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thymidine 5'-triphosphate and folic acid

thymidine 5'-triphosphate has been researched along with folic acid in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.88)18.7374
1990's9 (52.94)18.2507
2000's2 (11.76)29.6817
2010's3 (17.65)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Kwok, JB; Tattersall, MH1
Brumley, J; Hayman, RJ; Rose, IS; van der Weyden, MB1
Erbe, RW; Wang, JC1
Aherne, GW; Boyle, FT; Brown, M; Gibson, W; Hardcastle, A; Jackman, AL; Kelland, LR; Kimbell, R1
Aherne, W; Boyle, FT; Hardcastle, A; Jackman, AL; Kimbell, R1
Allen, RH; Chandler, CJ; Halsted, CH; James, SJ; Muskhelishvili, L; Poirier, L; Stabler, SP; Villanueva, J1
Jackson, CD; James, SJ; Miller, BJ; Weis, C1
Gretz, DM; Henning, SM; Jacob, RA; James, SJ; Miller, BJ; Pogribny, IP; Swendseid, ME; Taylor, PC1
Bewley, J; Chen, VJ; Gates, SB; Habeck, LL; Mendelsohn, LG; Ray, J; Shackelford, KA; Tonkinson, JL; Toth, JE1
Andis, SL; Bewley, JR; Chen, VJ; Iversen, PW; Mendelsohn, LG; Schultz, RM; Seitz, DE; Shih, C; Tonkinson, JL1
Deng, L; Knock, E; Lawrance, AK; Rozen, R; Wang, XL; Wu, Q1
Deng, L; Lawrance, AK; Rozen, R1
Lin, DM; Macfarlane, AJ; McEntee, MF; Perry, CA; Stover, PJ1
Cabezas-Herrera, J; Chazarra, S; Fernández-Pérez, MP; Montenegro, MF; Piñero-Madrona, A; Rodríguez-López, JN; Sáez-Ayala, M; Sánchez-del-Campo, L1
Ducker, GS; Gitai, Z; Li, SH; Mayer, JA; Morscher, RJ; Rabinowitz, JD; Sperl, W1
Chabes, A; Hofer, A; Hombauer, H; Kolodziejczak, A; Luke, B; Reyes, GX; Schmidt, TT; Sharma, S; Wagner, T1
Huang, G; Li, W; Liu, H; Luo, S; Lv, X; Wang, Y; Zhou, D1

Other Studies

17 other study(ies) available for thymidine 5'-triphosphate and folic acid

ArticleYear
Inhibition of 2-desamino-2-methyl-10-propagyl-5,8-dideazafolic acid cytotoxicity by 5,10-dideazatetrahydrofolate in L1210 cells with decrease in DNA fragmentation and deoxyadenosine triphosphate pools.
    Biochemical pharmacology, 1991, Jul-15, Volume: 42, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Survival; Deoxyadenine Nucleotides; DNA, Neoplasm; Drug Antagonism; Folic Acid; Folic Acid Antagonists; Hypoxanthine; Hypoxanthines; Leukemia L1210; Mice; Tetrahydrofolates; Thymine Nucleotides; Tumor Cells, Cultured

1991
Folate-deficient human lymphoblasts: changes in deoxynucleotide metabolism and thymidylate cycle activities.
    European journal of haematology, 1991, Volume: 47, Issue:2

    Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyuridine; Dose-Response Relationship, Drug; Folic Acid; Folic Acid Deficiency; Humans; Lymphocyte Activation; Lymphocytes; Nucleotides; Thymidine; Thymidylate Synthase; Thymine Nucleotides

1991
Thymidylate metabolism in fragile X syndrome cells.
    Somatic cell and molecular genetics, 1985, Volume: 11, Issue:4

    Topics: Aneuploidy; Cell Line; Deoxyribonucleotides; Female; Folic Acid; Folic Acid Antagonists; Fragile X Syndrome; Heterozygote; Humans; Lymphocytes; Male; Ribonucleotide Reductases; Sex Chromosome Aberrations; Thymidine Monophosphate; Thymidylate Synthase; Thymine Nucleotides

1985
Mechanisms of acquired resistance to the quinazoline thymidylate synthase inhibitor ZD1694 (Tomudex) in one mouse and three human cell lines.
    British journal of cancer, 1995, Volume: 71, Issue:5

    Topics: Animals; Antineoplastic Agents; Carrier Proteins; Deoxyuracil Nucleotides; Drug Resistance; Female; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Antagonists; Humans; Kinetics; Leukemia L1210; Lymphocytes; Methotrexate; Mice; Neoplasm Proteins; Ovarian Neoplasms; Peptide Synthases; Polyglutamic Acid; Proteins; Quinazolines; Receptors, Cell Surface; Thiophenes; Thymidylate Synthase; Thymine Nucleotides; Tumor Cells, Cultured

1995
The duration of the inhibition of thymidylate synthase in intact L1210 cells exposed to two different classes of quinazoline analogues.
    Advances in experimental medicine and biology, 1993, Volume: 338

    Topics: Animals; Antineoplastic Agents; Cell Division; Deoxyuracil Nucleotides; Drug Screening Assays, Antitumor; Folic Acid; Folic Acid Antagonists; Leukemia L1210; Mice; Quinazolines; Structure-Activity Relationship; Thiophenes; Thymidylate Synthase; Thymine Nucleotides

1993
Ethanol feeding of micropigs alters methionine metabolism and increases hepatocellular apoptosis and proliferation.
    Hepatology (Baltimore, Md.), 1996, Volume: 23, Issue:3

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Administration, Oral; Analysis of Variance; Animal Feed; Animals; Apoptosis; Cell Division; Deoxyuracil Nucleotides; Ethanol; Folic Acid; Homocysteine; Liver; Male; Methionine; Proliferating Cell Nuclear Antigen; S-Adenosylhomocysteine; S-Adenosylmethionine; Swine; Swine, Miniature; Thymine Nucleotides

1996
Dietary nucleotides: effects on cell proliferation following partial hepatectomy in rats fed NIH-31, AIN-76A, or folate/methyl-deficient diets.
    The Journal of nutrition, 1997, Volume: 127, Issue:5 Suppl

    Topics: Animal Feed; Animals; Cell Division; Deoxyribonucleotides; Deoxyuracil Nucleotides; Diet; Folic Acid; Folic Acid Deficiency; Food, Formulated; Hepatectomy; Male; Rats; Rats, Inbred F344; Thymine Nucleotides; Weaning

1997
Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women.
    The Journal of nutrition, 1998, Volume: 128, Issue:7

    Topics: Creatinine; Deoxyuracil Nucleotides; Diet; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Lymphocytes; Malondialdehyde; Middle Aged; Mitogens; Nutritional Requirements; Postmenopause; Thymine Nucleotides; Vitamin B 12

1998
The antiproliferative and cell cycle effects of 5,6,7, 8-tetrahydro-N5,N10-carbonylfolic acid, an inhibitor of methylenetetrahydrofolate dehydrogenase, are potentiated by hypoxanthine.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Division; Deoxyadenine Nucleotides; Drug Synergism; Enzyme Inhibitors; Folic Acid; Humans; Hypoxanthine; Methylenetetrahydrofolate Dehydrogenase (NADP); Thymine Nucleotides; Tumor Cells, Cultured

1998
Cellular pharmacology of MTA: a correlation of MTA-induced cellular toxicity and in vitro enzyme inhibition with its effect on intracellular folate and nucleoside triphosphate pools in CCRF-CEM cells.
    Seminars in oncology, 1999, Volume: 26, Issue:2 Suppl 6

    Topics: Acid Anhydride Hydrolases; Antimetabolites, Antineoplastic; Deoxyribonucleotides; Enzyme Inhibitors; Folic Acid; Folic Acid Antagonists; Glutamates; Guanine; Humans; Methotrexate; Nucleoside-Diphosphate Kinase; Nucleoside-Triphosphatase; Pemetrexed; Quinazolines; Ribonucleotides; Tetrahydrofolates; Thiophenes; Thymidylate Synthase; Thymine Nucleotides; Tumor Cells, Cultured

1999
Strain differences in mice highlight the role of DNA damage in neoplasia induced by low dietary folate.
    The Journal of nutrition, 2008, Volume: 138, Issue:4

    Topics: Animals; Betaine; Diet; DNA Damage; DNA Methylation; Female; Folic Acid; Folic Acid Deficiency; Gastrointestinal Neoplasms; Gene Expression Regulation, Neoplastic; Genotype; Homocysteine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; RNA, Messenger; Thymine Nucleotides; Uridine Triphosphate

2008
Methylenetetrahydrofolate reductase deficiency and low dietary folate reduce tumorigenesis in Apc min/+ mice.
    Gut, 2009, Volume: 58, Issue:6

    Topics: Adenoma; Adenomatous Polyposis Coli Protein; Animals; Apoptosis; Colorectal Neoplasms; Diet; DNA Methylation; Female; Folic Acid; Genetic Predisposition to Disease; Genotype; Homocysteine; Male; Methylenetetrahydrofolate Reductase (NADPH2); Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Pregnancy; Prenatal Nutritional Physiological Phenomena; Random Allocation; Thymine Nucleotides; Uridine Triphosphate; Weaning

2009
Shmt1 heterozygosity impairs folate-dependent thymidylate synthesis capacity and modifies risk of Apc(min)-mediated intestinal cancer risk.
    Cancer research, 2011, Mar-15, Volume: 71, Issue:6

    Topics: Adenomatous Polyposis Coli Protein; Animals; Blotting, Western; Cells, Cultured; Colon; Diet; Enterocytes; Epithelial Cells; Female; Folic Acid; Gene Expression Profiling; Glycine Hydroxymethyltransferase; Heterozygote; Immunohistochemistry; Intestinal Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Oligonucleotide Array Sequence Analysis; Purines; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; Thymine Nucleotides

2011
Melanoma coordinates general and cell-specific mechanisms to promote methotrexate resistance.
    Experimental cell research, 2012, Jun-10, Volume: 318, Issue:10

    Topics: Amino Acid Sequence; Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Checkpoint Kinase 1; Drug Resistance, Neoplasm; E2F1 Transcription Factor; Enzyme Activation; Folic Acid; Humans; Melanoma; Methotrexate; Mice; Molecular Sequence Data; Protein Kinases; Protein Processing, Post-Translational; S Phase Cell Cycle Checkpoints; Skin Neoplasms; Tetrahydrofolate Dehydrogenase; Thymidylate Synthase; Thymine Nucleotides; Transcription, Genetic

2012
Mitochondrial translation requires folate-dependent tRNA methylation.
    Nature, 2018, 02-01, Volume: 554, Issue:7690

    Topics: Aminohydrolases; Biocatalysis; Carrier Proteins; Codon; Electron Transport; Folic Acid; Folic Acid Antagonists; Glycine Hydroxymethyltransferase; GTP-Binding Proteins; Guanosine; HCT116 Cells; HEK293 Cells; Humans; Leucine; Lysine; Methylation; Methylenetetrahydrofolate Dehydrogenase (NADP); Mitochondria; Multifunctional Enzymes; Oxidative Phosphorylation; Protein Biosynthesis; Ribosomes; RNA-Binding Proteins; RNA, Transfer; Sarcosine; Tetrahydrofolates; Thymine Nucleotides

2018
Inactivation of folylpolyglutamate synthetase Met7 results in genome instability driven by an increased dUTP/dTTP ratio.
    Nucleic acids research, 2020, 01-10, Volume: 48, Issue:1

    Topics: Cell Nucleus; Deoxyguanine Nucleotides; Deoxyuracil Nucleotides; DNA Damage; DNA, Fungal; Folic Acid; Gene Deletion; Gene Expression Regulation, Fungal; Genome, Fungal; Genomic Instability; Mitochondria; Mutation; Peptide Synthases; Saccharomyces cerevisiae; Thymine Nucleotides; Uracil

2020
Folic acid alleviates age-related cognitive decline and inhibits apoptosis of neurocytes in senescence-accelerated mouse prone 8: deoxythymidine triphosphate biosynthesis as a potential mechanism.
    The Journal of nutritional biochemistry, 2021, Volume: 97

    Topics: Aging; Animals; Apoptosis; Brain; Cognitive Dysfunction; Dietary Supplements; Folic Acid; Male; Memory; Mice; Morris Water Maze Test; Neurons; Quinazolines; Telomere Shortening; Thiophenes; Thymidylate Synthase; Thymine Nucleotides; Uracil

2021