thymidine has been researched along with alovudine in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (16.13) | 18.7374 |
| 1990's | 2 (6.45) | 18.2507 |
| 2000's | 10 (32.26) | 29.6817 |
| 2010's | 13 (41.94) | 24.3611 |
| 2020's | 1 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Baba, M; Balzarini, J; Broder, S; De Clercq, E; Herdewijn, P; Pauwels, R; Vanderhaeghe, H | 1 |
| Herdewijn, P; Munier-Lehmann, H; Pochet, S; Van Calenbergh, S; Van Rompaey, P; Vanheusden, V | 1 |
| Li, Y; Liotta, DC; Liu, L; Lutz, S; Soni, PB; Zhang, X | 1 |
| Wobus, AM | 1 |
| Camerman, A; Camerman, N; Mastropaolo, D | 1 |
| Langen, P; Lehmann, C; Matthes, E; Rosenthal, HA; Scholz, D | 1 |
| Durno, AG; Eckstein, F; Hartmann, H; Hirsch, MS; Hunsmann, G; Vogt, MW | 1 |
| Etzold, G; Kowollik, G; Langen, P; Reinert, H; Venner, H | 1 |
| Balzarini, J | 1 |
| Grierson, JR; Shields, AF | 1 |
| Borg, N; Stahle, L | 1 |
| Ha, HJ; Moon, DH; Oh, SJ; Ryu, JS; Yun, M | 1 |
| Shields, AF | 1 |
| Grierson, JR; Jordan, R; Krohn, KA; Schwartz, JL; Tamura, Y | 1 |
| Aboagye, EO; Kenny, LM; Price, PM | 1 |
| Krohn, KA; Link, JM; Mankoff, DA; Muzi, M; Spence, AM | 1 |
| Agarwal, HK; Parang, K | 1 |
| Eisenbarth, J; Eisenhut, M; Klein, PJ; Kruijer, PS; Oeser, T; Windhorst, AD | 1 |
| Eriksson, S; Sun, R; Wang, L | 1 |
| Cass, CE; Gati, WP; Graham, K; Jans, HS; McEwan, A; McQuarrie, S; Mercer, J; Paproski, RJ; Wuest, M; Young, JD | 1 |
| Emerick, LE; Krohn, KA; Plotnik, DA; Schwartz, JL; Unadkat, JD | 1 |
| Banerjee, D; Bertino, JR; Blasberg, RG; Cai, S; de Stanchina, E; Kochetkov, T; Moroz, MA; Nair, J; Schwartz, GK; Serganova, I; Shamis, M; Wu, J | 1 |
| Affolter, T; Buckman, D; Christensen, JG; Cullinane, C; Fahey, NR; Kuszpit, K; Lappin, PB; Li, W; Lira, ME; Nichols, T; O'Brien, P; Painter, CL; Spilker, M; Wong, A; Yan, Z; Zasadny, K; Zhang, CC; Zhang, Q | 1 |
| Bhattacharya, A; Manohar, K; Mittal, BR; Radotra, BD; Verma, GR | 1 |
| Ayers, GD; Coffey, RJ; Manning, HC; McKinley, ET; Saleh, SA; Smith, RA; Washington, MK; Zhao, P | 1 |
| Jang, SJ; Kim, SY; Lee, EJ; Lee, HJ; Lee, JJ; Lee, SJ; Moon, DH; Ryu, JS; Yeo, JS | 1 |
| Pauwels, P; Rapic, S; Staelens, S; Stroobants, S; Thomae, D; Van den Wyngaert, T; Vangestel, C; Verhaeghe, J | 1 |
| Aboagye, EO; Besret, L; Doblas, S; Griffiths, JR; Heinzmann, K; Heskamp, S; Honess, DJ; Jacobs, AH; Keen, H; Schelhaas, S; Smith, DM; Witney, TH | 1 |
| Aboagye, EO; Doblas, S; Döring, C; Faber, C; Fricke, IB; Griffiths, JR; Heinzmann, K; Heller, A; Hermann, S; Honess, DJ; Jacobs, AH; Just, N; Rieder, N; Schäfers, KP; Schelhaas, S; Schneider, R; Sinkus, R; Smith, DM; Wachsmuth, L | 1 |
| Albertella, M; Barghout, SH; Gronda, M; Hurren, R; Jeyaraju, DV; Jitkova, Y; Liyanage, SU; MacLean, N; Rizoska, B; Schimmer, AD; Siriwardena, TP; Targett-Adams, P; Wang, X; Yehudai, D | 1 |
| Kuge, Y; Matsuda, T; Nakajima, K; Ogawa, M; Suzuki, M; Yokouchi, Y | 1 |
3 review(s) available for thymidine and alovudine
| Article | Year |
|---|---|
Metabolism and mechanism of antiretroviral action of purine and pyrimidine derivatives.
Topics: Animals; Antiviral Agents; Dideoxyadenosine; Dideoxynucleosides; Humans; Lamivudine; Purines; Pyrimidines; Retroviridae; Spiro Compounds; Stavudine; Thymidine; Uridine; Zalcitabine; Zidovudine | 1994 |
Positron emission tomography imaging of cell proliferation in oncology.
Topics: Antiviral Agents; Cell Cycle; Cyclins; Dideoxynucleosides; DNA; Humans; Kinetics; Neoplasms; Phenotype; Thymidine; Tomography, Emission-Computed | 2004 |
True tracers: comparing FDG with glucose and FLT with thymidine.
Topics: Animals; Brain; Brain Mapping; Brain Neoplasms; Dideoxynucleosides; Fluorodeoxyglucose F18; Glucose; Humans; Image Interpretation, Computer-Assisted; Radionuclide Imaging; Radiopharmaceuticals; Thymidine | 2005 |
28 other study(ies) available for thymidine and alovudine
| Article | Year |
|---|---|
3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents.
Topics: Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Cytopathogenic Effect, Viral; Deoxyribonucleosides; HIV; Humans; Structure-Activity Relationship; T-Lymphocytes; Virus Replication | 1987 |
Thymidine and thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase.
Topics: Antitubercular Agents; Enzyme Inhibitors; Inhibitory Concentration 50; Kinetics; Mycobacterium tuberculosis; Nucleoside-Phosphate Kinase; Structure-Activity Relationship; Thymidine; Thymine Nucleotides | 2003 |
Synthesis of fluorescent nucleoside analogs as probes for 2'-deoxyribonucleoside kinases.
Topics: Animals; Drosophila melanogaster; Fluorescent Dyes; Nucleosides; Phosphotransferases (Alcohol Group Acceptor) | 2010 |
Clastogenic activity of cytosine arabinoside and 3'-deoxy-3'-fluorothymidine in Ehrlich ascites tumour cells in vitro.
Topics: Cell Line; Cell Survival; Chromosome Aberrations; Cytarabine; Dideoxynucleosides; Mitosis; Thymidine | 1976 |
Structure of the anti-human immunodeficiency virus agent 3'-fluoro-3'-deoxythymidine and electronic charge calculations for 3'-deoxythymidines.
Topics: Antiviral Agents; Dideoxynucleosides; HIV; Hydrogen Bonding; Molecular Conformation; Molecular Structure; Thymidine | 1990 |
Phosphorylation, anti-HIV activity and cytotoxicity of 3'-fluorothymidine.
Topics: Animals; Antiviral Agents; Cell Division; Cell Line; Cell Survival; Cytidine Diphosphate; Cytopathogenic Effect, Viral; Dideoxynucleosides; HIV; Humans; Mice; Phosphorylation; Rats; Thymidine; Virus Replication; Zidovudine | 1988 |
Enhanced in vitro inhibition of HIV-1 replication by 3'-fluoro-3'-deoxythymidine compared to several other nucleoside analogs.
Topics: Cell Line; Dideoxynucleosides; HIV-1; In Vitro Techniques; Leukocytes, Mononuclear; Microbial Sensitivity Tests; Structure-Activity Relationship; Thymidine; Virus Replication; Zidovudine | 1988 |
The phosphorylation of 3'-deoxy-3'-fluorothymidine and its incorporation into DNA in a cellfree system from tumor cells.
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell-Free System; Deoxyribonucleases; Dideoxynucleosides; DNA, Neoplasm; Fluorine; Micrococcus; Nucleotides; Phosphoric Diester Hydrolases; Phosphorus Isotopes; Spleen; Thymidine; Tritium | 1972 |
Radiosynthesis of 3'-deoxy-3'-[(18)F]fluorothymidine: [(18)F]FLT for imaging of cellular proliferation in vivo.
Topics: Cell Division; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Dideoxynucleosides; Fluorine Radioisotopes; Indicators and Reagents; Isotope Labeling; Molecular Conformation; Radiopharmaceuticals; Spectrophotometry, Ultraviolet; Thymidine; X-Ray Diffraction | 2000 |
Transport of alovudine (3'-fluorothymidine) into the brain and the cerebrospinal fluid of the rat, studied by microdialysis.
Topics: Acetazolamide; Animals; Anti-HIV Agents; Area Under Curve; Blood-Brain Barrier; Brain; Carbonic Anhydrase Inhibitors; Dideoxynucleosides; Drug Interactions; Infusions, Intravenous; Injections, Subcutaneous; Male; Microdialysis; Protein Binding; Rats; Rats, Sprague-Dawley; Thymidine | 2000 |
High radiochemical yield synthesis of 3'-deoxy-3'-[18F]fluorothymidine using (5'-O-dimethoxytrityl-2'-deoxy-3'-O-nosyl-beta-D-threo pentofuranosyl)thymine and its 3-N-BOC-protected analogue as a labeling precursor.
Topics: Dideoxynucleosides; Drug Stability; Formic Acid Esters; Isotope Labeling; Quality Control; Radiopharmaceuticals; Thymidine | 2003 |
PET imaging with 18F-FLT and thymidine analogs: promise and pitfalls.
Topics: Animals; Dideoxynucleosides; Fluorine Radioisotopes; Humans; Neoplasm Staging; Neoplasms; Radionuclide Imaging; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Thymidine | 2003 |
Monitoring tumor cell proliferation by targeting DNA synthetic processes with thymidine and thymidine analogs.
Topics: Animals; Arabinofuranosyluracil; Cell Division; Cell Line, Tumor; Dideoxynucleosides; DNA; Drug Delivery Systems; Humans; Metabolic Clearance Rate; Mice; Neoplasm Staging; Neoplasms; Radiopharmaceuticals; Thymidine; Thymidine Kinase; Tomography, Emission-Computed; Tritium | 2003 |
Application of solid-phase chemistry for the synthesis of 3'-fluoro-3'-deoxythymidine.
Topics: Anti-HIV Agents; Chemistry, Pharmaceutical; Dideoxynucleosides; Drug Design; Models, Chemical; Molecular Structure; Polymers; Thymidine; Trifluoroacetic Acid; Zidovudine | 2007 |
3'-Sulfonylesters of 2,5'-anhydro-1-(2-deoxy-beta-d-threo-pentofuranosyl)thymine as precursors for the synthesis of [(18)F]FLT: syntheses and radiofluorination trials.
Topics: Alkanesulfonates; Anhydrides; Dideoxynucleosides; Fluorine Radioisotopes; Isotope Labeling; Molecular Structure; Radiopharmaceuticals; Thymidine | 2008 |
Identification and characterization of mitochondrial factors modulating thymidine kinase 2 activity.
Topics: Animals; Chromatography, Gel; Deoxycytidine; Dideoxynucleosides; Enzyme Activation; Humans; Mitochondria; Phosphorylation; Rats; Recombinant Proteins; Thymidine; Thymidine Kinase; Zidovudine | 2010 |
Biodistribution and uptake of 3'-deoxy-3'-fluorothymidine in ENT1-knockout mice and in an ENT1-knockdown tumor model.
Topics: Animals; Biological Transport; Cell Line, Tumor; Cell Transformation, Neoplastic; Dideoxynucleosides; Equilibrative Nucleoside Transporter 1; Female; Gene Knockdown Techniques; Gene Knockout Techniques; Humans; Mice; Mice, Knockout; Neoplasms; Positron-Emission Tomography; RNA, Messenger; RNA, Small Interfering; Spleen; Thioinosine; Thymidine; Thymidine Kinase; Transfection | 2010 |
Different modes of transport for 3H-thymidine, 3H-FLT, and 3H-FMAU in proliferating and nonproliferating human tumor cells.
Topics: Arabinofuranosyluracil; Biological Transport; Cell Line, Tumor; Cell Proliferation; Dideoxynucleosides; Equilibrative Nucleoside Transport Proteins; Humans; Kinetics; Neoplasms; Positron-Emission Tomography; Thymidine; Tritium | 2010 |
Imaging colon cancer response following treatment with AZD1152: a preclinical analysis of [18F]fluoro-2-deoxyglucose and 3'-deoxy-3'-[18F]fluorothymidine imaging.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Colonic Neoplasms; Dideoxynucleosides; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Fluorouracil; HCT116 Cells; Humans; Immunoblotting; Ki-67 Antigen; Methotrexate; Mice; Mice, Nude; Organophosphates; Positron-Emission Tomography; Quinazolines; Radiopharmaceuticals; Thymidine; Thymidine Kinase; Xenograft Model Antitumor Assays | 2011 |
[(18)F]FLT-PET imaging does not always "light up" proliferating tumor cells.
Topics: Animals; Antineoplastic Agents; Bromodeoxyuridine; Cell Cycle Checkpoints; Cell Proliferation; Cyclin-Dependent Kinases; Dideoxynucleosides; Disease Models, Animal; Humans; Mice; Mice, Nude; Mice, SCID; Neoplasms; Piperazines; Positron-Emission Tomography; Pyridines; Thymidine; Xenograft Model Antitumor Assays | 2012 |
Intense FDG activity in a case of xanthogranulomatous cholecystitis without elevated fluorothymidine activity.
Topics: Cholecystitis; Dideoxynucleosides; Female; Fluorodeoxyglucose F18; Granuloma; Humans; Middle Aged; Multimodal Imaging; Positron-Emission Tomography; Thymidine; Tomography, X-Ray Computed; Xanthomatosis | 2013 |
Limits of [18F]-FLT PET as a biomarker of proliferation in oncology.
Topics: Animals; Biomarkers; Cell Line, Tumor; Cell Proliferation; Dideoxynucleosides; Disease Models, Animal; HCT116 Cells; Humans; Immunohistochemistry; Mice; Mutation; Neoplasms; Positron-Emission Tomography; Thymidine; Transplantation, Heterologous | 2013 |
Thymidine phosphorylase influences [(18)F]fluorothymidine uptake in cancer cells and patients with non-small cell lung cancer.
Topics: Adult; Aged; Biological Transport; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Dideoxynucleosides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Intracellular Space; Lung Neoplasms; Male; Middle Aged; Pyrrolidines; Thymidine; Thymidine Phosphorylase; Thymine; Time Factors | 2014 |
Evaluation of [
Topics: Adenosine Triphosphate; Animals; Biomarkers, Tumor; Cell Line, Tumor; Colorectal Neoplasms; Dideoxynucleosides; Disease Models, Animal; Female; Immunohistochemistry; Kinetics; Mice, Nude; Reproducibility of Results; Thymidine; Thymidine Kinase | 2017 |
3'-Deoxy-3'-[
Topics: Animals; Dideoxynucleosides; Humans; Mice; Neoplasms, Experimental; Thymidine; Thymidine Phosphorylase | 2018 |
Thymidine Metabolism as a Confounding Factor for 3'-Deoxy-3'-
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Artifacts; Biological Transport; Cell Transformation, Neoplastic; Colorectal Neoplasms; Dideoxynucleosides; Diffusion Magnetic Resonance Imaging; Female; Fluorouracil; HCT116 Cells; Humans; Leucovorin; Mice; Organoplatinum Compounds; Thymidine | 2018 |
The thymidine dideoxynucleoside analog, alovudine, inhibits the mitochondrial DNA polymerase γ, impairs oxidative phosphorylation and promotes monocytic differentiation in acute myeloid leukemia.
Topics: Animals; Antiviral Agents; Apoptosis; Cell Differentiation; Cell Proliferation; Dideoxynucleosides; DNA Polymerase gamma; Humans; Leukemia, Myeloid, Acute; Male; Mice; Mice, Inbred NOD; Mice, SCID; Mitochondria; Monocytes; Oxidative Phosphorylation; Thymidine; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2019 |
PD1 blockade alters cell-cycle distribution and affects 3'-deoxy-3'-[
Topics: Animals; Cell Division; Cell Line, Tumor; Dideoxynucleosides; Disease Models, Animal; Fluorodeoxyglucose F18; Glucose; Interferons; Interleukin-2; Mice; Receptors, Death Domain; Thymidine; Tumor Necrosis Factor-alpha | 2022 |