Page last updated: 2024-09-02

thromboxanes and furegrelate

thromboxanes has been researched along with furegrelate in 15 studies

Compound Research Comparison

Studies
(thromboxanes)
Trials
(thromboxanes)
Recent Studies (post-2010)
(thromboxanes)
Studies
(furegrelate)
Trials
(furegrelate)
Recent Studies (post-2010) (furegrelate)
3,202149199109210

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19904 (26.67)18.7374
1990's8 (53.33)18.2507
2000's2 (13.33)29.6817
2010's0 (0.00)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Stanley, JC; Wakefield, TW; Wang, TW; Wirthlin, DJ; Wrobleski, SK1
Ji, TH; Murdoch, WJ; Slaughter, RG; Van Kirk, EA; Wilken, C1
Lakings, DB; Mohrland, JS; Vander Lugt, JT1
Bennett, WM; Scoggins, BA; Tresham, JJ; Whitworth, JA1
Cumming, AD; Lindsay, RM; Linton, AL; McDonald, JW; Solez, K1
Kaldunski, ML; Mattson, DL; Mistry, M; Nasjletti, A; Roman, RJ1
Aiken, JW; Gorman, RR; Johnson, RA; Spilman, CH1
Fitzpatrick, FA; Liggett, WF; Wynalda, MA1
Badahman, AH; Wilson, TW1
Belzer, FO; Saunder, A; Schilling, M; Southard, JH1
Forster, H; Takenaka, T1
Brands, MW; Hall, JE; Keen, HL; Shek, EW; Smith, MJ1
Hilbun, LR; Pallone, TL; Silldorff, EP1
Brockmann, MA; Giese, A; Kim, EL; Leppert, J; Nadrowitz, R; Schauff, AK; Wuestenberg, R1
Abdelazeem, H; Aljesri, K; Norel, X; Ozen, G; Topal, G; Turkyılmaz, G; Turkyılmaz, S1

Trials

1 trial(s) available for thromboxanes and furegrelate

ArticleYear
Multiple dose trial of the thromboxane synthase inhibitor furegrelate in normal subjects.
    European journal of clinical pharmacology, 1990, Volume: 38, Issue:5

    Topics: Adolescent; Adult; Benzofurans; Bleeding Time; Blood Coagulation; Blood Platelets; Half-Life; Humans; Intestinal Absorption; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Random Allocation; Thromboxane-A Synthase; Thromboxanes

1990

Other Studies

14 other study(ies) available for thromboxanes and furegrelate

ArticleYear
Increased prostacyclin and adverse hemodynamic responses to protamine sulfate in an experimental canine model.
    The Journal of surgical research, 1991, Volume: 50, Issue:5

    Topics: Animals; Benzofurans; Dogs; Epoprostenol; Hemodynamics; Indomethacin; Nitroprusside; Oxygen; Oxygen Consumption; Platelet Aggregation; Platelet Count; Protamines; Thromboxane-A Synthase; Thromboxanes; Veins

1991
Increased production of ovarian thromboxane in gonadotropin-treated immature rats: relationship to the ovulatory process.
    Prostaglandins, 1990, Volume: 40, Issue:6

    Topics: Animals; Benzofurans; Biphenyl Compounds; Chorionic Gonadotropin; Female; Gonadotropins; Gonadotropins, Equine; Indomethacin; Ovary; Ovulation; Rats; Rats, Inbred Strains; Thromboxane B2; Thromboxanes

1990
Cyclosporine-induced hypertension in sheep. The role of thromboxanes.
    Transplantation, 1990, Volume: 49, Issue:1

    Topics: Animals; Benzofurans; Cyclosporins; Dose-Response Relationship, Drug; Female; Glomerular Filtration Rate; Hypertension; Renin; Sheep; Thromboxanes

1990
The protective effect of thromboxane synthetase inhibition on renal function in systemic sepsis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1989, Volume: 13, Issue:2

    Topics: Animals; Benzofurans; Glomerular Filtration Rate; Kidney; Natriuresis; Peritonitis; Sheep; Shock, Septic; Thromboxane-A Synthase; Thromboxanes

1989
Influence of eicosanoids on renal function of DOCA-salt hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1988, Volume: 12, Issue:3

    Topics: Animals; Benzofurans; Body Water; Bridged Bicyclo Compounds, Heterocyclic; Desoxycorticosterone; Fatty Acids, Unsaturated; Hemodynamics; Hydrazines; Hypertension; Kidney; Male; Meclofenamic Acid; Prostaglandins; Rats; Rats, Inbred Strains; Renal Circulation; Sodium; Sodium Chloride; Thromboxanes

1988
Inhibition of platelet thromboxane A2 synthase activity by sodium 5-(3'-pyridinylmethyl)benzofuran-2-carboxylate.
    Prostaglandins, 1983, Volume: 26, Issue:2

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Benzofurans; Blood Platelets; Cyclic AMP; Dogs; Humans; Oxidoreductases; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1983
Sodium 5-(3'-pyridinylmethyl)benzofuran-2-carboxylate (U-63557A), a new, selective thromboxane synthase inhibitor: intravenous and oral pharmacokinetics in dogs and correlations with ex situ thromboxane B2 production.
    Prostaglandins, 1983, Volume: 26, Issue:2

    Topics: Administration, Oral; Animals; Benzofurans; Chromatography, High Pressure Liquid; Dogs; Half-Life; Injections, Intravenous; Kinetics; Oxidoreductases; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1983
A renal vasodilator effect of angiotensin II revealed by dual thromboxane inhibition.
    Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:6

    Topics: Angiotensin II; Animals; Benzofurans; Blood Pressure; Rats; Rats, Sprague-Dawley; Renal Circulation; Thromboxane-A Synthase; Thromboxanes; Vascular Resistance; Vasodilation

1994
Five-to-seven-day kidney preservation with aspirin and furegrelate.
    Transplantation, 1993, Volume: 55, Issue:4

    Topics: Animals; Aspirin; Benzofurans; Creatinine; Dogs; Female; Kidney; Kidney Transplantation; Organ Preservation; Prostaglandin Antagonists; Prostaglandins; Thromboxane-A Synthase; Thromboxanes; Time Factors

1993
Arginine vasopressin interacts with thromboxane in hydronephrosis.
    The American journal of physiology, 1997, Volume: 272, Issue:1 Pt 2

    Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Arterioles; Benzofurans; Bridged Bicyclo Compounds, Heterocyclic; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydrazines; Hydronephrosis; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Reference Values; Renal Circulation; Thromboxane-A Synthase; Thromboxanes; Vasoconstriction

1997
Inhibition of thromboxane synthesis attenuates insulin hypertension in rats.
    American journal of hypertension, 1997, Volume: 10, Issue:10 Pt 1

    Topics: Animals; Benzofurans; Glomerular Filtration Rate; Hyperinsulinism; Hypertension; Male; Potassium; Rats; Rats, Sprague-Dawley; Sodium; Thromboxane-A Synthase; Thromboxanes

1997
Angiotensin II constriction of rat vasa recta is partially thromboxane dependent.
    Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Angiotensin II; Animals; Benzofurans; Blood Vessels; Bridged Bicyclo Compounds, Heterocyclic; Culture Techniques; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Fatty Acids, Unsaturated; Female; Hydrazines; Indomethacin; Kidney Medulla; Kinetics; Lipoxygenase Inhibitors; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Thromboxane-A Synthase; Thromboxanes; Vasoconstriction; Vasoconstrictor Agents

2002
Inhibition of invasion-associated thromboxane synthase sensitizes experimental gliomas to gamma-radiation.
    Journal of neuro-oncology, 2009, Volume: 91, Issue:3

    Topics: Animals; Animals, Inbred Strains; Astrocytes; Benzofurans; Brain Neoplasms; Cell Survival; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Enzyme Inhibitors; Gamma Rays; Gene Expression Regulation, Neoplastic; Glioma; Humans; Mice; Neoplasm Invasiveness; Radiation Tolerance; Thromboxane-A Synthase; Thromboxanes; Time Factors; Transfection

2009
Comparative study on the effect of aspirin, TP receptor antagonist and TxA
    Life sciences, 2021, Dec-01, Volume: 286

    Topics: Arachidonic Acid; Aspirin; Benzofurans; Carbazoles; Enzyme Inhibitors; Female; Humans; Male; Mammary Arteries; Muscle, Smooth, Vascular; Phenylephrine; Receptors, Prostaglandin; Receptors, Thromboxane; Saphenous Vein; Sulfonamides; Thromboxane A2; Thromboxane-A Synthase; Thromboxanes; Vasoconstriction

2021