thymidine 5'-triphosphate has been researched along with raltitrexed in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aherne, GW; Boyle, FT; Brown, M; Gibson, W; Hardcastle, A; Jackman, AL; Kelland, LR; Kimbell, R | 1 |
| Aherne, W; Boyle, FT; Hardcastle, A; Jackman, AL; Kimbell, R | 1 |
| Aherne, GW; Hardcastle, A; Jackman, AL; Raynaud, F | 1 |
| Horowitz, RW; Ladner, RD; Schwartz, EL; Wadler, S; Zhang, H | 1 |
| Furusho, K; Kubota, M; Wakazono, Y | 1 |
| Andis, SL; Bewley, JR; Chen, VJ; Iversen, PW; Mendelsohn, LG; Schultz, RM; Seitz, DE; Shih, C; Tonkinson, JL | 1 |
| Huang, G; Li, W; Liu, H; Luo, S; Lv, X; Wang, Y; Zhou, D | 1 |
| Barat, C; Breton, Y; Desrosiers, V; Ouellet, M; Tremblay, MJ | 1 |
8 other study(ies) available for thymidine 5'-triphosphate and raltitrexed
| Article | Year |
|---|---|
Mechanisms of acquired resistance to the quinazoline thymidylate synthase inhibitor ZD1694 (Tomudex) in one mouse and three human cell lines.
Topics: Animals; Antineoplastic Agents; Carrier Proteins; Deoxyuracil Nucleotides; Drug Resistance; Female; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Antagonists; Humans; Kinetics; Leukemia L1210; Lymphocytes; Methotrexate; Mice; Neoplasm Proteins; Ovarian Neoplasms; Peptide Synthases; Polyglutamic Acid; Proteins; Quinazolines; Receptors, Cell Surface; Thiophenes; Thymidylate Synthase; Thymine Nucleotides; Tumor Cells, Cultured | 1995 |
The duration of the inhibition of thymidylate synthase in intact L1210 cells exposed to two different classes of quinazoline analogues.
Topics: Animals; Antineoplastic Agents; Cell Division; Deoxyuracil Nucleotides; Drug Screening Assays, Antitumor; Folic Acid; Folic Acid Antagonists; Leukemia L1210; Mice; Quinazolines; Structure-Activity Relationship; Thiophenes; Thymidylate Synthase; Thymine Nucleotides | 1993 |
Immunoreactive dUMP and TTP pools as an index of thymidylate synthase inhibition; effect of tomudex (ZD1694) and a nonpolyglutamated quinazoline antifolate (CB30900) in L1210 mouse leukaemia cells.
Topics: Animals; Deoxyuracil Nucleotides; Dipeptides; Dose-Response Relationship, Drug; Folic Acid Antagonists; Leukemia, Experimental; Mice; Mice, Inbred Strains; Quinazolines; Radioimmunoassay; Thiophenes; Thymidylate Synthase; Thymine Nucleotides; Tumor Cells, Cultured | 1996 |
Measurement of deoxyuridine triphosphate and thymidine triphosphate in the extracts of thymidylate synthase-inhibited cells using a modified DNA polymerase assay.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Colonic Neoplasms; Deoxyuracil Nucleotides; DNA-Directed DNA Polymerase; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Kinetics; Pyrophosphatases; Quinazolines; Templates, Genetic; Thiophenes; Thymidylate Synthase; Thymine Nucleotides; Tumor Cells, Cultured | 1997 |
Increased cell killing and mutagenecity by DNA alkylating agents in cells with decreased TTP pools.
Topics: Alkylating Agents; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethyl Methanesulfonate; HL-60 Cells; Humans; Hypoxanthine Phosphoribosyltransferase; Kinetics; Methylnitronitrosoguanidine; Mutagens; Quinazolines; Thiophenes; Thymidylate Synthase; Thymine Nucleotides | 1998 |
Cellular pharmacology of MTA: a correlation of MTA-induced cellular toxicity and in vitro enzyme inhibition with its effect on intracellular folate and nucleoside triphosphate pools in CCRF-CEM cells.
Topics: Acid Anhydride Hydrolases; Antimetabolites, Antineoplastic; Deoxyribonucleotides; Enzyme Inhibitors; Folic Acid; Folic Acid Antagonists; Glutamates; Guanine; Humans; Methotrexate; Nucleoside-Diphosphate Kinase; Nucleoside-Triphosphatase; Pemetrexed; Quinazolines; Ribonucleotides; Tetrahydrofolates; Thiophenes; Thymidylate Synthase; Thymine Nucleotides; Tumor Cells, Cultured | 1999 |
Folic acid alleviates age-related cognitive decline and inhibits apoptosis of neurocytes in senescence-accelerated mouse prone 8: deoxythymidine triphosphate biosynthesis as a potential mechanism.
Topics: Aging; Animals; Apoptosis; Brain; Cognitive Dysfunction; Dietary Supplements; Folic Acid; Male; Memory; Mice; Morris Water Maze Test; Neurons; Quinazolines; Telomere Shortening; Thiophenes; Thymidylate Synthase; Thymine Nucleotides; Uracil | 2021 |
Thymidylate synthase is essential for efficient HIV-1 replication in macrophages.
Topics: Cells, Cultured; Enzyme Inhibitors; HIV-1; Humans; Macrophages; Quinazolines; RNA Interference; RNA, Small Interfering; SAM Domain and HD Domain-Containing Protein 1; Thiophenes; Thymidylate Synthase; Thymine Nucleotides; Virus Replication | 2021 |