thymidine 5'-triphosphate has been researched along with zidovudine triphosphate in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.56) | 18.7374 |
| 1990's | 7 (38.89) | 18.2507 |
| 2000's | 9 (50.00) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boyle, N; Brooks, JL; Bruice, TW; Chen, F; Cook, PD; Fagan, P; Hurd, T; Jin, Y; Leeds, JM; Prhavc, M; Rajappan, V; Rajwanshi, VK; Wang, G | 1 |
| Boyle, NA; Brooks, JL; Bruice, TW; Chen, F; Cook, PD; Ewing, GJ; Fagan, P; Hurd, T; Leeds, JM; Prhavc, M; Rajwanshi, VK; Wang, G | 1 |
| Mellors, JW; Radzio, J; Sheen, CW; Sluis-Cremer, N; Zelina, S | 1 |
| Amblard, F; Bassit, L; Bondada, L; Coats, SJ; Detorio, M; Grier, J; Hernandez-Santiago, BI; Koontz, D; Mellors, JW; Rapp, KL; Schinazi, RF; Sluis-Cremer, N | 1 |
| Ilina, T; Myshakina, NS; Parniak, MA; Sirivolu, VR; Vernekar, SK; Wang, Z | 1 |
| Miller, WH; Reardon, JE | 1 |
| Buckheit, RW; Germany, JM; Parker, WB; Ross, LJ; Secrist, JA; Shaddix, SC; Shannon, WM; Vince, R; White, EL | 1 |
| Bazin, H; Chattopadhyaya, J; Eriksson, B; Oberg, B; Vrang, L | 1 |
| Clayton, DA; Eriksson, S; Xu, B | 1 |
| Lewis, W; Meyer, RR; Simpson, JF | 1 |
| Furman, PA; Haire, SE; Martin, JL; Painter, GR; Ray, PH; Wilson, JE; Wright, LL | 1 |
| Arzumanov, AA; Dyatkina, NB; Krayevsky, AA; Semizarov, DG; Victorova, LS | 1 |
| Amacker, M; Faraj, A; Gosselin, G; Hübscher, U; Imbach, JL; Maga, G; Mathé, C; Sommadossi, JP; Spadari, S | 1 |
| Maga, G; Pregnolato, M; Salvetti, R; Spadari, S; Ubiali, D | 1 |
| Ehresmann, B; Ehresmann, C; Lanchy, JM; Le Grice, SF; Marquet, R; Rigourd, M | 1 |
| Arissawa, M; Felcman, J; Herrera, JO | 1 |
| Guo, D; Jamburuthugoda, VK; Kim, B; Wedekind, JE | 1 |
| Agou, F; Biondi, R; Deville-Bonne, D; Guerreiro, C; Sarfati, R; Schneider, B; Veron, M | 1 |
18 other study(ies) available for thymidine 5'-triphosphate and zidovudine triphosphate
| Article | Year |
|---|---|
Synthesis of AZT 5'-triphosphate mimics and their inhibitory effects on HIV-1 reverse transcriptase.
Topics: Drug Stability; HIV Reverse Transcriptase; Humans; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Zidovudine | 2004 |
Synthesis of 2',3'-dideoxynucleoside 5'-alpha-P-borano-beta,gamma-(difluoromethylene)triphosphates and their inhibition of HIV-1 reverse transcriptase.
Topics: Animals; Anti-HIV Agents; Boron Compounds; Cattle; Deoxyribonucleotides; HIV Reverse Transcriptase; In Vitro Techniques; Reverse Transcriptase Inhibitors; Stereoisomerism | 2005 |
Mechanisms by which the G333D mutation in human immunodeficiency virus type 1 Reverse transcriptase facilitates dual resistance to zidovudine and lamivudine.
Topics: Anti-HIV Agents; Drug Resistance, Multiple, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Lamivudine; Models, Molecular; Mutation; Reverse Transcriptase Inhibitors; Thermodynamics; Zidovudine | 2008 |
Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides.
Topics: Anti-HIV Agents; Cell Line, Tumor; Cell Survival; Cells, Cultured; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Molecular Structure; Reverse Transcriptase Inhibitors | 2009 |
Clicking 3'-azidothymidine into novel potent inhibitors of human immunodeficiency virus.
Topics: Anti-HIV Agents; Cell Line, Tumor; Dose-Response Relationship, Drug; HIV; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Structure-Activity Relationship; Zidovudine | 2013 |
Human immunodeficiency virus reverse transcriptase. Substrate and inhibitor kinetics with thymidine 5'-triphosphate and 3'-azido-3'-deoxythymidine 5'-triphosphate.
Topics: Antiviral Agents; Base Sequence; Dideoxynucleotides; DNA, Viral; HIV-1; Kinetics; Molecular Sequence Data; Plasmids; Protein Binding; Recombinant Proteins; Restriction Mapping; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; RNA, Viral; Templates, Genetic; Thymine Nucleotides; Tritium; Zidovudine | 1990 |
Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase and human DNA polymerases alpha, beta, and gamma by the 5'-triphosphates of carbovir, 3'-azido-3'-deoxythymidine, 2',3'-dideoxyguanosine and 3'-deoxythymidine. A novel RN
Topics: Antiviral Agents; Base Sequence; Deoxyguanine Nucleotides; Dideoxynucleotides; DNA; DNA Polymerase I; DNA Polymerase II; DNA Polymerase III; HIV-1; Humans; In Vitro Techniques; Kinetics; Molecular Sequence Data; Reverse Transcriptase Inhibitors; RNA; Templates, Genetic; Thymine Nucleotides; Zidovudine | 1991 |
Different patterns of inhibition of avian myeloblastosis virus reverse transcriptase activity by 3'-azido-3'-deoxythymidine 5'-triphosphate and its threo isomer.
Topics: Avian Leukosis Virus; Avian Myeloblastosis Virus; Binding, Competitive; Dideoxynucleotides; Isomerism; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Viral Proteins; Zidovudine | 1987 |
Efficient incorporation of anti-HIV deoxynucleotides by recombinant yeast mitochondrial DNA polymerase.
Topics: Antiviral Agents; Base Sequence; Deoxyribonucleotides; Dideoxynucleotides; DNA-Directed DNA Polymerase; HIV; Mitochondria; Molecular Sequence Data; Recombinant Proteins; Saccharomyces cerevisiae; Substrate Specificity; Thymine Nucleotides; Zidovudine | 1995 |
Cardiac mitochondrial DNA polymerase-gamma is inhibited competitively and noncompetitively by phosphorylated zidovudine.
Topics: Animals; Cattle; Dideoxynucleotides; DNA Polymerase III; Kinetics; Mitochondria, Heart; Phosphorylation; Thymine Nucleotides; Zidovudine | 1994 |
Recombinant human immunodeficiency virus type 1 reverse transcriptase is heterogeneous.
Topics: Antiviral Agents; Chromatography, Affinity; Chromatography, Gel; Dideoxynucleotides; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Escherichia coli; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Protein Conformation; Protein Denaturation; Recombinant Fusion Proteins; RNA-Directed DNA Polymerase; Spectrometry, Fluorescence; Thymine Nucleotides; Urea; Zidovudine | 1996 |
Gamma-phosphate-substituted 2'-deoxynucleoside 5'-triphosphates as substrates for DNA polymerases.
Topics: Animals; Antiviral Agents; Dideoxynucleotides; DNA-Directed DNA Polymerase; Drug Stability; Humans; Phosphates; Substrate Specificity; Thymine Nucleotides; Zidovudine | 1996 |
Molecular basis for the enantioselectivity of HIV-1 reverse transcriptase: role of the 3'-hydroxyl group of the L-(beta)-ribose in chiral discrimination between D- and L-enantiomers of deoxy- and dideoxy-nucleoside triphosphate analogs.
Topics: Anti-HIV Agents; Carbohydrates; Catalysis; Deoxycytosine Nucleotides; Deoxyribonucleosides; Dideoxynucleosides; Dideoxynucleotides; DNA; Drug Resistance, Microbial; HIV Reverse Transcriptase; Humans; Hydroxyl Radical; Isoleucine; Kinetics; Nevirapine; Recombinant Fusion Proteins; Reverse Transcriptase Inhibitors; Ribose; Templates, Genetic; Thymine Nucleotides; Tyrosine; Zidovudine | 1999 |
Selective interaction of the human immunodeficiency virus type 1 reverse transcriptase nonnucleoside inhibitor efavirenz and its thio-substituted analog with different enzyme-substrate complexes.
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Binding, Competitive; Catalytic Domain; Cyclopropanes; Dideoxynucleotides; Drug Synergism; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Oxazines; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Zidovudine | 2000 |
Inhibition of the initiation of HIV-1 reverse transcription by 3'-azido-3'-deoxythymidine. Comparison with elongation.
Topics: Base Sequence; Dideoxynucleotides; Diphosphates; DNA Primers; HIV Reverse Transcriptase; HIV-1; Humans; Hydrolysis; Kinetics; Lymphocytes; Peptide Chain Elongation, Translational; Thymine Nucleotides; Transcription, Genetic; Zidovudine | 2000 |
Theoretical investigation of the triphosphate forms of azidothymidine and thymidine.
Topics: Dideoxynucleotides; Models, Theoretical; Stereoisomerism; Thymine Nucleotides; Zidovudine | 2003 |
Kinetic evidence for interaction of human immunodeficiency virus type 1 reverse transcriptase with the 3'-OH of the incoming dTTP substrate.
Topics: Acyclovir; Amino Acid Substitution; Asparagine; Dideoxynucleotides; Glutamine; HIV Reverse Transcriptase; Hydroxyl Radical; Isoleucine; Kinetics; Models, Molecular; Protein Binding; Substrate Specificity; Thymine Nucleotides; Valine; Zidovudine | 2005 |
The mechanism of phosphorylation of anti-HIV D4T by nucleoside diphosphate kinase.
Topics: Adenosine Triphosphate; Anti-HIV Agents; Dideoxynucleotides; HIV Reverse Transcriptase; Humans; Kinetics; Nucleoside-Diphosphate Kinase; Phosphorylation; Stavudine; Thymine Nucleotides; Zidovudine | 2000 |