thromboxanes has been researched along with ibuprofen in 36 studies
| Studies (thromboxanes) | Trials (thromboxanes) | Recent Studies (post-2010) (thromboxanes) | Studies (ibuprofen) | Trials (ibuprofen) | Recent Studies (post-2010) (ibuprofen) |
|---|---|---|---|---|---|
| 3,202 | 149 | 199 | 10,245 | 1,781 | 4,267 |
| Protein | Taxonomy | thromboxanes (IC50) | ibuprofen (IC50) |
|---|---|---|---|
| Prostaglandin G/H synthase 1 | Bos taurus (cattle) | 2.9 | |
| Prostaglandin G/H synthase 2 | Bos taurus (cattle) | 1.1 | |
| Albumin | Bos taurus (cattle) | 3 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 4.0919 | |
| Prostaglandin G/H synthase 1 | Mus musculus (house mouse) | 0.22 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 1.6273 | |
| Caspase-1 | Homo sapiens (human) | 7.2667 | |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | 1.1 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 3.0687 | |
| Prostaglandin G/H synthase 2 | Rattus norvegicus (Norway rat) | 1.3 | |
| Aldo-keto reductase family 1 member C3 | Homo sapiens (human) | 10 | |
| Caspase-3 | Homo sapiens (human) | 7.2667 | |
| Caspase-4 | Homo sapiens (human) | 7.2667 | |
| 4-aminobutyrate aminotransferase, mitochondrial | Rattus norvegicus (Norway rat) | 1.1 | |
| Caspase-5 | Homo sapiens (human) | 7.2667 | |
| Caspase-9 | Homo sapiens (human) | 7.2667 | |
| Prostaglandin G/H synthase 2 | Ovis aries (sheep) | 1.1375 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 2.9 | |
| Fatty-acid amide hydrolase 1 | Rattus norvegicus (Norway rat) | 5 | |
| Prostaglandin G/H synthase 2 | Mus musculus (house mouse) | 0.54 | |
| Solute carrier family 22 member 6 | Homo sapiens (human) | 8 | |
| Prostaglandin G/H synthase 1 | Rattus norvegicus (Norway rat) | 1.3 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (63.89) | 18.7374 |
| 1990's | 10 (27.78) | 18.2507 |
| 2000's | 2 (5.56) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (2.78) | 2.80 |
| Authors | Studies |
|---|---|
| Bochner, F; Evans, AM; Nation, RL; Sansom, LN; Somogyi, AA | 1 |
| Raineri-Gerber, I; von Felten, A | 1 |
| Cashman, SJ; Dollery, CT; Fuller, RW; Rees, AJ; Ritter, JM; Ward, PS | 1 |
| Barrow, SE; Cockcroft, JR; Minuz, P; Ritter, JM | 1 |
| Ganey, PE; Roth, RA | 1 |
| Needleman, P; Tripp, CS; Unanue, ER; Wyche, A | 1 |
| Wallenstein, MC | 1 |
| Demling, R; Katz, A; Lalonde, C; Ryan, P; West, K | 1 |
| Cox, SR; Gumbleton, TJ; Smith, RB; VanderLugt, JT | 1 |
| Bruss, ML; Emau, P; Giri, SN; Zia, S | 1 |
| Anderson, S; Baird, B; Brater, DC; Campbell, WB | 1 |
| Alexander, F; Hechtman, HB; Kobzik, L; Lelcuk, S; Shepro, D; Valeri, CR | 1 |
| Radha, E; Rao, GH; White, JG | 1 |
| Demling, RH; Hechtman, H; Lalonde, CC; Wenger, H; West, K; Wong, C | 1 |
| Alexander, F; Hechtman, HB; Huval, WV; Lelcuk, S; Mathieson, M; Shepro, D; Teoh, KH; Valeri, CR | 1 |
| Flynn, JT; Gee, MH; Havill, AM; Perkowski, SZ | 1 |
| Butler, RR; Cook, JA; Halushka, PV; Wise, WC | 1 |
| Allen, PD; Hechtman, HB; Huval, WV; Lelcuk, S; Mannick, JA; Shepro, D | 1 |
| Hill, RD; Hüttemeier, PC; Kong, D; Schuette, AH; Watkins, WD; Wonders, TR; Zapol, WM | 1 |
| Hoak, JC | 1 |
| Dunn, MJ | 1 |
| Butler, RR; Cook, JA; Halushka, PV; Rambo, W; Reines, HD; Wise, WC | 1 |
| Carson, SN; Hunter, GC | 1 |
| Andres, GA; Dunn, MJ; Lianos, EA | 1 |
| Cook, JA; Halushka, PV; Wise, WC | 1 |
| Coceani, F; Olley, PM | 1 |
| Coppo, PA; Hammerschmidt, DE; Jacob, HS; Xiu, RJ | 1 |
| Burckart, GJ; Diven, WF; Doyle, WJ; Evans, RW; Swarts, JD | 1 |
| Fletcher, JR; Khimenko, PL; Logsdon, P; Rizzo, A; Taylor, AE; Townsley, MI | 1 |
| Fiscus, RR; Han, C; Jones, SB; Wang, X; Yang, L | 1 |
| Altman, JD; Bache, RJ | 1 |
| Bernard, GR; Christman, BW; Dupont, WD; Fulkerson, WJ; Higgins, SB; Russell, JA; Schein, R; Steinberg, KP; Summer, WR; Swindell, BB; Wheeler, AP; Wright, PE | 1 |
| Bolognese, JA; Harper, SE; Hoover, ME; Lanza, FL; Quan, H; Rack, MF; Simon, TJ; Wilson, FR | 1 |
| Eikelboom, JW; McQuillan, A | 1 |
| Abad-Santos, F; Gallego-Sandín, S; Gálvez-Múgica, MA; García, AG; Gisbert, JP; Novalbos, J; Pajares, JM; Rosado, A | 1 |
| Hjemdahl, P; Stiller, CO | 1 |
3 review(s) available for thromboxanes and ibuprofen
| Article | Year |
|---|---|
Mechanisms of action: aspirin.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Endothelium; Humans; Ibuprofen; In Vitro Techniques; Indomethacin; Salicylates; Salicylic Acid; Thromboxanes | 1983 |
Role of prostaglandins, prostacyclin, and thromboxanes in the control of prenatal patency and postnatal closure of the ductus arteriosus.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Ductus Arteriosus; Ductus Arteriosus, Patent; Epoprostenol; Female; Ibuprofen; Indomethacin; Labor, Obstetric; Oxygen; Pregnancy; Prostaglandins; Prostaglandins E; Thromboxanes | 1980 |
Lessons from 20 years with COX-2 inhibitors: Importance of dose-response considerations and fair play in comparative trials.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Fibrinolytic Agents; Humans; Ibuprofen; Lactones; Naproxen; Prostaglandins; Prostaglandins I; Sulfones; Thromboxanes | 2022 |
7 trial(s) available for thromboxanes and ibuprofen
| Article | Year |
|---|---|
Effect of racemic ibuprofen dose on the magnitude and duration of platelet cyclo-oxygenase inhibition: relationship between inhibition of thromboxane production and the plasma unbound concentration of S(+)-ibuprofen.
Topics: Adult; Blood Coagulation; Blood Platelets; Cyclooxygenase Inhibitors; Humans; Ibuprofen; In Vitro Techniques; Male; Stereoisomerism; Thromboxanes | 1991 |
Effects of non-steroidal anti-inflammatory drugs on prostacyclin and thromboxane biosynthesis in patients with mild essential hypertension.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Pressure; Chromatography, Affinity; Epoprostenol; Female; Gas Chromatography-Mass Spectrometry; Humans; Hypertension; Ibuprofen; Kidney; Male; Middle Aged; Sulindac; Thromboxanes | 1990 |
Effects of ibuprofen, naproxen, and sulindac on prostaglandins in men.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Furosemide; Humans; Ibuprofen; Indenes; Kidney; Male; Naproxen; Prostaglandins; Random Allocation; Renin; Sulindac; Thromboxanes | 1985 |
Determinants of cardiovascular stability during abdominal aortic aneurysmectomy (AAA).
Topics: Aged; Aorta, Abdominal; Aortic Aneurysm; Blood Platelets; Epoprostenol; Female; Heart; Hematologic Tests; Hemodynamics; Humans; Ibuprofen; Ligation; Male; Middle Aged; Myocardial Contraction; Myocardial Infarction; Papillary Muscles; Pulmonary Wedge Pressure; Serotonin; Thromboxane A2; Thromboxanes | 1984 |
The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
Topics: Acidosis, Lactic; Double-Blind Method; Epoprostenol; Female; Fever; Hemodynamics; Humans; Ibuprofen; Male; Middle Aged; Oxygen Consumption; Respiratory Distress Syndrome; Sepsis; Shock; Survival Rate; Thromboxanes | 1997 |
Specific inhibition of cyclooxygenase-2 with MK-0966 is associated with less gastroduodenal damage than either aspirin or ibuprofen.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Duodenal Ulcer; Enzyme Inhibitors; Female; Humans; Ibuprofen; Isoenzymes; Lactones; Male; Membrane Proteins; Middle Aged; Prostaglandin-Endoperoxide Synthases; Stomach Ulcer; Sulfones; Thromboxanes | 1999 |
Effect of ibuprofen on cyclooxygenase and nitric oxide synthase of gastric mucosa: correlation with endoscopic lesions and adverse reactions.
Topics: Adolescent; Adult; Biopsy, Needle; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Enzyme-Linked Immunosorbent Assay; Female; Gastric Mucosa; Gastroscopy; Humans; Ibuprofen; Immunohistochemistry; Male; Nitric Oxide Synthase; Probability; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Reference Values; Risk Factors; Single-Blind Method; Thromboxanes | 2004 |
26 other study(ies) available for thromboxanes and ibuprofen
| Article | Year |
|---|---|
[Inhibition of thrombocyte function by non-steroidal anti-rheumatic agents: a comparative study between diclofenac, acemetacin, mefenamic acid and ibuprofen].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; Cyclooxygenase Inhibitors; Diclofenac; Humans; Ibuprofen; Indomethacin; Malondialdehyde; Mefenamic Acid; Platelet Aggregation; Thromboxanes | 1991 |
Excretion of metabolites of prostacyclin and thromboxane by rats with nephrotoxic nephritis: effects of interleukin-1.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Creatinine; Cyclooxygenase Inhibitors; Epoprostenol; Ibuprofen; In Vitro Techniques; Interleukin-1; Kidney Glomerulus; Male; Nephritis; Neutrophils; Rats; Rats, Inbred Strains; Thromboxane B2; Thromboxanes | 1991 |
Thromboxane does not mediate pulmonary vascular response to monocrotaline pyrrole.
Topics: Animals; Cyclooxygenase Inhibitors; Dibenzothiepins; Hypertension, Pulmonary; Ibuprofen; Imidazoles; Male; Monocrotaline; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; Pyrrolizidine Alkaloids; Rats; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane-A Synthase; Thromboxanes | 1987 |
The functional significance of the regulation of macrophage Ia expression by endogenous arachidonate metabolites in vitro.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Dinoprostone; Female; Histocompatibility Antigens Class II; Ibuprofen; Indomethacin; Macrophage Activation; Macrophages; Mice; Mice, Inbred Strains; Prostaglandins E; SRS-A; Thromboxanes | 1986 |
Attenuation of penicillin models of epilepsy by nonsteroidal anti-inflammatory drugs.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Brain; Cyclooxygenase Inhibitors; Disease Models, Animal; Epilepsy; Female; Ibuprofen; Mefenamic Acid; Penicillins; Prostaglandins; Rats; Rats, Inbred Strains; Thromboxanes | 1987 |
Topical ibuprofen decreases thromboxane release from the endotoxin-stimulated burn wound.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Topical; Animals; Blood Pressure; Burns; Endotoxins; Escherichia coli; Ibuprofen; Infusions, Parenteral; Lymph; Ointments; Oxygen; Skin Absorption; Thromboxane B2; Thromboxanes | 1986 |
Relationships between thromboxane production, platelet aggregability, and serum concentrations of ibuprofen or flurbiprofen.
Topics: Adult; Flurbiprofen; Humans; Ibuprofen; Platelet Aggregation; Propionates; Thromboxanes | 1987 |
Ibuprofen prevents Pasteurella hemolytica endotoxin-induced changes in plasma prostanoids and serotonin, and fever in sheep.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprost; Endotoxins; Female; Fever; Ibuprofen; Pasteurella; Pasteurella Infections; Prostaglandins; Prostaglandins F; Serotonin; Sheep; Sheep Diseases; Thromboxane B2; Thromboxanes | 1985 |
Prostacyclin and thromboxane A2 moderate postischemic renal failure.
Topics: 6-Ketoprostaglandin F1 alpha; Acute Kidney Injury; Animals; Epoprostenol; Ibuprofen; Ischemia; Male; Methacrylates; Premedication; Rats; Renal Circulation; Thromboxane A2; Thromboxane B2; Thromboxanes | 1985 |
Irreversible platelet aggregation does not depend on lipoxygenase metabolites.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cyclooxygenase Inhibitors; Epinephrine; Humans; Ibuprofen; Lipoxygenase; Lipoxygenase Inhibitors; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Thromboxanes | 1985 |
Endotoxin-induced prostanoid production by the burn wound can cause distant lung dysfunction.
Topics: Animals; Burns; Endotoxins; Hemodynamics; Ibuprofen; Injections, Intravenous; Lung Diseases; Lymph; Pulmonary Artery; Sheep; Thromboxane A2; Thromboxanes; Time Factors | 1986 |
Arachidonic acid metabolites mediate early burn edema.
Topics: Animals; Body Water; Burns; Calcium Channel Blockers; Capillary Permeability; Chromones; Edema; Ibuprofen; Ketoconazole; Male; Oxamic Acid; Rats; Rats, Inbred Strains; SRS-A; Thromboxanes | 1984 |
Role of intrapulmonary release of eicosanoids and superoxide anion as mediators of pulmonary dysfunction and endothelial injury in sheep with intermittent complement activation.
Topics: Animals; Capillary Permeability; Chemotaxis, Leukocyte; Complement Activation; Endothelium; Hypertension, Pulmonary; Hypoxia; Ibuprofen; Lung Diseases; Meclofenamic Acid; Models, Biological; Pulmonary Circulation; Sheep; Superoxides; Thromboxanes | 1983 |
Gentamicin and indomethacin in the treatment of septic shock: effects on prostacyclin and thromboxane A2 production.
Topics: Animals; Epoprostenol; Fatty Acids, Essential; Female; Fibrin Fibrinogen Degradation Products; Gentamicins; Ibuprofen; Imidazoles; Indomethacin; Macrophages; Male; Peritonitis; Prostaglandins; Prostaglandins F; Rats; Shock, Septic; Thromboxane A2; Thromboxane B2; Thromboxanes | 1983 |
Regional blood flow and pulmonary thromboxane release after sublethal endotoxin infusion in sheep.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Endotoxins; Escherichia coli; Hemodynamics; Ibuprofen; Lung; Prostaglandins F; Regional Blood Flow; Sheep; Thromboxane A2; Thromboxane B2; Thromboxanes | 1984 |
Role of eicosanoids in the control of renal function in severe hepatic disease.
Topics: Animals; Arachidonic Acids; Aspirin; Dogs; Humans; Ibuprofen; Indomethacin; Kidney; Lipoxygenase; Liver Cirrhosis; Phospholipases; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Regional Blood Flow; Thromboxanes; Vasoconstriction | 1984 |
The potential role of thromboxane and prostacyclin in endotoxic and septic shock.
Topics: Animals; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Epoprostenol; Fatty Acids; Gentamicins; Ibuprofen; Imidazoles; Methacrylates; Peritonitis; Rats; Rats, Inbred Strains; Shock, Septic; Thromboxane-A Synthase; Thromboxanes | 1984 |
Arterial wall thromboxane: dominance after surgery predisposes to thrombosis.
Topics: Animals; Blood Vessel Prosthesis; Carotid Arteries; Graft Occlusion, Vascular; Ibuprofen; Sheep; Thrombosis; Thromboxane A2; Thromboxanes | 1984 |
Glomerular prostaglandin and thromboxane synthesis in rat nephrotoxic serum nephritis. Effects on renal hemodynamics.
Topics: Animals; Blood Physiological Phenomena; Glomerular Filtration Rate; Glomerulonephritis; Ibuprofen; Kidney Glomerulus; Male; Methacrylates; Nephrotic Syndrome; Prostaglandin Antagonists; Prostaglandins; Rabbits; Rats; Rats, Inbred Strains; Renal Circulation; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes | 1983 |
Implications for thromboxane A2 in the pathogenesis of endotoxic shock.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprost; Disseminated Intravascular Coagulation; Fibrin Fibrinogen Degradation Products; Ibuprofen; Indomethacin; Male; Muridae; Prostaglandins E; Prostaglandins F; Shock, Septic; Thromboxane A2; Thromboxanes | 1981 |
Anisodamine inhibits thromboxane synthesis, granulocyte aggregation, and platelet aggregation. A possible mechanism for its efficacy in bacteremic shock.
Topics: Animals; Cell Aggregation; Cricetinae; Depression, Chemical; Granulocytes; Humans; Ibuprofen; Platelet Aggregation; Scopolamine Derivatives; Shock, Septic; Solanaceous Alkaloids; Structure-Activity Relationship; Thromboxane B2; Thromboxanes; Vasodilator Agents | 1982 |
Effect of ibuprofen treatment during experimental acute otitis media.
Topics: Acute Disease; Ampicillin; Animals; Chinchilla; Drug Therapy, Combination; Ear, Middle; Fatty Acids, Nonesterified; Haemophilus influenzae; Ibuprofen; Lymphocyte Count; Otitis Media; Thromboxanes | 1995 |
Platelet-activating factor increases vascular resistance in rat hindquarters by thromboxane A2.
Topics: Animals; Azepines; Blood Pressure; Capillary Permeability; Hindlimb; Ibuprofen; Male; Phenylacetates; Platelet Activating Factor; Rats; Rats, Wistar; Regional Blood Flow; Sulfonamides; Thromboxane A2; Thromboxanes; Triazoles; Vascular Resistance | 1995 |
Calcitonin gene-related peptide release in endotoxicosis may be mediated by prostaglandins.
Topics: Animals; Aspirin; Blood Glucose; Blood Pressure; Calcitonin Gene-Related Peptide; Cyclooxygenase Inhibitors; Drug Tolerance; Ibuprofen; Imidazoles; Indomethacin; Lactates; Lipopolysaccharides; Male; Prostaglandins; Rats; Rats, Sprague-Dawley; Rats, Wistar; Shock, Septic; Thromboxanes | 1995 |
The mechanism of coronary collateral vasoconstriction in response to cyclooxygenase blockade.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Collateral Circulation; Coronary Circulation; Cyclooxygenase Inhibitors; Dogs; Epoprostenol; Ibuprofen; Lipoxygenase Inhibitors; Thromboxanes; Vasoconstriction | 1994 |
Cyclooxygenase inhibitors and the antiplatelet effects of aspirin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Heart Diseases; Humans; Ibuprofen; Platelet Aggregation Inhibitors; Thromboxanes | 2002 |