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thymidine 5'-triphosphate and floxuridine

thymidine 5'-triphosphate has been researched along with floxuridine in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19907 (46.67)18.7374
1990's6 (40.00)18.2507
2000's1 (6.67)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Daikoku, T; Maeno, K; Nishiyama, Y; Yamamoto, N1
Davis, MA; Ensminger, WD; Lawrence, TS; Maybaum, J; McKeever, PE; Normolle, DP; Stetson, PL1
Fischer, PH; Risueno, C; Vazquez-Padua, MA1
Cranford, SK; Fernandes, DJ1
Danenberg, PV; Ibric, LL; Peterson, AR; Peterson, H1
Bestwick, RK; Mathews, CK; Moffett, GL1
Tyrsted, G1
Cohen, A; Ullman, B1
Feller, W; Follmann, H; Schimpff-Weiland, G1
Cloos, L; Hofbauer, R; Mortensen, BT; Munch-Petersen, B; Tyrsted, G; Völker, C1
Collins, MK; López-Rivas, A; Marvel, J; Oliver, FJ1
Ahluwalia, GS; Gao, WY; Johns, DG; Mitsuya, H1
Gao, WY; Johns, DG; Mitsuya, H; Tanaka, M1
Eklund, H; Mikkelsen, NE; Munch-Petersen, B1
Chen, CM; Dornfeld, K; Johnson, M; Smith, BJ1

Reviews

1 review(s) available for thymidine 5'-triphosphate and floxuridine

ArticleYear
Deoxyribonucleoside-induced selective modulation of cytotoxicity and mutagenesis.
    Basic life sciences, 1985, Volume: 31

    Topics: Alkylating Agents; Animals; Azaguanine; Cell Line; Cell Survival; Cricetinae; Deoxyadenosines; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanosine; Deoxyribonucleosides; DNA; Drug Resistance; Drug Synergism; Floxuridine; Leukemia L1210; Lung; Methylation; Methylnitronitrosoguanidine; Mice; Mutagens; Mutation; Thymidine; Thymidylate Synthase; Thymine Nucleotides

1985

Other Studies

14 other study(ies) available for thymidine 5'-triphosphate and floxuridine

ArticleYear
Role of viral ribonucleotide reductase in the increase of dTTP pool size in herpes simplex virus-infected Vero cells.
    The Journal of general virology, 1991, Volume: 72 ( Pt 6)

    Topics: Animals; Chromosome Deletion; Floxuridine; Hydroxyurea; Kinetics; Phosphorylation; Ribonucleotide Reductases; Simplexvirus; Thymidine; Thymine Nucleotides; Vero Cells; Virus Replication

1991
Fluorodeoxyuridine-mediated modulation of iododeoxyuridine incorporation and radiosensitization in human colon cancer cells in vitro and in vivo.
    Cancer research, 1991, Aug-01, Volume: 51, Issue:15

    Topics: Animals; Cell Cycle; Colonic Neoplasms; DNA Damage; DNA Repair; DNA, Neoplasm; Dose-Response Relationship, Drug; Floxuridine; Humans; Idoxuridine; Kinetics; Mice; Mice, Nude; Neoplasm Transplantation; Radiation Tolerance; Thymine Nucleotides; Tumor Cells, Cultured

1991
Regulation of the activation of fluorodeoxyuridine by substrate competition and feedback inhibition in 647V cells.
    Cancer research, 1989, Feb-01, Volume: 49, Issue:3

    Topics: Cell Line; Floxuridine; Humans; Models, Biological; Phosphorylation; Thymidine Kinase; Thymine Nucleotides; Urinary Bladder Neoplasms

1989
Dissociation of thymidylate biosynthesis from DNA biosynthesis by 5-fluoro-2'-deoxyuridine and 5,8-dideazaisofolic acid.
    Cancer research, 1986, Volume: 46, Issue:4 Pt 1

    Topics: Deoxyguanine Nucleotides; DNA; DNA Polymerase II; Dose-Response Relationship, Drug; Floxuridine; Folic Acid Antagonists; Humans; Leukemia; Pyrimethamine; Quinazolines; Thymidine Monophosphate; Thymidylate Synthase; Thymine Nucleotides

1986
Selective expansion of mitochondrial nucleoside triphosphate pools in antimetabolite-treated HeLa cells.
    The Journal of biological chemistry, 1982, Aug-25, Volume: 257, Issue:16

    Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA; Floxuridine; HeLa Cells; Humans; Methotrexate; Mitochondria; Ribonucleotides; Thymine Nucleotides

1982
Effect of hydroxyurea and 5-fluorodeoxyuridine on deoxyribonucleoside triphosphate pools early in phytohemagglutinin-stimulated human lymphocytes.
    Biochemical pharmacology, 1982, Oct-01, Volume: 31, Issue:19

    Topics: Deoxyribonucleotides; DNA; Floxuridine; Humans; Hydroxyurea; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Thymine Nucleotides

1982
Role of intracellular dTTP levels in fluorodeoxyuridine toxicity.
    Biochemical pharmacology, 1984, Oct-15, Volume: 33, Issue:20

    Topics: Animals; Cell Line; Floxuridine; Lymphoma; Mice; Mutation; Nucleosides; Thymidylate Synthase; Thymine Nucleotides

1984
Deoxyribonucleotide biosynthesis in synchronous algae cells.
    European journal of biochemistry, 1980, Volume: 110, Issue:1

    Topics: Cell Cycle; Chlorophyta; Deoxyribonucleotides; DNA; Floxuridine; Light; Periodicity; Ribonucleoside Diphosphate Reductase; Thymine Nucleotides

1980
Altered substrate and inhibitor specificity of purified human adult thymidine kinases (TK2) from leukemic cells.
    Advances in experimental medicine and biology, 1994, Volume: 370

    Topics: Adult; Cell Line; Floxuridine; Humans; Isoenzymes; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Reference Values; Substrate Specificity; Thymidine Kinase; Thymine Nucleotides; Tumor Cells, Cultured; Zidovudine

1994
Bcl-2 oncogene protects a bone marrow-derived pre-B-cell line from 5'-fluor,2'-deoxyuridine-induced apoptosis.
    Biochemical and biophysical research communications, 1993, Jul-15, Volume: 194, Issue:1

    Topics: Animals; Apoptosis; B-Lymphocytes; Cell Line; Cell Survival; Deoxyadenine Nucleotides; Dose-Response Relationship, Drug; Floxuridine; Hematopoietic Stem Cells; Humans; Kinetics; Mice; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogenes; Thymine Nucleotides; Transfection

1993
2',3'-Didehydro-3'-deoxythymidine: regulation of its metabolic activation by modulators of thymidine-5'-triphosphate biosynthesis.
    Molecular pharmacology, 1996, Volume: 50, Issue:1

    Topics: Amides; Biotransformation; Biphenyl Compounds; Cell Line; Deoxyguanosine; Floxuridine; HIV; HIV Reverse Transcriptase; HIV-1; Humans; Hydroxyurea; Kinetics; Methotrexate; Models, Biological; Phosphorylation; Pyrazoles; Reverse Transcriptase Inhibitors; Ribonucleosides; Ribose; RNA-Directed DNA Polymerase; Stavudine; Thymidine Kinase; Thymine Nucleotides; Tumor Cells, Cultured

1996
Suppression of replication of multidrug-resistant HIV type 1 variants by combinations of thymidylate synthase inhibitors with zidovudine or stavudine.
    Molecular pharmacology, 1999, Volume: 55, Issue:3

    Topics: Anti-HIV Agents; Antimetabolites; Drug Interactions; Drug Resistance, Microbial; Drug Resistance, Multiple; Floxuridine; Fluorouracil; HIV-1; Humans; Mutation; Reverse Transcriptase Inhibitors; Stavudine; Thymidylate Synthase; Thymine Nucleotides; Virus Replication; Zidovudine

1999
Structural studies of nucleoside analog and feedback inhibitor binding to Drosophila melanogaster multisubstrate deoxyribonucleoside kinase.
    The FEBS journal, 2008, Volume: 275, Issue:9

    Topics: Adenosine Diphosphate; Animals; Antimetabolites; Bromodeoxyuridine; Cytarabine; Cytidine Triphosphate; Drosophila melanogaster; Drosophila Proteins; Feedback; Floxuridine; Guanosine Triphosphate; Hydrogen Bonding; Inhibitory Concentration 50; Kinetics; Models, Chemical; Models, Molecular; Phosphotransferases (Alcohol Group Acceptor); Protein Binding; Protein Structure, Secondary; Structure-Activity Relationship; Thymine Nucleotides; X-Ray Diffraction; Zalcitabine; Zidovudine

2008
Azidothymidine enhances fluorodeoxyuridine-mediated radiosensitization.
    International journal of radiation oncology, biology, physics, 2010, Mar-01, Volume: 76, Issue:3

    Topics: Antimetabolites; Cell Cycle; Cell Line, Tumor; Cell Survival; Colony-Forming Units Assay; Deoxyuracil Nucleotides; DNA Breaks, Single-Stranded; DNA Damage; DNA Mismatch Repair; Drug Synergism; Flow Cytometry; Floxuridine; Humans; MutS Homolog 2 Protein; Poisson Distribution; Radiation Tolerance; Thymidine; Thymine Nucleotides; Zidovudine

2010