Page last updated: 2024-08-17

thymidine and deoxy-4-thiothymidine

thymidine has been researched along with deoxy-4-thiothymidine in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19902 (9.09)18.7374
1990's3 (13.64)18.2507
2000's7 (31.82)29.6817
2010's10 (45.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Horwitz, JP; Kessel, D; Meltsner, BR; Palomino, E1
Connolly, BA; Newman, PC1
Hofer, B; Köster, H1
Connolly, BA; Nikiforov, TT; Shaw, WV; Thomas, CD1
Bartholomew, B; Braun, BR; Geiduschek, EP; Kassavetis, GA1
Haber, MT; Jerina, DM; Rao, TV; Sayer, JM1
Karran, P; Massey, A; Xu, YZ1
Chepanoske, CL; David, SS; Golinelli-Cohen, MP; Lombard, M; Lukianova, OA1
Kool, ET; Sintim, HO1
Harada, Y; Ichimura, T; Suzuki, T; Xu, YZ1
Karran, P; Massey, A; Reelfs, O; Storey, A; Xu, YZ1
Lavrik, O; Petruseva, I; Saintomé, C; Salas, TR1
Boddy, AV; Heer, R; Karran, P; Newell, DR; O'Toole, K; Pridgeon, SW; Robinson, M; Taylor, GA; Xu, YZ1
Karran, P; Macpherson, P; Reelfs, O; Ren, X; Xu, YZ; Young, AR1
Gemenetzidis, E; Shavorskaya, O; Trigiante, G; Xu, YZ1
Karran, P; Reelfs, O; Young, AR1
Gu, H; Zhang, J; Zhang, X1
Jitsuzaki, D; Nishimoto, A; Onizuka, K; Oshiro, I; Sasaki, S; Taniguchi, Y1
Agostiano, A; Cosma, P; Fini, P; Fraix, A; Longobardi, F; Losito, I; Rizzi, V; Sortino, S; Ventrella, A1
Corral, I; Crespo-Hernández, CE; Granucci, G; Martínez-Fernández, L; Persico, M; Pollum, M1
Benhida, R; Coulon, S; Désert, A; Drujon, T; Gérard-Hirne, T; Guérineau, V; Guianvarc'h, D; Michel, BY; Sachon, E; Saintomé, C; Thiebaut, F1
Cui, CX; Xie, BB1

Other Studies

22 other study(ies) available for thymidine and deoxy-4-thiothymidine

ArticleYear
Synthesis and in vitro evaluation of some modified 4-thiopyrimidine nucleosides for prevention or reversal of AIDS-associated neurological disorders.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:1

    Topics: AIDS Dementia Complex; Animals; Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Chemistry, Physical; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Humans; Kinetics; Molecular Structure; Phosphorylation; Pyrimidine Nucleosides; Rabbits; Stavudine; T-Lymphocytes; Thymidine Kinase; Thymus Gland; Zidovudine

1990
Synthesis and properties of oligonucleotides containing 4-thiothymidine, 5-methyl-2-pyrimidinone-1-beta-D(2'-deoxyriboside) and 2-thiothymidine.
    Nucleic acids research, 1989, Jul-11, Volume: 17, Issue:13

    Topics: Base Sequence; Indicators and Reagents; Magnetic Resonance Spectroscopy; Oligodeoxyribonucleotides; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Thymidine

1989
Enzymatic synthesis, ligation, and restriction of DNA containing deoxy-4-thiothymidine.
    Nucleic acids research, 1981, Feb-25, Volume: 9, Issue:4

    Topics: Bacteriophages; DNA Ligases; DNA Polymerase I; DNA Replication; DNA Restriction Enzymes; DNA, Single-Stranded; DNA, Viral; Electrophoresis, Agar Gel; Escherichia coli; Phosphoric Diester Hydrolases; Spectrophotometry, Ultraviolet; Thymidine

1981
Determination of sequence specificity between a plasmid replication initiator protein and the origin of replication.
    Journal of molecular biology, 1995, Dec-01, Volume: 254, Issue:3

    Topics: Bacterial Proteins; Base Sequence; Binding Sites; Binding, Competitive; Cross-Linking Reagents; DNA Damage; DNA Replication; DNA Topoisomerases, Type I; DNA-Binding Proteins; Models, Genetic; Molecular Sequence Data; Oligonucleotides; Plasmids; Protein Binding; Replication Origin; Thymidine

1995
Probing close DNA contacts of RNA polymerase III transcription complexes with the photoactive nucleoside 4-thiodeoxythymidine.
    The Journal of biological chemistry, 1994, Jul-08, Volume: 269, Issue:27

    Topics: Base Sequence; DNA; DNA Probes; Molecular Sequence Data; Photochemistry; RNA Polymerase III; RNA, Ribosomal, 5S; RNA, Transfer, Tyr; Saccharomyces cerevisiae; Thymidine; Transcription, Genetic

1994
Incorporation of 4-thiothymidine into DNA by the Klenow fragment and HIV-1 reverse transcriptase.
    Bioorganic & medicinal chemistry letters, 2000, May-01, Volume: 10, Issue:9

    Topics: Base Pairing; DNA; DNA Polymerase I; DNA Primers; Escherichia coli; HIV Reverse Transcriptase; Kinetics; Spectrophotometry, Ultraviolet; Templates, Genetic; Thymidine

2000
Ambiguous coding is required for the lethal interaction between methylated DNA bases and DNA mismatch repair.
    DNA repair, 2002, Apr-29, Volume: 1, Issue:4

    Topics: Base Pair Mismatch; Cell Line, Transformed; Cell Survival; Cell Transformation, Viral; DNA; DNA Methylation; DNA Primers; DNA Repair; Humans; Open Reading Frames; Thymidine; Thymine; Tumor Cells, Cultured

2002
A residue in MutY important for catalysis identified by photocross-linking and mass spectrometry.
    Biochemistry, 2004, Jan-27, Volume: 43, Issue:3

    Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Arginine; Base Pair Mismatch; Catalysis; Chromatography, Liquid; Cross-Linking Reagents; DNA Glycosylases; DNA, Bacterial; Escherichia coli Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleic Acid Heteroduplexes; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Thymidine; Ultraviolet Rays

2004
Enhanced base pairing and replication efficiency of thiothymidines, expanded-size variants of thymidine.
    Journal of the American Chemical Society, 2006, Jan-18, Volume: 128, Issue:2

    Topics: Base Pairing; DNA; DNA Polymerase I; DNA Replication; Escherichia coli; Escherichia coli Proteins; Kinetics; Models, Molecular; Nucleic Acid Hybridization; Thymidine

2006
Triplet formation of 4-thiothymidine and its photosensitization to oxygen studied by time-resolved thermal lensing technique.
    The journal of physical chemistry. B, 2007, May-17, Volume: 111, Issue:19

    Topics: Hot Temperature; Molecular Structure; Oxygen; Photochemistry; Thymidine; Time Factors

2007
Thiothymidine plus low-dose UVA kills hyperproliferative human skin cells independently of their human papilloma virus status.
    Molecular cancer therapeutics, 2007, Volume: 6, Issue:9

    Topics: Animals; Apoptosis; Blotting, Western; Cell Proliferation; Cells, Cultured; Combined Modality Therapy; DNA Damage; Female; Fibroblasts; Fibrosarcoma; Flow Cytometry; Humans; Keratinocytes; Mice; Middle Aged; Octreotide; Papillomaviridae; Papillomavirus Infections; Skin; Skin Neoplasms; Thymidine; Tumor Suppressor Protein p53; Ultraviolet Rays

2007
Evidence for direct contact between the RPA3 subunit of the human replication protein A and single-stranded DNA.
    Nucleic acids research, 2009, Volume: 37, Issue:1

    Topics: Binding Sites; DNA-Binding Proteins; DNA, Single-Stranded; Humans; Oligonucleotides; Protein Binding; Protein Subunits; Replication Protein A; Thymidine

2009
Thiothymidine combined with UVA as a potential novel therapy for bladder cancer.
    British journal of cancer, 2011, Jun-07, Volume: 104, Issue:12

    Topics: Animals; Apoptosis; Cell Line, Tumor; DNA Damage; Female; Humans; Quinazolines; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Thiophenes; Thymidine; Ultraviolet Therapy; Urinary Bladder Neoplasms

2011
Identification of potentially cytotoxic lesions induced by UVA photoactivation of DNA 4-thiothymidine in human cells.
    Nucleic acids research, 2011, Volume: 39, Issue:22

    Topics: Animals; Cell Line; Cricetinae; DNA; DNA Damage; DNA Repair; Humans; Mutagenesis; Oligonucleotides; Pyrimidine Dimers; Reactive Oxygen Species; Skin; Thymidine; Ultraviolet Rays

2011
Topical 4-thiothymidine is a viable photosensitiser for the photodynamic therapy of skin malignancies.
    The Journal of dermatological treatment, 2013, Volume: 24, Issue:3

    Topics: Apoptosis; Biopsy; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Line, Tumor; Humans; Photochemotherapy; Photosensitizing Agents; Skin; Skin Absorption; Skin Neoplasms; Thymidine; Ultraviolet Rays

2013
4-Thiothymidine sensitization of DNA to UVA offers potential for a novel photochemotherapy.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2012, Volume: 11, Issue:1

    Topics: Animals; Cell Death; DNA; Models, Animal; Photochemotherapy; Thymidine; Ultraviolet Rays

2012
Exploring the binding of 4-thiothymidine with human serum albumin by spectroscopy, atomic force microscopy, and molecular modeling methods.
    Carbohydrate research, 2014, Jan-30, Volume: 384

    Topics: Binding Sites; Circular Dichroism; Humans; Microscopy, Atomic Force; Models, Molecular; Serum Albumin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Thymidine

2014
Site-specific modification of the 6-amino group of adenosine in RNA by an interstrand functionality-transfer reaction with an s-functionalized 4-thiothymidine.
    Chembiochem : a European journal of chemical biology, 2015, May-26, Volume: 16, Issue:8

    Topics: Adenosine; Base Sequence; Binding Sites; Copper; Oligodeoxyribonucleotides; RNA; Sulfur; Thymidine

2015
Rose Bengal-photosensitized oxidation of 4-thiothymidine in aqueous medium: evidence for the reaction of the nucleoside with singlet state oxygen.
    Physical chemistry chemical physics : PCCP, 2015, Oct-21, Volume: 17, Issue:39

    Topics: Light; Models, Molecular; Oxidation-Reduction; Photolysis; Photosensitizing Agents; Rose Bengal; Singlet Oxygen; Thionucleosides; Thymidine

2015
Decoding the Molecular Basis for the Population Mechanism of the Triplet Phototoxic Precursors in UVA Light-Activated Pyrimidine Anticancer Drugs.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2017, Feb-21, Volume: 23, Issue:11

    Topics: Antineoplastic Agents; Electron Transport; Energy Transfer; Molecular Dynamics Simulation; Photosensitizing Agents; Prodrugs; Pyrimidines; Quantum Theory; Solvents; Spectrophotometry; Thermodynamics; Thymidine; Ultraviolet Rays

2017
Photoactivatable oligonucleotide probes to trap single-stranded DNA binding proteins: Updating the potential of 4-thiothymidine from a comparative study.
    Biochimie, 2018, Volume: 154

    Topics: Humans; Molecular Probes; Oligonucleotides; Replication Protein A; Thymidine

2018
Theoretical studies on photo-induced cycloaddition and (6-4) reactions of the thymidine:4-thiothymidine dimer in a DNA duplex.
    Physical chemistry chemical physics : PCCP, 2019, Jan-23, Volume: 21, Issue:4

    Topics: Cycloaddition Reaction; Dimerization; DNA; Models, Chemical; Nucleic Acid Conformation; Thymidine

2019