Page last updated: 2024-08-24

thymidine 5'-triphosphate and uracil

thymidine 5'-triphosphate has been researched along with uracil in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's3 (23.08)18.2507
2000's3 (23.08)29.6817
2010's4 (30.77)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Focher, F; Mazzarello, P; Spadari, S; Verri, A; Verzeletti, S1
Beck, WR; Chang, JD; Isselbacher, EM; Nusbaum, NJ; Wright, GE1
Lasken, RS; Rashtchian, A; Schuster, DM1
Basnakian, AG; James, SJ; Melnyk, S; Miller, BJ; Pogribna, M; Pogribny, IP1
Allen, BG; Dornfeld, KJ; Johnson, M; Marsh, AE1
Iams, TA; McKee, EE; Morris, GW; Slepchenko, KG1
Saada, A1
Horváth, A; Vértessy, BG1
Grogan, BC; Guminski, AF; Parker, JB; Stivers, JT1
Anderson, DD; Quintero, CM; Stover, PJ1
Merényi, G; Szabó, JE; Takács, E; Tóth, J; Vértessy, BG1
Chabes, A; Hofer, A; Hombauer, H; Kolodziejczak, A; Luke, B; Reyes, GX; Schmidt, TT; Sharma, S; Wagner, T1
Huang, G; Li, W; Liu, H; Luo, S; Lv, X; Wang, Y; Zhou, D1

Other Studies

13 other study(ies) available for thymidine 5'-triphosphate and uracil

ArticleYear
Uracil in OriS of herpes simplex 1 alters its specific recognition by origin binding protein (OBP): does virus induced uracil-DNA glycosylase play a key role in viral reactivation and replication?
    Chromosoma, 1992, Volume: 102, Issue:1 Suppl

    Topics: Base Sequence; Cytosine; Deamination; Deoxyuracil Nucleotides; DNA Glycosylases; DNA Replication; DNA-Binding Proteins; Molecular Sequence Data; N-Glycosyl Hydrolases; Replicon; Simplexvirus; Thymine Nucleotides; Uracil; Uracil-DNA Glycosidase; Viral Proteins; Virus Activation; Virus Replication

1992
Enhancement of methotrexate cytotoxicity by uracil analogues that inhibit deoxyuridine triphosphate nucleotidohydrolase (dUTPase) activity.
    Advances in experimental medicine and biology, 1986, Volume: 195 Pt B

    Topics: Animals; Cattle; Cell Cycle; Cell Survival; Cells, Cultured; DNA; DNA Glycosylases; Humans; In Vitro Techniques; Methotrexate; Mice; N-Glycosyl Hydrolases; Pyrophosphatases; Thymine Nucleotides; Uracil; Uracil-DNA Glycosidase

1986
Archaebacterial DNA polymerases tightly bind uracil-containing DNA.
    The Journal of biological chemistry, 1996, Jul-26, Volume: 271, Issue:30

    Topics: Archaea; Base Composition; Base Sequence; Deoxyuracil Nucleotides; DNA-Directed DNA Polymerase; DNA, Bacterial; Dose-Response Relationship, Drug; Kinetics; Molecular Sequence Data; Nucleic Acid Synthesis Inhibitors; Oligonucleotides; Protein Binding; Thymine Nucleotides; Uracil

1996
Uracil misincorporation, DNA strand breaks, and gene amplification are associated with tumorigenic cell transformation in folate deficient/repleted Chinese hamster ovary cells.
    Cancer letters, 1999, Nov-01, Volume: 146, Issue:1

    Topics: Animals; Aspartic Acid; Cell Death; Cell Division; Cell Transformation, Neoplastic; CHO Cells; Cricetinae; DNA Damage; Folic Acid Deficiency; Gene Amplification; Mice; Mice, Inbred BALB C; Phosphonoacetic Acid; Thymine Nucleotides; Uracil

1999
Base excision repair of both uracil and oxidatively damaged bases contribute to thymidine deprivation-induced radiosensitization.
    International journal of radiation oncology, biology, physics, 2006, Aug-01, Volume: 65, Issue:5

    Topics: Aminopterin; Colony Count, Microbial; DNA Damage; DNA Repair; DNA Repair Enzymes; Endodeoxyribonucleases; Folic Acid Antagonists; Hydroxylamines; Mutation; Rad52 DNA Repair and Recombination Protein; Radiation Tolerance; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sulfanilamide; Sulfanilamides; Thymidine; Thymine Nucleotides; Uracil; Uracil-DNA Glycosidase

2006
Origin of pyrimidine deoxyribonucleotide pools in perfused rat heart: implications for 3'-azido-3'-deoxythymidine-dependent cardiotoxicity.
    The Biochemical journal, 2009, Aug-27, Volume: 422, Issue:3

    Topics: Animals; Chromatography, High Pressure Liquid; Cytidine; Cytidine Triphosphate; Deoxyadenine Nucleotides; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyuridine; Heart; In Vitro Techniques; Male; Perfusion; Phosphorylation; Pyrimidine Nucleotides; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Inhibitors; Thymine Nucleotides; Uracil; Uridine; Uridine Monophosphate; Uridine Triphosphate; Zidovudine

2009
Fishing in the (deoxyribonucleotide) pool.
    The Biochemical journal, 2009, Aug-27, Volume: 422, Issue:3

    Topics: Animals; Antimetabolites; Cytidine; Cytidine Triphosphate; Deoxyadenine Nucleotides; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyuridine; Heart; Humans; Mitochondria; Mitochondrial Diseases; Models, Biological; Phosphorylation; Pyrimidine Nucleotides; Rats; Thymine Nucleotides; Uracil; Uridine; Uridine Monophosphate; Uridine Triphosphate; Zidovudine

2009
A one-step method for quantitative determination of uracil in DNA by real-time PCR.
    Nucleic acids research, 2010, Volume: 38, Issue:21

    Topics: Animals; Cell Line; Deoxyuridine; DNA; DNA-Directed DNA Polymerase; DNA, Bacterial; Escherichia coli; Genome, Bacterial; Mice; Plasmids; Point Mutation; Polymerase Chain Reaction; Pyrococcus furiosus; Thymine Nucleotides; Uracil

2010
Effect of the thymidylate synthase inhibitors on dUTP and TTP pool levels and the activities of DNA repair glycosylases on uracil and 5-fluorouracil in DNA.
    Biochemistry, 2011, Feb-08, Volume: 50, Issue:5

    Topics: Animals; Cell Line; Chickens; Deoxyuracil Nucleotides; DNA; DNA Damage; DNA Glycosylases; DNA Repair; Enzyme Inhibitors; Fluorouracil; HeLa Cells; Humans; Kinetics; Mice; Thymidylate Synthase; Thymine Nucleotides; Uracil

2011
Identification of a de novo thymidylate biosynthesis pathway in mammalian mitochondria.
    Proceedings of the National Academy of Sciences of the United States of America, 2011, Sep-13, Volume: 108, Issue:37

    Topics: Amino Acid Sequence; Animals; Biosynthetic Pathways; CHO Cells; Cricetinae; Cricetulus; DNA, Mitochondrial; Gene Expression Regulation; Glycine; Humans; Mammals; Mitochondria; Molecular Sequence Data; Protein Transport; Sequence Alignment; Tetrahydrofolate Dehydrogenase; Thymidine Monophosphate; Thymidylate Synthase; Thymine Nucleotides; Uracil

2011
Trading in cooperativity for specificity to maintain uracil-free DNA.
    Scientific reports, 2016, Apr-11, Volume: 6

    Topics: Allosteric Regulation; Amino Acid Sequence; Binding Sites; Circular Dichroism; DNA; Humans; Kinetics; Magnesium; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleotide Deaminases; Protein Multimerization; Protein Structure, Quaternary; Protein Structure, Secondary; Pyrophosphatases; Sequence Alignment; Spectrometry, Fluorescence; Thymine Nucleotides; Uracil

2016
Inactivation of folylpolyglutamate synthetase Met7 results in genome instability driven by an increased dUTP/dTTP ratio.
    Nucleic acids research, 2020, 01-10, Volume: 48, Issue:1

    Topics: Cell Nucleus; Deoxyguanine Nucleotides; Deoxyuracil Nucleotides; DNA Damage; DNA, Fungal; Folic Acid; Gene Deletion; Gene Expression Regulation, Fungal; Genome, Fungal; Genomic Instability; Mitochondria; Mutation; Peptide Synthases; Saccharomyces cerevisiae; Thymine Nucleotides; Uracil

2020
Folic acid alleviates age-related cognitive decline and inhibits apoptosis of neurocytes in senescence-accelerated mouse prone 8: deoxythymidine triphosphate biosynthesis as a potential mechanism.
    The Journal of nutritional biochemistry, 2021, Volume: 97

    Topics: Aging; Animals; Apoptosis; Brain; Cognitive Dysfunction; Dietary Supplements; Folic Acid; Male; Memory; Mice; Morris Water Maze Test; Neurons; Quinazolines; Telomere Shortening; Thiophenes; Thymidylate Synthase; Thymine Nucleotides; Uracil

2021