thuggacin-b and 3-hydroxybutanal

thuggacin-b has been researched along with 3-hydroxybutanal* in 1 studies

Other Studies

1 other study(ies) available for thuggacin-b and 3-hydroxybutanal

ArticleYear
Direct aldol strategy in enantioselective total synthesis of thuggacin B.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2014, Jan-03, Volume: 20, Issue:1

    An enantioselective total synthesis of thuggacin B, a natural product exhibiting antibiotic activity against Mycobacterium tuberculosis, is described. Asymmetric direct aldol reactions promoted by Cu and Zn catalysts play a pivotal role in constructing four stereogenic centers. The use of direct aldol reactions as the initial steps for the synthesis of two key fragments allowed the construction of the other stereogenic centers through chirality transfer.

    Topics: Aldehydes; Antitubercular Agents; Catalysis; Copper; Macrolides; Mycobacterium tuberculosis; Stereoisomerism; Thioamides; Zinc

2014