Compounds > thymidine 5'-triphosphate
Page last updated: 2024-08-24

thymidine 5'-triphosphate and deoxyguanosine triphosphate

thymidine 5'-triphosphate has been researched along with deoxyguanosine triphosphate in 92 studies

Research

Studies (92)

TimeframeStudies, this research(%)All Research%
pre-199031 (33.70)18.7374
1990's20 (21.74)18.2507
2000's26 (28.26)29.6817
2010's11 (11.96)24.3611
2020's4 (4.35)2.80

Authors

AuthorsStudies
Hanes, JW; Johnson, KA; Parris, DS; Zhu, Y1
Amblard, F; Bassit, L; Bondada, L; Coats, SJ; Detorio, M; Grier, J; Hernandez-Santiago, BI; Koontz, D; Mellors, JW; Rapp, KL; Schinazi, RF; Sluis-Cremer, N1
Meanwell, NA1
Fuchs, JA; Manwaring, JD1
Buckheit, RW; Germany, JM; Parker, WB; Ross, LJ; Secrist, JA; Shaddix, SC; Shannon, WM; Vince, R; White, EL1
Brumley, J; Hayman, RJ; Rose, IS; van der Weyden, MB1
Höglund, L; Pontis, E; Reichard, P1
Bastow, KF; Cheng, YC; Dutschman, GE; Sarngadharan, MG; Ting, RY1
Bakker, MA; Bökkerink, JP; De Abreu, RA; De Bruijn, CH; Hulscher, TW; Schretlen, ED; van Baal, JM1
Schroeder, AL; Srivastava, VK1
Fyfe, JA; Sherman, PA1
Frick, LW; Nelson, DJ1
Cranford, SK; Fernandes, DJ1
Cheng, YC; Grill, SP; Nutter, LM1
Razzaki, T; Sinha, NK1
Eriksson, S; Skog, S; Tribukait, B; Wallström, B1
Dresler, SL; Frattini, MG; Robinson-Hill, RM1
Lagergren, J; Reichard, P1
Carlquist, M; Eriksson, S; Jörnvall, H; Sjöberg, BM1
Bianchi, V; Pontis, E; Reichard, P1
Lecomte, P; Ninio, J; Papanicolaou, C1
Fox, RM1
Bestwick, RK; Mathews, CK; Moffett, GL1
Furman, PA; Lambe, CU; Nelson, DJ1
Goto, H; Ogasawara, N; Yamada, Y1
Tanaka, K; Tanaka, S; Wataya, Y; Yoshioka, A1
Appel, H; Leyva, A; Pinedo, HM1
Eriksson, S1
Jackson, RC1
Ikegami, S; Nagano, H; Okano, K1
Snyder, RD1
Cory, JG; Sato, A1
Ganeshaguru, K; Hoffbrand, AV; Lee, N; Piga, A; Prentice, HG; Russell, NH; Smyth, JF1
Caras, IW; Martin, DW1
Bestwick, RK; Mathews, CK1
Bianchi, V; Darè, E; Jenssen, D; Zhang, LH1
Desai, SD; Modak, MJ; Pandey, VN1
Eliasson, R; Pontis, E; Reichard, P; Sun, X1
Eriksson, S; Hultgren, C; Karlsson, A; Meyerhans, A; Plikat, U; Vartanian, JP; Wain-Hobson, S; Wang, L1
Rappaport, HP1
Ingemarson, R; Thelander, L1
Avidan, O; Bakhanashvili, M; Hizi, A1
Aulabaugh, AE; Boone, LR; Boyd, FL; Daluge, SM; Davis, MG; Freeman, GA; Miller, WH; Painter, GR; VanDraanen, NA; Wilson, JE1
Xing, W1
Alur, P; Dornadula, G; Laughlin, MA; Pomerantz, RJ; Zhang, H1
Hizi, A; Hughes, SH; Perach, M; Rubinek, T1
Arion, D; Borkow, G; Fletcher, RS; Gu, Z; Holleschak, G; Nagy, E; Parniak, MA; Wainberg, MA1
Meuth, M1
Elstein, KH; Kavlock, RJ; Lau, C; Mole, ML; Rogers, JM; Setzer, RW; Zucker, RM1
Anderson, KS; Kerr, SG1
Fujikawa, K; Kamiya, H; Kasai, H1
Bogue, M; Meek, K; Mickelsen, S; Roth, DB; Snyder, C; Trujillo, K1
Kuchta, RD; Mazurkiewicz, A; Richardson, FC; Richardson, KA1
Ishikawa, F; Saito, M; Saneyoshi, M; Shudo, K; Yamada, R; Yamaguchi, T1
Enger, MD; Gurley, LR; Ratliff, RL; Tobey, RA; Walters, RA1
Heeger, P; Mynatt, RL; Truett, AA; Truett, GE; Walker, JA; Warman, ML1
da Silva, EF; Reha-Krantz, LJ1
Chimploy, K; Mathews, CK; Tassotto, ML1
Ishikawa, F; Saito, M; Saneyoshi, M; Shudo, K; Tomikawa, A; Yamada, R; Yamaguchi, T1
Hardin, SH; Kraltcheva, AI1
Amin, S; Geacintov, NE; Kolbanovskiy, A; Zhuang, P1
Cech, TR; Sperger, JM1
Fagny, C; Robberecht, P; Svoboda, M; Vandevelde, M1
Collins, S; Gerard, GF; Smith, MD1
Bassett, E; Chaney, SG; Gauger, M; Havener, JM; Nick McElhinny, SA; Ramsden, DA1
Mathews, CK; Song, S; Wheeler, LJ1
Bertram, JG; Bloom, LB; Goodman, MF; O'Donnell, M1
Dong, Y; Fiala, KA; Roettger, MP; Sompalli, S; Suo, Z1
Konigsberg, W; Wang, J; Yang, G1
Hayakawa, H; Ishibashi, T; Ito, R; Sekiguchi, M1
Hamby, K; Persson, K; Ugozzoli, LA1
Cramer, J; Restle, T1
Broyde, S; Patel, DJ; Rechkoblit, O; Shapiro, R; Wang, L; Zhang, L1
Bernardi, P; Bianchi, V; Ferraro, P; Nicolosi, L; Reichard, P1
Chilkoti, A; Chow, DC1
Arakawa, H; Kamahori, M; Kambara, H; Karasawa, K; Maeda, M; Munakata, E; Obinata, R; Suzuki, S1
Broyde, S; Donny-Clark, K1
Radivoyevitch, T1
Abdulovic, AL; Chabes, A; Kumar, D; Kunkel, TA; Nilsson, AK; Viberg, J1
Christodoulou, E; Crow, YJ; de Carvalho, LP; Ennis-Adeniran, V; Goldstone, DC; Groom, HC; Haire, LF; Hedden, JJ; Kelly, G; Rice, GI; Stoye, JP; Taylor, IA; Walker, PA; Webb, M; Yap, MW1
Cho, BP; Vaidyanathan, VG; Xu, L1
Cafarelli, TM; Godoy, VG; Rands, TJ1
Fijalkowska, IJ; Gawel, D; Jonczyk, P; Schaaper, RM1
Buckland, RJ; Chabes, A; Chittoor, B; Kunkel, TA; Nilsson, AK; Watt, DL1
Akman, G; Cámara, Y; Dalla Rosa, I; Durigon, R; Elgar, G; Grocott, S; Hirano, M; Holt, IJ; Hunt, L; Johnson, MA; Martí, R; Moss, CF; Poulton, J; Spinazzola, A; Taylor, RW; Thorburn, DR; Vidoni, S; Voshol, P; Wang, L1
Anderson, PL; Bushman, LR; Castillo-Mancilla, JR; Chen, X; MaWhinney, S; McAllister, KB; Seifert, SM; Zheng, JH1
Wetmore, SD; Wilson, KA1
Hassan, C; Herdewijn, P; Louis, D; Marlière, P; Pezo, V; Sargueil, B1
Chabes, A; Hofer, A; Hombauer, H; Kolodziejczak, A; Luke, B; Reyes, GX; Schmidt, TT; Sharma, S; Wagner, T1
Chang, ZF; González-Pacanowska, D; Huang, CY; Yagüe-Capilla, M1
Jung, H; Koag, MC; Lee, S1
Dubovskaja, V; Jasponė, A; Kapustina, Ž; Lubys, A; Mackevičius, G1

Reviews

2 review(s) available for thymidine 5'-triphosphate and deoxyguanosine triphosphate

ArticleYear
Changes in deoxynucleoside triphosphate pools induced by inhibitors and modulators of ribonucleotide reductase.
    Pharmacology & therapeutics, 1985, Volume: 30, Issue:1

    Topics: Animals; Aziridines; Cells, Cultured; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; Humans; Hydroxyurea; Ribonucleotide Reductases; Substrate Specificity; T-Lymphocytes; Thiosemicarbazones; Thymine Nucleotides

1985
A kinetic model of regulation of the deoxyribonucleoside triphosphate pool composition.
    Pharmacology & therapeutics, 1984, Volume: 24, Issue:2

    Topics: Animals; Antimetabolites; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleosides; Deoxyribonucleotides; DNA; Humans; Kinetics; Liver Neoplasms, Experimental; Models, Biological; Nucleic Acid Synthesis Inhibitors; Ribonucleoside Diphosphate Reductase; Thermodynamics; Thymidylate Synthase; Thymine Nucleotides

1984

Trials

1 trial(s) available for thymidine 5'-triphosphate and deoxyguanosine triphosphate

ArticleYear
Analysis of the Endogenous Deoxynucleoside Triphosphate Pool in HIV-Positive and -Negative Individuals Receiving Tenofovir-Emtricitabine.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:9

    Topics: Adult; Anti-HIV Agents; Case-Control Studies; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Emtricitabine; Female; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Linear Models; Male; Tenofovir; Thymine Nucleotides

2016

Other Studies

89 other study(ies) available for thymidine 5'-triphosphate and deoxyguanosine triphosphate

ArticleYear
Enzymatic therapeutic index of acyclovir. Viral versus human polymerase gamma specificity.
    The Journal of biological chemistry, 2007, Aug-24, Volume: 282, Issue:34

    Topics: Acyclovir; Animals; Antiviral Agents; DNA Polymerase gamma; DNA-Directed DNA Polymerase; DNA, Mitochondrial; Dose-Response Relationship, Drug; Exonucleases; Herpesvirus 1, Human; Humans; Insecta; Kinetics; Models, Biological; Substrate Specificity; Time Factors; Virus Replication

2007
Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:9

    Topics: Anti-HIV Agents; Cell Line, Tumor; Cell Survival; Cells, Cultured; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Molecular Structure; Reverse Transcriptase Inhibitors

2009
Synopsis of some recent tactical application of bioisosteres in drug design.
    Journal of medicinal chemistry, 2011, Apr-28, Volume: 54, Issue:8

    Topics: Cytochrome P-450 Enzyme System; Drug Design

2011
Nucleoside triphosphate pools in minicells of Escherichia coli.
    Journal of bacteriology, 1977, Volume: 130, Issue:2

    Topics: Adenosine Triphosphate; Cytidine Triphosphate; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Escherichia coli; Guanosine Triphosphate; Nucleotides; Thymine Nucleotides; Uridine Triphosphate

1977
Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase and human DNA polymerases alpha, beta, and gamma by the 5'-triphosphates of carbovir, 3'-azido-3'-deoxythymidine, 2',3'-dideoxyguanosine and 3'-deoxythymidine. A novel RN
    The Journal of biological chemistry, 1991, Jan-25, Volume: 266, Issue:3

    Topics: Antiviral Agents; Base Sequence; Deoxyguanine Nucleotides; Dideoxynucleotides; DNA; DNA Polymerase I; DNA Polymerase II; DNA Polymerase III; HIV-1; Humans; In Vitro Techniques; Kinetics; Molecular Sequence Data; Reverse Transcriptase Inhibitors; RNA; Templates, Genetic; Thymine Nucleotides; Zidovudine

1991
Folate-deficient human lymphoblasts: changes in deoxynucleotide metabolism and thymidylate cycle activities.
    European journal of haematology, 1991, Volume: 47, Issue:2

    Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyuridine; Dose-Response Relationship, Drug; Folic Acid; Folic Acid Deficiency; Humans; Lymphocyte Activation; Lymphocytes; Nucleotides; Thymidine; Thymidylate Synthase; Thymine Nucleotides

1991
Deoxyribonucleotide metabolism in hydroxyurea-resistant V79 hamster cells.
    European journal of biochemistry, 1991, Feb-26, Volume: 196, Issue:1

    Topics: Animals; Cell Line; Cricetinae; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA; Drug Resistance; Hydroxyurea; Thymine Nucleotides

1991
Human immunodeficiency virus reverse transcriptase. General properties and its interactions with nucleoside triphosphate analogs.
    The Journal of biological chemistry, 1987, Feb-15, Volume: 262, Issue:5

    Topics: Deoxyguanine Nucleotides; HIV; Humans; Kinetics; Molecular Weight; Nucleotides; RNA-Directed DNA Polymerase; Structure-Activity Relationship; Substrate Specificity; Thymine Nucleotides

1987
Effects of methotrexate on purine and pyrimidine metabolism and cell-kinetic parameters in human malignant lymphoblasts of different lineages.
    Biochemical pharmacology, 1988, Jun-15, Volume: 37, Issue:12

    Topics: Cell Cycle; Cell Survival; Deoxyguanine Nucleotides; Humans; Leukemia; Lymphocytes; Methotrexate; Polyglutamic Acid; Purines; Pyrimidines; RNA; Thymine Nucleotides; Tumor Cells, Cultured

1988
Deoxyribonucleoside triphosphate pools in mutagen sensitive mutants of Neurospora crassa.
    Biochemical and biophysical research communications, 1989, Jul-31, Volume: 162, Issue:2

    Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA, Fungal; Genes, Fungal; Histidine; Hydroxyurea; Mutation; Neurospora; Neurospora crassa; Thymine Nucleotides

1989
Enzymatic assay for deoxyribonucleoside triphosphates using synthetic oligonucleotides as template primers.
    Analytical biochemistry, 1989, Aug-01, Volume: 180, Issue:2

    Topics: Base Sequence; Cells, Cultured; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA-Directed DNA Polymerase; Humans; Micrococcus; Oligonucleotides; Perchlorates; Poly dA-dT; Reference Standards; Templates, Genetic; Thymine Nucleotides; Tritium

1989
Effects of 3'-azido-3'-deoxythymidine on the deoxynucleoside triphosphate pools of cultured human cells.
    Advances in experimental medicine and biology, 1989, Volume: 253B

    Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Dose-Response Relationship, Drug; Humans; Nucleoside-Phosphate Kinase; Thymine Nucleotides; Tumor Cells, Cultured; Zidovudine

1989
Dissociation of thymidylate biosynthesis from DNA biosynthesis by 5-fluoro-2'-deoxyuridine and 5,8-dideazaisofolic acid.
    Cancer research, 1986, Volume: 46, Issue:4 Pt 1

    Topics: Deoxyguanine Nucleotides; DNA; DNA Polymerase II; Dose-Response Relationship, Drug; Floxuridine; Folic Acid Antagonists; Humans; Leukemia; Pyrimethamine; Quinazolines; Thymidine Monophosphate; Thymidylate Synthase; Thymine Nucleotides

1986
Can ribonucleotide reductase be considered as an effective target for developing antiherpes simplex virus type II (HSV-2) compounds?
    Biochemical pharmacology, 1985, Mar-15, Volume: 34, Issue:6

    Topics: Antiviral Agents; Cytidine; Deoxyguanine Nucleotides; DNA, Viral; HeLa Cells; Humans; Hydroxyurea; Phosphates; Ribonucleotide Reductases; Simplexvirus; Thymine Nucleotides

1985
Effect of variations in the conditions of DNA synthesis upon the accuracy of DNA replication.
    Basic life sciences, 1985, Volume: 31

    Topics: Bacteriophage phi X 174; Base Sequence; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; Deoxyuracil Nucleotides; Diphosphates; DNA Replication; DNA-Directed DNA Polymerase; DNA, Viral; Intercalating Agents; Manganese; Mutation; Thymine Nucleotides

1985
Deoxyribonucleoside triphosphate metabolism and the mammalian cell cycle. Effects of hydroxyurea on mutant and wild-type mouse S49 T-lymphoma cells.
    Experimental cell research, 1987, Volume: 168, Issue:1

    Topics: Animals; Cell Cycle; Cell Line; Deoxyadenine Nucleotides; Deoxycytidine Kinase; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; Hydroxyurea; Lymphoma; Mice; Mutation; Purine-Nucleoside Phosphorylase; Ribonucleotide Reductases; T-Lymphocytes; Thymidine Kinase; Thymine Nucleotides

1987
In situ enzymology of DNA replication and ultraviolet-induced DNA repair synthesis in permeable human cells.
    Biochemistry, 1988, Sep-20, Volume: 27, Issue:19

    Topics: Cell Line; Cell Membrane Permeability; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA; DNA Polymerase II; DNA Polymerase III; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; Fibroblasts; Humans; Potassium Chloride; Thymine Nucleotides; Ultraviolet Rays

1988
Purine deoxyribonucleosides counteract effects of hydroxyurea on deoxyribonucleoside triphosphate pools and DNA synthesis.
    Biochemical pharmacology, 1987, Sep-15, Volume: 36, Issue:18

    Topics: Animals; Cell Line; Cricetinae; Deoxyadenine Nucleotides; Deoxyadenosines; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyguanosine; DNA; Hydroxyurea; Nucleotides; Purine Nucleosides; Thymine Nucleotides

1987
A photoaffinity-labeled allosteric site in Escherichia coli ribonucleotide reductase.
    The Journal of biological chemistry, 1986, Feb-05, Volume: 261, Issue:4

    Topics: Adenosine Triphosphate; Affinity Labels; Allosteric Regulation; Allosteric Site; Amino Acid Sequence; Bacterial Proteins; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Chromatography, Thin Layer; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; Escherichia coli; Peptides; Ribonucleotide Reductases; Thymine Nucleotides

1986
Changes of deoxyribonucleoside triphosphate pools induced by hydroxyurea and their relation to DNA synthesis.
    The Journal of biological chemistry, 1986, Dec-05, Volume: 261, Issue:34

    Topics: Cells, Cultured; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA; Hydroxyurea; Ribonucleotide Reductases; Thymine Nucleotides

1986
Mnemonic aspects of Escherichia coli DNA polymerase I. Interaction with one template influences the next interaction with another template.
    Journal of molecular biology, 1986, Jun-05, Volume: 189, Issue:3

    Topics: Base Composition; Deoxyadenine Nucleotides; Deoxycytidine Monophosphate; Deoxyguanine Nucleotides; DNA Polymerase I; DNA Replication; Escherichia coli; Kinetics; Models, Biological; Poly dA-dT; Templates, Genetic; Thymine Nucleotides

1986
Selective expansion of mitochondrial nucleoside triphosphate pools in antimetabolite-treated HeLa cells.
    The Journal of biological chemistry, 1982, Aug-25, Volume: 257, Issue:16

    Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA; Floxuridine; HeLa Cells; Humans; Methotrexate; Mitochondria; Ribonucleotides; Thymine Nucleotides

1982
Effect of acyclovir on the deoxyribonucleoside triphosphate pool levels in Vero cells infected with herpes simplex virus type 1.
    The American journal of medicine, 1982, Jul-20, Volume: 73, Issue:1A

    Topics: Acyclovir; Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; Guanine; Phosphonoacetic Acid; Simplexvirus; Thymine Nucleotides

1982
Regulation of human placental deoxyguanosine kinase by nucleotides.
    FEBS letters, 1983, Jun-27, Volume: 157, Issue:1

    Topics: Deoxyguanine Nucleotides; Enzyme Activation; Female; Humans; Nucleotides; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Placenta; Thymine Nucleotides

1983
An improved method for the quantitative determination of deoxyribonucleoside triphosphates in cell extracts.
    Analytical biochemistry, 1984, May-15, Volume: 139, Issue:1

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Extracts; Chromatography, High Pressure Liquid; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; Male; Methylamines; Mice; Oxidation-Reduction; Periodic Acid; Ribonucleotides; Thymine Nucleotides; Tissue Extracts

1984
Diverse deoxyribonucleotide profiles in cultured human cells with differential sensitivity to thymidine.
    Cancer biochemistry biophysics, 1984, Volume: 7, Issue:3

    Topics: B-Lymphocytes; Cell Line; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; Humans; Melanoma; T-Lymphocytes; Thymidine; Thymine Nucleotides

1984
Direct photoaffinity labeling of ribonucleotide reductase from Escherichia coli. Evidence for enhanced binding of the allosteric effector dTTP by the presence of substrates.
    The Journal of biological chemistry, 1983, May-10, Volume: 258, Issue:9

    Topics: Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; Escherichia coli; Guanosine Diphosphate; Macromolecular Substances; Photochemistry; Ribonucleotide Reductases; Thymine Nucleotides

1983
Changes in deoxyribonucleoside triphosphate pools in the starfish oocyte during maturation and early embryogenesis.
    Experimental cell research, 1983, Apr-15, Volume: 145, Issue:1

    Topics: Animals; Aphidicolin; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; Diterpenes; Female; Oocytes; Oogenesis; Ovum; Starfish; Thymine Nucleotides; Zygote

1983
Deoxyribonucleoside triphosphate pools in human diploid fibroblasts and their modulation by hydroxyurea and deoxynucleosides.
    Biochemical pharmacology, 1984, May-01, Volume: 33, Issue:9

    Topics: Cells, Cultured; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleosides; Deoxyribonucleotides; Diploidy; Fibroblasts; Humans; Hydroxyurea; Thymine Nucleotides

1984
Evaluation of combinations of drugs that inhibit Ehrlich tumor cell ribonucleotide reductase.
    Cancer research, 1981, Volume: 41, Issue:5

    Topics: Aldehydes; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; Drug Interactions; Drug Synergism; Edetic Acid; Hydroxyurea; Imidazoles; Inosine; Isoquinolines; Mice; Pyrazoles; Ribonucleotide Reductases; Thiosemicarbazones; Thymine Nucleotides

1981
Studies on the biochemical sequelae of therapy in Thy-acute lymphoblastic leukaemia with the adenosine deaminase inhibitor 2' deoxycoformycin.
    British journal of haematology, 1981, Volume: 49, Issue:1

    Topics: Adenosine Deaminase; Adenosylhomocysteinase; Adolescent; Adult; Bone Marrow; Coformycin; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Humans; Hydrolases; Leukemia, Lymphoid; Leukocyte Count; Male; Pentostatin; Ribonucleosides; Thymine Nucleotides

1981
Direct photoaffinity labeling of an allosteric site of subunit protein M1 of mouse ribonucleotide reductase by dATP. Evidence for two independent binding interactions within the allosteric specificity site.
    The Journal of biological chemistry, 1982, Aug-25, Volume: 257, Issue:16

    Topics: Affinity Labels; Allosteric Site; Animals; Binding Sites; Binding, Competitive; Cell Line; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; Lymphoma, Non-Hodgkin; Mice; Mutation; Neoplasms, Experimental; Ribonucleotide Reductases; Thymine Nucleotides; Ultraviolet Rays

1982
Unusual compartmentation of precursors for nuclear and mitochondrial DNA in mouse L cells.
    The Journal of biological chemistry, 1982, Aug-25, Volume: 257, Issue:16

    Topics: Animals; Cell Compartmentation; Cell Nucleus; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA; L Cells; Mice; Mitochondria; Phosphorus Radioisotopes; Thymine Nucleotides; Tritium; Uridine

1982
Molecular analysis of mutations in the hprt gene of V79 hamster fibroblasts: effects of imbalances in the dCTP, dGTP and dTTP pools.
    Journal of molecular biology, 1995, Oct-06, Volume: 252, Issue:5

    Topics: Animals; Cell Line; Cricetinae; Cytidine; DCMP Deaminase; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA Replication; Fibroblasts; Hypoxanthine Phosphoribosyltransferase; Mutation; Thymidine; Thymine Nucleotides

1995
Properties of tyrosine 766-->serine mutant of Escherichia coli DNA polymerase I: template-specific effects.
    Biochemistry, 1994, Oct-04, Volume: 33, Issue:39

    Topics: Base Sequence; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA; DNA Adducts; DNA Polymerase I; DNA Primers; Escherichia coli; Molecular Sequence Data; Mutation; Serine; Substrate Specificity; Thymine Nucleotides; Tyrosine; Ultraviolet Rays

1994
Allosteric control of the substrate specificity of the anaerobic ribonucleotide reductase from Escherichia coli.
    The Journal of biological chemistry, 1994, Oct-21, Volume: 269, Issue:42

    Topics: Adenosine Triphosphate; Allosteric Regulation; Anaerobiosis; Binding, Competitive; Deoxyguanine Nucleotides; Escherichia coli; Kinetics; Ribonucleotide Reductases; Substrate Specificity; Thymine Nucleotides

1994
Restriction and enhancement of human immunodeficiency virus type 1 replication by modulation of intracellular deoxynucleoside triphosphate pools.
    Journal of virology, 1994, Volume: 68, Issue:1

    Topics: CD4 Antigens; Cells, Cultured; Deoxyadenine Nucleotides; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; HIV-1; Humans; Proviruses; Thymidine; Thymine Nucleotides; Transcription, Genetic; Virus Replication

1994
Replication of the base pair 6-thioguanine/5-methyl-2-pyrimidine with the large Klenow fragment of Escherichia coli DNA polymerase I.
    Biochemistry, 1993, Mar-30, Volume: 32, Issue:12

    Topics: Base Composition; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; DNA Polymerase I; DNA Replication; Escherichia coli; Exodeoxyribonuclease V; Exodeoxyribonucleases; Kinetics; Mathematics; Models, Biological; Pyrimidinones; Templates, Genetic; Thioguanine; Thymine Nucleotides

1993
A kinetic study on the influence of nucleoside triphosphate effectors on subunit interaction in mouse ribonucleotide reductase.
    Biochemistry, 1996, Jul-02, Volume: 35, Issue:26

    Topics: Adenosine Triphosphate; Allosteric Regulation; Animals; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; Kinetics; Mice; Protein Binding; Ribonucleotide Reductases; Thymine Nucleotides

1996
Mutational studies of human immunodeficiency virus type 1 reverse transcriptase: the involvement of residues 183 and 184 in the fidelity of DNA synthesis.
    FEBS letters, 1996, Aug-12, Volume: 391, Issue:3

    Topics: Base Sequence; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA Replication; DNA, Viral; Electrophoresis, Polyacrylamide Gel; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Molecular Sequence Data; Mutation; RNA-Directed DNA Polymerase; Thymine Nucleotides

1996
DNA polymerase activity of hepatitis B virus particles: differential inhibition by L-enantiomers of nucleotide analogs.
    Antiviral research, 1996, Volume: 30, Issue:2-3

    Topics: Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA-Directed DNA Polymerase; DNA, Viral; Emtricitabine; Hepatitis B virus; Humans; Isotope Labeling; Nucleic Acid Synthesis Inhibitors; Nucleotides; Templates, Genetic; Thymine Nucleotides; Zalcitabine

1996
Effects of dNTPs on the sister-chromatid exchange (SCE) frequency in human lymphocytes.
    Mutation research, 1996, Sep-23, Volume: 356, Issue:2

    Topics: Bromodeoxyuridine; Cells, Cultured; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Dose-Response Relationship, Drug; Humans; Sister Chromatid Exchange; T-Lymphocytes; Thymine Nucleotides

1996
Amphipathic domains in the C terminus of the transmembrane protein (gp41) permeabilize HIV-1 virions: a molecular mechanism underlying natural endogenous reverse transcription.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Oct-29, Volume: 93, Issue:22

    Topics: Animals; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; HIV Envelope Protein gp41; HIV Reverse Transcriptase; HIV-1; Humans; Mice; Permeability; Rats; Thymine Nucleotides; Transcription, Genetic; Virion

1996
Analysis of HIV-2 RT mutants provides evidence that resistance of HIV-1 RT and HIV-2 RT to nucleoside analogs involves a repositioning of the template-primer.
    Journal of molecular biology, 1997, May-09, Volume: 268, Issue:3

    Topics: Deoxyguanine Nucleotides; Deoxyribonucleotides; Dideoxynucleotides; DNA Primers; DNA, Viral; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Models, Molecular; Mutation; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Templates, Genetic; Thymine Nucleotides

1997
Single-step purification of recombinant wild-type and mutant HIV-1 reverse transcriptase.
    Protein expression and purification, 1996, Volume: 7, Issue:1

    Topics: Blotting, Western; Chromatography, High Pressure Liquid; Deoxyguanine Nucleotides; Dimerization; DNA-Directed DNA Polymerase; Electrophoresis, Polyacrylamide Gel; Escherichia coli; HIV Reverse Transcriptase; Isoenzymes; Kinetics; Molecular Weight; Mutation; Oligodeoxyribonucleotides; Poly A; Polymerase Chain Reaction; Protein Conformation; Recombinant Proteins; Thymine Nucleotides

1996
Sensitivity of a mutator gene in Chinese hamster ovary cell to deoxynucleoside triphosphate pool alterations.
    Molecular and cellular biology, 1981, Volume: 1, Issue:7

    Topics: Animals; CHO Cells; Cricetinae; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Emetine; Female; Mutation; Ovary; Protein Synthesis Inhibitors; Thymidine; Thymine Nucleotides

1981
Nucleoside-mediated mitigation of 5-fluorouracil-induced toxicity in synchronized murine erythroleukemic cells.
    Toxicology and applied pharmacology, 1997, Volume: 146, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Cell Cycle; Deoxycytidine; Deoxyguanine Nucleotides; Embryo, Mammalian; Female; Flow Cytometry; Fluorouracil; Leukemia, Erythroblastic, Acute; Mice; Pregnancy; Rats; Rats, Sprague-Dawley; Thymidine; Thymine Nucleotides

1997
RNA dependent DNA replication fidelity of HIV-1 reverse transcriptase: evidence of discrimination between DNA and RNA substrates.
    Biochemistry, 1997, Nov-18, Volume: 36, Issue:46

    Topics: Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA Primers; DNA Replication; DNA, Viral; Escherichia coli; HIV Reverse Transcriptase; HIV-1; Kinetics; Recombinant Proteins; Substrate Specificity; Thymine Nucleotides

1997
The mutations induced by oxidatively damaged nucleotides, 5-formyl-dUTP and 5-hydroxy-dCTP,in Escherichia coli.
    Nucleic acids research, 1998, Oct-15, Volume: 26, Issue:20

    Topics: Bacterial Proteins; Deoxyadenine Nucleotides; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyuracil Nucleotides; Deoxyuridine; DNA Mutational Analysis; DNA Repair; Escherichia coli; Escherichia coli Proteins; Genome, Bacterial; Lac Repressors; Models, Genetic; Mutagenesis; Nucleic Acid Hybridization; Oxidants; Point Mutation; Repressor Proteins; Sequence Analysis, DNA; Thymine Nucleotides

1998
Modulation of terminal deoxynucleotidyltransferase activity by the DNA-dependent protein kinase.
    Journal of immunology (Baltimore, Md. : 1950), 1999, Jul-15, Volume: 163, Issue:2

    Topics: Animals; Catalysis; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA Nucleotidylexotransferase; DNA-Activated Protein Kinase; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Humans; Mice; Mice, SCID; Nuclear Proteins; Oligonucleotides; Protein Serine-Threonine Kinases; Substrate Specificity; Thymine Nucleotides; Tumor Cells, Cultured

1999
Polymerization of 2'-fluoro- and 2'-O-methyl-dNTPs by human DNA polymerase alpha, polymerase gamma, and primase.
    Biochemical pharmacology, 2000, May-01, Volume: 59, Issue:9

    Topics: Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA Polymerase gamma; DNA Polymerase I; DNA Primase; DNA-Directed DNA Polymerase; Humans; Thymine Nucleotides; Uridine Triphosphate

2000
Inhibitory effects of of L-2'-deoxyguanosine 5'-triphosphate (L-dGTP) and L-2'-deoxythymidine 5'-triphosphate (L-dTTP) on human telomerase.
    Nucleic acids symposium series, 1999, Issue:42

    Topics: Base Sequence; Deoxyguanine Nucleotides; DNA Primers; HeLa Cells; Humans; Kinetics; Polymerase Chain Reaction; Stereoisomerism; Telomerase; Thymine Nucleotides

1999
Effects of X-irradiation on DNA precursor metabolism and deoxyribonucleoside triphosphate pools in Chinese hamster cells.
    Radiation research, 1974, Volume: 60, Issue:1

    Topics: Animals; CHO Cells; Cricetinae; Cytidine; Deoxyadenine Nucleotides; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA Damage; DNA Repair; DNA Replication; Dose-Response Relationship, Radiation; Intracellular Fluid; RNA; S Phase; Thymidine; Thymine Nucleotides

1974
Preparation of PCR-quality mouse genomic DNA with hot sodium hydroxide and tris (HotSHOT).
    BioTechniques, 2000, Volume: 29, Issue:1

    Topics: Aging; Animals; Buffers; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA; Hot Temperature; Hydrogen-Ion Concentration; Indicators and Reagents; Magnesium Chloride; Mice; Polymerase Chain Reaction; Sodium Hydroxide; Solubility; Taq Polymerase; Thymine Nucleotides

2000
Dinucleotide repeat expansion catalyzed by bacteriophage T4 DNA polymerase in vitro.
    The Journal of biological chemistry, 2000, Oct-06, Volume: 275, Issue:40

    Topics: Deoxyguanine Nucleotides; DNA Polymerase I; DNA Primers; DNA-Directed DNA Polymerase; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Models, Genetic; Repetitive Sequences, Nucleic Acid; Thymine Nucleotides; Time Factors; Viral Proteins

2000
Ribonucleotide reductase, a possible agent in deoxyribonucleotide pool asymmetries induced by hypoxia.
    The Journal of biological chemistry, 2000, Dec-15, Volume: 275, Issue:50

    Topics: Animals; Cells, Cultured; Cricetinae; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; Hydrogen-Ion Concentration; Hydroxyurea; Hypoxia; Mice; Models, Chemical; Nucleic Acid Synthesis Inhibitors; Oxygen; Recombinant Proteins; Ribonucleotide Reductases; Thymine Nucleotides; Time Factors

2000
Recognition of 2'-deoxy-l-ribonucleoside 5'-triphosphates by human telomerase.
    Biochemical and biophysical research communications, 2000, Dec-20, Volume: 279, Issue:2

    Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; Humans; Kinetics; Stereoisomerism; Substrate Specificity; Telomerase; Thymine Nucleotides

2000
Octamer-primed sequencing technology: effects of dNTP supplementation.
    Nucleic acids research, 2001, May-15, Volume: 29, Issue:10

    Topics: Base Composition; Base Sequence; Deoxyguanine Nucleotides; DNA; DNA Primers; Gene Library; Molecular Sequence Data; Molecular Weight; Nucleotides; Oligodeoxyribonucleotides; Sensitivity and Specificity; Sequence Analysis, DNA; Taq Polymerase; Templates, Genetic; Thymine Nucleotides; Time Factors

2001
Base sequence dependence of in vitro translesional DNA replication past a bulky lesion catalyzed by the exo- Klenow fragment of Pol I.
    Biochemistry, 2001, Jun-05, Volume: 40, Issue:22

    Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Base Sequence; Carcinogens, Environmental; Catalysis; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyguanosine; DNA Damage; DNA Polymerase I; DNA Primers; DNA Replication; Guanine; Kinetics; Mutagenesis; Mutagens; Polydeoxyribonucleotides; Pyrimidine Nucleotides; Sequence Analysis, DNA; Templates, Genetic; Thymine Nucleotides

2001
A stem-loop of Tetrahymena telomerase RNA distant from the template potentiates RNA folding and telomerase activity.
    Biochemistry, 2001, Jun-19, Volume: 40, Issue:24

    Topics: Animals; Base Sequence; Binding Sites; Deoxyguanine Nucleotides; DNA-Binding Proteins; Endoribonucleases; Enzyme Activation; Molecular Sequence Data; Nucleic Acid Conformation; Rabbits; RNA; RNA, Protozoan; Sequence Deletion; Telomerase; Templates, Genetic; Tetrahymena thermophila; Thymine Nucleotides

2001
Ribonucleotide reductase and thymidine phosphorylation: two potential targets of azodicarbonamide.
    Biochemical pharmacology, 2002, Aug-01, Volume: 64, Issue:3

    Topics: Animals; Antineoplastic Agents; Azo Compounds; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Drug Interactions; Hydroxyurea; Immunosuppressive Agents; Methotrexate; Phosphorylation; Ribonucleotide Reductases; Thymidine; Thymine Nucleotides; Tumor Cells, Cultured

2002
Excess dNTPs minimize RNA hydrolysis during reverse transcription.
    BioTechniques, 2002, Volume: 33, Issue:5

    Topics: Avian Sarcoma Viruses; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA, Complementary; Drug Stability; Electrophoresis, Agar Gel; Half-Life; Hot Temperature; Hydrolysis; Magnesium; Moloney murine leukemia virus; Nucleic Acid Denaturation; RNA; RNA-Directed DNA Polymerase; Thymine Nucleotides; Transcription, Genetic; Viral Proteins

2002
Translesion synthesis past platinum DNA adducts by human DNA polymerase mu.
    Biochemistry, 2003, Feb-18, Volume: 42, Issue:6

    Topics: Catalysis; Cisplatin; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; DNA Adducts; DNA Damage; DNA Primers; DNA-Directed DNA Polymerase; DNA, Single-Stranded; Guanine Nucleotides; Humans; Oligonucleotides; Organoplatinum Compounds; Oxaliplatin; Templates, Genetic; Thymine Nucleotides

2003
Deoxyribonucleotide pool imbalance stimulates deletions in HeLa cell mitochondrial DNA.
    The Journal of biological chemistry, 2003, Nov-07, Volume: 278, Issue:45

    Topics: Base Pairing; Blotting, Southern; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA, Mitochondrial; Gastrointestinal Diseases; Gene Deletion; HeLa Cells; Humans; Mitochondria; Mitochondrial Encephalomyopathies; Point Mutation; Polymerase Chain Reaction; Thymidine; Thymine Nucleotides

2003
Increased dNTP binding affinity reveals a nonprocessive role for Escherichia coli beta clamp with DNA polymerase IV.
    The Journal of biological chemistry, 2004, Aug-06, Volume: 279, Issue:32

    Topics: Base Pair Mismatch; Binding Sites; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA; DNA Polymerase beta; DNA Polymerase III; DNA Primers; Escherichia coli; Fluorescence Polarization; Frameshift Mutation; Kinetics; Oligodeoxyribonucleotides; Templates, Genetic; Thymine Nucleotides

2004
Pre-steady-state kinetic studies of the fidelity of human DNA polymerase mu.
    Biochemistry, 2004, Nov-02, Volume: 43, Issue:43

    Topics: Binding Sites; Buffers; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA; DNA Nucleotidylexotransferase; DNA Primers; DNA-Directed DNA Polymerase; Enzyme Activation; Enzyme Stability; Humans; Kinetics; Peptide Chain Elongation, Translational; Ribonucleotides; Substrate Specificity; Templates, Genetic; Thymine Nucleotides; Uridine Triphosphate

2004
Base selectivity is impaired by mutants that perturb hydrogen bonding networks in the RB69 DNA polymerase active site.
    Biochemistry, 2005, Mar-08, Volume: 44, Issue:9

    Topics: Alanine; Amino Acid Substitution; Base Pair Mismatch; Binding Sites; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA-Directed DNA Polymerase; Enterobacter; Hydrogen Bonding; Kinetics; Nucleotides; Phenylalanine; Substrate Specificity; Thymine Nucleotides; Toluene; Tyrosine; Viral Proteins

2005
Multiple enzyme activities of Escherichia coli MutT protein for sanitization of DNA and RNA precursor pools.
    Biochemistry, 2005, May-03, Volume: 44, Issue:17

    Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA Replication; DNA, Bacterial; Escherichia coli Proteins; Guanine; Guanosine Triphosphate; Hydrolysis; Kinetics; Multienzyme Complexes; Phosphoric Monoester Hydrolases; Pyrophosphatases; RNA, Bacterial; Thymine Nucleotides; Transcription, Genetic

2005
Four-color multiplex reverse transcription polymerase chain reaction--overcoming its limitations.
    Analytical biochemistry, 2005, Sep-01, Volume: 344, Issue:1

    Topics: Color; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA Primers; DNA Probes; DNA, Complementary; Gene Expression; Reverse Transcriptase Polymerase Chain Reaction; Taq Polymerase; Thymine Nucleotides

2005
Pre-steady-state kinetic characterization of the DinB homologue DNA polymerase of Sulfolobus solfataricus.
    The Journal of biological chemistry, 2005, Dec-09, Volume: 280, Issue:49

    Topics: Archaeal Proteins; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA; DNA-Directed DNA Polymerase; Kinetics; Thymine Nucleotides

2005
Mutagenic nucleotide incorporation and hindered translocation by a food carcinogen C8-dG adduct in Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): modeling and dynamics studies.
    Nucleic acids research, 2006, Volume: 34, Issue:11

    Topics: Binding Sites; Carcinogens; Computational Biology; Computer Simulation; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyguanosine; Deoxyribonucleotides; DNA; DNA Adducts; DNA Polymerase beta; Imidazoles; Models, Molecular; Motion; Mutagenesis; Nucleic Acid Conformation; Sulfolobus solfataricus; Thymine Nucleotides

2006
Mitochondrial deoxynucleotide pool sizes in mouse liver and evidence for a transport mechanism for thymidine monophosphate.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Dec-05, Volume: 103, Issue:49

    Topics: Animals; Biological Transport, Active; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyuracil Nucleotides; Male; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Thymidine Monophosphate; Thymine Nucleotides

2006
Surface-initiated enzymatic polymerization of DNA.
    Langmuir : the ACS journal of surfaces and colloids, 2007, Nov-06, Volume: 23, Issue:23

    Topics: Antibodies; Antibody Specificity; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; DNA Nucleotidylexotransferase; DNA, Single-Stranded; Microscopy, Atomic Force; Nanotechnology; Oligonucleotides; Polydeoxyribonucleotides; Spectrometry, X-Ray Emission; Surface Plasmon Resonance; Surface Properties; Thymine Nucleotides; Time Factors

2007
Development of bioluminescent pyrophosphate assay using pyruvate phosphate dikinase and its application to single-nucleotide polymorphism analysis.
    Analytical biochemistry, 2008, Aug-01, Volume: 379, Issue:1

    Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Diphosphates; DNA; Luciferases; Luminescent Measurements; Models, Biological; Polymorphism, Single Nucleotide; Pyruvate, Orthophosphate Dikinase; ras Proteins; Reproducibility of Results; Thionucleotides; Thymine Nucleotides; Tumor Suppressor Protein p53

2008
Influence of local sequence context on damaged base conformation in human DNA polymerase iota: molecular dynamics studies of nucleotide incorporation opposite a benzo[a]pyrene-derived adenine lesion.
    Nucleic acids research, 2009, Volume: 37, Issue:21

    Topics: Base Pair Mismatch; Base Pairing; Base Sequence; Benzopyrenes; Carcinogens, Environmental; Computer Simulation; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA Adducts; DNA Damage; DNA Polymerase iota; DNA-Directed DNA Polymerase; Humans; Hydrogen Bonding; Magnesium; Models, Molecular; Nucleic Acid Conformation; Thymine Nucleotides

2009
Automated mass action model space generation and analysis methods for two-reactant combinatorially complex equilibriums: an analysis of ATP-induced ribonucleotide reductase R1 hexamerization data.
    Biology direct, 2009, Dec-09, Volume: 4

    Topics: Adenosine Triphosphate; Catalytic Domain; Computer Simulation; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; Humans; Least-Squares Analysis; Models, Biological; Nonlinear Dynamics; Protein Multimerization; Protein Subunits; Ribonucleotide Reductases; Substrate Specificity; Thymine Nucleotides

2009
Mechanisms of mutagenesis in vivo due to imbalanced dNTP pools.
    Nucleic acids research, 2011, Volume: 39, Issue:4

    Topics: Amino Acid Substitution; Amino Acid Transport Systems, Basic; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; INDEL Mutation; Mutagenesis; Mutation; Ribonucleotide Reductases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thymine Nucleotides

2011
HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase.
    Nature, 2011, Nov-06, Volume: 480, Issue:7377

    Topics: Allosteric Regulation; Biocatalysis; Catalytic Domain; Crystallography, X-Ray; Dendritic Cells; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; HIV-1; Humans; Hydrolysis; Models, Biological; Models, Molecular; Monomeric GTP-Binding Proteins; Myeloid Cells; Nucleoside-Triphosphatase; Protein Structure, Tertiary; Reverse Transcription; SAM Domain and HD Domain-Containing Protein 1; Thymine Nucleotides; Viral Regulatory and Accessory Proteins; Virus Replication

2011
Binary and ternary binding affinities between exonuclease-deficient Klenow fragment (Kf-exo(-)) and various arylamine DNA lesions characterized by surface plasmon resonance.
    Chemical research in toxicology, 2012, Aug-20, Volume: 25, Issue:8

    Topics: 2-Acetylaminofluorene; Aminobiphenyl Compounds; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA; DNA Adducts; DNA Polymerase I; Fluorenes; Kinetics; Surface Plasmon Resonance; Thymine Nucleotides

2012
The DinB•RecA complex of Escherichia coli mediates an efficient and high-fidelity response to ubiquitous alkylation lesions.
    Environmental and molecular mutagenesis, 2014, Volume: 55, Issue:2

    Topics: Adenine; Alkylation; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA Adducts; DNA Replication; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Kinetics; Mutagenesis; Rec A Recombinases; Thymine Nucleotides

2014
Effect of dNTP pool alterations on fidelity of leading and lagging strand DNA replication in E. coli.
    Mutation research, 2014, Volume: 759

    Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA Replication; Escherichia coli; Lac Operon; Thymine Nucleotides

2014
Increased and imbalanced dNTP pools symmetrically promote both leading and lagging strand replication infidelity.
    PLoS genetics, 2014, Volume: 10, Issue:12

    Topics: Base Pair Mismatch; Base Sequence; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA Mismatch Repair; DNA Replication; Genomic Instability; Molecular Sequence Data; Mutagenesis; Mutation Rate; Organisms, Genetically Modified; Saccharomyces cerevisiae; Thymine Nucleotides

2014
MPV17 Loss Causes Deoxynucleotide Insufficiency and Slow DNA Replication in Mitochondria.
    PLoS genetics, 2016, Volume: 12, Issue:1

    Topics: Animals; Deoxyguanine Nucleotides; DNA Replication; DNA, Mitochondrial; Female; Fibroblasts; Gene Expression Regulation; Humans; Membrane Proteins; Mice; Mitochondria, Liver; Signal Transduction; Thymine Nucleotides

2016
Molecular Insights into the Translesion Synthesis of Benzyl-Guanine from Molecular Dynamics Simulations: Structural Evidence of Mutagenic and Nonmutagenic Replication.
    Biochemistry, 2017, 04-04, Volume: 56, Issue:13

    Topics: Benzyl Compounds; Catalytic Domain; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA Adducts; DNA Damage; DNA Polymerase beta; DNA Repair; DNA Replication; Escherichia coli; Escherichia coli Proteins; Guanine; Hydrogen Bonding; Molecular Dynamics Simulation; Mutagenesis; Protein Structure, Secondary; Protein Structure, Tertiary; Thymine Nucleotides

2017
Metabolic Recruitment and Directed Evolution of Nucleoside Triphosphate Uptake in Escherichia coli.
    ACS synthetic biology, 2018, 06-15, Volume: 7, Issue:6

    Topics: Bacterial Outer Membrane Proteins; Decitabine; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; Directed Molecular Evolution; Escherichia coli; Escherichia coli Proteins; Microalgae; Microorganisms, Genetically-Modified; Mutation Rate; Peptide Hydrolases; Thymidine Kinase; Thymidylate Synthase; Thymine Nucleotides

2018
Inactivation of folylpolyglutamate synthetase Met7 results in genome instability driven by an increased dUTP/dTTP ratio.
    Nucleic acids research, 2020, 01-10, Volume: 48, Issue:1

    Topics: Cell Nucleus; Deoxyguanine Nucleotides; Deoxyuracil Nucleotides; DNA Damage; DNA, Fungal; Folic Acid; Gene Deletion; Gene Expression Regulation, Fungal; Genome, Fungal; Genomic Instability; Mitochondria; Mutation; Peptide Synthases; Saccharomyces cerevisiae; Thymine Nucleotides; Uracil

2020
Quantitation of deoxynucleoside triphosphates by click reactions.
    Scientific reports, 2020, 01-17, Volume: 10, Issue:1

    Topics: Click Chemistry; Copper; Cycloaddition Reaction; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; Deoxyuracil Nucleotides; HCT116 Cells; HEK293 Cells; Humans; K562 Cells; Rhodamines; Staining and Labeling; Thymine Nucleotides

2020
Mutagenesis mechanism of the major oxidative adenine lesion 7,8-dihydro-8-oxoadenine.
    Nucleic acids research, 2020, 05-21, Volume: 48, Issue:9

    Topics: Adenine; Base Pairing; Deoxyguanine Nucleotides; DNA Polymerase beta; DNA-Directed DNA Polymerase; Humans; Kinetics; Mutagenesis; Mutation; Thymine Nucleotides

2020
Enzymatic Synthesis of Chimeric DNA Oligonucleotides by
    ACS synthetic biology, 2021, 07-16, Volume: 10, Issue:7

    Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA-Directed RNA Polymerases; Fluorine; Substrate Specificity; Synthetic Biology; Thymine Nucleotides; Transcription, Genetic; Viral Proteins

2021