thromboxane-b2 has been researched along with cangrelor* in 1 studies
1 other study(ies) available for thromboxane-b2 and cangrelor
Article | Year |
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Adenosine and Forskolin Inhibit Platelet Aggregation by Collagen but not the Proximal Signalling Events.
The G protein-coupled receptor, adenosine A. This article investigates the effect of A. Washed human platelets were stimulated by collagen or the GPVI-specific agonist collagen-related peptide (CRP) in the presence of the adenosine receptor agonist, 5'-N-ethylcarboxamidoadenosine (NECA) or the adenylyl cyclase activator, forskolin and analysed for aggregation, adenosine triphosphate secretion, protein phosphorylation, spreading, Ca. NECA, a bioactive adenosine analogue, partially inhibits aggregation and secretion to collagen or CRP in the absence or presence of the P2Y. NECA and forskolin have no effect on the proximal signalling events by collagen. They inhibit platelet activation in a response-specific manner in part through inhibition of the feedback action of TxA Topics: Adenosine; Adenosine Monophosphate; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Blood Platelets; Carrier Proteins; Cells, Cultured; Colforsin; Collagen; Cyclic AMP; Feedback, Physiological; Humans; Indomethacin; Peptides; Platelet Aggregation; Platelet Membrane Glycoproteins; Receptor, Adenosine A2A; Signal Transduction; Thromboxane B2 | 2019 |