Page last updated: 2024-08-24

thymidine 5'-triphosphate and deoxyuridine triphosphate

thymidine 5'-triphosphate has been researched along with deoxyuridine triphosphate in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19906 (21.43)18.7374
1990's15 (53.57)18.2507
2000's4 (14.29)29.6817
2010's1 (3.57)24.3611
2020's2 (7.14)2.80

Authors

AuthorsStudies
Focher, F; Mazzarello, P; Spadari, S; Verri, A; Verzeletti, S1
Chu, CK; Hirota, K; Hosono, H; Kitade, Y; Maki, Y; Nakane, H; Ono, K; Schinazi, RF1
Bevan, IS; Day, PJ; Gurney, SJ; Walker, MR; Young, LS1
Aherne, GW; Aitkenhead, S; Curtin, N; Piall, E1
Adolph, S1
Mosbaugh, DW1
Boose, B; Spector, R1
Gauri, KK; Koch, G; Kowalzick, L; Kühne, J; Pedrali-Noy, G; Spadari, S1
Abbott, LG; Fraenkel-Conrat, H; Singer, B; Spengler, SJ1
Craddock, BP; Kano, T; Steigbigel, RT; Suzuki, K1
Alseth, I; Eftedal, I; Krokan, HE; Slupphaug, G; Volden, G1
Olson, JC; Pu, R; Vyas, GN; Yang, G1
Allen, RH; Chandler, CJ; Halsted, CH; James, SJ; Muskhelishvili, L; Poirier, L; Stabler, SP; Villanueva, J1
Song, S1
Horowitz, RW; Ladner, RD; Schwartz, EL; Wadler, S; Zhang, H1
Connor, JD; Poddar, SK; Sawyer, MH1
Gretz, DM; Henning, SM; Jacob, RA; James, SJ; Miller, BJ; Pogribny, IP; Swendseid, ME; Taylor, PC1
Fujikawa, K; Kamiya, H; Kasai, H1
Erlichman, C; Kaufmann, SH; Mullany, S; Svingen, PA1
Degtiarev, SKh; Dezhurov, SV; Khodyreva, SN; Kolpashchikov, DM; Lavrik, OI; Litvak, VV; Rechkunova, NI; Zakharenko, AL1
Berkenblit, R; Damle, S; Haynes, H; Kaleya, R; Ladner, RD; Murgo, A; Schechner, R; Wadler, S1
Ebara, Y; Kaihatsu, K; Sugiyama, T; Ueji, S1
Dionne, I; Toussaint, M; Wellinger, RJ1
Arndt, KM; Bernauer, HS; Knall, S; Müller, KM; Stebel, SC; Zipf, G1
Bernardi, P; Bianchi, V; Ferraro, P; Nicolosi, L; Reichard, P1
Chen, CM; Dornfeld, K; Johnson, M; Smith, BJ1
González-Pacanowska, D; Martínez-Arribas, B; Pérez-Moreno, G; Requena, CE; Ruíz-Pérez, LM; Vidal, AE1
Chabes, A; Hofer, A; Hombauer, H; Kolodziejczak, A; Luke, B; Reyes, GX; Schmidt, TT; Sharma, S; Wagner, T1

Trials

1 trial(s) available for thymidine 5'-triphosphate and deoxyuridine triphosphate

ArticleYear
Phase II/pharmacodynamic trial of dose-intensive, weekly parenteral hydroxyurea and fluorouracil administered with interferon alfa-2a in patients with refractory malignancies of the gastrointestinal tract.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Deoxyuracil Nucleotides; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fluorouracil; Humans; Hydroxyurea; Interferon alpha-2; Interferon-alpha; Leukocytes, Mononuclear; Male; Middle Aged; Pancreatic Neoplasms; Prospective Studies; Recombinant Proteins; Stomach Neoplasms; Thymine Nucleotides; Treatment Outcome

1999

Other Studies

27 other study(ies) available for thymidine 5'-triphosphate and deoxyuridine triphosphate

ArticleYear
Uracil in OriS of herpes simplex 1 alters its specific recognition by origin binding protein (OBP): does virus induced uracil-DNA glycosylase play a key role in viral reactivation and replication?
    Chromosoma, 1992, Volume: 102, Issue:1 Suppl

    Topics: Base Sequence; Cytosine; Deamination; Deoxyuracil Nucleotides; DNA Glycosylases; DNA Replication; DNA-Binding Proteins; Molecular Sequence Data; N-Glycosyl Hydrolases; Replicon; Simplexvirus; Thymine Nucleotides; Uracil; Uracil-DNA Glycosidase; Viral Proteins; Virus Activation; Virus Replication

1992
Synthesis and anti-human immunodeficiency virus (HIV-1) activity of 3'-deoxy-3'-(triazol-1-yl)thymidines and 2',3'-dideoxy-3'-(triazol-1-yl)uridines and inhibition of reverse transcriptase by their 5'-triphosphates.
    Chemical & pharmaceutical bulletin, 1990, Volume: 38, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Deoxyuracil Nucleotides; HIV-1; Humans; Reverse Transcriptase Inhibitors; Thymine Nucleotides

1990
Synthesis in vitro and application of biotinylated DNA probes for human papilloma virus type 16 by utilizing the polymerase chain reaction.
    The Biochemical journal, 1990, Apr-01, Volume: 267, Issue:1

    Topics: Base Sequence; Biotin; Deoxyadenine Nucleotides; Deoxyuracil Nucleotides; DNA Probes; DNA, Viral; Gene Amplification; Molecular Sequence Data; Nucleic Acid Hybridization; Papillomaviridae; Polymerase Chain Reaction; Thymine Nucleotides

1990
A radioimmunoassay for deoxythymidine triphosphate.
    Biochemical Society transactions, 1989, Volume: 17, Issue:6

    Topics: Antimetabolites; Deoxyuracil Nucleotides; Humans; Radioimmunoassay; Thymine Nucleotides; Tumor Cells, Cultured

1989
In situ nick translation distinguishes between C-band positive regions on mouse chromosomes.
    Chromosoma, 1988, Volume: 96, Issue:2

    Topics: Animals; Biotin; Centromere; Chromosome Banding; Deoxyribonuclease I; Deoxyuracil Nucleotides; DNA Replication; DNA Restriction Enzymes; Heterochromatin; Metaphase; Mice; Thymine Nucleotides; Translocation, Genetic; Tritium

1988
Purification and characterization of porcine liver DNA polymerase gamma: utilization of dUTP and dTTP during in vitro DNA synthesis.
    Nucleic acids research, 1988, Jun-24, Volume: 16, Issue:12

    Topics: Animals; Chromatography, Affinity; Chromatography, Ion Exchange; Deoxyuracil Nucleotides; DNA Polymerase III; DNA Replication; DNA-Directed DNA Polymerase; Kinetics; Mitochondria, Liver; Substrate Specificity; Swine; Thymine Nucleotides

1988
Identification and partial characterization of rabbit brain deoxyuridine 5'-triphosphatase.
    Neurochemical research, 1983, Volume: 8, Issue:8

    Topics: Animals; Brain; Deoxyuracil Nucleotides; Deoxyuridine; DNA; Drug Stability; Hot Temperature; Kinetics; Nucleoside-Triphosphatase; Phosphoric Monoester Hydrolases; Pyrophosphatases; Rabbits; Thymine Nucleotides

1983
Differential incorporation of thymidylate analogues into DNA by DNA polymerase alpha and by DNA polymerases specified by two herpes simplex viruses.
    The Journal of general virology, 1982, Volume: 62 (Pt 1)

    Topics: Deoxyuracil Nucleotides; DNA; DNA Polymerase II; DNA-Directed DNA Polymerase; HeLa Cells; Humans; Kinetics; Simplexvirus; Substrate Specificity; Thymine Nucleotides; Trifluridine

1982
N4-Methoxydeoxycytidine triphosphate is in the imino tautomeric form and substitutes for deoxythymidine triphosphate in primed poly d[A-T] synthesis with E. coli DNA polymerase I.
    Nucleic acids research, 1984, Jun-11, Volume: 12, Issue:11

    Topics: Base Sequence; Carbon Radioisotopes; Deoxycytosine Nucleotides; DNA Polymerase I; DNA Replication; Escherichia coli; Nucleic Acid Denaturation; Poly dA-dT; Polydeoxyribonucleotides; Structure-Activity Relationship; Templates, Genetic; Thymine Nucleotides; Transcription, Genetic; Tritium

1984
Colorimetric reverse transcriptase assay for HIV-1.
    Journal of virological methods, 1993, Volume: 41, Issue:1

    Topics: Biotin; Cell Line; Colorimetry; Deoxyuracil Nucleotides; Digoxigenin; Evaluation Studies as Topic; HIV Reverse Transcriptase; HIV-1; Humans; Reference Standards; RNA-Directed DNA Polymerase; Thymine Nucleotides; Tritium; Virology

1993
Low incorporation of dUMP by some thermostable DNA polymerases may limit their use in PCR amplifications.
    Analytical biochemistry, 1993, May-15, Volume: 211, Issue:1

    Topics: Bacteria; Base Sequence; Deoxyuracil Nucleotides; DNA-Directed DNA Polymerase; Enzyme Stability; Hot Temperature; Molecular Sequence Data; Polymerase Chain Reaction; Substrate Specificity; Thymine Nucleotides

1993
Flow cytometric detection of human immunodeficiency virus type 1 proviral DNA by the polymerase chain reaction incorporating digoxigenin- or fluorescein-labeled dUTP.
    Cytometry, 1995, Oct-01, Volume: 21, Issue:2

    Topics: Base Sequence; Deoxyuracil Nucleotides; Digoxigenin; DNA, Viral; Flow Cytometry; Fluoresceins; Fluorescent Dyes; HIV Infections; HIV-1; Humans; Molecular Sequence Data; Oligonucleotide Probes; Oligonucleotides, Antisense; Polymerase Chain Reaction; Proviruses; Thymine Nucleotides

1995
Ethanol feeding of micropigs alters methionine metabolism and increases hepatocellular apoptosis and proliferation.
    Hepatology (Baltimore, Md.), 1996, Volume: 23, Issue:3

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Administration, Oral; Analysis of Variance; Animal Feed; Animals; Apoptosis; Cell Division; Deoxyuracil Nucleotides; Ethanol; Folic Acid; Homocysteine; Liver; Male; Methionine; Proliferating Cell Nuclear Antigen; S-Adenosylhomocysteine; S-Adenosylmethionine; Swine; Swine, Miniature; Thymine Nucleotides

1996
Application of fluorescent dUTP on PCR and automated PCR product detection by using internal lane size standard.
    Nucleic acids symposium series, 1995, Issue:34

    Topics: Color; Deoxyuracil Nucleotides; Electrophoresis, Polyacrylamide Gel; Evaluation Studies as Topic; Fluorescent Dyes; Indicators and Reagents; Polymerase Chain Reaction; Reference Standards; Thymine Nucleotides

1995
Measurement of deoxyuridine triphosphate and thymidine triphosphate in the extracts of thymidylate synthase-inhibited cells using a modified DNA polymerase assay.
    Biochemical pharmacology, 1997, Sep-01, Volume: 54, Issue:5

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Colonic Neoplasms; Deoxyuracil Nucleotides; DNA-Directed DNA Polymerase; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Kinetics; Pyrophosphatases; Quinazolines; Templates, Genetic; Thiophenes; Thymidylate Synthase; Thymine Nucleotides; Tumor Cells, Cultured

1997
Optimized PCR amplification of influenza A virus RNA using Tth DNA polymerase, incorporating uracil N glycosylase (UNG) in a single tube reaction.
    Journal of clinical laboratory analysis, 1997, Volume: 11, Issue:6

    Topics: Deoxyuracil Nucleotides; DNA Glycosylases; DNA-Directed DNA Polymerase; Humans; Influenza A virus; N-Glycosyl Hydrolases; Nasopharynx; Polymerase Chain Reaction; RNA, Viral; Thermus thermophilus; Thymine Nucleotides; Uracil-DNA Glycosidase

1997
Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women.
    The Journal of nutrition, 1998, Volume: 128, Issue:7

    Topics: Creatinine; Deoxyuracil Nucleotides; Diet; DNA Methylation; Female; Folic Acid; Homocysteine; Humans; Lymphocytes; Malondialdehyde; Middle Aged; Mitogens; Nutritional Requirements; Postmenopause; Thymine Nucleotides; Vitamin B 12

1998
The mutations induced by oxidatively damaged nucleotides, 5-formyl-dUTP and 5-hydroxy-dCTP,in Escherichia coli.
    Nucleic acids research, 1998, Oct-15, Volume: 26, Issue:20

    Topics: Bacterial Proteins; Deoxyadenine Nucleotides; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyuracil Nucleotides; Deoxyuridine; DNA Mutational Analysis; DNA Repair; Escherichia coli; Escherichia coli Proteins; Genome, Bacterial; Lac Repressors; Models, Genetic; Mutagenesis; Nucleic Acid Hybridization; Oxidants; Point Mutation; Repressor Proteins; Sequence Analysis, DNA; Thymine Nucleotides

1998
Effect of adding the topoisomerase I poison 7-ethyl-10-hydroxycamptothecin (SN-38) to 5-fluorouracil and folinic acid in HCT-8 cells: elevated dTTP pools and enhanced cytotoxicity.
    Cancer chemotherapy and pharmacology, 1998, Volume: 42, Issue:5

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Cycle; Cell Survival; Deoxyuracil Nucleotides; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Fluorouracil; Humans; Intestinal Neoplasms; Irinotecan; Leucovorin; Thymidylate Synthase; Thymine Nucleotides; Topoisomerase I Inhibitors; Tumor Cells, Cultured

1998
[New reagents for affinity modification of biopolymers. Photoaffinity modification of Tte-DNA polymerase].
    Bioorganicheskaia khimiia, 1999, Volume: 25, Issue:2

    Topics: Azides; Base Sequence; beta-Alanine; Biopolymers; Deoxyuracil Nucleotides; DNA Primers; DNA-Directed DNA Polymerase; Glycine; Photoaffinity Labels; Spectrophotometry, Ultraviolet; Thermus thermophilus; Thymine Nucleotides

1999
Synthesis of non-natural DNA using DNA polymerase.
    Nucleic acids symposium series, 2000, Issue:44

    Topics: Base Sequence; Deoxyuracil Nucleotides; DNA; DNA Polymerase I; Drug Design; Galactose; Glucose; Models, Molecular; Molecular Structure; Nucleic Acid Conformation; Substrate Specificity; Thymine Nucleotides

2000
Limited TTP supply affects telomere length regulation in a telomerase-independent fashion.
    Nucleic acids research, 2005, Volume: 33, Issue:2

    Topics: Cell Growth Processes; Deoxyuracil Nucleotides; Mutation; Nucleoside-Phosphate Kinase; Nucleotides; Saccharomyces cerevisiae; Telomerase; Telomere; Thymidylate Synthase; Thymine Nucleotides

2005
Nucleotide exchange and excision technology (NExT) DNA shuffling: a robust method for DNA fragmentation and directed evolution.
    Nucleic acids research, 2005, Aug-01, Volume: 33, Issue:13

    Topics: Chloramphenicol O-Acetyltransferase; Deoxyribonuclease (Pyrimidine Dimer); Deoxyuracil Nucleotides; Directed Molecular Evolution; DNA Fragmentation; DNA Shuffling; DNA-Directed DNA Polymerase; Electrophoresis, Polyacrylamide Gel; Gene Library; Nucleotides; Piperidines; Polymerase Chain Reaction; Software; Taq Polymerase; Thymine Nucleotides

2005
Mitochondrial deoxynucleotide pool sizes in mouse liver and evidence for a transport mechanism for thymidine monophosphate.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Dec-05, Volume: 103, Issue:49

    Topics: Animals; Biological Transport, Active; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyuracil Nucleotides; Male; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Thymidine Monophosphate; Thymine Nucleotides

2006
Azidothymidine enhances fluorodeoxyuridine-mediated radiosensitization.
    International journal of radiation oncology, biology, physics, 2010, Mar-01, Volume: 76, Issue:3

    Topics: Antimetabolites; Cell Cycle; Cell Line, Tumor; Cell Survival; Colony-Forming Units Assay; Deoxyuracil Nucleotides; DNA Breaks, Single-Stranded; DNA Damage; DNA Mismatch Repair; Drug Synergism; Flow Cytometry; Floxuridine; Humans; MutS Homolog 2 Protein; Poisson Distribution; Radiation Tolerance; Thymidine; Thymine Nucleotides; Zidovudine

2010
DCTPP1 prevents a mutator phenotype through the modulation of dCTP, dTTP and dUTP pools.
    Cellular and molecular life sciences : CMLS, 2020, Volume: 77, Issue:8

    Topics: Cell Line; Cell Proliferation; Deoxycytosine Nucleotides; Deoxyuracil Nucleotides; DNA Damage; Gene Knockout Techniques; Genomic Instability; Humans; MCF-7 Cells; Mutation; Pyrophosphatases; Thymine Nucleotides

2020
Inactivation of folylpolyglutamate synthetase Met7 results in genome instability driven by an increased dUTP/dTTP ratio.
    Nucleic acids research, 2020, 01-10, Volume: 48, Issue:1

    Topics: Cell Nucleus; Deoxyguanine Nucleotides; Deoxyuracil Nucleotides; DNA Damage; DNA, Fungal; Folic Acid; Gene Deletion; Gene Expression Regulation, Fungal; Genome, Fungal; Genomic Instability; Mitochondria; Mutation; Peptide Synthases; Saccharomyces cerevisiae; Thymine Nucleotides; Uracil

2020