Nucleosides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine | 2008 |
Self-Avoiding Molecular Recognition Systems (SAMRS).
Topics: 2-Aminopurine; Base Pairing; Deoxycytidine; DNA; DNA Primers; Inosine; Nucleic Acid Denaturation; Polymerase Chain Reaction; Thymidine | 2008 |
Extending thymidine kinase activity to the catalytic repertoire of human deoxycytidine kinase.
Topics: Adenosine Diphosphate; Biocatalysis; Crystallography, X-Ray; Cytarabine; Deoxyadenosines; Deoxycytidine; Deoxycytidine Kinase; Deoxyguanosine; Gemcitabine; Humans; Kinetics; Mutant Proteins; Mutation; Protein Structure, Secondary; Static Electricity; Substrate Specificity; Thymidine; Thymidine Kinase | 2009 |
High-performance capillary electrophoretic method for the quantification of global DNA methylation: application to methotrexate-resistant cells.
Topics: Deoxyadenosines; Deoxycytidine; Deoxyguanosine; DNA Methylation; Drug Resistance, Neoplasm; Electrophoresis, Capillary; Humans; Methotrexate; Reproducibility of Results; Thymidine | 2009 |
Anti-hepatitis B virus activity in vitro of combinations of tenofovir with nucleoside/nucleotide analogues.
Topics: Adenine; Antiviral Agents; Cell Line; Cell Survival; Deoxycytidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Nucleosides; Nucleotides; Organophosphonates; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine | 2009 |
Hepatitis B in HIV patients: what is the current treatment and what are the challenges?
Topics: Adenine; Antiviral Agents; Deoxycytidine; DNA, Viral; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B Surface Antigens; Hepatitis B, Chronic; HIV Infections; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Liver Cirrhosis; Nucleosides; Organophosphonates; Polyethylene Glycols; Pyrimidinones; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine; Transaminases | 2009 |
Role of TGF-beta1 (-509C>T) promoter polymorphism in susceptibility to cervical cancer.
Topics: Adult; Deoxycytidine; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Heterozygote; Homozygote; Humans; India; Middle Aged; Neoplasm Staging; Odds Ratio; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Risk Factors; Smoking; Thymidine; Tobacco, Smokeless; Transforming Growth Factor beta1; Uterine Cervical Neoplasms | 2009 |
Chelation-controlled regioselective alkylation of pyrimidine 2'-deoxynucleosides.
Topics: Alkylation; Chelating Agents; Crown Ethers; Deoxycytidine; Deoxyuridine; Electric Impedance; Pyrimidine Nucleosides; Solvents; Stereoisomerism; Substrate Specificity; Thymidine | 2010 |
Structural characterization of formaldehyde-induced cross-links between amino acids and deoxynucleosides and their oligomers.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Formaldehyde; Formic Acid Esters; Nuclear Magnetic Resonance, Biomolecular; Nucleosides; Oligonucleotides; Oligopeptides; Spectroscopy, Fourier Transform Infrared; Tandem Mass Spectrometry; Thymidine | 2010 |
Identification and characterization of mitochondrial factors modulating thymidine kinase 2 activity.
Topics: Animals; Chromatography, Gel; Deoxycytidine; Dideoxynucleosides; Enzyme Activation; Humans; Mitochondria; Phosphorylation; Rats; Recombinant Proteins; Thymidine; Thymidine Kinase; Zidovudine | 2010 |
Tissue specific distribution of pyrimidine deoxynucleoside salvage enzymes shed light on the mechanism of mitochondrial DNA depletion.
Topics: Animals; Chromatography, Ion Exchange; Cytosol; Deoxycytidine; Deoxycytidine Kinase; DNA, Mitochondrial; Liver; Lung; Mitochondria; Phosphorylation; Pyrimidines; Rats; Rats, Sprague-Dawley; Spleen; Thymidine; Thymidine Kinase | 2010 |
Pyrimidine deoxynucleoside and nucleoside reverse transcriptase inhibitor metabolism in the perfused heart and isolated mitochondria.
Topics: Animals; Anti-HIV Agents; Deoxycytidine; Male; Mitochondria, Heart; Myocardium; Nucleosides; Perfusion; Phosphorylation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors; Stavudine; Thymidine; Zalcitabine; Zidovudine | 2010 |
Structural and kinetic characterization of human deoxycytidine kinase variants able to phosphorylate 5-substituted deoxycytidine and thymidine analogues .
Topics: Amino Acid Substitution; Crystallography, X-Ray; Deoxycytidine; Deoxycytidine Kinase; Humans; Kinetics; Phosphorylation; Substrate Specificity; Thymidine | 2010 |
[Long-term therapy for chronic hepatitis B in HIV co-infected patients].
Topics: Adenine; Antiretroviral Therapy, Highly Active; Antiviral Agents; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B, Chronic; HIV Infections; Humans; Interferon alpha-2; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Pyrimidinones; Recombinant Proteins; Telbivudine; Tenofovir; Thymidine | 2010 |
[New drugs of treatment of patients with chronic hepatitis B].
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Emtricitabine; Hepatitis B, Chronic; Humans; Nucleosides; Organophosphonates; Pyrimidinones; Telbivudine; Tenofovir; Thymidine | 2011 |
Metabolism of deoxypyrimidines and deoxypyrimidine antiviral analogs in isolated brain mitochondria.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Deoxycytidine; Deoxyuridine; Dose-Response Relationship, Drug; Kinetics; Male; Mitochondria; Nucleotidases; Phosphorylation; Pyrimidine Nucleosides; Rats; Rats, Sprague-Dawley; Stavudine; Thymidine; Time Factors; Tritium; Zidovudine | 2012 |
Two thymidine kinases and one multisubstrate deoxyribonucleoside kinase salvage DNA precursors in Arabidopsis thaliana.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Biocatalysis; Cells, Cultured; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Deoxyribonucleosides; DNA, Bacterial; Isoenzymes; Kinetics; Molecular Sequence Data; Multigene Family; Mutagenesis, Insertional; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Phylogeny; Sequence Homology, Amino Acid; Substrate Specificity; Thymidine; Thymidine Kinase | 2012 |
The influence of HLA supertype on thymidine analogue associated with low peripheral fat in HIV.
Topics: Adenine; Anti-HIV Agents; Australia; Biomarkers; Blood Glucose; Body Fat Distribution; CD4 Lymphocyte Count; Deoxycytidine; Dideoxynucleosides; Drug Combinations; Drug Resistance, Viral; Emtricitabine; Female; Genotype; HIV Infections; HIV-Associated Lipodystrophy Syndrome; HLA Antigens; HLA-A1 Antigen; HLA-B8 Antigen; HLA-DQ Antigens; Humans; Lamivudine; Linkage Disequilibrium; Male; Middle Aged; Multicenter Studies as Topic; Organophosphonates; Predictive Value of Tests; Randomized Controlled Trials as Topic; Tenofovir; Thymidine | 2012 |
The physico-chemical "anatomy" of the tautomerization through the DPT of the biologically important pairs of hypoxanthine with DNA bases: QM and QTAIM perspectives.
Topics: Base Pairing; Computer Simulation; Deoxycytidine; DNA; Hydrogen Bonding; Hypoxanthine; Isomerism; Models, Chemical; Models, Molecular; Oxidation-Reduction; Quantum Theory; Thermodynamics; Thymidine | 2013 |
Effect of van der Waals interaction on the geometric and electronic properties of DNA nucleosides adsorbed on Cu(111) surface: a DFT study.
Topics: Adsorption; Copper; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Hydrophobic and Hydrophilic Interactions; Quantum Theory; Surface Properties; Thermodynamics; Thymidine; Water | 2013 |
Quantitative assessment of Tet-induced oxidation products of 5-methylcytosine in cellular and tissue DNA.
Topics: 5-Methylcytosine; Animals; Brain Chemistry; Cell Line, Tumor; Chromatography, High Pressure Liquid; Deoxycytidine; Dioxygenases; DNA; DNA-Binding Proteins; HEK293 Cells; Humans; Mice; Mixed Function Oxygenases; Oxidation-Reduction; Proto-Oncogene Proteins; Skin; Tandem Mass Spectrometry; Thymidine | 2013 |
Drug-resistance development differs between HIV-1-infected patients failing first-line antiretroviral therapy containing nonnucleoside reverse transcriptase inhibitors with and without thymidine analogues.
Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Deoxycytidine; Dideoxynucleosides; Drug Combinations; Drug Resistance, Viral; Emtricitabine; Female; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Tenofovir; Thymidine; Treatment Failure; Viral Load; Zidovudine | 2013 |
Attenuation of nucleoside and anti-cancer nucleoside analog drug uptake in prostate cancer cells by Cimicifuga racemosa extract BNO-1055.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Bromodeoxyuridine; Cell Line; Cell Proliferation; Cimicifuga; Deoxycytidine; Dose-Response Relationship, Drug; Equilibrative Nucleoside Transport Proteins; Fluorouracil; Gemcitabine; Humans; Male; Nucleosides; Phytotherapy; Plant Extracts; Prostate; Prostatic Neoplasms; RNA, Small Interfering; Saponins; Thymidine; Vidarabine | 2013 |
Delayed emergence of HIV-1 variants resistant to 4'-ethynyl-2-fluoro-2'-deoxyadenosine: comparative sequential passage study with lamivudine, tenofovir, emtricitabine and BMS-986001.
Topics: Adenine; Amino Acid Sequence; Anti-HIV Agents; Deoxyadenosines; Deoxycytidine; Drug Resistance, Multiple, Viral; Emtricitabine; HIV Infections; HIV-1; Human Immunodeficiency Virus Proteins; Humans; Lamivudine; Molecular Sequence Data; Molecular Structure; Organophosphonates; Tenofovir; Thymidine | 2014 |
Detection of oxidation products of 5-methyl-2'-deoxycytidine in Arabidopsis DNA.
Topics: Arabidopsis; Chromatography, High Pressure Liquid; Deoxycytidine; Deoxycytidine Monophosphate; DNA, Plant; Epigenesis, Genetic; Fluoresceins; Isotope Labeling; Molecular Structure; Nucleosides; Oxidation-Reduction; Tandem Mass Spectrometry; Thymidine | 2013 |
Nucleoside-catabolizing enzymes in mycoplasma-infected tumor cell cultures compromise the cytostatic activity of the anticancer drug gemcitabine.
Topics: Animals; Antimetabolites, Antineoplastic; Bacterial Proteins; Breast Neoplasms; Cell Line, Tumor; Deoxycytidine; Female; Gemcitabine; Humans; Mammary Neoplasms, Experimental; Mice; Mycoplasma hyorhinis; Mycoplasma Infections; Pyrimidine Phosphorylases; Tetrahydrouridine; Thymidine; Tumor Microenvironment | 2014 |
Photoswitchable formation of a DNA interstrand cross-link by a coumarin-modified nucleotide.
Topics: Base Sequence; Click Chemistry; Coumarins; Cycloaddition Reaction; Deoxyadenosines; Deoxycytidine; DNA; Oligodeoxyribonucleotides; Pyrimidine Nucleosides; Thymidine; Ultraviolet Rays | 2014 |
Mechanisms of hepatitis B virus resistance development.
Topics: Adenine; Amino Acid Substitution; Antiviral Agents; Deoxycytidine; Drug Resistance, Multiple, Viral; Emtricitabine; Guanine; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Organophosphonates; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Telbivudine; Tenofovir; Thymidine; Virus Replication | 2014 |
Comparison of the absolute level of epigenetic marks 5-methylcytosine, 5-hydroxymethylcytosine, and 5-hydroxymethyluracil between human leukocytes and sperm.
Topics: 5-Methylcytosine; Adult; Biomarkers; Chromatography, High Pressure Liquid; Cytosine; Deoxycytidine; DNA; DNA Methylation; Epigenesis, Genetic; Humans; Leukocytes; Male; Pentoxyl; Poland; Spectrometry, Mass, Electrospray Ionization; Spermatozoa; Tandem Mass Spectrometry; Thymidine; Up-Regulation | 2014 |
Evaluation of anti-HIV-1 mutagenic nucleoside analogues.
Topics: Anti-HIV Agents; Base Pair Mismatch; Base Pairing; Base Sequence; Deoxycytidine; Drug Design; High-Throughput Screening Assays; HIV Reverse Transcriptase; HIV-1; Molecular Sequence Data; Mutagenesis; Mutagens; Nucleic Acid Denaturation; Predictive Value of Tests; Reverse Transcriptase Inhibitors; Reverse Transcription; Thermodynamics; Thymidine; Time Factors | 2015 |
Reactivity of damaged pyrimidines: formation of a Schiff base intermediate at the glycosidic bond of saturated dihydrouridine.
Topics: Catalysis; Deoxycytidine; Deoxyribose; Deoxyuridine; DNA Glycosylases; Glycosylation; Hydrogen-Ion Concentration; Hydrogenation; Isomerism; Magnetic Resonance Spectroscopy; Palladium; Pyrimidines; Schiff Bases; Tandem Mass Spectrometry; Thymidine | 2015 |
Combined chemoassay and mass spectrometric approach to study the reactive potential of electrophiles towards deoxynucleosides as model for DNA.
Topics: Benzoquinones; Chromatography, Liquid; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Deoxyribonucleosides; DNA; DNA Adducts; DNA Damage; Mutagens; Naphthoquinones; Oxidants; Tandem Mass Spectrometry; Thymidine | 2016 |
Molecular recognition of a lipophilic guanosine derivative in Langmuir films at the air-water interface.
Topics: Air; Air Pressure; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Lipids; Models, Chemical; Surface Properties; Thymidine; Water | 2017 |
Replication studies of carboxymethylated DNA lesions in human cells.
Topics: Base Sequence; CRISPR-Cas Systems; Deoxyadenosines; Deoxycytidine; DNA; DNA Adducts; DNA Damage; DNA Polymerase II; DNA Repair; DNA Replication; DNA-Binding Proteins; DNA-Directed DNA Polymerase; Gene Editing; HEK293 Cells; Humans; Mutation; Poly-ADP-Ribose Binding Proteins; Thymidine; Tumor Suppressor Protein p53 | 2017 |
Normalized Retention Time for Targeted Analysis of the DNA Adductome.
Topics: Chromatography, High Pressure Liquid; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; DNA Adducts; Hydrophobic and Hydrophilic Interactions; Nanotechnology; Stereoisomerism; Tandem Mass Spectrometry; Thymidine | 2018 |
Mechanisms of gemcitabine oral absorption as determined by in situ intestinal perfusions in mice.
Topics: Administration, Oral; Animals; Cell Membrane; Cell Membrane Permeability; Deoxycytidine; Dilazep; Equilibrative Nucleoside Transport Proteins; Female; Gemcitabine; Inhibitory Concentration 50; Intestinal Absorption; Male; Membrane Transport Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Oral Mucosal Absorption; Perfusion; Thymidine | 2019 |
Effects of Urea on the Reactions of Nucleosides with Hypobromous Acid.
Topics: Bromates; Chromatography, High Pressure Liquid; Deoxycytidine; Deoxyguanosine; Halogenation; Nucleosides; Phosphates; Potassium Compounds; Spectrometry, Mass, Electrospray Ionization; Thymidine; Urea | 2019 |
Incorporation characteristics of exogenous 15N-labeled thymidine, deoxyadenosine, deoxyguanosine and deoxycytidine into bacterial DNA.
Topics: Bays; Biomass; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; DNA, Bacterial; Ecosystem; Japan; Kinetics; Lakes; Microbial Consortia; Nitrogen Isotopes; Thymidine | 2020 |
Deoxynucleoside therapy for respiratory involvement in adult patients with thymidine kinase 2-deficient myopathy.
Topics: Adolescent; Adult; Child; Child, Preschool; Deoxycytidine; Female; Humans; Middle Aged; Mitochondrial Myopathies; Respiratory Muscles; Thymidine; Thymidine Kinase; Vital Capacity; Young Adult | 2020 |
Uric Acid as a Photosensitizer in the Reaction of Deoxyribonucleosides with UV Light of Wavelength Longer than 300 nm: Identification of Products from 2'-Deoxycytidine.
Topics: Bromates; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Deoxyribonucleosides; DNA; Ethanol; Free Radical Scavengers; Hypochlorous Acid; Kinetics; Peroxynitrous Acid; Photochemical Processes; Photosensitizing Agents; Singlet Oxygen; Sodium Azide; Thymidine; Ultraviolet Rays; Uric Acid | 2021 |
XRCC1 Prevents Replication Fork Instability during Misincorporation of the DNA Demethylation Bases 5-Hydroxymethyl-2'-Deoxycytidine and 5-Hydroxymethyl-2'-Deoxyuridine.
Topics: 5-Methylcytosine; Cell Line; Cell Survival; Deoxycytidine; DNA Damage; DNA Demethylation; DNA Replication; Epigenesis, Genetic; Genomic Instability; Humans; Replication Origin; Thymidine; X-ray Repair Cross Complementing Protein 1 | 2022 |
FANCD2 maintains replication fork stability during misincorporation of the DNA demethylation products 5-hydroxymethyl-2'-deoxycytidine and 5-hydroxymethyl-2'-deoxyuridine.
Topics: Deoxycytidine; DNA Demethylation; DNA Replication; Fanconi Anemia; Fanconi Anemia Complementation Group D2 Protein; Humans; Thymidine | 2022 |