thymidine 5'-triphosphate has been researched along with 2'-deoxyadenosine triphosphate in 89 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (32.58) | 18.7374 |
| 1990's | 17 (19.10) | 18.2507 |
| 2000's | 26 (29.21) | 29.6817 |
| 2010's | 14 (15.73) | 24.3611 |
| 2020's | 3 (3.37) | 2.80 |
| Authors | Studies |
|---|---|
| Chawla, RR; Hampton, A; Kappler, F | 1 |
| Andersson, J; Larsson, KM; Logan, DT; Nordlund, P; Sjöberg, BM | 1 |
| Amblard, F; Bassit, L; Bondada, L; Coats, SJ; Detorio, M; Grier, J; Hernandez-Santiago, BI; Koontz, D; Mellors, JW; Rapp, KL; Schinazi, RF; Sluis-Cremer, N | 1 |
| Meanwell, NA | 1 |
| Fuchs, JA; Manwaring, JD | 1 |
| Furman, PA; Hopkins, S; Painter, GR; Wright, LL | 1 |
| Bianchi, V; Pontis, E; Reichard, P | 2 |
| Kwok, JB; Tattersall, MH | 1 |
| Brumley, J; Hayman, RJ; Rose, IS; van der Weyden, MB | 1 |
| Bevan, IS; Day, PJ; Gurney, SJ; Walker, MR; Young, LS | 1 |
| Kornberg, A; O'Donnell, ME | 1 |
| Schroeder, AL; Srivastava, VK | 1 |
| Fyfe, JA; Sherman, PA | 1 |
| Frick, LW; Nelson, DJ | 1 |
| Eriksson, S; Skog, S; Tribukait, B; Wallström, B | 1 |
| Andersson, M; Lewan, L | 1 |
| Lagergren, J; Reichard, P | 1 |
| Carlquist, M; Eriksson, S; Jörnvall, H; Sjöberg, BM | 1 |
| Reichard, P; Söderman, K | 1 |
| Lecomte, P; Ninio, J; Papanicolaou, C | 1 |
| Fox, RM | 1 |
| Bestwick, RK; Mathews, CK; Moffett, GL | 1 |
| Furman, PA; Lambe, CU; Nelson, DJ | 1 |
| Tanaka, K; Tanaka, S; Wataya, Y; Yoshioka, A | 1 |
| Eriksson, S | 1 |
| Biswas, SB; Kornberg, A | 1 |
| Jackson, RC | 1 |
| Ikegami, S; Nagano, H; Okano, K | 1 |
| Daikuhara, Y; Gohda, E; Inoue, H; Kato, Y; Takeda, Y; Takigawa, M | 1 |
| Snyder, RD | 1 |
| Cory, JG; Sato, A | 1 |
| Ganeshaguru, K; Hoffbrand, AV; Lee, N; Piga, A; Prentice, HG; Russell, NH; Smyth, JF | 1 |
| Caras, IW; Martin, DW | 1 |
| Bestwick, RK; Mathews, CK | 1 |
| Benkovic, SJ; Frey, MW; Millar, DP; Sowers, LC | 1 |
| Collins, MK; López-Rivas, A; Marvel, J; Oliver, FJ | 1 |
| Rappaport, HP | 1 |
| Avidan, O; Bakhanashvili, M; Hizi, A | 1 |
| Alur, P; Dornadula, G; Laughlin, MA; Pomerantz, RJ; Zhang, H | 1 |
| Arzumanov, AA; Dyatkina, NB; Gosselin, G; Imbach, JL; Krayevsky, AA; Meyer, A; Rayner, B; Semizarov, DG; Vichier-Guerre, S | 1 |
| Meuth, M | 1 |
| Bielefeldt-Ohmann, H; Fitzpatrick, DR | 1 |
| Fujikawa, K; Kamiya, H; Kasai, H | 1 |
| Bewley, J; Chen, VJ; Gates, SB; Habeck, LL; Mendelsohn, LG; Ray, J; Shackelford, KA; Tonkinson, JL; Toth, JE | 1 |
| Harwood, FG; Houghton, JA; Tillman, DM | 1 |
| Bogue, M; Meek, K; Mickelsen, S; Roth, DB; Snyder, C; Trujillo, K | 1 |
| Kumari, D; Usdin, K | 1 |
| Enger, MD; Gurley, LR; Ratliff, RL; Tobey, RA; Walters, RA | 1 |
| Heeger, P; Mynatt, RL; Truett, AA; Truett, GE; Walker, JA; Warman, ML | 1 |
| Berger, M; McMinn, DL; Ogawa, AK; Romesberg, FE; Schultz, PG; Wu, Y | 1 |
| Ishikawa, F; Saito, M; Saneyoshi, M; Shudo, K; Tomikawa, A; Yamada, R; Yamaguchi, T | 1 |
| Alekseyev, YO; Dzantiev, L; Kool, ET; Morales, JC; Romano, LJ | 1 |
| Amin, S; Geacintov, NE; Kolbanovskiy, A; Zhuang, P | 1 |
| Dunlap, CA; Tsai, MD | 1 |
| Collins, S; Gerard, GF; Smith, MD | 1 |
| Cooperman, BS; Kashlan, OB | 1 |
| Bassett, E; Chaney, SG; Gauger, M; Havener, JM; Nick McElhinny, SA; Ramsden, DA | 1 |
| Eklund, H; Eliasson, R; Färnegårdh, M; Jordan, A; Uhlin, U; Uppsten, M | 1 |
| Mathews, CK; Song, S; Wheeler, LJ | 1 |
| Barroso, JF; Elholm, M; Flatmark, T | 1 |
| Dong, Y; Fiala, KA; Roettger, MP; Sompalli, S; Suo, Z | 1 |
| Konigsberg, W; Wang, J; Yang, G | 1 |
| Hayakawa, H; Ishibashi, T; Ito, R; Sekiguchi, M | 1 |
| Hamby, K; Persson, K; Ugozzoli, LA | 1 |
| Broyde, S; Patel, DJ; Rechkoblit, O; Shapiro, R; Wang, L; Zhang, L | 1 |
| Bernardi, P; Bianchi, V; Ferraro, P; Nicolosi, L; Reichard, P | 1 |
| Boes, C; Fearnley, IM; Harbour, ME; Kunji, ER; Monné, M; Robinson, AJ | 1 |
| Chilkoti, A; Chow, DC | 1 |
| Chi, LM; Lam, SL | 1 |
| Arakawa, H; Kamahori, M; Kambara, H; Karasawa, K; Maeda, M; Munakata, E; Obinata, R; Suzuki, S | 1 |
| Broyde, S; Donny-Clark, K | 1 |
| Radivoyevitch, T | 1 |
| Abdulovic, AL; Chabes, A; Kumar, D; Kunkel, TA; Nilsson, AK; Viberg, J | 1 |
| Christodoulou, E; Crow, YJ; de Carvalho, LP; Ennis-Adeniran, V; Goldstone, DC; Groom, HC; Haire, LF; Hedden, JJ; Kelly, G; Rice, GI; Stoye, JP; Taylor, IA; Walker, PA; Webb, M; Yap, MW | 1 |
| Elber, R; Johnson, KA; Kirmizialtin, S; Nguyen, V | 1 |
| Kore, AR; Senthilvelan, A; Shanmugasundaram, M; Srinivasan, B | 1 |
| Cho, BP; Vaidyanathan, VG; Xu, L | 1 |
| Allen, WJ; Felekyan, S; Kalinin, S; Rothwell, PJ; Seidel, CA; Sisamakis, E; Waksman, G; Widengren, J | 1 |
| Cafarelli, TM; Godoy, VG; Rands, TJ | 1 |
| Fijalkowska, IJ; Gawel, D; Jonczyk, P; Schaaper, RM | 1 |
| Buckland, RJ; Chabes, A; Chittoor, B; Kunkel, TA; Nilsson, AK; Watt, DL | 1 |
| Creech, A; Loechler, EL; Sholder, G | 1 |
| Anderson, PL; Bushman, LR; Castillo-Mancilla, JR; Chen, X; MaWhinney, S; McAllister, KB; Seifert, SM; Zheng, JH | 1 |
| Anderson, PL; Bushman, LR; Chen, X; Klein, B; McAllister, KJ | 1 |
| Wetmore, SD; Wilson, KA | 1 |
| Chang, ZF; González-Pacanowska, D; Huang, CY; Yagüe-Capilla, M | 1 |
| Calcuttawala, F; Das Gupta, SK; Ghosh, S; Mukherjee, N; Patra, MM; Sarkar, A; Shaw, R | 1 |
| Dubovskaja, V; Jasponė, A; Kapustina, Ž; Lubys, A; Mackevičius, G | 1 |
2 review(s) available for thymidine 5'-triphosphate and 2'-deoxyadenosine triphosphate
| Article | Year |
|---|---|
Changes in deoxynucleoside triphosphate pools induced by inhibitors and modulators of ribonucleotide reductase.
Topics: Animals; Aziridines; Cells, Cultured; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; Humans; Hydroxyurea; Ribonucleotide Reductases; Substrate Specificity; T-Lymphocytes; Thiosemicarbazones; Thymine Nucleotides | 1985 |
A kinetic model of regulation of the deoxyribonucleoside triphosphate pool composition.
Topics: Animals; Antimetabolites; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleosides; Deoxyribonucleotides; DNA; Humans; Kinetics; Liver Neoplasms, Experimental; Models, Biological; Nucleic Acid Synthesis Inhibitors; Ribonucleoside Diphosphate Reductase; Thermodynamics; Thymidylate Synthase; Thymine Nucleotides | 1984 |
1 trial(s) available for thymidine 5'-triphosphate and 2'-deoxyadenosine triphosphate
| Article | Year |
|---|---|
Analysis of the Endogenous Deoxynucleoside Triphosphate Pool in HIV-Positive and -Negative Individuals Receiving Tenofovir-Emtricitabine.
Topics: Adult; Anti-HIV Agents; Case-Control Studies; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Emtricitabine; Female; HIV Infections; HIV-1; Humans; Leukocytes, Mononuclear; Linear Models; Male; Tenofovir; Thymine Nucleotides | 2016 |
86 other study(ies) available for thymidine 5'-triphosphate and 2'-deoxyadenosine triphosphate
| Article | Year |
|---|---|
Design of species- or isozyme-specific enzyme inhibitors. 1. Effect of thymidine substituents on affinity for the thymidine site of hamster cytoplasmic thymidine kinase.
Topics: Animals; Cricetinae; Cytoplasm; Deoxycytidine; Deoxyuridine; Humans; In Vitro Techniques; Isoenzymes; Kidney; Kinetics; Methods; Mitochondria; Structure-Activity Relationship; Substrate Specificity; Thymidine; Thymidine Kinase; Thymine Nucleotides | 1979 |
Structural basis for allosteric substrate specificity regulation in anaerobic ribonucleotide reductases.
Topics: Allosteric Site; Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Deoxyribonucleotides; Evolution, Molecular; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Polyphosphates; Protein Binding; Protein Conformation; Ribonucleotide Reductases; Sequence Homology, Amino Acid; Substrate Specificity | 2001 |
Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides.
Topics: Anti-HIV Agents; Cell Line, Tumor; Cell Survival; Cells, Cultured; Dideoxynucleosides; HIV Infections; HIV-1; Humans; Molecular Structure; Reverse Transcriptase Inhibitors | 2009 |
Synopsis of some recent tactical application of bioisosteres in drug design.
Topics: Cytochrome P-450 Enzyme System; Drug Design | 2011 |
Nucleoside triphosphate pools in minicells of Escherichia coli.
Topics: Adenosine Triphosphate; Cytidine Triphosphate; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Escherichia coli; Guanosine Triphosphate; Nucleotides; Thymine Nucleotides; Uridine Triphosphate | 1977 |
Initial binding of 2'-deoxynucleoside 5'-triphosphates to human immunodeficiency virus type 1 reverse transcriptase.
Topics: Binding, Competitive; Catalysis; Deoxyadenine Nucleotides; Fluorescence Polarization; HIV-1; Kinetics; Osmolar Concentration; Plasmids; RNA-Directed DNA Polymerase; Thymine Nucleotides; Tryptophan | 1991 |
Dynamics of the dATP pool in cultured mammalian cells.
Topics: 3T3 Cells; Adenine; Animals; Aphidicolin; Cell Line; Cytarabine; Deoxyadenine Nucleotides; Deoxyadenosines; DNA; Hypoxanthine; Hypoxanthines; Kinetics; Mice; Pentostatin; Substrate Cycling; Thymine Nucleotides | 1992 |
Inhibition of 2-desamino-2-methyl-10-propagyl-5,8-dideazafolic acid cytotoxicity by 5,10-dideazatetrahydrofolate in L1210 cells with decrease in DNA fragmentation and deoxyadenosine triphosphate pools.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Survival; Deoxyadenine Nucleotides; DNA, Neoplasm; Drug Antagonism; Folic Acid; Folic Acid Antagonists; Hypoxanthine; Hypoxanthines; Leukemia L1210; Mice; Tetrahydrofolates; Thymine Nucleotides; Tumor Cells, Cultured | 1991 |
Folate-deficient human lymphoblasts: changes in deoxynucleotide metabolism and thymidylate cycle activities.
Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyuridine; Dose-Response Relationship, Drug; Folic Acid; Folic Acid Deficiency; Humans; Lymphocyte Activation; Lymphocytes; Nucleotides; Thymidine; Thymidylate Synthase; Thymine Nucleotides | 1991 |
Synthesis in vitro and application of biotinylated DNA probes for human papilloma virus type 16 by utilizing the polymerase chain reaction.
Topics: Base Sequence; Biotin; Deoxyadenine Nucleotides; Deoxyuracil Nucleotides; DNA Probes; DNA, Viral; Gene Amplification; Molecular Sequence Data; Nucleic Acid Hybridization; Papillomaviridae; Polymerase Chain Reaction; Thymine Nucleotides | 1990 |
Dynamics of DNA polymerase III holoenzyme of Escherichia coli in replication of a multiprimed template.
Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Bacteriophage phi X 174; Base Composition; Deoxyadenine Nucleotides; Deoxyribonucleotides; DNA Polymerase III; DNA Replication; DNA Restriction Enzymes; DNA-Directed DNA Polymerase; DNA, Circular; DNA, Single-Stranded; DNA, Viral; Escherichia coli; Kinetics; Nucleic Acid Hybridization; RNA; Templates, Genetic; Thymine Nucleotides | 1985 |
Deoxyribonucleoside triphosphate pools in mutagen sensitive mutants of Neurospora crassa.
Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA, Fungal; Genes, Fungal; Histidine; Hydroxyurea; Mutation; Neurospora; Neurospora crassa; Thymine Nucleotides | 1989 |
Enzymatic assay for deoxyribonucleoside triphosphates using synthetic oligonucleotides as template primers.
Topics: Base Sequence; Cells, Cultured; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA-Directed DNA Polymerase; Humans; Micrococcus; Oligonucleotides; Perchlorates; Poly dA-dT; Reference Standards; Templates, Genetic; Thymine Nucleotides; Tritium | 1989 |
Effects of 3'-azido-3'-deoxythymidine on the deoxynucleoside triphosphate pools of cultured human cells.
Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Dose-Response Relationship, Drug; Humans; Nucleoside-Phosphate Kinase; Thymine Nucleotides; Tumor Cells, Cultured; Zidovudine | 1989 |
Deoxyribonucleoside triphosphate metabolism and the mammalian cell cycle. Effects of hydroxyurea on mutant and wild-type mouse S49 T-lymphoma cells.
Topics: Animals; Cell Cycle; Cell Line; Deoxyadenine Nucleotides; Deoxycytidine Kinase; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; Hydroxyurea; Lymphoma; Mice; Mutation; Purine-Nucleoside Phosphorylase; Ribonucleotide Reductases; T-Lymphocytes; Thymidine Kinase; Thymine Nucleotides | 1987 |
Early increase in diadenosine tetraphosphate in regenerating rat liver.
Topics: Adenine Nucleotides; Animals; Cell Division; Chromatography, High Pressure Liquid; Deoxyadenine Nucleotides; Dinucleoside Phosphates; DNA; Liver; Liver Regeneration; Male; Rats; Rats, Inbred Strains; Thymine Nucleotides; Uridine Triphosphate | 1988 |
Purine deoxyribonucleosides counteract effects of hydroxyurea on deoxyribonucleoside triphosphate pools and DNA synthesis.
Topics: Animals; Cell Line; Cricetinae; Deoxyadenine Nucleotides; Deoxyadenosines; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyguanosine; DNA; Hydroxyurea; Nucleotides; Purine Nucleosides; Thymine Nucleotides | 1987 |
A photoaffinity-labeled allosteric site in Escherichia coli ribonucleotide reductase.
Topics: Adenosine Triphosphate; Affinity Labels; Allosteric Regulation; Allosteric Site; Amino Acid Sequence; Bacterial Proteins; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Chromatography, Thin Layer; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; Escherichia coli; Peptides; Ribonucleotide Reductases; Thymine Nucleotides | 1986 |
A nitrocellulose filter binding assay for ribonucleotide reductase.
Topics: Binding Sites; Binding, Competitive; Collodion; Deoxyadenine Nucleotides; Dialysis; Filtration; Protein Binding; Ribonucleotide Reductases; Thymine Nucleotides | 1986 |
Changes of deoxyribonucleoside triphosphate pools induced by hydroxyurea and their relation to DNA synthesis.
Topics: Cells, Cultured; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA; Hydroxyurea; Ribonucleotide Reductases; Thymine Nucleotides | 1986 |
Mnemonic aspects of Escherichia coli DNA polymerase I. Interaction with one template influences the next interaction with another template.
Topics: Base Composition; Deoxyadenine Nucleotides; Deoxycytidine Monophosphate; Deoxyguanine Nucleotides; DNA Polymerase I; DNA Replication; Escherichia coli; Kinetics; Models, Biological; Poly dA-dT; Templates, Genetic; Thymine Nucleotides | 1986 |
Selective expansion of mitochondrial nucleoside triphosphate pools in antimetabolite-treated HeLa cells.
Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA; Floxuridine; HeLa Cells; Humans; Methotrexate; Mitochondria; Ribonucleotides; Thymine Nucleotides | 1982 |
Effect of acyclovir on the deoxyribonucleoside triphosphate pool levels in Vero cells infected with herpes simplex virus type 1.
Topics: Acyclovir; Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; Guanine; Phosphonoacetic Acid; Simplexvirus; Thymine Nucleotides | 1982 |
An improved method for the quantitative determination of deoxyribonucleoside triphosphates in cell extracts.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Extracts; Chromatography, High Pressure Liquid; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; Male; Methylamines; Mice; Oxidation-Reduction; Periodic Acid; Ribonucleotides; Thymine Nucleotides; Tissue Extracts | 1984 |
Direct photoaffinity labeling of ribonucleotide reductase from Escherichia coli. Evidence for enhanced binding of the allosteric effector dTTP by the presence of substrates.
Topics: Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; Escherichia coli; Guanosine Diphosphate; Macromolecular Substances; Photochemistry; Ribonucleotide Reductases; Thymine Nucleotides | 1983 |
Nucleoside triphosphate binding to DNA polymerase III holoenzyme of Escherichia coli. A direct photoaffinity labeling study.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Binding Sites; Deoxyadenine Nucleotides; DNA Polymerase III; DNA-Directed DNA Polymerase; Escherichia coli; Photochemistry; Thionucleotides; Thymine Nucleotides; Ultraviolet Rays | 1984 |
Changes in deoxyribonucleoside triphosphate pools in the starfish oocyte during maturation and early embryogenesis.
Topics: Animals; Aphidicolin; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; Diterpenes; Female; Oocytes; Oogenesis; Ovum; Starfish; Thymine Nucleotides; Zygote | 1983 |
Inhibition of polyamine synthesis and proliferation in mouse L cells by DL-alpha-hydrazino-delta-aminovaleric acid, an inhibitor of ornithine decarboxylase.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; Deoxyadenine Nucleotides; DNA; L Cells; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Thymine Nucleotides | 1983 |
Deoxyribonucleoside triphosphate pools in human diploid fibroblasts and their modulation by hydroxyurea and deoxynucleosides.
Topics: Cells, Cultured; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleosides; Deoxyribonucleotides; Diploidy; Fibroblasts; Humans; Hydroxyurea; Thymine Nucleotides | 1984 |
Evaluation of combinations of drugs that inhibit Ehrlich tumor cell ribonucleotide reductase.
Topics: Aldehydes; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; Drug Interactions; Drug Synergism; Edetic Acid; Hydroxyurea; Imidazoles; Inosine; Isoquinolines; Mice; Pyrazoles; Ribonucleotide Reductases; Thiosemicarbazones; Thymine Nucleotides | 1981 |
Studies on the biochemical sequelae of therapy in Thy-acute lymphoblastic leukaemia with the adenosine deaminase inhibitor 2' deoxycoformycin.
Topics: Adenosine Deaminase; Adenosylhomocysteinase; Adolescent; Adult; Bone Marrow; Coformycin; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Humans; Hydrolases; Leukemia, Lymphoid; Leukocyte Count; Male; Pentostatin; Ribonucleosides; Thymine Nucleotides | 1981 |
Direct photoaffinity labeling of an allosteric site of subunit protein M1 of mouse ribonucleotide reductase by dATP. Evidence for two independent binding interactions within the allosteric specificity site.
Topics: Affinity Labels; Allosteric Site; Animals; Binding Sites; Binding, Competitive; Cell Line; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; Lymphoma, Non-Hodgkin; Mice; Mutation; Neoplasms, Experimental; Ribonucleotide Reductases; Thymine Nucleotides; Ultraviolet Rays | 1982 |
Unusual compartmentation of precursors for nuclear and mitochondrial DNA in mouse L cells.
Topics: Animals; Cell Compartmentation; Cell Nucleus; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA; L Cells; Mice; Mitochondria; Phosphorus Radioisotopes; Thymine Nucleotides; Tritium; Uridine | 1982 |
The nucleotide analog 2-aminopurine as a spectroscopic probe of nucleotide incorporation by the Klenow fragment of Escherichia coli polymerase I and bacteriophage T4 DNA polymerase.
Topics: 2-Aminopurine; Bacteriophage T4; Base Sequence; Deoxyadenine Nucleotides; Deoxyribonucleotides; DNA; DNA Polymerase I; DNA-Directed DNA Polymerase; Escherichia coli; Fluorescent Dyes; Kinetics; Molecular Sequence Data; Spectrometry, Fluorescence; Substrate Specificity; Thymine Nucleotides; Viral Proteins | 1995 |
Bcl-2 oncogene protects a bone marrow-derived pre-B-cell line from 5'-fluor,2'-deoxyuridine-induced apoptosis.
Topics: Animals; Apoptosis; B-Lymphocytes; Cell Line; Cell Survival; Deoxyadenine Nucleotides; Dose-Response Relationship, Drug; Floxuridine; Hematopoietic Stem Cells; Humans; Kinetics; Mice; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogenes; Thymine Nucleotides; Transfection | 1993 |
Replication of the base pair 6-thioguanine/5-methyl-2-pyrimidine with the large Klenow fragment of Escherichia coli DNA polymerase I.
Topics: Base Composition; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; DNA Polymerase I; DNA Replication; Escherichia coli; Exodeoxyribonuclease V; Exodeoxyribonucleases; Kinetics; Mathematics; Models, Biological; Pyrimidinones; Templates, Genetic; Thioguanine; Thymine Nucleotides | 1993 |
Mutational studies of human immunodeficiency virus type 1 reverse transcriptase: the involvement of residues 183 and 184 in the fidelity of DNA synthesis.
Topics: Base Sequence; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA Replication; DNA, Viral; Electrophoresis, Polyacrylamide Gel; HIV Reverse Transcriptase; HIV-1; Humans; Kinetics; Molecular Sequence Data; Mutation; RNA-Directed DNA Polymerase; Thymine Nucleotides | 1996 |
Amphipathic domains in the C terminus of the transmembrane protein (gp41) permeabilize HIV-1 virions: a molecular mechanism underlying natural endogenous reverse transcription.
Topics: Animals; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; HIV Envelope Protein gp41; HIV Reverse Transcriptase; HIV-1; Humans; Mice; Permeability; Rats; Thymine Nucleotides; Transcription, Genetic; Virion | 1996 |
Stereoisomers of deoxynucleoside 5'-triphosphates as substrates for template-dependent and -independent DNA polymerases.
Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; DNA Primers; DNA-Directed DNA Polymerase; Electrophoresis, Polyacrylamide Gel; HIV Reverse Transcriptase; Humans; Stereoisomerism; Structure-Activity Relationship; Templates, Genetic; Thymine Nucleotides | 1997 |
Sensitivity of a mutator gene in Chinese hamster ovary cell to deoxynucleoside triphosphate pool alterations.
Topics: Animals; CHO Cells; Cricetinae; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Emetine; Female; Mutation; Ovary; Protein Synthesis Inhibitors; Thymidine; Thymine Nucleotides | 1981 |
High-efficiency T-vector cloning of PCR products by forced A tagging and post-ligation restriction enzyme digestion.
Topics: Cloning, Molecular; Deoxyadenine Nucleotides; Deoxyribonucleases, Type II Site-Specific; DNA Ligases; DNA Primers; Escherichia coli; Genetic Vectors; Polymerase Chain Reaction; Taq Polymerase; Thymine Nucleotides | 1997 |
The mutations induced by oxidatively damaged nucleotides, 5-formyl-dUTP and 5-hydroxy-dCTP,in Escherichia coli.
Topics: Bacterial Proteins; Deoxyadenine Nucleotides; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyuracil Nucleotides; Deoxyuridine; DNA Mutational Analysis; DNA Repair; Escherichia coli; Escherichia coli Proteins; Genome, Bacterial; Lac Repressors; Models, Genetic; Mutagenesis; Nucleic Acid Hybridization; Oxidants; Point Mutation; Repressor Proteins; Sequence Analysis, DNA; Thymine Nucleotides | 1998 |
The antiproliferative and cell cycle effects of 5,6,7, 8-tetrahydro-N5,N10-carbonylfolic acid, an inhibitor of methylenetetrahydrofolate dehydrogenase, are potentiated by hypoxanthine.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Division; Deoxyadenine Nucleotides; Drug Synergism; Enzyme Inhibitors; Folic Acid; Humans; Hypoxanthine; Methylenetetrahydrofolate Dehydrogenase (NADP); Thymine Nucleotides; Tumor Cells, Cultured | 1998 |
Ratio of 2'-deoxyadenosine-5'-triphosphate/thymidine-5'-triphosphate influences the commitment of human colon carcinoma cells to thymineless death.
Topics: Cell Death; Cell Survival; Clone Cells; Deoxyadenine Nucleotides; Deoxyadenosines; Fluorouracil; Humans; Kinetics; Leucovorin; Nucleosomes; Thymine; Thymine Nucleotides; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1995 |
Modulation of terminal deoxynucleotidyltransferase activity by the DNA-dependent protein kinase.
Topics: Animals; Catalysis; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA Nucleotidylexotransferase; DNA-Activated Protein Kinase; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Humans; Mice; Mice, SCID; Nuclear Proteins; Oligonucleotides; Protein Serine-Threonine Kinases; Substrate Specificity; Thymine Nucleotides; Tumor Cells, Cultured | 1999 |
Sequencing errors in reactions using labeled terminators.
Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Dideoxyadenosine; DNA Primers; DNA-Directed DNA Polymerase; Inosine Triphosphate; Polymerase Chain Reaction; Potassium Chloride; Quality Control; Sensitivity and Specificity; Sequence Analysis, DNA; Templates, Genetic; Thymine Nucleotides | 1999 |
Effects of X-irradiation on DNA precursor metabolism and deoxyribonucleoside triphosphate pools in Chinese hamster cells.
Topics: Animals; CHO Cells; Cricetinae; Cytidine; Deoxyadenine Nucleotides; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA Damage; DNA Repair; DNA Replication; Dose-Response Relationship, Radiation; Intracellular Fluid; RNA; S Phase; Thymidine; Thymine Nucleotides | 1974 |
Preparation of PCR-quality mouse genomic DNA with hot sodium hydroxide and tris (HotSHOT).
Topics: Aging; Animals; Buffers; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA; Hot Temperature; Hydrogen-Ion Concentration; Indicators and Reagents; Magnesium Chloride; Mice; Polymerase Chain Reaction; Sodium Hydroxide; Solubility; Taq Polymerase; Thymine Nucleotides | 2000 |
Universal bases for hybridization, replication and chain termination.
Topics: Base Pairing; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; DNA; DNA Replication; DNA-Directed DNA Polymerase; Drug Stability; Hot Temperature; Hydrogen Bonding; Isoquinolines; Methylation; Nucleic Acid Hybridization; Nucleosides; Oligonucleotides; Substrate Specificity; Templates, Genetic; Thymine Nucleotides | 2000 |
Recognition of 2'-deoxy-l-ribonucleoside 5'-triphosphates by human telomerase.
Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; Humans; Kinetics; Stereoisomerism; Substrate Specificity; Telomerase; Thymine Nucleotides | 2000 |
Significance of nucleobase shape complementarity and hydrogen bonding in the formation and stability of the closed polymerase-DNA complex.
Topics: Base Composition; Base Pairing; Deoxyadenine Nucleotides; Deoxyribonucleotides; DNA; DNA Polymerase I; DNA Primers; Enzyme Stability; Hydrogen Bonding; Nucleic Acid Conformation; Nucleotides; Pyrenes; Ribonucleotides; Templates, Genetic; Thymine Nucleotides; Toluene | 2001 |
Base sequence dependence of in vitro translesional DNA replication past a bulky lesion catalyzed by the exo- Klenow fragment of Pol I.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Base Sequence; Carcinogens, Environmental; Catalysis; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyguanosine; DNA Damage; DNA Polymerase I; DNA Primers; DNA Replication; Guanine; Kinetics; Mutagenesis; Mutagens; Polydeoxyribonucleotides; Pyrimidine Nucleotides; Sequence Analysis, DNA; Templates, Genetic; Thymine Nucleotides | 2001 |
Use of 2-aminopurine and tryptophan fluorescence as probes in kinetic analyses of DNA polymerase beta.
Topics: 2-Aminopurine; Animals; Catalysis; Cations, Divalent; Deoxyadenine Nucleotides; Diphosphates; DNA Polymerase beta; DNA Probes; Kinetics; Magnesium; Rats; Spectrometry, Fluorescence; Substrate Specificity; Templates, Genetic; Thymine Nucleotides; Tryptophan | 2002 |
Excess dNTPs minimize RNA hydrolysis during reverse transcription.
Topics: Avian Sarcoma Viruses; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA, Complementary; Drug Stability; Electrophoresis, Agar Gel; Half-Life; Hot Temperature; Hydrolysis; Magnesium; Moloney murine leukemia virus; Nucleic Acid Denaturation; RNA; RNA-Directed DNA Polymerase; Thymine Nucleotides; Transcription, Genetic; Viral Proteins | 2002 |
Comprehensive model for allosteric regulation of mammalian ribonucleotide reductase: refinements and consequences.
Topics: Adenosine Triphosphate; Allosteric Regulation; Animals; Asparagine; Aspartic Acid; Cytidine Diphosphate; Deoxyadenine Nucleotides; Dimerization; Enzyme Activation; Guanosine Diphosphate; Kinetics; Light; Magnesium; Mice; Models, Chemical; Mutagenesis, Site-Directed; Protein Subunits; Recombinant Proteins; Ribonucleoside Diphosphate Reductase; Ribonucleotide Reductases; Scattering, Radiation; Substrate Specificity; Thymine Nucleotides; Tumor Cells, Cultured | 2003 |
Translesion synthesis past platinum DNA adducts by human DNA polymerase mu.
Topics: Catalysis; Cisplatin; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; DNA Adducts; DNA Damage; DNA Primers; DNA-Directed DNA Polymerase; DNA, Single-Stranded; Guanine Nucleotides; Humans; Oligonucleotides; Organoplatinum Compounds; Oxaliplatin; Templates, Genetic; Thymine Nucleotides | 2003 |
Structure of the large subunit of class Ib ribonucleotide reductase from Salmonella typhimurium and its complexes with allosteric effectors.
Topics: Allosteric Regulation; Allosteric Site; Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Cysteine; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Dimerization; Escherichia coli; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Protein Conformation; Protein Subunits; Ribonucleotide Reductases; Salmonella typhimurium; Sequence Homology, Amino Acid; Thymine Nucleotides | 2003 |
Deoxyribonucleotide pool imbalance stimulates deletions in HeLa cell mitochondrial DNA.
Topics: Base Pairing; Blotting, Southern; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA, Mitochondrial; Gastrointestinal Diseases; Gene Deletion; HeLa Cells; Humans; Mitochondria; Mitochondrial Encephalomyopathies; Point Mutation; Polymerase Chain Reaction; Thymidine; Thymine Nucleotides | 2003 |
Tight binding of deoxyribonucleotide triphosphates to human thymidine kinase 2 expressed in Escherichia coli. Purification and partial characterization of its dimeric and tetrameric forms.
Topics: Binding Sites; Cell Line, Tumor; Chaperonin 10; Chaperonin 60; Cloning, Molecular; Culture Media, Conditioned; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Dimerization; Enzyme Inhibitors; Escherichia coli; Ethanol; Humans; Isoenzymes; Kinetics; Models, Molecular; Recombinant Fusion Proteins; Solubility; Spectrometry, Fluorescence; Substrate Specificity; Thymidine Kinase; Thymine Nucleotides; Tryptophan | 2003 |
Pre-steady-state kinetic studies of the fidelity of human DNA polymerase mu.
Topics: Binding Sites; Buffers; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA; DNA Nucleotidylexotransferase; DNA Primers; DNA-Directed DNA Polymerase; Enzyme Activation; Enzyme Stability; Humans; Kinetics; Peptide Chain Elongation, Translational; Ribonucleotides; Substrate Specificity; Templates, Genetic; Thymine Nucleotides; Uridine Triphosphate | 2004 |
Base selectivity is impaired by mutants that perturb hydrogen bonding networks in the RB69 DNA polymerase active site.
Topics: Alanine; Amino Acid Substitution; Base Pair Mismatch; Binding Sites; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA-Directed DNA Polymerase; Enterobacter; Hydrogen Bonding; Kinetics; Nucleotides; Phenylalanine; Substrate Specificity; Thymine Nucleotides; Toluene; Tyrosine; Viral Proteins | 2005 |
Multiple enzyme activities of Escherichia coli MutT protein for sanitization of DNA and RNA precursor pools.
Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA Replication; DNA, Bacterial; Escherichia coli Proteins; Guanine; Guanosine Triphosphate; Hydrolysis; Kinetics; Multienzyme Complexes; Phosphoric Monoester Hydrolases; Pyrophosphatases; RNA, Bacterial; Thymine Nucleotides; Transcription, Genetic | 2005 |
Four-color multiplex reverse transcription polymerase chain reaction--overcoming its limitations.
Topics: Color; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA Primers; DNA Probes; DNA, Complementary; Gene Expression; Reverse Transcriptase Polymerase Chain Reaction; Taq Polymerase; Thymine Nucleotides | 2005 |
Mutagenic nucleotide incorporation and hindered translocation by a food carcinogen C8-dG adduct in Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): modeling and dynamics studies.
Topics: Binding Sites; Carcinogens; Computational Biology; Computer Simulation; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyguanosine; Deoxyribonucleotides; DNA; DNA Adducts; DNA Polymerase beta; Imidazoles; Models, Molecular; Motion; Mutagenesis; Nucleic Acid Conformation; Sulfolobus solfataricus; Thymine Nucleotides | 2006 |
Mitochondrial deoxynucleotide pool sizes in mouse liver and evidence for a transport mechanism for thymidine monophosphate.
Topics: Animals; Biological Transport, Active; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyuracil Nucleotides; Male; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Thymidine Monophosphate; Thymine Nucleotides | 2006 |
The mimivirus genome encodes a mitochondrial carrier that transports dATP and dTTP.
Topics: Amino Acid Sequence; Animals; Biological Transport; Cattle; Deoxyadenine Nucleotides; DNA Viruses; Genome, Viral; Humans; Lactococcus lactis; Mitochondria; Molecular Sequence Data; Sequence Alignment; Thymine Nucleotides | 2007 |
Surface-initiated enzymatic polymerization of DNA.
Topics: Antibodies; Antibody Specificity; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; DNA Nucleotidylexotransferase; DNA, Single-Stranded; Microscopy, Atomic Force; Nanotechnology; Oligonucleotides; Polydeoxyribonucleotides; Spectrometry, X-Ray Emission; Surface Plasmon Resonance; Surface Properties; Thymine Nucleotides; Time Factors | 2007 |
Nuclear magnetic resonance investigation of primer--template models: formation of a pyrimidine bulge upon misincorporation.
Topics: Adenine; Base Pair Mismatch; Base Pairing; Cytosine; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; DNA Primers; DNA Replication; Guanine; Models, Genetic; Nuclear Magnetic Resonance, Biomolecular; Templates, Genetic; Thymidine; Thymine Nucleotides | 2008 |
Development of bioluminescent pyrophosphate assay using pyruvate phosphate dikinase and its application to single-nucleotide polymorphism analysis.
Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Diphosphates; DNA; Luciferases; Luminescent Measurements; Models, Biological; Polymorphism, Single Nucleotide; Pyruvate, Orthophosphate Dikinase; ras Proteins; Reproducibility of Results; Thionucleotides; Thymine Nucleotides; Tumor Suppressor Protein p53 | 2008 |
Influence of local sequence context on damaged base conformation in human DNA polymerase iota: molecular dynamics studies of nucleotide incorporation opposite a benzo[a]pyrene-derived adenine lesion.
Topics: Base Pair Mismatch; Base Pairing; Base Sequence; Benzopyrenes; Carcinogens, Environmental; Computer Simulation; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA Adducts; DNA Damage; DNA Polymerase iota; DNA-Directed DNA Polymerase; Humans; Hydrogen Bonding; Magnesium; Models, Molecular; Nucleic Acid Conformation; Thymine Nucleotides | 2009 |
Automated mass action model space generation and analysis methods for two-reactant combinatorially complex equilibriums: an analysis of ATP-induced ribonucleotide reductase R1 hexamerization data.
Topics: Adenosine Triphosphate; Catalytic Domain; Computer Simulation; Deoxyadenine Nucleotides; Deoxyguanine Nucleotides; Humans; Least-Squares Analysis; Models, Biological; Nonlinear Dynamics; Protein Multimerization; Protein Subunits; Ribonucleotide Reductases; Substrate Specificity; Thymine Nucleotides | 2009 |
Mechanisms of mutagenesis in vivo due to imbalanced dNTP pools.
Topics: Amino Acid Substitution; Amino Acid Transport Systems, Basic; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; INDEL Mutation; Mutagenesis; Mutation; Ribonucleotide Reductases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thymine Nucleotides | 2011 |
HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase.
Topics: Allosteric Regulation; Biocatalysis; Catalytic Domain; Crystallography, X-Ray; Dendritic Cells; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; HIV-1; Humans; Hydrolysis; Models, Biological; Models, Molecular; Monomeric GTP-Binding Proteins; Myeloid Cells; Nucleoside-Triphosphatase; Protein Structure, Tertiary; Reverse Transcription; SAM Domain and HD Domain-Containing Protein 1; Thymine Nucleotides; Viral Regulatory and Accessory Proteins; Virus Replication | 2011 |
How conformational dynamics of DNA polymerase select correct substrates: experiments and simulations.
Topics: Algorithms; Catalytic Domain; Deoxyadenine Nucleotides; DNA; HIV Reverse Transcriptase; Humans; Kinetics; Molecular Dynamics Simulation; Probability; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Subunits; Solutions; Thermodynamics; Thymine Nucleotides; Time Factors | 2012 |
Gram-scale chemical synthesis of 2'-deoxynucleoside-5'-o-triphosphates.
Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Diphosphates; Hydrolysis; Nucleosides; Purine Nucleotides; Pyrimidine Nucleotides; Thymine Nucleotides | 2012 |
Binary and ternary binding affinities between exonuclease-deficient Klenow fragment (Kf-exo(-)) and various arylamine DNA lesions characterized by surface plasmon resonance.
Topics: 2-Acetylaminofluorene; Aminobiphenyl Compounds; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA; DNA Adducts; DNA Polymerase I; Fluorenes; Kinetics; Surface Plasmon Resonance; Thymine Nucleotides | 2012 |
dNTP-dependent conformational transitions in the fingers subdomain of Klentaq1 DNA polymerase: insights into the role of the "nucleotide-binding" state.
Topics: Bacterial Proteins; Catalytic Domain; Deoxyadenine Nucleotides; DNA Polymerase I; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Hydrazines; Kinetics; Models, Molecular; Protein Binding; Staining and Labeling; Substrate Specificity; Thermus; Thymine Nucleotides | 2013 |
The DinB•RecA complex of Escherichia coli mediates an efficient and high-fidelity response to ubiquitous alkylation lesions.
Topics: Adenine; Alkylation; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA Adducts; DNA Replication; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Kinetics; Mutagenesis; Rec A Recombinases; Thymine Nucleotides | 2014 |
Effect of dNTP pool alterations on fidelity of leading and lagging strand DNA replication in E. coli.
Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA Replication; Escherichia coli; Lac Operon; Thymine Nucleotides | 2014 |
Increased and imbalanced dNTP pools symmetrically promote both leading and lagging strand replication infidelity.
Topics: Base Pair Mismatch; Base Sequence; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA Mismatch Repair; DNA Replication; Genomic Instability; Molecular Sequence Data; Mutagenesis; Mutation Rate; Organisms, Genetically Modified; Saccharomyces cerevisiae; Thymine Nucleotides | 2014 |
How Y-Family DNA polymerase IV is more accurate than Dpo4 at dCTP insertion opposite an N2-dG adduct of benzo[a]pyrene.
Topics: Archaeal Proteins; Benzo(a)pyrene; Benzopyrenes; Carcinogens, Environmental; Catalytic Domain; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanosine; DNA Polymerase beta; Escherichia coli; Escherichia coli Proteins; Mutagens; Sulfolobus solfataricus; Thymine Nucleotides | 2015 |
Development and validation of an LC-MS/MS quantitative method for endogenous deoxynucleoside triphosphates in cellular lysate.
Topics: Chromatography, Liquid; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Tandem Mass Spectrometry; Thymine Nucleotides | 2017 |
Molecular Insights into the Translesion Synthesis of Benzyl-Guanine from Molecular Dynamics Simulations: Structural Evidence of Mutagenic and Nonmutagenic Replication.
Topics: Benzyl Compounds; Catalytic Domain; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA Adducts; DNA Damage; DNA Polymerase beta; DNA Repair; DNA Replication; Escherichia coli; Escherichia coli Proteins; Guanine; Hydrogen Bonding; Molecular Dynamics Simulation; Mutagenesis; Protein Structure, Secondary; Protein Structure, Tertiary; Thymine Nucleotides | 2017 |
Quantitation of deoxynucleoside triphosphates by click reactions.
Topics: Click Chemistry; Copper; Cycloaddition Reaction; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; Deoxyuracil Nucleotides; HCT116 Cells; HEK293 Cells; Humans; K562 Cells; Rhodamines; Staining and Labeling; Thymine Nucleotides | 2020 |
Mycobacterium tuberculosis thymidylate synthase (ThyX) is a target for plumbagin, a natural product with antimycobacterial activity.
Topics: Antitubercular Agents; Biological Products; Cell Survival; Deoxyadenine Nucleotides; Mycobacterium tuberculosis; Naphthoquinones; Thymidylate Synthase; Thymine Nucleotides | 2020 |
Enzymatic Synthesis of Chimeric DNA Oligonucleotides by
Topics: Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; DNA-Directed RNA Polymerases; Fluorine; Substrate Specificity; Synthetic Biology; Thymine Nucleotides; Transcription, Genetic; Viral Proteins | 2021 |