thymidine 5'-triphosphate has been researched along with hydroxyurea in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (61.29) | 18.7374 |
| 1990's | 9 (29.03) | 18.2507 |
| 2000's | 3 (9.68) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Daikoku, T; Maeno, K; Nishiyama, Y; Yamamoto, N | 1 |
| Fager, RS; Plucinski, TM; Reddy, GP | 1 |
| Höglund, L; Pontis, E; Reichard, P | 1 |
| Chubb, S; Grindey, GB; Heinemann, V; Hertel, LW; Plunkett, W; Sen, A; Xu, YZ | 1 |
| Schroeder, AL; Srivastava, VK | 1 |
| Akiyama, Y; Kiriyama, Y; Kitoh, T; Kubota, M; Mikawa, H; Takimoto, T; Tanizawa, A | 1 |
| Heinemann, V; Plunkett, W | 1 |
| Cheng, YC; Grill, SP; Nutter, LM | 2 |
| Barlow, T | 1 |
| Eriksson, S; Skog, S; Tribukait, B; Wallström, B | 1 |
| Bianchi, V; Pontis, E; Reichard, P | 2 |
| Lagergren, J; Reichard, P | 1 |
| Katz, EJ; Sirover, MA | 1 |
| Fox, RM | 1 |
| Nicander, B; Reichard, P | 1 |
| Malick, NC; Snyder, RD | 1 |
| Kasper, LH; Pfefferkorn, ER | 1 |
| Tyrsted, G | 1 |
| Hanaoka, F; Kato, H; Yamada, K; Yamada, M | 1 |
| Snyder, RD | 1 |
| Cory, JG; Sato, A | 1 |
| Frels, JS; Jahn, CL | 1 |
| Ahluwalia, GS; Gao, WY; Johns, DG; Mitsuya, H | 1 |
| Bianchi, LC; Bianchi, V; Borella, S; Calderazzo, F; D'Agaro, P; Giacca, M; Rampazzo, C; Reichard, P | 1 |
| Cox, S; Palmer, S | 1 |
| Berkenblit, R; Damle, S; Haynes, H; Kaleya, R; Ladner, RD; Murgo, A; Schechner, R; Wadler, S | 1 |
| Chimploy, K; Mathews, CK; Tassotto, ML | 1 |
| Fagny, C; Robberecht, P; Svoboda, M; Vandevelde, M | 1 |
| Bianchi, V; Crovatto, K; Fabris, S; Frangini, M; Franzolin, E; Rampazzo, C | 1 |
1 review(s) available for thymidine 5'-triphosphate and hydroxyurea
| Article | Year |
|---|---|
Changes in deoxynucleoside triphosphate pools induced by inhibitors and modulators of ribonucleotide reductase.
Topics: Animals; Aziridines; Cells, Cultured; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; Humans; Hydroxyurea; Ribonucleotide Reductases; Substrate Specificity; T-Lymphocytes; Thiosemicarbazones; Thymine Nucleotides | 1985 |
1 trial(s) available for thymidine 5'-triphosphate and hydroxyurea
| Article | Year |
|---|---|
Phase II/pharmacodynamic trial of dose-intensive, weekly parenteral hydroxyurea and fluorouracil administered with interferon alfa-2a in patients with refractory malignancies of the gastrointestinal tract.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Deoxyuracil Nucleotides; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Humans; Hydroxyurea; Interferon alpha-2; Interferon-alpha; Leukocytes, Mononuclear; Male; Middle Aged; Pancreatic Neoplasms; Prospective Studies; Recombinant Proteins; Stomach Neoplasms; Thymine Nucleotides; Treatment Outcome | 1999 |
29 other study(ies) available for thymidine 5'-triphosphate and hydroxyurea
| Article | Year |
|---|---|
Role of viral ribonucleotide reductase in the increase of dTTP pool size in herpes simplex virus-infected Vero cells.
Topics: Animals; Chromosome Deletion; Floxuridine; Hydroxyurea; Kinetics; Phosphorylation; Ribonucleotide Reductases; Simplexvirus; Thymidine; Thymine Nucleotides; Vero Cells; Virus Replication | 1991 |
Allosteric interaction of components of the replitase complex is responsible for enzyme cross-inhibition.
Topics: Allosteric Regulation; Animals; Aphidicolin; Batroxobin; Cricetinae; Deoxyribonucleosides; Diterpenes; DNA; Hydroxyurea; Interphase; Nucleic Acid Synthesis Inhibitors; Ribonucleotide Reductases; RNA; Serine Proteinase Inhibitors; Thymidine Kinase; Thymidylate Synthase; Thymine Nucleotides | 1990 |
Deoxyribonucleotide metabolism in hydroxyurea-resistant V79 hamster cells.
Topics: Animals; Cell Line; Cricetinae; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA; Drug Resistance; Hydroxyurea; Thymine Nucleotides | 1991 |
Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2',2'-difluorodeoxycytidine.
Topics: Cell Line; Cytidine; Deoxycytidine; Deoxycytosine Nucleotides; DNA; Gemcitabine; Humans; Hydroxyurea; Oxidation-Reduction; Ribonucleoside Diphosphate Reductase; Ribonucleotides; Thymine Nucleotides | 1990 |
Deoxyribonucleoside triphosphate pools in mutagen sensitive mutants of Neurospora crassa.
Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA, Fungal; Genes, Fungal; Histidine; Hydroxyurea; Mutation; Neurospora; Neurospora crassa; Thymine Nucleotides | 1989 |
Ara-CTP metabolism following hydroxyurea or methotrexate treatment in human leukemia cell lines.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Deoxycytidine; Deoxycytosine Nucleotides; Drug Synergism; Humans; Hydroxyurea; Leukemia; Leukemia, Promyelocytic, Acute; Methotrexate; Thymine Nucleotides; Tumor Cells, Cultured | 1989 |
Modulation of deoxynucleotide metabolism by the deoxycytidylate deaminase inhibitor 3,4,5,6-tetrahydrodeoxyuridine.
Topics: Cell Line; Cytarabine; Cytidine Diphosphate; DCMP Deaminase; Deoxycytidine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; Deoxyuridine; Hydroxyurea; Kinetics; Nucleotide Deaminases; Ribonucleotide Reductases; T-Lymphocytes; Tetrahydrouridine; Thymine Nucleotides | 1989 |
Can ribonucleotide reductase be considered as an effective target for developing antiherpes simplex virus type II (HSV-2) compounds?
Topics: Antiviral Agents; Cytidine; Deoxyguanine Nucleotides; DNA, Viral; HeLa Cells; Humans; Hydroxyurea; Phosphates; Ribonucleotide Reductases; Simplexvirus; Thymine Nucleotides | 1985 |
The sources of thymidine nucleotides for virus DNA synthesis in herpes simplex virus type 2-infected cells.
Topics: Animals; Cell Line; Chlorocebus aethiops; DNA; DNA, Viral; HeLa Cells; Humans; Hydroxyurea; Kidney; Ribonucleotide Reductases; Simplexvirus; Thymidine; Thymine Nucleotides | 1985 |
Evidence for a new ribonucleotide reductase in anaerobic E. coli.
Topics: Anaerobiosis; Antibodies, Monoclonal; Escherichia coli; Guanosine Triphosphate; Hydroxyurea; Ribonucleotide Reductases; Thymine Nucleotides | 1988 |
Deoxyribonucleoside triphosphate metabolism and the mammalian cell cycle. Effects of hydroxyurea on mutant and wild-type mouse S49 T-lymphoma cells.
Topics: Animals; Cell Cycle; Cell Line; Deoxyadenine Nucleotides; Deoxycytidine Kinase; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; Hydroxyurea; Lymphoma; Mice; Mutation; Purine-Nucleoside Phosphorylase; Ribonucleotide Reductases; T-Lymphocytes; Thymidine Kinase; Thymine Nucleotides | 1987 |
Interrelations between substrate cycles and de novo synthesis of pyrimidine deoxyribonucleoside triphosphates in 3T6 cells.
Topics: Animals; Cell Cycle; Cell Line; Deoxycytosine Nucleotides; Deoxyribonucleosides; Deoxyuracil Nucleotides; Dipyridamole; DNA Replication; Fibroblasts; Hydroxyurea; Mice; Phosphorylation; Thymidine Monophosphate; Thymine Nucleotides | 1986 |
Purine deoxyribonucleosides counteract effects of hydroxyurea on deoxyribonucleoside triphosphate pools and DNA synthesis.
Topics: Animals; Cell Line; Cricetinae; Deoxyadenine Nucleotides; Deoxyadenosines; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyguanosine; DNA; Hydroxyurea; Nucleotides; Purine Nucleosides; Thymine Nucleotides | 1987 |
Changes of deoxyribonucleoside triphosphate pools induced by hydroxyurea and their relation to DNA synthesis.
Topics: Cells, Cultured; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA; Hydroxyurea; Ribonucleotide Reductases; Thymine Nucleotides | 1986 |
DNA nucleotide excision-repair synthesis is independent of perturbations of deoxynucleoside triphosphate pool size.
Topics: Cells, Cultured; Deoxyribonucleotides; DNA; DNA Repair; Humans; Hydroxyurea; Thymine Nucleotides; Ultraviolet Rays | 1987 |
Relations between synthesis of deoxyribonucleotides and DNA replication in 3T6 fibroblasts.
Topics: Animals; Aphidicolin; Deoxycytidine; Deoxyribonucleotides; Diterpenes; DNA Replication; Fibroblasts; Hydroxyurea; Mice; Thymidine; Thymidylate Synthase; Thymine Nucleotides | 1985 |
Effects of hydroxyurea and thymidine derivatives on the uptake and metabolism of deoxycytidine and arabinofuranosylcytosine in log phase and contact-inhibited human diploid fibroblasts.
Topics: Arabinofuranosylcytosine Triphosphate; Cells, Cultured; Cytarabine; Deamination; Deoxycytidine; Deoxyuracil Nucleotides; Fibroblasts; Humans; Hydroxyurea; Thymidine; Thymine Nucleotides; Tritium | 1985 |
Hydroxyurea inhibition of growth and DNA synthesis in Toxoplasma gondii: characterization of a resistant mutant.
Topics: Animals; Cells, Cultured; Deoxycytosine Nucleotides; DNA; Drug Resistance; Fibroblasts; Humans; Hydroxyurea; Mutation; Ribonucleotide Reductases; RNA; Thymine Nucleotides; Toxoplasma | 1982 |
Effect of hydroxyurea and 5-fluorodeoxyuridine on deoxyribonucleoside triphosphate pools early in phytohemagglutinin-stimulated human lymphocytes.
Topics: Deoxyribonucleotides; DNA; Floxuridine; Humans; Hydroxyurea; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Thymine Nucleotides | 1982 |
Effects of inhibitors on repair DNA synthesis in in vitro systems.
Topics: Antimetabolites; Cytarabine; Deoxyribonucleotides; DNA Repair; DNA Replication; HeLa Cells; Humans; Hydroxyurea; Interphase; Kinetics; Thymine Nucleotides; Ultraviolet Rays | 1984 |
Deoxyribonucleoside triphosphate pools in human diploid fibroblasts and their modulation by hydroxyurea and deoxynucleosides.
Topics: Cells, Cultured; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleosides; Deoxyribonucleotides; Diploidy; Fibroblasts; Humans; Hydroxyurea; Thymine Nucleotides | 1984 |
Evaluation of combinations of drugs that inhibit Ehrlich tumor cell ribonucleotide reductase.
Topics: Aldehydes; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; Drug Interactions; Drug Synergism; Edetic Acid; Hydroxyurea; Imidazoles; Inosine; Isoquinolines; Mice; Pyrazoles; Ribonucleotide Reductases; Thiosemicarbazones; Thymine Nucleotides | 1981 |
DNA rearrangements in Euplotes crassus coincide with discrete periods of DNA replication during the polytene chromosome stage of macronuclear development.
Topics: Animals; Base Sequence; Chromosomes; Crosses, Genetic; DNA Replication; DNA Transposable Elements; DNA, Protozoan; Euplotes; Hydroxyurea; Polymerase Chain Reaction; Species Specificity; Thymidine; Thymine Nucleotides | 1995 |
2',3'-Didehydro-3'-deoxythymidine: regulation of its metabolic activation by modulators of thymidine-5'-triphosphate biosynthesis.
Topics: Amides; Biotransformation; Biphenyl Compounds; Cell Line; Deoxyguanosine; Floxuridine; HIV; HIV Reverse Transcriptase; HIV-1; Humans; Hydroxyurea; Kinetics; Methotrexate; Models, Biological; Phosphorylation; Pyrazoles; Reverse Transcriptase Inhibitors; Ribonucleosides; Ribose; RNA-Directed DNA Polymerase; Stavudine; Thymidine Kinase; Thymine Nucleotides; Tumor Cells, Cultured | 1996 |
Synergistic antiviral action of ribonucleotide reductase inhibitors and 3'-azido-3'-deoxythymidine on HIV type 1 infection in vitro.
Topics: Antiviral Agents; Cell Cycle; Cytidine; Drug Synergism; Enzyme Inhibitors; HIV Core Protein p24; HIV-1; Humans; Hydroxyurea; Leukocytes, Mononuclear; Phosphorylation; Reverse Transcriptase Inhibitors; Ribonucleotide Reductases; Thymine Nucleotides; Tumor Cells, Cultured; Virus Replication; Zidovudine | 1996 |
Increased activation of the combination of 3'-azido-3'-deoxythymidine and 2'-deoxy-3'-thiacytidine in the presence of hydroxyurea.
Topics: Anti-HIV Agents; Cell Line; Deoxycytosine Nucleotides; Drug Synergism; Hydroxyurea; Lamivudine; Phosphorylation; Thymine Nucleotides; Zidovudine | 1997 |
Ribonucleotide reductase, a possible agent in deoxyribonucleotide pool asymmetries induced by hypoxia.
Topics: Animals; Cells, Cultured; Cricetinae; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; Hydrogen-Ion Concentration; Hydroxyurea; Hypoxia; Mice; Models, Chemical; Nucleic Acid Synthesis Inhibitors; Oxygen; Recombinant Proteins; Ribonucleotide Reductases; Thymine Nucleotides; Time Factors | 2000 |
Ribonucleotide reductase and thymidine phosphorylation: two potential targets of azodicarbonamide.
Topics: Animals; Antineoplastic Agents; Azo Compounds; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Drug Interactions; Hydroxyurea; Immunosuppressive Agents; Methotrexate; Phosphorylation; Ribonucleotide Reductases; Thymidine; Thymine Nucleotides; Tumor Cells, Cultured | 2002 |
Mitochondrial thymidine kinase and the enzymatic network regulating thymidine triphosphate pools in cultured human cells.
Topics: Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Cytoplasm; Cytosol; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Hydroxyurea; Mitochondria; Models, Biological; Models, Genetic; RNA Interference; Thymidine Kinase; Thymine Nucleotides | 2007 |