thymidine has been researched along with brivudine in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (60.98) | 18.7374 |
| 1990's | 5 (12.20) | 18.2507 |
| 2000's | 8 (19.51) | 29.6817 |
| 2010's | 3 (7.32) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bobek, M; Cheng, YC; Dutschman, G; Grill, S; Kavai, I; Sharma, RA | 1 |
| Balzarini, J; Barr, PJ; De Clercq, E; Descamps, J; Giziewicz, J; Robins, MJ | 1 |
| De Winter, H; Herdewijn, P | 1 |
| Clercq, ED; Folkers, G; Marquez, VE; Russ, P; Scapozza, L; Schelling, P | 1 |
| Black, DH; Eberle, R; Focher, F; Gambino, JJ; Lossani, A; Maioli, A; Medveczky, M; Medveczky, P; Shugar, D; Spadari, S; Verri, A; Wright, GE | 1 |
| Claessens, F; Dehaen, W; Helsen, C; Karypidou, K; Pannecouque, C; Persoons, L; Quevedo, MA; Ribone, SR | 1 |
| Bull, CO; Landry, ML; Milstone, LM; Reuveni, H; Schwartz, PM | 1 |
| Bryson, YJ | 1 |
| Coen, DM; Irmiere, AF; Jacobson, JG; Kerns, KM | 1 |
| De Clercq, E; Griengl, H; Hayden, W; Penn, G; Rosenwirth, B | 1 |
| De Clercq, E; Huyghe, P; Maudgal, PC | 1 |
| Coen, DM; Fleming, HE; Leslie, LK; Retondo, MJ | 1 |
| De Clercq, E; Konno, K; Shigeta, S; Verbruggen, A; Yokota, T | 1 |
| Dunkel, EC; Geary, PA; Imperia, PS; Lass, JH; Lazarus, HM; Pavan-Langston, D | 1 |
| Lee, JJ; Lin, TS; Mancini, WR; Otto, MJ; Prusoff, WH; Siegel, SA | 1 |
| Harmenberg, J | 1 |
| Friedman-Kien, AE; Klein, RJ | 1 |
| Darby, G; Field, H; McMillan, A | 1 |
| Gentry, GA; Veerisetty, V | 2 |
| de Clercq, E | 1 |
| Honess, RW; O'Hare, P; Young, D | 1 |
| Fyfe, JA | 1 |
| Allaudeen, HS; Chen, HC; De Clercq, E; Liu, YX; Zhang, ZX | 1 |
| Maudgal, PC; Missotten, L; Van Damme, B | 1 |
| Kálmán, A; Kovács, T; Otvös, L; Párkányi, L; Szabolcs, A | 1 |
| Marmer, DJ; Steele, RW | 1 |
| Arvin, AM; Cohen, PS; De Clercq, E; Koropchak, CM; Smith, SD; Wittek, AE | 1 |
| De Clercq, E; Descamps, J; Maudgal, PC; Missotten, L; Wijnhoven, J | 1 |
| Albert, DM; De Clercq, E; Hettinger, ME; Lin, TS; Park, NH; Pavan-Langston, D | 1 |
| Docherty, JJ; Wilber, BA | 1 |
| Smith, G | 1 |
| Focher, F; Priori, G; Spadari, S; Tondelli, L; Verri, A | 1 |
| Johansson, M; Karlsson, A; Zheng, X | 2 |
| Johansson, M; Karlsson, A; Lundberg, M; Zheng, X | 1 |
| Balzarini, J; Bianchi, V; Franzolin, E; Hernández, AI; Pérez-Pérez, MJ; Rampazzo, C | 1 |
| Balzarini, J; Jasamai, M; Simons, C | 1 |
| Eriksson, S; Wang, L | 1 |
| Gu, M; Jiang, H; Sun, Y; Zheng, X | 1 |
| Medin, JA; Neschadim, A | 1 |
4 review(s) available for thymidine and brivudine
| Article | Year |
|---|---|
Promising new antiviral drugs.
Topics: Acyclovir; Animals; Antiviral Agents; Bromodeoxyuridine; Cytomegalovirus Infections; Foscarnet; Ganciclovir; Herpes Simplex; Herpes Zoster; Humans; Interferons; Phosphonoacetic Acid; Ribavirin; Thymidine; Zidovudine | 1988 |
Physical and biological consequences of incorporation of antiviral agents into virus DNA.
Topics: Acyclovir; Antiviral Agents; Bromodeoxyuridine; Cytarabine; Dideoxynucleosides; DNA, Viral; Idoxuridine; Protein Biosynthesis; Ribavirin; Simplexvirus; Structure-Activity Relationship; Thymidine; Thymine Nucleotides; Transcription, Genetic; Vidarabine | 1984 |
Interactions between virus and antiviral compounds in the host cell.
Topics: Acyclovir; Animals; Antiviral Agents; Bromodeoxyuridine; Cell Line; Cytomegalovirus; Deoxyribonucleotides; Diphosphates; DNA Replication; DNA, Viral; Drug Resistance, Microbial; Embryo, Mammalian; Herpesviridae; Herpesvirus 4, Human; Humans; Idoxuridine; Kidney; Lung; Nucleic Acid Synthesis Inhibitors; Nucleosides; Phosphorylation; Simplexvirus; Thymidine; Thymidine Kinase | 1984 |
Nucleoside analogues as antiviral agents.
Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Arabinonucleosides; Bromodeoxyuridine; Chemical Phenomena; Chemistry; Cytarabine; Deoxyuridine; Guanine; Herpesviridae Infections; Humans; Idoxuridine; Nucleosides; Ribavirin; Thymidine; Virus Diseases; Viruses | 1981 |
37 other study(ies) available for thymidine and brivudine
| Article | Year |
|---|---|
Acetylenic nucleosides. 4. 1-beta-D-arabinofuranosyl-5-ethynylcytosine. Improved synthesis and evaluation of biochemical and antiviral properties.
Topics: Antiviral Agents; Cytarabine; Deamination; Phosphorylation; Simplexvirus | 1987 |
Nucleic acid related compounds. 40. Synthesis and biological activities of 5-alkynyluracil nucleosides.
Topics: Alkynes; Animals; Cell Survival; Idoxuridine; Leukemia L1210; Mice; Rabbits; Simplexvirus; Substrate Specificity; Thymidylate Synthase; Virus Replication | 1983 |
Understanding the binding of 5-substituted 2'-deoxyuridine substrates to thymidine kinase of herpes simplex virus type-1.
Topics: Antiviral Agents; Binding Sites; Deoxyuridine; Enzyme Inhibitors; Models, Molecular; Molecular Conformation; Molecular Structure; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Simplexvirus; Substrate Specificity; Thermodynamics; Thymidine Kinase | 1996 |
Synthesis and biological evaluation of 5-substituted derivatives of the potent antiherpes agent (north)-methanocarbathymine.
Topics: Antiviral Agents; Cell Division; Cell Line; Cell Line, Tumor; Herpesviridae; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Humans; Kinetics; Molecular Conformation; Poxviridae; Pyrimidine Nucleosides; Structure-Activity Relationship; Thymidine Kinase; Thymine; Vaccinia virus; Viral Plaque Assay | 2003 |
Sensitivity of monkey B virus (Cercopithecine herpesvirus 1) to antiviral drugs: role of thymidine kinase in antiviral activities of substrate analogs and acyclonucleosides.
Topics: Acyclovir; Amino Acid Sequence; Animals; Antiviral Agents; Chlorocebus aethiops; Deoxyuridine; Enzyme Inhibitors; Guanine; Herpesvirus 1, Cercopithecine; Microbial Sensitivity Tests; Molecular Sequence Data; Nucleosides; Phosphorylation; Substrate Specificity; Thymidine; Thymidine Kinase; Vero Cells | 2007 |
Synthesis, biological evaluation and molecular modeling of a novel series of fused 1,2,3-triazoles as potential anti-coronavirus agents.
Topics: Antiviral Agents; Catalytic Domain; Cell Line, Tumor; Coronavirus; Coronavirus 3C Proteases; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Protein Binding; Structure-Activity Relationship; Triazoles; Viral Proteins | 2018 |
Antiviral activity of 5-iodo-2'-deoxyuridine and related drugs in human keratinocytes infected in vitro with herpes simplex virus type 1.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Drug Interactions; Guinea Pigs; Herpes Simplex; Humans; Idoxuridine; Keratinocytes; Simplexvirus; Thymidine; Thymidine Phosphorylase; Thymine; Zidovudine | 1991 |
Low levels of herpes simplex virus thymidine- thymidylate kinase are not limiting for sensitivity to certain antiviral drugs or for latency in a mouse model.
Topics: Acyclovir; Animals; Antiviral Agents; Bromodeoxyuridine; Drug Resistance, Microbial; Herpes Simplex; Humans; Mice; Mutation; Nucleoside-Phosphate Kinase; Phosphotransferases; Simplexvirus; Temperature; Thymidine; Thymidine Kinase; Thymine Nucleotides; Trigeminal Ganglion; Tumor Cells, Cultured; Vero Cells | 1989 |
Phosphonoformate and phosphonoacetate derivatives of 5-substituted 2'-deoxyuridines: synthesis and antiviral activity.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cell Line; Chemical Phenomena; Chemistry; Deoxyuridine; Foscarnet; Herpes Simplex; Mice; Organophosphorus Compounds; Pharmaceutical Preparations; Phosphonoacetic Acid; Prodrugs; Rabbits; Simplexvirus; Thymidine; Vero Cells | 1988 |
Experimental thymidine kinase-deficient HSV-1 keratitis: therapeutic attempts.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Drug Evaluation, Preclinical; Floxuridine; Keratitis, Dendritic; Rabbits; Thymidine; Thymidine Kinase; Trifluridine | 1987 |
Sensitivity of arabinosyladenine-resistant mutants of herpes simplex virus to other antiviral drugs and mapping of drug hypersensitivity mutations to the DNA polymerase locus.
Topics: Acyclovir; Antiviral Agents; Arabinofuranosyluracil; Arabinonucleosides; Bromodeoxyuridine; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Genes, Viral; Idoxuridine; Mutation; Phosphonoacetic Acid; Simplexvirus; Thymidine; Vidarabine | 1985 |
Incorporation of (E)-5-(2-iodovinyl)-2'-deoxyuridine into deoxyribonucleic acids of varicella-zoster virus (TK+ and TK- strains)-infected cells.
Topics: Autoradiography; Biological Transport; Bromodeoxyuridine; Cells, Cultured; DNA, Viral; Dose-Response Relationship, Drug; Herpesvirus 3, Human; Humans; Idoxuridine; Nucleic Acid Hybridization; Thymidine; Thymidine Kinase; Time Factors; Virus Replication | 1987 |
An in vitro study of ophthalmic antiviral agent toxicity on rabbit corneal epithelium.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cell Survival; Cornea; Deoxyuridine; Epithelium; Idoxuridine; In Vitro Techniques; Rabbits; Thymidine; Trifluridine | 1988 |
Effect of eight antiviral drugs on the reactivation of herpes simplex virus in explant cultures of latently infected mouse trigeminal ganglia.
Topics: Acyclovir; Animals; Antibodies, Viral; Antiviral Agents; Arabinofuranosyluracil; Arabinonucleosides; Bromodeoxyuridine; Culture Media; Culture Techniques; Cytarabine; Foscarnet; Mice; Mice, Hairless; Neutralization Tests; Phosphonoacetic Acid; Simplexvirus; Thymidine; Trigeminal Nerve; Vidarabine Phosphate; Virus Activation | 1984 |
The sensitivity of acyclovir-resistant mutants of herpes simplex virus to other antiviral drugs.
Topics: Acyclovir; Antiviral Agents; Arabinonucleosides; Bromodeoxyuridine; Drug Resistance, Microbial; Foscarnet; Guanine; Microbial Sensitivity Tests; Mutation; Phosphonoacetic Acid; Simplexvirus; Thymidine; Trifluridine; Vidarabine | 1981 |
5-Methoxymethyldeoxyuridine-resistant mutants of herpes simplex virus type 1.
Topics: Acyclovir; Animals; Arabinonucleosides; Bromodeoxyuridine; Cell Line; Deoxyuridine; Drug Resistance, Microbial; Enzyme Induction; Guanine; Mice; Mutation; Phosphonoacetic Acid; Simplexvirus; Thymidine; Thymidine Kinase | 1981 |
Comparison of thymidine kinase activities indiced in cells productively infected with herpesvirus saimiri and herpes simplex virus.
Topics: Acyclovir; Animals; Aotus trivirgatus; Bromodeoxyuridine; Cell Line; Chlorocebus aethiops; Enzyme Induction; Guanine; Herpesvirus 2, Saimiriine; Idoxuridine; Mutation; Simplexvirus; Thymidine; Thymidine Kinase | 1982 |
Differential phosphorylation of (E)-5-(2-bromovinyl)-2'-deoxyuridine monophosphate by thymidylate kinases from herpes simplex viruses types 1 and 2 and varicella zoster virus.
Topics: Bromodeoxyuridine; Cytosol; Herpesvirus 3, Human; Kinetics; Phosphorylation; Simplexvirus; Thymidine; Thymidine Kinase | 1982 |
Alterations in substrate specificity and physicochemical properties of deoxythymidine kinase of a drug-resistant herpes simplex virus type 1 mutant.
Topics: Arabinonucleosides; Blood; Bromodeoxyuridine; Deoxyuridine; Drug Resistance, Microbial; Enzyme Induction; Hot Temperature; Mutation; Phosphorylation; Simplexvirus; Substrate Specificity; Thymidine; Thymidine Kinase | 1983 |
Effect of (E)-5-(2-bromovinyl)-2'-deoxyuridine on several parameters of Epstein-Barr virus infection.
Topics: Acyclovir; Animals; Antiviral Agents; Arabinonucleosides; Bromodeoxyuridine; Burkitt Lymphoma; Callitrichinae; Cell Line; Drug Evaluation, Preclinical; Herpesviridae Infections; Herpesvirus 4, Human; Humans; Hybrid Cells; In Vitro Techniques; Thymidine; Virus Cultivation; Virus Replication | 1984 |
Corneal epithelial dysplasia after trifluridine use.
Topics: Age Factors; Aged; Antiviral Agents; Bromodeoxyuridine; Cornea; Corneal Diseases; Epithelium; Humans; Keratitis, Dendritic; Male; Microscopy, Phase-Contrast; Thymidine; Trifluridine | 1983 |
Crystal and molecular structure of (E)-5-(2-bromovinyl-2'-deoxyuridine).
Topics: Bromodeoxyuridine; Models, Molecular; Molecular Conformation; Thymidine; X-Ray Diffraction | 1983 |
Comparison of flow cytometric analysis and [3H]thymidine incorporation for measurement of the effects of drug toxicity on lymphocyte stimulation.
Topics: Bromodeoxyuridine; Cytarabine; DNA; Drug-Related Side Effects and Adverse Reactions; Flow Cytometry; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Thymidine | 1983 |
Effects of (E)-5-(2-bromovinyl)-2'-deoxyuridine on proliferation of human fibroblasts, peripheral blood mononuclear cells, and granulocyte-monocyte progenitor cells in vitro.
Topics: Antiviral Agents; Bromodeoxyuridine; Cell Division; Colony-Forming Units Assay; Fibroblasts; Granulocytes; Humans; In Vitro Techniques; Monocytes; Thymidine | 1983 |
Experimental stroma herpes simplex keratitis. Influence of treatment with topical bromovinyldeoxyuridine and trifluridine.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Corneal Diseases; Disease Models, Animal; Drug Administration Schedule; Keratitis, Dendritic; Ophthalmic Solutions; Rabbits; Thymidine; Trifluridine | 1982 |
Ac2IDU, BVDU, and thymine arabinoside therapy in experimental herpes keratitis.
Topics: Animals; Antiviral Agents; Arabinonucleosides; Bromodeoxyuridine; Drug Evaluation, Preclinical; Idoxuridine; Keratitis, Dendritic; Male; Petrolatum; Rabbits; Sodium Chloride; Thymidine; Vidarabine | 1981 |
Analysis of the thymidine kinase of a herpes simplex virus type 1 isolate that exhibits resistance to (E)-5-(2-bromovinyl)-2'-deoxyuridine.
Topics: Acyclovir; Amino Acid Sequence; Antiviral Agents; Base Sequence; Binding Sites; Bromodeoxyuridine; Deoxyuridine; Drug Resistance, Microbial; Herpesvirus 1, Human; Humans; Kinetics; Molecular Sequence Data; Phosphonoacetic Acid; Phosphorylation; Point Mutation; Sequence Analysis, DNA; Thymidine; Thymidine Kinase; Vidarabine | 1994 |
In vitro sensitivity of macropodid herpesvirus 2 to selected anti-herpetic compounds.
Topics: Acyclovir; Animals; Antiviral Agents; Arabinonucleosides; Bromodeoxycytidine; Bromodeoxyuridine; Cell Line; Cytarabine; Deoxycytidine; Herpesviridae; Herpesviridae Infections; Idoxuridine; Macropodidae; Microbial Sensitivity Tests; Neutralization Tests; Thymidine; Trifluridine; Vidarabine | 1996 |
Relaxed enantioselectivity of human mitochondrial thymidine kinase and chemotherapeutic uses of L-nucleoside analogues.
Topics: Binding, Competitive; Bromodeoxyuridine; Cyclopentanes; Cytosol; Deoxycytidine; Deoxycytidine Kinase; Deoxyuridine; HeLa Cells; Humans; Mitochondria; Phosphorylation; Stereoisomerism; Substrate Specificity; Thymidine; Thymidine Kinase | 1997 |
Retroviral transduction of cancer cell lines with the gene encoding Drosophila melanogaster multisubstrate deoxyribonucleoside kinase.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antiviral Agents; Arabinonucleosides; Bromodeoxyuridine; Catalysis; Cell Division; Cell Nucleus; Cladribine; Cytarabine; Deoxycytidine; Drosophila melanogaster; Gemcitabine; Humans; Inhibitory Concentration 50; Kinetics; Osteosarcoma; Pancreatic Neoplasms; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Promoter Regions, Genetic; Retroviridae; Substrate Specificity; Thymidine; Thymidine Kinase; Transduction, Genetic; Tumor Cells, Cultured | 2000 |
Nucleoside analog cytotoxicity and bystander cell killing of cancer cells expressing Drosophila melanogaster deoxyribonucleoside kinase in the nucleus or cytosol.
Topics: Amino Acid Sequence; Animals; Arabinonucleosides; Bromodeoxyuridine; Cell Death; Cell Nucleus; Cytosol; Drosophila melanogaster; Gene Expression; Genes, Insect; Genetic Therapy; Green Fluorescent Proteins; Humans; Luminescent Proteins; Osteosarcoma; Phosphotransferases (Alcohol Group Acceptor); Point Mutation; Recombinant Fusion Proteins; Retroviridae; Thymidine; Transduction, Genetic; Tumor Cells, Cultured | 2001 |
Lipid-mediated protein delivery of suicide nucleoside kinases.
Topics: Animals; Arabinonucleosides; Bone Neoplasms; Bromodeoxyuridine; Cell Line, Tumor; CHO Cells; Cricetinae; Drosophila melanogaster; Endocytosis; Ganciclovir; Herpesvirus 1, Human; Humans; Liposomes; Osteosarcoma; Phosphatidylethanolamines; Phosphotransferases (Alcohol Group Acceptor); Recombinant Proteins; Thymidine; Thymidine Kinase | 2003 |
Bromovinyl-deoxyuridine: A selective substrate for mitochondrial thymidine kinase in cell extracts.
Topics: Arabinonucleosides; Biological Assay; Bromodeoxyuridine; Cell Extracts; Fibroblasts; Humans; Mitochondria; Phosphorylation; Protein Kinase Inhibitors; Substrate Specificity; Thymidine; Thymidine Kinase; Tumor Cells, Cultured | 2006 |
6-Azathymidine-4'-thionucleosides: synthesis and antiviral evaluation.
Topics: Acyclovir; Antiviral Agents; Bromodeoxyuridine; Ganciclovir; Magnetic Resonance Spectroscopy; Models, Molecular; Thionucleosides; Thymidine | 2008 |
5-Bromovinyl 2'-deoxyuridine phosphorylation by mitochondrial and cytosolic thymidine kinase (TK2 and TK1) and its use in selective measurement of TK2 activity in crude extracts.
Topics: Animals; Bromodeoxyuridine; Complex Mixtures; Cytosol; Enzyme Inhibitors; Humans; Mice; Mitochondria; Organ Specificity; Phosphorylation; Substrate Specificity; Thymidine; Thymidine Kinase; Thymidine Phosphorylase | 2008 |
Efficacy of lentivirus‑mediated Drosophila melanogaster deoxyribonucleoside kinase combined with (E)‑5‑(2‑bromovinyl)‑2'‑deoxyuridine or 1‑β‑D‑arabinofuranosylthymine therapy in human keloid fibroblasts.
Topics: Adult; Animals; Apoptosis; Arabinonucleosides; Bromodeoxyuridine; Bystander Effect; Cell Proliferation; Combined Modality Therapy; Drosophila melanogaster; Enzyme Assays; Female; Fibroblasts; Genes, Reporter; Genetic Vectors; Green Fluorescent Proteins; Humans; Insect Proteins; Keloid; Lentivirus; Male; Middle Aged; Phosphotransferases (Alcohol Group Acceptor); Primary Cell Culture; Thymidine; Transgenes | 2018 |
Engineered Thymidine-Active Deoxycytidine Kinase for Bystander Killing of Malignant Cells.
Topics: Animals; Apoptosis; Bromodeoxyuridine; Bystander Effect; Cell Line, Tumor; Deoxycytidine Kinase; Genes, Transgenic, Suicide; Genetic Therapy; HEK293 Cells; Humans; Male; Mice; Mice, SCID; Neoplasms; Prodrugs; Thymidine | 2019 |